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Dr Bente Talseth-Palmer

Cancer Institute ECR Fellow

School of Biomedical Sciences and Pharmacy (Medical Genetics)

Career Summary

Biography

Dr Talseth-Palmer was awarded her PhD in January 2008, which was undertaken in the HMRI's NBN Telethon Childhood Cancer research laboratory. She was awarded the research higher degree award for excellence in the Faculty of Health in recognition of outstanding research achievement for her Doctor of Philosophy research thesis. In January 2008, she successfully obtained a Gladys M. Brawn Memorial Post-Doctoral fellowship from the University of Newcastle and is now a part of the HMRI's, Information-Based Medicine Research Program. Prior to completing her PhD, Dr Talseth-Palmer completed a Bachelor of Medical Laboratory Technology in Norway in 1999 and a Masters of Genetic Counselling at the University of Newcastle in 2004. Between 1999 and 2003, Dr Talseth-Palmer worked as a research assistant focusing on genetic research both in Iceland and Norway. In 2006, Dr Talseth-Palmer was awarded a travel grant to attend the 11th International Congress of Human Genetics by the Human Genetics Society of Australasia (HGSA). In 2008, she was nominated as 10 of the best research showcases at the University of Newcastle and, in 2009, she was awarded the Hunter Medical Research Institute (HMRI) Pulse Education Prize, an award presented to outstanding early career researchers. Dr Talseth-Palmer is also an invited reviewer for the journal, Cancer Causes & Control.

Research Expertise
- Single Nucleotide Polymorphisms (SNPs) - Modifier genes - Genetic variation - Hereditary Non-Polyposis Colorectal Cancer (HNPCC) - Acute Lymphoblastic Leukaemia (ALL) - Genome-wideSNP array technology

Collaborations
Dr Talseth-Palmer is currently collaborating in several international studies: HNPCC, Juul Wijnen, LUMC, the Netherlands; MOMA study, Malcolm Dunlop, MRC, UK; 6-SNP collaboration, Annika Lindblom, Karolinska Institute, Sweden; and Modifier genes in HNPCC, Jan Lubinski, International Hereditary Cancer Center, Poland.


Qualifications

  • Doctor of Philosophy, University of Newcastle
  • Master of Genetic Counselling, University of Newcastle

Keywords

  • Acute Lymphoblastic Leukaemia (ALL)
  • Genetic variation
  • Genome-wideSNP array technology
  • Hereditary Non-Polyposis Colorectal Cancer (HNPCC)
  • Honours supervision
  • Modifier genes
  • Single Nucleotide Polymorphisms (SNPs)

Languages

  • English (Fluent)
  • Norwegian (Fluent)

Fields of Research

Code Description Percentage
060499 Genetics not elsewhere classified 50
111799 Public Health and Health Services not elsewhere classified 10
111299 Oncology and Carcinogenesis not elsewhere classified 40

Professional Experience

UON Appointment

Title Organisation / Department
Cancer Institute ECR Fellow University of Newcastle
School of Biomedical Sciences and Pharmacy
Australia

Academic appointment

Dates Title Organisation / Department
1/01/2011 - 1/12/2014 NHMRC Training (Post-Doctoral) Fellow

NHMRC - Australia Fellowship (Formerly Australia Fellowship Scheme)

University of Newcastle
Australia
1/01/2009 -  Membership - The Australasian Microarray & Associated Technologies Association (AMATA) The Australasian Microarray & Associated Technologies Association (AMATA)
Australia
1/01/2008 - 1/12/2010 Glady's M. Brawn Memorial Post-Doctoral Fellow University of Newcastle
Australia
1/01/2008 -  Membership - Hunter Children's Research Executive (HCRE) Subcommittee Hunter Childrens Research Executive (HCRE) Subcommittee
Australia
1/01/2008 -  Brawn Post Doc Fellow University of Newcastle
Australia
1/01/2007 - 31/12/2008 Membership - Business & Professional Woman (BPW) Australia Business & Professional Woman (BPW) Australia
Australia
1/01/2007 -  Membership - Australian Society for Medical Research (ASMR) The Australian Society for Medical Research
1/01/2003 -  Membership - Human Genetics Society of Australasia (HGSA) Human Genetics Society of Australasia (HGSA)
Australia
1/05/2000 - 1/12/2002 Research Assistant University of Oslo
Norway
1/07/1999 - 1/05/2000 Research Assistant Iceland Genomic Corporation
Iceland

