Staff Directory

Staff Profile

Career Summary

Biography

Investigations are being made on cellular rhythms including those in lymphatics, blood vessels, gastrointestinal tract, heart and specific mood-associated brain nuclei. We have discovered a new mechanism that it is driven by intracellular Ca2+ stores that allow groups of cells to self pace and hence become rhythmic. We are now exploring the relevance of this mechanism in a range of tissues. We are also interested in specific proteins involved in the pacemaker mechanism including inositol 1,4,5-trisphosphate receptors, ryanodine receptors, store operated calcium channels and TRP family proteins. These studies may influence future therapies to control lymphedema, digestive disorders, heart arrhythmias and brain mood states. We also have a recent patent relating to use of a topical ointment as a first aid treatment against snakebite. This was a surprising outcome that arose from studies investigating whether snake venoms enhance lymphatic pumping and hence accelerate their own delivery. Our preliminary trials indicate topical application of the ointment slows lymphatic transport by some 350% with no obvious adverse effects. The cream will be of particular use for bites to the torso where pressure bandaging is ineffective. It may also be useful as a first aid treatment against bites from other venomous creatures.

Qualifications

PhD, University of New South Wales
Bachelor of Engineering, University of New South Wales

Research

Research keywords

Cellular physiologist
gastrointestinal physiology
heart pacemaking
neuroscience
smooth muscle

Research expertise

Lymphatic and gastric pacemaking: Pacemaking in the lymphatic and gastric systems are the basis for our discovery of store pacemaking and calcium phase waves. We are now unravelling the finer details of these mechanisms. Importantly, as for all good research, there can often be unexpected yet important serendipitous outcomes. One in case is that this work has led to development of a first aid treatment against bites from venomous animals whose venoms transit the lymphatic system and we have a patent application on this finding under review.

Heart pacemaking: Traditionally, this has been considered to operate through a clock in the cell surface membrane of pacemaker cells. However, recent evidence from our pilot and modelling studies and from the work of others indicates a significant role of calcium stores. This introduces the possibility that the heart pacemaker model is only part of the story and that pacemaking involves an intracellular clock (i.e. store pacemaking). We are investigating this hypothesis, which if upheld will change the text book model for heart pacemaking and help change present understanding of specific heart disorders and their treatment.

(National Health and Medical Research Program Grant -NHMRC PG Cardiac Pacemaking, 2007-2009).

Brain rhythms: Brain rhythms function in most areas of the brain and while fundamental to life and our psyche remain poorly understood. We are testing the hypothesis that specific rhythms in the Locus Coeruleus, a brain stem nucleus known to be associated with mood states, are generated by store pacemaking. Evidence that the rhythms are generated by store pacemaking could provide a new framework for interpreting drug action in the treatment of mood disorders such as Bipolar Disorder.

(Australian Research Council Discovery Program Grant Investigation of a Brain Rhythm 2005-2007).

Uterine pacemaking: Astonishingly, there is still no clear understanding of the pacemaker mechanism that initiates and times uterine contractions. Pilot studies we have undertaken suggest this to be mediated by store pacemaking. Proof for this hypothesis would herald a mechanistic description for uterine contractions and may provide new insight into associated dysfunctions such as premature birth.

(NHMRC PG Rhythmicity and synchronicity in uterine smooth muscle, 2007-2009).

Fields of Research

Code	Description	Percentage
111699	Medical Physiology Not Elsewhere Classified	60
110399	Clinical Sciences Not Elsewhere Classified	30
020599	Optical Physics Not Elsewhere Classified	10

Memberships

Body relevant to professional practice.

Faculty member - Cardiovascular Physiology/Circulation of 'Faculty of 1000 Biology'
member of council - Australian Physiological society

Other

Chair, Research Committee - HMRI Cardiovascular Group
Member of Editorial Board 2001-2005 - the British Journal of Pharmacology
Member - The British Journal of Pharmacology
member - Australian Physiological Society

Appointments

Fellowship NHMRC (Australia)	01/01/2001 - 01/12/2011
NHMRC Senior Research Fellow University of Newcastle (Australia)	01/01/1990 - 01/12/2000
Senior Brawn Fellowship University of Newcastle (Australia)	01/01/1997

Awards

Honours.

2012	Honorary Member Hungarian Pharmacological Society (Australia) Honorary Member of the Hungarian Society for Clinical and Experimantl Pharmacology This was awarded because of my laboratories contributions to understanding cellular pacemaking in smooth muscle.
2007	Sparke Helmore Hunter Medical Research Institute (Australia) 2004 Hunter Medical Research Institute Sparke Helmore/ NBN Award for Research Excellence from a field of ~350 scientists in the University and Area Health Sectors

Recognition.

2013	Adjunct Professor Deaprtment of Health Innovation; Shinshu University (Japan) Invited Appontment

Invitations

calcium signaling Gordon conference, United Kingdom (Conference Presentation - non published.)	2005
Department of physiology University of Western Australia, Australia (External Reviewer - Departments.)	2005

Collaboration

Research Collaborations are being undertaken into:

1) Mechanisms underlying heart pacemaking with A/Prof Derek Laver, Prof Mark Boyett (Manchester University) and Prof Derek Terrar (Oxford University);

2) Gastrointestinal function Prof Hikaru Hashitani (Nagoya City University, Japan), Dr Bridget Southwell (Murdoch Children's Hospital) & Dr Costa Karihaloo (Lake Macquarrie Private Hospital);

3) Lymphatic function in health and disease ( Dr Mohammad Imtiaz and A/Prof Pierre Yves von der Weid (Calgary, Canada);

4) Spontaneous activity of the Locus coeruleus, a brain cell nucleus involved in establishement of attention and mood states (Dr Ramatis de Oliveira (Brazil), A/Prof Alan Brichta, Prof Robert Callister, Dr Rebecca Lim, Prof Janusz Lipski (Auckland), Mr Andrew Yee (Auckland).

Administrative

Administrative expertise

Research policy (e.g. Archetect of the Brawn Fellowship Scheme at the University of Newcastle)

Teaching

Teaching expertise

Honours and Postgraduate students

Edit

Publications

No publications.

Edit

Grants and Funding

Summary

Number of grants	82
Total funding	$8,797,754

For project grants received where the lead institution is other than the University of Newcastle, details are shown in italics.

