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Dr Bente Talseth-Palmer

Cancer Institute ECR Fellow

School of Biomedical Sciences and Pharmacy (Medical Genetics)

Career Summary

Biography

Dr Talseth-Palmer was awarded her PhD in January 2008, which was undertaken in the HMRI's NBN Telethon Childhood Cancer research laboratory. She was awarded the research higher degree award for excellence in the Faculty of Health in recognition of outstanding research achievement for her Doctor of Philosophy research thesis. In January 2008, she successfully obtained a Gladys M. Brawn Memorial Post-Doctoral fellowship from the University of Newcastle and is now a part of the HMRI's, Information-Based Medicine Research Program. Prior to completing her PhD, Dr Talseth-Palmer completed a Bachelor of Medical Laboratory Technology in Norway in 1999 and a Masters of Genetic Counselling at the University of Newcastle in 2004. Between 1999 and 2003, Dr Talseth-Palmer worked as a research assistant focusing on genetic research both in Iceland and Norway. In 2006, Dr Talseth-Palmer was awarded a travel grant to attend the 11th International Congress of Human Genetics by the Human Genetics Society of Australasia (HGSA). In 2008, she was nominated as 10 of the best research showcases at the University of Newcastle and, in 2009, she was awarded the Hunter Medical Research Institute (HMRI) Pulse Education Prize, an award presented to outstanding early career researchers. Dr Talseth-Palmer is also an invited reviewer for the journal, Cancer Causes & Control.

Research Expertise
- Single Nucleotide Polymorphisms (SNPs) - Modifier genes - Genetic variation - Hereditary Non-Polyposis Colorectal Cancer (HNPCC) - Acute Lymphoblastic Leukaemia (ALL) - Genome-wideSNP array technology

Collaborations
Dr Talseth-Palmer is currently collaborating in several international studies: HNPCC, Juul Wijnen, LUMC, the Netherlands; MOMA study, Malcolm Dunlop, MRC, UK; 6-SNP collaboration, Annika Lindblom, Karolinska Institute, Sweden; and Modifier genes in HNPCC, Jan Lubinski, International Hereditary Cancer Center, Poland.


Qualifications

  • Doctor of Philosophy, University of Newcastle
  • Master of Genetic Counselling, University of Newcastle

Keywords

  • Acute Lymphoblastic Leukaemia (ALL)
  • Genetic variation
  • Genome-wideSNP array technology
  • Hereditary Non-Polyposis Colorectal Cancer (HNPCC)
  • Honours supervision
  • Modifier genes
  • Single Nucleotide Polymorphisms (SNPs)

Languages

  • English (Fluent)
  • Norwegian (Fluent)

Fields of Research

CodeDescriptionPercentage
060499Genetics not elsewhere classified50
111799Public Health and Health Services not elsewhere classified10
111299Oncology and Carcinogenesis not elsewhere classified40

Professional Experience

UON Appointment

DatesTitleOrganisation / Department
1/01/2015 - 31/12/2018Cancer Institute ECR FellowUniversity of Newcastle
School of Biomedical Sciences and Pharmacy
Australia
26/07/2010 - 12/11/2010Casual LecturerUniversity of Newcastle
School of Biomedical Sciences and Pharmacy
Australia

Academic appointment

DatesTitleOrganisation / Department
1/01/2011 - 1/12/2014NHMRC Training (Post-Doctoral) Fellow
NHMRC - Australia Fellowship (Formerly Australia Fellowship Scheme)
University of Newcastle
Australia
1/01/2009 - Membership - The Australasian Microarray & Associated Technologies Association (AMATA)The Australasian Microarray & Associated Technologies Association (AMATA)
Australia
1/01/2008 - 1/12/2010Glady's M. Brawn Memorial Post-Doctoral FellowUniversity of Newcastle
Australia
1/01/2008 - Membership - Hunter Children's Research Executive (HCRE) Subcommittee Hunter Childrens Research Executive (HCRE) Subcommittee
Australia
1/01/2008 - Brawn Post Doc FellowUniversity of Newcastle
Australia
1/01/2007 - 31/12/2008Membership - Business & Professional Woman (BPW) AustraliaBusiness & Professional Woman (BPW) Australia
Australia
1/01/2007 - Membership - Australian Society for Medical Research (ASMR)The Australian Society for Medical Research
1/01/2003 - Membership - Human Genetics Society of Australasia (HGSA)Human Genetics Society of Australasia (HGSA)
Australia
1/05/2000 - 1/12/2002Research AssistantUniversity of Oslo
Norway
1/07/1999 - 1/05/2000Research AssistantIceland Genomic Corporation
Iceland