Professional appointment

Dates Title Organisation / Department
1/06/2004 - 1/09/2004 Genetic Counsellor Hunter New England Health
Australia

Awards

Recipient

Year Award
2008 Higher degree excellence
University of Newcastle
2004 NBN Telethon Childhood Cancer PhD Scholarship
University of Newcastle

Research Award

Year Award
2009 Hunter Medical Research Institute (HMRI) Pulse Education Prize
Unknown
2008 Poster prize
Unknown
2006 Travel grant
Human Genetics Society of Australasia (HGSA)
2005 Cancer Institute NSW Research Scholar Award
Cancer Institute NSW
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (1 outputs)

Year Citation Altmetrics Link
2012 Scott R, Reeves SG, Talseth-Palmer B, 'The role of modifier genes in Lynch Syndrome', Colorectal Cancer Biology From Genes To Tumor, InTech, Slovenia 37-58 (2012) [B1]
DOI 10.5772/1163
Co-authors Bente Talseth-Palmer, Rodney Scott

Journal article (29 outputs)

Year Citation Altmetrics Link
2014 Evans TJ, Milne E, Anderson D, de Klerk NH, Jamieson SE, Talseth-Palmer BA, et al., 'Confirmation of childhood acute lymphoblastic leukemia variants, ARID5B and IKZF1, and interaction with parental environmental exposures.', PLoS One, 9 e110255 (2014) [C1]
DOI 10.1371/journal.pone.0110255
Citations Scopus - 1Web of Science - 1
Co-authors Liz Holliday, Bente Talseth-Palmer, Rodney Scott, John Attia, Nikola Bowden
2014 Masson AL, Talseth-Palmer BA, Evans T-J, Grice DM, Hannan GN, Scott RJ, 'Expanding the genetic basis of copy number variation in familial breast cancer', Hereditary Cancer in Clinical Practice, 12 (2014) [C1]

Introduction: Familial breast cancer (fBC) is generally associated with an early age of diagnosis and a higher frequency of disease among family members. Over the past two decades... [more]

Introduction: Familial breast cancer (fBC) is generally associated with an early age of diagnosis and a higher frequency of disease among family members. Over the past two decades a number of genes have been identified that are unequivocally associated with breast cancer (BC) risk but there remain a significant proportion of families that cannot be accounted for by these genes. Copy number variants (CNVs) are a form of genetic variation yet to be fully explored for their contribution to fBC. CNVs exert their effects by either being associated with whole or partial gene deletions or duplications and by interrupting epigenetic patterning thereby contributing to disease development. CNV analysis can also be used to identify new genes and loci which may be associated with disease risk.Methods: The Affymetrix Cytogenetic Whole Genome 2.7 M (Cyto2.7 M) arrays were used to detect regions of genomic re-arrangement in a cohort of 129 fBC BRCA1/BRCA2 mutation negative patients with a young age of diagnosis (<50 years) compared to 40 unaffected healthy controls (>55 years of age).Results: CNV analysis revealed the presence of 275 unique rearrangements that were not present in the control population suggestive of their involvement in BC risk. Several CNVs were found that have been previously reported as BC susceptibility genes. This included CNVs in RPA3, NBN (NBS1), MRE11A and CYP19A1 in five unrelated fBC patients suggesting that these genes are involved in BC initiation and/or progression. Of special interest was the identification of WWOX and FHIT rearrangements in three unrelated fBC patients.Conclusions: This study has identified a number of CNVs that potentially contribute to BC initiation and/or progression. The identification of CNVs that are associated with known tumour suppressor genes is of special interest that warrants further larger studies to understand their precise role in fBC. © 2014 Masson et al.; licensee BioMed Central Ltd.

