Staff Profile

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Career Summary

Biography

Dr Oldmeadow is the Senior Statistician at  the Clinical Research Design, Information Technology and Statistical Support (CReDITSS) unit,  located at the Hunter Medical Research Institute (HMRI).  Dr Oldmeadow has contributed to the design, analysis and data management of a number of large studies and has provided consultative and collaborative input to clinicians and public health specialists on a wide range of methodological problems.  He has a strong track-record in study design and co-ordinating the analytic plans of research projects.

Dr Oldmeadow  completed his PhD in late 2009 at the Queensland University of Technology, and his thesis was in the application and development of statistical methods in bioinformatics; specifically he developed a generalisation to the Bayesian segmentation and classification model for analysing DNA sequences from mulitple species to identify functional genomic regions. In 2010 Dr Oldmeadow joined the CReDITSS unit  as an HMRI post-doctoral research fellow.  His research interests are in statistical methodologies for Genetic Epidemiology, Bioinformatics, and Biostatistics.  An up-to-date list of his publications is at Google Citations ( http://scholar.google.com.au/citations?user=Lo70aGIAAAAJ )

 

 

Qualifications

  • PhD, Queensland University of Technology, 19/11/2009
  • Bachelor of Mathematics (Honours), University of Newcastle, 01/06/2005

Research

Research keywords

  • Bioinformatics
  • Biostatistics

Research expertise

Dr Oldmeadow's specific research interests are in Bayesian statistics, model selection, genomic segmentation, and causal modelling. He has published in high impact journals such as Molecular Biology and Evolution, Bioinformatics, and Genetic Epidemiology, and has co-authored articles appearing in Science and Nature Genetics.

Fields of Research

CodeDescriptionPercentage
010402Biostatistics85
060102Bioinformatics15

Teaching

Teaching keywords

  • Biostatistics

Teaching expertise

Has experience coordinating large post-graduate Biostatistics subjects both face-to-face and distance learning.

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Highlighted Publications

For publications that are currently unpublished or in-press, details are shown in italics.

YearCitationAltmetricsLink
2011Oldmeadow C, Keith JM, 'Model selection in Bayesian segmentation of multiple DNA alignments', BIOINFORMATICS, 27 604-610 (2011) [C1]
2011Oldmeadow CJ, Riveros RC, Holliday EG, Scott R, Moscato PA, Wang JJ, et al., 'Sifting the wheat from the chaff: Prioritizing GWAS results by identifying consistency across analytical methods', Genetic Epidemiology, 35 745-754 (2011) [C1]
2010Oldmeadow C, Mengersen K, Mattick JS, Keith JM, 'Multiple Evolutionary Rate Classes in Animal Genome Evolution', MOLECULAR BIOLOGY AND EVOLUTION, 27 942-953 (2010) [C1]

Publications

For publications that are currently unpublished or in-press, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Chapter (1 outputs)

YearCitationAltmetricsLink
2013Holliday EG, Oldmeadow CJ, Maguire JM, Attia JR, 'Candidate gene association studies in stroke', Stroke Genetics, Springer Verlag, London 9-23 (2013) [B1]

Journal article (26 outputs)