Professional appointment

DatesTitleOrganisation / Department
1/06/2004 - 1/09/2004Genetic CounsellorHunter New England Health
Australia

Awards

Recipient

YearAward
2008Higher degree excellence
University of Newcastle
2004NBN Telethon Childhood Cancer PhD Scholarship
University of Newcastle

Research Award

YearAward
2009Hunter Medical Research Institute (HMRI) Pulse Education Prize
Unknown
2008Poster prize
Unknown
2006Travel grant
Human Genetics Society of Australasia (HGSA)
2005Cancer Institute NSW Research Scholar Award
Cancer Institute NSW
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (1 outputs)

YearCitationAltmetricsLink
2012Scott R, Reeves SG, Talseth-Palmer B, 'The role of modifier genes in Lynch Syndrome', Colorectal Cancer Biology From Genes To Tumor, InTech, Slovenia 37-58 (2012) [B1]
DOI10.5772/1163
Co-authorsBente Talseth-Palmer, Rodney Scott

Journal article (29 outputs)

YearCitationAltmetricsLink
2014Evans TJ, Milne E, Anderson D, de Klerk NH, Jamieson SE, Talseth-Palmer BA, et al., 'Confirmation of childhood acute lymphoblastic leukemia variants, ARID5B and IKZF1, and interaction with parental environmental exposures.', PLoS One, 9 e110255 (2014) [C1]
DOI10.1371/journal.pone.0110255Author URL
CitationsScopus - 1Web of Science - 1
Co-authorsLiz Holliday, Bente Talseth-Palmer, Rodney Scott, John Attia, Nikola Bowden
2014Masson AL, Talseth-Palmer BA, Evans T-J, Grice DM, Hannan GN, Scott RJ, 'Expanding the genetic basis of copy number variation in familial breast cancer', Hereditary Cancer in Clinical Practice, 12 (2014) [C1]

Introduction: Familial breast cancer (fBC) is generally associated with an early age of diagnosis and a higher frequency of disease among family members. Over the past two decades... [more]

Introduction: Familial breast cancer (fBC) is generally associated with an early age of diagnosis and a higher frequency of disease among family members. Over the past two decades a number of genes have been identified that are unequivocally associated with breast cancer (BC) risk but there remain a significant proportion of families that cannot be accounted for by these genes. Copy number variants (CNVs) are a form of genetic variation yet to be fully explored for their contribution to fBC. CNVs exert their effects by either being associated with whole or partial gene deletions or duplications and by interrupting epigenetic patterning thereby contributing to disease development. CNV analysis can also be used to identify new genes and loci which may be associated with disease risk.Methods: The Affymetrix Cytogenetic Whole Genome 2.7 M (Cyto2.7 M) arrays were used to detect regions of genomic re-arrangement in a cohort of 129 fBC BRCA1/BRCA2 mutation negative patients with a young age of diagnosis (<50 years) compared to 40 unaffected healthy controls (>55 years of age).Results: CNV analysis revealed the presence of 275 unique rearrangements that were not present in the control population suggestive of their involvement in BC risk. Several CNVs were found that have been previously reported as BC susceptibility genes. This included CNVs in RPA3, NBN (NBS1), MRE11A and CYP19A1 in five unrelated fBC patients suggesting that these genes are involved in BC initiation and/or progression. Of special interest was the identification of WWOX and FHIT rearrangements in three unrelated fBC patients.Conclusions: This study has identified a number of CNVs that potentially contribute to BC initiation and/or progression. The identification of CNVs that are associated with known tumour suppressor genes is of special interest that warrants further larger studies to understand their precise role in fBC. © 2014 Masson et al.; licensee BioMed Central Ltd.

