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Career Summary

Qualifications

  • PhD, University of Queensland, 22/05/1994
  • Bachelor of Science (Honours), University of Melbourne, 28/05/1987
  • Master of Science, University of Melbourne, 11/03/1992
  • Graduate Certificate Practice of Tertiary Teaching, University of Newcastle, 10/12/2007

Research

Research keywords

  • Autonomic Nervous System
  • Electrophysiology
  • Neuroanatomy
  • Pain and Sensory Dysfunction

Research expertise

My research centres on the structure and function of nerves which control our internal organs. This includes, the sensory neurons which give us information on the state of our internal organs, and the autonomic neurons which modify organ function. We are interested in how autonomic neurons receive information from other parts of the nervous system and how they process this information before sending signals to the final target organ. At present we are focusing on control of the female reproductive tract using a number of animal models. To study these complex nervous pathways we use a combination of electrical recording techniques, to monitor the activity of individual neurons, and anatomical techniques to visualise the shape and chemical content of neurons.

The major aim of our research is to build a picture of the types of neurons which are important in pelvic organ function and the nature of the chemical signals which neurons use to communicate with each other. This knowledge will be crucial to the design of therapies aimed at combating the wide range of diseases which involve perturbations of the autonomic and sensory nervous systems. Such maladies include incontinence, sexual dysfunction, and chronic pelvic pain.

Fields of Research

CodeDescriptionPercentage
110399Clinical Sciences Not Elsewhere Classified40
111600Medical Physiology40
060699Physiology Not Elsewhere Classified20

Memberships

Committee/Associations (relevant to research).

  • State Representitive (2002, 2003) - Australian Neuroscience Society

Awards

Research Award.

1996Australian Postdoctoral Fellowship
NHMRC (Australia)
One of very few recipients of these very competitive fellowships.

Teaching

Teaching keywords

  • Histology
  • Physiology
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Highlighted Publications

For publications that are currently unpublished or in-press, details are shown in italics.

YearCitationAltmetricsLink
2005Morris JL, Konig P, Shimizu T, Jobling P, Gibbins IL, 'Most peptide-containing sensory neurons lack proteins for exocytotic release and vesicular transport of glutamate', Journal of Comparative Neurology, 483 1-16 (2005) [C1]
2005Morris JL, Gibbins IL, Jobling P, 'Post-stimulus potentiation of transmission in pelvic ganglia enhances sympathetic dilatation of guinea-pig uterine artery in vitro', Journal of Physiology, 566 189-203 (2005) [C1]

Publications

For publications that are currently unpublished or in-press, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Chapter (1 outputs)

YearCitationAltmetricsLink
2012Jobling P, 'Visceral motoneurons', The Mouse Nervous System, Academic Press, San Diego 499-514 (2012) [B1]

Journal article (24 outputs)

