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Dr Lisa Lincz

Conjoint Senior Lecturer

School of Biomedical Sciences and Pharmacy (Medical Biochemistry)

Career Summary

Biography

Research Expertise
Genetic susceptibility to disease and treatment toxicity, Mechanisms of snakebite coagulopathy, Investigating the function of circulating microparticles, Investigating a novel target on the surface of leukaemia cells, Epigenetics of atherothrombotic disease.

Qualifications

  • PhD (Medicine), University of Newcastle
  • Bachelor of Science (Honours), University of Newcastle
  • Graduate Diploma in Clinical Epidemiology, University of Newcastle

Keywords

  • Cardiovascular Medicine
  • Haematology

Fields of Research

Code Description Percentage
060499 Genetics not elsewhere classified 30
110399 Clinical Sciences not elsewhere classified 40
110299 Cardiorespiratory Medicine and Haematology not elsewhere classified 30
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Journal article (58 outputs)

Year Citation Altmetrics Link
2015 Isbister GK, Maduwage K, Scorgie FE, Shahmy S, Mohamed F, Abeysinghe C, et al., 'Venom Concentrations and Clotting Factor Levels in a Prospective Cohort of Russell's Viper Bites with Coagulopathy.', PLoS Negl Trop Dis, 9 e0003968 (2015)
DOI 10.1371/journal.pntd.0003968
Co-authors Geoff Isbister
2015 Holliday EG, Traylor M, Malik R, Bevan S, Falcone G, Hopewell JC, et al., 'Genetic overlap between diagnostic subtypes of ischemic stroke.', Stroke, 46 615-619 (2015)
DOI 10.1161/STROKEAHA.114.007930
Co-authors Chris Levi, Liz Holliday, Christopher Oldmeadow, Rodney Scott, Jane Maguire, John Attia
2015 Ahmed AF, de Bock CE, Lincz LF, Pundavela J, Zouikr I, Sontag E, et al., 'FAT1 cadherin acts upstream of Hippo signalling through TAZ to regulate neuronal differentiation.', Cellular and molecular life sciences : CMLS, (2015)
DOI 10.1007/s00018-015-1955-6
Co-authors Rick Thorne, Hubert Hondermarck
2014 Clancy P, Lincz LF, Maguire J, McEvoy M, Koblar SA, Golledge J, 'Tenascin-C is increased in atherothrombotic stroke patients and has an anti-inflammatory effect in the human carotid artery.', Biofactors, 40 448-457 (2014) [C1]
DOI 10.1002/biof.1170
Co-authors Jane Maguire
2014 Maduwage K, O'Leary MA, Scorgie FE, Shahmy S, Mohamed F, Abeysinghe C, et al., 'Detection of venom after antivenom is not associated with persistent coagulopathy in a prospective cohort of Russell's viper (Daboia russelii) envenomings.', PLoS Negl Trop Dis, 8 e3304 (2014) [C1]
DOI 10.1371/journal.pntd.0003304
Citations Scopus - 1
Co-authors Geoff Isbister
2014 Lincz LF, Scorgie FE, Johnston CI, O'Leary M, Prasad R, Seldon M, et al., 'Comparative sensitivity of commercially available aPTT reagents to mulga snake (Pseudechis australis) venom.', Pathology, 46 444-449 (2014) [C1]
DOI 10.1097/PAT.0000000000000120
Citations Scopus - 1Web of Science - 1
Co-authors Geoff Isbister
2014 Pundavela J, Demont Y, Jobling P, Lincz LF, Roselli S, Thorne RF, et al., 'ProNGF correlates with Gleason score and is a potential driver of nerve infiltration in prostate cancer', American Journal of Pathology, 184 3156-3162 (2014) [C1]

Nerve infiltration is essential to prostate cancer progression, but the mechanism by which nerves are attracted to prostate tumors remains unknown. We report that the precursor of... [more]

Nerve infiltration is essential to prostate cancer progression, but the mechanism by which nerves are attracted to prostate tumors remains unknown. We report that the precursor of nerve growth factor (proNGF) is overexpressed in prostate cancer and involved in the ability of prostate cancer cells to induce axonogenesis. A series of 120 prostate cancer and benign prostate hyperplasia (BPH) samples were analyzed by IHC for proNGF. ProNGF was mainly localized in the cytoplasm of epithelial cells, with marked expression in cancer compared with BPH. Importantly, the proNGF level positively correlated with the Gleason score (n = 104, tB = 0.51). A higher level of proNGF was observed in tumors with a Gleason score of =8 compared with a Gleason score of 7 and 6 (P < 0.001). In vitro, proNGF was detected in LNCaP, DU145, and PC-3 prostate cancer cells and BPH-1 cells but not in RWPE-1 immortalized nontumorigenic prostate epithelial cells or primary normal prostate epithelial cells. Co-culture of PC12 neuronal-like cells or 50B11 neurons with PC-3 cells resulted in neurite outgrowth in neuronal cells that was inhibited by blocking antibodies against proNGF, indicating that prostate cancer cells can induce axonogenesis via secretion of proNGF. These data reveal that ProNGF is a biomarker associated with high-risk prostate cancers and a potential driver of infiltration by nerves.

DOI 10.1016/j.ajpath.2014.08.009
Citations Scopus - 2Web of Science - 2
Co-authors Hubert Hondermarck, Rick Thorne, Marjorie Walker, Phillip Jobling
2014 Golledge J, Clancy P, Maguire J, Lincz L, Koblar S, Mcevoy M, et al., 'Plasma angiopoietin-1 is lower after ischemic stroke and associated with major disability but not stroke incidence', Stroke, 45 1064-1068 (2014) [C1]
DOI 10.1161/STROKEAHA.113.004339
Citations Scopus - 1
Co-authors Jane Maguire, Chris Levi, John Attia
2014 Golledge J, Clancy P, Maguire J, Lincz L, Koblar S, Mcevoy M, et al., 'Plasma angiopoietin-1 is lower after ischemic stroke and associated with major disability but not stroke incidence', Stroke, 45 1064-1068 (2014) [C1]

BACKGROUND AND PURPOSE - : Studies in rodent models suggest that upregulating angiopoietin-1 (Angpt1) improves stroke outcomes. The aims of this study were to assess the associati... [more]

