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Professor Marjorie Walker

Professor of Anatomical Pathology

School of Medicine and Public Health (Pathology)

Career Summary

Biography

Prof. Marjorie Walker currently holds the position of Professor of Anatomical Pathology in the School of Medicine and Public Health at the University of Newcastle. Prior to her appointment at Newcastle, Professor Walker held concurrent appointments as Reader and Honorary Consultant with the Histopathology Centre for Pathology at Imperial College London and Imperial College Healthcare NHS Trust Cellular Pathology Department, St Mary’s Hospital. She also served as Assistant Admissions Tutor at Imperial College. Her diagnostic specialty areas are GI pathology, Uropathology and Dermatopathology. Professor Walker has also previously held the position of Honorary Associate Professor in the Faculty of Medicine, University of Sydney, Australia (2008-11).

Research Expertise
My expertise as a histopathologist is in interpretation of clinical or molecular events in tissue sections, correlating both routine pathology and immunocytochemistry to demonstrate particular cells or their function or secretion with clinical patient data. I principally work in gastrointestinal and urological pathology, particularly prostate cancer. In the last 10 years I have developed expertise in upper gastrointestinal pathology and my current research is focused on finding biomarkers and pathways in functional bowel diseases, named functional as there is no discernible organic pathology.Over the next 5 years I plan to complete the investigation of functional bowel disorders and other gastrointestinal disorders to unravel the pathology which occurs in these diseases, and hope to elucidate the cause of these distressing conditions with the aim of devising effective agents for treatment. I am also working on coeliac disease and plan to continue defining parameters for diagnosis of coeliac disease in conjuction with the International Coeliac Definitions Group.

Teaching Expertise
My teaching experience extends across Undergraduate, Masters and Postgraduate levels. I have taught histopathology to undergraduate and graduate entry students at Imperial College in years 1 - 5, from basic principles to systems pathology. I contribute to course design, exam development and marking - as a senior examiner in pathology at Imperial College I have responsibility for setting and marking all years of undergraduates, and attend group marking sessions and examinations meetings. As Divisional Head of Teaching for Investigative Science (1999-2003), in the curriculum review at that time, I ensured that pathology was introduced as a standalone course, comprising lectures, tutorials and clinicopathological conferences to ensure that students see the integration of clinicians and the different pathology disciplines. I have lectured on principles of pathology to wide ranging groups, for example, perioperative surgical practitioners and ophthalmology FY2s. I also give invited lectures at National and International meetings.

Administrative Expertise
I have extensive administrative experience, having served on numerous committees and held the position of Assistant Admissions tutor at Imperial College. In this role, I was the sole clinician on the team and my duties included:

• Interviewer training

• Participation in Graduate Entry Open Days to promote the course at Imperial College.

• Yearly Admissions Discussion Forum

• Set and mark scholarship essays (50/year)

• Scrutinise prospectus for publication

• Chair undergraduate, graduate and direct entry interviews

• Shortlist candidates – group shortlisting sessions for graduates and undergraduates

I am also the UK representative for the European Society of Pathology Gastrointestinal Working Group (2005 – Present), which decides on topics of interest for short courses, symposia and slide seminars at the now yearly European Congress of Pathology. I have organised all types of sessions, which involves inviting histopathologists from Europe to participate. I undertake review of papers for Gut, American Journal of Gastroenterology, Alimentary Pharmacology and Therapeutics, Histopathology, Clinical Gastroenterology and Hepatology, Journal of Clinical Pathology, European Journal of Gastroenterology and Hepatology, Clin Chem Acta, European Journal of Surgical Oncology and the British Journal of Medical and Surgical Urology. I also review grants for CRUK and NHMRC (Australia) and am an Editorial Board member of Alimentary Pharmacology and Therapeutics.

Collaborations
My research collaborations include:

• Sweden (Professor Nick Talley, Professor Lars Agréus, Karolinska Institute) – Kalixanda and PopCol studies (epidemiology by endoscopy in the upper and lower GI tract) - Eosinophilic Oesophagitis, Coeliac Disease, Biomarkers in Functional Dyspepsia (FD) and Irritable Bowel Syndrome (IBS), Smoking and Allergies and Innate Immunity, Effect of Bile Reflux in the Stomach and Oesophagus, GI hormones in FD.

• Australia Nepean Duodenal Eosinophilia study - Pathology in Functional Dyspepsia (FD) in an Australian population (Professor Nick Talley Newcastle University, NSW, and Professor Martin Weltman Nepean Hospital University of Sydney)

• Chile/ Leeds UK - I am an expert advisor to the Content study – This is funded by the EU, a study on iron deficiency and infection in the gastrointestinal tract in children in Brazil, Chile and London (Professor Jean Crabtree, Leeds, UK, Dr Paul Harris, Santiago, Chile).

• Member, International Coeliac Definitions Group – an international group of physicians with a prime interest in coeliac disease, defining management and diagnosis of coeliac disease.

• Expert reviewer for oesophageal pathology in the Aspect (Aspirin Esomeprazole Chemoprevention) study in patients with Barrett's oesophagus (Chief Investigator: Professor Janusz Jankowski University Hospitals Leicester)

• XMRV in prostate cancer (Professor Myra McClure, Imperial College )

• Gene Dysregulation Prostate Cancer (Hammersmith Campus, Prostate Cancer Group (Dr Charlotte Bevan, Dr Robert Kypta, Dr Justin Sturge and Professor Jonathan Waxman) As the histopathologist to this group I interpret clinical data and immunostaining of tissue microarrays in unravelling prostate cancer pathways (Hey1, Hey L, FUS, WNT signalling, DKK3), in androgen resistant (aggressive) tumors and also in other prostate and bladder pathology projects.


Qualifications

  • Bachelor of Medical Science (Honours), University of Nottingham - UK
  • Bachelor of Medicine, Bachelor of Surgery, University of Nottingham - UK

Keywords

  • Coeliac Disease
  • Dermatopathology
  • Functional Bowel Disorders
  • GI Pathology
  • Gastrointestinal Disease
  • Pathology
  • Uropathology

Fields of Research

Code Description Percentage
110316 Pathology (excl. Oral Pathology) 100

Professional Experience

UON Appointment

Title Organisation / Department
Professor of Anatomical Pathology University of Newcastle
School of Medicine and Public Health
Australia

Academic appointment

Dates Title Organisation / Department
1/01/2011 -  Conjoint Associate Professor The University of New South Wales
Australia
1/01/2008 -  Honorary Associate Professor The University of Sydney
Australia
1/01/2005 - 31/12/2022 Membership - European Society of Pathology European Society of Pathology
United Kingdom
1/11/2003 -  Trustee Lymphoma Research Trust
United Kingdom
1/01/2001 - 31/12/2022 Membership - British Society of Gastroenterology (Gastroduodenal Section Committee) British Society of Gastroenterology (Gastroduodenal Section Committee)
United Kingdom
1/01/2000 -  Assistant Admissions Tutor Imperial College London
United Kingdom
1/01/1999 -  Membership - British Society for the Study of Vulval Disease British Society for the Study of Vulval Disease
United Kingdom
1/01/1995 -  Membership - Pathology Society of Great Britain Pathology Society of Great Britain
Australia
1/01/1994 -  Membership - British Society of Dermatopathology British Society of Dermatopathology
United Kingdom
1/01/1989 -  Membership - American Gastroenterology Association American Gastroenterological Association
United States
1/01/1985 -  Membership - British Medical Association British Medical Association
United Kingdom
1/10/1984 - 1/10/2003 Senior Lecturer and Honorary Consultant Imperial College London
United Kingdom
1/01/1982 -  Membership - Association of Clinical Pathologists Association of Clinical Pathologists
Australia
1/02/1981 - 1/09/1984 Senior Registrar Imperial College London
United Kingdom
1/12/1979 - 1/01/1981 Research Assistant (Clinical) and Honorary Registrar Imperial College London
United Kingdom
1/09/1977 - 1/11/1979 Lecturer, Honorary SHO and Honorary Registrar Nottingham University
United Kingdom
1/02/1977 - 1/07/1977 Surgical House Officer General Hospital, Nottingham
United Kingdom
1/08/1976 - 1/01/1977 Medical House Officer General Hospital, Nottingham
United Kingdom

Awards

Recognition

Year Award
2006 Excellence in Teaching Award
Imperial College London

Invitations

Participant

Year Title / Rationale
2006 Gastric phenotype as a predictor of gastric cancer?
Organisation: British Society of Gastroenterology Description:
2006 Is “CLO and go” enough to diagnose H. pylori infection?
Organisation: European Helicobacter Study Group Description: Chair: Pathology and Carcinogenesis Workshop