YearCitationAltmetricsLink
2014Pundavela J, Demont Y, Jobling P, Lincz LF, Roselli S, Thorne RF, et al., 'ProNGF Correlates with Gleason Score and Is a Potential Driver of Nerve Infiltration in Prostate Cancer.', Am J Pathol, 184 3156-3162 (2014)
2014Jobling P, O'Hara K, Hua S, 'Female reproductive tract pain: targets, challenges, and outcomes.', Front Pharmacol, 5 17 (2014)
2014Gravina FS, van Helden DF, Kerr KP, de Oliveira RB, Jobling P, 'Phasic Contractions of the Mouse Vagina and Cervix at Different Phases of the Estrus Cycle and during Late Pregnancy.', PLoS One, 9 e111307 (2014)
2013Bobrovskaya L, Beard D, Bondarenko E, Beig MI, Jobling P, Walker FR, et al., 'Does exposure to chronic stress influence blood pressure in rats?', AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, 177 217-223 (2013) [C1]
2012Yeoh JW, James MH, Jobling P, Bains JS, Graham BA, Dayas CV, 'Cocaine potentiates excitatory drive in the perifornical/lateral hypothalamus', Journal of Physiology, 590 3677-3689 (2012) [C1]
2011Jobling P, 'Autonomic control of the urogenital tract', Autonomic Neuroscience: Basic and Clinical, 165 113-126 (2011) [C1]
2011Gravina FS, Jobling P, Kerr KP, De Oliveira R, Parkington HC, Van Helden DF, 'Oxytocin depolarizes mitochondria in isolated myometrial cells', Experimental Physiology, 96 949-956 (2011) [C1]
2010Gravina FS, Parkington HC, Kerr KP, De Oliveira R, Jobling P, Coleman HA, et al., 'Role of mitochondria in contraction and pacemaking in the mouse uterus', British Journal of Pharmacology, 161 1375-1390 (2010) [C1]
2010Jobling P, Graham BA, Brichta AM, Callister RJ, 'Cervix stimulation evokes predominantly subthreshold synaptic responses in mouse thoracolumbar and lumbosacral superficial dorsal horn neurons', Journal of Sexual Medicine, 7 2068-2076 (2010) [C1]
2009Jobling P, 'W-conotoxin GVIA sensitive calcium channels on preganglionic nerve terminals in mouse pelvic and celiac ganglia', Autonomic Neuroscience: Basic and Clinical, 146 56-61 (2009) [C1]
2008Jobling P, Lim R, 'Anatomical and physiological properties of pelvic ganglion neurons in female mice', Autonomic Neuroscience: Basic & Clinical, 140 30-39 (2008) [C1]
2005Morris JL, Konig P, Shimizu T, Jobling P, Gibbins IL, 'Most peptide-containing sensory neurons lack proteins for exocytotic release and vesicular transport of glutamate', Journal of Comparative Neurology, 483 1-16 (2005) [C1]
2005Morris JL, Gibbins IL, Jobling P, 'Post-stimulus potentiation of transmission in pelvic ganglia enhances sympathetic dilatation of guinea-pig uterine artery in vitro', Journal of Physiology, 566 189-203 (2005) [C1]
2004Jobling P, Gibbins IL, Lewis RJ, Morris JL, 'Differential expression of calcium channels in sympathetic and parasympathetic preganglionic inputs to neurons in paracervical ganglia of guinea-pigs.', Neuroscience, 127 455-466 (2004) [C1]
2004Ozols D, Morris JL, Lewis RJ, Gibbins IL, Jobling P, 'Differential involvement of N-type calcium channels in transmitter release from vasoconstrictor and vasodilator neurons.', British Journal of Pharmacology, 141 961-970 (2004) [C1]
2003Gibbins IL, Jobling P, Teo EH, Matthew SE, Morris JL, 'Heterogenous expression of SNAP-25 and synaptic vesicle proteins by central and peripheral inputs to sympathetic neurons.', Journal of Comparative Neurology, 459 25-43 (2003) [C1]
2003Jobling P, Gibbins IL, Morris JL, 'Functional organization of vasodilator neurons in pelvic ganglia of female guinea pigs: comparison with uterine motor neurons.', Journal of Comparative Neurology, 459 223-241 (2003) [C1]
2003Morris JL, Jobling P, Shimizu T, Gibbins IL, 'Interleukin-1 receptor immunoreactivity in sympathetic vascular and non vascular neurons in the guinea-pig coeliac ganglion', Neuroscience Letters, 333 54-58 (2003) [C1]
2003Anderson RL, Jobling P, Matthew SE, Gibbins IL, 'Development of convergent synaptic inputs to subpopulations of autonomic neurons', Journal of Comparative Neurology, 447 218-233 (2003) [C1]
2003Gibbins IL, Teo EH, Jobling P, Morris JL, 'Synaptic density, convergence and dendritic complexity of prevertebral sympathetic neurons. Journal of Comparative Neurology', Journal of Comparative Neurology, 455 285-298 (2003) [C1]
2002Morris JL, Jobling P, Gibbins IL, 'Botulinum neurotoxin A attenuates release of norepinepherine but not neuropeptide Y from vasoconstrictor neurons', American Journal of Physiology. 283: H2627-2635., 2627-2635 (2002) [C1]
2001Anderson RL, Jobling P, Gibbins IL, 'Development of electrophysiological and morphological diversity in autonomic neurons.', Journal of Neurophysiology 86: 1237-1251., 1237-1251 (2001) [C1]
2001Jobling P, Messenger JP, Gibbins IL, 'Differential expression of functionally identified and immunohistochemically identified NK1 receptors on sympathetic neurons.', Journal of Neurophysiology 85: 1888-1898., 1888-1898 (2001) [C1]
2001Morris JL, Jobling P, Gibbins IL, 'Differential inhibition by botulinum neurotoxin A of cotransmitters released from autonomic vasodilator neurons', American Journal of Physiology. 281: H2124-2132., 2124-2132 (2001) [C1]
Show 21 more

Review (1 outputs)

YearCitationAltmetricsLink
2003Gibbins IL, Jobling P, Morris JL, 'Functional organisation of peripheral vasomtor pathways', Acta Physilogica Scandinavica (2003) [D1]

Conference (14 outputs)