BACKGROUND AND PURPOSE - : Studies in rodent models suggest that upregulating angiopoietin-1 (Angpt1) improves stroke outcomes. The aims of this study were to assess the association of plasma Angpt1 with stroke occurrence and outcome. METHODS - : Plasma Angpt1 was measured in 336 patients who had experienced a recent stroke and 321 healthy controls with no stroke history. Patients with stroke (n=285) were reassessed at 3 months and plasma Angpt1 concentration on admission compared between those with severe and minor disability as assessed by the modified Rankin scale. In a separate cohort of 4032 community-acquired older men prospectively followed for a minimum of 6 years, the association of plasma Angpt1 with stroke incidence was examined. RESULTS - : Median plasma Angpt1 was 3-fold lower in patients who had experienced a recent stroke (6.42, interquartile range, 4.26-9.53 compared with 17.36; interquartile range, 14.01-22.46 ng/mL; P<0.001) and remained associated with stroke after adjustment for other risk factors. Plasma Angpt1 concentrations on admission were lower in patients who had severe disability or died at 3 months (median, 5.52; interquartile range, 3.81-8.75 ng/mL for modified Rankin scale 3-6; n=91) compared with those with minor disability (median, 7.04; interquartile range, 4.75-9.92 ng/mL for modified Rankin scale 0-2; n=194), P=0.012, and remained negatively associated with severe disability or death after adjusting for other risk factors. Plasma Angpt1 was not predictive of stroke incidence in community-dwelling older men. CONCLUSIONS - : Plasma Angpt1 concentrations are low after ischemic stroke particularly in patients with poor stroke outcomes at 3 months. Interventions effective at upregulating Angpt1 could potentially improve stroke outcomes. © 2014 American Heart Association, Inc.

DOI 10.1161/STROKEAHA.113.004339
Citations Scopus - 1Web of Science - 1
Co-authors Chris Levi, John Attia, Jane Maguire
2014 Phang M, Scorgie FE, Seldon M, Garg ML, Lincz LF, 'Reduction of prothrombin and Factor V levels following supplementation with omega-3 fatty acids is sex dependent: A randomised controlled study', Journal of Nutritional Biochemistry, 25 997-1002 (2014) [C1]

Background: LCn-3PUFA comprised of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) offer cardioprotection involving a decrease in coagulant activity; however, the evide... [more]

Background: LCn-3PUFA comprised of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) offer cardioprotection involving a decrease in coagulant activity; however, the evidence is equivocal. We have previously demonstrated that the acute (24. h) effects and chronic (4. weeks) effects of LCn-3PUFA supplementation on platelet aggregation in human subjects are sex specific. This study investigated the mechanisms of the sex-dependent effects of LCn-3PUFA with 4. weeks supplementation of EPA-rich vs. DHA-rich oils on procoagulant and platelet activity in healthy subjects. Design: A double-blinded, placebo-controlled randomised trial was conducted in 94 healthy adults: male (. n=41) and female (. n=53). Platelet coagulation parameters including factors I, II, V, VII, VIII, IX, X, vWF:Ag and endogenous thrombin potential were measured at baseline and 4. weeks postsupplementation with EPA-rich or DHA-rich oil capsules. Results: We have previously reported that platelet aggregation is specifically reduced by supplementation with EPA in males and DHA in females. This sex-specific effect was also observed for decreases in plasma levels of Factor II (-7.9±3.8%, P=.026), Factor V (-6.5±4.5%, P=.022) and vWF:Ag (-7.3±2.1%, P=.034) and was most pronounced in males supplemented with EPA. In contrast, DHA-mediated reduction in platelet aggregation in females was not accompanied by any significant changes in the coagulation parameters tested. Conclusion: Significant interactions between sex and specific LCn-3PUFA exist to reduce procoagulant activity differentially in males vs. females and could have profound effects on managing risk of thrombotic disease.