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2013 (7 grants)

Nano-Optical Microscopy, Characterization and Fabrication Facility$155,000
Funding Body: University of Newcastle

Project Team
Doctor Andrew Fleming, Doctor John Holdsworth, Doctor Grant Webber, Professor Erich Kisi, Professor Dirk Van Helden
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$155,000	2013	2013
GNo:G1200167

HMRI MRSP Infrastructure (12-16) – CARDIOVASCULAR$118,435
Funding Body: Hunter Medical Research Institute

Project Team
Professor Dirk Van Helden, Professor Ronald Plotnikoff
Scheme		Role
MRSP Infrastructure Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$118,435	2013	2013
GNo:G1300589

Leica TP 1020 Automatic Tissue Processor for histology applications$35,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Pradeep Tanwar, Professor Eileen McLaughlin, Professor Xu Dong Zhang, Professor Robert Callister, Associate Professor Phillip Dickson, Professor Hubert Hondermarck, Doctor Jean-Marie Sontag, Professor Dirk Van Helden, Doctor Doug Smith, Doctor Phil Jobling, Associate Professor Estelle Sontag, Associate Professor Paul Tooney, Doctor Susan Hua, Doctor Janet Holt, Doctor Jay Horvat, Associate Professor Liz Milward, Professor Adam McCluskey, Associate Professor Brett Nixon, Doctor Rebecca Lim, Associate Professor Alan Brichta
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$35,000	2013	2013
GNo:G1201185

Ultra-Low Temperature Cryogenic Freezer$24,596
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Jude Weidenhofer, Doctor Rick Thorne, Doctor Kathryn Skelding, Doctor Nikki Verrills, Doctor Pradeep Tanwar, Associate Professor Phillip Dickson, Doctor Murray Cairns, Professor Hubert Hondermarck, Professor Xu Dong Zhang, Associate Professor Estelle Sontag, Doctor Chen Chen Jiang, Associate Professor Liz Milward, Doctor Jean-Marie Sontag, Associate Professor Paul Tooney, Doctor Severine Roselli, Doctor Matt Dun, Doctor Chris Dayas, Doctor Lin Kooi Ong, Professor Dirk Van Helden, Mr Ben Copeland, Ms Gabrielle Briggs, Conjoint Professor Leonie Ashman, Professor John Rostas
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$24,596	2013	2013
GNo:G1201189

Investigating the basis for diabetes-associated gastric motility disorders$10,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Dirk Van Helden
Scheme		Role
Near Miss		Chief Investigator
Total Amount	Funding Start	Funding Finish
$10,000	2013	2013
GNo:G1300701

Investigating the basis for diabetes-associated gastric motility disorders$10,000
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden, Associate Professor Derek Laver
Scheme		Role
Near Miss Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$10,000	2013	2013
GNo:G1300485

The 90th Annual Meeting of the Physiological Society of Japan, Tokyo 27-29 March 2013$1,569
Funding Body: University of Newcastle - Faculty of Health

Project Team
Professor Dirk Van Helden
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$1,569	2013	2013
GNo:G1300979

2012 (5 grants)

A novel approach to snakebite first aid$195,721
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Dirk Van Helden, Doctor Geoff Isbister
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$195,721	2012	2014
GNo:G1100333

HMRI MRSP Infrastructure (11-12)- CARDIOVASCULAR$118,434
Funding Body: Hunter Medical Research Institute

Project Team
Professor Dirk Van Helden, Professor Ronald Plotnikoff
Scheme		Role
MRSP Infrastructure Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$118,434	2012	2013
GNo:G1101118

First Aid for Cytotoxic Snakebite$25,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Dirk Van Helden, Doctor Geoff Isbister
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$25,000	2012	2013
GNo:G1200154

Gastric Slow Waves and Motility Disorders$20,000
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden, Associate Professor Derek Laver
Scheme		Role
Near Miss Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$20,000	2012	2012
GNo:G1200674

International Conference to Celebrate the 50th Anniversary of Hungarian Society for Experimental and Clinical Pharmacology, Budpest, Hungary, 19 - 21 September 2012$2,000
Funding Body: University of Newcastle - Faculty of Health

Project Team
Professor Dirk Van Helden
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2,000	2012	2013
GNo:G1200935

2011 (1 grants)

Ryanodine receptor inhibitors as therapy for Ca2+ store overload induced arrhythmias$536,706
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Derek Laver, Professor Dirk Van Helden, Associate Professor Bjorn Knollman
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$536,706	2011	2013
GNo:G1000274

2010 (3 grants)

HMRI MRSP Infrastructure Grant (10-11) - Cardiovascular$76,117
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Derek Laver, Professor Dirk Van Helden, Associate Professor Eugene Nalivaiko, Associate Professor Liz Milward, Professor Robert Callister, Professor Manohar Garg, Conjoint Professor Tony Quail
Scheme		Role
MRSP Infrastructure Grant		Investigator
Total Amount	Funding Start	Funding Finish
$76,117	2010	2011
GNo:G1100525

Effective anti-arrhythmic drugs: How do they work?$30,000
Funding Body: BellBerry Limited

Project Team
Associate Professor Derek Laver, Professor Dirk Van Helden, Associate Professor Bjorn Knollman
Scheme		Role
Near Miss		Investigator
Total Amount	Funding Start	Funding Finish
$30,000	2010	2012
GNo:G0900218

Electron Multiplier Charge-Coupled Device Camera. Hamamatsu EM-CCD Camera C9100-13$29,079
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Keith Jones, Professor Eileen McLaughlin, Professor Dirk Van Helden, Doctor Rick Thorne
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$29,079	2010	2010
GNo:G1000052

2009 (4 grants)