DOI 10.1186/1897-4287-12-15
Co-authors Bente Talseth-Palmer, Rodney Scott
2013 Masson AL, Talseth-Palmer BA, Evans T-J, Grice DM, Duesing K, Hannan GN, Scott RJ, 'Copy number variation in hereditary non-polyposis colorectal cancer', Genes, 4 536-555 (2013) [C1]
DOI 10.3390/genes4040536
Co-authors Rodney Scott, Bente Talseth-Palmer
2013 Talseth-Palmer BA, Wijnen JT, Barker D, Vasen HFA, Scott RJ, 'Is the reported modifying effect of 8q23.3 and 11q23.1 on colorectal cancer risk for MLH1 mutation carriers valid? Reply', INTERNATIONAL JOURNAL OF CANCER, 133 1764-1764 (2013) [C3]
DOI 10.1002/ijc.28178
Co-authors Bente Talseth-Palmer, Rodney Scott
2013 Talseth-Palmer B, Wijnen JT, Brenne IS, Jagmohan-Changur S, Barker DJ, Ashton KA, et al., 'Combined analysis of three Lynch syndrome cohorts confirms the modifying effects of 8q23.3 and 11q23.1 in MLH1 mutation carriers', International Journal of Cancer, 132 1487-1729 (2013) [C1]
Citations Scopus - 6Web of Science - 7
Co-authors Rodney Scott, Katie Ashton, Bente Talseth-Palmer
2013 Chen J, Pande M, Huang Y-J, Wei C, Amos CI, Talseth-Palmer BA, et al., 'Cell cycle-related genes as modifiers of age of onset of colorectal cancer in Lynch syndrome: a large-scale study in non-Hispanic white patients', CARCINOGENESIS, 34 299-306 (2013) [C1]
DOI 10.1093/carcin/bgs344
Citations Scopus - 3Web of Science - 3
Co-authors Bente Talseth-Palmer, Rodney Scott
2013 Talseth-Palmer BA, Wijnen JT, Grice DM, Scott RJ, 'Genetic modifiers of cancer risk in Lynch syndrome: a review', FAMILIAL CANCER, 12 207-216 (2013) [C1]
DOI 10.1007/s10689-013-9614-2
Citations Scopus - 3Web of Science - 2
Co-authors Rodney Scott, Bente Talseth-Palmer
2013 Talseth-Palmer BA, Wijnen JT, Andreassen EK, Barker D, Jagmohan-Changur S, Tops CM, et al., 'The importance of a large sample cohort for studies on modifier genes influencing disease severity in FAP patients.', Hered Cancer Clin Pract, 11 20 (2013) [C1]
DOI 10.1186/1897-4287-11-20
Citations Scopus - 2Web of Science - 1
Co-authors Bente Talseth-Palmer, Rodney Scott
2013 Talseth-Palmer B, Holliday EG, Evans T-J, McEvoy MA, Attia JR, Grice DM, et al., 'Continuing difficulties in interpreting CNV data: Lessons from a genome-wide CNV association study of Australian HNPCC/lynch syndrome patients', BMC Medical Genomics, 6 1-13 (2013) [C1]
Citations Scopus - 3Web of Science - 3
Co-authors John Attia, Liz Holliday, Bente Talseth-Palmer, Rodney Scott
2013 Picelli S, Lorenzo Bermejo J, Chang-Claude J, Hoffmeister M, Fernandez-Rozadilla C, Carracedo A, et al., 'Meta-Analysis of Mismatch Repair Polymorphisms within the Cogent Consortium for Colorectal Cancer Susceptibility', PLOS ONE, 8 (2013) [C1]
DOI 10.1371/journal.pone.0072091
Citations Scopus - 3Web of Science - 3
Co-authors Rodney Scott, Bente Talseth-Palmer
2012 Talseth-Palmer B, Scott R, Vasen HFA, Wijnen JT, '8q23.3 and 11q23.1 as modifying loci influencing the risk for CRC in Lynch syndrome', European Journal of Human Genetics, 20 487-488 (2012) [C3]
Citations Scopus - 2Web of Science - 2
Co-authors Bente Talseth-Palmer, Rodney Scott
2011 Kiejda KA, Bowden NA, Croft AJ, Scurr LL, Kairupan CF, Ashton KA, et al., 'P53 in human melanoma fails to regulate target genes associated with apoptosis and the cell cycle and may contribute to proliferation', BMC Cancer, 11 203-219 (2011) [C1]
DOI 10.1186/1471-2407-11-203
Citations Scopus - 28Web of Science - 21
Co-authors Katie Ashton, Bente Talseth-Palmer, Kelly Kiejda, Rodney Scott, Nikola Bowden, Xu Zhang
2011 Talseth-Palmer B, Scott R, 'Genetic variation and its role in malignancy', International Journal of Biomedical Science, 7 158-171 (2011) [C1]
Citations Scopus - 1
Co-authors Rodney Scott, Bente Talseth-Palmer
2011 Talseth-Palmer B, Brenne IS, Ashton KA, Evans T-J, McPhillips M, Groombridge C, et al., 'Colorectal cancer susceptibility loci on chromosome 8q23.3 and 11q23.1 as modifiers for disease expression in lynch syndrome', Journal of Medical Genetics, 48 279-284 (2011) [C1]
DOI 10.1136/jmg.2010.079962
Citations Scopus - 25Web of Science - 20
Co-authors Rodney Scott, Katie Ashton, Bente Talseth-Palmer
2011 Wong-Brown M, Nordfors C, Mossman D, Pecenpetelovska G, Kiejda KA, Talseth-Palmer B, et al., 'BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer', Breast Cancer Research and Treatment, 127 853-859 (2011) [C1]