DOI 10.1016/j.jnutbio.2014.05.001
Co-authors Manohar Garg
2014 Clancy P, Lincz LF, Maguire J, McEvoy M, Koblar SA, Golledge J, 'Tenascin-C is increased in atherothrombotic stroke patients and has an anti-inflammatory effect in the human carotid artery.', BioFactors (Oxford, England), 40 448-457 (2014) [C1]
DOI 10.1002/biof.1170
Citations Scopus - 1Web of Science - 1
Co-authors Jane Maguire
2013 Phang M, Lincz LF, Garg ML, 'Eicosapentaenoic and Docosahexaenoic Acid Supplementations Reduce Platelet Aggregation and Hemostatic Markers Differentially in Men and Women', JOURNAL OF NUTRITION, 143 457-463 (2013) [C1]
DOI 10.3945/jn.112.171249
Citations Scopus - 13Web of Science - 14
Co-authors Manohar Garg
2013 Ardjmand A, de Bock CE, Shahrokhi S, Lincz LF, Boyd AW, Burns GF, Thorne RF, 'Fat1 cadherin provides a novel minimal residual disease marker in acute lymphoblastic leukemia', HEMATOLOGY, 18 315-321 (2013) [C1]
DOI 10.1179/1607845413Y.0000000080
Co-authors Rick Thorne
2013 Isbister GK, Buckley NA, Page CB, Scorgie FE, Lincz LF, Seldon M, Brown SGA, 'A randomized controlled trial of fresh frozen plasma for treating venom-induced consumption coagulopathy in cases of Australian snakebite (ASP-18)', Journal of Thrombosis and Haemostasis, 11 1310-1318 (2013) [C1]
DOI 10.1111/jth.12218
Citations Scopus - 9Web of Science - 9
Co-authors Geoff Isbister
2013 Maduwage K, Scorgie FE, Silva A, Shahmy S, Mohamed F, Abeysinghe C, et al., 'Hump-nosed pit viper (Hypnale hypnale) envenoming causes mild coagulopathy with incomplete clotting factor consumption', CLINICAL TOXICOLOGY, 51 527-531 (2013) [C1]
DOI 10.3109/15563650.2013.811589
Citations Scopus - 6Web of Science - 5
Co-authors Geoff Isbister
2013 Alkhatatbeh MJ, Enjeti AK, Acharya S, Thorne RF, Lincz LF, 'The origin of circulating CD36 in type 2 diabetes', NUTRITION & DIABETES, 3 (2013) [C1]
DOI 10.1038/nutd.2013.1
Citations Scopus - 9Web of Science - 6
Co-authors Rick Thorne
2012 Cheng YC, Anderson CD, Bione S, Keene K, Maguire JM, Nalls M, et al., 'Are myocardial infarction-associated single-nucleotide polymorphisms associated with ischemic stroke?', Stroke, 43 980-U143 (2012) [C1]
Citations Scopus - 11Web of Science - 11
Co-authors Jane Maguire, Pablo Moscato, John Attia, Rodney Scott, Liz Holliday, Chris Levi
2012 Lincz L, Scorgie FE, Enjeti A, Seldon M, 'Variable plasma levels of Factor V Leiden correlate with circulating platelet microparticles in carriers of Factor V Leiden', Thrombosis Research, 129 192-196 (2012) [C1]
Citations Scopus - 2Web of Science - 2
2012 De Bock CE, Ardjmand Ghahestani A, Molloy TJ, Bone SM, Johnstone DM, Campbell DM, et al., 'The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis-relapse samples of precursor B-cell acute lymphoblastic leukemia', Leukemia, 26 918-926 (2012) [C1]
Citations Scopus - 11Web of Science - 12
Co-authors Rick Thorne
2012 Phang M, Sinclair AJ, Lincz L, Garg ML, 'Gender-specific inhibition of platelet aggregation following omega-3 fatty acid supplementation', Nutrition Metabolism and Cardiovascular Diseases, 22 109-114 (2012) [C1]
Citations Scopus - 17Web of Science - 12
Co-authors Manohar Garg
2012 Phang M, Lincz L, Seldon M, Garg ML, 'Acute supplementation with eicosapentaenoic acid reduces platelet microparticle activity in healthy subjects', Journal of Nutritional Biochemistry, 23 1128-1133 (2012) [C1]
Citations Scopus - 6Web of Science - 6
Co-authors Manohar Garg
2012 Holliday EG, Maguire JM, Evans T-J, Koblar SA, Jannes J, Sturm J, et al., 'Common variants at 6p21.1 are associated with large artery atherosclerotic stroke', Nature Genetics, 44 1147-1153 (2012) [C1]
Citations Scopus - 47Web of Science - 47
Co-authors Chris Levi, Liz Holliday, Christopher Oldmeadow, Rodney Scott, Roseanne Peel, Mark Parsons, John Attia, Pablo Moscato, Jane Maguire, Wayne Smith
2012 Garg MB, Lincz L, Adler K, Scorgie FE, Ackland S, Sakoff JA, 'Predicting 5-Fluorouracil toxicity in colorectal cancer patients from peripheral blood cell telomere length - A multivariate analysis', British Journal of Cancer, 107 1525-1533 (2012) [C1]
Citations Scopus - 5Web of Science - 6
Co-authors Jennette Sakoff, Stephen Ackland
2011 Alkhatatbeh MJ, Mhaidat NM, Enjeti AK, Lincz L, Thorne RF, 'The putative diabetic plasma marker, soluble CD36, is non-cleaved, non-soluble and entirely associated with microparticles', Journal of Thrombosis and Haemostasis, 9 844-851 (2011) [C1]
DOI 10.1111/j.1538-7836.2011.04220.x
Citations Scopus - 17Web of Science - 17
Co-authors Rick Thorne
2011 Golledge J, Clancy P, Maguire JM, Lincz L, Koblar S, 'The role of tenascin C in cardiovascular disease', Cardiovascular Research, 92 19-28 (2011) [C1]
DOI 10.1093/cvr/cvr183
Citations Scopus - 18Web of Science - 20
Co-authors Jane Maguire
2011 Maguire JM, Thakkinstian A, Levi CR, Lincz L, Bisset L, Sturm J, et al., 'Impact of COX-2 rs5275 and rs20417 and GPIIIa rs5918 polymorphisms on 90-day ischemic stroke functional outcome: A novel finding', Journal of Stroke and Cerebrovascular Diseases, 20 134-144 (2011) [C1]
DOI 10.1016/j.jstrokecerebrovasdis.2009.10.011
Citations Scopus - 22Web of Science - 21
Co-authors Chris Levi, Jane Maguire, John Attia, Rodney Scott
2011 McGettigan P, Lincz L, Attia JR, McElduff P, Bissett L, Peel R, et al., 'The risk of coronary thrombosis with cyclo-oxygenase-2 inhibitors does not vary with polymorphisms in two regions of the cyclo-oxygenase-2 gene', British Journal of Clinical Pharmacology, 72 707-714 (2011) [C1]
DOI 10.1111/j.1365-2125.2011.03957.x
Citations Scopus - 6Web of Science - 6
Co-authors Barrie Stokes, Mddah01, Patrick Mcelduff, John Attia, Roseanne Peel
2010 Isbister GK, Woods D, Alley S, O'Leary MA, Seldon M, Lincz L, 'Endogenous thrombin potential as a novel method for the characterization of procoagulant snake venoms and the efficacy of antivenom', Toxicon, 56 75-85 (2010) [C1]
DOI 10.1016/j.toxicon.2010.03.013
Citations Scopus - 17Web of Science - 16
Co-authors Geoff Isbister
2010 Enjeti A, Lincz L, Scorgie FE, Seldon MR, 'Circulating microparticles are elevated in carriers of Factor V Leiden', Thrombosis Research, 126 250-253 (2010) [C1]
DOI 10.1016/j.thromres.2009.11.019
Citations Scopus - 6Web of Science - 6
2010 De Bock CE, Garg ML, Scott NM, Sakoff JA, Scorgie FE, Ackland S, Lincz L, 'Association of thymidylate synthase enhancer region polymorphisms with thymidylate synthase activity in vivo', Pharmacogenomics Journal, 1-8 (2010) [C1]
DOI 10.1038/tpj.2010.43
Citations Scopus - 7Web of Science - 7
Co-authors Stephen Ackland, Jennette Sakoff, Manohar Garg
2009 Isbister GK, Scorgie FE, Seldon MR, Lincz L, 'Clinical relevance of brown snake (Pseudonaja spp) factor V escaping hemostatic regulation', Blood, 114 2563 (2009) [C3]