YearCitationAltmetricsLink
2012Jobling P, Madden JF, Graham BA, 'Whole cell patch clamp recordings from muscle spindle afferent neurons in intact dorsal root ganglia isolated from mouse', Abstracts. Australian Neuroscience Society 32nd Annual Meeting, Gold Coast, Queensland (2012) [E3]

Co-authors: BRETT GRAHAM

2011Jobling P, Smith K, Madden J, Hickey LR, Graham BA, 'Characterisation of pain behaviour, spinal neurochemistry and glial populations in a mouse antigen-induced arthritis model', Posters. Australian Neuroscience Society 31st Annual Meeting, Auckland, New Zealand (2011) [E3]

Co-authors: BRETT GRAHAM

2010Gravina FS, Van Helden DF, De Oliveira R, Kerr KP, Jobling P, 'Relaxant effects of methanandamide unmasked by indomethacin in the mouse uterus', Australasian Society of Clinical and Experimental Pharmacology and Toxicology (ASCEPT) Annual Scientific Meeting, Melbourne, 2010, Melbourne, Vic (2010) [E3]
2010Nalivaiko E, Beard D, Bondarenko E, Beig MI, Jobling P, Walker FR, et al., 'CHRONIC FOOTSHOCK STRESS CAUSES ENDURING CHANGES IN CIRCADIAN RHYTHMS, WITHOUT PROVOKING HYPERTENSION IN RATS', FASEB JOURNAL (2010) [E3]
2009Murali SS, Jobling P, 'Effects of neurokinin and cannabinoid receptor activation on the excitability of neurons in pelvic ganglia of female mice', ANS 2009 Abstracts: Posters, Canberra, ACT (2009) [E3]
2009Kerr KP, Jobling P, Gravina FS, Van Helden DF, 'Contractility of the lower uterus and upper vagina in the mouse', 43rd ASCEPT Annual Scientific Meeting: Proceedings, Sydney, NSW (2009) [E3]
2009Gravina FS, Jobling P, Kerr KP, De Oliveira R, Van Helden DF, 'Identification of cannabinoid receptor 1 and the effect of methanandamide on uterine contractions of the mouse uterus', 1st National Symposium on Advances in Urogenital and Gut Research, Melbourne, VIC (2009) [E3]
2008Anderson WB, Graham BA, Jobling P, Brichta AM, Callister RJ, 'Inhibitory synaptic transmission and cannabinoid effects differ in mouse superficial and deep dorsal horn neurons', Proceedings of the Australian Neuroscience Society, Hobart, TAS (2008) [E3]

Co-authors: ROBERT CALLISTER

2008Jobling P, Graham BA, Brichta AM, Callister RJ, 'In vivo patch clamp recording of synaptic events evoked in superficial dorsal horn neurons after stimulation of the female reproductive tract in the mouse', Proceedings of the Australian Neuroscience Society, Hobart, TAS (2008) [E3]
2006Jobling P, Graham BA, Brichta AM, Callister RJ, 'In vivo patch-clamp recording of subthreshold synaptic events evoked in dorsal horn neurons after stimulation of the female reproductive tract in the mouse', Society for Neuroscience, Atlanta, Georgia (2006) [E3]
2006Anderson WB, Graham BA, Jobling P, Lim R, Brichta AM, Callister RJ, 'Glycine receptor diversity in the dorsal horn of the mouse spinal cord', Society for Neuroscience, Atlanta, GA (2006) [E3]
2006Jobling P, 'Synaptic transmission and electrical properties of neurons in pelvic ganglia of female mice', Society for Neuroscience, Atlanta, GA (2006) [E3]
2005Morris JL, Grillett S, Vilimas P, Jobling P, Gibbins IL, 'Peptide release from sensory neurons in primary bronchus is resistant to blockade by botulinum neurotoxin A', FASEB JOURNAL, San Diego, CA (2005)
2005Morris JL, Gibbins IL, Jobling P, 'Sympathetic vasodilation of uterine arteries is amplified by non-cholinergic transmission in pelvic ganglia', FASEB JOURNAL, San Diego, CA (2005)
Show 11 more
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Grants and Funding

Summary

Number of grants13
Total funding$1,382,133

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2014 (2 grants)

Vascular adaptation of the newborn: Hydrogen sulphide as a fundamental signalling molecule and novel target for therapy$10,000
Funding Body: University of Newcastle

Project Team
Conjoint Professor Ian Wright, Doctor Phil Jobling, Professor Dirk Van Helden
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00020142014
GNo:G1301409