DOI 10.1007/s10549-011-1443-0
Citations Scopus - 39Web of Science - 37
Co-authors Rodney Scott, Kelly Kiejda, Michelle Wong-Brown, Bente Talseth-Palmer, Nikola Bowden
2010 Talseth-Palmer B, McPhillips M, Groombridge C, Spigelman A, Scott R, 'MSH6 and PMS2 mutation positive Australian Lynch syndrome families: Novel mutations, cancer risk and age of diagnosis of colorectal cancer', Hereditary Cancer in Clinical Practice, 8 1-10 (2010) [C1]
DOI 10.1186/1897-4287-8-5
Citations Scopus - 10Web of Science - 9
Co-authors Bente Talseth-Palmer, Rodney Scott
2009 Shi Z, Johnstone DM, Talseth-Palmer B, Evans T-J, Spigelman AD, Groombridge C, et al., 'Haemochromatosis HFE gene polymorphisms as potential modifiers of hereditary nonpolyposis colorectal cancer risk and onset age', International Journal of Cancer, 125 78-83 (2009) [C1]
DOI 10.1002/ijc.24304
Co-authors Rodney Scott, Liz Milward, Bente Talseth-Palmer
2009 Talseth-Palmer B, Bowden NA, Meldrum C, Nicholl J, Thompson E, Friend K, et al., 'A 1q44 deletion, paternal UPD of chromosome 2 and a deletion due to a complex translocation detected in children with abnormal phenotypes using new SNP array technology', Cytogenetic and Genome Research, 124 94-101 (2009) [C1]
DOI 10.1159/000200093
Citations Scopus - 4Web of Science - 4
Co-authors Nikola Bowden, Rodney Scott, Bente Talseth-Palmer
2008 Talseth-Palmer B, Bowden NA, Hill A, Meldrum C, Scott R, 'Whole genome amplification and its impact on CGH array profiles', BMC Research Notes, 1 108 (2008) [C1]
DOI 10.1186/1756-0500-1-56
Citations Scopus - 12
Co-authors Nikola Bowden, Bente Talseth-Palmer, Rodney Scott
2008 Talseth-Palmer B, Ashton KA, Meldrum C, Suchy J, Kurzawski G, Lubinski J, Scott R, 'Aurora-A and Cyclin D1 polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer', International Journal of Cancer, 122 1273-1277 (2008) [C1]
DOI 10.1002/ijc.23177
Citations Scopus - 22Web of Science - 18
Co-authors Bente Talseth-Palmer, Katie Ashton, Rodney Scott
2007 Talseth-Palmer B, Meldrum C, Suchy J, Kurzawski G, Lubinski J, Scott R, 'MDM2 SNP309 T > G alone or in combination with the TP53 R72P polymorphism does not appear to influence disease expression and age of diagnosis of colorectal cancer in HNPCC patients', International Journal of Cancer, 120 563-565 (2007) [C1]
DOI 10.1002/ijc.22339
Citations Scopus - 27Web of Science - 28
Co-authors Rodney Scott, Bente Talseth-Palmer
2007 Talseth-Palmer B, Meldrum C, Suchy J, Kurzawski G, Lubinski J, Scott R, 'Lack of association between genetic polymorphisms in cytokine genes and disease expression in patients with hereditary non-polyposis colorectal cancer', Scandinavian Journal of Gastroenterology, 42 628-632 (2007) [C1]
DOI 10.1080/00365520601106699
Citations Scopus - 10Web of Science - 9
Co-authors Bente Talseth-Palmer, Rodney Scott
2006 Talseth-Palmer B, Meldrum C, Suchy J, Kurzawski G, Lubinski J, Scott R, 'Age of diagnosis of colorectal cancer in HNPCC patients is more complex than that predicted by R72P polymorphism in TP53', International Journal of Cancer, 118 2479-2484 (2006) [C1]
DOI 10.1002/ijc.21661
Citations Scopus - 25Web of Science - 22
Co-authors Bente Talseth-Palmer, Rodney Scott
2006 Talseth-Palmer B, Meldrum C, Suchy J, Kurzawski G, Lubinski J, Scott R, 'Genetic polymorphisms in xenobiotic clearance genes and their influence on disease expression in hereditary nonpolyposis colorectal cancer patients', Cancer Epidemiology Biomarkers & Prevention, 15 2307-2310 (2006) [C1]
DOI 10.1158/1055-9965.EPI-06-0040
Citations Scopus - 16Web of Science - 13
Co-authors Bente Talseth-Palmer, Rodney Scott
2003 Louka AS, Lie BA, Talseth B, Ascher H, Ek J, Gudjonsdottir AH, Sollid LM, 'Coeliac disease patients carry conserved HLA-DR3-DQ2 haplotypes revealed by association of TNF alleles', Immunogenetics, 55 339-343 (2003) [C1]
DOI 10.1007/s00251-003-0586-5
Citations Scopus - 24Web of Science - 24
Co-authors Bente Talseth-Palmer
2003 Louka AS, Moodie SJ, Karell K, Bolognesi E, Ascher H, Greco L, et al., 'A collaborative European search for non-DQA1 *05-DQB1 *02 Celiac disease loci on HLA-Dr3 haplotypes: Analysis of transmission from homozygous parents', Human Immunology, 64 350-358 (2003)