Speaker

Year Title / Rationale
2012 Coeliac Symposium: What is Lymphocytic Duodenosis?
Organisation: British Society of Gastroenterology Description: Digestive Disease Foundation meeting
2012 Eosinophils and Mast Cells in Functional Gastrointestinal Disorders
Organisation: Nottingham GI Research Group
2011 Organ Defined Eosinophilia
Organisation: West London Rheumatology Group
2010 Infection and Gastrointestinal cancer: mechanisms and therapeutic strategies - Is inflammation essential for pathogen induced carcinogenesis?
Organisation: British Society of Gastroenterology
2010 The Kalixanda Study and GI Eosinophilia.
Organisation: John Hunter Hospital/ Nepean Hospital
2010 Symposium on GI Eosinophilia: Paediatric Eosinophilia
Organisation: European Congress of Pathology
2009 D2? Coeliac – histology or serology for diagnosis?
Organisation: British Society of Gastroenterology
2009 Short course: Gastrointestinal Infections: Upper GI Infections – What else besides Helicobacter pylori?
Organisation: European Congress of Pathology
2008 The Kalixanda Study & Eosinophils in the Upper Gastrointestinal Tract
Organisation: Mayo Clinic
2008 Gastroduodenal Symposium Gastric Lumps and Bumps; How Can Pathology Help?
Organisation: British Society of Gastroenterology
2007 Unusual forms of gastritis: Eosinophilic gastritis
Organisation: European Congress of Pathology
2005 GI infections
Organisation: European Congress of Pathology
2004 Diagnostic Dilemmas in Dysplasia – The Viennese Waltz
Organisation: British Society of Gastroenterology
2004 Gastrointestinal Pathology: Intestinal Metaplasia in the oesophagus and stomach – the clinical value of reporting, classification and follow up.
Organisation: Cellular Pathology Update Study Day
2004 Eosinophilic Gastrointestinal Disease
Organisation: British Society of Allergy and Clinical Immunology
2004 Lectures and slide seminars on gastroduodenal inflammatory pathology
Organisation: European Society of Pathology
2003 Barrett’s Oesophagus – a pathologist’s viewpoint
Organisation: British Oesophageal Group
2003 Endoscopic pathology & Intestinal Metaplasia in the Stomach and Duodenum
Organisation: Oxford GI group
2003 Barrett’s oesophagus
Organisation: Chelsea and Westminster GI group
2003 Current Problems in Gastrointestinal Tract Pathology, Classification of Duodenitis
Organisation: European Congress of Pathology
2001 Reporting Gastritis
Organisation: Association of Clinical Pathologists
2000 Intestinal Metaplasia and Dysplasia in the Stomach, Diagnostic Difficulties and Clinical Consequences
Organisation: International Academy of Pathology
Edit

Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Book (1 outputs)

Year Citation Altmetrics Link
2000 Walker M, Thursz M, Teare J, Brian F, Upper Gastrointestinal Tract: Ulcers and Inflammation (Practical Endoscopy and Pathology), Wiley-Blackwell, Oxford, United Kingdom, 96 (2000) [A2]

Chapter (2 outputs)

Year Citation Altmetrics Link
2004 Walker M, Talley NJ, 'Duodenitis', Encyclopedia of Gastroenterology, Elsevier, San Diego, United States 653-654 (2004) [B1]
DOI 10.1016/B0-12-386860-2/00199-4
Co-authors Nicholas Talley
1995 Ridley M, Walker M, 'Normal variants of external genital morphology', Genital skin disorders : a guide to non-sexually transmitted conditions, Chapman &? Hall Medical, London, United Kingdom 1-8 (1995) [B1]

Journal article (191 outputs)

Year Citation Altmetrics Link
2015 Walker MM, Talley NJ, Inganäs L, Engstrand L, Jones MP, Nyhlin H, et al., 'Colonic spirochetosis is associated with colonic eosinophilia and irritable bowel syndrome in a general population in Sweden', Human Pathology, 46 277-283 (2015)

Irritable bowel syndrome (IBS) is a functional disorder defined by symptoms in the absence of overt pathology. Colonic spirochetosis (CS), defined by histologic observation of spi... [more]

Irritable bowel syndrome (IBS) is a functional disorder defined by symptoms in the absence of overt pathology. Colonic spirochetosis (CS), defined by histologic observation of spirochetal strains of Brachyspira in colonic biopsies, is uncommon and considered of doubtful significance. We aimed to determine the prevalence of CS in the general population, identify subtle colon pathologies, and evaluate a link with symptoms of IBS. Colonoscopy was performed in 745 subjects (aged 19-70 years, mean age 51 years, 43% male) with biopsies (ileum and 4 colonic sites) from a random population sample, Stockholm, Sweden, who completed a validated questionnaire of gastrointestinal symptoms; IBS was identified by Rome III criteria. CS was identified by histology and immunohistochemistry. In a general population, 17 individuals (2.28%; 95% confidence interval, 1.2%-3.5%) were diagnosed as having CS by histology; 6 (35%) had IBS. CS was always present in the sigmoid colon, but only 14 rectal biopsies. Eosinophils were increased in colon biopsies in CS cases versus controls, in the transverse (P =.02), sigmoid colon (P =.001), and rectum (P =.0005) with subepithelial eosinophil clusters (P =.053). Lymphoid follicles (at any site) were present in 13 CS (P =.0003). There was a 3-fold increased risk of IBS in CS (odds ratio, 3.59; 95% confidence interval, 1.27-10.11; P =.015). Polyps and diverticular disease were similar in CS cases and controls. The prevalence of CS in a general population is 2% and associated with nonconstipating IBS. Colonic eosinophilia with lymphoid follicles may signify the presence of CS.

DOI 10.1016/j.humpath.2014.10.026
Citations Scopus - 2Web of Science - 2
Co-authors Nicholas Talley
2015 Walker MM, Talley NJ, Inganäs L, Engstrand L, Jones MP, Nyhlin H, et al., 'Colonic spirochetosis is associated with colonic eosinophilia and irritable bowel syndrome in a general population in Sweden', Human Pathology, 46 277-283 (2015)
DOI 10.1016/j.humpath.2014.10.026
Co-authors Nicholas Talley
2015 Zala AV, Walker MM, Talley NJ, 'Emerging drugs for functional dyspepsia.', Expert Opin Emerg Drugs, 20 221-233 (2015)
DOI 10.1517/14728214.2015.1009827
Citations Scopus - 2
Co-authors Nicholas Talley
2015 Marks E, Goggins BJ, Cardona J, Cole S, Minahan K, Mateer S, et al., 'Oral delivery of prolyl hydroxylase inhibitor: AKB-4924 promotes localized mucosal healing in a mouse model of colitis.', Inflamm Bowel Dis, 21 267-275 (2015)
DOI 10.1097/MIB.0000000000000277
Co-authors Simon Keely
2015 Pundavela J, Roselli S, Faulkner S, Attia J, Scott RJ, Thorne RF, et al., 'Nerve fibers infiltrate the tumor microenvironment and are associated with nerve growth factor production and lymph node invasion in breast cancer', Molecular Oncology, (2015)

Infiltration of the tumor microenvironment by nerve fibers is an understudied aspect of breast carcinogenesis. In this study, the presence of nerve fibers was investigated in a co... [more]

Infiltration of the tumor microenvironment by nerve fibers is an understudied aspect of breast carcinogenesis. In this study, the presence of nerve fibers was investigated in a cohort of 369 primary breast cancers (ductal carcinomas in situ, invasive ductal and lobular carcinomas) by immunohistochemistry for the neuronal marker PGP9.5. Isolated nerve fibers (axons) were detected in 28% of invasive ductal carcinomas as compared to only 12% of invasive lobular carcinomas and 8% of ductal carcinomas in situ (p=0.0003). In invasive breast cancers, the presence of nerve fibers was observed in 15% of lymph node negative tumors and 28% of lymph node positive tumors (p=0.0031), indicating a relationship with the metastatic potential. In addition, there was an association between the presence of nerve fibers and the expression of nerve growth factor (NGF) in cancer cells (p=0.0001). Invitro, breast cancer cells were able to induce neurite outgrowth in PC12 cells, and this neurotrophic activity was partially inhibited by anti-NGF blocking antibodies. In conclusion, infiltration by nerve fibers is a feature of the tumor microenvironment that is associated with aggressiveness and involves NGF production by cancer cells. The potential participation of nerve fibers in breast cancer progression needs to be further considered.

DOI 10.1016/j.molonc.2015.05.001
Co-authors Phillip Jobling, John Attia, Hubert Hondermarck, Rick Thorne, Rodney Scott, John Forbes
2015 Talley NJ, Holtmann G, Walker MM, 'Therapeutic strategies for functional dyspepsia and irritable bowel syndrome based on pathophysiology', Journal of Gastroenterology, 50 601-613 (2015)

Functional gastrointestinal disorders (FGIDs) are common and distressing. They are so named because a defined pathophysiology in terms of structural or biochemical pathways is lac... [more]

Functional gastrointestinal disorders (FGIDs) are common and distressing. They are so named because a defined pathophysiology in terms of structural or biochemical pathways is lacking. Traditionally FGIDs have been conceptualized as brain¿gut disorders, with subgroups of patients demonstrating visceral hypersensitivity and motility abnormalities as well as psychological distress. However, it is becoming apparent that there are certain structural or biochemical gut alterations among subsets with the common FGIDs, most notably functional dyspepsia (FD) and irritable bowel syndrome (IBS). For example, a sodium channel mutation has been identified in IBS that may account for 2¿% of cases, and subtle intestinal inflammation has been observed in both IBS and FD. Other research has implicated early life events and stress, autoimmune disorders and atopy and infections, the gut microbiome and disordered mucosal immune activation in patients with IBS or FD. Understanding the origin of symptoms in FGIDs will allow therapy to be targeted at the pathophysiological changes, not at merely alleviating symptoms, and holds hope for eventual cure in some cases. For example, there are promising developments in manipulating the microbiome through diet, prebiotics and antibiotics in IBS, and testing and treating patients for Helicobacter pylori infection remains a mainstay of therapy in patients with dyspepsia and this infection. Locally acting drugs such as linaclotide have been an advance in treating the symptoms of constipation-predominant IBS, but do not alter the natural history of the disease. A role for a holistic approach to patients with FGIDs is warranted, as brain-to-gut and gut-to-brain pathways appear to be activated.