Electron Microscopes for Nanometer-scale Imaging/Microanalysis in the Materials, Biological, Physical, Engineering and Chemical Sciences$650,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Erich Kisi, Professor Scott Donne, Doctor Vicki Keast, Associate Professor Alan Brichta, Professor Robert Melchers, Conjoint Professor Christina Offler, Professor John O'Connor, Professor Reza Moheimani, Emeritus Professor John Patrick, Professor Dirk Van Helden, Professor Bruce King, Professor Geoffrey Evans, Professor Hugh Dunstan, Doctor Geoffrey MacFarlane, Associate Professor Yong-Ling Ruan, Doctor Severine Roselli, Doctor Minjie Lin, Professor Christopher Grof, Doctor Silvia Frisia, Doctor Rebecca Lim, Doctor Heber Sugo, Doctor Jennifer Forrester, Doctor Olivier Buzzi, Doctor Andrew Fleming, Professor Erica Wanless, Doctor Clovia Holdsworth, Doctor Russell Drysdale, Professor Stephen Fityus, Associate Professor David McCurdy, Doctor De Zhu
Scheme		Role
Linkage Infrastructure Equipment & Facilities (LIEF)		Investigator
Total Amount	Funding Start	Funding Finish
$650,000	2009	2009
GNo:G0189120

Confocal Laser Scanning Microscopy for Live Cell Imaging$275,000
Funding Body: ARC (Australian Research Council)

Project Team
Conjoint Professor Keith Jones, Professor Eileen McLaughlin, Laureate Professor John Aitken, Conjoint Professor Ray Rose, Emeritus Professor John Patrick, Conjoint Professor Christina Offler, Associate Professor David McCurdy, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Professor Dirk Van Helden, Doctor Nikki Verrills, Associate Professor Brett Nixon, Doctor Shaun Roman, Associate Professor Yong-Ling Ruan, Doctor Rick Thorne, Professor Mike Calford
Scheme		Role
Linkage Infrastructure Equipment & Facilities (LIEF)		Investigator
Total Amount	Funding Start	Funding Finish
$275,000	2009	2009
GNo:G0189038

Electron Microscopes for Nanometer-scale Imaging/Microanalysis in the Materials, Biological, Physical, Engineering and Chemical Sciences$70,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Erich Kisi, Professor Scott Donne, Doctor Vicki Keast, Associate Professor Alan Brichta, Professor Robert Melchers, Conjoint Professor Christina Offler, Professor John O'Connor, Professor Reza Moheimani, Emeritus Professor John Patrick, Professor Dirk Van Helden, Professor Bruce King, Professor Geoffrey Evans, Professor Hugh Dunstan, Doctor Geoffrey MacFarlane, Associate Professor Yong-Ling Ruan, Doctor Severine Roselli, Doctor Minjie Lin, Professor Christopher Grof, Doctor Silvia Frisia, Doctor Rebecca Lim, Doctor Heber Sugo, Doctor Jennifer Forrester, Doctor Olivier Buzzi, Doctor Andrew Fleming, Professor Erica Wanless, Doctor Clovia Holdsworth, Doctor Russell Drysdale, Professor Stephen Fityus, Associate Professor David McCurdy, Doctor De Zhu
Scheme		Role
Linkage Infrastructure Equipment & Facilities (LIEF) Partner funding		Investigator
Total Amount	Funding Start	Funding Finish
$70,000	2009	2009
GNo:G0190441

Propagation and directionality of gastric slow waves$20,000
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden, Associate Professor Derek Laver
Scheme		Role
Near Miss Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$20,000	2009	2009
GNo:G0189817

2008 (4 grants)

The effects of iron status on calcium handling systems in heart and brain$25,000
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Derek Laver, Associate Professor Liz Milward, Professor Dirk Van Helden, Professor Rodney Scott
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$25,000	2008	2008
GNo:G0188463

Colibri high-performance LED illumination system for fluorescence live cell microscopy$23,225
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Rick Thorne, Dr Charles De Bock, Professor Xu Dong Zhang, Doctor Lisa Lincz, Professor Gordon Burns, Conjoint Professor Peter Hersey, Professor Dirk Van Helden, Conjoint Professor Keith Jones, Professor Roger Smith
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$23,225	2008	2008
GNo:G0188545

Leica VT2100S Vibrating Microtome$20,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Alan Brichta, Professor Robert Callister, Professor Dirk Van Helden, Associate Professor Philip Bolton, Doctor Rebecca Lim, Doctor Brett Graham, Dr Marcus Howlett, Doctor Angela McPherson, Doctor Mohammad Imtiaz, Doctor Ramatis De Oliveira, Mr Wayne Anderson, Mr Matthew Walsh
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$20,000	2008	2008
GNo:G0188540

HMRI - Equipment Grant - High Speed Sensitivity CCD camera, centrifuge ELISA plate washer. etc$18,919
Funding Body: Hunter Medical Research Institute

Project Team
Professor Dirk Van Helden, Professor Manohar Garg
Scheme		Role
Equipment Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$18,919	2008	2008
GNo:G0189386

2007 (5 grants)

HMRI - Cardiovascular Research Program$518,556
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Derek Laver, Conjoint Professor Tony Quail, Professor Dirk Van Helden, Professor Manohar Garg, Professor Robin Callister
Scheme		Role
MRSP Infrastructure Grant		Investigator
Total Amount	Funding Start	Funding Finish
$518,556	2007	2009
GNo:G0187946

Cardiac Pacemaking$327,750
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Dirk Van Helden
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$327,750	2007	2009
GNo:G0186436

Rhythmicity and Synchronicity in Uterine Smooth Muscle$281,250
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Dirk Van Helden, Associate Professor Helena Parkington
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$281,250	2007	2009
GNo:G0186431

High speed/sensitivity CCD camera$30,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Dirk Van Helden, Professor Eileen McLaughlin, Professor Gordon Burns, Doctor Rick Thorne, Dr Marcus Howlett, Doctor Mohammad Imtiaz, Associate Professor Alan Brichta, Professor Robert Callister, Doctor Brett Graham, Associate Professor Derek Laver, Associate Professor Liz Milward, Doctor John Holdsworth
Scheme		Role
Equipment Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$30,000	2007	2007
GNo:G0188196

5th International Symposium of Interstitial Cells of Cajal, Numore, Ireland, 20/8/2007 - 23/8/2007$1,700
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$1,700	2007	2007
GNo:G0188167

2006 (2 grants)

2006 Research Fellowship$776,824
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Dirk Van Helden
Scheme		Role
Research Fellowships		Chief Investigator
Total Amount	Funding Start	Funding Finish
$776,824	2006	2011
GNo:G0185119

Mechanisms of action of w-3 fatty acids in control of atrial arrhythmias $16,000
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Derek Laver, Professor Dirk Van Helden, Doctor Bonny Honen
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$16,000	2006	2006
GNo:G0186102

