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Professor Shu Chuen Li

Professor

School of Biomedical Sciences and Pharmacy (Pharmacy and Experimental Pharmacology)

Career Summary

Biography

Professor Shu Chuen Li is Chair Professor and Discipline Convenor, Discipline of Pharmacy and Experimental Pharmacology. Before taking up the present position, Professor Li has worked as an academic at the National University of Singapore and as Acting Director and Deputy Director, Pharmaceutical Evaluation Section (PES) of Pharmaceutical Benefits Branch, Commonwealth Department of Health & Ageing in Canberra. During his period in Singapore, besides his academic appointment, Professor Li also served as the Visiting Specialist and Consultant to the Health Sciences Authority (which is the Singaporean equivalent of FDA in the USA and TGA in Australia). In this capacity, Professor Li has been instrumental in developing the Pharmacoeconomics and Drug Utilization Unit at the Centre for Drug Administration, Health Sciences Authority and in organizing several of the first ever pharmaceoconomics and outcomes conferences in the region. In his capacity as Acting Director and Deputy Director of PES in Australia, Professor Li was among the few pioneers that put the principles of pharmacoeconomic evaluation into practice for regulatory affairs, and has been involved in the implementation of the first version of the Australian Pharmacoeconomics Guidelines and the development of the second version of the same Guidelines. Professor Li has been very active in his research area of pharmacoeconomics and outcomes research as well as pharmacy practice. He has published more than 250 peer review articles and conference abstracts on the subjects. In the past few years, Professor Li has been invited to present more than 100 lectures and panel speeches about pharmacy practice, drug policies and pharmacoeconomic applications in various countries and jurisdictions. Professor Li was a Director on the ISPOPR Board of Directors from 2006 to 2008, and a founding member of the ISPOR Asia Consortium. Based in the United States, ISPOR is the peak academic society on pharmacoeconomics and outcomes research worldwide. Besides the aforementioned commitments, Professor Li also holds many other consultative positions in Australia and in various Asian countries. The main ones include: 1. Visiting Professor, Department of Pharmacy, National University of Singapore 2. Visiting Professor, School of Pharmacy, Fudan University, China 3. Visiting Professor, Faculty of Pharmaceutical Science, Prince of Songkla University in Thailand. 4.Visiting Specialist/Consultant, Centre for Drug Administration, Health Sciences Authority, Singapore 5. Visiting Specialist/Consultant, Centre for Health Services Research, Yong Loo Lin School of Medicine, National University of Singapore. Research Expertise
I have been involved with research in clinical pharmacy for more than 20 years. Recently, my research interest has been concentrated more on the areas of pharmacoeconomics and outcomes research, as well as drug policy. As a matter of fact, I would be considered as one of the pioneers in applying pharmacoeconomics in drug regulation, as I was involved with the first implementation of the first ever published pharmacoeconomics guidelines in drug reimbursement when I worked for the Commonwealth Government in Australia.

Teaching Expertise
I have been teaching pharmacoeconomics and outcomes research as well as pharmacotherapy for nearly 10 years. I have also been invited to provide lectures and workshops around the South-east Asian region during my period working at the National University of Singapore. I have also conducted courses for critical literature evaluation and biostatistics at the graduate level for nearly 10 years.

Administrative Expertise
I have been the acting director and deputy director at one of the Commonwealth Government department in Canberra for around 5 years. Before that I held senior pharmacist position as well as chief pharmacist and chief hospital administrator in Republic of Nauru for a period of 2 years. During the course of my career, I have been involved in handling many adminsitrative decisions and I have completed a degree of Master of Business Administration to provide the theoretcial consolidation of my administrative experience.

Collaborations

Qualifications

  • PhD, Monash University
  • Bachelor of Pharmacy, South Australian Institute of Technology
  • Master of Applied Science, South Australian Institute of Technology
  • Post Graduate Diploma in Management, Deakin University
  • Health Economics (Distance Education), Monash University

Keywords

  • Biostatistics
  • Clinical Pharmacy
  • Clinical Pharmacy Practice
  • Cost-effectiveness studies
  • Critical Literature Evaluation
  • Drug Policy
  • Health economics
  • Health services research
  • Outcomes Research
  • Patient reported outcomes studies
  • Pharmacoeconomics
  • Pharmacoepidemiology
  • Pharmacotherapeutics

Languages

  • Cantonese (Fluent)
  • Hakka (Fluent)
  • Mandarin (Fluent)

Fields of Research

Code Description Percentage
110399 Clinical Sciences not elsewhere classified 45
111799 Public Health and Health Services not elsewhere classified 40
111299 Oncology and Carcinogenesis not elsewhere classified 15

Professional Experience

UON Appointment

Title Organisation / Department
Professor University of Newcastle
School of Biomedical Sciences and Pharmacy
Australia

Academic appointment

Dates Title Organisation / Department
1/05/2007 -  Visiting Professor Fudan University
China
1/04/2007 - 22/06/2015 Visiting Professor National University of Singapore
Singapore
1/05/2006 -  Board of Directors International Society of Pharmacoeconomics & Outcomes Research (ISPOR)
United States
1/05/1998 - 1/12/2006 Associate Professor National University of Singapore
Department of Pharmacy
Singapore
1/09/1997 - 1/05/1998 Acting Director Commonwealth Department of Health and Family Services
Australia
1/07/1995 - 1/08/1997 Deputy Director

Drug regulation

Commonwealth Department of Health and Family Services
Australia
1/01/1992 - 1/12/1993 Special Subject Lecturer Monash University
Australia
1/01/1978 - 1/01/1979 Graduate Trainee Pharmacist Royal Adelaide Hospital
Department of Pharmacy
Australia

Professional appointment

Dates Title Organisation / Department
1/07/2001 -  Consultant/Visitng Specialist Centre for Drug Administration, Ministry of Health, Republic of Singapore
Singapore
1/03/1994 - 1/07/1994 Senior Pharmacist & Clinical Trials Coordinator Alfred Hospital
Department of Pharmacy
Australia
1/04/1985 - 1/03/1994 Clinical Pharmacist (Research & Education) Alfred Hospital
Department of Clinical Pharmacology
Australia
1/01/1983 - 1/02/1985 Chief Pharmacist & Chief Administrative Officer Nauru Phosphate Corporation Hospital, Republic of Nauru
Nauru Phospohate Corporation Hospital, Republic of Nauru
Papua New Guinea
1/02/1982 - 1/08/1982 Pharmacy manager Evans Pharmacy
Kimba in South Australia
Australia

Invitations

Participant

Year Title / Rationale
2007 Health Policy Dinner Symposium
Organisation: Fudan University and Chinese University of Hong Kong
2007 Conference on Quality of Life in Asia
Organisation: Hong Kong Society for Quality of Life, Academy of Medicine
2006 Symposium on New Standard for Hepatitis B Management
Organisation: Chapter of Gastroenterologists, College of Physicians, Singapore
2006 Third International Asian Conference on Cancer Screening
Organisation: Health Promotion Board
2006 Pre-Conference Workshop at ISPOR 2nd Asia Pacific Conference
Organisation: ISPOR
2006 IMS Special Symposium at ISPOR 2nd Asia Pacific Conference
Organisation: IMS & ISPOR
2006 Co-sponsor Special Session at ISPOR 2nd Asia Pacific Conference
Organisation: ISPOR & Various regulatory authroities in Asia
2006 Faculty of Science Lunchtime Seminar
Organisation: Faculty of Science, National University of Singapore
2006 Continuous Education Lecture
Organisation: Pharmaceutical Society of Singapore Industry Chapter
2006 15th Annual Scientific Meeting
Organisation: Singapore General Hospital
2006 Advanced GCP course on Pharmacovigilance
Organisation: Yong Loo Lin School of Medicine, National University of Singapore
2006 Training Workshop for National Healthcare Group College
Organisation: National Healthcare Group
2006 Second Regional Conference on Cost-effective Healthcare
Organisation: SingHealth Postgraduate Medical Institute
2005 Third Asia Pacific Evidence-Based Medicine Conference and Workshop,
Organisation: National University of Singapore & McMaster University of Canada
2005 Invited Talk
Organisation: Centre for Pharmaceutical Administration, Health Sciences Authority
2005 Pfizer Global Pharmaceuticals Outcomes Research Training Programme Part 1
Organisation: Pfizer Asia
2005 Presentation Talk at Science Focus for Teachers Program
Organisation: Ministry of Education & Faculty of Science, National University of Singapore
2005 Intervarsity Symposium Singapore, 17th Singapore Pharmacy Congress
Organisation: Pharmaceutical Society of Singapore & National University of Singapore
2005 Patient Reported Outcomes for Clinical Research Workshop.17th Singapore Pharmacy Congress
Organisation: Pharmaceutical Society of Singapore
2005 Dinner Symposium of Osteoporosis Society of Singapore
Organisation: Osteoporosis Society of Singapore Special Interest Group Meeting,
2005 Pfizer Outcomes Research Coordinators of Asia Training Program Part 2
Organisation: Pfizer Asia
2005 COFM Public Health Update Forum
Organisation: Chapter of Public Health & Occupational Physicians, Academy of Medicine, Singapore and Department of Community, Occupational and Family Medicine, Faculty of Medicine, National University of Singapore.
2005 Health Economic Symposium
Organisation: Vietnamese Ministry of Health & Sanofi-Aventis
2005 TASPOR Annual Health Economics Meeting and Symposium
Organisation: TASPOR
2005 21st Federation of Asian Pharmaceutical Associations (FAPA) Congress
Organisation: FAPA
2004 Invited Lecture
Organisation: at Faculty of Pharmaceutical Sciences, Prince of Songkla University
2004 Regional Conference on Cost-effective Healthcare
Organisation: SGH Postgraduate Medical Institute Healthcare Management Development Programme
2004 Medical Decision Workshop
Organisation: Tan Tock Seng Hospital, Singapore, Institute of Medical Education and Training (IMET), NHG College
2004 1st National Health Outcomes Conference
Organisation: Association Of Public Health Medical Specialist and Pfizer Malaysia Sdn. Bhd
2004 Post Conference Workshop, 1st National Health Outcomes Conference
Organisation: Association Of Public Health Medical Specialist and Pfizer Malaysia Sdn. Bhd
2004 Regional Conference on Cost-effective Healthcare,
Organisation: SGH Postgraduate Medical Institute Healthcare Management Development Programme
2004 . Pre-Conference Workshop, Regional Conference on Cost-effective Healthcare,
Organisation: SGH Postgraduate Medical Institute Healthcare Management Development Programme
2004 2nd VALID Steering Committee Meeting
Organisation: Sanofi-Aventis
2003 Proceedings of International Congress of Indian Pharmacy Graduate
Organisation: Pharmaceutical Society of India
2003 Dinner Symposium: New advances on lipid lowering therapy.
Organisation: Pharmaceutical Society of Singapore
2003 1st VALID Study Steering Committee Meeting,
Organisation: Sanofi-Aventis
2003 Panel Discussion at ISPOR First Asian Pacific Conference
Organisation: ISPOR
2003 Pre-conference workshop of ISPOR First Asian Pacific Conference
Organisation: ISPOR
2003 Roundtable Discussion for Chinese Delegation. ISPOR First Asian Pacific Conference,
Organisation: GSK
2003 1st National Health Outcomes and Pharmacoeconomics Symposium
Organisation: National University of Singapore, Pfizer Asia and Tan Tock Seng Hospital
2002 Invited Lecture
Organisation: Institute of Health Economics and Policy
2002 Invited Lecture
Organisation: Kyoto University
2002 International Workshop on Pharmacoeconomics:
Organisation: Indonesian Ministry of Health
2002 Invited Lecture
Organisation: University of Tokyo
2002 Asian Pacific Forum on New Therapies in Rheumatic Diseases.
Organisation: National Arthritis Foundation
2002 Invited Lecture
Organisation: National Healthcare Group P & T Co-ordinating Committee
2002 Workshop on Healthcare Financing
Organisation: Pharmaceutical Association of Malaysia
2002 15th Singapore Pharmacy Congress
Organisation: Pharmaceutical Society of Singapore
2002 Pharmacoeconomics for Pharmacists Workshop
Organisation: Pharmaceutical Society of Singapore
2001 Invited Lecture
Organisation: Centre of Pharmaceutical Administration, Health Sciences Authority
2001 First International Pharmaceutical Students Federation Asian Pacific Symposium
Organisation: IPSF of FIP
2001 Third Annual Scientific Meeting
Organisation: Johor State Department of Health
2001 An Evidence Based and Pharmacoeconomic Approach to Drug Prescribign Seminar
Organisation: National University Hospital Pharmacy and Therapeutics Committee
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Journal article (181 outputs)

Year Citation Altmetrics Link
2017 Mohd-Tahir N-A, Li S-C, 'Economic burden of osteoporosis-related hip fracture in Asia: a systematic review.', Osteoporos Int, (2017)
DOI 10.1007/s00198-017-3985-4
2017 Chan CL, Ang PS, Li SC, 'A Survey on Pharmacovigilance Activities in ASEAN and Selected Non-ASEAN Countries, and the Use of Quantitative Signal Detection Algorithms', Drug Safety, 40 517-530 (2017)

© 2017, Springer International Publishing Switzerland.Introduction: Most Countries have pharmacovigilance (PV) systems in place to monitor the safe use of health products. The pr... [more]

© 2017, Springer International Publishing Switzerland.Introduction: Most Countries have pharmacovigilance (PV) systems in place to monitor the safe use of health products. The process involves the detection and assessment of safety issues from various sources of information, communicating the risk to stakeholders and taking other relevant risk minimization measures. Objectives: This study aimed to assess the PV status in Association of Southeast Asian Nation (ASEAN) countries, sources for postmarket safety monitoring, methods used for signal detection and the need for a quantitative signal detection algorithm (QSDA). Comparisons were conducted with centres outside ASEAN. Methods: A questionnaire was sent to all PV centres in ASEAN countries, as well as seven other countries, from November 2015 to June 2016. The questionnaire was designed to collect information on the status of PV, with a focus on the use of a QSDA. Results: Data were collected from nine ASEAN countries and seven other countries. PV activities were conducted in all these countries, which were at different stages of development. In terms of adverse drug reaction (ADR) reports, the average number received per year ranged from 3 to 50,000 reports for ASEAN countries and from 7000 to 1,103,200 for non-ASEAN countries. Thirty-three percent of ASEAN countries utilized statistical methods to help detect signals from ADR reports compared with 100% in the other non-ASEAN countries. Eighty percent agreed that the development of a QSDA would help in drug signal detection. The main limitation identified was the lack of knowledge and/or lack of resources. Conclusion: Spontaneous ADR reports from healthcare professionals remains the most frequently used source for safety monitoring. The traditional method of case-by-case review of ADR reports prevailed for signal detection in ASEAN countries. As the reports continue to grow, the development of a QSDA would be useful in helping detect safety signals.

DOI 10.1007/s40264-017-0510-9
2017 Zhang F, He X, Xiang W, Li SC, 'Assessment of the quality of pharmacoeconomic evaluation literature in China', Journal of Medical Economics, 20 510-517 (2017)

© 2017 Informa UK Limited, trading as Taylor & Francis Group.Objective: To evaluate the quality of Chinese pharmacoeconomic-evaluation literature published between 2012¿2014 ret... [more]

© 2017 Informa UK Limited, trading as Taylor & Francis Group.Objective: To evaluate the quality of Chinese pharmacoeconomic-evaluation literature published between 2012¿2014 retrieved from the Chinese National Knowledge Infrastructure (CNKI) in order to assess their adherence to recommendations of the Chinese Pharmacoeconomic Guidelines. Methods: Identified literature was screened according to pre-specified criteria to access legibility for inclusion. Each included piece of literature was systematically compared against the recommendations proposed by the relevant Chinese guidelines. Results: After culling, 259 studies were included in the comparative analysis. When compared to a previous study evaluating the quality of similar literature published between 1997¿2007, the results showed improvements in certain technical aspects over the years. Particularly, an improvement was observed in more diverse evaluation methods being used, increased use of cost-utility analysis (2.43% in 2012¿2014 vs 0.26% in 1997¿2007) and use of discounting (45% in 2012¿2014 vs 4.35% in 1997¿ 2007). In addition, a small number of studies were starting to apply modeling. Conclusion: The quality of economic evaluation literature has improved in recent years, with more researchers realizing the importance and necessity of using discounting, sensitivity analysis, and modeling when conducting economic evaluation. This study also highlights certain important areas needing further attention when conducting economic evaluations in China. These include the ICER threshold of economic analysis, more detailed guidance in performing sensitivity analysis and modeling, as well as transferability of cost data across different regions. Overall, the results would support the positive contribution of the Chinese Economic Guideline in promoting economic evaluations in China.