DOI10.1186/1897-4287-12-15
Co-authorsBente Talseth-Palmer, Rodney Scott
2013Masson AL, Talseth-Palmer BA, Evans T-J, Grice DM, Duesing K, Hannan GN, Scott RJ, 'Copy number variation in hereditary non-polyposis colorectal cancer', Genes, 4 536-555 (2013) [C1]
DOI10.3390/genes4040536
Co-authorsRodney Scott, Bente Talseth-Palmer
2013Talseth-Palmer BA, Wijnen JT, Barker D, Vasen HFA, Scott RJ, 'Is the reported modifying effect of 8q23.3 and 11q23.1 on colorectal cancer risk for MLH1 mutation carriers valid? Reply', INTERNATIONAL JOURNAL OF CANCER, 133 1764-1764 (2013) [C3]
DOI10.1002/ijc.28178Author URL
Co-authorsBente Talseth-Palmer, Rodney Scott
2013Talseth-Palmer B, Wijnen JT, Brenne IS, Jagmohan-Changur S, Barker DJ, Ashton KA, et al., 'Combined analysis of three Lynch syndrome cohorts confirms the modifying effects of 8q23.3 and 11q23.1 in MLH1 mutation carriers', International Journal of Cancer, 132 1487-1729 (2013) [C1]
CitationsScopus - 6Web of Science - 7
Co-authorsRodney Scott, Katie Ashton, Bente Talseth-Palmer
2013Chen J, Pande M, Huang Y-J, Wei C, Amos CI, Talseth-Palmer BA, et al., 'Cell cycle-related genes as modifiers of age of onset of colorectal cancer in Lynch syndrome: a large-scale study in non-Hispanic white patients', CARCINOGENESIS, 34 299-306 (2013) [C1]
DOI10.1093/carcin/bgs344Author URL
CitationsScopus - 3Web of Science - 3
Co-authorsBente Talseth-Palmer, Rodney Scott
2013Talseth-Palmer BA, Wijnen JT, Grice DM, Scott RJ, 'Genetic modifiers of cancer risk in Lynch syndrome: a review', FAMILIAL CANCER, 12 207-216 (2013) [C1]
DOI10.1007/s10689-013-9614-2Author URL
CitationsScopus - 3Web of Science - 2
Co-authorsRodney Scott, Bente Talseth-Palmer
2013Talseth-Palmer BA, Wijnen JT, Andreassen EK, Barker D, Jagmohan-Changur S, Tops CM, et al., 'The importance of a large sample cohort for studies on modifier genes influencing disease severity in FAP patients.', Hered Cancer Clin Pract, 11 20 (2013) [C1]
DOI10.1186/1897-4287-11-20Author URL
CitationsScopus - 1Web of Science - 1
Co-authorsBente Talseth-Palmer, Rodney Scott
2013Talseth-Palmer B, Holliday EG, Evans T-J, McEvoy MA, Attia JR, Grice DM, et al., 'Continuing difficulties in interpreting CNV data: Lessons from a genome-wide CNV association study of Australian HNPCC/lynch syndrome patients', BMC Medical Genomics, 6 1-13 (2013) [C1]
CitationsScopus - 3Web of Science - 3
Co-authorsJohn Attia, Liz Holliday, Bente Talseth-Palmer, Rodney Scott
2013Picelli S, Lorenzo Bermejo J, Chang-Claude J, Hoffmeister M, Fernandez-Rozadilla C, Carracedo A, et al., 'Meta-Analysis of Mismatch Repair Polymorphisms within the Cogent Consortium for Colorectal Cancer Susceptibility', PLOS ONE, 8 (2013) [C1]
DOI10.1371/journal.pone.0072091Author URL
CitationsScopus - 3Web of Science - 3
Co-authorsRodney Scott, Bente Talseth-Palmer
2012Talseth-Palmer B, Scott R, Vasen HFA, Wijnen JT, '8q23.3 and 11q23.1 as modifying loci influencing the risk for CRC in Lynch syndrome', European Journal of Human Genetics, 20 487-488 (2012) [C3]
CitationsScopus - 2Web of Science - 2
Co-authorsBente Talseth-Palmer, Rodney Scott
2011Kiejda KA, Bowden NA, Croft AJ, Scurr LL, Kairupan CF, Ashton KA, et al., 'P53 in human melanoma fails to regulate target genes associated with apoptosis and the cell cycle and may contribute to proliferation', BMC Cancer, 11 203-219 (2011) [C1]
DOI10.1186/1471-2407-11-203
CitationsScopus - 28Web of Science - 21
Co-authorsKatie Ashton, Bente Talseth-Palmer, Kelly Kiejda, Rodney Scott, Nikola Bowden, Xu Zhang
2011Talseth-Palmer B, Scott R, 'Genetic variation and its role in malignancy', International Journal of Biomedical Science, 7 158-171 (2011) [C1]
CitationsScopus - 1
Co-authorsRodney Scott, Bente Talseth-Palmer
2011Talseth-Palmer B, Brenne IS, Ashton KA, Evans T-J, McPhillips M, Groombridge C, et al., 'Colorectal cancer susceptibility loci on chromosome 8q23.3 and 11q23.1 as modifiers for disease expression in lynch syndrome', Journal of Medical Genetics, 48 279-284 (2011) [C1]
DOI10.1136/jmg.2010.079962
CitationsScopus - 25Web of Science - 20
Co-authorsRodney Scott, Katie Ashton, Bente Talseth-Palmer
2011Wong-Brown M, Nordfors C, Mossman D, Pecenpetelovska G, Kiejda KA, Talseth-Palmer B, et al., 'BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer', Breast Cancer Research and Treatment, 127 853-859 (2011) [C1]