DOI 10.1007/s00535-015-1076-x
Citations Scopus - 1
Co-authors Nicholas Talley
2015 Jobling P, Pundavela J, Oliveira SM, Roselli S, Walker MM, Hondermarck H, 'Nerve-Cancer Cell Cross-talk: A Novel Promoter of Tumor Progression.', Cancer Res, 75 1777-1781 (2015)
DOI 10.1158/0008-5472.CAN-14-3180
Co-authors Hubert Hondermarck, Phillip Jobling
2015 Koloski NA, Jones M, Weltman M, Kalantar J, Bone C, Gowryshankar A, et al., 'Identification of early environmental risk factors for irritable bowel syndrome and dyspepsia.', Neurogastroenterol Motil, 27 1317-1325 (2015)
DOI 10.1111/nmo.12626
Co-authors Nicholas Talley
2015 Talley NJ, Holtmann G, Walker MM, 'Therapeutic strategies for functional dyspepsia and irritable bowel syndrome based on pathophysiology.', J Gastroenterol, 50 601-613 (2015)
DOI 10.1007/s00535-015-1076-x
Co-authors Nicholas Talley
2015 Talley NJ, Holtmann G, Walker MM, 'Therapeutic strategies for functional dyspepsia and irritable bowel syndrome based on pathophysiology', Journal of Gastroenterology, 50 601-613 (2015)

Functional gastrointestinal disorders (FGIDs) are common and distressing. They are so named because a defined pathophysiology in terms of structural or biochemical pathways is lac... [more]

Functional gastrointestinal disorders (FGIDs) are common and distressing. They are so named because a defined pathophysiology in terms of structural or biochemical pathways is lacking. Traditionally FGIDs have been conceptualized as brain¿gut disorders, with subgroups of patients demonstrating visceral hypersensitivity and motility abnormalities as well as psychological distress. However, it is becoming apparent that there are certain structural or biochemical gut alterations among subsets with the common FGIDs, most notably functional dyspepsia (FD) and irritable bowel syndrome (IBS). For example, a sodium channel mutation has been identified in IBS that may account for 2¿% of cases, and subtle intestinal inflammation has been observed in both IBS and FD. Other research has implicated early life events and stress, autoimmune disorders and atopy and infections, the gut microbiome and disordered mucosal immune activation in patients with IBS or FD. Understanding the origin of symptoms in FGIDs will allow therapy to be targeted at the pathophysiological changes, not at merely alleviating symptoms, and holds hope for eventual cure in some cases. For example, there are promising developments in manipulating the microbiome through diet, prebiotics and antibiotics in IBS, and testing and treating patients for Helicobacter pylori infection remains a mainstay of therapy in patients with dyspepsia and this infection. Locally acting drugs such as linaclotide have been an advance in treating the symptoms of constipation-predominant IBS, but do not alter the natural history of the disease. A role for a holistic approach to patients with FGIDs is warranted, as brain-to-gut and gut-to-brain pathways appear to be activated.

DOI 10.1007/s00535-015-1076-x
Citations Scopus - 1
Co-authors Nicholas Talley
2015 Roselli S, Pundavela J, Demont Y, Faulkner S, Keene S, Attia J, et al., 'Sortilin is associated with breast cancer aggressiveness and contributes to tumor cell adhesion and invasion.', Oncotarget, 6 10473-10486 (2015)
Co-authors Hubert Hondermarck, Xu Zhang, John Attia
2014 Pundavela J, Demont Y, Jobling P, Lincz LF, Roselli S, Thorne RF, et al., 'ProNGF correlates with Gleason score and is a potential driver of nerve infiltration in prostate cancer', American Journal of Pathology, 184 3156-3162 (2014) [C1]

Nerve infiltration is essential to prostate cancer progression, but the mechanism by which nerves are attracted to prostate tumors remains unknown. We report that the precursor of... [more]

Nerve infiltration is essential to prostate cancer progression, but the mechanism by which nerves are attracted to prostate tumors remains unknown. We report that the precursor of nerve growth factor (proNGF) is overexpressed in prostate cancer and involved in the ability of prostate cancer cells to induce axonogenesis. A series of 120 prostate cancer and benign prostate hyperplasia (BPH) samples were analyzed by IHC for proNGF. ProNGF was mainly localized in the cytoplasm of epithelial cells, with marked expression in cancer compared with BPH. Importantly, the proNGF level positively correlated with the Gleason score (n = 104, tB = 0.51). A higher level of proNGF was observed in tumors with a Gleason score of =8 compared with a Gleason score of 7 and 6 (P < 0.001). In vitro, proNGF was detected in LNCaP, DU145, and PC-3 prostate cancer cells and BPH-1 cells but not in RWPE-1 immortalized nontumorigenic prostate epithelial cells or primary normal prostate epithelial cells. Co-culture of PC12 neuronal-like cells or 50B11 neurons with PC-3 cells resulted in neurite outgrowth in neuronal cells that was inhibited by blocking antibodies against proNGF, indicating that prostate cancer cells can induce axonogenesis via secretion of proNGF. These data reveal that ProNGF is a biomarker associated with high-risk prostate cancers and a potential driver of infiltration by nerves.

DOI 10.1016/j.ajpath.2014.08.009
Citations Scopus - 2Web of Science - 2
Co-authors Hubert Hondermarck, Lisa Lincz, Phillip Jobling, Rick Thorne
2014 Ludvigsson JF, Bai JC, Biagi F, Card TR, Ciacci C, Ciclitira PJ, et al., 'Diagnosis and management of adult coeliac disease: Guidelines from the British society of gastroenterology', Gut, 63 1210-1228 (2014) [C1]

A multidisciplinary panel of 18 physicians and 3 nonphysicians from eight countries (Sweden, UK, Argentina, Australia, Italy, Finland, Norway and the USA) reviewed the literature ... [more]

A multidisciplinary panel of 18 physicians and 3 nonphysicians from eight countries (Sweden, UK, Argentina, Australia, Italy, Finland, Norway and the USA) reviewed the literature on diagnosis and management of adult coeliac disease (CD). This paper presents the recommendations of the British Society of Gastroenterology. Areas of controversies were explored through phone meetings and web surveys. Nine working groups examined the following areas of CD diagnosis and management: classification of CD; genetics and immunology; diagnostics; serology and endoscopy; follow-up; gluten-free diet; refractory CD and malignancies; quality of life; novel treatments; patient support; and screening for CD.

DOI 10.1136/gutjnl-2013-306578
Citations Scopus - 36Web of Science - 37
2014 Ludvigsson JF, Bai JC, Biagi F, Card TR, Ciacci C, Zingone F, et al., 'Diagnosis and management of adult coeliac disease: Guidelines from the British society of gastroenterology', Gut, 63 1210-1228 (2014)
DOI 10.1136/gutjnl-2013-306578
Citations Scopus - 1
2014 Collison AM, Sokulsky LA, Sherrill JD, Nightingale S, Hatchwell L, Talley NJ, et al., 'TNF-related apoptosis-inducing ligand (TRAIL) regulates midline-1, thymic stromal lymphopoietin, inflammation, andremodeling in experimental eosinophilic esophagitis', Journal of Allergy and Clinical Immunology, (2014)

Background: Eosinophilic esophagitis (EoE) is an inflammatory disorder of the esophagus defined by eosinophil infiltration and tissue remodeling with resulting symptoms of esophag... [more]

Background: Eosinophilic esophagitis (EoE) is an inflammatory disorder of the esophagus defined by eosinophil infiltration and tissue remodeling with resulting symptoms of esophageal dysfunction. TNF-related apoptosis-inducing ligand (TRAIL) promotes inflammation through upregulation of the E3 ubiquitin-ligase midline-1 (MID1), which binds to and deactivates the catalytic subunit of protein phosphatase 2Ac, resulting in increased nuclear factor ¿B activation. Objective: We sought to elucidate the role of TRAIL in EoE. Methods: We used Aspergillus fumigatus to induce EoE in TRAIL-sufficient (wild-type) and TRAIL-deficient (TRAIL-/-) mice and targeted MID1 in the esophagus with small interfering RNA. We also treated mice with recombinant thymic stromal lymphopoietin (TSLP) and TRAIL. Results: TRAIL deficiency and MID1 silencing with small interfering RNA reduced esophageal eosinophil and mast cell numbers and protected against esophageal circumference enlargement, muscularis externa thickening, and collagen deposition. MID1 expression and nuclear factor ¿B activation were reduced in TRAIL-/- mice, whereas protein phosphatase 2Ac levels were increased compared with those seen in wild-type control mice. This was associated with reduced expression of CCL24, CCL11, CCL20, IL-5, IL-13, IL-25, TGFB, and TSLP. Treatment with TSLP reconstituted hallmark features of EoE in TRAIL-/- mice and recombinant TRAIL induced esophageal TSLP expression invivo in the absence of allergen. Post hoc analysis of gene array data demonstrated significant upregulation of TRAIL and MID1 in a cohort of children withEoE compared with that seen in controls. Conclusion: TRAIL regulates MID1 and TSLP, inflammation, fibrosis, smooth muscle hypertrophy, and expression ofinflammatory effector chemokines and cytokines inexperimental EoE.