DOI 10.1080/13696998.2017.1280501
2017 Hu H, Luan L, Yang K, Li SC, 'Burden of rheumatoid arthritis from a societal perspective: A prevalence-based study on cost of illness for patients with rheumatoid arthritis in China', International Journal of Rheumatic Diseases, (2017)

© 2017 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.Aim: To provide a comprehensive estimation of the economic burden of rheumatoid a... [more]

© 2017 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.Aim: To provide a comprehensive estimation of the economic burden of rheumatoid arthritis (RA) in China, especially for patients from less developed areas, and to explore the cost transferability between regions to assist healthcare decision-making. Methods: The study was conducted in south and north China from May 2013 to December 2013. The burden of RA was investigated by interviewing participants with a questionnaire battery containing socio-demographic, cost of illness (COI) and medical treatments. The COI questionnaire captured direct, indirect and intangible costs. Direct costs included hospitalizations, outpatient visits and medications. Indirect costs were estimated using the human capital approach, and intangible costs valued through the willingness-to-pay approach. All cost data were converted to 2013 US dollars by purchasing power parity, and then summarized descriptively and analyzed with mixed models. Results: Questionnaires were administered to 133 RA patients. The average direct costs were $1917.21 ± $2559.06 per patient year, with medications at $1283.89 ± $1898.15 comprising more than 50% of the total. The average indirect costs were $492.88 ± $1739.74 per patient year, while intangible costs were $20396.30 ± $31145.10. There was no significant difference detected between regions. Recent hospitalization was tested as a significant predictor of the direct costs. Age and income were significantly associated with indirect and intangible costs. Conclusions: Besides the substantial burden in terms of direct medical costs and productivity lost, there were notable intangible costs, especially among older patients. This conclusion could be potentially expanded to other provinces in China or even other countries through the adjustments for transferability.

DOI 10.1111/1756-185X.13028
2017 Chan CL, Rudrappa S, Ang PS, Li SC, Evans SJW, 'Detecting Signals of Disproportionate Reporting from Singapore's Spontaneous Adverse Event Reporting System: An Application of the Sequential Probability Ratio Test.', Drug Saf, (2017)
DOI 10.1007/s40264-017-0531-4
2016 Gao L, Hu H, Zhao F-L, Li S-C, 'Can the Direct Medical Cost of Chronic Disease Be Transferred across Different Countries? Using Cost-of-Illness Studies on Type 2 Diabetes, Epilepsy and Schizophrenia as Examples', PLOS ONE, 11 (2016) [C1]
DOI 10.1371/journal.pone.0147169
Citations Scopus - 1Web of Science - 1
2016 Li W, Yang J, Zhu XS, Li SC, Ho PC, 'Correlation between tea consumption and prevalence of hypertension among Singaporean Chinese residents aged =40 years', Journal of Human Hypertension, 30 11-17 (2016) [C1]

© 2016 Macmillan Publishers Limited.By a cross-sectional epidemiology study, we attempted to correlate the consumption of tea and/or health supplements, living habits and socio-d... [more]

© 2016 Macmillan Publishers Limited.By a cross-sectional epidemiology study, we attempted to correlate the consumption of tea and/or health supplements, living habits and socio-demographic factors to the prevalence of hypertension among Singaporean Chinese residents. Singaporean Chinese residents aged =40 years were randomly selected and interviewed face-to-face by clinical research assistants. Hypertension was defined as measured systolic blood pressure at least 140 mm Hg and/or diastolic blood pressure at least 90mmHg or self-reported history/treatment for hypertension. The prevalence of hypertension among the whole investigated population (N=1184, 58.27% females) was 49.73% and the prevalence increased to 66.47% in the sub-population aged =60 years. High risk of hypertension was associated with age =60 years (odds ratio (OR): 4.15-4.19, P<0.01), obesity (body mass index >25 kg m -2, OR: 2.10-2.11, P<0.01), family history of hypertension (OR: 2.69-2.76, P<0.01), diabetes history (OR: 2.29-2.33, P<0.01), hyperlipidemia history (OR: 1.79-1.80, P<0.01), male (OR: 1.56-1.59, P<0.01) and coffee intake (OR: 1.44-1.46, P<0.05). In contrast, drinking green tea at least 150 ml per week was associated with lower hypertension risk (OR: 0.63, 95% confidence interval (CI): 0.43-0.91, P<0.05). Drinking combination of green tea and British tea was associated with higher reduction in the risk of hypertension (OR: 0.58, 95% CI: 0.39-0.85, P<0.05). This cross-sectional study suggests that consumption of tea, especially green tea and British tea, was associated with lowering the risk of hypertension. On the other hand, consumption of coffee could be a risk factor of hypertension. These findings may provide useful information for health promotion to reduce risk of hypertension and warrant further study to confirm and elucidate such association.

DOI 10.1038/jhh.2015.45
2016 Zhang F, Xiang W, Li CY, Li SC, 'Economic burden of irritable bowel syndrome in China', World Journal of Gastroenterology, 22 10450-10460 (2016) [C1]

© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.AIM To estimate annual direct and indirect costs for patients diagnosed with irritable bow... [more]

© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.AIM To estimate annual direct and indirect costs for patients diagnosed with irritable bowel syndrome (IBS) and subtypes. METHODS Patients completed a standardized questionnaire concerning usage of healthcare resources, travel costs, meals, and productivity loss of patients when seeking treatment for IBS. Total annual costs per patient were calculated as the sum of direct (including medical and nonmedical) and indirect costs. Total annual costs per patient among various IBS subtypes were compared. Analysis of variance and bootstrapped independent sample t -tests were performed to determine differences between groups after controlling for IBS subtypes. RESULTS A total of 105 IBS patients (64.80% female), mean age of 57.12 years ± 10.31 years), mean disease duration of 4.31 years ± 5.40 years, were included. Total annual costs per patient were estimated as CNY18262.84 (USD2933.08). Inpatient and outpatient healthcare use were major cost drivers, accounting for 46.41%and 23.36% of total annual costs, respectively. Productivity loss accounted for 25.32% of total annual costs. The proportions of direct and indirect costs were similar to published studies in other countries. Nationally, the total costs of managing IBS would amount to CNY123.83 billion (USD1.99 billion). Among the IBS subtypes, total annual costs per patient of IBS-M was highest at CNY18891.18 (USD3034). Furthermore, there was significant difference in productivity loss among IBS subtypes (P = 0.031). CONCLUSION IBS imposes a huge economic burden on patients and healthcare systems, which could account for 3.3% of the total healthcare budget for the entire Chinese nation. More than two-thirds of total annual costs of IBS consist of inpatient and outpatient healthcare use. Among the subtypes, IBS-M patients appear to have the greatest economic burden but require further confirmation.

DOI 10.3748/wjg.v22.i47.10450
2016 Koh L, Glaetzer C, Chuen Li S, Zhang M, 'Health Technology Assessment, International Reference Pricing, and Budget Control Tools from China's Perspective: What Are the Current Developments and Future Considerations?', Value in Health Regional Issues, 9 15-21 (2016) [C1]

© 2015.Background: China is investing considerably in health care reforms to address issues in its health care system. An example is access to innovative drugs, which remains cha... [more]

© 2015.Background: China is investing considerably in health care reforms to address issues in its health care system. An example is access to innovative drugs, which remains challenging because it is largely dependent on patient self-pay. Recognizing this, the government has invested considerably in its basic medical insurance. As health care expenditure increases, there are growing concerns on budget control. Several health policy tools have been discussed recently such as health technology assessment, international reference pricing, and hospital budget control tools, which can be viewed as addressing the affordability concerns of the government budget. China has also listed her health outcomes goals in "Healthy China 2020" initiative. Objectives: This article aimed to discuss the "fit-for-purpose" of these tools to address budget concerns and support China in reaching her health outcomes goals. Methods: The findings are informed by a panel discussion at ISPOR Asia Pacific 2014, literature review, and authors' experience. This review looks at the current developments in China and the considerations and implications for using these tools by drawing experiences from countries where they are used. Results: These tools are generally used in countries with advanced health care systems. China's health care spending is still below that of countries with advanced health care systems and below World Health Organization recommendation. Conclusions: China has not yet reached the "critical mass" necessary for the effective use of these tools. As China continues its health care reforms, increase in health care spending to balance the health needs of the population would be key.

DOI 10.1016/j.vhri.2015.06.004
2016 Thoopputra T, Pongmesa T, Newby DA, Schneider J, Li SC, 'Opportunistic Risk Screening for Type 2 Diabetes: Exploring of Application of Diabetes Risk Assessment Tool in Community Pharmacy in Australia and Thailand', Value in Health Regional Issues, 9 1-7 (2016) [C1]

© 2015 International Society for Pharmacoeconomics and Outcomes Research (ISPOR).Objective: To evaluate the feasibility of providing diabetes risk assessment at community pharmac... [more]

© 2015 International Society for Pharmacoeconomics and Outcomes Research (ISPOR).Objective: To evaluate the feasibility of providing diabetes risk assessment at community pharmacy level in Australia and Thailand from organizational aspects. Methods: The intervention study was conducted in eight community pharmacies in New South Wales, Australia, and six community pharmacies in Central Thailand. Diabetes risk assessment tools were applied to determine the risk of developing type 2 diabetes. An open-ended question was asked to solicit the willingness-to-pay value for the service. A semistructured interview was conducted with participating pharmacists to solicit the perceived facilitators and barriers in providing the service. Results: There were a total of 132 and 185 participants, with the ratio of participants in the three risk categories of low, intermediate, and high being 1:4:11 and 2:1:1.5 for Australia and Thailand, respectively. More Thai participants were willing to pay for the service (72.4% vs. 18.9%; P = 0.0001). Pharmacists from both countries agreed that providing risk assessment would increase health awareness and assist in dampening the burden of disease. A major barrier is time and staff shortage. Support from the government and collaboration among health care providers were major facilitators from Thai pharmacists' perspective, whereas remuneration was a major facilitator from Australian pharmacists' perspective. Conclusions: Pharmacists in both countries agreed that this intervention would contribute to produce positive health benefits. Differences in advantages and barriers as well as in the proportion of consumers willing to pay for the service demonstrated that it is essential for pharmacists (particularly in developing countries) to be aware of the pitfalls of copying practice initiatives in developed countries without any consideration of the local health care environment.

DOI 10.1016/j.vhri.2015.03.022
Citations Scopus - 1
Co-authors David Newby, Jennifer Schneider
2016 Li SC, Yang Y, Zhang F, 'Analysis on the utilization status of essential medicines in Beijing¿s community health institutions.¿', Therapeutic Innovation & Regulatory Science, 1-6 (2016)
DOI 10.1177/2168479016656028
2016 Hu H, Luan L, Yang K, Li SC, 'Psychometric validation of Chinese Health Assessment Questionnaire for use in rheumatoid arthritis patients in China', International Journal of Rheumatic Diseases, (2016)

© 2016 Asia Pacific League of Associations for Rheumatology and Wiley Publishing Asia Pty Ltd.Background: To validate the psychometric properties of the Chinese Health Assessment... [more]

© 2016 Asia Pacific League of Associations for Rheumatology and Wiley Publishing Asia Pty Ltd.Background: To validate the psychometric properties of the Chinese Health Assessment Questionnaire (HAQ) for use in rheumatoid arthritis (RA) patients in China. Methods: The psychometric properties of the HAQ were validated by interviewing subjects with a questionnaire battery containing the HAQ, EQ-5D, and Short Form 12 (SF-12). Reliability was assessed by Cronbach's alpha, construct validity by assessing a priori hypotheses, and discriminative validity by discriminating subjects in different groups, respectively. To assess the applicability of HAQ in different regions, subgroup analyses were conducted for south and north China, respectively. Results: Questionnaires were administered to a consecutive sample of 133 RA patients. Cronbach's alpha showed a strong reliability among all the items. In particular, the internal reliability was higher when excluding the items about the use of aids and devices: 0.987 when excluding versus 0.963 when including. Construct validity was supported by achieving both of the a priori hypotheses based on correlations between the HAQ scores and scales of EQ-5D and SF-12. Overall, HAQ scores were important inferential factors for Global Functional Status in RA, which indicated good discriminative validity. The validation results are generally consistent between subgroups from north and south China. Conclusions: The Chinese HAQ demonstrated good acceptability and psychometric properties in RA patients from China. Two possible improvements for better use and interpretation of the patient-reported outcomes of RA patients in China could be to cross-culturally adapt the items about the use of aids and devices and joint use of mental health measurements together with HAQ in future studies.

DOI 10.1111/1756-185X.12831
2016 Zhang F, Yang Y, Huang T, Zhang Y, Zhao L, Li S, 'Is there a difference between EQ-5D and SF-6D in the clinical setting? a comparative study on the quality of life measured by AIMS2-SF, EQ-5D and SF-6D scales for osteoarthritis patients', International Journal of Rheumatic Diseases, (2016)

© 2016 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.Background: The use of both generic and disease-specific instruments in assessing... [more]

© 2016 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.Background: The use of both generic and disease-specific instruments in assessing quality of life (QoL) in subjects may pose a barrier in a busy clinical setting with heavy case load. Our current study attempted to evaluate the responsiveness of generic scales, EQ-5D and SF-6D, as compared with a disease-specific instrument, AIM2-SF, in patients with osteoarthritis, to judge which of the two generic instruments would be more suitable to be used alone in the clinical setting. Methods: Correlation tests with Pearson correlation coefficient were carried out between EQ-5D and SF-6D scales, and AIMS2-SF scale for both 100 first-diagnosed osteoarthritis patients and 22 patients with two follow-up interviews. Multivariate stepwise regression analysis was further performed on the impact of dimensions that affect the change of QoL. Results: In the evaluation of QoL for 100 patients with osteoarthritis by the EQ-5D scale, anxiety was the dimension with the highest sensitivity; while the SF-6D scale had higher sensitivity on two dimensions of psychological health and role limitations. Therefore, SF-6D would appear more suitable for evaluating QoL of arthritis patients at first presentation. For patients at follow-up interviews, EQ-5D scale maintained the highest sensitivity on anxiety and SF-6D scale only had high sensitivity on the psychological health dimension. As such, the two scales would have equivalent effects for the patients at follow-up interviews. In comparison, all the dimensions of SF-6D showed significant correlation with practically every dimension of AIMS2-SF. Hence, the overall results indicate SF-6D may be more suitable for use in patients with clinical osteoarthritis.

DOI 10.1111/1756-185X.12907
2016 Gao L, Li S, 'Emerging drugs for partial-onset epilepsy: a review of brivaracetam', THERAPEUTICS AND CLINICAL RISK MANAGEMENT, 12 719-734 (2016) [C1]
DOI 10.2147/TCRM.S90127
Citations Scopus - 2
2015 Li C-Y, Tahir NAM, Li S-C, 'A Systematic Review of Integrated Traditional Chinese and Western Medicine for Managing Irritable Bowel Syndrome', AMERICAN JOURNAL OF CHINESE MEDICINE, 43 385-406 (2015) [C1]
DOI 10.1142/S0192415X15500251
Citations Scopus - 3Web of Science - 3
2015 Gao L, Xia L, Pan S-Q, Xiong T, Li S-C, 'Burden of epilepsy: A prevalence-based cost of illness study of direct, indirect and intangible costs for epilepsy', EPILEPSY RESEARCH, 110 146-156 (2015) [C1]
DOI 10.1016/j.eplepsyres.2014.12.001
Citations Scopus - 7Web of Science - 7
2015 Li C-Y, Li S-C, 'Treatment of irritable bowel syndrome in China: A review', WORLD JOURNAL OF GASTROENTEROLOGY, 21 2315-2322 (2015) [C1]
DOI 10.3748/wjg.v21.i8.2315
Citations Scopus - 5Web of Science - 3
2015 Ren S, Newby D, Li SC, Walkom E, Miller P, Hure A, Attia J, 'Effect of the adult pneumococcal polysaccharide vaccine on cardiovascular disease: a systematic review and meta-analysis.', Open Heart, 2 1-9 (2015) [C1]
DOI 10.1136/openhrt-2015-000247
Co-authors David Newby, John Attia, Emily Walkom, Alexis Hure
2015 Gao L, Zhao FL, Li SC, 'Efficacy and Safety of Thrombin-Receptor Antagonist (Atopaxar and Vorapaxar) in Patients with Acute Coronary Syndrome or Coronary Artery Disease-A Meta-Analysis of Randomized Controlled Trials', Value in Health Regional Issues, 6 22-32 (2015)

© 2015 International Society for Pharmacoeconomics and Outcomes Research (ISPOR).Background: Meta-analysis for the efficacy and safety data of thrombin-receptor antagonist (TRA) ... [more]

© 2015 International Society for Pharmacoeconomics and Outcomes Research (ISPOR).Background: Meta-analysis for the efficacy and safety data of thrombin-receptor antagonist (TRA) based on patients with acute coronary syndrome (ACS) or coronary artery disease (CAD) and indirect comparisons between TRAs were not available. Objectives: We intended to synthesize the primary end points based on different patient populations (ACS or CAD) as well as perform indirect comparison between two newly invented antiplatelet agents atopaxar and vorapaxar. Methods: A literature search was performed in MEDLINE, Embase, and Cochrane Library. Incidences of major adverse cardiovascular events (MACEs) and bleeding events according to thrombolysis in myocardial infarction were selected as primary outcomes, whereas adverse effects were considered as secondary outcomes. Corresponding results were synthesized using Revman 5.1 according to ACS or CAD cohorts. Results: Among the seven included randomized controlled trials, the efficacy end points in the TRA treatment group were favorable compared with placebo. Specifically, the odds ratio (OR) of MACEs was 0.80 (95% confidence interval [CI] 0.52-1.22) for patients with ACS and 0.74 (95% CI 0.53-1.05) for the cohort with CAD. The events of bleeding were unanimously superior in the placebo arm for both cohorts. The indirect comparison showed a superior trend in favor of atopaxar over vorapaxar in occurrences of MACEs (OR 0.93; 95% CI 0.38-1.32), myocardial infarction (OR 0.52; 95% CI 0.13-0.95), and cardiovascular death (OR 0.82; 95% CI 0.12-4.24) and caused less incidence of bleeding. Conclusions: Besides being more effective than placebo in improving the incidence of MACEs but with a higher risk of bleeding, TRAs may exert different effects in patients with ACS and CAD. Indirect comparisons also suggested that atopaxar might be better than vorapaxar in lowering the incidence of MACEs, myocardial infarction, and cardiovascular death and at the same time with lower risks of bleeding.