2005 (4 grants)

INVESTIGATION OF A BRAIN RHYTHM$220,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Dirk Van Helden, Professor Robert Callister, Associate Professor Alan Brichta
Scheme		Role
Discovery Projects		Chief Investigator
Total Amount	Funding Start	Funding Finish
$220,000	2005	2007
GNo:G0184333

2005 RIBG allocation$20,000
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden
Scheme		Role
Research Infrastructure Block Grant (RIBG)		Chief Investigator
Total Amount	Funding Start	Funding Finish
$20,000	2005	2005
GNo:G0185808

Uterine Pacemaking$12,000
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$12,000	2005	2005
GNo:G0184693

British Physiological Society Meeting: 4th International Mammalian Myocardium Symposium, 18-20 July 2005$2,500
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2,500	2005	2005
GNo:G0185646

2004 (5 grants)

Cardiac Pacemaking$409,950
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Dirk Van Helden
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$409,950	2004	2006
GNo:G0182936

High-Speed Confocal Microscope Live Cell Recording System$274,692
Funding Body: ARC (Australian Research Council)

Project Team
Professor Dirk Van Helden, Laureate Professor John Aitken, Professor Eileen McLaughlin, Associate Professor Alan Brichta, Associate Professor J Keast, Dr J Brock, Dr S Head
Scheme		Role
Linkage Infrastructure Equipment & Facilities (LIEF)		Chief Investigator
Total Amount	Funding Start	Funding Finish
$274,692	2004	2004
GNo:G0183031

High-speed Confocal Microscope Live Cell Recording System$30,000
Funding Body: University of New South Wales

Project Team
Professor Dirk Van Helden, Associate Professor J Keast, Laureate Professor John Aitken, Dr J Brock, Professor Eileen McLaughlin, Dr S Head, Associate Professor Alan Brichta
Scheme		Role
Linkage Infrastructure Equipment & Facilities (LIEF) Partner funding		Chief Investigator
Total Amount	Funding Start	Funding Finish
$30,000	2004	2004
GNo:G0183841

Investigation a brain rythym$14,500
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden, Professor Robert Callister, Associate Professor Alan Brichta
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$14,500	2004	2004
GNo:G0184506

HMRI Award for Research Excellence$10,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Dirk Van Helden
Scheme		Role
Sparke Helmore Prime Television Corporate Triathlon Award		Chief Investigator
Total Amount	Funding Start	Funding Finish
$10,000	2004	2004
GNo:G0184891

2003 (6 grants)

CCD Camera: a Sub-Component for the High-Speed Confocal Microscope$30,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Dirk Van Helden
Scheme		Role
Equipment Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$30,000	2003	2003
GNo:G0183064

Ratiometric Ion Imaging System.$30,000
Funding Body: Ramaciotti Foundations

Project Team
Professor Dirk Van Helden
Scheme		Role
Major Equipment Award		Chief Investigator
Total Amount	Funding Start	Funding Finish
$30,000	2003	2003
GNo:G0182194

Mechanisms of action of omega-3 fatty acids in reduction of hypertension.$17,000
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Derek Laver, Professor Dirk Van Helden
Scheme		Role
Research Grant		Investigator
Total Amount	Funding Start	Funding Finish
$17,000	2003	2003
GNo:G0182641

Investigation of a Brain Rhythm$11,000
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden, Professor Robert Callister
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$11,000	2003	2003
GNo:G0182443

Visit by Dr Kayoko Hosaka 1/07/03 to 30/06/04$5,600
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden
Scheme		Role
Visitor Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$5,600	2003	2003
GNo:G0183266

British Physiological and Pharmacological Society Meeting. Manchester 9-12 Sept 2003$2,400
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2,400	2003	2003
GNo:G0183578

2002 (2 grants)

Peltier Thermal Cycler and associated equipment essential for establishing cDNA Retroviral Libraries$21,315
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Leonie Ashman, Dr Petranel Ferrao, Professor Gordon Burns, Professor Alistair Sim, Emeritus Professor Peter Dunkley, Professor John Rostas, Associate Professor Phillip Dickson, Professor Dirk Van Helden, Dr Perry Hartfield
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$21,315	2002	2002
GNo:G0181919

Role of inositol 1,4,5-trisphosphate in cellular pacemaking$13,000
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden, Professor Judith Scott
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$13,000	2002	2002
GNo:G0181329

2001 (10 grants)

Rhythmicity, synchronicity and spasm in smooth muscle.$600,285
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Dirk Van Helden
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$600,285	2001	2005
GNo:G0179698

Rhythmicity, Synchronicity and Spasm in Smooth Muscle.$543,008
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Dirk Van Helden
Scheme		Role
Research Fellowships		Chief Investigator
Total Amount	Funding Start	Funding Finish
$543,008	2001	2005
GNo:G0180718

Till Photonics Polychrome II Monochromator$16,896
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Dirk Van Helden
Scheme		Role
Equipment Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$16,896	2001	2001
GNo:G0181171

Cardiac Pacemaking.$15,000
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$15,000	2001	2001
GNo:G0180003

Mechanisms underlying cerebral vasospasm.$12,000
Funding Body: Ramaciotti Foundations

Project Team
Professor Dirk Van Helden
Scheme		Role
Research Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$12,000	2001	2001
GNo:G0179768

The effect of Defocus on the Vascular and Lymphatic System of the Avian Choroid$12,000
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden, Doctor Sally McFadden, Dr Claudia Diaz
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$12,000	2001	2001
GNo:G0180055

Thermocycler with 96 well sample block for PCR reactions. Class II Biological Safety Cabinet. Liquid Nitrogen storage Dewar & Transport Dewar$11,770
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Peter Dunkley, Professor Alistair Sim, Professor Dirk Van Helden, Professor Robert Callister
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$11,770	2001	2001
GNo:G0181178

Thermocycler with 96 well sample block for PCR reactions. Class II Biological Safety Cabinet. Liquid Nitrogen storage Dewar & Transport Dewar$11,770
Funding Body: University of Newcastle

Project Team
Emeritus Professor Peter Dunkley, Professor Alistair Sim, Professor Dirk Van Helden, Professor Robert Callister
Scheme		Role
University/NHMRC Equipment Grant Funds		Investigator
Total Amount	Funding Start	Funding Finish
$11,770	2001	2001
GNo:G0181179