The HLA-DQA1 *05 with DQB1 *02 alleles are a major risk factor for celiac disease (CD). To search for additional human leukocyte antigen (HLA) risk factors, we looked on the DR3-D... [more]

The HLA-DQA1 *05 with DQB1 *02 alleles are a major risk factor for celiac disease (CD). To search for additional human leukocyte antigen (HLA) risk factors, we looked on the DR3-DQ2 risk haplotype, selected because it carries both DQ risk alleles in cis and is the more represented among CD patients. In a European consortium, we identified 109 families with a parent homozygous for DQA1 *05-DQB1 *02. We typed ten microsatellites in the extended HLA complex, and applied the homozygous-parent transmission disequilibrium test (HPTDT) and extended-TDT to transmissions from homozygous parents. These methods eliminate confounding due to linkage disequilibrium between candidate disease loci and the known risk factor DQA1 *05-DQB1 *02, and are favorable when sufficient families are available. We did not find evidence of association with any single market or allele, although weak evidence for additional risk was observed, represented by preferential transmission of six adjacent markers. We tested the largest ever reported HPTDT population in CD, providing unprecedented power. We did not find significant evidence of additional risk-modifying factors on the DR3 haplotype, independent of DQA1 *05-DQB1 *02, although a weak tendency was observed for the B8-DR3 haplotype. This effect should be tested in large populations with significant representations of both B8-DR3 and non-B8 DR3 haplotypes. © American Society for Histocompatibility and Immunogenetics, 2003. Published by Elsevier Science Inc.

DOI 10.1016/S0198-8859(02)00822-4
Citations Scopus - 20
Co-authors Bente Talseth-Palmer
2003 Babron M-C, Nilsson S, Adamovic S, Naluai ÅT, Wahlström J, Ascher H, et al., 'Meta and pooled analysis of European coeliac disease data', European Journal of Human Genetics, 11 828-834 (2003)

Four full genome scans have been carried out by the partners of the European cluster on coeliac disease as well as follow-up studies of candidate regions. No region outside HLA sh... [more]

Four full genome scans have been carried out by the partners of the European cluster on coeliac disease as well as follow-up studies of candidate regions. No region outside HLA showed significant linkage to the disease in any single study. We first applied a meta-analysis based on a modification of Genome Screen Meta-Analysis to take into account the different linkage statistics, the arbitrariness of bin cutoff points, as well as the sample size of each study. We then performed a pooled linkage analysis of all families and raw genotypes. Besides the HLA region, already known to harbour a risk factor for coeliac disease, both approaches leave very little doubt on the presence of a genetic risk factor in the 5q31-33 region. This region was suggested by several individual studies, but did not reach statistical values high enough to be conclusive when data sets were analysed separately.