DOI 10.1016/j.vhri.2015.01.003
2015 Hu H, Luan L, Li SC, 'How Quality of Life as Patient-Reported Outcome Has Been Studied for Rheumatoid Arthritis in Chinese-Speaking Population', Value in Health Regional Issues, 6 98-102 (2015)

© 2015 International Society for Pharmacoeconomics and Outcomes Research (ISPOR).Objective: To review the use of health-related quality-of-life (HRQOL) instruments as patient-rep... [more]

© 2015 International Society for Pharmacoeconomics and Outcomes Research (ISPOR).Objective: To review the use of health-related quality-of-life (HRQOL) instruments as patient-reported outcome in patients with rheumatoid arthritis (RA) in studies that have been published in Chinese-speaking populations. Methods: Overlapping searching strategy was used using four publication databases: PubMed and EMBASE for English publications and Wanfang and CNKI for Chinese publications. Entries published between January 1, 1990, and July 31, 2014, were retrieved and then reviewed independently by two researchers. The identified studies were summarized according to information source, publishing year, study location, and study type. The validation studies were examined closely in terms of their sample sizes and psychometric properties. Results: There were 99 studies from the databases selected for review. Among the studies reviewed, most studies were conducted in Mainland China. There was a clear overall increasing trend in the number of studies in recent years. Generic instruments were more frequently used by researchers outside China. Another observation was that most instruments were used without previous validation either in any Chinese-speaking population with RA or in the specific country that it was used. Conclusions: The importance of patient-reported quality of life as an outcome indicator in patients with RA is more and more realized in Chinese-speaking regions during the past two decades. To facilitate the use of HRQOL for better management of patients, and improve the quality of research, there is a strong need of validating the HRQOL instruments in more locations with a larger population, more comprehensive validity, and potential cross-cultural validation in future.

DOI 10.1016/j.vhri.2015.03.001
2015 Mohd-Tahir N-A, Paraidathathu T, Li S-C, 'Quality use of medicine in a developing economy: Measures to overcome challenges in the Malaysian healthcare system.', SAGE Open Med, 3 2050312115596864 (2015)
DOI 10.1177/2050312115596864
2015 Tahir NAM, Thomas P, Li SC, 'Challenges and opportunities in integrating complementary and alternative medicine into mainstream of the Malaysian healthcare system', TANG [HUMANITAS MEDICINE], 5 23.1-23.6 (2015)
DOI 10.5667/tang.2015.0014
2015 Li S, Thooputra T, Schneider J, Newby D, 'A Survey of the utilization of diabetes risk assessment tool (AUSDRISK) in Disease Management: A pilot study in Australia.', Thai Bulletin of Pharmaceutical Sciences, 10 1-13 (2015)
Co-authors Jennifer Schneider, David Newby
2015 Gao L, Xia L, Pan SQ, Xiong T, Li SC, 'Health-Related Quality of Life and Willingness to Pay per Quality-Adjusted Life-Year Threshold-A Study in Patients with Epilepsy in China', Value in Health Regional Issues, 6 89-97 (2015) [C1]

© 2015 International Society for Pharmacoeconomics and Outcomes Research (ISPOR).Objectives: To assess the health-related quality of life (HRQOL) and willingness to pay (WTP) per... [more]

© 2015 International Society for Pharmacoeconomics and Outcomes Research (ISPOR).Objectives: To assess the health-related quality of life (HRQOL) and willingness to pay (WTP) per quality-adjusted life-year (QALY) amount of patients with epilepsy in China. Methods: Adults with epilepsy and a healthy control were recruited in two tertiary hospitals in China. Participants completed two indirect utility elicitation instruments (Quality of Well-being Scale-self administered version and EuroQol five-dimensional questionnaire) and a WTP questionnaire. Correlations between sociodemographic or epilepsy-specific variables (age of epilepsy onset, duration of epilepsy, seizure types, types of antiepileptic drug treatment, etc.) and HRQOL or WTP/QALY were assessed to identify the candidate predictor. Multiple linear regression models were adopted to investigate the predictive performances of identified candidate predictors. Data analyses were performed on SPSS 20.0 (SPSS, Inc., Chicago, IL). Results: For utilities of both the Quality of Well-being Scale-self administered version and the EuroQol five-dimensional questionnaire, patients with epilepsy had statistically lower values than did the control group (P < 0.0001). In terms of the WTP/month, the percentage of WTP accounting for the monthly income and the WTP/QALY values from the epilepsy group were substantially higher than those from the control group (P < 0.0001).WTP/QALY=12×WTPMonth1-Utility(CurrentHealth)The multiple linear regression model identified working status (P = 0.05), seizure types (P = 0.022), income (P = 0.006), and self-rating health state (P < 0.05) as predictors of HRQOL while income (P = 0.000) and self-rating health state (P < 0.05) statistically contributed to the variations in WTP/QALY value for the epilepsy group. Conclusions: Patients with epilepsy had substantially lower HRQOL than did the healthy population.

DOI 10.1016/j.vhri.2015.03.019
2015 Chunyan L, Schneider J, Munro I, Li S, 'Introduction of flipped classroom model for learning in pharmacokinetics at the University of Newcastle, Australia', Chinese Journal of Medical Education, 35 312-315 (2015) [C1]
DOI 10.3760/cma.j.issn.1673-677X.2015.02.048
Co-authors Jennifer Schneider
2014 Gao L, Xia L, Pan SQ, Xiong T, Li SC, 'Reliability and validity of QOLIE-10 in measuring health-related quality of life (HRQoL) in Chinese epilepsy patients', Epilepsy Research, 108 565-575 (2014)

Accepted procedures were adopted to translate the QOLIE-10. Patients with epilepsy from two tertiary hospitals in China were asked to complete a standardized questionnaire includi... [more]

Accepted procedures were adopted to translate the QOLIE-10. Patients with epilepsy from two tertiary hospitals in China were asked to complete a standardized questionnaire including QOLIE-10, EQ-5D, QWB-SA and Mini Mental State Examination (MMSE). Construct validity was assessed via factor analysis. Convergent validity was explored via the correlations between QOLIE-10 and other external measures. The ability of QOLIE-10 to differentiate between epilepsy-specific variables was tested to examine the discriminant validity. Cronbach's alpha was calculated to test the reliability. Additionally, HRQoL according to different epilepsy-specific variables was compared. Results: 220 Respondents completed QOLIE-10 and EQ-5D, among which 141 subjects completed QWB-SA and MMSE. Two subscales were yielded in the factor analysis. The correlations between QOLIE-10 scores and EQ-5D, QWB-SA, MMSE were significant thus demonstrated the convergent validity. Furthermore, QOLIE-10 was able to differentiate patients with various seizure frequency, refractory epilepsy and antiepileptic treatment. The Cronbach's alpha was 0.853. In general, more predictive variables were identified to associate with QOLIE-10 scores than the other two instruments. Comorbidity (0.015), numbers of AEDs (0.037), seizure types (0.041) and refractory epilepsy (0.016) were potential predictors of HRQoLQOLIE-10, whereas there were fewer predictors for HRQoLEQ-5D or HRQoLQWB-SA.. Conclusions: QOLIE-10 appeared to be a reliable and sensitive instrument to assess the HRQoL for epilepsy patients. According to the MLR analyses, numbers of AEDs, refractory epilepsy, comorbidity depression, and cognitive function were demonstrated to be predictors of HRQoL dependent on different tools. Comparisons between the tools suggested epilepsy-specific instrument was more competent to discriminate HRQoL based on condition variables. However, a longitudinal study is still needed to examine the responsiveness of Chinese QOLIE-10. © 2014 Elsevier B.V.

DOI 10.1016/j.eplepsyres.2014.01.007
2014 Gao L, Xia L, Pan S-Q, Xiong T, Li S-C, 'Reliability and validity of QOLIE-10 in measuring health-related quality of life (HRQoL) in Chinese epilepsy patients', Epilepsy Research, (2014) [C1]

Objectives: We aimed to translate and validate a short-form of Quality of Life Inventory in Epilepsy-89 (QOLIE-89)-QOLIE-10 for use in the busy clinical setting. Methods: Accepted... [more]

Objectives: We aimed to translate and validate a short-form of Quality of Life Inventory in Epilepsy-89 (QOLIE-89)-QOLIE-10 for use in the busy clinical setting. Methods: Accepted procedures were adopted to translate the QOLIE-10. Patients with epilepsy from two tertiary hospitals in China were asked to complete a standardized questionnaire including QOLIE-10, EQ-5D, QWB-SA and Mini Mental State Examination (MMSE). Construct validity was assessed via factor analysis. Convergent validity was explored via the correlations between QOLIE-10 and other external measures. The ability of QOLIE-10 to differentiate between epilepsy-specific variables was tested to examine the discriminant validity. Cronbach's alpha was calculated to test the reliability. Additionally, HRQoL according to different epilepsy-specific variables was compared. Results: 220 Respondents completed QOLIE-10 and EQ-5D, among which 141 subjects completed QWB-SA and MMSE. Two subscales were yielded in the factor analysis. The correlations between QOLIE-10 scores and EQ-5D, QWB-SA, MMSE were significant thus demonstrated the convergent validity. Furthermore, QOLIE-10 was able to differentiate patients with various seizure frequency, refractory epilepsy and antiepileptic treatment. The Cronbach's alpha was 0.853. In general, more predictive variables were identified to associate with QOLIE-10 scores than the other two instruments. Comorbidity (0.015), numbers of AEDs (0.037), seizure types (0.041) and refractory epilepsy (0.016) were potential predictors of HRQoL, whereas there were fewer predictors for HRQoL or HRQoL. Conclusions: QOLIE-10 appeared to be a reliable and sensitive instrument to assess the HRQoL for epilepsy patients. According to the MLR analyses, numbers of AEDs, refractory epilepsy, comorbidity depression, and cognitive function were demonstrated to be predictors of HRQoL dependent on different tools. Comparisons between the tools suggested epilepsy-specific instrument was more competent to discriminate HRQoL based on condition variables. However, a longitudinal study is still needed to examine the responsiveness of Chinese QOLIE-10. © 2014 Elsevier B.V. All rights reserved.

DOI 10.1016/j.eplepsyres.2014.01.007
2014 Gao L, Li SC, Xia L, Pan S, Velakoulis D, Walterfang M, 'Validation of the Chinese version of the NUCOG cognitive screening tool in patients with epilepsy, dementia and other neurological disorders', Journal of Clinical Neuroscience, 21 980-987 (2014) [C1]

We aimed to develop and validate a Chinese version of the Neuropsychiatry Unit Cognitive Assessment Tool (NUCOG) for use in Chinese-speaking subjects internationally. Patients and... [more]

We aimed to develop and validate a Chinese version of the Neuropsychiatry Unit Cognitive Assessment Tool (NUCOG) for use in Chinese-speaking subjects internationally. Patients and healthy controls were recruited from two hospitals between July and October 2012. Receiver operating characteristic (ROC) curves were utilized to test criterion validity. Convergent validity was assessed via correlations between NUCOG and the Mini-Mental State Examination (MMSE). Reliability was measured by internal consistency (Cronbach's a). Patients with epilepsy (n = 144), neurological diseases (n = 81), dementia (n = 44), and controls (n = 260) completed the NUCOG and the MMSE. Overall, both NUCOG and MMSE scores differed significantly across the four groups with the highest scores in the control group and the lowest in the dementia group (p < 0.0001). The NUCOG scores could differentiate between patients with certain seizure types, stroke and transient ischemic attack. Compared to the MMSE, the NUCOG exhibited a higher area under the ROC curve. The convergent validity was substantially correlated, and internal consistency was very high (0.922). The Chinese version of NUCOG was demonstrated to be a sensitive and reliable screening tool for cognitive impairment in a Chinese-speaking population not only in China, but also in countries where there is a sizeable population of ethnic Chinese. Additionally, our study also showed the NUCOG could better differentiate cognitive function in patients with certain seizure types, stroke and transient ischemic attack than the MMSE. This potentially expands the clinical usefulness of NUCOG, enabling clinicians to measure the cognitive profile of patients with epilepsy and ischemic cerebrovascular diseases. © 2013 Elsevier Ltd. All rights reserved.