DOI10.1007/s10549-011-1443-0
CitationsScopus - 39Web of Science - 37
Co-authorsRodney Scott, Kelly Kiejda, Michelle Wong-Brown, Bente Talseth-Palmer, Nikola Bowden
2010Talseth-Palmer B, McPhillips M, Groombridge C, Spigelman A, Scott R, 'MSH6 and PMS2 mutation positive Australian Lynch syndrome families: Novel mutations, cancer risk and age of diagnosis of colorectal cancer', Hereditary Cancer in Clinical Practice, 8 1-10 (2010) [C1]
DOI10.1186/1897-4287-8-5
CitationsScopus - 10Web of Science - 9
Co-authorsBente Talseth-Palmer, Rodney Scott
2009Shi Z, Johnstone DM, Talseth-Palmer B, Evans T-J, Spigelman AD, Groombridge C, et al., 'Haemochromatosis HFE gene polymorphisms as potential modifiers of hereditary nonpolyposis colorectal cancer risk and onset age', International Journal of Cancer, 125 78-83 (2009) [C1]
DOI10.1002/ijc.24304
Co-authorsRodney Scott, Liz Milward, Bente Talseth-Palmer
2009Talseth-Palmer B, Bowden NA, Meldrum C, Nicholl J, Thompson E, Friend K, et al., 'A 1q44 deletion, paternal UPD of chromosome 2 and a deletion due to a complex translocation detected in children with abnormal phenotypes using new SNP array technology', Cytogenetic and Genome Research, 124 94-101 (2009) [C1]
DOI10.1159/000200093
CitationsScopus - 4Web of Science - 4
Co-authorsNikola Bowden, Rodney Scott, Bente Talseth-Palmer
2008Talseth-Palmer B, Bowden NA, Hill A, Meldrum C, Scott R, 'Whole genome amplification and its impact on CGH array profiles', BMC Research Notes, 1 108 (2008) [C1]
DOI10.1186/1756-0500-1-56
CitationsScopus - 11
Co-authorsNikola Bowden, Bente Talseth-Palmer, Rodney Scott
2008Talseth-Palmer B, Ashton KA, Meldrum C, Suchy J, Kurzawski G, Lubinski J, Scott R, 'Aurora-A and Cyclin D1 polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer', International Journal of Cancer, 122 1273-1277 (2008) [C1]
DOI10.1002/ijc.23177
CitationsScopus - 22Web of Science - 18
Co-authorsBente Talseth-Palmer, Katie Ashton, Rodney Scott
2007Talseth-Palmer B, Meldrum C, Suchy J, Kurzawski G, Lubinski J, Scott R, 'MDM2 SNP309 T > G alone or in combination with the TP53 R72P polymorphism does not appear to influence disease expression and age of diagnosis of colorectal cancer in HNPCC patients', International Journal of Cancer, 120 563-565 (2007) [C1]
DOI10.1002/ijc.22339
CitationsScopus - 27Web of Science - 28
Co-authorsRodney Scott, Bente Talseth-Palmer
2007Talseth-Palmer B, Meldrum C, Suchy J, Kurzawski G, Lubinski J, Scott R, 'Lack of association between genetic polymorphisms in cytokine genes and disease expression in patients with hereditary non-polyposis colorectal cancer', Scandinavian Journal of Gastroenterology, 42 628-632 (2007) [C1]
DOI10.1080/00365520601106699
CitationsScopus - 10Web of Science - 9
Co-authorsBente Talseth-Palmer, Rodney Scott
2006Talseth-Palmer B, Meldrum C, Suchy J, Kurzawski G, Lubinski J, Scott R, 'Age of diagnosis of colorectal cancer in HNPCC patients is more complex than that predicted by R72P polymorphism in TP53', International Journal of Cancer, 118 2479-2484 (2006) [C1]
DOI10.1002/ijc.21661
CitationsScopus - 25Web of Science - 22
Co-authorsBente Talseth-Palmer, Rodney Scott
2006Talseth-Palmer B, Meldrum C, Suchy J, Kurzawski G, Lubinski J, Scott R, 'Genetic polymorphisms in xenobiotic clearance genes and their influence on disease expression in hereditary nonpolyposis colorectal cancer patients', Cancer Epidemiology Biomarkers & Prevention, 15 2307-2310 (2006) [C1]
DOI10.1158/1055-9965.EPI-06-0040
CitationsScopus - 16Web of Science - 13
Co-authorsBente Talseth-Palmer, Rodney Scott
2003Louka AS, Lie BA, Talseth B, Ascher H, Ek J, Gudjonsdottir AH, Sollid LM, 'Coeliac disease patients carry conserved HLA-DR3-DQ2 haplotypes revealed by association of TNF alleles', Immunogenetics, 55 339-343 (2003) [C1]
DOI10.1007/s00251-003-0586-5
CitationsScopus - 24Web of Science - 24
Co-authorsBente Talseth-Palmer
2003Louka AS, Moodie SJ, Karell K, Bolognesi E, Ascher H, Greco L, et al., 'A collaborative European search for non-DQA1 *05-DQB1 *02 Celiac disease loci on HLA-Dr3 haplotypes: Analysis of transmission from homozygous parents', Human Immunology, 64 350-358 (2003)