DOI 10.1016/j.jaci.2015.03.031
Co-authors Joerg Mattes, Nicholas Talley
2014 Ford AC, Talley NJ, Walker MM, Jones MP, 'Increased prevalence of autoimmune diseases in functional gastrointestinal disorders: case-control study of 23 471 primary care patients', ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 40 827-834 (2014) [C1]
DOI 10.1111/apt.12903
Citations Scopus - 1Web of Science - 1
Co-authors Nicholas Talley
2014 Walker MM, Talley NJ, 'Review article: Bacteria and pathogenesis of disease in the upper gastrointestinal tract - Beyond the era of Helicobacter pylori', Alimentary Pharmacology and Therapeutics, 39 767-779 (2014)
DOI 10.1111/apt.12666
Citations Scopus - 3
Co-authors Nicholas Talley
2014 Walker MM, Talley NJ, 'Review article: Bacteria and pathogenesis of disease in the upper gastrointestinal tract - Beyond the era of Helicobacter pylori', Alimentary Pharmacology and Therapeutics, 39 767-779 (2014) [C1]

Background Study of the upper gastrointestinal microbiome has shown that other bacteria besides Helicobacter pylori flourish despite the hostile environment. Whilst H. pylori is t... [more]

Background Study of the upper gastrointestinal microbiome has shown that other bacteria besides Helicobacter pylori flourish despite the hostile environment. Whilst H. pylori is the most studied bacteria in this region with a defined role in inflammation and neoplasia, it is apparent that other bacteria may contribute to UGI disease. Aim To review current knowledge of bacteria inhabiting the oesophagus, stomach and duodenum. Methods Published studies on the upper gastrointestinal microbiome (extracted from PubMed during the last 20 years). Results The stomach is a hostile environment for bacteria; however, recent studies categorising the microbiota have shown surprising results. Helicobacter pylori has been intensively studied since 1984 and recent sequencing analysis of other gastric microbiota shows that H. pylori is not alone. Composition can be influenced by acid suppression, gastritis and abundance of H. pylori. Eradication of H. pylori, whilst decreasing gastric cancer is associated with an increase in asthma, reflux and obesity. A future approach may be to selectively eradicate bacteria which predispose to inflammation and cancer as opposed to a comprehensive knockout policy. In the oesophagus, viridans streptococci are the most common bacteria influenced by both oral and gastric bacteria. Oesophagitis and Barrett's oesophagus are characterised by a significant decrease in Gram-positive bacteria and an increase in Gram-negative bacteria. An inverse association of H. pylori and oesophageal adenocarcinoma is described. The duodenal microbiome has been shown to influence small intestinal bacterial overgrowth, irritable bowel syndrome and coeliac disease. The numbers of bacteria recoverable by culture are variable in the stomach mucosa and gastric juice, typically 102-104 colony-forming units (CFU)/g or mL and in the oesophagus, up to 104 bacteria per mm2 mucosal surface. In the small bowel, in health, 103 CFU/mL are normal. Conclusion This review highlights current knowledge of upper gastrointestinal bacteria and associations with disease. © 2014 John Wiley & Sons Ltd.

DOI 10.1111/apt.12666
Citations Scopus - 9Web of Science - 10
Co-authors Nicholas Talley
2014 Walker MM, Harris Diez PR, Crabtree JE, 'Commentary: Duodenal intraepithelial lymphocytosis in children without coeliac disease', Alimentary Pharmacology and Therapeutics, 39 1430-1431 (2014) [C3]
DOI 10.1111/apt.12779
Citations Scopus - 1Web of Science - 1
2014 Jones MP, Walker MM, Ford AC, Talley NJ, 'The overlap of atopy and functional gastrointestinal disorders among 23 471 patients in primary care', Alimentary Pharmacology and Therapeutics, 40 382-391 (2014)
DOI 10.1111/apt.12846
Citations Scopus - 5
Co-authors Nicholas Talley
2014 Jones MP, Walker MM, Ford AC, Talley NJ, 'Editorial: The overlap of atopy and functional gastrointestinal disorders in primary care - Authors' reply', Alimentary Pharmacology and Therapeutics, 40 1244-1245 (2014) [C3]
DOI 10.1111/apt.12961
Co-authors Nicholas Talley
2014 Walker MM, Aggarwal KR, Shim LSE, Bassan M, Kalantar JS, Weltman MD, et al., 'Duodenal eosinophilia and early satiety in functional dyspepsia: Confirmation of a positive association in an Australian cohort', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 29 474-479 (2014) [C1]
DOI 10.1111/jgh.12419
Citations Scopus - 5Web of Science - 2
Co-authors Nicholas Talley
2014 Jones MP, Walker MM, Ford AC, Talley NJ, 'The overlap of atopy and functional gastrointestinal disorders among 23 471 patients in primary care', Alimentary Pharmacology and Therapeutics, 40 382-391 (2014) [C1]

Background Activation of the immune system has been demonstrated in atopy and functional gastrointestinal disorders (FGIDs). Previous data from our group have suggested a connecti... [more]

Background Activation of the immune system has been demonstrated in atopy and functional gastrointestinal disorders (FGIDs). Previous data from our group have suggested a connection between immune dysregulation, FGIDs and mood disorders. Aim To investigate if these data translate to clinical practice and examine connections from the perspective of FGIDs to determine whether atopy and FGIDs are connected via mood disorders. Methods Evidence of irritable bowel syndrome (IBS), functional dyspepsia (FD) and constipation was sought from the medical records of 30 000 primary care records over a minimum 5 year period. The same records yielded diagnoses of four atopic conditions (asthma, eczema, allergic rhinitis/hay fever and conjunctivitis). Results Atopic conditions were found in excess among all FGID groups considered when compared with controls. In the groups with IBS alone (OR = 1.43, 1.29-1.58), FD alone (OR = 1.41, 1.26-1.58) and those with multiple FGIDs (OR = 1.92, 1.75-2.12) there was elevated prevalence of asthma compared with controls without a FGID. Across disorders the excess was generally highest among patients diagnosed with multiple FGIDs (rhinitis/hay fever OR = 3.74, 3.32-4.20; conjunctivitis OR = 3.00, 2.49-3.62) and was only partly explained by a common association between both FGIDs and atopic conditions with mood disorders, although not for every atopic/FGID combination (rhinitis/hay fever OR = 2.60, 2.29-2.96, conjunctivitis OR = 2.34, 1.90-2.87). Conclusions Irritable bowel syndrome, functional dyspepsia and constipation share an association with atopy that is only partly explained via a common connection with mood disorders. These data have important implications for understanding both the pathophysiology of functional gastrointestinal disorders and development of new treatments. © 2014 John Wiley & Sons Ltd.