DOI 10.1016/j.jocn.2013.09.020
Citations Scopus - 2Web of Science - 2
2014 Gao L, Xia L, Pan S-Q, Xiong T, Li S-C, 'Psychometric properties of Chinese language Liverpool Seizure Severity Scale 2.0 (LSSS 2.0) and status and determinants of seizure severity for patients with epilepsy in China', EPILEPSY & BEHAVIOR, 31 187-193 (2014) [C1]
DOI 10.1016/j.yebeh.2013.12.011
Citations Scopus - 2Web of Science - 1
2013 Gao L, Xia L, Pan S-Q, Xiong T, Li S-C, 'Validation of a Chinese version of the Quality of Well-Being Scale-Self-Administered (QWB-SA) in patients with epilepsy', EPILEPSIA, 54 1647-1657 (2013) [C1]
DOI 10.1111/epi.12324
Citations Scopus - 4Web of Science - 3
2013 Zhao F-L, Xie F, Hu H, Li S-C, 'Transferability of Indirect Cost of Chronic Disease: A Systematic Review and Meta-Analysis', PHARMACOECONOMICS, 31 501-508 (2013)
DOI 10.1007/s40273-013-0053-6
Citations Scopus - 7Web of Science - 6
2013 Gao L, Xia L, Zhao F-L, Li S-C, 'Clinical efficacy and safety of the newer antiepileptic drugs as adjunctive treatment in adults with refractory partial-onset epilepsy: A meta-analysis of randomized placebo-controlled trials', EPILEPSY RESEARCH, 103 31-44 (2013) [C1]
DOI 10.1016/j.eplepsyres.2012.06.005
Citations Scopus - 17Web of Science - 16
2013 Zhou HJ, Dan YY, Naidoo N, Li SC, Yeoh KG, 'A Cost-Effectiveness Analysis Evaluating Endoscopic Surveillance for Gastric Cancer for Populations with Low to Intermediate Risk', PLOS ONE, 8 (2013)
DOI 10.1371/journal.pone.0083959
Citations Scopus - 5Web of Science - 4
2013 Zhao YJ, Tan LCS, Au WL, Heng DMK, Soh IAL, Li SC, et al., 'Estimating the lifetime economic burden of Parkinson's disease in Singapore', EUROPEAN JOURNAL OF NEUROLOGY, 20 368-374 (2013) [C1]
DOI 10.1111/j.1468-1331.2012.03868.x
Citations Scopus - 4Web of Science - 3
2013 Zhou HJ, Li SC, Naidoo N, Zhu F, Yeoh KG, 'Empirical evidence of the continuing improvement in cost efficiency of an endoscopic surveillance programme for gastric cancer in Singapore from 2004 to 2010', BMC HEALTH SERVICES RESEARCH, 13 (2013) [C1]
DOI 10.1186/1472-6963-13-139
Citations Scopus - 2Web of Science - 2
2013 Zhang F, Xie J, Zhang Y, Kong L, Li S, '"What Is Important During the Selection of Traditional Chinese Medicine (TCM) in a Health Care Reimbursement or Insurance System?" Critical Issues of Assessment from the Perspective of TCM Practitioners', Value in Health Regional Issues, 2 141-146 (2013) [C1]
DOI 10.1016/j.vhri.2013.01.004
2013 Zhao F, Gao L, Li S, 'Burden of Disease Studies in the Asia-Pacific Region: Are There Enough being Performed to Provide Information for Evidence-Based Health Policy?', Value in Health Regional Issues, 2 152-159 (2013) [C1]
DOI 10.1016/j.vhri.2013.02.007
Citations Scopus - 3
2012 Tu H-AT, Rozenbaum MH, Coyte PC, Li SC, Woerdenbag HJ, Postma MJ, 'Health economics of rotavirus immunization in Vietnam: Potentials for favorable cost-effectiveness in developing countries', Vaccine, 30 1521-1528 (2012) [C1]
Citations Scopus - 12Web of Science - 9
2012 Gao L, Zhao F, Li SC, 'Cost-utility analysis of liraglutide versus glimepiride as add-on to metformin in type 2 diabetes patients in China', International Journal of Technology Assessment in Health Care, 28 436-444 (2012) [C1]
Citations Scopus - 12Web of Science - 12
2012 Gao L, Zhao F, Li SC, 'Statin is a reasonable treatment option for patients with polycystic ovary syndrome: A meta-analysis of randomized controlled trials', Experimental and Clinical Endocrinology and Diabetes, 120 367-375 (2012) [C1]
Citations Scopus - 23Web of Science - 16
2012 Zhang F, Kong L-L, Zhang Y-Y, Li SC, 'Evaluation of impact on health-related quality of life and cost effectiveness of traditional chinese medicine: A systematic review of randomized clinical trials', Journal of Alternative and Complementary Medicine, 18 1108-1120 (2012) [C1]
Citations Scopus - 8Web of Science - 6
2012 Zhang X-H, Li SC, Xie F, Lo N-N, Yang K-Y, Yeo S-J, et al., 'An exploratory study of response shift in health-related quality of life and utility assessment among patients with osteoarthritis undergoing total knee replacement surgery in a tertiary hospital in Singapore', Value in Health, 15 S72-S78 (2012) [C1]
Citations Scopus - 6Web of Science - 6
2012 Zhou HJ, So JBY, Yong WP, Luo N, Zhu F, Naidoo N, et al., 'Validation of the functional assessment of cancer therapy-gastric module for the Chinese population', Health and Quality of Life Outcomes, 10 1-8 (2012) [C1]
Citations Scopus - 12Web of Science - 12
2012 Thoopputra T, Newby DA, Schneider JJ, Li SC, 'Survey of diabetes risk assessment tools: Concepts, structure and performance', Diabetes/Metabolism Research and Reviews, 28 485-498 (2012) [C1]
Citations Scopus - 11Web of Science - 8
Co-authors David Newby, Jennifer Schneider
2012 Zhang X-H, Tan K, Tan H-H, Thumboo J, Li SC, 'Are English and Chinese versions of the audit of diabetes-dependent quality of life equivalent? An exploratory study based on the universalist approach', Value in Health Regional Issues, 1 75-81 (2012) [C1]
Citations Scopus - 2
2012 Tu HAT, Woerdenbag HJ, Riewpaiboon A, Kane S, Le DM, Postma MJ, Li SC, 'Cost of illness of chronic hepatitis B infection in Vietnam', Value in Health Regional Issues, 1 23-28 (2012) [C1]
Citations Scopus - 5
2012 Tu HAT, De Vries R, Woerdenbag HJ, Li SC, Le HH, Van Hulst M, Postma MJ, 'Cost-effectiveness analysis of hepatitis B immunization in Vietnam: Application of cost-effectiveness affordability curves in health care decision making', Value in Health Regional Issues, 1 7-14 (2012) [C1]
Citations Scopus - 4
2011 Tu H-AT, Woerdenbag HJ, Kane S, Rozenbaum MH, Li SC, Postma MJ, 'Economic evaluations of rotavirus immunization for developing countries: A review of the literature', Expert Review of Vaccines, 10 1037-1051 (2011) [C1]
DOI 10.1586/erv.11.65
Citations Scopus - 20Web of Science - 15
2011 Xie F, Ye H, Zhang Y, Liu X, Lei T, Li SC, 'Extension from inpatients to outpatients: Validity and reliability of the Oxford Knee Score in measuring health outcomes in patients with knee osteoarthritis', International Journal of Rheumatic Diseases, 14 206-210 (2011) [C1]
DOI 10.1111/j.1756-185X.2010.01580.x
Citations Scopus - 10Web of Science - 8
2011 Zhao F, Yue M, Yang H, Wang TA, Wu J-H, Li SC, 'Willingness to pay per quality-adjusted life year: Is one threshold enough for decision-making? Results from a study in patients with chronic prostatitis', Medical Care, 49 267-272 (2011) [C1]
Citations Scopus - 29Web of Science - 19
2011 Zhao YJ, Tan LCS, Li SC, Au WL, Seah SH, Lau PN, et al., 'Economic burden of Parkinson's disease in Singapore', European Journal of Neurology, 18 519-526 (2011) [C1]
DOI 10.1111/j.1468-1331.2010.03210.x
Citations Scopus - 16Web of Science - 15
2011 Zhao YJ, Wee HL, Au WL, Seah SH, Luo N, Li SC, Tan LCS, 'Selegiline use is associated with a slower progression in early Parkinson's disease as evaluated by Hoehn and Yahr stage transition times (vol 17, pg 194, 2011)', PARKINSONISM & RELATED DISORDERS, 17 299-300 (2011) [C3]
DOI 10.1016/j.parkreldis.2011.02.015
Citations Scopus - 1Web of Science - 1
2011 Zhao YJ, Wee HL, Au WL, Seah SH, Luo N, Li SC, Tan LCS, 'Selegiline use is associated with a slower progression in early Parkinson's disease as evaluated by Hoehn and Yahr Stage transition times', Parkinsonism and Related Disorders, 17 194-197 (2011) [C1]
DOI 10.1016/j.parkreldis.2010.11.010
Citations Scopus - 7Web of Science - 8
2011 Li SC, Aggarwal SK, 'Estimation of resource utilisation difference between lithium and valproate treatment groups from the VALID study', Journal of Medical Economics, 14 350-356 (2011) [C1]
Citations Scopus - 3
2010 Zhao YJ, Wee HL, Chan YH, Seah SH, Au WL, Lau PN, et al., 'Progression of Parkinson's disease as evaluated by Hoehn and Yahr stage transition times.', Movement disorders : official journal of the Movement Disorder Society, 25 702-708 (2010)

This study was carried out to evaluate progression in Parkinson's disease (PD) by analyzing time taken to transit from one Hoehn and Yahr (H&Y) stage to the next stage and to inve... [more]

This study was carried out to evaluate progression in Parkinson's disease (PD) by analyzing time taken to transit from one Hoehn and Yahr (H&Y) stage to the next stage and to investigate the variables that would be associated with H&Y transition times using a large PD database that contained prospectively collected information. Data were obtained from the movement disorder database of the National Neuroscience Institute in Singapore. Kaplan-Meier (KM) survival analysis was adopted to investigate the time taken to progress through various H&Y stages. Cox regression analysis was used to examine the association between the baseline variables at the entry point of each H&Y stage and the progression to the next stage. A total of 695 patients (mean age: 65.2, male: 57.3%) were studied. Using KM analysis, the median time taken to transit from H&Y stage 1 to 2, 2 to 2.5, 2.5 to 3 were 20, 62, and 25 months, respectively; whereas the median time taken to progress from stage 3 to 4 and 4 to 5 were 24 and 26 months, respectively. Cox regression analysis revealed that older age-at-diagnosis, longer PD duration, and higher Unified Parkinson's Disease Rating Scale (UPDRS) motor scores at baseline were associated with a significantly faster progression through various H&Y stages. Gender and ethnicity were not associated with disease progression. In conclusion, H&Y transition time is a useful measure of disease progression in PD and may be utilized in clinical studies evaluating therapeutic interventions and prognostic factors in PD. 2010 Movement Disorder Society