Till Photonics Polychrome II Monochromator$4,896
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden
Scheme		Role
University/NHMRC Equipment Grant Funds		Chief Investigator
Total Amount	Funding Start	Funding Finish
$4,896	2001	2001
GNo:G0181172

International Union of Physiological Sciences Congress 2001, New Zealand 26 August - 2 September 2001$1,629
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$1,629	2001	2001
GNo:G0181433

2000 (2 grants)

The Physiological Basis for Spasm in Blood and Lymphatic Vessels.$19,500
Funding Body: ARC (Australian Research Council)

Project Team
Professor Dirk Van Helden
Scheme		Role
Small Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$19,500	2000	2000
GNo:G0178967

Festschrift in honour of Professor Miriam Salpeter, USA 11-12 November 2000$2,500
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2,500	2000	2000
GNo:G0180568

1999 (1 grants)

ISSMETCS Symposium of Rhythmic activity in smooth muscle, Japan$1,896
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$1,896	1999	1999
GNo:G0180521

1998 (6 grants)

The role of Calcium sparks in early muscle development$193,471
Funding Body: ARC (Australian Research Council)

Project Team
Professor Dirk Van Helden
Scheme		Role
Large Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$193,471	1998	2000
GNo:G0177119

Senior Brawn Research Support Fellowship.$80,000
Funding Body: Gladys M Brawn Memorial Fellowships

Project Team
Professor Dirk Van Helden
Scheme		Role
Postdoctoral Research Fellowship		Chief Investigator
Total Amount	Funding Start	Funding Finish
$80,000	1998	2001
GNo:G0178626

Vasomotion and Nerve-Induced Tone in the Smooth Muscle of Blood Vessels.$59,492
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden
Scheme		Role
Multi-Year Project Grant Scholarship		Chief Investigator
Total Amount	Funding Start	Funding Finish
$59,492	1998	2001
GNo:G0177264

THE ACTION OF SNAKE VENOMS ON LYMPHATIC PUMPING$15,000
Funding Body: Ramaciotti Foundations

Project Team
Professor Dirk Van Helden
Scheme		Role
Research Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$15,000	1998	1998
GNo:G0177450

Van Helden - Visit by Dr Kulmira B Nurgaliyeva$8,048
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden, Dulat Nurgaliyev
Scheme		Role
Visitor Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$8,048	1998	1998
GNo:G0177540

18th World Congress of the International Union of Angiology, Tokyo, Japan$2,400
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2,400	1998	1998
GNo:G0180618

1997 (2 grants)

Pacemaking in Smooth Muscle.$700,949
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Dirk Van Helden
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$700,949	1997	2001
GNo:G0176261

XXXIII International Congress of Physiological Sciences, Russia, 30 June - 5 July 1997$2,500
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2,500	1997	1997
GNo:G0179593

1996 (2 grants)

Electrical pacemaking in smooth muscle.$49,092
Funding Body: ARC (Australian Research Council)

Project Team
Professor Dirk Van Helden
Scheme		Role
Multi-Year Small Grant Scholarship		Chief Investigator
Total Amount	Funding Start	Funding Finish
$49,092	1996	1998
GNo:G0175832

Microscope and infra-red camera$42,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Dr Pankaj Sah, Dr B Walmsley, Emeritus Professor Peter Dunkley, Professor Dirk Van Helden
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$42,000	1996	1996
GNo:G0175473

1995 (1 grants)

The development of sensory innervation to blood vessels.$2
Funding Body: Ramaciotti Foundations

Project Team
Professor Dirk Van Helden
Scheme		Role
Research Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2	1995	1996
GNo:G0174698

1994 (2 grants)

Role of Mast Cells in Smooth Muscle Spasm$44,983
Funding Body: ARC (Australian Research Council)

Project Team
Professor Dirk Van Helden
Scheme		Role
Multi-Year Small Grant Scholarship		Chief Investigator
Total Amount	Funding Start	Funding Finish
$44,983	1994	1996
GNo:G0174826

Neurotransmitter release mechanism at the sympathetic neurovascular junction.$21,523
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Dr James Brock, Professor Dirk Van Helden
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$21,523	1994	1996
GNo:G0173006

1993 (4 grants)

Spontaneous Excitation in Lymphatic Smooth Muscle.$560,834
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Dirk Van Helden
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$560,834	1993	1997
GNo:G0173196

Control of Calcium in Neurones on the Dorsal Motor Nucleus of the Vagus.Refer A/c 43.200.948 no File opened refer s.rye 29/5/95$22,406
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Dr Pankaj Sah, Professor Dirk Van Helden
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$22,406	1993	1995
GNo:G0173188

Receptor Mechanisms Of Vascular Sensory Neurones$10,000
Funding Body: Ramaciotti Foundations

Project Team
Professor Dirk Van Helden, Dr James Brock
Scheme		Role
Research Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$10,000	1993	1993
GNo:G0173272

'XXXII Intern. Union of Physiological Sciences', Glasgow, U.K. 1-6 Aug 1993, (b) 'Symposia on Autonomic Nervous System', Oxford Univ, UK,10-14 Aug 1993$2,500
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2,500	1993	1993
GNo:G0174390

1992 (2 grants)

Role Of Sympathetic Nerves In The Development Of Hypertension$72,675
Funding Body: National Heart Foundation of Australia

Project Team
Professor Dirk Van Helden
Scheme		Role
Grant-In-Aid		Chief Investigator
Total Amount	Funding Start	Funding Finish
$72,675	1992	1993
GNo:G0173714

Mechanisms Of Activation Of Afferent Nerves On Blood Vessels$18,500
Funding Body: University of Newcastle

Project Team
Professor Dirk Van Helden
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$18,500	1992	1992
GNo:G0174237

1991 (2 grants)

Receptor Mechanisms In Vascular Smooth Muscle$60,745
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Dirk Van Helden
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$60,745	1991	1991
GNo:G0173960

The Physiological Basis For Lymphatic Pumping$11,646
Funding Body: Ramaciotti Foundations

Project Team
Professor Dirk Van Helden
Scheme		Role
Research Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$11,646	1991	1991
GNo:G0173988

Edit

Research Supervision

Number of current supervisions	4
Total current UoN PhD EFTSL	0.95

For supervisions undertaken at an institution other that the University of Newcastle, details are shown in italics, and the institution name is listed below the program name.