DOI 10.1111/apt.12846
Citations Scopus - 7Web of Science - 8
Co-authors Nicholas Talley
2014 Walker MM, Powell N, Talley NJ, 'Atopy and the gastrointestinal tract--a review of a common association in unexplained gastrointestinal disease.', Expert Rev Gastroenterol Hepatol, 8 289-299 (2014) [C1]
DOI 10.1586/17474124.2014.881716
Citations Scopus - 6Web of Science - 6
Co-authors Nicholas Talley
2013 Talley NJ, Walker MM, 'Novel insights into the pathology of upper gut symptoms: new syndromes, new diseases.', Med J Aust, 199 440-441 (2013) [C3]
Co-authors Nicholas Talley
2013 Low LCM, Kinderlerer A, Walker MM, Setterfield J, 'A woman with asthma and hemorrhagic bullae', INTERNATIONAL JOURNAL OF DERMATOLOGY, 52 793-794 (2013) [C3]
DOI 10.1111/j.1365-4632.2012.05837.x
2013 Ludvigsson JF, Leffler DA, Bai JC, Biagi F, Fasano A, Green PHR, et al., 'The Oslo definitions for coeliac disease and related terms', GUT, 62 43-52 (2013) [C1]
DOI 10.1136/gutjnl-2011-301346
Citations Scopus - 173Web of Science - 145
2013 Romero D, Kawano Y, Bengoa N, Walker MM, Maltry N, Niehrs C, et al., 'Downregulation of Dickkopf-3 disrupts prostate acinar morphogenesis through TGF-beta/Smad signalling', JOURNAL OF CELL SCIENCE, 126 1858-1867 (2013) [C1]
DOI 10.1242/jcs.119388
Citations Scopus - 6Web of Science - 5
2013 Harris PR, Serrano CA, Villagran A, Walker MM, Thomson M, Duarte I, et al., 'Helicobacter pylori-associated hypochlorhydria in children, and development of iron deficiency', JOURNAL OF CLINICAL PATHOLOGY, 66 343-347 (2013) [C1]
DOI 10.1136/jclinpath-2012-201243
Citations Scopus - 10Web of Science - 8
2013 Ludvigsson JF, Aro P, Walker MM, Vieth M, Agreus L, Talley NJ, et al., 'Celiac disease, eosinophilic esophagitis and gastroesophageal reflux disease, an adult population-based study', SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 48 808-814 (2013) [C1]
DOI 10.3109/00365521.2013.792389
Citations Scopus - 13Web of Science - 9
Co-authors Nicholas Talley
2013 Ludvigsson JF, Leffler DA, Bai JC, Biagi F, Fasano A, Green PHR, et al., 'The Oslo definitions for coeliac disease and related terms', Gut, 62 43-52 (2013) [C1]
DOI 10.1136/gutjnl-2011-301346
Citations Scopus - 219Web of Science - 187
2013 Magalhaes Queiroz DM, Harris PR, Sanderson IR, Windle HJ, Walker MM, Camargos Rocha AM, et al., 'Iron Status and Helicobacter pylori Infection in Symptomatic Children: An International Multi-Centered Study', PLOS ONE, 8 (2013) [C1]
DOI 10.1371/journal.pone.0068833
Citations Scopus - 9Web of Science - 8
2012 Ronkainen J, Walker MM, Aro P, Storskrubb T, Talley NJ, Ahmed ZB, et al., 'Lymphocytic oesophagitis, a condition in search of a disease?', GUT, 61 (2012) [C3]
DOI 10.1136/gutjnl-2012-302329
Citations Web of Science - 4
Co-authors Nicholas Talley
2012 Koloski NA, Jones M, Talley NJ, 'Authors' response', Gut, 61 1776-1777 (2012) [C3]
Citations Scopus - 5Web of Science - 2
Co-authors Nicholas Talley
2012 Darrington RS, Campa VM, Walker M, Bengoa-Vergniory N, Gorrono-Etxebarria I, Uysal-Onganer P, et al., 'Distinct expression and activity of GSK-3a and GSK-3ß in prostate cancer', International Journal of Cancer, 131 E872-E883 (2012) [C1]
DOI 10.1002/ijc.27620
Citations Scopus - 11Web of Science - 11
2012 Sanders DSA, Grabsch H, Harrison R, Bateman A, Going J, Goldin R, et al., 'Comparing virtual with conventional microscopy for the consensus diagnosis of Barrett's neoplasia in the AspECT Barrett's chemoprevention trial pathology audit', Histopathology, 61 795-800 (2012) [C1]
Citations Scopus - 10Web of Science - 8
2012 Low LCM, Carton J, Walker M, Tudor-Williams G, Hardman C, 'Intrauterine Herpes Simplex Virus Infection Presenting with Hypopigmented Lesions', PEDIATRIC DERMATOLOGY, 29 515-517 (2012) [C1]
DOI 10.1111/j.1525-1470.2011.01542.x
Citations Scopus - 2Web of Science - 2
2012 Reebye V, Cano LQ, Lavery DN, Brooke GN, Powell SM, Chotai D, et al., 'Role of the HSP90-associated cochaperone p23 in enhancing activity of the androgen receptor and significance for prostate cancer', Molecular Endocrinology, 26 1694-1706 (2012) [C1]
DOI 10.1210/me.2012-1056
Citations Scopus - 7Web of Science - 5
2012 Walker MM, Woodward J, 'A clinicopathological approach to the diagnosis of coeliac disease', Diagnostic Histopathology, 18 402-410 (2012) [C1]

Coeliac disease is defined as a small bowel enteropathy due to immune mediated damage on exposure to gluten in the diet, occurring in those with a genetic predisposition to this c... [more]

Coeliac disease is defined as a small bowel enteropathy due to immune mediated damage on exposure to gluten in the diet, occurring in those with a genetic predisposition to this condition. Previously considered rare, the prevalence of coeliac disease is increasing due to a genuine rise in incidence and also better detection. The diagnosis of coeliac disease involves many disciplines, presentation is varied and if the diagnosis is delayed there is a risk of poor quality of life and a small increase in malignancy. Serology is a first line test, followed by confirmatory small intestinal biopsy. This review discusses the clinicopathological approach to diagnosis, through serology and biopsy and discusses complications which occur in some individuals, namely refractory coeliac disease and dermatitis herpetiformis. The entity of non-coeliac gluten sensitivity is also entering the spectrum of coeliac diagnosis and may lead to an extension of the diagnostic parameters of coeliac disease. © 2012 Elsevier Ltd.