DOI 10.1038/sj.ejhg.5201051
Citations Scopus - 70
Co-authors Bente Talseth-Palmer
2002 Louka A, Nilsson S, Olsson M, Talseth B, Lie B, Ek J, et al., 'HLA in coeliac disease families: a novel test of risk modification by the 'other' haplotype when at least one DQA1*05-DQB1*02 haplotype is carried. (2002) [C1]
Citations Scopus - 35Web of Science - 34
Co-authors Bente Talseth-Palmer
2001 Kristinsson S, Thorolfsdottir E, Talseth B, Steingrimsson E, Thorsson A, Helgason T, et al., 'MODY in Iceland is associated with mutations in HNF-1alpha and a novel mutation in NeuroD1. (2001) [C1]
Citations Scopus - 56Web of Science - 48
Co-authors Bente Talseth-Palmer
Show 26 more journal articles

Conference (21 outputs)

Year Citation Altmetrics Link
2014 Talseth-Palmer BA, Evans TJ, Spigelman A, Scott RJ, 'Targeted next-generation sequencing - Identification of Lynch syndrome cases', EUROPEAN JOURNAL OF CANCER (2014) [E3]
Co-authors Rodney Scott, Bente Talseth-Palmer
2013 Talseth-Palmer B, Meldrum C, Ashton KA, Spigelman A, Scott RJ, 'Revealing cancer complexity - Identification of Lynch syndrome cases', Familial Cancer, Carins, QLD (2013) [E3]
Co-authors Bente Talseth-Palmer, Katie Ashton, Rodney Scott
2013 Talseth-Palmer B, Wijnen JT, Andreassen EK, Jagmohan-Changur S, Barker D, Tops CM, et al., 'The importance of a large sample cohort for studies on modifier genes influencing disease development in FAP patients', Familial Cancer, Carins, QLD (2013) [E3]
Co-authors Rodney Scott, Bente Talseth-Palmer
2012 Talseth-Palmer B, Scott R, 'A step closer to personalised medicine for Lynch Syndrome patients - Personalised screening can prevent cancer development in MLH1 mutation carriers', BDC 2012. 2nd Biomarker Discovery Conference, Shoal Bay, NSW (2012) [E3]
Co-authors Bente Talseth-Palmer, Rodney Scott
2012 Talseth-Palmer B, Wijen J, Brenne I, Jagomohan-Changur S, Baker D, Ashton KA, et al., 'Colorectal cancer risk modification in Lynch syndrome', Human Genome Meeting 2012: Genetics and Genomics in Personalised Medicine. Abstract Book, Sydney, NSW (2012) [E3]
Co-authors Katie Ashton, Bente Talseth-Palmer, Rodney Scott
2012 Talseth-Palmer B, Holliday EG, Evans T-J, McEvoy MA, Attia JR, Grice DM, et al., 'A genome-wide CNV association study of Australian HNPCC/Lynch syndrome patients', Proceedings of the Australian Health & Medical Research Congress 2012, Adelaide, SA (2012) [E3]
Co-authors John Attia, Liz Holliday, Rodney Scott, Bente Talseth-Palmer
2011 Talseth-Palmer B, Wijnen JT, Brenne IS, Jagmohan-Changur S, Ashton KA, Tops CM, et al., 'Chromosome 8q23.3, 10p14 and 11q23.1 variants modify colorectal cancer risk in Lynch syndrome - a combined analysis of the Australian, Dutch and Polish Lynch syndrome cohorts', Familial Aspects of Cancer: Research and Practice 2011, Kingscliff, NSW (2011) [E3]
Co-authors Rodney Scott, Katie Ashton, Bente Talseth-Palmer
2011 Talseth-Palmer B, Wijnen JT, Brenne IS, Jagmohan-Changur S, Ashton KA, Tops CM, et al., 'Chromosome 8q23.3 AND 11q23.1 variants modify colorectal cancer risk in Lynch syndrome: A meta-analysis of the Dutch and Australian Lynch syndrome cohorts', Abstracts: 4th Biennial Meeting: International Society for Gastrointestinal Hereditary Tumours, San Antonio, TX (2011) [E3]
Co-authors Rodney Scott, Bente Talseth-Palmer, Katie Ashton
2011 Martin AL, Talseth-Palmer B, Grice DM, Hannan G, Scott R, 'Elucidating the genetic predisposition to colorectal cancer', XIX NSW Scientific Meeting. Programme, Sydney, NSW (2011) [E3]
Co-authors Bente Talseth-Palmer, Rodney Scott
2010 Talseth-Palmer B, Holliday EG, Evans T-J, McPhillips M, Groombridge C, Spigelman AD, Scott R, 'Modifier genes influencing breast cancer incidence in HNPCC/Lynch syndrome', AMATA 2010 Conference: Conference Handbook, Hobart, Tasmania (2010) [E3]
Co-authors Liz Holliday, Rodney Scott, Bente Talseth-Palmer