The HLA-DQA1 *05 with DQB1 *02 alleles are a major risk factor for celiac disease (CD). To search for additional human leukocyte antigen (HLA) risk factors, we looked on the DR3-D... [more]

The HLA-DQA1 *05 with DQB1 *02 alleles are a major risk factor for celiac disease (CD). To search for additional human leukocyte antigen (HLA) risk factors, we looked on the DR3-DQ2 risk haplotype, selected because it carries both DQ risk alleles in cis and is the more represented among CD patients. In a European consortium, we identified 109 families with a parent homozygous for DQA1 *05-DQB1 *02. We typed ten microsatellites in the extended HLA complex, and applied the homozygous-parent transmission disequilibrium test (HPTDT) and extended-TDT to transmissions from homozygous parents. These methods eliminate confounding due to linkage disequilibrium between candidate disease loci and the known risk factor DQA1 *05-DQB1 *02, and are favorable when sufficient families are available. We did not find evidence of association with any single market or allele, although weak evidence for additional risk was observed, represented by preferential transmission of six adjacent markers. We tested the largest ever reported HPTDT population in CD, providing unprecedented power. We did not find significant evidence of additional risk-modifying factors on the DR3 haplotype, independent of DQA1 *05-DQB1 *02, although a weak tendency was observed for the B8-DR3 haplotype. This effect should be tested in large populations with significant representations of both B8-DR3 and non-B8 DR3 haplotypes. © American Society for Histocompatibility and Immunogenetics, 2003. Published by Elsevier Science Inc.

DOI10.1016/S0198-8859(02)00822-4
CitationsScopus - 20
Co-authorsBente Talseth-Palmer
2003Babron M-C, Nilsson S, Adamovic S, Naluai ÅT, Wahlström J, Ascher H, et al., 'Meta and pooled analysis of European coeliac disease data', European Journal of Human Genetics, 11 828-834 (2003)

Four full genome scans have been carried out by the partners of the European cluster on coeliac disease as well as follow-up studies of candidate regions. No region outside HLA sh... [more]

Four full genome scans have been carried out by the partners of the European cluster on coeliac disease as well as follow-up studies of candidate regions. No region outside HLA showed significant linkage to the disease in any single study. We first applied a meta-analysis based on a modification of Genome Screen Meta-Analysis to take into account the different linkage statistics, the arbitrariness of bin cutoff points, as well as the sample size of each study. We then performed a pooled linkage analysis of all families and raw genotypes. Besides the HLA region, already known to harbour a risk factor for coeliac disease, both approaches leave very little doubt on the presence of a genetic risk factor in the 5q31-33 region. This region was suggested by several individual studies, but did not reach statistical values high enough to be conclusive when data sets were analysed separately.