DOI 10.1016/j.mpdhp.2012.08.011
2012 Mayer EK, Undre S, Cohen DC, Walker MM, Vale JA, Patel A, '"An Unusual Urological Tumour": Above the Collar and below the Belt.', Case reports in oncological medicine, 2012 480826 (2012) [C1]
DOI 10.1155/2012/480826
2012 Fanous RN, Mayer EK, Vale J, Lloyd J, Walker MM, 'Primary renal embryonal rhabdomyosarcoma in adults: a case report and review of the literature.', Case reports in oncological medicine, 2012 460749 (2012) [C1]
DOI 10.1155/2012/460749
2012 Khan MA, Kar A, Walker MM, Lloyd J, Vale JA, Mayer EK, 'A Case of Squamous Cell Carcinoma of the Renal Pelvis in association with Schistosoma hematobium.', Case reports in oncological medicine, 2012 352401 (2012) [C1]
DOI 10.1155/2012/352401
2011 Walker MM, Warwick A, Ung C, Talley NJ, 'The role of eosinophils and mast cells in intestinal functional disease', Current Gastroenterology Reports, 13 323-330 (2011) [C1]
DOI 10.1007/s11894-011-0197-5
Citations Scopus - 26
Co-authors Nicholas Talley
2011 Robinson MJ, Tuke PW, Erlwein O, Tettmar KI, Kaye S, Naresh KN, et al., 'No Evidence of XMRV or MuLV Sequences in Prostate Cancer, Diffuse Large B-Cell Lymphoma, or the UK Blood Donor Population.', Advances in Virology, 2011 1-6 (2011) [C1]
DOI 10.1155/2011/782353
Citations Scopus - 10
2011 Brooke GN, Culley RL, Dart DA, Mann DJ, Gaughan L, McCracken SR, et al., 'FUS/TLS is a novel mediator of androgen-dependent cell-cycle progression and prostate cancer growth', Cancer Research, 71 914-924 (2011) [C1]
DOI 10.1158/0008-5472.CAN-10-0874
Citations Scopus - 15Web of Science - 14
2011 Lavery DN, Villaronga MA, Walker M, Patel A, Belandia B, Bevan CL, 'Repression of androgen receptor activity by HEYL, a third member of the hairy/enhancer-of-split-related family of Notch effectors', Journal of Biological Chemistry, 286 7796-7808 (2011) [C1]
DOI 10.1074/jbc.M110.198655
Citations Scopus - 12Web of Science - 12
2011 Walker MM, Talley NJ, 'Clinical value of duodenal biopsies - Beyond the diagnosis of coeliac disease', Pathology Research and Practice, 207 538-544 (2011) [C2]
DOI 10.1016/j.prp.2011.08.001
Citations Scopus - 11Web of Science - 8
Co-authors Nicholas Talley
2010 Uysal-Onganer P, Kawano Y, Caro M, Walker M, Diez S, Darrington RS, et al., 'Wnt-11 promotes neuroendocrine-likedifferentiation, survival and migration of prostatecancer cells.', Molecular Cancer, 9 55-65 (2010) [C1]
DOI 10.1186/1476-4598-9-55
Citations Scopus - 45Web of Science - 36
2010 Robinson MJ, Erlwein OW, Kaye S, Weber J, Cingoz O, Patel A, et al., 'Mouse DNA contamination in human tissue tested for XMRV', Retrovirology, 7 108-108 (2010) [C1]
DOI 10.1186/1742-4690-7-108
Citations Scopus - 93Web of Science - 80
2010 Walker M, Murray JA, Ronkainen J, Aro P, Storskrubb T, D'Amato M, et al., 'Detection of Celiac Disease and Lymphocytic Enteropathy by Parallel Serology and Histopathology in a Population-Based Study', Gastroenterology, 139 112-119 (2010) [C1]
DOI 10.1053/j.gastro.2010.04.007
Citations Scopus - 96Web of Science - 86
Co-authors Nicholas Talley
2010 Khamri W, Walker M, Clark P, Atherton JC, Thursz MR, Bamford KB, et al., 'Helicobacter pylori stimulates dendritic cells to induce interleukin-17 expression from CD4+ T lymphocytes', Infection and Immunity, 78 845-853 (2010) [C1]
DOI 10.1128/IAI.00524-09
Citations Scopus - 42Web of Science - 32
2010 Walker M, Salehian SS, Murray CE, Rajendran A, Hoare JM, Negus R, et al., 'Implications of eosinophilia in the normal duodenal biopsy - An association with allergy and functional dyspepsia', Alimentary Pharmacology and Therapeutics, 31 1229-1236 (2010) [C1]
DOI 10.1111/j.1365-2036.2010.04282.x
Citations Scopus - 37Web of Science - 28
Co-authors Nicholas Talley
2009 Walker M, Talley NJ, Prabhakar M, Pennaneac'H CJ, Aro P, Ronkainen J, et al., 'Duodenal mastocytosis, eosinophilia and intraepithelial lymphocytosis as possible disease markers in the irritable bowel syndrome and functional dyspepsia', Alimentary Pharmacology and Therapeutics, 29 765-773 (2009) [C1]
DOI 10.1111/j.1365-2036.2009.03937.x
Citations Scopus - 81Web of Science - 68
Co-authors Nicholas Talley
2009 Kogianni G, Walker M, Waxman J, Sturge J, 'Endo180 expression with cofunctional partners MT1-MMP and uPAR-uPA is correlated with prostate cancer progression', European Journal of Cancer, 45 685-693 (2009) [C1]
DOI 10.1016/j.ejca.2008.11.023
Citations Scopus - 19Web of Science - 19
2008 Diss JKJ, Fraser SP, Walker M, Patel A, Latchman DS, Djamgoz MBA, 'ß-Subunits of voltage-gated sodium channels in human prostate cancer: Quantitative in vitro and in vivo analyses of mRNA expression', Prostate Cancer and Prostatic Diseases, 11 325-333 (2008) [C1]
DOI 10.1038/sj.pcan.4501012
Citations Scopus - 19Web of Science - 18
2008 Walker M, Teare L, McNulty C, 'Gastric cancer and Helicobacter pylori: The bug, the host or the environment?', Postgraduate Medical Journal, 84 169-170 (2008) [C3]
DOI 10.1136/pgmj.2008.068346
Citations Scopus - 4Web of Science - 3
2008 Storskrubb T, Aro P, Ronkainen J, Sipponen P, Nyhlin H, Talley NJ, et al., 'Serum biomarkers provide an accurate method for diagnosis of atrophic gastritis in a general population: The Kalixanda study', Scandinavian Journal of Gastroenterology, 43 1448-1455 (2008) [C1]
DOI 10.1080/00365520802273025
Citations Scopus - 52Web of Science - 47
Co-authors Nicholas Talley
2008 Walker M, Ellis SM, Auza MJ, Patel A, Clark P, 'The intercellular adhesion molecule, cadherin-10, is a marker for human prostate luminal epithelial cells that is not expressed in prostate cancer', Modern Pathology, 21 85-95 (2008) [C1]
DOI 10.1038/modpathol.3800988
Citations Scopus - 9Web of Science - 8
2007 Khamri W, Worku ML, Anderson AE, Walker M, Hawgood S, Reid KBM, et al., 'Helicobacter infection in the surfactant protein D-deficient mouse', Helicobacter (Oxford), 12 112-123 (2007) [C1]
DOI 10.1111/j.1523-5378.2007.00480.x
Citations Scopus - 7Web of Science - 7
2007 Ronkainen J, Storskrubb T, Hindley LA, Harmsen WS, Zinsmeister AR, Agreus L, et al., 'Non-ulcer Dyspepsia and Duodenal Eosinophilia: An Adult Endoscopic Population-Based Case-Control Study', Clinical Gastroenterology and Hepatology, 5 1175-1183 (2007) [C1]
DOI 10.1016/j.cgh.2007.05.015
Citations Scopus - 82Web of Science - 72
Co-authors Nicholas Talley
2007 Anderson AE, Worku ML, Khamri W, Bamford KB, Walker M, Thursz MR, 'TLR9 polymorphisms determine murine lymphocyte responses to Helicobacter: Results from a genome-wide scan', European Journal of Immunology, 37 1548-1561 (2007) [C1]
DOI 10.1002/eji.200636562
Citations Scopus - 11Web of Science - 11
2007 Ronkainen J, Talley NJ, Aro P, Storskrubb T, Johansson S-E, Lind T, et al., 'Prevalence of oesophageal eosinophils and eosinophilic oesophagitis in adults: The population-based Kalixanda study', Gut, 56 615-620 (2007) [C1]
DOI 10.1136/gut.2006.107714
Citations Scopus - 158Web of Science - 130
Co-authors Nicholas Talley
2006 Kawano Y, Kitaoka M, Hamada Y, Walker M, Waxman J, Kypta RM, 'Regulation of prostate cell growth and morphogenesis by Dickkopf-3', Oncogene, 25 6528-6539 (2006) [C1]
DOI 10.1038/sj.onc.1209661
Citations Scopus - 71Web of Science - 62
2006 Diss JKJ, Faulkes DJ, Walker MM, Patel A, Foster CS, Budhram-Mahadeo V, et al., 'Brn-3a neuronal transcription factor functional expression in human prostate cancer', PROSTATE CANCER AND PROSTATIC DISEASES, 9 83-91 (2006)
DOI 10.1038/sj.pcan.4500837
Citations Scopus - 14Web of Science - 14
2006 Rowe EWJ, Laniado ME, Walker M, Anup P, 'Incidental acute prostatic inflammation is associated with a lower percentage of free prostate-specific antigen than other benign conditions of the prostate: A prospective screening study', BJU International, 97 1039-1042 (2006) [C1]
DOI 10.1111/j.1464-410X.2006.06132.x
Citations Web of Science - 3
2005 Khamri W, Moran AP, Worku ML, Karim QN, Walker M, Annuk H, et al., 'Variations in Helicobacter pylori lipopolysaccharide to evade the innate immune component surfactant protein D', Infection and Immunity, 73 7677-7686 (2005) [C1]
DOI 10.1128/IAI.73.11.7677-7686.2005
Citations Scopus - 39Web of Science - 38
2005 Belandia B, Powell SM, Garcia-Pedrero JM, Walker M, Bevan CL, Parker MG, 'Hey1, a mediator of Notch signaling, is an androgen receptor corepressor', Molecular and Cellular Biology, 25 1425-1436 (2005) [C1]
DOI 10.1128/MCB.25.4.1425-1436.2005
Citations Scopus - 71Web of Science - 66
2005 Moran AP, Khamri W, Walker M, Thursz MR, 'Role of surfactant protein D (SP-D) in innate immunity in the gastric mucosa: Evidence of interaction with Helicobacter pylori lipopolysaccharide', Journal of Endotoxin Research, 11 357-362 (2005) [C1]
DOI 10.1179/096805105X76832
Citations Scopus - 11Web of Science - 11