Citations Scopus - 2
2010 Ong SC, Lim SG, Li SC, 'Reliability and validity of a Chinese version's health-related quality of life questionnaire for Hepatitis B patients', Value in Health, 13 324-327 (2010) [C1]
DOI 10.1111/j.1524-4733.2009.00615.x
Citations Scopus - 2Web of Science - 2
2010 Luo N, Wee H-L, Cheung Y-B, Feeny D, Fong K-Y, Li S-C, et al., 'Estimating a Multi-Attribute Utility Function for the Health Utilities Index Mark 3 System Based on the Preferences of Singaporeans', QUALITY OF LIFE RESEARCH, 19 21-21 (2010)
2010 Zhao YJ, Wee HL, Chan Y-H, Seah SH, Au WL, Lau PN, et al., 'Progression of Parkinson's Disease as evaluated by Hoehn and Yahr stage Transition times', Movement Disorders, 25 710-716 (2010) [C1]
DOI 10.1002/mds.22875
Citations Scopus - 38Web of Science - 35
2010 Zhao F, Yue M, Yang H, Wang T, Wu J-H, Li SC, 'Health-related quality of life in Chinese patients with chronic prostatitis/chronic pelvic pain syndrome', Quality of Life Research, 19 1273-1283 (2010) [C1]
DOI 10.1007/s11136-010-9697-2
Citations Web of Science - 8
2010 Koh Y, Yap CW, Li SC, 'Development of a combined system for identification and classification of adverse drug reactions: Alerts Based on ADR Causality and Severity (ABACUS)', Journal of the American Medical Informatics Association, 17 720-722 (2010) [C2]
Citations Scopus - 4Web of Science - 3
2010 Shi LZ, Hodges M, Drummond M, Ahn J, Li SC, Hu S, et al., 'Good research practices for measuring drug costs in cost-effectiveness analyses: An international perspective: The ISPOR Drug Cost Task Force Report-Part VI', Value in Health, 13 28-33 (2010) [C1]
DOI 10.1111/j.1524-4733.2009.00662.x
Citations Scopus - 11Web of Science - 10
2010 Soon SS, Goh SY, Bee YM, Poon JL, Li SC, Thumboo J, Wee HL, 'Audit of diabetes-dependent quality of life (ADDQoL) Chinese version for Singapore questionnaire: Reliability and validity among Singaporeans with type 2 diabetes mellitus', Applied Health Economics and Health Policy, 8 239-249 (2010) [C1]
DOI 10.2165/11313920-000000000-00000
Citations Scopus - 16
2009 Ong SC, Lim SG, Li SC, 'How big is the financial burden of hepatitis B to society? A cost-of-illness study of hepatitis B infection in Singapore', Journal of Viral Hepatitis, 16 53-63 (2009) [C1]
DOI 10.1111/j.1365-2893.2008.01042.x
Citations Scopus - 18Web of Science - 17
2009 Zhang X-H, Wee H-L, Tan K, Thumboo J, Li SC, 'Is diabetes knowledge associated with health-related quality of life among English-speaking subjects with diabetes in Singapore', Journal of Chinese Clinical Medicine, 4 144-150 (2009) [C2]
Citations Scopus - 2
2009 Luo N, Tan LCS, Zhao Y, Lau P-N, Au W-L, Li SC, 'Determination of the longitudinal validity and minimally important difference of the 8-item Parkinson's Disease Questionnaire (PDQ-8)', Movement Disorders, 24 183-187 (2009) [C1]
DOI 10.1002/mds.22240
Citations Scopus - 9Web of Science - 9
2009 Yong C, Fisher DA, Sklar GE, Li SC, 'A cost analysis of Outpatient Parenteral Antibiotic Therapy (OPAT): An Asian perspective', International Journal of Antimicrobial Agents, 33 46-51 (2009) [C1]
DOI 10.1016/j.ijantimicag.2008.07.016
Citations Scopus - 19Web of Science - 17
2009 Zhang X-H, Li SC, Fong K-Y, Thumboo J, 'The Impact of Health Literacy on Health-Related Quality of Life (HRQoL) and utility assessment among patients with rheumatic diseases', Value in Health, 12 S106-S109 (2009) [C1]
DOI 10.1111/j.1524-4733.2009.00640.x
Citations Scopus - 18Web of Science - 13
Co-authors Xu Zhang
2009 Pongmesa T, Li SC, Wee H-L, 'A survey of knowledge on diabetes in the Central Region of Thailand', Value in Health, 12 S110-S113 (2009) [C1]
DOI 10.1111/j.1524-4733.2009.00641.x
Citations Scopus - 3Web of Science - 1
2009 Zhang X-H, Jin J, Ngorsuraches S, Li SC, 'Development and validation of a scale to measure patients' trust in pharmacists in Singapore', Patient Preference and Adherence, 3 1-7 (2009) [C1]
DOI 10.1016/S1098-3015(10)64496-8
2009 Zhang X-H, Thumboo J, Fong K-Y, Li SC, 'Development and validation of a Functional Health Literacy Test', The Patient: Patient-Centred Outcomes Research, 2 169-178 (2009) [C1]
DOI 10.2165/11314850-000000000-00000
Citations Scopus - 2Web of Science - 2
2009 Ong SC, Lim SG, Li SC, 'Cultural adaptation and validation of a questionnaire for use in hepatitis B patients', Journal of Viral Hepatitis, 16 272-278 (2009) [C1]
DOI 10.1111/j.1365-2893.2009.01073.x
Citations Scopus - 2Web of Science - 2
2008 Zhang X-H, Xie F, Wee H-L, Thumboo J, Li SC, 'Applying the expectancy-value model to understand health values', Value in Health, 11 S61-S68 (2008) [C1]
DOI 10.1111/j.1524-4733.2008.00368.x
Citations Scopus - 6Web of Science - 5
2008 Xie F, Thumboo J, Fong K-Y, Lo N-N, Yeo S-J, Yang K-Y, Li SC, 'A study on indirect and intangible costs for patients with knee osteoarthritis in Singapore', Value in Health, 11 S84-S90 (2008) [C1]
DOI 10.1111/j.1524-4733.2008.00371.x
Citations Scopus - 16Web of Science - 12
2008 Wee H-L, Li SC, Xie F, Zhang X-H, Luo N, Feeny D, et al., 'Validity, feasibility and acceptability of time trade-off and standard gamble assessments in health valuation studies: A study in a multiethnic Asian population in Singapore', Value in Health, 11 S3-S10 (2008) [C1]
DOI 10.1111/j.1524-4733.2008.00361.x
Citations Scopus - 12Web of Science - 9
2008 Wee H-L, Cheung Y-B, Loke W-C, Tan C-B, Chow M-H, Li SC, et al., 'The association of body mass index with health-related quality of life: An exploratory study in a multiethnic Asian population', Value in Health, 11 S105-S114 (2008) [C1]
DOI 10.1111/j.1524-4733.2008.00374.x
Citations Scopus - 30Web of Science - 18
2008 Tarn TYH, Hu SL, Kamae I, Yang BM, Li SC, Tangcharoensathien V, et al., 'Health-care systems and pharmacoeconomic research in Asia-Pacific region', Value in Health, 11 S137-S155 (2008) [C1]
DOI 10.1111/j.1524-4733.2008.00378.x
Citations Scopus - 37Web of Science - 20
2008 Jin J, Sklar GE, Oh VMS, Li SC, 'Factors affecting therapeutic compliance: A review of from the patient's perspective', Therapeutics and Clinical Risk Management, 4 269-286 (2008) [C1]
Citations Scopus - 253
2008 Wee H-L, Li SC, Zhang X-H, Xie F, Feeny D, Luo N, et al., 'Are symbols useful and culturally acceptable in health-state valuation studies? An exploratory study in a multi-ethnic Asian population', Patient Preference and Adherence, 2 271-276 (2008) [C1]
DOI 10.2147/PPA.S4142
2008 Zhao YJ, Tan LCS, Lau PN, Au WL, Li SC, Luo N, 'Factors affecting health-related quality of life amongst Asian patients with Parkinson's disease', European Journal of Neurology, 15 737-742 (2008) [C1]
DOI 10.1111/j.1468-1331.2008.02178.x
Citations Scopus - 32Web of Science - 31
2008 Li SC, 'Can pharmacoeconomic guidelines be implemented successfully in Asia?', Journal of Medical Economics, 11 341-343 (2008) [C3]
DOI 10.3111/13696990802221171
Citations Scopus - 1
2008 Lee KKC, Li SC, Kwong KS, Chan TYK, Lee VWY, Lau JTF, 'A study of the health and economic effects of influenza-like illness on the working population under different working environments of a large corporation in Hong Kong', Journal of Medical Economics, 11 639-650 (2008) [C1]
DOI 10.3111/13696990802533179
Citations Scopus - 1
2008 Koh Y, Yap CW, Li SC, 'A quantitative approach of using genetic algorithm in designing a probability scoring system of an adverse drug reaction assessment system', International Journal of Medical Informatics, 77 421-430 (2008) [C1]
DOI 10.1016/j.ijmedinf.2007.08.010
Citations Scopus - 20Web of Science - 16
2008 Ngorsuraches S, Lerkiatbundit S, Li SC, Sirithorn R, Korwiwattanakarn M, 'Development and Validation of Patient's Trust Scale in Community Pharmacist (Trust-Ph)', Research in Social and Administrative Pharmacy, 4 272-283 (2008) [C1]
DOI 10.1016/j.sapharm.2007.10.002
Citations Scopus - 9Web of Science - 8
2008 Li SC, Piggott C, 'A focus group study of barriers for female community pharmacists providing counselling for male sexual dysfunction', NSW Pharmacist, 15-16 (2008) [C3]
2008 Ong SC, Mak B, Aung MO, Li SC, Lim S-G, 'Health-related quality of life in chronic hepatitis B patients', Hepatology, 47 1108-1117 (2008) [C1]
DOI 10.1002/hep.22138
Citations Scopus - 56Web of Science - 52
2008 Xie F, Lo NN, Lee HP, Cieza A, Li SC, 'Validation of the international classification of functioning, disability, and health (ICF) brief core set for osteoarthritis', Scandinavian Journal of Rheumatology, 37 450-461 (2008) [C1]
DOI 10.1080/03009740802116216
Citations Scopus - 9Web of Science - 8
2008 Xie F, Li SC, Goeree R, Tarride J-E, O'Reilly D, Lo N-N, et al., 'Validation of Chinese Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) in patients scheduled for total knee replacement', Quality of Life Research, 17 595-601 (2008) [C1]
DOI 10.1007/s11136-008-9340-7
Citations Scopus - 33Web of Science - 28
2008 Luo N, Seng B-K, Xie F, Li SC, Thumboo J, 'Psychometric evaluation of the Schizophrenia Quality of Life Scale (SQLS) in English- and Chinese-speaking Asians in Singapore', Quality of Life Research, 17 115-122 (2008) [C1]
DOI 10.1007/s11136-007-9278-1
Citations Scopus - 4Web of Science - 4
2007 Wee H-L, Li SC, 'Sociodemographic factors influencing the effectiveness of public health education: A comparison of two studies in Singapore', Annals Academy of Medicine Singapore, 36 958-961 (2007) [C1]
2007 Wee HL, Loke WC, Li SC, Fong KY, Cheung YB, Machin D, et al., 'Cross-cultural adaptation and validation of Singaporean Malay and Tamil versions of the EQ-5D', Annals of the Academy of Medicine Singapore, 36 403-408 (2007) [C1]
Citations Scopus - 12Web of Science - 12
2007 Xie F, Thumboo J, Fong K-Y, Lo N-N, Yeo S-J, Yang K-Y, Li S-C, 'Direct and indirect costs of OA in Singapore: A comparative study among multiethnic Asian patients', JOURNAL OF RHEUMATOLOGY, 34 165-171 (2007)
Citations Scopus - 21Web of Science - 17
2007 Xie F, Lo NN, Lee HP, Cieza A, Li SC, 'Validation of the comprehensive ICF core set for Osteoarthritis (OA) in patients with knee OA: A Singaporean perspective', Journal of Rheumatology, 34 2301-2307 (2007) [C1]
Citations Scopus - 8Web of Science - 8
2007 Xie F, Thumboo J, Li SC, 'Direct and Indirect Costs of Osteoarthritis: A Perspective from Multiethnic Asian Patients with Osteoarthritis in Singapore', Journal of Rheumatology, 34 165-171 (2007) [C1]
2007 Xie F, Li S-C, Lo N-N, Yeo S-J, Yang K-Y, Yeo W, et al., 'Cross-cultural adaptation and validation of Singapore English and Chinese Versions of the Oxford Knee Score (OKS) in knee osteoarthritis patients undergoing total knee replacement', OSTEOARTHRITIS AND CARTILAGE, 15 1019-1024 (2007)
DOI 10.1016/j.joca.2007.02.013
Citations Scopus - 33Web of Science - 30
2007 Xie F, Thumboo J, Lo NN, Yeo SJ, Yang KY, Yeo W, et al., 'Cross-Cultural Adaptation and Validation of Singapore English and Chinese Versions of the Lequesne Algofunctional Index of Knee in Asians with Knee Osteoarthritis in Singapore.', Osteoarthritis and Cartilage, 15 19-26 (2007) [C1]
DOI 10.1016/j.joca.2006.06.013
Citations Scopus - 15Web of Science - 11
2007 Zhang XH, Li SC, Xie F, Lo NN, Yang KY, Yeo SJ, Thomboo J, 'Investigation of response shift in health-related quality of life among patients undergoing total knee replacement', VALUE IN HEALTH, 10 A253-A253 (2007)
DOI 10.1016/S1098-3015(10)64947-9
2007 Wee HL, Machin D, Loke WC, Cheung YB, Li SC, Luo N, et al., 'Assessing Systematic Differences in Utility Scores: A comparison of four widely used preference-based instruments', Value in Health, 10 256-265 (2007) [C1]
DOI 10.1111/j.1524-4733.2007.00174.x
Citations Scopus - 29Web of Science - 24
2007 Li SC, 'How to improve pharmacoeconomic data generalisability between different countries', Expert Opinion on Pharmacotherapy, 8 1409-1413 (2007) [C3]
Citations Scopus - 1Web of Science - 2
2007 Wee HL, Ravens-Sieberer U, Erhart M, Li SC, 'Factor structure of the Singapore English version of the KINDL (R) children quality of life questionnaire', Health and Quality of Life Outcomes, 5 (2007) [C1]
DOI 10.1186/1477-7525-5-4
Citations Scopus - 20Web of Science - 14
2007 Li SC, 'Health care system and public sector drug formulary in Singapore', ISPOR Connections, 13 4-7 (2007) [C2]
2007 Xie F, Li SC, Luo N, Lo NN, Yeo SJ, Yang KY, et al., 'Comparison of the EuroQol and short form 6D in Singapore multiethnic Asian knee osteoarthritis patients scheduled for total knee replacement', Arthritis and Rheumatism, 57 1043-1049 (2007) [C1]
DOI 10.1002/art.22883
Citations Scopus - 29Web of Science - 28
2007 Xie F, Thumboo J, Li SC, 'True Difference or Something Else? Problems in Cost of Osteoarthritis Studies', Seminars in Arthritis and Rheumatism, 37 127-132 (2007) [C1]
DOI 10.1016/j.semarthrit.2007.01.001
Citations Scopus - 21Web of Science - 19
2007 Luo N, Wang Q, Feeny D, Chen G, Li SC, Thumboo J, 'Measuring health preferences for health utilities index mark 3 health states: A study of feasibility and preference differences among ethnic groups in Singapore', Medical Decision Making, 27 61-70 (2007) [C1]
DOI 10.1177/0272989x06297103
Citations Scopus - 6Web of Science - 6
2006 Li SC, Ong SC, Lim SG, 'Health related quality of life in chronic hepatitis B patients', VALUE IN HEALTH, 9 A308-A308 (2006)
DOI 10.1016/S1098-3015(10)63531-0
2006 Zhang XH, Ngorsuraches S, Li SC, 'Development and Validation of a scale to measure patients trust in pharmacists', Value in Health, 9 (2006) [C1]
2006 Chong LY, Chay OM, Li SC, 'Is the Childhood Asthma Questionnaire (CAQ) a good measure of Health-related Quality of Life (HRQoL) of Asthmatic Children in Asia? Validation of Childhood Asthma Questionnaire (CAQ B) Among Asthma Pediatric Patients in Singapore', PharmacoEconomics, 24 609-621 (2006) [C1]
DOI 10.2165/00019053-200624060-00007
Citations Scopus - 5Web of Science - 2
2006 Wee HL, Tan CE, Goh SY, Li SC, 'Usefulness of the Audit of Diabetes-Dependent Quality-of-Life (ADDQOL) Questionnaire Patients with Diabetes in a multi-ethnic Asian country', PharmacoEconomics, 24 673-682 (2006) [C1]
DOI 10.2165/00019053-200624070-00006
Citations Scopus - 47Web of Science - 37
2006 Wee HL, Chua HX, Li SC, 'Meaning of Health-related Quality-of-Life among children and adolescents in an Asian country: A focus group approach', Quality of Life Research, 15 821-831 (2006) [C1]
DOI 10.1007/s11136-005-5092-9
Citations Scopus - 17Web of Science - 11
2006 Luo N, Seng BK, Thumboo J, Feeney D, Li SC, 'A Study of the Construct Validity of the Health Utilities Index Mark 3 (HUI3) in Patients with Schizophrenia', Quality of Life Research, 15 889-898 (2006) [C1]
DOI 10.1007/s11136-005-5745-8
Citations Scopus - 6Web of Science - 5
2006 Wee HL, Li SC, Xie F, Zhang XH, Luo N, Cheung YB, et al., 'Are Asians comfortable with discussing death in health valuation studies? A qualitative study in multi-ethnic Singapore.', Health and Quality of Life Outcomes, 4 93-93 (2006) [C1]
DOI 10.1186/1477-7525-4-93
Citations Scopus - 2Web of Science - 2
2006 Zhang XH, Xie F, Wee HL, Thumboo J, Li SC, 'Applying the Expectancy-Value Model to understand Health Preference An Exploratory Study.', Value in Health, 9 (3) (2006) [C3]
2006 Wee HL, Li SC, Cheung YB, Fong YH, Thumboo J, 'The Influence of ethnicity on Health-related Quality of Life in Diabetes Mellitus: A Population-based Multi-Ethnic Study.', Journal of Diabetes and Its Complications, 20 170-178 (2006) [C1]
DOI 10.1016/j.jdiacomp.2005.06.010
Citations Scopus - 28Web of Science - 26
2006 Xie F, Li SC, Roos E, Lo NN, Yeo SJ, Yang KY, et al., 'Cross-Cultural Adaptation and Validation of Singapore English and Chinese Versions of the Knee Injury and Osteoarthritis Outcome Score (KOOS) in Asians with Knee Osteoarthritis in Singapore', Osteoarthritis and Cartilage, 14 1098-1103 (2006) [C1]
DOI 10.1016/j.joca.2006.05.005
Citations Scopus - 36Web of Science - 35
2006 Xie F, Li SC, Fong KY, Yeo SJ, Yang KY, Thumboo J, 'What Health Domains & Items Are Important to Patients with Knee Osteoarthritis? A Focus Group Study in a Multi-Ethnic Asian Population in Singapore', Osteoarthritis and Cartilage, 14 224-230 (2006) [C1]
DOI 10.1016/j.joca.2005.09.009
Citations Scopus - 22Web of Science - 22
2006 Ngorsuraches S, Li SC, 'Thai Pharmacists'' Understanding, Attitudes, and Perceived Barriers Related to the Provision of Pharmaceutical Care', American Journal of Health-System Pharmacy, 63 2144-2150 (2006) [C1]
DOI 10.2146/ajhp060054
Citations Scopus - 20Web of Science - 12
2006 Xie F, Thumboo J, Fong KY, Lo NN, Yeo SJ, Yang KY, Li SC, 'Are They Relevant? A Critical Evaluation of the International Classification of Functioning, Disability and Health Core Sets for Osteoarthritis from the Perspective of Patients with Knee Osteoarthritis in Singapore', Annals of the Rheumatic Diseases, 65 1067-1076 (2006) [C1]
DOI 10.1136/ard.2005.043067
2005 Koh Y, Li SC, 'A New Algorithm to Identify the Causality of Adverse Drug Reactions: Development of Algorithm', Drug Safety 2005, 28 1159-1161 (2005) [C3]
Citations Scopus - 13Web of Science - 14
2005 Xie F, Thumboo J, Li SC, 'Are they Relevant? A Critical Evaluation of the International Classification of Functioning, Disability and Health Core Sets for Osteoarthritis from the Perspective of Patients with Knee Osteoarthritis in Singapore', Annals of the Rheumatic Diseases, 8 1067-1073 (2005) [C1]
Citations Scopus - 12Web of Science - 12
2005 Chui WK, Li SC, 'Advice giving on self-medication by community pharmacists in Singapore', Journal of Clinical Pharmacy and Therapeutics, 30 225-231 (2005) [C1]
DOI 10.1111/j.1365-2710.2005.00637.x
Citations Scopus - 15Web of Science - 9
2005 Hing WC, Yeoh TT, Yeoh SF, Lin R, Li SC, 'An evaluation of antimicrobial prophylaxis in paediatric surgery and its financial implication', Journal of Clinical Pharmacy and Therapeutics, 30 371-381 (2005) [C1]
DOI 10.1111/j.1365-2710.2005.00659.x
Citations Scopus - 11Web of Science - 11
2005 Xie F, Tan CH, Li SC, 'Are They Used Safely? A Study on Prescribing Pattern of Selective Serotonin Reuptake Inhibitors in Singapore', Human Psychopharmacology, 20 459-465 (2005) [C1]
DOI 10.1002/hup.711
Citations Scopus - 3Web of Science - 3
2005 Luo N, Tan LC, Li SC, Soh LK, Thumboo J, 'Validity and Reliability of the Chinese (Singapore) Version of the Parkinson''s Disease Questionnaire (PDQ-39).', Quality of Life Research, 14 273-279 (2005) [C3]
Citations Scopus - 16Web of Science - 10
2005 Wee HL, Lee WW, Ravens-Sieberer U, Erhart M, Li SC, 'Validation of the English Version of the KINDL Generic Children''s Health-related Quality of Life Instrument for an Asian Population - Results from a Pilot Test', Quality of Life Research, 14 1193-1200 (2005) [C3]
Citations Scopus - 29Web of Science - 29
2005 Xie F, Luo N, Li SC, 'The European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire (EORTC QLQ-C30): Validation of English version in Singapore', Quality of Life Research, 14 1181-1186 (2005) [C3]
Citations Scopus - 39Web of Science - 32
2005 Zhang XH, Wee HL, Tan K, Tan K, Tan HH, Tan HH, et al., 'An Exploratory Study of the Equivalence between the English and Chinese Versions of the Audit of Diabetes-Dependent Quality of Life (ADDQOL) based on the Universalist Approach.', Quality of Life Research, 14 (2005) [C3]
2005 Xie F, Thumboo J, Fong KY, Lo NN, Yeo SJ, Yang KY, Li SC, 'Are they relevant? A critical evaluation of the international classification of functioning, disability and health core sets for osteoarthritis from the perspective of patients with knee osteoarthritis in Singapore', VALUE IN HEALTH, 8 A27-A27 (2005)
DOI 10.1016/S1098-3015(10)67219-1
2005 Ong SC, Lim SG, Li SC, 'Validation of a Health-related Quality of Life Instrument for Hepatitis B patients in Singapore', Value in Health, 8 312-312 (2005) [C1]
2005 Zhang XH, Wee HL, Tan K, Tan HH, Thumboo J, Li SC, 'Is Diabetes Knowledge Associated with Health-related Quality of Life among English-speaking Subjects with Diabetes in Singapore?', Value in Health, 8 365-366 (2005) [C1]
2005 Koh Y, Fatimah MK, Li SC, 'Drug related problems in hospitalized patients on polypharmacy: The influence of age and gender', Therapeutics and Clinical Risk Management, 1 39-48 (2005) [C1]
2005 Wee HL, Cheung YB, Fong KY, Li SC, Thumboo J, 'The Impact of Diabetes and other Chronic Medical Conditions on Health-related Quality of Life: Is the Whole Greater than the Sum of its Parts?', Health and Quality of Life Outcomes, 3 1-2 (2005) [C1]
DOI 10.1186/1477-7525-3-2
Citations Scopus - 77
2005 Lau TC, Lau TC, Lim BP, Lim BP, Li SC, 'Cost-Effectiveness Analysis of Bisphosphonates and Raloxifene for Treatment of Osteoporosis and Prevention of Fractures.', Value in Health, 8 (3) (2005) [C3]
2005 Xie F, Li SC, Thumboo J, 'Do the Important Health-Related Quality of Life Domains & Items in Knee & Hip Osteoarthritis Vary in Importance Across Social-Cultural Contexts? A Qualitative Systematic Literature Review', Seminars in Arthritis and Rheumatism, 34 793-804 (2005) [C1]
DOI 10.1016/j.semarthrit.2005.02.003
Citations Scopus - 15Web of Science - 15
2004 Li SC, Ong SC, Lim SG, Yeoh KG, Kwong KS, Lee V, et al., 'A cost comparison of management of chronic hepatitis B and its associated complications in Hong Kong and Singapore.', Journal of clinical gastroenterology, 38 (2004)

GOALS: To estimate and compare the direct medical cost in the management of chronic hepatitis B (CHB) infection and its complications from the perspective of public health organiz... [more]

GOALS: To estimate and compare the direct medical cost in the management of chronic hepatitis B (CHB) infection and its complications from the perspective of public health organizations in Hong Kong and Singapore. BACKGROUND: Hong Kong and Singapore are endemic hepatitis B virus areas with about 10% and 5%, respectively, of the population estimated as hepatitis B virus infected. STUDY: The medical histories of 660 patients with CHB who received medical services over 5 years from three major public hospitals in Hong Kong and Singapore were studied retrospectively. Costs were analyzed according to the five disease states and estimated in Hong Kong dollars (HKD) and Singapore dollars (SGD). RESULTS: In both Hong Kong and Singapore, the per-patient total annual cost increased with the severity of the disease. CHB cost HKD 6318 (US 810 dollars) in Hong Kong and SGD 718.15 (US 410.37 dollars) in Singapore. Compensated cirrhosis cost HKD 10,304 (US 1321 dollars) in Hong Kong and SGD 1,175.34 (US 671.62 dollars) in Singapore. Decompensated cirrhosis cost HKD 58,428 (US 7490 dollars) in Hong Kong and SGD 15,389.84 (US 8794.19 dollars) in Singapore. Hepatocellular carcinoma cost HKD 121,822 (US 15,618 dollars) in Hong Kong and SGD 12314.04 (US 7036.59 dollars) in Singapore. Each case of liver transplant was estimated to cost HKD 514,498 (US 65,961 dollars) in Hong Kong and SGD 86,369.28 (US 49,353.87 dollars) in Singapore. CHB in Hong Kong accounted for about 4% of the healthcare expenditure. CONCLUSION: This study confirms that CHB and its liver disease complications are a significant economic burden to the healthcare budgets of Hong Kong and Singapore, and indicates that effective therapy that arrests or reverses the progression of liver disease would be highly cost-effective.