YearCitationAltmetricsLink
2014Oldmeadow C, Mossman D, Evans TJ, Holliday EG, Tooney PA, Cairns MJ, et al., 'Combined analysis of exon splicing and genome wide polymorphism data predict schizophrenia risk loci.', J Psychiatr Res, 52 44-49 (2014) [C1]
2014Algama M, Oldmeadow C, Tasker E, Mengersen K, Keith JM, 'Drosophila 3 ' UTRs Are More Complex than Protein-Coding Sequences', PLOS ONE, 9 (2014) [C1]
2014Abdullah N, Scott RJ, Attia J, Oldmeadow C, Holliday EG, 'The architecture of risk for type 2 diabetes: Understanding asia in the context of global findings', International Journal of Endocrinology, 2014 (2014)
2014Loth DW, Lahousse L, Hofman A, Uitterlinden AG, Stricker BH, Brusselle GG, et al., 'Genome-wide association analysis identifies six new loci associated with forced vital capacity', Nature Genetics, (2014)
2014Napthali K, Boyle M, Tran H, Schofield PW, Peel R, McEvoy M, et al., 'Thyroid antibodies, autoimmunity and cognitive decline: is there a population-based link?', Dement Geriatr Cogn Dis Extra, 4 140-146 (2014)
2014McCarthy-Jones S, Green MJ, Carr V, Scott RJ, Tooney PA, Cairns MJ, et al., 'Preliminary evidence of an interaction between the FOXP2 gene and childhood emotional abuse predicting likelihood of auditory verbal hallucinations in schizophrenia', Journal of Psychiatric Research, 50 66-72 (2014)
2014Moayyeri A, Hsu Y-H, Karasik D, Estrada K, Xiao S-M, Nielson C, et al., 'Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium', HUMAN MOLECULAR GENETICS, 23 3054-3068 (2014)
2014Gunathilake R, Krishnamurthy V, Oldmeadow C, Kerr E, Padmakumar C, Attia J, et al., 'Relationships between age, other predictive variables, and the 90-day functional outcome after intravenous thrombolysis for acute ischemic stroke', AUSTRALASIAN JOURNAL ON AGEING, 33 19-19 (2014)
2014Oldmeadow C, Holliday EG, McEvoy M, Scott R, Kwok JB, Mather K, et al., 'Concordance between Direct and Imputed APOE Genotypes using 1000 Genomes Data.', J Alzheimers Dis, (2014)
2013Williams N, Hardy BM, Tarrant S, Enninghorst N, Attia J, Oldmeadow C, Balogh ZJ, 'Changes in hip fracture incidence, mortality and length of stay over the last decade in an Australian major trauma centre.', Archives of Osteoporosis, 8 (2013) [C1]
2013Ranasinghe WKB, Attia J, Oldmeadow C, Lawrentschuk N, Robertson J, Ranasinghe T, et al., 'Bladder carcinoma in situ (CIS) in Australia: a rising incidence for an under-reported malignancy', BJU International, 112 46-52 (2013) [C1]
2013Holliday S, Magin P, Oldmeadow C, Attia J, Dunbabin J, Henry J, et al., 'An examination of the influences on New South Wales general practitioners regarding the provision of opioid substitution therapy', Drug and Alcohol Review, 32 495-503 (2013) [C1]
2013Holliday S, Magin P, Dunbabin J, Oldmeadow C, Henry J-M, Lintzeris N, et al., 'An Evaluation of the Prescription of Opioids for Chronic Nonmalignant Pain by Australian General Practitioners', PAIN MEDICINE, 14 62-74 (2013) [C1]
2013Kottgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, et al., 'Genome-wide association analyses identify 18 new loci associated with serum urate concentrations', Nature Genetics, 45 145-154 (2013) [C1]
2013Gunathilake R, Oldmeadow C, McEvoy M, Kelly B, Inder K, Schofield P, Attia J, 'Mild Hyponatremia Is Associated With Impaired Cognition And Falls In Community-Dwelling Older Persons', Journal of the American Geriatrics Society, 61 1838-1839 (2013) [C1]
2013Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, et al., 'GWAS of 126,559 individuals identifies genetic variants associated with educational attainment', Science, 340 1467-1471 (2013) [C1]
2012Okada Y, Sim X, Go MJ, Wu J-Y, Gu D, Takeuchi F, et al., 'Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations', Nature Genetics, 44 904-909 (2012) [C1]
2012Yoshino O, Quail AW, Oldmeadow CJ, Balogh ZJ, 'The interpretation of intra-abdominal pressures from animal models: The rabbit to human example', Injury: International Journal of the Care of the Injured, 43 169-173 (2012) [C1]
2012Collins NJ, Hatton R, Ng K, Bhagwandeen R, Attia JR, Oldmeadow CJ, Jayasinghe R, 'Percutaneous device closure of patent foramen ovale using the premere occlusion device: Initial experience, procedural, and intermediate-term results', Journal of Invasive Cardiology, 24 164-168 (2012) [C1]