2005 Diss JKJ, Stewart D, Pani F, Foster CS, Walker M, Patel A, Djamgoz MBA, 'A potential novel marker for human prostate cancer: Voltage-gated sodium channel expression in vivo', Prostate Cancer and Prostatic Diseases, 8 266-273 (2005) [C1]
DOI 10.1038/sj.pcan.4500796
Citations Scopus - 82Web of Science - 70
2005 Smith RD, Tran-Dang MA, Khoubehi B, Witherow R, Patel A, Walker MM, 'Stromal nodules and vessel wall proliferation in TURP specimens are associated with failure of medical therapy with alpha blockers', BJU INTERNATIONAL, 95 76-76 (2005)
2005 Rowe EWJ, Laniado ME, Walker M, Patel A, 'Prostate cancer detection in men with a 'normal' total prostate-specific antigen (PSA) level using percentage free PSA: A prospective screening study', BJU International, 95 1249-1252 (2005) [C1]
DOI 10.1111/j.1464-410X.2005.05514.x
Citations Web of Science - 2
2004 Zhu H, Mazor M, Kawano Y, Walker M, Leung HY, Armstrong K, et al., 'Analysis of Wnt gene expression in prostate cancer: Mutual inhibition by WNT11 and the androgen receptor', Cancer Research, 64 7918-7926 (2004) [C1]
DOI 10.1158/0008-5472.CAN-04-2704
Citations Scopus - 69Web of Science - 60
2004 Dave U, Thursz MR, Ebrahim HY, Burke MM, Townsend ER, Walker M, 'Distribution of laminins in the basement membranes of the upper gastrointestinal tract and Barrett's oesophagus', Journal of Pathology, 202 299-304 (2004) [C1]
DOI 10.1002/path.1526
Citations Scopus - 3Web of Science - 3
2004 Swinn MJ, Walker M, Harbin LJ, Adshead JM, Witherow RO, Vale JA, Patel A, 'Biopsy of the red patch at cystoscopy: Is it worthwhile?', European Urology, 45 471-474 (2004) [C1]
DOI 10.1016/j.eururo.2003.11.019
Citations Scopus - 16Web of Science - 14
2004 Dave U, Taylor-Robinson SD, Walker M, Mahon M, Puri BK, Thursz MR, et al., 'In vitro 1H-magnetic resonance spectroscopy of Barrett's esophageal mucosa using magic angle spinning techniques', European Journal of Gastroenterology and Hepatology, 16 1199-1205 (2004) [C1]
DOI 10.1097/00042737-200411000-00019
Citations Scopus - 9Web of Science - 8
2004 Hemmaway C, Walker M, Deal J, Matutes E, Bain BJ, 'Teaching cases from the Royal Marsden and St Mary's Hospitals case 25. A young boy with massive bilateral renal enlargement', Leukemia and Lymphoma, 45 1301-1303 (2004) [C1]
DOI 10.1080/10428190310001657822
Citations Web of Science - 2
2003 Laniado ME, McMullen I, Walker M, Patel A, 'Use and rationale of a multicompartment microcassette for site-specific biopsies of the prostate in a consecutive cohort of men', Prostate Cancer and Prostatic Diseases, 6 50-52 (2003) [C1]
DOI 10.1038/sj.pcan.4500624
Citations Web of Science - 4
2003 Jenks PJ, Jeremy AHT, Robinson PA, Walker M, Crabtree JE, 'Long-term infection with Helicobacter felis and inactivation of the tumour suppressor gene p53 cumulatively enhance the gastric mutation frequency in Big Blue® transgenic mice', Journal of Pathology, 201 596-602 (2003) [C1]
DOI 10.1002/path.1488
Citations Scopus - 25Web of Science - 20
2003 Walker M, 'What is tropical sprue?', Journal of Gastroenterology and Hepatology, 18 887-890 (2003) [C3]
DOI 10.1046/j.1440-1746.2003.03127.x
Citations Scopus - 22Web of Science - 13
2002 Crabtree JE, Court M, Walker MM, Wang JT, Coulson PS, Coggle S, et al., 'The effects of chronic schistosomiasis on murine Helicobacter gastric epithelial cell proliferation.', GASTROENTEROLOGY, 122 A226-A226 (2002)
2002 Walker MM, Negus RP, Rice A, Loh V, Teare J, Thursz MR, 'Gastric biopsy: Where from and how many using the updated Sydney system to evaluate gastritis, atrophy and intestinal metaplasia?', GASTROENTEROLOGY, 122 A332-A332 (2002)
2002 Walker MM, Marshall JC, Morgan MY, 'Helicobacter pylori (Hp) infection in alcohol misusers: Dyspepsia, endoscopy and gastroduodenal pathology.', GASTROENTEROLOGY, 122 A475-A476 (2002)
2002 Walker MM, Negus RP, Rice A, Loh V, Teare J, Thursz MR, 'Gastric biopsy: Where from and how many using the updated Sydney system to evaluate gastritis, atrophy, and intestinal metaplasia?', GUT, 50 A104-A104 (2002)
2002 Dave U, Walker MM, Ebrahim H, Townsend E, Burke M, Thursz MR, 'Laminins: Distribution in normal upper GI tract and Barrett's oesophagus', GUT, 50 A125-A125 (2002)
2002 Murray E, Khamri W, Walker M, Eggleton P, Moran AP, Ferris JA, et al., 'Expression of surfactant protein D in the human gastric mucosa and during Helicobacter pylori infection', Infection and Immunity, 70 1481-1487 (2002) [C1]
DOI 10.1128/IAI.70.3.1481-1487.2002
Citations Web of Science - 39
2002 Osborn M, Pelling N, Walker M, Fisher C, Nicholson AG, 'The value of 'mesothelium-associated' antibodies in distinguishing between metastatic renal cell carcinomas and mesotheliomas', Histopathology, 41 301-307 (2002) [C1]
DOI 10.1046/j.1365-2559.2002.01527.x
Citations Web of Science - 14
2002 Walker M, 'Cyclooxygenase-2 expression in early gastric cancer, intestinal metaplasia and Helicobacter pylori infection', European Journal of Gastroenterology and Hepatology, 14 347-349 (2002) [C3]
DOI 10.1097/00042737-200204000-00001
Citations Web of Science - 12
2002 Walker M, 'Gleason score on biopsy: Is it reliable for predicting the final grade on pathology? (Editorial comment )', BMJ: British Medical Journal, 90 698-699 (2002) [C3]
DOI 10.1046/j.1464-410X.2002.t01-1-02990.x
2002 Walker M, Worku M, Coggle S, Thursz MR, 'A novel method for assessing gastritis in the murine model demonstrates genetically determined variation in response to Helicobacter felis infection', Helicobacter (Oxford), 7 265-268 (2002) [C1]
DOI 10.1046/j.1523-5378.2002.00091.x
Citations Scopus - 10Web of Science - 8
2001 Bull JH, Ellison G, Patel A, Muir G, Walker M, Underwood M, et al., 'Identification of potential diagnostic markers of prostate cancer and prostatic intraepithelial neoplasia using cDNA microarray', British Journal of Cancer, 84 1512-1519 (2001) [C1]
DOI 10.1054/bjoc.2001.1816
2001 Morris-Jones R, Walker M, Staughton RCD, Sheridan DJ, Rajappan K, Leonard J, Hardman C, 'Lichen myxoedematosus with associated cardiac abnormalities.', British Journal of Dermatology, 144 594-596 (2001) [C1]
DOI 10.1046/j.1365-2133.2001.04091.x
2001 Dave U, Loh V, Teare J, Thursz MR, Walker MM, 'Active inflammation and intestinal metaplasia at the cardia are not related to GORD', GASTROENTEROLOGY, 120 A424-A424 (2001)
2001 Dave U, Mahadeva U, Loh V, Hills K, Thursz MR, Walker MM, 'Peri Z-line biopsy during routine upper GI enddoscopy: From where and how many?', GASTROENTEROLOGY, 120 A428-A428 (2001)
2001 Crabtree JE, Court M, Walker MM, Coulson PS, Coggle S, Robinson PA, et al., 'The effects of chronic schistosomiasis on murine Helicobacter induced gastritis', GASTROENTEROLOGY, 120 A707-A707 (2001)
2001 Sutton P, Danon SJ, Walker M, Thompson LJ, Wilson J, Kosaka T, Lee A, 'Post-immunisation gastritis and helicobacter infection in the mouse: A long term study', Gut, 49 467-473 (2001) [C1]
DOI 10.1136/gut.49.4.467
2001 Thilagarajah R, Witherow RO, Walker M, 'Oral cimetidine gives effective symptom relief in painful bladder disease: A prospective, randomized, double-blind placebo-controlled trial', BJU International, 87 207-212 (2001) [C1]
DOI 10.1046/j.1464-410X.2001.02031.x
Citations Web of Science - 49
2001 Walker M, 'Gastric mucosal immune response in Helicobacter pylori infection in children - Men are not mice and more paediatric studies are needed', Digestive and Liver Disease, 33 7-9 (2001) [C1]
2000 Morris-Jones R, Walker M, Hardman C, 'Multicentric reticulohistiocytosis associated with Sjogren's syndrome', British Journal of Dermatology, 143 649-650 (2000) [C1]
DOI 10.1046/j.1365-2133.2000.03730.x
2000 Walker MM, Teare JP, Negus R, Rice AJ, Loh V, 'Are all five biopsy sites of the updated Sydney system essential to assess gastritis?', GASTROENTEROLOGY, 118 A1320-A1320 (2000)
2000 Marshall JK, Irvine EJ, 'Increased intestinal permeability precedes Crohn's disease (CD) in a subject with familial risk.', GASTROENTEROLOGY, 118 A1356-A1356 (2000)
2000 Marshall JC, Karim NQ, Worku M, Morgan MY, Walker MM, 'Motility and survival of Helicobacter pylori in alcoholic beverages.', GASTROENTEROLOGY, 118 A1356-A1356 (2000)
2000 Griffiths AE, Walker MM, Loh V, Thursz MR, 'Polymorphisms in IL-1 beta and IL-1 receptor antagonist genes increase the risk of gastric atrophy and intestinal metaplasia in patients infected with Helicobacter pylori.', GUT, 47 A53-A54 (2000)
2000 Walker MM, Negus R, Rice AJ, Loh V, Teare J, Thursz MR, 'Are all five sites of the Sydney system essential to assess H-pylori and gastritis?', GUT, 47 A57-A57 (2000)
2000 Walker MM, Worku ML, Karim QN, Thursz MR, 'Mice are not men: The Sydney system does not discriminate the genetically determined degree of gastritis in H-felis infection.', GUT, 47 A62-A62 (2000)