Citations Scopus - 25
2004 Zhou S, Chan E, Li SC, Huang M, Chen X, Li X, et al., 'Predicting pharmacokinetic herb-drug interactions', Drug Metabolism and Drug Interactions, 20 143-158 (2004)

In vitro and in vivo studies have indicated that the induction or inhibition of cytochrome P450 (CYP) is one of the major mechanisms for some clinically important pharmacokinetic ... [more]

In vitro and in vivo studies have indicated that the induction or inhibition of cytochrome P450 (CYP) is one of the major mechanisms for some clinically important pharmacokinetic herb-drug interactions. Thus, an attempt was made to predict pharmacokinetic herb-drug interactions using the pharmacokinetic principles that are used for predicting drug-drug interactions. The expected AUC ratio was mainly dependent on unbound herbal inhibitor concentration ([I]) and inhibition constant (Ki), hepatic fraction (fh), number of inhibitory herbal constituents (n) and metabolic pathway fraction in hepatic metabolism (fm). Herb-drug interactions would be with low risk if ¿ i=1n [[I i]/Ki(i)] is less than 0.1, medium risk if it is between 0.1 and 1.0, and high risk if it is greater than 1. For high clearance drugs, the change of fh × fm had minor influence on AUC ratio when ¿i=1n [[Ii]/Ki(i)] values were fixed. Similarly, fm did not affect the AUC ratio for low clearance drugs. It appeared likely to predict a herb-drug metabolic interaction when [I], Ki, fh, fm and n could be determined. However, many herb- and drug-related factors may cause difficulties with the prediction, and well-designed human studies are always necessary.

Citations Scopus - 24
2004 Tsai WL, Chang HM, Hwu Y, Hsu PC, Tsai HI, Chow GM, et al., 'Imaging cells with refractive index radiology', Biophysical Journal, 87 4180-4187 (2004) [C1]
DOI 10.1529/biophysj.103.034991
Citations Scopus - 42
2004 Li SC, Ong SC, Lim SG, Yeoh KG, Kwong SKS, Lee V, et al., 'A Cost Comparison of Management of Chronic Hepatitis B and its Associated Complications in Hong Kong and Singapore', Journal of Clinical Gastroenterology, 38 S136-S143 (2004) [C1]
DOI 10.1097/00004836-200411003-00004
Citations Web of Science - 21
2004 Hing WC, Bek SJ, Lin R, Li SC, 'Retrospective Drug Utilisation of Vancomycin in a paediatric hospital', Journal of Clinical Pharmacy and Therapeutics, 29 359-365 (2004) [C1]
DOI 10.1111/j.1365-2710.2004.00571.x
Citations Scopus - 12Web of Science - 8
2004 Luo N, Koh Y, Tan CH, Kua EH, Li SC, 'Drug utilization review of risperidone for outpatients from a tertiary referral hospital in Singapore', Human Psychopharmacology, 19 259-264 (2004) [C1]
DOI 10.1002/hup.585
Citations Scopus - 3Web of Science - 2
2004 Luo N, Fones CS, Thumboo J, Li SC, 'Factors influencing health-related quality of life in Asians with anxiety disorders in Singapore', Quality of Life Research, 13 557-565 (2004) [C3]
Citations Scopus - 19Web of Science - 14
2004 Wee HL, Goh SY, Li SC, Lim SG, Ong SC, Tan CE, Thumboo J, 'Is the influence of sociodemographic factors on EQ-5D scores affected by the underlying disease: A study in patients with chronic hepatitis B or diabetes mellitus.', Quality of Life Research, 13 (2004) [C3]
2004 Doherty J, Kamae I, Lee K, Li H, Li SC, Liu G, et al., 'What''s Next for Pharmacoeconomics and Outcomes Research in Asia?', Value in Health, 7 118-132 (2004) [C1]
DOI 10.1111/j.1524-4733.2004.72330.x
Citations Scopus - 28Web of Science - 18
2004 Zhou S, Chan E, Lim LY, Boelsterli UA, Li SC, Wang J, et al., 'Therapeutic drugs that behave as mechanism-based inhibitors of cytochrome P450 3A4', Current Drug Metabolism, 5 415-442 (2004) [C1]
DOI 10.2174/1389200043335450
Citations Scopus - 133Web of Science - 107
2004 Gao F, Luo N, Thumboo J, Fones CS, Li SC, Cheung YB, 'Does the 12-item General Health Questionnaire contain multiple factors and do we need them?', Health and Quality of Life Outcomes, 2 63-63 (2004) [C1]
DOI 10.1186/1477-7525-2-63
Citations Scopus - 63
2004 Koh Y, Fatimah HK, Fatimah MK, Li SC, 'Prevalence of drug-related problems amongst hospitalised patients on polypharmacy in Singapore.', Value in Health, 7 (3) (2004) [C1]
2003 Koh DR, Ng SC, Yoon KH, Vasoo S, Li SC, Thumboo J, et al., 'Do English and Chinese EQ-5D versions demonstrate measurement equivalence? An exploratory study', Health and Quality of Life Outcomes, 1 1-7 (2003) [C1]
DOI 10.1186/1477-7525-1-7
Citations Scopus - 42
2003 Chong LY, Chay OM, Li SC, 'Cultural adaptation and validation of Childhood Asthma Questionnaire-C (CAQ-C) in Singapore', Value in Health, 6(3) 374-375 (2003) [C3]
2003 Wee HL, Li SC, 'Reliability and validity of KINDL children generic health-related quality of life questionnaire in an Asian school-based sample.', Value in Health, 6(3) (2003) [C3]
2003 Luo N, Seng BK, Li SC, Thumboo J, 'Health-related quality of life in outpatients with schizophrenia in Singapore', Value in Health, 6 (6) 695-695 (2003) [C3]
2003 Luo N, Tan LCS, Li SC, Thumboo J, 'Validation of Singaporean English and Chinese EQ-5D Versions in Patients with Parkinsons Disease', Value in Health, 6 (6) 769-769 (2003) [C3]
2003 Li SC, 'An introduction to pharmacoeconomic evaluation in rheumatology', International Journal of Rheumatic Diseases, 6 192-200 (2003) [C1]
DOI 10.1046/j.0219-0494.2003.00046.x
2003 Luo N, Seng BK, Li SC, 'Identification of factors influencing caregiving experience in caregivers of patients with schizophrenia.', Annals of the Academy of Medicine, Singapore, 32 (2003)
Citations Scopus - 1
2003 Luo N, Seng BK, Li SC, 'Identification of factors influencing caregiving experience in caregivers of patients with schizophrenia', Annals of the Academy of Medicine Singapore, 32 43-45 (2003) [C1]
2003 Luo N, Fong KH, Koh DR, Ng SC, Yoon KH, Vascoo S, et al., 'Validity and Reliability of the EQ-5D Self-Report Questionnaire in Chinese-Speaking Patients with Rheumatic Diseases in Singapore', Annals of the Academy of Medicine Singapore, 32 685-690 (2003) [C1]
Citations Scopus - 59Web of Science - 49
2003 Luo N, Chew LH, Fong KY, Koh DR, Ng SC, Yoon KH, et al., 'A comparison of the EQ-5D and the health utilities index mark 3 (HUI3) in patients with rheumatic diseases', Journal of Rheumatology, 30 2268-2274 (2003) [C1]
Citations Scopus - 45Web of Science - 38
2003 Koh Y, Fatimah MK, Li SC, 'Therapy related hospital admission in patients on polypharmacy in Singapore: a pilot study', Pharmacy World and Science: international journal of clinical pharmacy and pharmaceutical care, 25 135-137 (2003) [C1]
DOI 10.1023/A:1024896328720
Citations Scopus - 14Web of Science - 12
2003 Luo N, Li SC, Seng BK, Thumboo J, 'Construct Validity of the Health Utilities Index Mark 3 (HUI3) in Patients with Schizophrenia.', Qual Life Res, 7 (2003) [C1]
2003 Luo N, Li SC, Seng BK, Thumboo J, 'Responsiveness of the Schizophrenia Quality of Life Scale (SQLS) and the Short Form 36 Health Survey (SF-36) in patients with Schizophrenia: A comparative Study.', Qual Life Res, 7 (2003) [C3]
2003 Luo N, Fong KH, Koh DR, Ng SC, Yoon KH, Vascoo S, et al., 'Validity and Reliability of the ED-5D Self-Report Questionnaire in English-speaking Asian Patients with Rheumatic Diseases in Singapore', Quality of Life Research, 12 87-92 (2003) [C3]
Citations Scopus - 67Web of Science - 58
2002 Tan LC, Luo N, Nazri M, Li SC, Thumboo J, 'Validity and Reliability of the PDQ-39 and the PDQ-8 in English-speaking Parkinson''s Disease Patients in Singapore', Parkinsonism and Related Disorders, 10 493-499 (2002) [C1]
Citations Scopus - 34Web of Science - 31
2002 Qeuk JT, Li SC, 'A Study of the effectiveness of AIDS health education interventions among the adolescent population of Singapore.', Singapore Medical Journal, 43 279-283 (2002) [C1]
2002 Wee WL, Ho HK, Li SC, 'Public awareness of diabetes mellitus in Singapore.', Singapore Medical Journal, 43 128-134 (2002) [C1]
Citations Scopus - 54
2002 Quek JT, Li SC, 'A Study of the Effectiveness of AIDS Health Education Interventions among the Adolescent Population of Singapore', Singapore Medical Journal, 43 359-364 (2002)

Aim of study: This study aims to evaluate the effectiveness of existing AIDS health education interventions in Singapore amongst the adolescent population of Singapore. By identif... [more]

Aim of study: This study aims to evaluate the effectiveness of existing AIDS health education interventions in Singapore amongst the adolescent population of Singapore. By identifying specific target groups that lack knowledge and information regarding HIV, it is hoped that suggestions may be provided towards increasing the effectiveness of these interventions. Method: A cross-sectional survey using a self-administered questionnaire of randomly selected adolescents between the ages of 13 and 19 years was performed to assess their knowledge of HIV and their opinions and awareness of HIV education in Singapore. Results: A total of 400 adolescents of various backgrounds were surveyed. In general, the subjects surveyed possessed reasonably good knowledge about HIV/AIDS, with an average score of 77.4% (SD =15.8%). However, the results also showed areas of knowledge deficiency and misconception prevalent among those surveyed. Subgroup analysis showed that adolescents from low-income families, relatively less academically successful schools and those of younger ages knew significantly less than other adolescents. In terms of the awareness of HIV/AIDS education and information, the percentage of the subjects who could recognise any of the three commonly issued pamphlets or poster or who knew of any telephone numbers to call to receive information on HIV and AIDS was low. Less than 40% of those surveyed felt that enough awareness was being created within the public regarding AIDS. Conclusion: It can be concluded that most adolescents surveyed felt that they are inadequately educated regarding HIV and AIDS. The results would suggest the need for focusing more efforts on certain target groups using the appropriate media in future educational intervention.

Citations Scopus - 8
2002 Wee HL, Lee WW, Li SC, 'Psychometric evaluation of a generic HRQOL instrument (KID-KINDL) for self-assessment of HRQOL in Singaporean children with diabetes: A pilot study', Diab Res Clin Pract, 56(1) (2002) [C1]
2002 Luo N, Chew LH, Koh DR, Ng SC, Yoon KH, Vascoo S, et al., 'Are Singaporean English and Chinese EQ-5D Versions psychometrically equivalent? An Exploratory Study', Quality of Life Research, 11 (2002) [C1]
2002 Luo N, Chew LH, Koh DR, Ng SC, Yoon KH, Vascoo S, et al., 'Comparing the EQ-5D and Health Utilities Index (HUI-3) in Subjects with Rheumatic Diseases.', Quality of Life Research, 11 (2002) [C1]
2002 Chong LY, Chay OM, Goh A, Seng YC, Li SC, 'Cultural adaptation and validation of Childhood Asthma Questionnaire Version B (CAQ-B) For Singapore Children.', Val Health, 5 (3) (2002) [C1]
2001 Luo N, Leng S, Fongs C, Li SC, 'Validation of the medical outcomes study short-form 36 health survey (SF-36) for quality-of-life assessment of Chinese patients with anxiety disorders in Singapore', Quality of Life Res, 9 (2001) [C1]
2001 Wee HL, Lee WR, Li SC, 'Evaluation of a generic quality-of-life instrument (KINDL) for self-assessment of QOL in Singaporean children with diabetes: a pilot study.', Val Health, 0 510-510 (2001) [C3]
2001 Roy AN, Li SC, 'A Survey of Public Hospital Pharmacists in Singapore on their Views about The Formulary and its Decision-making Process.', Value in Health, 4 (2) (2001) [C1]
1996 Wood PJ, IoannidesDemos LL, Li SC, Williams TJ, Hickey B, Spicer WJ, et al., 'Minimisation of aminoglycoside toxicity in patients with cystic fibrosis', THORAX, 51 369-373 (1996)
DOI 10.1136/thx.51.4.369
Citations Scopus - 38Web of Science - 43
1994 MCLEAN AJ, BASTONE EB, IOANNIDESDEMOS LL, LI SC, CHRISTOPHIDIS N, SPICER WJ, 'INTERACTION OF GENTAMICIN PEAK AND TROUGH CONCENTRATIONS ON BACTERIAL KILL', CLINICAL PHARMACOLOGY & THERAPEUTICS, 55 192-192 (1994)
1994 IOANNIDESDEMOS LL, LI SC, BASTONE EB, SPELMAN DW, HOOPER RE, COUSINS VC, MCLEAN AJ, 'ABSENCE OF TOXICITY IN PATIENTS WITH MALIGNANT OTITIS-EXTERNA FOLLOWING LONG-TERM TREATMENT WITH HIGH DOSAGE TOBRAMYCIN', JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 34 267-274 (1994)
DOI 10.1093/jac/34.2.267
Citations Scopus - 8Web of Science - 9
1993 IOANNIDESDEMOS LL, LI SC, BASTONE EB, SPICER WJ, 'BACTERICIDAL EFFECTS OF GENTAMICIN PEAK CONCENTRATIONS PROVIDE A RATIONALE FOR BOLUS ADMINISTRATION', CLINICAL PHARMACOLOGY & THERAPEUTICS, 53 194-194 (1993)
1993 IOANNIDESDEMOS LL, LI SC, SPELMAN DW, HOOPER RE, COUSINS V, BASTONE EB, MCLEAN AJ, 'RATIONALE AND INITIAL EXPERIENCE OF HIGH-DOSE AMINOGLYCOSIDE THERAPY OF MALIGNANT OTITIS-EXTERNA', CLINICAL PHARMACOLOGY & THERAPEUTICS, 53 194-194 (1993)
1993 BASTONE EB, LI SC, IOANNIDESDEMOS LI, SPICER WJ, MCLEAN AJ, 'KILL KINETICS AND REGROWTH PATTERNS OF ESCHERICHIA-COLI EXPOSED TO GENTAMICIN CONCENTRATION-TIME PROFILES SIMULATING INVIVO BOLUS AND INFUSION DOSING', ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 37 914-917 (1993)
Citations Scopus - 26Web of Science - 27
1993 MCLEAN AJ, IOANNIDESDEMOS LL, LI SC, BASTONE EB, SPICER WJ, 'BACTERICIDAL EFFECT OF GENTAMICIN PEAK CONCENTRATION PROVIDES A RATIONALE FOR ADMINISTRATION OF BOLUS DOSES', JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 32 301-305 (1993)
DOI 10.1093/jac/32.2.301
Citations Scopus - 18Web of Science - 14
1992 LI SC, IOANNIDESDEMOS LL, SPICER WJ, SPELMAN DW, TONG N, MCLEAN AJ, 'PROSPECTIVE AUDIT OF AN AMINOGLYCOSIDE CONSULTATIVE SERVICE IN A GENERAL-HOSPITAL', MEDICAL JOURNAL OF AUSTRALIA, 157 308-311 (1992)
Citations Scopus - 17Web of Science - 14
1992 CORVAIA L, LI SC, IOANNIDESDEMOS LL, BOWES G, SPICER WJ, SPELMAN DW, et al., 'A PROSPECTIVE-STUDY OF THE EFFECTS OF ORAL PROBENECID ON THE PHARMACOKINETICS OF INTRAVENOUS TICARILLIN IN PATIENTS WITH CYSTIC-FIBROSIS', JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 30 875-878 (1992)
DOI 10.1093/jac/30.6.875
Citations Scopus - 7Web of Science - 4
1991 LI SC, BOWES G, IOANNIDESDEMOS LL, SPICER WJ, HOOPER RE, SPELMAN DW, et al., 'DOSAGE ADJUSTMENT AND CLINICAL OUTCOMES OF LONG-TERM USE OF HIGH-DOSE TOBRAMYCIN IN ADULT CYSTIC-FIBROSIS PATIENTS', JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 28 561-568 (1991)
DOI 10.1093/jac/28.4.561
Citations Scopus - 7Web of Science - 7
1989 LI SC, IOANNIDESDEMOS LL, SPICER WJ, BERBATIS C, SPELMAN DW, TONG N, MCLEAN AJ, 'PROSPECTIVE AUDIT OF AMINOGLYCOSIDE USAGE IN A GENERAL-HOSPITAL WITH ASSESSMENTS OF CLINICAL PROCESSES AND ADVERSE CLINICAL OUTCOMES', MEDICAL JOURNAL OF AUSTRALIA, 151 224-& (1989)
Citations Scopus - 24Web of Science - 24
1989 Li SC, Ioannides-Demos LL, Harrison PM, Spicer WJ, Spelman DW, Tong N, et al., 'Case applications of a computer-aided aminoglycoside therapeutic monitoring technique', Australian Journal of Hospital Pharmacy, 19 147-152 (1989)
Citations Scopus - 3
Show 178 more journal articles