Current Supervision

Commenced	Proposed Completion	Program	Supervisor Type	Research Title
2012	2016	PhD (Human Physiology)	Co-Supervisor	Effects of Calmodulin on Function of Cardiac Ryanodine Receptor
2011	2015	PhD (Human Physiology)	Co-Supervisor	The Lymphatic Function in Diabetes
2010	2014	PhD (Human Physiology)	Co-Supervisor	Regulation of Store Ca2+ Release in Healthy and Failing Heart
2010	2013	PhD (Human Physiology)	Co-Supervisor	Mechanisms of Cardiac Ryanodine Receptor Inhibition by Anti Arrhythmic Drugs

Past Supervision

Year	Program	Supervisor Type	Research Title
2013	PhD (Human Physiology)	Co-Supervisor	Regulation of Cardiac Calcium Release Channels During Acute Beta-Adrenergic Stimulation
2011	PhD (Human Physiology)	Principal Supervisor	Contractile Properties of the Female Reproductive Tract
2010	PhD (Human Physiology)	Principal Supervisor	Pacemaking in Mouse Locus Coeruleus Neurons: Electrophysiological Properties, Role of Mitochondria and Development
2010	PhD (Physics)	Co-Supervisor	Design and Investigation of a Four Mirror Scan Engine Incorporating Parabolic Reflectors
2006	PhD (Human Physiology)	Principal Supervisor	Biochemical Characterisation of the Human Transient Receptor Potential Channel, TRPC4
2003	PhD (Human Physiology)	Sole Supervisor	Distribution pacemaking through coupled oscillator-based mechanisms: A basis for long-range signalling in smooth muscle
2003	PhD (Human Physiology)	Sole Supervisor	Lymphatic Vasomotion
2003	PhD (Human Physiology)	Sole Supervisor	The Effects of Specific Neurotransmitters on Vasomotion in Guinea-Pig Mesenteric Lymphatics

Edit

Professor Dirk Van Helden

Work Phone	(02) 4921 5623
Fax	(02) 4921 7406
Email	Dirk.vanHelden@newcastle.edu.au
Position	Professor School of Biomedical Sciences and Pharmacy Faculty of Health and Medicine The University of Newcastle, Australia
Focus Area	Human Physiology
Office	MS405, Medical Sciences, Callaghan University Drive Callaghan NSW 2308 Australia
URL:	www.newcastle.edu.au/profile/dirk-vanhelden

Staff Directory

Staff Profile

Career Summary

Biography

Qualifications

Research

Research keywords

Research expertise

Fields of Research

Memberships

Body relevant to professional practice.

Other

Appointments

Awards

Honours.

Recognition.

Invitations

Collaboration

Administrative

Administrative expertise

Teaching

Teaching expertise

Publications

Grants and Funding

Summary

2013 (7 grants)

Nano-Optical Microscopy, Characterization and Fabrication Facility$155,000Funding Body: University of Newcastle

HMRI MRSP Infrastructure (12-16) – CARDIOVASCULAR$118,435Funding Body: Hunter Medical Research Institute

Leica TP 1020 Automatic Tissue Processor for histology applications$35,000Funding Body: NHMRC (National Health & Medical Research Council)

Ultra-Low Temperature Cryogenic Freezer$24,596Funding Body: NHMRC (National Health & Medical Research Council)

Investigating the basis for diabetes-associated gastric motility disorders$10,000Funding Body: Hunter Medical Research Institute

Investigating the basis for diabetes-associated gastric motility disorders$10,000Funding Body: University of Newcastle

The 90th Annual Meeting of the Physiological Society of Japan, Tokyo 27-29 March 2013$1,569Funding Body: University of Newcastle - Faculty of Health

2012 (5 grants)

A novel approach to snakebite first aid$195,721Funding Body: NHMRC (National Health & Medical Research Council)

HMRI MRSP Infrastructure (11-12)- CARDIOVASCULAR$118,434Funding Body: Hunter Medical Research Institute

First Aid for Cytotoxic Snakebite$25,000Funding Body: Hunter Medical Research Institute

Gastric Slow Waves and Motility Disorders$20,000Funding Body: University of Newcastle

International Conference to Celebrate the 50th Anniversary of Hungarian Society for Experimental and Clinical Pharmacology, Budpest, Hungary, 19 - 21 September 2012$2,000Funding Body: University of Newcastle - Faculty of Health

2011 (1 grants)

Ryanodine receptor inhibitors as therapy for Ca2+ store overload induced arrhythmias$536,706Funding Body: NHMRC (National Health & Medical Research Council)

2010 (3 grants)

HMRI MRSP Infrastructure Grant (10-11) - Cardiovascular$76,117Funding Body: Hunter Medical Research Institute

Effective anti-arrhythmic drugs: How do they work?$30,000Funding Body: BellBerry Limited

Electron Multiplier Charge-Coupled Device Camera. Hamamatsu EM-CCD Camera C9100-13$29,079Funding Body: NHMRC (National Health & Medical Research Council)

2009 (4 grants)

Electron Microscopes for Nanometer-scale Imaging/Microanalysis in the Materials, Biological, Physical, Engineering and Chemical Sciences$650,000Funding Body: ARC (Australian Research Council)

Confocal Laser Scanning Microscopy for Live Cell Imaging$275,000Funding Body: ARC (Australian Research Council)

Electron Microscopes for Nanometer-scale Imaging/Microanalysis in the Materials, Biological, Physical, Engineering and Chemical Sciences$70,000Funding Body: ARC (Australian Research Council)

Propagation and directionality of gastric slow waves$20,000Funding Body: University of Newcastle

2008 (4 grants)

The effects of iron status on calcium handling systems in heart and brain$25,000Funding Body: Hunter Medical Research Institute

Colibri high-performance LED illumination system for fluorescence live cell microscopy$23,225Funding Body: NHMRC (National Health & Medical Research Council)

Leica VT2100S Vibrating Microtome$20,000Funding Body: NHMRC (National Health & Medical Research Council)

HMRI - Equipment Grant - High Speed Sensitivity CCD camera, centrifuge ELISA plate washer. etc$18,919Funding Body: Hunter Medical Research Institute

2007 (5 grants)