DOI 10.1182/blood-2009-06-227306
Citations Scopus - 1
Co-authors Geoff Isbister
2009 Lincz L, Gupta SA, Wratten C, Kilmurray J, Nash S, Seldon M, et al., 'Thrombin generation as a predictor of radiotherapy induced skin erythema', Radiotherapy and Oncology, 90 136-140 (2009) [C1]
DOI 10.1016/j.radonc.2008.10.002
Citations Scopus - 2Web of Science - 1
2008 Lincz L, Mudge L-M, Scorgie FE, Sakoff JA, Hamilton C, Seldon MR, 'Quantification of hTERT splice variants in melanoma by SYBR green real-time polymerase chain reaction indicates a negative regulatory role for the [beta symbol] deletion variant', Neoplasia, 10 1131-1137 (2008) [C1]
DOI 10.1593/neo.08644
Citations Scopus - 21Web of Science - 20
Co-authors Jennette Sakoff
2008 Enjeti AK, Lincz L, Seldon MR, 'Bio-maleimide as a generic stain for detection and quantitation of microparticles', International Journal of Laboratory Hematology, 30 196-199 (2008) [C1]
DOI 10.1111/j.1751-553x.2007.00937.x
Citations Scopus - 13Web of Science - 12
2008 Maguire JM, Thakkinstian A, Sturm J, Levi CR, Lincz L, Parsons MW, et al., 'Polymorphisms in platelet glycoprotein 1b [alpha] and factor VII and risk of ischemic stroke', Stroke, 39 1710-1716 (2008) [C1]
DOI 10.1161/strokeaha.107.507228
Citations Scopus - 24Web of Science - 23
Co-authors Chris Levi, Mark Parsons, John Attia, Jane Maguire
2008 Enjeti AK, Lincz L, Seldon MR, 'Microparticles in health and disease', Seminars in Thrombosis and Haemostasis, 34 683-692 (2008) [C1]
DOI 10.1055/s-0028-1104547
Citations Scopus - 40Web of Science - 41
2007 Lincz L, Adams MJ, Scorgie FE, Thom J, Baker RI, Seldon M, 'Polymorphisms of the tissue factor pathway inhibitor gene are associated with venous thromboembolism in the antiphospholipid syndrome and carriers of factor V Leiden', Blood Coagulation & Fibrinolysis, 18 559-564 (2007) [C1]
DOI 10.1097/MBC.0b013e3281eec977
Citations Scopus - 10Web of Science - 11
2007 Attia JR, Thakkinstian A, Wang Y, Lincz L, Parsons MW, Sturm J, et al., 'The PAI-1 4G/5G gene polymorphism and ischemic stroke: An association study and meta-analysis', Journal of Stroke and Cerebrovascular Diseases, 16 173-179 (2007) [C1]
DOI 10.1016/j.jstrokecerebrovasdis.2007.03.002
Citations Scopus - 31
Co-authors Rodney Scott, Chris Levi, John Attia, Mark Parsons
2007 Au GG, Lincz L, Enno A, Shafren DR, 'Oncolytic Coxsackievirus A21 as a novel therapy for multiple myeloma', British Journal of Haematology, 137 133-141 (2007) [C1]
DOI 10.1111/j.1365-2141.2007.06550.x
Citations Scopus - 21Web of Science - 18
Co-authors Gough Au
2007 Lincz L, Scorgie FE, Garg MB, Ackland S, 'Identification of a novel single nucleotide polymorphism in the second tandem repeat sequence of the thymidylate synthase 2R allele', International Journal of Cancer, 120 1930-1934 (2007) [C1]
DOI 10.1002/ijc.22568
Citations Scopus - 29Web of Science - 26
Co-authors Stephen Ackland
2007 Lincz L, Scorgie FE, Garg ML, Ackland S, 'Reply to the letter to the editor 'Classification of thymidylate synthase gene enhancer region polymorphisms'', International Journal of Cancer, 121 2581-2582 (2007) [C3]
DOI 10.1002/ijc.22987
Co-authors Stephen Ackland, Manohar Garg
2007 Enjeti AK, Lincz L, Seldon M, 'Detection and measurement of microparticles: An evolving research tool for vascular biology', Seminars in Thrombosis and Hemostasis, 33 771-779 (2007) [C1]
DOI 10.1055/s-2007-1000369
Citations Scopus - 71Web of Science - 69
2007 Lincz L, Scorgie FE, Robertson R, Enno A, 'Genetic variations in benzene metabolism and susceptibility to multiple myeloma', Leukemia Research, 31 759-763 (2007) [C1]
DOI 10.1016/j.leukres.2006.07.012
Citations Scopus - 12Web of Science - 10
2006 Lincz L, Lonergan A, Scorgie FE, Rowlings PA, Gibson R, Lawrie A, Seldon MR, 'Endogenous thrombin potential for predicting risk of venous thromboembolism in carriers of Factor V Leiden', Pathophysiology of Haemostatis and Thrombosis, 35 435-439 (2006) [C1]
DOI 10.1159/000102050
Citations Scopus - 12Web of Science - 13
2004 Lincz L, Scorgie F, Sakoff J, Fagan K, Ackland S, Enno A, 'Telomere length predicts neutrophil recovery in absence of G-CSF after autologous peripheral blood stem cell transplantation', Bone Marrow Transplant, 34 439-445 (2004) [C1]
DOI 10.1038/sj.bmt.1704607
Citations Scopus - 3Web of Science - 3
Co-authors Stephen Ackland, Jennette Sakoff
2004 Lincz L, Kerridge I, Scorgie FE, Bailey M, Enno A, Spencer A, 'Xenobiotic gene polymorphisms and susceptibility to multiple myeloma', Haematologica, 89 628-629 (2004) [C3]
Citations Scopus - 33Web of Science - 27
2003 Lincz L, Scorgie FE, Kerridge I, Potts R, Spencer A, Enno A, 'Methionine synthase genetic polymorphism MS A2756G alters susceptibility to follicular but not diffuse large B-cell non-Hodgkin's lymphoma or multiple myeloma', British Journal of Haematology, 120 1051-1054 (2003) [C1]
DOI 10.1046/j.1365-2141.2003.04220.x
Citations Scopus - 51Web of Science - 49
2002 Sakoff J, De Waal E, Garg M, Denham J, Scorgie F, Enno A, et al., 'Telomere Length in Haemopoietic Stem Cells can be Determined from that of Mononuclear Blood Cells or Whole Blood', Leukemia and Lymphoma, 43(10) 2017-2020 (2002) [C1]
Citations Scopus - 22Web of Science - 23
Co-authors Stephen Ackland, Jennette Sakoff
2002 Kerridge I, Lincz L, Scorgie F, Hickey D, Granter N, Spencer A, 'Association between xenobiotic gene polymorphisms and non-Hodgkin's lymphoma risk', BRITISH JOURNAL OF HAEMATOLOGY, 118 477-481 (2002)
DOI 10.1046/j.1365-2141.2002.03606.x
Citations Scopus - 72Web of Science - 61
2002 Kerridge I, Lincz LF, Scorgie FE, Granter N, Hickey D, Enno A, Spencer A, 'Xenobiotic enzyme polymorphisms and lymphoma susceptibility', Br. J. Haemtol, 118 477-481 (2002) [C1]
2001 Lincz L, Yeh T-X, Spencer A, 'TRAIL-induced eradication of primary tumour cells from multiple myeloma patient bone marrows is not related to TRAIL receptor expression or prior chemotherapy', Leukemia, 15 1650-1657 (2001) [C1]
Citations Scopus - 51Web of Science - 57
2001 Lincz L, Crooks RL, Way SL, Granter N, Spencer A, 'Tumour Kinetics in Multiple Myeloma Before, During, and After Treatment', Leukemia & Lymphoma, 40 373-384 (2001) [C1]
Citations Scopus - 4Web of Science - 3
2000 Lincz LF, Yeh TH, Enno A, Spencer A, 'Variations in TRAIL-induced apoptosis of freshly obtained myeloma cells are not related to TRAIL receptor expression or prior chemotherapy.', BLOOD, 96 162A-162A (2000)
2000 Lincz LF, Yeh T-H, Enno A, Spencer A, 'Variations in trail-induced apoptosis of freshly obtained myeloma cells are not related to trail receptor expression or prior chemotherapy', Blood, 96 (2000)