Review (3 outputs)

Year Citation Altmetrics Link
2005 Zhang J, Tian Q, Chan SY, Duan W, Li SC, Zhu YZ, Zhou SF, 'Metabolism and Transport of Oxazaphosphorines and the Clinical Implications.', Drug Metabolism Review (2005) [D1]
Citations Scopus - 115Web of Science - 103
2004 Zhou S, Chan E, Li SC, Huang M, Li X, Zhang Q, 'Predicting pharmacokinetic herb-drug in', Drug Metabolism and Drug Interaction (2004) [D1]
2003 Li SC, 'An Overview of Community pharmacist interventions: Assessing cost-effectiveness and patients willingness to pay', Disease Management and Health Outcomes (2003) [D1]
Citations Scopus - 4Web of Science - 3

Conference (107 outputs)

Year Citation Altmetrics Link
2016 Zhang F, Li SC, Yang Y, 'ANALYSIS ON THE UTILIZATION STATUS OF ESSENTIAL MEDICINES IN BEIJING'S COMMUNITY HEALTH INSTITUTIONS', VALUE IN HEALTH (2016)
2016 Tahir MNA, Li SC, 'META-ANALYSIS OF NEWER ANTI-EPILEPTIC DRUGS FOR TREATMENT OF PARTIAL EPILEPSY IN CHILDREN', VALUE IN HEALTH (2016)
2016 Wang T, Li SC, Liu GG, Wu Z, Sun Y, 'REFORM OF CHINESE STATE-OWNED ENTERPRISE-AFFILIATED HOSPITAL', VALUE IN HEALTH (2016)
2016 Tahir MNA, Thomas P, Bakry MM, Gafor AAH, Li SC, 'COST-EFFECTIVENES OF A COMBINA TION OF RENIN-ANGIOTENSIN SYSTEM INHIBITORS (RAS)/CA LCIUM CHANEL BLOCKERS (CCB) OR RAS MONOTHERAPY TO RETARD PROGRESION OF KIDNEY DISEASE IN MALAYSIA', VALUE IN HEALTH (2016)
2016 Zhang F, Li SC, 'ANALYSIS ON THE UTILIZATION STATUS OF ESSENTIAL MEDICINES IN BEIJING'S COMMUNITY HEALTH INSTITUTIONS', VALUE IN HEALTH (2016)
2016 Li W, Yang J, Li SC, Ho CL, 'CORRELATION BETWEEN TEA CONSUMPTION AND PREVALENCE OF HYPERTENSION AMONG SINGAPOREAN CHINESE RESIDENTS OVER 40', VALUE IN HEALTH (2016)
2016 Luan L, Hu H, Li SC, 'A REVIEW OF STUDIES OF HEALTH-RELATED QUALITY OF LIFE PERFORMED IN CHINESE-SPEAKING ISCHEMIC HEART DISEASE PATIENTS', VALUE IN HEALTH (2016)
2016 Yang K, Li SC, 'A REVIEW OF TREATMENT ON ALZHEIMER'S DISEASE IN CHINA', VALUE IN HEALTH (2016)
2016 Tahir MNA, Thomas P, Bakry MM, Ali A, Li SC, 'COST-EFFECTIVENESS OF NEWER ANTIEPILEPTIC DRUGS (AEDS) FOR MANAGEMENT OF PARTIAL EPILEPSY IN CHILDREN IN MALAYSIA', VALUE IN HEALTH (2016)
2016 Tahir MNA, Thomas P, Li SC, 'BURDEN OF OSTEOPOROSIS-RELATED HIP FRACTURE IN ASIA. A REVIEW OF HEALTH CARE COSTS AND RESOURCE UTILIZATION', VALUE IN HEALTH (2016)
2016 Tahir MNA, Thomas P, Bakry MM, Said MMS, Li SC, 'COST-EFFECTIVENESS OF BISPHOSPHONATES FOR PRIMARY AND SECONDARY PREVENTION OF HIP-RELATED FRACTURE WITH GLUCOCORTICOID-INDUCED OSTEOPOROSIS IN MALAYSIA', VALUE IN HEALTH (2016)
2016 Hu H, Luan L, Yang KQ, Li SC, 'PSYCHOLOGICAL DISTRESS IN CHINESE PATIENTS WITH RHEUMATOID ARTHRITIS AND PSYCHOMETRIC VALIDATION OF CHINESE HOSPITAL ANXIETY AND DEPRESSION SCALE', VALUE IN HEALTH (2016)
2016 Zhang F, Li SC, Guan Y, 'HOT ISSUES ABOUT DRUG PRICE IN CHINA: FROM THE VIEW OF INTERNET PUBLIC OPINION MONITORING', VALUE IN HEALTH (2016)
2014 Gao L, Li SC, 'COST-EFFECTIVENESS OF TREATING ACUTE CORONARY SYNDROME PATIENTS WITH RIVAROXBAN IN AUSTRALIA', VALUE IN HEALTH (2014) [E3]
2014 Tahir MNA, Li SC, Thomas P, 'CHALENGES AND OPORTUNITIES IN THE MALAYSIAN HEALTH CARE SYSTEM', VALUE IN HEALTH (2014) [E3]
2013 Gao L, Walterfang M, Velakoulis D, Li SC, 'VALIDATION OF A CHINESE VERSION OF NEUROPSYCHIATRY UNIT COGNITIVE ASSESSMENT TOOL (NUCOG)', VALUE IN HEALTH (2013) [E3]
2012 Zhang F, Li SC, Du J, 'SATISFACTION ASSESSMENT OF INSURANCE SYSTEM FOR URBAN RESIDENTS (URMS) OF UNIVERSITY STUDENTS IN SHENYANG', VALUE IN HEALTH (2012) [E3]
2012 Zhang F, Du J, Li SC, 'Satisfaction assessment of insurance system for urban residents (URMS) of university students in Shenyang', Value in Health (2012) [E3]
2012 Gao L, Li SC, 'Cost-utility analysis of liraglutide versus glimepiride as add-on to metformin in patients with type 2 diabetes in China', Value in Health (2012) [E3]
Citations Web of Science - 1
2012 Gao L, Li SC, 'Statin is a reasonable treatment option for patients with polysystic ovary syndrome: A meta-analysis of randomized controlled trials', Value in Health (2012) [E3]
2012 Zhao F, Xie F, Li SC, 'Transferability of indirect cost of chronic disease: A systematic review and meta-analysis', Value in Health: ISPOR 15th Annual European Congress and ISPOR 5th Asia-Pacific Conference (2012) [E3]
2012 Tu HAT, Coyte P, Li SC, Postma MJ, 'Cost-effectiveness of rotavirus immunization in Vietnam: Exploring impacts of herd immunity and patterns of breastfeeding of', Value in Health: ISPOR 15th Annual European Congress and ISPOR 5th Asia-Pacific Conference (2012) [E3]
2012 Thoopputra T, Li SC, Newby DA, Schneider JJ, 'Pharmaceutical care intervention for disease management in community pharmacies in Australia', Value in Health: ISPOR 15th Annual European Congress and ISPOR 5th Asia-Pacific Conference (2012) [E3]
Co-authors David Newby, Jennifer Schneider
2012 Thoopputra T, Newby DA, Schneider JJ, Li SC, 'Awareness and perception of diabetes risk assessment in community pharmacy in Australia', Research in Social and Administrative Pharmacy: Workshop and Presentation Abstracts from the 17th International Social Pharmacy Workshop (2012) [E3]
Co-authors David Newby, Jennifer Schneider
2011 Zhang F, Li SC, Fu S, Xie J, Zhang Y, Kong L, 'What is important during the pharmacoeconomic evaluation of CAM (complementary and alternative medicine)?- A survey research', Value in Health (2011) [E3]
2011 Tu HAT, Rozenbaum M, Coyte PC, Li SC, Postma MJ, 'Cost-effectiveness of rotavirus immunization in Vietnam: Results and challenges', Value in Health (2011) [E3]
2011 Thoopputra T, Li SC, Newby DA, Schneider JJ, 'A literature review of diabetes risk assessment tools', Value in Health (2011) [E3]
Co-authors David Newby, Jennifer Schneider
2010 Xie F, Pullenayegum E, Li SC, 'USE OF A DISEASE-SPECIFIC INSTRUMENT IN ECONOMIC EVALUATIONS: MAPPING WOMAC ONTO THE EQ-5D UTILITY INDEX', VALUE IN HEALTH (2010) [E3]
DOI 10.1016/S1098-3015(10)72660-7
2010 Zhao FL, Yue M, Wu JH, Yang H, Wang T, Li SC, 'VALIDATION AND COMPARISON OF EUROQOL AND SHORT FORM 6D IN CHINESE CHRONIC PROSTATITIS PATIENTS', VALUE IN HEALTH (2010) [E3]
DOI 10.1016/S1098-3015(10)72898-9
Citations Web of Science - 1
2010 Xie F, Pullenayegum E, Li SC, 'Use of disease-specific instrument in economic evaluations: Mapping Womac into the EQ-5D utility index', Value in Health (2010) [E3]
DOI 10.1111/j.1524-4733.2010.00770.x
Citations Scopus - 25Web of Science - 21
2010 Zhao F, Yue M, Wu JH, Yang H, Wang T, Li SC, 'Validation and comparison of euroqol and short form 6D in chronic prostatitis patients', Value in Health (2010) [E3]
DOI 10.1111/j.1524-4733.2010.00728.x
Citations Scopus - 23Web of Science - 20
2010 Pongmesa T, Li SC, Wee HL, 'Development of a Thai version of The Audit of Diabetes-Dependent Quality of Life (ADDQOL-19) Questionnaire: Linguistic and psychometric evaluation', Value in Health (2010) [E3]
2010 Pongmesa T, Wee HL, Li SC, 'Health status, health-related quality of life and treatment satisfaction among patients with diabetes in Thailand', Value in Health (2010) [E3]
2010 Tu HAT, Riewpaiboon A, Woerdenbag HJ, Postma MJ, Li SC, 'Cost-of-illness of chronic hepatitis B infection in Vietnam', Value in Health (2010) [E3]
2010 Zhao F, Yue M, Yang H, Wang T, Wu JH, Li SC, 'Willingness to pay per quality adjusted life-year: Is one threshold applicable for all decision-making', Value in Health (2010) [E3]
Citations Web of Science - 2
2010 Zhao F, Yue M, Yang H, Wang T, Wu JH, Li SC, 'Health-related quality of life in Chinese chronic prostatitis patients', Value in Health (2010) [E3]
DOI 10.1007/s11136-010-9697-2
Citations Scopus - 10
2009 Zhao FL, Li SC, 'A SYSTEMATIC REVIEW OF BURDEN OF DISEASE STUDIES IN THE ASIA-PACIFIC REGION', VALUE IN HEALTH (2009) [E3]
DOI 10.1016/S1098-3015(10)73176-4
2009 Xie F, Ye H, Zhang Y, Liu X, Lei T, Li SC, 'EXTENSION FROM INPATIENTS TO OUTPATIENTS: PERFORMANCE OF THE OXFORD KNEE SCORE IN MEASURING HEALTH OUTCOMES IN PATIENTS WITH KNEE OSTEOARTHRITIS', VALUE IN HEALTH (2009) [E3]
DOI 10.1016/S1098-3015(10)73420-3
2009 Zhao YJ, Tan LC, Seah SH, Lau PN, Au WL, Li SC, et al., 'RATE OF DISEASE PROGRESSION AMONG PATIENTS WITH PARKINSON'S DISEASE IN SINGAPORE', VALUE IN HEALTH (2009) [E3]
DOI 10.1016/S1098-3015(10)74011-0
2009 Xie F, Ye H, Zhang Y, Liu X, Lei T, Li SC, 'Extension from inpatients to outpatients: Performance of the Oxford Knee Score in measuring health outcomes in patients with knee osteoarthritis', Value in Health (2009) [E3]
DOI 10.1111/j.1524-4733.2009.00537_2.x
2009 Zhao YJ, Tan LC, Seah SH, Lau PN, Au WL, Li SC, et al., 'Rate of disease progression among patients with Parkinson's disease in Singapore', Value in Health (2009) [E3]
DOI 10.1111/j.1524-4733.2009.00537_2.x
2009 Zhao F, Li SC, 'A systematic review of burden of disease studies in the Asia-Pacific region', Value in Health (2009) [E3]
DOI 10.1111/j.1524-4733.2009.00537_2.x
2009 Zhao F, Wu JH, Yue M, Li SC, 'Willingness to pay per quality-adjusted life year of chronic prostatits patients in China', Value in Health (2009) [E3]
2008 Pongmesa T, Li SC, Wee HL, 'A comparison of diabetes knowledge among residents in Bangkok and other central provinces of Thailand', Value in Health (2008) [E3]
2008 Pongmesa T, Wee HL, Li SC, 'A survey of diabetes knowledge among the general population in Thailand', ISPOR 3rd Asia-Pacific Conference. Abstracts (2008) [E3]
2008 Li SC, Nguyen T, 'Cost analysis between valproate and lithium in the management of biopolar disorder: Results from a multinational study (Vlaid study - valproate versus lithium in bipolar disorders', ISPOR 3rd Asia-Pacific Conference. Abstracts (2008) [E3]
2008 Zhao YJ, Tan LC, Lau PN, Au WL, Li SC, Luo N, 'Determination of the longitudinal validity and minimally important difference of the 8-item Parkinson's disease questionnaire (PDQ-8)', Value in Health (2008) [E3]
2007 Zhang XH, Li SC, Xie F, Lo NN, Yang KY, Yeo SJ, Thomboo J, 'Investigation of response shift in health-related quality of life among patients undergoing total knee replacement', Value in Health (2007) [E3]
DOI 10.1111/j.1524-4733.2007.00263_2.x
2007 Jin J, Sklar GE, Oh MS, Li SC, 'What factors affect compliance of hypertensive patients with their treatment?: A qualitative study', Value in Health (2007) [E3]
2007 Zhao YJ, Tan LC, Lau PN, Au WL, Li SC, Luo N, 'Identifications of Factors Affecting Quality of Life in Patients with Parkinsons Disease' (2007) [E4]
2007 Ong SC, Lim SG, Li SC, 'Cultural Adaptation and Validation of A Health-Related Quality of Life Questionnaire for English-speaking Hepatitis B patients in Singapore' (2007) [E4]
2007 Ngorsuraches S, Lerkiatbundit S, Li SC, Sirithorn R, Korwiwattanakarn M, 'Development and Validation of Patients Trust Scale in Community Pharmacist (TRUST-Ph)' (2007) [E4]
2006 Zhang XH, Xie F, Wee HL, Thumboo J, Li SC, 'Applying the Expectancy-Value Model to understand Health Preference - An Exploratory Study.', - (2006) [E1]
2006 Fong K, Lo N, Yeo S, Yang K, Li SC, Xie F, Thumboo J, 'Are they measurable? A Study on Eliciting Indirect and Intangible Costs of Knee Osteoarthritis Using Human Capital Approach and Willingness-to-Pay in Multiethnic Asian Population in Singapore.', Value in Health (2006) [E3]
DOI 10.1016/S1098-3015(10)63270-6
2006 Zhang XH, Ngorsuraches S, Li SC, 'Development and Validation of a scale to measure patients trust in pharmacists', Proceedings of the ISPOR 11th Annual International Meeting (2006) [E1]
2006 Li SC, Zhang X, Xie F, Luo N, Cheung Y, Machin D, et al., ''The Impact of Discussing Death on Health Preferences: A Pilot Study in A Multi-Ethnic Asian Population', 17th Annual EuroQol Group Plenary Meeting (2006) [E3]
2006 Ngorsuraches S, Li SC, 'Barriers to pharmaceutical care in Thailand', ISPOR 2nd Asia-Pacific Conference (2006) [E3]
2006 Koh Y, Yap C, Li SC, 'Developing a qualitative scoring system for adverse drug reaction assessment using genetic algorithm', ISPOR 2nd Asia-Pacific Conference (2006) [E3]
2006 Yap K, Su J, Li SC, Ho P, ''Nanoparticulate Delivery System of Carboplatin', Proceedings of 18th Singapore Pharmacy Congress (2006) [E3]
2006 Jin J, Li SC, 'A Review of Factors affecting Therapeutic Compliance', Proceedings of 18th Singapore Pharmacy Congress (2006) [E3]
2006 Zhang XH, Ngorsuraches S, Li SC, 'Development and Validation of a scale to measure patients trust in pharmacists', Proceedings of 18th Singapore Pharmacy Congress (2006) [E1]
Citations Scopus - 3Web of Science - 5
2006 Koh Y, Lee YM, Fatimah MK, Li SC, 'The Economic Value of Pharmacists - Participation in Physicians-Pharmacists Review Team.', Proceedings of 18th Singapore Pharmacy Congress (2006) [E3]
2006 Li SC, Iloeje U, Yuan Y, Lim S, ''A modelled economic implication of replacing lamivudine with entecavir in chronic hepatitis B (ChB) patients in Singapore.', Proceedings of 21st Annual Scientific Meeting of Singapore Society of Gastroenterologists (2006) [E3]