DOI10.1038/sj.ejhg.5201051
CitationsScopus - 70
Co-authorsBente Talseth-Palmer
2002Louka A, Nilsson S, Olsson M, Talseth B, Lie B, Ek J, et al., 'HLA in coeliac disease families: a novel test of risk modification by the 'other' haplotype when at least one DQA1*05-DQB1*02 haplotype is carried. (2002) [C1]
CitationsScopus - 35Web of Science - 34
Co-authorsBente Talseth-Palmer
2001Kristinsson S, Thorolfsdottir E, Talseth B, Steingrimsson E, Thorsson A, Helgason T, et al., 'MODY in Iceland is associated with mutations in HNF-1alpha and a novel mutation in NeuroD1. (2001) [C1]
CitationsScopus - 56Web of Science - 48
Co-authorsBente Talseth-Palmer
Show 26 more journal articles

Conference (21 outputs)

YearCitationAltmetricsLink
2014Talseth-Palmer BA, Evans TJ, Spigelman A, Scott RJ, 'Targeted next-generation sequencing - Identification of Lynch syndrome cases', EUROPEAN JOURNAL OF CANCER (2014) [E3]
Author URL
Co-authorsRodney Scott, Bente Talseth-Palmer
2013Talseth-Palmer B, Meldrum C, Ashton KA, Spigelman A, Scott RJ, 'Revealing cancer complexity - Identification of Lynch syndrome cases', Familial Cancer, Carins, QLD (2013) [E3]
Co-authorsBente Talseth-Palmer, Katie Ashton, Rodney Scott
2013Talseth-Palmer B, Wijnen JT, Andreassen EK, Jagmohan-Changur S, Barker D, Tops CM, et al., 'The importance of a large sample cohort for studies on modifier genes influencing disease development in FAP patients', Familial Cancer, Carins, QLD (2013) [E3]
Co-authorsRodney Scott, Bente Talseth-Palmer
2012Talseth-Palmer B, Scott R, 'A step closer to personalised medicine for Lynch Syndrome patients - Personalised screening can prevent cancer development in MLH1 mutation carriers', BDC 2012. 2nd Biomarker Discovery Conference, Shoal Bay, NSW (2012) [E3]
Co-authorsBente Talseth-Palmer, Rodney Scott
2012Talseth-Palmer B, Wijen J, Brenne I, Jagomohan-Changur S, Baker D, Ashton KA, et al., 'Colorectal cancer risk modification in Lynch syndrome', Human Genome Meeting 2012: Genetics and Genomics in Personalised Medicine. Abstract Book, Sydney, NSW (2012) [E3]
Co-authorsKatie Ashton, Bente Talseth-Palmer, Rodney Scott
2012Talseth-Palmer B, Holliday EG, Evans T-J, McEvoy MA, Attia JR, Grice DM, et al., 'A genome-wide CNV association study of Australian HNPCC/Lynch syndrome patients', Proceedings of the Australian Health & Medical Research Congress 2012, Adelaide, SA (2012) [E3]
Co-authorsJohn Attia, Liz Holliday, Rodney Scott, Bente Talseth-Palmer
2011Talseth-Palmer B, Wijnen JT, Brenne IS, Jagmohan-Changur S, Ashton KA, Tops CM, et al., 'Chromosome 8q23.3, 10p14 and 11q23.1 variants modify colorectal cancer risk in Lynch syndrome - a combined analysis of the Australian, Dutch and Polish Lynch syndrome cohorts', Familial Aspects of Cancer: Research and Practice 2011, Kingscliff, NSW (2011) [E3]
Co-authorsRodney Scott, Katie Ashton, Bente Talseth-Palmer
2011Talseth-Palmer B, Wijnen JT, Brenne IS, Jagmohan-Changur S, Ashton KA, Tops CM, et al., 'Chromosome 8q23.3 AND 11q23.1 variants modify colorectal cancer risk in Lynch syndrome: A meta-analysis of the Dutch and Australian Lynch syndrome cohorts', Abstracts: 4th Biennial Meeting: International Society for Gastrointestinal Hereditary Tumours, San Antonio, TX (2011) [E3]
Co-authorsRodney Scott, Bente Talseth-Palmer, Katie Ashton
2011Martin AL, Talseth-Palmer B, Grice DM, Hannan G, Scott R, 'Elucidating the genetic predisposition to colorectal cancer', XIX NSW Scientific Meeting. Programme, Sydney, NSW (2011) [E3]
Co-authorsBente Talseth-Palmer, Rodney Scott
2010Talseth-Palmer B, Holliday EG, Evans T-J, McPhillips M, Groombridge C, Spigelman AD, Scott R, 'Modifier genes influencing breast cancer incidence in HNPCC/Lynch syndrome', AMATA 2010 Conference: Conference Handbook, Hobart, Tasmania (2010) [E3]
Co-authorsLiz Holliday, Rodney Scott, Bente Talseth-Palmer