TNF-related apoptosis-inducing ligand (TRAIL) is a potent and selective inducer of apoptosis in malignant cells. Using the combined methods of Annexin V labelling, cell cycle anal... [more]

TNF-related apoptosis-inducing ligand (TRAIL) is a potent and selective inducer of apoptosis in malignant cells. Using the combined methods of Annexin V labelling, cell cycle analysis and DNA electrophoresis, we have demonstrated susceptibility to TRAILinduced apoptosis in the human multiple myeloma (MM) cell lines NCI H929, RPMI 8226, OPM-2 and LP-1, while the lymphoblastoid cell lines (LCL) U266 and MC/CAR were resistant. Two different forms of TRAIL were tested: purified human recombinant soluble TRAIL (s-TRAIL; residues 114-281; Biomol, Plymouth Meeting, PA) demonstrated maximal apoptosis induction at 1 u,g/ml in sensitive cell lines, while a leucine zipper construct (LZ-TRAIL; Immunex Corp., Seattle, WA) was equally effective when used at a concentration of 500 ng/ml. BM samples obtained from 16 MM patients at various stages of disease were incubated for 24 hours with or without either 2u,g/tnl sTRAIL (n = 8) or lug/ml LZ-TRAIL (n = 8). The percentage of viable MM cells was then determined by flow cytometric quantification of anti-CD138 stained cells and the relative TRAIL-induced reduction in MM cells calculated using the formula: [(Untreated)-(TRAlLTreated)]/Untreated x 100%. BM samples from 6 of 16 (38%) patients demonstrated a significant ( 10%) relative reduction in the number of MM cells following TRAIL incubation (range: 11% to 59%). This did not correlate with prior therapy, as a reduction was seen in 2/5 samples obtained from patients at diagnosis, 2/5 samples following standard-dose chemotherapy and 2/6 samples following high-dose chemotherapy. The relationship between TRAIL-receptor expression (TRAIL-R1, R2, R3, R4 and OPG) and TRAILinduced apoptosis was examined in 2 sensitive (NCI H929, RPMI 8226) and the 2 resistant cell lines and 5 MM BM samples (2 sensitive, 3 resistant) utilising RT-PCR and surface immunostaining of purified MM cells. Concordance between TRAIL-receptor mRNA detection and cell surface expression was shown in all cell lines. Furthermore, all cell lines and patient samples demonstrated mRNA expression for the intracellular deathdomain containing TRAIL-R1. Variable expression of the 2 decoy (TRAIL-R3 and R4) and soluble (OPG) receptors was seen and this did not correlate with TRAIL sensitivity. We conclude that MM cell expression of death effector receptors for TRAIL is insufficient to confer sensitivity to TRAIL-induced apoptosis but that in a significant minority of patients, irrespective of prior therapy, MM cells are sensitive to TRAIL-induced apoptosis.

1998 Lincz L, 'Deciphering the apoptotic pathway: All roads lead to death', Immunology & Cell Biology, 76 1-19 (1998) [C1]
Citations Scopus - 90Web of Science - 91
1997 Lincz L, Buret A, Burns GF, 'Formation of spheroid structures in a human colon carcinoma cell line involves a complex series of intercellular rearrangements', Differentiation, 61 261-274 (1997) [C1]
Citations Scopus - 12Web of Science - 10
1996 Dorahy DJ, Lincz LF, Meldrum CJ, Burns GF, 'Biochemical isolation of a membrane microdomain from resting platelets highly enriched in the plasma membrane glycoprotein CD36', BIOCHEMICAL JOURNAL, 319 67-72 (1996)
Citations Scopus - 102Web of Science - 105
1995 BATES RC, LINCZ LF, BURNS GF, 'INVOLVEMENT OF INTEGRINS IN CELL-SURVIVAL', CANCER AND METASTASIS REVIEWS, 14 191-203 (1995)
DOI 10.1007/BF00690291
Citations Scopus - 79Web of Science - 81
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Conference (37 outputs)