HMRI - Cardiovascular Research Program$518,556Funding Body: Hunter Medical Research Institute

Cardiac Pacemaking$327,750Funding Body: NHMRC (National Health & Medical Research Council)

Rhythmicity and Synchronicity in Uterine Smooth Muscle$281,250Funding Body: NHMRC (National Health & Medical Research Council)

High speed/sensitivity CCD camera$30,000Funding Body: NHMRC (National Health & Medical Research Council)

5th International Symposium of Interstitial Cells of Cajal, Numore, Ireland, 20/8/2007 - 23/8/2007$1,700Funding Body: University of Newcastle

2006 (2 grants)

2006 Research Fellowship$776,824Funding Body: NHMRC (National Health & Medical Research Council)

Mechanisms of action of w-3 fatty acids in control of atrial arrhythmias $16,000Funding Body: Hunter Medical Research Institute

2005 (4 grants)

INVESTIGATION OF A BRAIN RHYTHM$220,000Funding Body: ARC (Australian Research Council)

2005 RIBG allocation$20,000Funding Body: University of Newcastle

Uterine Pacemaking$12,000Funding Body: University of Newcastle

British Physiological Society Meeting: 4th International Mammalian Myocardium Symposium, 18-20 July 2005$2,500Funding Body: University of Newcastle

2004 (5 grants)

Cardiac Pacemaking$409,950Funding Body: NHMRC (National Health & Medical Research Council)

High-Speed Confocal Microscope Live Cell Recording System$274,692Funding Body: ARC (Australian Research Council)

High-speed Confocal Microscope Live Cell Recording System$30,000Funding Body: University of New South Wales

Investigation a brain rythym$14,500Funding Body: University of Newcastle

HMRI Award for Research Excellence$10,000Funding Body: Hunter Medical Research Institute

2003 (6 grants)

CCD Camera: a Sub-Component for the High-Speed Confocal Microscope$30,000Funding Body: NHMRC (National Health & Medical Research Council)

Ratiometric Ion Imaging System.$30,000Funding Body: Ramaciotti Foundations

Mechanisms of action of omega-3 fatty acids in reduction of hypertension.$17,000Funding Body: Hunter Medical Research Institute

Investigation of a Brain Rhythm$11,000Funding Body: University of Newcastle

Nano-Optical Microscopy, Characterization and Fabrication Facility$155,000
Funding Body: University of Newcastle

HMRI MRSP Infrastructure (12-16) – CARDIOVASCULAR$118,435
Funding Body: Hunter Medical Research Institute

Leica TP 1020 Automatic Tissue Processor for histology applications$35,000
Funding Body: NHMRC (National Health & Medical Research Council)

Ultra-Low Temperature Cryogenic Freezer$24,596
Funding Body: NHMRC (National Health & Medical Research Council)

Investigating the basis for diabetes-associated gastric motility disorders$10,000
Funding Body: Hunter Medical Research Institute

Investigating the basis for diabetes-associated gastric motility disorders$10,000
Funding Body: University of Newcastle

The 90th Annual Meeting of the Physiological Society of Japan, Tokyo 27-29 March 2013$1,569
Funding Body: University of Newcastle - Faculty of Health

A novel approach to snakebite first aid$195,721
Funding Body: NHMRC (National Health & Medical Research Council)

HMRI MRSP Infrastructure (11-12)- CARDIOVASCULAR$118,434
Funding Body: Hunter Medical Research Institute

First Aid for Cytotoxic Snakebite$25,000
Funding Body: Hunter Medical Research Institute

Gastric Slow Waves and Motility Disorders$20,000
Funding Body: University of Newcastle

International Conference to Celebrate the 50th Anniversary of Hungarian Society for Experimental and Clinical Pharmacology, Budpest, Hungary, 19 - 21 September 2012$2,000
Funding Body: University of Newcastle - Faculty of Health

Ryanodine receptor inhibitors as therapy for Ca2+ store overload induced arrhythmias$536,706
Funding Body: NHMRC (National Health & Medical Research Council)

HMRI MRSP Infrastructure Grant (10-11) - Cardiovascular$76,117
Funding Body: Hunter Medical Research Institute

Effective anti-arrhythmic drugs: How do they work?$30,000
Funding Body: BellBerry Limited

Electron Multiplier Charge-Coupled Device Camera. Hamamatsu EM-CCD Camera C9100-13$29,079
Funding Body: NHMRC (National Health & Medical Research Council)

Electron Microscopes for Nanometer-scale Imaging/Microanalysis in the Materials, Biological, Physical, Engineering and Chemical Sciences$650,000
Funding Body: ARC (Australian Research Council)

Confocal Laser Scanning Microscopy for Live Cell Imaging$275,000
Funding Body: ARC (Australian Research Council)

Electron Microscopes for Nanometer-scale Imaging/Microanalysis in the Materials, Biological, Physical, Engineering and Chemical Sciences$70,000
Funding Body: ARC (Australian Research Council)

Propagation and directionality of gastric slow waves$20,000
Funding Body: University of Newcastle

The effects of iron status on calcium handling systems in heart and brain$25,000
Funding Body: Hunter Medical Research Institute

Colibri high-performance LED illumination system for fluorescence live cell microscopy$23,225
Funding Body: NHMRC (National Health & Medical Research Council)

Leica VT2100S Vibrating Microtome$20,000
Funding Body: NHMRC (National Health & Medical Research Council)

HMRI - Equipment Grant - High Speed Sensitivity CCD camera, centrifuge ELISA plate washer. etc$18,919
Funding Body: Hunter Medical Research Institute

HMRI - Cardiovascular Research Program$518,556
Funding Body: Hunter Medical Research Institute

Cardiac Pacemaking$327,750
Funding Body: NHMRC (National Health & Medical Research Council)

Rhythmicity and Synchronicity in Uterine Smooth Muscle$281,250
Funding Body: NHMRC (National Health & Medical Research Council)

High speed/sensitivity CCD camera$30,000
Funding Body: NHMRC (National Health & Medical Research Council)

5th International Symposium of Interstitial Cells of Cajal, Numore, Ireland, 20/8/2007 - 23/8/2007$1,700
Funding Body: University of Newcastle

2006 Research Fellowship$776,824
Funding Body: NHMRC (National Health & Medical Research Council)

Mechanisms of action of w-3 fatty acids in control of atrial arrhythmias $16,000
Funding Body: Hunter Medical Research Institute