2010Scott R, Talseth-Palmer B, Reeves SG, Meldrum, Groombridge C, Spigelman AD, et al., 'MTHFR 677 C>T and 1298 A>C polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer', Familial Cancer, Dusseldorf, Germany (2010) [E3]
DOI10.1038/ejhg.2008.239
CitationsScopus - 11Web of Science - 11
Co-authorsBente Talseth-Palmer, Rodney Scott
2010Talseth-Palmer B, McPhillips M, Meldrum C, Groombridge C, Spigelman AD, Scott R, 'Hereditary nonpolyposis colorectal cancer in 688 families: Mutations, age of diagnosis and cancer incidence', Familial Cancer, Dusseldorf, Germany (2010) [E3]
Co-authorsRodney Scott, Bente Talseth-Palmer
2010Talseth-Palmer B, McPhillips M, Meldrum C, Groombridge C, Spigelman AD, Scott R, 'Haemochromatosis HFE gene polymorphisms as ptential modifiers of hereditary nonpolyposis colorectal cancer risk and onset age', Familial Cancer, Dusseldorf, Germany (2010) [E3]
CitationsScopus - 16Web of Science - 13
Co-authorsBente Talseth-Palmer, Rodney Scott
2010Evans T-J, Talseth-Palmer B, Brenne IS, Ashton KA, McPhillips M, Groombridge C, et al., 'Colorectal cancer suspectibility loci on chr 8q23.3 and 11q23.1 as modifiers for disease expression in Lynch syndrome', Sydney Cancer Conference 2010. Profiling Risk, Personalising Treatment and Predicting Outcomes. Conference Program and Abstract Book, Sydney, NSW (2010) [E3]
Co-authorsRodney Scott, Katie Ashton, Bente Talseth-Palmer
2010Talseth-Palmer BA, Brenne IS, Ashton K, Evans TJ, McPhillips M, Groombridge C, et al., 'Colorectal cancer susceptibility loci on chr 8q23.3 and 11q23.1 as modifiers for disease expression in Lynch syndrome', EJC SUPPLEMENTS, Oslo, NORWAY (2010) [E3]
Author URL
Co-authorsRodney Scott, Bente Talseth-Palmer
2010Talseth-Palmer B, Holliday EG, Evans T-J, McPhillips M, McEvoy MA, Attia JR, Scott R, 'A modern approach to the search for modifying genetic loci infleuncing the high breast cancer incidence seen in an Australian HNPCC/Lynch Syndrome cohort', Proceedings of the Australian Health and Medical Research Congress 2010, Melbourne, Vic (2010) [E3]
Co-authorsBente Talseth-Palmer, Rodney Scott, Liz Holliday, John Attia
2009Evans T-J, Bowden NA, Talseth-Palmer B, Catchpoole D, Scott R, 'Copy number variation in childhood acute lmphoblastic leukaemia', AMATA 2009, Katoomba, NSW (2009) [E3]
Co-authorsBente Talseth-Palmer, Nikola Bowden, Rodney Scott
2008Talseth-Palmer B, McPhillips M, Meldrum C, Groombridge C, Spigelman A, Scott R, 'Hereditary nonpolyposis colorectal cancer in families: Mutations, age of diagnosis of cancer and cancer incidence', Conference on Translational Cancer Research: Abstracts, Newcastle, NSW (2008) [E3]
Co-authorsBente Talseth-Palmer, Rodney Scott
2005Ashton KA, Talseth-Palmer B, Meldrum CJ, McPhillips ML, Scott R, 'COMT polymorphism (V158M) and its association with endometrial cancer in HNPCC families that adhere to the Amsterdam or Bethesda criteria', Human Genetics Society of Australasia 29th Annual Conference, Newcastle, NSW (2005) [E3]
Co-authorsKatie Ashton, Bente Talseth-Palmer, Rodney Scott
2005Talseth-Palmer B, Meldrum C, Ashton KA, Scott R, 'Age of disease onset in HNPCC patients is more complex than that predicted by R72P polymorphism in TP53', Human Genetics Society of Australasia 29th Annual Conference, Newcastle, NSW (2005) [E3]
Co-authorsBente Talseth-Palmer, Rodney Scott, Katie Ashton
2003Naluai AT, Adamovic S, Louka AS, Nilsson S, Talseth B, Gudjonsdottir AH, et al., 'Celiac disease is associated to a haplotype on 5q in Scandinavian families.', AMERICAN JOURNAL OF HUMAN GENETICS, LOS ANGELES, CALIFORNIA (2003)
Author URL
Co-authorsBente Talseth-Palmer
Show 18 more conferences
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Grants and Funding

Summary

Number of grants10
Total funding$1,198,573

Click on a grant title below to expand the full details for that specific grant.