Year Citation Altmetrics Link
2014 Prawira A, Garg MB, Sakoff JA, Lincz LF, Adler K, Scorgie FE, Ackland SP, 'FACTORS PREDICTING RESPONSE AND SURVIVAL IN COLORECTAL CANCER PATIENTS RECEIVING ADJUVANT 5-FLUOROURACIL CHEMOTHERAPY: 10-YEAR FOLLOW-UP OF A PROSPECTIVE PATIENT COHORT', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2014) [E3]
Co-authors Stephen Ackland, Jennette Sakoff
2013 Enjeti A, D'Cruz A, Seldon M, Lincz L, 'Circulating microparticle number and function vary with age: a study of 120 healthy blood donors', JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2013) [E3]
2012 Phang M, Lincz L, Garg ML, 'Efficacy of EPA- and DHA- rich oils on platelet function in healthy men and women', Abstracts. International Conference and Exhibition on Nutraceuticals and Functional Foods, Hawaii, USA (2012) [E3]
Co-authors Manohar Garg
2012 Phang M, Lincz L, Garg ML, 'Eicosapentaenoic acid versus docosahexaenoic acid rich fish oils: Effect on platelet physiological response', Conference Handbook. Food Structures, Digestion and Health Conference, Palmerston North, NZ (2012) [E3]
Co-authors Manohar Garg
2012 Lincz L, Johnston CI, Scorgie FE, O'Leary MA, Prasad R, Seldon MR, et al., 'Comparative sensitivity of different commercially available aPTT reagents to a clinically relevant 'coagulation inhibitor'', HAA 2012: 2012 Co-Joint Scientific Meeting. ASTH Posters, Melbourne (2012) [E3]
Co-authors Geoff Isbister
2012 Scorgie FE, Maduwage KP, Lincz L, Shahmy S, Mohamed F, Seldon MR, Isbister GK, 'Comparison of the haemostatic effects of three different procoagulant snake venoms in human envenoming', HAA 2012: 2012 Co-Joint Scientific Meeting. ASTH Posters, Melbourne (2012) [E3]
Co-authors Geoff Isbister
2012 Lincz L, 'The nature and origin of circulating CD36 in type 2 diabetes: A role for microparticles', HAA 2012: 2012 Co-Joint Scientific Meeting. Abstracts, Melbourne (2012) [E3]
2012 Phang M, Lincz L, Garg ML, 'Omega-3 polyunsaturated fatty acids and platelet function: Sex dependence', Indian Journal of Hypertension, Mumbai, India (2012) [E3]
Co-authors Manohar Garg
2012 Phang M, Lincz L, Seldon MR, Garg ML, 'Differential effects of eicosapentaenoic and docosahexaenoic acids on platelet aggregation and hemostatic markers', Proceedings of the Nutrition Society of Australia, Wollongong, NSW (2012) [E3]
Co-authors Manohar Garg
2012 Sakoff JA, Garg MB, Lincz L, Adler K, Scorgie FE, Ackland S, 'Predicting chemotherapy-induced toxicity in cancer patients from peripheral blood telomere length', European Journal of Cancer, Barcelona, Spain (2012) [E3]
Co-authors Jennette Sakoff, Stephen Ackland
2011 Maguire JM, Holliday EG, Sturm J, Golledge J, Lewis M, Koblar S, et al., 'Australian stroke genetics collaborative: Genetic associations with ischaemic stroke functional outcome', International Journal of Stroke, Adelaide, SA (2011) [E3]
Co-authors Jane Maguire, John Attia, Mark Parsons, Pablo Moscato, Liz Holliday, Chris Levi, Rodney Scott
2011 Phang M, Lincz L, Garg ML, 'Gender specific effects of long-term dietary EPA and DHA supplementation in platelet aggregation in healthy human subjects', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
Co-authors Manohar Garg
2011 Alkhatatbeh MJ, Mhaidat NM, Enjeti AK, Lincz LF, Thorne RF, 'Circulating plasma CD36+microparticles as a marker of type 2 diabetes and its complications', Clinical Biochemistry, Mashhad, Iran (2011) [E3]
Co-authors Rick Thorne
2011 Ardjmand Ghahestani A, De Bock CE, Molloy TJ, Bone SM, Johnstone DM, Campbell DM, et al., 'Altered expression of Fat1 cadherin, a novel tumor marker for acute lymphoblastic leukemia', Clinical Biochemistry, Mashhad, Iran (2011) [E3]
Co-authors Rick Thorne
2010 Phang M, Lincz L, Garg ML, 'Gender specific role of n-3PUFA to inhibit microparticle activity in healthy humans', 15th World Congress on Clinical Nutrition, El Sokhna, Egypt (2010) [E3]
Co-authors Manohar Garg
2010 Sakoff JA, Garg M, Adler K, Scorgie FE, Lincz L, Ackland S, 'Telomere length in peripheral blood mononuclear cells (PBMNC) predicts for leukopenia, neutropenia and mucositis in colorectal cancer patients treated with 5FU', AACR 101st Annual Meeting 2010. Abstracts, Washington, DC (2010) [E3]
Co-authors Stephen Ackland, Jennette Sakoff
2010 Phang M, Sinclair AJ, Lincz L, Garg ML, 'Omega-3 polyunsaturated fatty acis inhibit platelet-derived microparticle activiity in healthy human subjects', APSAVD 2010 Congress. AAS 2010 Annual Scientific Meeting. Abstract Book, Cairns, QLD (2010) [E3]
Co-authors Manohar Garg
2010 Lincz L, Scorgie F, Phang M, Garg ML, Enjeti A, Seldo M, 'Variability in platelet microparticle profile and aggregation in healthy males and females', Annual Scientific Meeting of the Haematology Society of Australia and New Zealand. Handbook and Program, Auckland, New Zealand (2010) [E3]
Co-authors Manohar Garg
2010 Phang M, Lincz L, Sinclair AJ, Garg ML, 'Platelet-derived microparticle activity is inhibited by omega-3 fatty acid supplementation', Proceedings of the Nutrition Society of Australia, Perth (2010) [E3]
Co-authors Manohar Garg
2010 Sakoff JA, Garg M, Adler K, Scorgie FE, Lincz L, Ackland S, 'Short telomeres in PBMNC predicts for haematological toxicity in colorectal cancer patients treated with 5FU', Sydney Cancer Conference 2010. Profiling Risk, Personalising Treatment and Predicting Outcomes. Conference Program and Abstract Book, Sydney, NSW (2010) [E3]
Co-authors Jennette Sakoff, Stephen Ackland
2010 Maguire JM, Thakkinstian A, Levi CR, Lincz L, Bissett KE, Sturm J, et al., 'Genetic influences on ischemic stroke 90-day functional outcome: A novel association', Circulation, Beijing (2010) [E3]
Co-authors Jane Maguire, John Attia, Chris Levi, Rodney Scott
2009 Lincz L, Woods D, Alley S, O'Leary MA, Seldon MR, Isbister GK, 'Endogenous thrombin potential as a novel method for characterisation of procoagulant snake venoms', Journal of Thrombosis and Haemostasis, Boston, MA (2009) [E3]
DOI 10.1111/j.1538-7836.2009.03473_2.x
Co-authors Geoff Isbister
2009 Isbister GK, Scorgie F, Brown SGA, O'Leary MA, Seldon MR, Lincz L, 'Coagulation factor deficiencies associated with venom induced consumption coagulopathy in Australian snake envenoming', Clinical Toxicology, Stockholm, Sweden (2009) [E3]
Citations Web of Science - 4
Co-authors Geoff Isbister
2009 Henry D, Lincz L, Attia JR, McElduff P, Bisset L, Peel R, et al., 'Polymorphisms in two regions of the cyclo-oxygenase-2 gene associated with variation in risk of coronary thrombosis with cyclo-oxygenase-2 inhibitors', Basic & Clinical Pharmacology & Toxicology, Edinburgh, UK (2009) [E3]
DOI 10.1111/j.1742-7843.2009.00436.x
Co-authors Roseanne Peel, John Attia, Patrick Mcelduff
2009 Phang M, Sinclair AJ, Lincz L, Garg ML, 'Differential effects of dietary EPA or DHA supplementation on platelet aggregation in healthy male and female subjects', Atherosclerosis Society Annual Scientific Meeting 2009: Meeting Book, Melbourne, VIC (2009) [E3]
Co-authors Manohar Garg
2009 Phang M, Sinclair AJ, Lincz L, Garg ML, 'Differential effects of a single oral dose of EPA or DHA rich fish oil on platelet aggregation in health human subjects', Proceedings of the Nutrition Society of Australia, Newcastle, NSW (2009) [E3]
Co-authors Manohar Garg
2009 Maguire J, Thakkinstian A, Attia JR, Lincz L, Bisset L, Sturm J, et al., 'Impact of COX-2 RS5275, RS20417 and GPIIIA RS5918 polymorphisms on 90 day ischaemic stroke functional outcome: A novel association', Cerebrovascular Diseases, Stockholm, Sweden (2009) [E3]
DOI 10.1159/000221772
Co-authors Chris Levi, John Attia, Rodney Scott
2009 Henry D, Lincz L, Attia J, McElduff P, Bisset L, Peel R, et al., 'Polymorphisms in Two Regions of the Cyclo-Oxygenase-2 Gene Associated with Variation in Risk of Coronary Thrombosis with Cyclo-Oxygenase-2 Inhibitors', PHARMACOEPIDEMIOLOGY AND DRUG SAFETY (2009) [E3]
Co-authors John Attia, Roseanne Peel, Patrick Mcelduff
2008 Enjeti A, Lincz L, Scorgie F, Seldon M, 'Miniature microparticles measuring less than 0.1 um exist in human plasma and contribute to procoagulant activity', International Journal of Laboratory Hematology, Sydney, NSW (2008) [E3]
2008 Zaunders G, Thambar ST, Zhang H, Lincz L, Rowlings PA, 'Laboratory aspects of autologous marrow stem cells used to treat chronic myocardial ischaemia by direct intramyocardial injection', International Journal of Laboratory Hematology, Sydney, NSW (2008) [E3]
2008 Enjeti A, Scorgie FE, Lincz L, Brown S, Isbister GK, Seldon MR, 'Circulating microparticles in snake bite patients with microangiopathy', 50th ASH Annual Meeting and Exposition. Online Program and Abstracts, San Francisco, CA (2008) [E3]
Co-authors Geoff Isbister
2008 Lincz L, Gupta SA, Wratten CR, Kilmurray J, Nash S, Seldon M, et al., 'Thrombin generation as a predictor of radiotherapy induced skin erythema', HAA 2008 HSANZ ANZSBT ASTH: 2008 Annual Scientific Meeting: Abstracts, Perth, WA (2008) [E3]
2008 Lincz L, Woods D, Alley S, O'Leary MA, Seldon MR, Isbister GK, 'Endogenous thrombin potential (ETP) as a novel method for characterization of procoagulant snake venoms', HAA 2008 HSANZ ANZSBT ASTH: 2008 Annual Scientific Meeting: Abstracts, Perth, WA (2008) [E3]
Co-authors Geoff Isbister
2007 Maguire J, Sturm J, Attia JR, Whyte S, Bisset L, Lincz L, et al., 'A case-control genetic association study to examine platelet glycoprotein polymorphisms and ischaemic stroke risk', Internal Medicine Journal, Perth, Australia (2007) [E3]
Co-authors Mark Parsons, John Attia, Chris Levi
2003 McRae SJ, Lincz L, Scorgie F, Gibson R, Seldon M, 'The factor V Asp2194Gly polymorphism linked to the HR2 haplotype is associated with decreased factor V levels.', BLOOD 102 Meeting Abstract (2003) [E3]
2003 Lincz LF, Kerridge I, Scorgie F, Bailey M, Enno A, Spencer A, 'Xenobiotic gene polymorphisms alter susceptibility to multiple myeloma.', BLOOD, San Diego, CA (2003)
2002 Lincz LF, Enno A, 'Thalidomide induced alterations in multiple myeloma cell surface receptor expression do not affect adhesion to bone marrow stroma or correlate with VEGF secretion in vitro.', BLOOD, PHILADELPHIA, PA (2002)
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Grants and Funding