2006 Wee HL, Li SC, Xie F, Zhang XH, Luo N, Cheung YB, et al., 'How do survey respondents interpret and utilize symbols used in health valuation studies', Proceedings of ISPOR 2nd Asia Pacific Conference (2006) [E3]
2006 Wee HL, Li SC, Xie F, Zhang XH, Luo N, Cheung YB, et al., 'Feasibility and acceptability of TTO and SG and factors influencing their acceptance for health valuation among Singaporeans', Proceedings of ISPOR 2nd Asia Pacific Conference (2006) [E3]
2006 Wee HL, Li SC, Xie F, Zhang XH, Luo N, Cheung YB, et al., 'The impact of talking about death on health state valuation: A study among Chinese and Indian Singaporeans', Proceedings of ISPOR 2nd Asia Pacific Conference (2006) [E3]
2006 Koh Y, Lee Y, Fatimah M, Ang Y, Li SC, ''The Clinical & Economic Value of Pharmacists Participation in Physicians-Pharmacists Review Team', Proceedings of National Healthcare Group Annual Scientific Congress (2006) [E3]
2005 Lau TC, Lim BP, Li SC, 'Cost-Effectiveness Analysis of Bisphosphonates and Raloxifene for Treatment of Osteoporosis and Prevention of Fractures.', - (2005) [E1]
2005 Xie F, Thumboo J, Li SC, 'Are they Relevant? A Critical Evaluation of the International Classification of Functioning, Disability and Health Core Sets for Osteoarthritis from the Perspective of Patients with Knee Osteoarthritis in Singapore', - (2005) [E1]
2005 Guo X, Tan S, Luo N, Li SC, 'The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30): Validation of English and Chinese Versions in Singapore', Proceedings of 15th Science Research Congress (2005) [E3]
2005 Lim X, Wong L, Li SC, 'Usage of Alternative and Complementary Medicines in Singapore', Proceedings of 17th Singapore Pharmacy Congress (2005) [E3]
2005 Wee Y, Chui W, Li SC, 'A Study of Pharmacists - Understanding, Attitude. And Practice of Pharmaceutical Care in Singapore', Proceedings of 17th Singapore Pharmacy Congress & Inaugural NUS Pharmacy Intervarsity Congress (2005) [E3]
2005 Zhang XH, Wee HL, Tan K, Tan HH, Thumboo J, Li SC, 'An Exploratory Study of the Equivalence between the English and Chinese Versions of the Audit of Diabetes-Dependent Quality of Life (ADDQOL) based on the Universalist Approach.', Quality of Life Research (2005) [E1]
2005 Zhang XH, Zhang XH, Wee HL, Wee HL, Tan K, Tan K, et al., 'Is Diabetes Knowledge Associated with Health-related Quality of Life among English-speaking Subjects with Diabetes in Singapore?' (2005) [E3]
2005 Ong SC, Lim SG, Yeoh KY, Li SC, 'A Cost Analysis of Chronic Hepatitis B Infection & Its Associated Complications in Singapore' (2005) [E4]
2005 Wee HL, Zhang XH, Tan K, Tan HH, Thumboo J, Li SC, 'Reliability and Validity of the General Diabetes Knowledge Test' (2005) [E4]
2004 Li SC, 'Pharmacoeconomics: Uses in Practice and Research in Singapore' (2004) [E4]
2004 Wee HL, Goh SY, Li SC, Tan CE, Thumboo J, 'Does the generic EQ-5D function as well as disease-specific ADDQOL in persons with diabetes?' (2004) [E4]
2004 Tan CE, Thumboo J, Wee HL, Goh SY, Li SC, Lim SG, Ong SC, 'Is the influence of sociodemographic factors on EQ-5D scores affected by the underlying disease: A study in patients with cronic hepatitis B or diabetes mellitus.', Quality of Life Research 2005 (2004) [E1]
2004 Koh Y, Fatimah HK, Fatimah MK, Li SC, 'Prevalence of drug-related problems amongst hospitalised patients on polypharmacy in Singapore.' (2004) [E1]
2004 Xie F, Luo N, Li SC, 'The European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire (EORTC QLQ-C30): Validation of English version in Singapore' (2004) [E1]
2003 Keung X, Chiu W, Li SC, ''A survey of consumers on the provision of professional advice given by community pharmacists on self-medication', 16th Singapore Pharmacy Congress (2003) [E3]
2003 Ang Y, Chiu W, Li SC, 'Survey of Community Pharmacists on the Provision of Professional Advice to consumers who seeks self-medication for minor aliment management', Proceedings of 16th Singapore Pharmacy Congress (2003) [E3]
2003 Koh Y, Chan C, Li SC, ''Comparison of five established adverse drug reaction algorithms in a patient sample in Singapore', Proceedings of European Society of Clinical Pharmacy 4th Spring Conference (2003) [E3]
2003 Seng B, Luo N, Li SC, ''The psychological distress in caregivers of patients with schizophrenia in Singapore', Proceedings of the NHG Annual Scientific Congress 2003 (2003) [E3]
2003 Luo N, Li SC, Seng BK, Thumboo J, 'Construct Validity of the Health Utilities Index Mark 3 (HUI3) in Patients with Schizophrenia.', Quality of Life Research 2003 (2003) [E1]
2003 Luo N, Li SC, Seng BK, Thumboo J, 'Responsiveness of the Schizophrenia Quality of Life Scale (SQLS) and the Short Form 36 Health Survey (SF-36) in patients with Schizophrenia: a comparative study.', Quality of Life Research 2003 (2003) [E1]
2003 Luo N, Seng BK, Thumboo J, Li SC, 'Health-related quality of life in outptients with schizophrenia in Singapore.', Value in Health (2003) [E1]
2003 Wee HL, Li SC, 'Reliability and validity of KINDL children generic health related quality of life questionnaire in an Asian school based sample', Value in Health (2003) [E1]
2003 Chong LY, Chay OM, Li SC, 'Cultural adaptation and validation of Childhood Asthma Questionnaire-C', Value in health 2003 (2003) [E1]
2003 Luo N, Tan LC, Li SC, Thumboo J, 'Validation of Singaporean English and Chinese EQ-5D Versions in Patients with Parkinsons Disease', Value in health 6 (2003) [E1]
2003 Luo N, Seng BK, Thumboo J, Li SC, 'Validation of English and Chinese versions of the SQLS, the SF-36 and the HUI3 in Patients with Schizophrenia in Singapore.', Value in Health (2003) [E3]
Citations Web of Science - 1
2002 Li SC, 'A Survey on Consumers - Behaviours in the Purchase of Medicines', First Health Sciences Authority Scientific Seminar (2002) [E3]
2002 Fatimah M, Li SC, ''Pilot Study to quantify the Extent of Polypharmacy in Alexandra Hospital in the Geriatric Population', Proceedings of 15th Singapore Pharmacy Congress (2002) [E3]
2002 Koh Y, Fatimah M, Li SC, 'Prevalence of Drug Therapy Related Hospital Admission and its Association with Polypharmacy and Age of Patients in Singapore', Proceedings of 15th Singapore Pharmacy Congress (2002) [E3]
2002 Li SC, Yeoh T, Yeo S, Lin R, ''An Audit of Antimicrobial Surgical Prophylaxis in Pediatric Patients in Singapore', Proceedings of FIP 62nd International Congress (2002) [E3]
2002 Seng B, Luo N, Li SC, ''Validation of the Experience of Caregiving Inventory (ECI) and the Burden Assessment Scale (BAS) in English-speaking Caregivers of Patients with Schizophrenia in Singapore', Proceedings of the 1st Scientific Meeting of the National Healthcare Group (2002) [E3]
2002 Luo N, Seng B, Thumboo J, Li SC, 'Validation of the Schizophrenia Quality of Life Scale (SQLS) and the Short Form 36 Health Survey (SF-36) in English-speaking Patients with Schizophrenia in Singapore', Proceedings of the 1st Scientific Meeting of the National Healthcare Group (2002) [E3]
2002 Luo N, Chew LH, Koh DR, Ng SC, Yoon KH, Vascoo S, et al., 'Are Singaporean English and Chinese EQ-5D Versions psychometrically equivalent? An Exploratory Study' (2002) [E1]
2002 Chong LY, Chay OM, Goh A, Seng YC, Li SC, 'Cultural adaptation and validation of Childhood Asthma Questionnaire Version B (CAQ-B) For Singapore Children.' (2002) [E1]
2002 Wee HL, Lee WW, Li SC, 'Psychometric evaluation of a generic HRQOL instrument (KID-KINDL) for self-assessment of HRQOL in Singaporean children with diabetes: A pilot study' (2002) [E1]
2002 Vascoo S, Li SC, Thumboo J, Luo N, Chew LH, Koh DR, et al., 'Comparing the EQ-5D and Health Utilities Index (HUI-3) in Subjects with Rheumatic Diseases.' (2002) [E1]
2001 Luo N, Fones C, Li SC, 'A study of the Quality of Life in patients with anxiety disorders in Singapore', Proceedings of FIP 61st International Congress (2001) [E3]
2001 Ku H, Tan M, Li SC, 'Attitude and knowledge towards Traditional Medicine among Singaporeans', Singapore Traditional Chinese Medicine (TCM) Research Symposium 2001 (2001) [E3]
2001 Luo N, Chew LH, Fong KY, Ng SC, Yoon KH, Li SC, Thumboo J, 'Validity and Reliability of EQ-50 Domains in Asians in Singapore with Rheumatic Diseases' (2001) [E1]
2001 Roy AN, Li SC, 'A Survey of Public Hospital Pharmacists in Singapore on their Views about The Formulary and its Decision-making Process.' (2001) [E1]
2001 Luo N, Leng S, Fongs C, Li SC, 'Validation of the medical outcomes study short-form 36 health survey (SF-36) for quality-of-life assessment of Chinese patients with anxiety disorders in Singapore' (2001) [E1]
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Grants and Funding

Summary

Number of grants 1
Total funding $15,000

Click on a grant title below to expand the full details for that specific grant.


20121 grants / $15,000

NHVA PhD Research Project$15,000

Funding body: Newcastle & Hunter Valley Pharmacists Association Inc

Funding body Newcastle & Hunter Valley Pharmacists Association Inc
Project Team Professor Shu Chuen Li, Mr Hao Hu
Scheme Research Grant
Role Lead
Funding Start 2012
Funding Finish 2014
GNo G1200632
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y
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Research Supervision

Number of supervisions

Completed4
Current13

Total current UON EFTSL

PhD5.65

Current Supervision

Commenced Level of Study Research Title Program Supervisor Type
2017 PhD Developing the Screening Tool of Potentially Inappropriate Prescribing in Geriatric Patients in Vietnam PhD (Pharmacy), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2016 PhD The Economic Evaluation of Management on Alzheimer's Disease in Mainland China PhD (Pharmacy), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2014 PhD Improving Post-marketing Monitoring of Risk and Benefits of Drugs for Chronic Diseases in China PhD (Pharmacy), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2014 PhD Improvement of quality use of medicine in management of chronic respiratory diseases: The role of pharmacists PhD (Pharmacy), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2014 PhD Implementation of an Appropriate Screening Tool for Depression in Adults with Chronic Illness by Australian Community Pharmacists PhD (Clinical Pharm), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2013 PhD Quality use of Medicines in Malaysian Public Health System: The Role of Pharmacists PhD (Pharmacy), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2012 PhD Potential Cardio-Protective Effect of Pneumococcal Vaccine PhD (Clinical Pharm), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2008 PhD Pharmacovigilance and development of signal detection algorithm for drug safety monitoring PhD (Pharmacy), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2008 PhD The Cost Effective Management of Osteoporosis to Prevent Fractures in Singapore PhD(Experimental Pharmacology), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2006 PhD Pharmacoeconomic study of Parkinson's Disease in Singapore Pharmacy, Unknown Principal Supervisor
2006 PhD A comparison of the impact of pharmaceutical care in diabetic patients in Singapore and Thailand Pharmacy, Unknown Principal Supervisor
2006 Masters Impact of therapeutic compliance on clinical and economic outcomes Pharmacy, Unknown Principal Supervisor
2005 PhD Methodlogical Issues in Pharmacoeconomics and Outcomes Research Pharmacy, Unknown Principal Supervisor

Past Supervision

Year Level of Study Research Title Program Supervisor Type
2017 PhD Evidence and Value Based Healthcare Decision Making for Chronic Disease in China PhD (Pharmacy), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2015 PhD How to Implement Quality Use of Medicines in Developing Countries - An Example from China PhD (Pharmacy), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2014 PhD Risk Management for Type 2 Diabetes in Community Pharmacy Practice PhD (Pharmacy), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2011 PhD Evidence-Based Reimbursement Decision-Making in Asia-Pacific Region: Transferability of the Economic Evaluation Between Different Jurisdictions PhD(Experimental Pharmacology), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
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Professor Shu Chuen Li

Position

Professor
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine

Focus area

Pharmacy and Experimental Pharmacology

Contact Details

Email shuchuen.li@newcastle.edu.au
Phone (02) 4921 5921
Fax (02) 492 17903

Office

Room MS108
Building Medical Sciences
Location Callaghan
University Drive
Callaghan, NSW 2308
Australia
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