20132 grants / $661,541

Identification of genetic factors of inherited colon cancer$454,798

Funding body: Cancer Institute NSW

Funding bodyCancer Institute NSW
Project TeamDoctor Bente Talseth-Palmer
SchemeEarly Career Fellowship
RoleLead
Funding Start2013
Funding Finish2013
GNoG1200857
Type Of FundingOther Public Sector - State
Category2OPS
UONY

Uncovering the link between obesity and cancer using random forests in an elastic cloud$206,743

Funding body: Cancer Institute NSW

Funding bodyCancer Institute NSW
Project TeamProfessor Rodney Scott, Doctor Bente Talseth-Palmer
SchemeNSW Premier's Awards for Outstanding Cancer Research: "Big Data, Big Impact" Grant
RoleInvestigator
Funding Start2013
Funding Finish2014
GNoG1300824
Type Of FundingOther Public Sector - State
Category2OPS
UONY

20121 grants / $10,000

Revealing cancer complexity - identification of Lynch syndrome cases$10,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamDoctor Bente Talseth-Palmer, Professor Rodney Scott, Doctor Liz Holliday
SchemeEarly Career Researcher Grant
RoleLead
Funding Start2012
Funding Finish2012
GNoG1200519
Type Of FundingInternal
CategoryINTE
UONY

20111 grants / $290,032

Genetics of HNPCC$290,032

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamDoctor Bente Talseth-Palmer
SchemeTraining (Postdoctoral) Fellowships - Peter Doherty Biomedical Fellowship (Australia)
RoleLead
Funding Start2011
Funding Finish2011
GNoG1000522
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

20101 grants / $2,000

The 21st Meeting of the European Association for Cancer Research, Norges Varemesse (Norway Trade Fairs), 26 - 29 June 2010$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding bodyUniversity of Newcastle - Faculty of Health and Medicine
Project TeamDoctor Bente Talseth-Palmer
SchemeTravel Grant
RoleLead
Funding Start2010
Funding Finish2010
GNoG1000515
Type Of FundingInternal
CategoryINTE
UONY

20093 grants / $204,000

Genome wide SNP associated study of childhood acute lymphoblastic leukaemia$140,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamProfessor Rodney Scott, Doctor Nikola Bowden, Doctor Bente Talseth-Palmer
SchemePaediatric Oncology Project Grant
RoleInvestigator
Funding Start2009
Funding Finish2009
GNoG0189790
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Search for modifier genes influencing breast cancer incidence in families diagnosed with hereditary nonpolyposis colorectal cancer$60,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamDoctor Bente Talseth-Palmer, Professor Rodney Scott
SchemeBreast Cancer Project Grant
RoleLead
Funding Start2009
Funding Finish2009
GNoG0189856
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

PULSE Education Prize$4,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamDoctor Bente Talseth-Palmer
SchemePULSE Education Prize
RoleLead
Funding Start2009
Funding Finish2009
GNoG0189891
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

20081 grants / $20,000

Genome wide SNP association study of childhood acute lymphoblastic leukaemia$20,000

Funding body: Hunter Children`s Research Foundation

Funding bodyHunter Children`s Research Foundation
Project TeamDoctor Nikola Bowden, Professor Rodney Scott, Doctor Bente Talseth-Palmer
SchemePaediatric Oncology Project Grant
RoleInvestigator
Funding Start2008
Funding Finish2008
GNoG0188483
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

20061 grants / $11,000

Genetic origins of childhood cancer$11,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamProfessor Rodney Scott, Doctor Bente Talseth-Palmer
SchemeProject Grant
RoleInvestigator
Funding Start2006
Funding Finish2006
GNoG0186093
Type Of FundingContract - Aust Non Government
Category3AFC
UONY
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Research Supervision

Current Supervision

CommencedResearch Title / Program / Supervisor Type
2011Copy Number Variants and Their Role in Hereditary Breast and Colorectal Cancers
Health, Faculty of Health and Medicine
Co-Supervisor
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Dr Bente Talseth-Palmer

Position

Cancer Institute ECR Fellow
Medical Genetics/Centre for Information-Based Medicine
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine

Focus area

Medical Genetics

Contact Details

Emailbente.talseth-palmer@newcastle.edu.au
Phone(02) 4042 0328

Office

RoomRoom 3105, Level 3 West, HMRI
BuildingHMRI
LocationRankin Park

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