Summary

Number of grants 22
Total funding $3,202,701

Click on a grant title below to expand the full details for that specific grant.


20151 grants / $1,031,671

Helping stroke physicians choose who to thrombolyse - the "Targeting Optimal Thrombolysis Outcomes" (TOTO) study$1,031,671

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Liz Holliday, Associate Professor Jane Maguire, Associate Professor Vincent Thijs, Dr Simon Koblar, Conjoint Associate Professor Jonathan Sturm, Professor John Attia, Doctor Lisa Lincz, Doctor Andrew Bivard
Scheme Project Grant
Role Investigator
Funding Start 2015
Funding Finish 2015
GNo G1400237
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

20141 grants / $50,000

What is different about red blood cells in people with type 2 diabetes?$50,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Lisa Lincz, Doctor Rick Thorne
Scheme Project Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1401416
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20132 grants / $20,000

The genetic determinants of brain haemorrhage associated with stroke thrombolysis$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Conjoint Professor Chris Levi, Professor John Attia, Doctor Liz Holliday, Dr Simon Koblar, Professor Rodney Scott, Conjoint Associate Professor Jonathan Sturm, Associate Professor Jonathan Rosand, Doctor Lisa Lincz, Associate Professor Jane Maguire
Scheme Near Miss Grant
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1300475
Type Of Funding Internal
Category INTE
UON Y

The genetic determinants of brain haemorrhage associated with stroke thrombolysis$10,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Conjoint Professor Chris Levi, Professor John Attia, Doctor Liz Holliday, Dr Simon Koblar, Professor Rodney Scott, Conjoint Associate Professor Jonathan Sturm, Associate Professor Jonathan Rosand, Doctor Lisa Lincz, Associate Professor Jane Maguire
Scheme Near Miss
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1300704
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20122 grants / $163,394

High-Resolution Isoelectric Phosphoprotein Signalling System for Signalling Research, Biomarker Validation and Drug Development – Equipment Grant$143,394

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Rick Thorne, Professor Xu Dong Zhang, Professor Hubert Hondermarck, Conjoint Professor Stephen Ackland, Doctor Lisa Lincz, Doctor Jennette Sakoff, Emeritus Professor Leonie Ashman
Scheme Project Grant
Role Investigator
Funding Start 2012
Funding Finish 2012
GNo G1200555
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Establishment of Fat1 cadherin as biomarker and unique target for anti-cancer therapy in paediatric acute lymphoblastic leukaemia$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Rick Thorne, Doctor Charles De Bock, Doctor Lisa Lincz
Scheme Research Grant
Role Investigator
Funding Start 2012
Funding Finish 2012
GNo G1200222
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20112 grants / $580,611