INVESTIGATION OF A BRAIN RHYTHM$220,000
Funding Body: ARC (Australian Research Council)

2005 RIBG allocation$20,000
Funding Body: University of Newcastle

Uterine Pacemaking$12,000
Funding Body: University of Newcastle

British Physiological Society Meeting: 4th International Mammalian Myocardium Symposium, 18-20 July 2005$2,500
Funding Body: University of Newcastle

Cardiac Pacemaking$409,950
Funding Body: NHMRC (National Health & Medical Research Council)

High-Speed Confocal Microscope Live Cell Recording System$274,692
Funding Body: ARC (Australian Research Council)

High-speed Confocal Microscope Live Cell Recording System$30,000
Funding Body: University of New South Wales

Investigation a brain rythym$14,500
Funding Body: University of Newcastle

HMRI Award for Research Excellence$10,000
Funding Body: Hunter Medical Research Institute

CCD Camera: a Sub-Component for the High-Speed Confocal Microscope$30,000
Funding Body: NHMRC (National Health & Medical Research Council)

Ratiometric Ion Imaging System.$30,000
Funding Body: Ramaciotti Foundations

Mechanisms of action of omega-3 fatty acids in reduction of hypertension.$17,000
Funding Body: Hunter Medical Research Institute

Investigation of a Brain Rhythm$11,000
Funding Body: University of Newcastle

Visit by Dr Kayoko Hosaka 1/07/03 to 30/06/04$5,600
Funding Body: University of Newcastle

British Physiological and Pharmacological Society Meeting. Manchester 9-12 Sept 2003$2,400
Funding Body: University of Newcastle

Peltier Thermal Cycler and associated equipment essential for establishing cDNA Retroviral Libraries$21,315
Funding Body: NHMRC (National Health & Medical Research Council)

Role of inositol 1,4,5-trisphosphate in cellular pacemaking$13,000
Funding Body: University of Newcastle

Rhythmicity, synchronicity and spasm in smooth muscle.$600,285
Funding Body: NHMRC (National Health & Medical Research Council)

Rhythmicity, Synchronicity and Spasm in Smooth Muscle.$543,008
Funding Body: NHMRC (National Health & Medical Research Council)

Till Photonics Polychrome II Monochromator$16,896
Funding Body: NHMRC (National Health & Medical Research Council)

Cardiac Pacemaking.$15,000
Funding Body: University of Newcastle

Mechanisms underlying cerebral vasospasm.$12,000
Funding Body: Ramaciotti Foundations

The effect of Defocus on the Vascular and Lymphatic System of the Avian Choroid$12,000
Funding Body: University of Newcastle

Thermocycler with 96 well sample block for PCR reactions. Class II Biological Safety Cabinet. Liquid Nitrogen storage Dewar & Transport Dewar$11,770
Funding Body: NHMRC (National Health & Medical Research Council)

Thermocycler with 96 well sample block for PCR reactions. Class II Biological Safety Cabinet. Liquid Nitrogen storage Dewar & Transport Dewar$11,770
Funding Body: University of Newcastle

Till Photonics Polychrome II Monochromator$4,896
Funding Body: University of Newcastle

International Union of Physiological Sciences Congress 2001, New Zealand 26 August - 2 September 2001$1,629
Funding Body: University of Newcastle

The Physiological Basis for Spasm in Blood and Lymphatic Vessels.$19,500
Funding Body: ARC (Australian Research Council)

Festschrift in honour of Professor Miriam Salpeter, USA 11-12 November 2000$2,500
Funding Body: University of Newcastle

ISSMETCS Symposium of Rhythmic activity in smooth muscle, Japan$1,896
Funding Body: University of Newcastle

The role of Calcium sparks in early muscle development$193,471
Funding Body: ARC (Australian Research Council)

Senior Brawn Research Support Fellowship.$80,000
Funding Body: Gladys M Brawn Memorial Fellowships

Vasomotion and Nerve-Induced Tone in the Smooth Muscle of Blood Vessels.$59,492
Funding Body: University of Newcastle

THE ACTION OF SNAKE VENOMS ON LYMPHATIC PUMPING$15,000
Funding Body: Ramaciotti Foundations

Van Helden - Visit by Dr Kulmira B Nurgaliyeva$8,048
Funding Body: University of Newcastle

18th World Congress of the International Union of Angiology, Tokyo, Japan$2,400
Funding Body: University of Newcastle

Pacemaking in Smooth Muscle.$700,949
Funding Body: NHMRC (National Health & Medical Research Council)

XXXIII International Congress of Physiological Sciences, Russia, 30 June - 5 July 1997$2,500
Funding Body: University of Newcastle

Electrical pacemaking in smooth muscle.$49,092
Funding Body: ARC (Australian Research Council)

Microscope and infra-red camera$42,000
Funding Body: NHMRC (National Health & Medical Research Council)

The development of sensory innervation to blood vessels.$2
Funding Body: Ramaciotti Foundations

Role of Mast Cells in Smooth Muscle Spasm$44,983
Funding Body: ARC (Australian Research Council)

Neurotransmitter release mechanism at the sympathetic neurovascular junction.$21,523
Funding Body: NHMRC (National Health & Medical Research Council)

Spontaneous Excitation in Lymphatic Smooth Muscle.$560,834
Funding Body: NHMRC (National Health & Medical Research Council)

Control of Calcium in Neurones on the Dorsal Motor Nucleus of the Vagus.Refer A/c 43.200.948 no File opened refer s.rye 29/5/95$22,406
Funding Body: NHMRC (National Health & Medical Research Council)

Receptor Mechanisms Of Vascular Sensory Neurones$10,000
Funding Body: Ramaciotti Foundations

'XXXII Intern. Union of Physiological Sciences', Glasgow, U.K. 1-6 Aug 1993, (b) 'Symposia on Autonomic Nervous System', Oxford Univ, UK,10-14 Aug 1993$2,500
Funding Body: University of Newcastle

Role Of Sympathetic Nerves In The Development Of Hypertension$72,675
Funding Body: National Heart Foundation of Australia

Mechanisms Of Activation Of Afferent Nerves On Blood Vessels$18,500
Funding Body: University of Newcastle