Neurobiological Investigation of Interstitial White Matter Neurons in a Maternal Infection Activation Model of Schizophrenia$2,608
Funding Body: Australian Rotary Health

Project Team
Associate Professor Paul Tooney, Doctor Phil Jobling, Doctor Brett Graham
SchemeRole
Ian Scott ScholarshipInvestigator
Total AmountFunding StartFunding Finish
$2,60820142016
GNo:G1301103

2013 (1 grants)

Leica TP 1020 Automatic Tissue Processor for histology applications$35,000
Funding Body: NHMRC (National Health & Medical Research Council)

2012 (1 grants)

Development of peripheral sensory pathways in humans$469,167
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Robert Callister, Associate Professor Alan Brichta, Dr David Hughes, Doctor Phil Jobling
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$469,16720122014
GNo:G1100102

2011 (1 grants)

How do the immune and nervous systems interact in arthritis?$20,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Phil Jobling, Doctor Brett Graham
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$20,00020112011
GNo:G1000987

2010 (1 grants)

ABI 7500 Real Time PCR System $34,000
Funding Body: NHMRC (National Health & Medical Research Council)

2009 (2 grants)

Neurometer CPT/C$28,435
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Philip Bolton, Professor Robert Callister, Associate Professor Alan Brichta, Professor Robin Callister, Doctor Brett Graham, Doctor Phil Jobling
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$28,43520092009
GNo:G0189845

Leica VT1200S - Fully automated vibrating blade microtome$16,209
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Robert Callister, Associate Professor Alan Brichta, Conjoint Professor Keith Jones, Associate Professor Jon Hirst, Doctor Brett Graham, Associate Professor Philip Bolton, Doctor Phil Jobling, Associate Professor Paul Tooney, Doctor Angela McPherson, Doctor Rebecca Lim, Doctor Ramatis De Oliveira, Mr Matthew Walsh
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$16,20920092009
GNo:G0189842

2008 (1 grants)

Recovery of the balance system following injury$24,069
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Alan Brichta, Professor Robert Callister, Associate Professor Philip Bolton, Doctor Phil Jobling, Doctor Rebecca Lim
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$24,06920082008
GNo:G0188471

2007 (1 grants)

3D Imaging Software/Work station$20,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor David Pow, Doctor Chris Dayas, Doctor Phil Jobling, Associate Professor Derek Laver
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020072007
GNo:G0188026

2006 (1 grants)

How does the nervous system process painful information from the uterus$16,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Phil Jobling
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$16,00020062006
GNo:G0186103

2004 (1 grants)

Studying the connections between nerve cells which control reproductive tissue$14,000
Funding Body: University of Newcastle

Project Team
Doctor Phil Jobling
SchemeRole
New Staff GrantChief Investigator
Total AmountFunding StartFunding Finish
$14,00020042004
GNo:G0185001

2000 (1 grants)

Neurotransmission in functionally distinct vasodilator pathways$692,645
Funding Body: National Health & Medical Research Council

SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$692,64520002004
GNo:18102235
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Research Supervision

Number of current supervisions5
Total current UoN PhD EFTSL1.25

For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20142018PhD(Experimental Pharmacology)Co-SupervisorNeurobiological Investigation of Interstitial White Matter Neurons in a Maternal Infection Activation Model of Schizophrenia
20142016PhD (Human Physiology)Principal SupervisorTumour Innervation and Trophic Factors
20132017PhD (Human Physiology)Co-SupervisorThe Role of Calretinin Positive Interneurons in Spinal Sensory Coding
20112015PhD (Human Physiology)Co-SupervisorThe Lymphatic Function in Diabetes
20082008Honours Pharmacology
University of Newcastle
Co-SupervisorModulation of neuronal excitability in neurons which control pelvic organs.

Past Supervision

YearProgramSupervisor TypeResearch Title
2011PhD (Human Physiology)Co-SupervisorContractile Properties of the Female Reproductive Tract
2006Honours Biol Sc Not Elsewhere Classifd
University of Newcastle
Co-SupervisorA study of the location and Characteristics of Neurons with Input from Deep Neck Structures
2003Honours Health Not Elswhere Classified
Flinders University
Co-SupervisorMechanisms of Neuropeptide Release from Sensory Neurons
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Dr Phillip (Phil) Jobling

Work Phone(02) 4921 5126
Fax(02) 4921 7406
Email
PositionSenior Lecturer
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine
The University of Newcastle, Australia
Focus AreaHuman Physiology
Office
MS406,
Medical Sciences,
Callaghan
University Drive
Callaghan NSW 2308
Australia
URL:www.newcastle.edu.au/profile/phillip-jobling