Priority Research Centre for Cancer$555,811

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Conjoint Professor Stephen Ackland, Professor Xu Dong Zhang, Professor John Forbes, Emeritus Professor Leonie Ashman, Doctor Nikola Bowden, Professor Gordon Burns, Conjoint Professor Jim Denham, Professor Hubert Hondermarck, Doctor Lisa Lincz, Doctor Jennette Sakoff, Associate Professor Peter Stanwell, Doctor Rick Thorne, Doctor Nikki Verrills
Scheme Priority Research Centre
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1101013
Type Of Funding Internal
Category INTE
UON Y

How chronic psychological distress leads to premature aging$24,800

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Eugene Nalivaiko, Doctor Lisa Lincz
Scheme Project Grant
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1000986
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20101 grants / $98,000

Pathogenic Function of Plasma CD36 Mircroparticles in Mediating Complications of Type 2 Diabetes$98,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Rick Thorne, Doctor Lisa Lincz
Scheme Project Grant
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo G0900121
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20093 grants / $1,143,400

Australian stroke genetics collaborative - Genome-wide association study in ischaemic stroke$1,108,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Chris Levi, Conjoint Associate Professor Jonathan Sturm, Professor John Attia, Professor Rodney Scott, Doctor Lisa Lincz, Dr Simon Koblar, Professor Pablo Moscato
Scheme Project Grant
Role Investigator
Funding Start 2009
Funding Finish 2009
GNo G0188856
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Identification of leukaemic stem cells based upon their expression of a novel surface marker, Fat1$25,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Rick Thorne, Doctor Lisa Lincz
Scheme Project Grant
Role Investigator
Funding Start 2009
Funding Finish 2009
GNo G0189791
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Vascular Ischaemia Study$10,400

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Conjoint Professor Chris Levi, Professor John Attia, Professor Rodney Scott, Doctor Michael Seldon, Doctor Lisa Lincz, Conjoint Associate Professor Jonathan Sturm
Scheme Research Grant
Role Investigator
Funding Start 2009
Funding Finish 2009
GNo G0900120
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20083 grants / $40,125

Colibri high-performance LED illumination system for fluorescence live cell microscopy$23,225

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Rick Thorne, Dr Charles De Bock, Professor Xu Dong Zhang, Doctor Lisa Lincz, Professor Gordon Burns, Conjoint Professor Peter Hersey, Professor Dirk Van Helden, Conjoint Professor Keith Jones, Professor Roger Smith
Scheme Equipment Grant
Role Investigator
Funding Start 2008
Funding Finish 2008
GNo G0188545
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Biogenesis of circulating plasma microparticles in the metabolic syndrome$8,450

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Rick Thorne, Doctor Lisa Lincz
Scheme Pilot Grant
Role Investigator
Funding Start 2008
Funding Finish 2008
GNo G0189072
Type Of Funding Internal
Category INTE
UON Y

Biogenesis of circulating plasma microparticles in the metabolic syndrome$8,450

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Doctor Rick Thorne, Doctor Lisa Lincz
Scheme Pilot Grant
Role Investigator
Funding Start 2008
Funding Finish 2008
GNo G0189385
Type Of Funding Internal
Category INTE
UON Y

20071 grants / $20,000

A novel adhesive target involved in the survival of leukaemia cells$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Rick Thorne, Doctor Lisa Lincz
Scheme Project Grant
Role Investigator
Funding Start 2007
Funding Finish 2007
GNo G0187243
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20061 grants / $11,000

Overcoming radiation resistance in malignant melanoma$11,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Lisa Lincz, Doctor Jennette Sakoff
Scheme Project Grant
Role Lead
Funding Start 2006
Funding Finish 2006
GNo G0186528
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20032 grants / $13,000

Investigation of mutant p53 and CD40 expression in multiple myeloma cells and response to thalidomide$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Lisa Lincz
Scheme Early Career Researcher Grant
Role Lead
Funding Start 2003
Funding Finish 2003
GNo G0182860
Type Of Funding Internal
Category INTE
UON Y

PULSE Education Prize$3,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Lisa Lincz
Scheme Research Grant
Role Lead
Funding Start 2003
Funding Finish 2003
GNo G0182735
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20011 grants / $10,000

Predicting bone marrow regeneration in cancer patients through the use of telomere quantitative (Q)-FISH$10,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Lisa Lincz, Doctor Jennette Sakoff
Scheme Lions Club of Stroud
Role Lead
Funding Start 2001
Funding Finish 2001
GNo G0181502
Type Of Funding Donation - Aust Non Government
Category 3AFD
UON Y

20002 grants / $21,500

Influence of Haematopoetic stem cell telorase activity on bone marrow recovery following myoablative therapy.$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Lisa Lincz, Ms Kerry Fagan, Doctor Jennette Sakoff
Scheme Research Grant
Role Lead
Funding Start 2000
Funding Finish 2000
GNo G0180171
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Newcastle and Hunter Junior Chamber Special Commendation Prize.$1,500

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Lisa Lincz
Scheme Research Grant
Role Lead
Funding Start 2000
Funding Finish 2000
GNo G0180172
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y
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Research Supervision

Number of supervisions

Completed2
Current2

Total current UON EFTSL

PhD0.55

Current Supervision

Commenced Level of Study Research Title / Program / Supervisor Type
2015 PhD Genomics and Pharmacogenomics of Stroke
General Medicine, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2011 PhD Investigating the Role of Microparticles in Vascular Biology and Haemostasis
General Medicine, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor

Past Supervision

Year Level of Study Research Title / Program / Supervisor Type
2013 PhD Biogenesis of Plasma CD36+Microparticles in Human Diabetes and the Metabolic Syndrome
Pharmacy, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2013 PhD Differential Effects of Long Chain Omega-3 Polyunsaturated Fatty Acids on Platelet Aggregation and Hemostatic Variables in Healthy Male Versus Female Subjects
Medical Science, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
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Dr Lisa Lincz

Position

Conjoint Senior Lecturer
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine

Focus area

Medical Biochemistry

Contact Details

Email lisa.lincz@newcastle.edu.au
Phone (02) 4921 1844
Mobile 0403492243
Fax (02) 4960 2136

Office

Room 4.28
Building Mater Hospital Level 4 - New Med 2
Location Calvary Mater Newcastle, Waratah

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