2010 Scott R, Talseth-Palmer B, Reeves SG, Meldrum, Groombridge C, Spigelman AD, et al., 'MTHFR 677 C>T and 1298 A>C polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer', Familial Cancer, Dusseldorf, Germany (2010) [E3]
DOI 10.1038/ejhg.2008.239
Citations Scopus - 11Web of Science - 12
Co-authors Bente Talseth-Palmer, Rodney Scott
2010 Talseth-Palmer B, McPhillips M, Meldrum C, Groombridge C, Spigelman AD, Scott R, 'Hereditary nonpolyposis colorectal cancer in 688 families: Mutations, age of diagnosis and cancer incidence', Familial Cancer, Dusseldorf, Germany (2010) [E3]
Co-authors Rodney Scott, Bente Talseth-Palmer
2010 Talseth-Palmer B, McPhillips M, Meldrum C, Groombridge C, Spigelman AD, Scott R, 'Haemochromatosis HFE gene polymorphisms as ptential modifiers of hereditary nonpolyposis colorectal cancer risk and onset age', Familial Cancer, Dusseldorf, Germany (2010) [E3]
Citations Scopus - 17Web of Science - 13
Co-authors Bente Talseth-Palmer, Rodney Scott
2010 Evans T-J, Talseth-Palmer B, Brenne IS, Ashton KA, McPhillips M, Groombridge C, et al., 'Colorectal cancer suspectibility loci on chr 8q23.3 and 11q23.1 as modifiers for disease expression in Lynch syndrome', Sydney Cancer Conference 2010. Profiling Risk, Personalising Treatment and Predicting Outcomes. Conference Program and Abstract Book, Sydney, NSW (2010) [E3]
Co-authors Rodney Scott, Katie Ashton, Bente Talseth-Palmer
2010 Talseth-Palmer BA, Brenne IS, Ashton K, Evans TJ, McPhillips M, Groombridge C, et al., 'Colorectal cancer susceptibility loci on chr 8q23.3 and 11q23.1 as modifiers for disease expression in Lynch syndrome', EJC SUPPLEMENTS, Oslo, NORWAY (2010) [E3]
Co-authors Rodney Scott, Bente Talseth-Palmer
2010 Talseth-Palmer B, Holliday EG, Evans T-J, McPhillips M, McEvoy MA, Attia JR, Scott R, 'A modern approach to the search for modifying genetic loci infleuncing the high breast cancer incidence seen in an Australian HNPCC/Lynch Syndrome cohort', Proceedings of the Australian Health and Medical Research Congress 2010, Melbourne, Vic (2010) [E3]
Co-authors Bente Talseth-Palmer, Rodney Scott, Liz Holliday, John Attia
2009 Evans T-J, Bowden NA, Talseth-Palmer B, Catchpoole D, Scott R, 'Copy number variation in childhood acute lmphoblastic leukaemia', AMATA 2009, Katoomba, NSW (2009) [E3]
Co-authors Bente Talseth-Palmer, Nikola Bowden, Rodney Scott
2008 Talseth-Palmer B, McPhillips M, Meldrum C, Groombridge C, Spigelman A, Scott R, 'Hereditary nonpolyposis colorectal cancer in families: Mutations, age of diagnosis of cancer and cancer incidence', Conference on Translational Cancer Research: Abstracts, Newcastle, NSW (2008) [E3]
Co-authors Bente Talseth-Palmer, Rodney Scott
2005 Ashton KA, Talseth-Palmer B, Meldrum CJ, McPhillips ML, Scott R, 'COMT polymorphism (V158M) and its association with endometrial cancer in HNPCC families that adhere to the Amsterdam or Bethesda criteria', Human Genetics Society of Australasia 29th Annual Conference, Newcastle, NSW (2005) [E3]
Co-authors Katie Ashton, Bente Talseth-Palmer, Rodney Scott
2005 Talseth-Palmer B, Meldrum C, Ashton KA, Scott R, 'Age of disease onset in HNPCC patients is more complex than that predicted by R72P polymorphism in TP53', Human Genetics Society of Australasia 29th Annual Conference, Newcastle, NSW (2005) [E3]
Co-authors Bente Talseth-Palmer, Rodney Scott, Katie Ashton
2003 Naluai AT, Adamovic S, Louka AS, Nilsson S, Talseth B, Gudjonsdottir AH, et al., 'Celiac disease is associated to a haplotype on 5q in Scandinavian families.', AMERICAN JOURNAL OF HUMAN GENETICS, LOS ANGELES, CALIFORNIA (2003)
Co-authors Bente Talseth-Palmer
Show 18 more conferences
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Grants and Funding

Summary

Number of grants 10
Total funding $1,198,573

Click on a grant title below to expand the full details for that specific grant.