Co-authors: John Attia

2012Holliday EG, Maguire JM, Evans T-J, Koblar SA, Jannes J, Sturm J, et al., 'Common variants at 6p21.1 are associated with large artery atherosclerotic stroke', Nature Genetics, 44 1147-1153 (2012) [C1]
2012Lynagh MC, Bonevski B, Sanson-Fisher RW, Symonds IM, Scott A, Hall AE, Oldmeadow CJ, 'An RCT protocol of varying financial incentive amounts for smoking cessation among pregnant women', BMC Public Health, 12 1032 (2012) [C3]
2011Oldmeadow CJ, Riveros RC, Holliday EG, Scott R, Moscato PA, Wang JJ, et al., 'Sifting the wheat from the chaff: Prioritizing GWAS results by identifying consistency across analytical methods', Genetic Epidemiology, 35 745-754 (2011) [C1]
2011Oldmeadow C, Keith JM, 'Model selection in Bayesian segmentation of multiple DNA alignments', BIOINFORMATICS, 27 604-610 (2011) [C1]
2010Oldmeadow C, Mengersen K, Mattick JS, Keith JM, 'Multiple Evolutionary Rate Classes in Animal Genome Evolution', MOLECULAR BIOLOGY AND EVOLUTION, 27 942-953 (2010) [C1]
2009Oldmeadow C, Mengersen K, Martin N, Duffy DL, 'Heritability and linkage analysis of appendicitis utilizing age at onset', Twin Research and Human Genetics, 12 150-157 (2009) [C1]
2008Oldmeadow C, Wood I, Mengersen K, Visscher PM, Martin NG, Duffy DL, 'Investigation of the relationship between smoking and appendicitis in Australian twins', ANNALS OF EPIDEMIOLOGY, 18 631-636 (2008) [C1]
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Conference (3 outputs)

YearCitationAltmetricsLink
2013Lynagh MC, Bonevski B, Sanson-Fisher R, Symonds I, Scott A, Hall A, Oldmeadow C, 'Should we pay pregnant smokers to quit? Preliminary findings of a feasibility trial.', Journal of Smoking Cessation, Sydney (2013) [E3]
2012Ranasinghe WKB, Attia JR, Oldmeadow CJ, Lawrentschuk N, Robertson J, Ranasinghe T, et al., 'Bladder carcinoma in situ in Australia: A rising incidence for an under-reported malignancy', Asia-Pacific Journal of Clinical Oncology, Darling Harbour, Sydney (2012) [E3]

Co-authors: John Attia

2012Holliday S, Magin PJ, Dunbabin JS, Oldmeadow CJ, Henry J-M, Lintzeris N, et al., 'Motivating factors amongst NSW general practitioners regarding the prescription of opioid substitution therapy', Drug and Alcohol Review, Melbourne, Australia (2012) [E3]
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Grants and Funding

Summary

Number of grants3
Total funding$75,656

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2015 (1 grants)

Improving uptake of colorectal screening among primary care attendees.$17,000
Funding Body: Australian Rotary Health

Project Team
Ms Natalie Dodd, Laureate Professor Robert Sanson-Fisher, Doctor Mariko Carey, Doctor Christopher Oldmeadow
SchemeRole
PhD ScholarshipInvestigator
Total AmountFunding StartFunding Finish
$17,00020152018
GNo:G1400854

2014 (1 grants)

A regional primary care based intervention to encourage colorectal cancer screening in those not responding to current national screening initiatives. $10,000
Funding Body: University of Newcastle

Project Team
Laureate Professor Robert Sanson-Fisher, Doctor Christopher Oldmeadow, Associate Professor Frans Henskens, Doctor Marita Lynagh
SchemeRole
Near Miss GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020142014
GNo:G1301403

2013 (1 grants)

Providing tailored web-based information to support colorectal cancer patients in their preparation for and recovery from surgery: A feasibility study$48,656
Funding Body: Cancer Institute NSW

Project Team
Laureate Professor Robert Sanson-Fisher, Dr Stephen Smith, Doctor Sancha Robinson, Ms Gill Batt, Associate Professor Frans Henskens, Conjoint Associate Professor Ross Kerridge, Doctor Christopher Oldmeadow, Doctor Peter Pockney, Doctor Christopher Hayes
SchemeRole
Evidence to Practice GrantInvestigator
Total AmountFunding StartFunding Finish
$48,65620132013
GNo:G1300868
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Research Supervision

Number of current supervisions2
Total current UoN PhD EFTSL0.5

For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20122016PhD (Medical Genetics)Co-SupervisorGenetic and Non-Genetic Studies of Type 2 Diabetes in Three Susceptible Asian Populations: Malay, Chinese and Indian
20112015PhD (CommunityMed & ClinEpid)Co-SupervisorMultidrug Resistance Tuberculosis (MDR-TB) in Community Setting of Bangladesh
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Dr Christopher Oldmeadow

Work Phone(+612) 40420499
Fax(+612) 4913848
Email
PositionConjoint Senior Lecturer
CReDITSS - HMRI
School of Medicine and Public Health
Faculty of Health and Medicine
The University of Newcastle, Australia
Office
Hunter Medical Research Institute,
John Hunter Hospital
URL:www.newcastle.edu.au/profile/christopher-oldmeadow
Link http://www.newcastle.edu.au/profile/christopher-oldmeadow