20132 grants / $661,541

Identification of genetic factors of inherited colon cancer$454,798

Funding body: Cancer Institute NSW

Funding body Cancer Institute NSW
Project Team Doctor Bente Talseth-Palmer
Scheme Early Career Fellowship
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1200857
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

Uncovering the link between obesity and cancer using random forests in an elastic cloud$206,743

Funding body: Cancer Institute NSW

Funding body Cancer Institute NSW
Project Team Professor Rodney Scott, Doctor Bente Talseth-Palmer
Scheme NSW Premier's Awards for Outstanding Cancer Research: "Big Data, Big Impact" Grant
Role Investigator
Funding Start 2013
Funding Finish 2014
GNo G1300824
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

20121 grants / $10,000

Revealing cancer complexity - identification of Lynch syndrome cases$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Bente Talseth-Palmer, Professor Rodney Scott, Doctor Liz Holliday
Scheme Early Career Researcher Grant
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1200519
Type Of Funding Internal
Category INTE
UON Y

20111 grants / $290,032

Genetics of HNPCC$290,032

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Bente Talseth-Palmer
Scheme Training (Postdoctoral) Fellowships - Peter Doherty Biomedical Fellowship (Australia)
Role Lead
Funding Start 2011
Funding Finish 2011
GNo G1000522
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

20101 grants / $2,000

The 21st Meeting of the European Association for Cancer Research, Norges Varemesse (Norway Trade Fairs), 26 - 29 June 2010$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Doctor Bente Talseth-Palmer
Scheme Travel Grant
Role Lead
Funding Start 2010
Funding Finish 2010
GNo G1000515
Type Of Funding Internal
Category INTE
UON Y

20093 grants / $204,000

Genome wide SNP associated study of childhood acute lymphoblastic leukaemia$140,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Rodney Scott, Doctor Nikola Bowden, Doctor Bente Talseth-Palmer
Scheme Paediatric Oncology Project Grant
Role Investigator
Funding Start 2009
Funding Finish 2009
GNo G0189790
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Search for modifier genes influencing breast cancer incidence in families diagnosed with hereditary nonpolyposis colorectal cancer$60,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Bente Talseth-Palmer, Professor Rodney Scott
Scheme Breast Cancer Project Grant
Role Lead
Funding Start 2009
Funding Finish 2009
GNo G0189856
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

PULSE Education Prize$4,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Bente Talseth-Palmer
Scheme PULSE Education Prize
Role Lead
Funding Start 2009
Funding Finish 2009
GNo G0189891
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20081 grants / $20,000

Genome wide SNP association study of childhood acute lymphoblastic leukaemia$20,000

Funding body: Hunter Children`s Research Foundation

Funding body Hunter Children`s Research Foundation
Project Team Doctor Nikola Bowden, Professor Rodney Scott, Doctor Bente Talseth-Palmer
Scheme Paediatric Oncology Project Grant
Role Investigator
Funding Start 2008
Funding Finish 2008
GNo G0188483
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20061 grants / $11,000

Genetic origins of childhood cancer$11,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Rodney Scott, Doctor Bente Talseth-Palmer
Scheme Project Grant
Role Investigator
Funding Start 2006
Funding Finish 2006
GNo G0186093
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y
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Research Supervision

Number of supervisions

Completed0
Current1

Total current UON EFTSL

PhD0.2

Current Supervision

Commenced Research Title / Program / Supervisor Type
2011 Copy Number Variants and Their Role in Hereditary Breast and Colorectal Cancers
Health, Faculty of Health and Medicine
Co-Supervisor
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Dr Bente Talseth-Palmer

Position

Cancer Institute ECR Fellow
Medical Genetics/Centre for Information-Based Medicine
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine

Focus area

Medical Genetics

Contact Details

Email bente.talseth-palmer@newcastle.edu.au
Phone (02) 4042 0328

Office

Room Room 3105, Level 3 West, HMRI
Building HMRI
Location Rankin Park

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