1999 Karim QN, Thursz MR, Murray E, Eggleton P, Reid KB, Worku M, Walker MM, 'Kinetic impairment of Helicobacter pylori by the collectin surfactant protein D.', GASTROENTEROLOGY, 116 A745-A745 (1999)
1999 Marshall JC, Morgan MY, Walker MM, 'Upper GI pathology in relation to Helicobacter pylori (Hp) status in alcohol abusers', GUT, 44 A118-A118 (1999)
1999 Marshall JC, Karim QN, Worku ML, Morgan MY, Walker MM, 'Motility and survival of Helicobacter pylori in alcoholic beverages', GUT, 45 A15-A15 (1999)
1999 Walker MM, Karim QN, Worku M, Murray E, Eggleton P, Reid KBM, Thursz MR, 'Direct observation of kinetics and agglutination of Helicobacter pylori with the collectin, surfactant protein D', GUT, 45 A41-A42 (1999)
1999 Walker M, 'HTLV-I infection and the low prevalence of Helicobacter pylori infection in Japan', European Journal of Gastroenterology and Hepatology, 11 481-483 (1999) [C1]
1999 Worku ML, Sidebotham RL, Walker M, Keshavarz T, Karim QN, 'The relationship between Helicobacter pylori motility, morphology and phase of growth: Implications for gastric colonization and pathology', Microbiology, 145 2803-2811 (1999) [C1]
Citations Web of Science - 25
1998 Gummett P, Walker MM, Loh V, Thomas HJW, Teare JP, Thursz MR, 'Advantages of near patient testing for H-pylori using infrared isotope analysis.', GASTROENTEROLOGY, 114 A141-A141 (1998)
DOI 10.1016/S0016-5085(98)80575-1
1998 MacDonald S, Thursz MR, Eggleton P, Reid KBM, Walker MM, 'Surfactant protein D expression in normal and H-pylori-infected human gastric antral mucosa.', GASTROENTEROLOGY, 114 A1028-A1029 (1998)
DOI 10.1016/S0016-5085(98)84186-3
1998 Walker MM, Macdonald S, Thursz MR, Eggleton P, Reid KBM, 'Surfactant protein D expression in normal and H-pylori infected human gastric antral mucosa', GUT, 42 A77-A77 (1998)
1998 Gummett P, Walker MM, Loh V, Thomas HJW, Teare JP, Thursz MR, 'Advantages of near patient testing for H-pylori using infra-red isotope analysis', GUT, 42 A81-A81 (1998)
1998 Walker MM, Thursz MR, Karim QN, MacDonald S, Murray E, Eggleton P, Reid KBM, 'The role of the collectin surfactant protein D in Helicobacter pylori infection', GUT, 43 A16-A16 (1998)
1998 Griffiths AE, Walker MM, Thursz MR, 'Allele 2 of the IL-1 receptor antagonist gene predisposes to chronic H-pylori infection', GUT, 43 A26-A26 (1998)
1998 Griffiths AE, Walker MM, Thursz MR, 'Influence of polymorphisms in the IL-10 and TNFa promoter regions on the outcome of H-pylori infection', GUT, 43 A31-A31 (1998)
1998 Thilagarajah R, Witherow RO, Walker M, 'Quantitative histopathology can aid diagnosis in painful bladder syndrome', Journal of Clinical Pathology, 51 211-214 (1998) [C1]
Citations Web of Science - 6
1998 Walker M, Crabtree JE, 'Helicobacter pylori infection and the pathogenesis of duodenal ulceration', Annals of the New York Academy of Sciences, 859 96-111 (1998) [C1]
DOI 10.1111/j.1749-6632.1998.tb11114.x
Citations Web of Science - 41
1998 Sidebotham RL, Dhir NK, Elder JB, Spencer J, Walker MM, Schrager J, 'Changes to mucins in uninvolved mucosa and at the tumour site in gastric adenocarcinoma of intestinal type (vol 94, pg 87, 1998)', CLINICAL SCIENCE, 94 333-333 (1998)
1998 Sidebotham RL, Dhir NK, Elder JB, Spencer J, Walker M, Schrager J, 'Changes to mucins in uninvolved mucosa and at the tumour site in gastric adenocarcinoma of intestinal type', Clinical Science, 94 87-99 (1998) [C1]
Citations Web of Science - 2
1997 Thilagarajah R, Vale JA, Witherow RO, Walker M, 'A clinicopathological approach to cystitis -recommendations for simplified pathology reporting', British Journal of Urology (BJU) International, 79 567-571 (1997) [C1]
Citations Scopus - 5Web of Science - 5
1997 Griffiths AE, Thursz MR, Walker MM, 'Do intestinal metaplasia and gastric atrophy reverse after H-pylori eradication?', GASTROENTEROLOGY, 112 A134-A134 (1997)
1997 Walker MM, Sarraf CE, Griffiths AE, Thursz M, Calam J, 'Ultrastructure of neuroendocrine cells in the duodenum of Helicobacter pylori positive patients with duodenal ulcer.', GASTROENTEROLOGY, 112 A324-A324 (1997)
1997 Gibbons AH, Legon S, Walker M, Ghatei M, Calem J, 'The effect of gastrin-releasing peptide on gastrin and somatostatin messenger RNAs in humans infected with Helicobacter pylori', Gastroenterology, 112 1940-1947 (1997) [C1]
DOI 10.1053/gast.1997.v112.pm9178686
Citations Web of Science - 26
1997 Griffiths AE, Thursz MR, Pryce D, Walker MM, 'Reflux symptoms in the long term follow up of patients after Helicobacter pylori eradication', GUT, 40 W10-W10 (1997)
1997 Griffiths AE, Thursz MR, Walker MM, 'Do intestinal metaplasia and gastric atrophy reverse after H-pylori eradication?', GUT, 41 A48-A49 (1997)
Citations Web of Science - 10
1997 Sullivan J, Thursz MR, Griffiths AE, Walker MM, 'E-cadherin expression in precursor lesions of gastric carcinoma', GUT, 41 A28-A28 (1997)
1997 Griffiths AE, Walker MM, Mantafounis D, Thursz MR, 'The -308 polymorphism in the TNF alpha gene is not associated with increased risk of duodenal ulcer', GUT, 41 A171-A171 (1997)
1997 Hardman CM, Garioch JJ, Leonard JJ, Thomas HJW, Walker M, Lortan JE, et al., 'Absence of Toxicity of Oats in Patients with Dermatitis Herpetiformis', New England Journal of Medicine, 337 1884-1887 (1997) [C1]
DOI 10.1056/NEJM199712253372604
1997 Griffiths AE, Walker M, 'Helicobacter pylori and its role in peptic ulcer disease', Nutrition and Food Science, 97 141-145 (1997) [C1]
DOI 10.1108/00346659710179679
1997 Walker M, Baron JH, 'Hunterian peptic ulcers and Helicobacter pylori.', Annals of the Royal College of Surgeons of England, 79 368-371 (1997) [C1]
Citations Scopus - 2Web of Science - 2
1996 Gibbons AH, Jordinson M, Legon S, Walker MM, Calam J, 'Somatostatin mRNA expression is reduced in inflamed gastric mucosa in rats', GASTROENTEROLOGY, 110 A116-A116 (1996)
1996 Pryce DI, Harris AW, Gabe SM, Karim QN, Beveridge I, Langworthy H, et al., 'One week of lansoprazole, clarithromycin and metronidazole eradicates Helicobacter pylori', GASTROENTEROLOGY, 110 A235-A235 (1996)
Citations Web of Science - 12
1996 Walker MM, Harris AW, LeRoux PH, Baron JH, Misiewicz JJ, 'D cells in the antrum are decreased in Helicobacter pylori positive patients with duodenal ulcer due to active inflammation in the foveolar pits.', GASTROENTEROLOGY, 110 A290-A290 (1996)
Citations Web of Science - 1
1996 Harris AW, Gummett PA, Walker M, Misiewicz JJ, Baron JH, 'Relation between gastric acid output, Helicobacter pylori, and gastric metaplasia in the duodenal bulb', Gut, 39 513-520 (1996) [C1]
Citations Web of Science - 54
1996 Birch HA, Glass JM, Vale J, Walker M, 'Myxoid renal cell carcinoma: Histological, immunocytochemical and ultrastructural study', Journal of Clinical Pathology, 49 1015-1017 (1996) [C1]
Citations Web of Science - 2
1996 Harris AW, Walker M, Smolka A, Waller JM, Baron JH, Misiewicz JJ, 'Parietal cells in the duodenal bulb and their relation to Helicobacter pylori infection', Journal of Clinical Pathology, 49 309-312 (1996) [C1]
Citations Web of Science - 2
1996 Walker M, Pretolani S, Gasbarrini G, 'Gastric carcinoma and gastric lymphoma', Current Opinion in Gastroenterology, 12 33-36 (1996) [C1]
Citations Web of Science - 11
1996 Harris AW, Pryce DI, Gabe SM, Karim QN, Walker M, Langworthy H, et al., 'Lansoprazole, clarithromycin and metronidazole for seven days in Helicobacter pylori infection', Alimentary Pharmacology and Therapeutics, 10 1005-1008 (1996) [C1]
Citations Web of Science - 46
1996 Sarker SK, Mendiola R, Spigelman A, Walker M, Coleman D, 'DNA ploidy on cytologic and tissue sections of breast lumps: A comparison using image analysis', Analytical and Quantitative Cytology and Histology, 18 19-22 (1996) [C1]
1995 Baker BS, Garioch JJ, Bokth S, Thomas H, Walker M, Leonard JN, Fry L, 'Lack of proliferative response by gluten-specific T cells in the blood and gut of patients with Dermatitis Herpetiformis', Journal of Autoimmunity, 8 561-574 (1995) [C1]
Citations Web of Science - 5
1995 Birley HDL, Luzzi GA, Taylor-Robinson D, Walker M, Renton AM, 'Retinoic acid derivatives and HPV infection', International Journal of STD and AIDS, 6 368-368 (1995) [C1]
1995 Brace W, Bain B, Walker M, Catovsky D, 'Teaching cases from the Royal Marsden Hospital. Case 9: An elderly patient with unusual circulating cells', Leukemia and Lymphoma, 18 529-530 (1995) [C1]
1995 HARRIS AW, WALKER MM, WALLER JM, BARON JH, MISIEWICZ JJ, 'GASTRIC METAPLASM IN THE DUODENAL BULB BEFORE AND 6 MONTHS AFTER ERADICATION OF HELICOBACTER-PYLORI', GASTROENTEROLOGY, 108 A108-A108 (1995)
DOI 10.1016/0016-5085(95)23097-1
Citations Web of Science - 2
1995 LEROUX PH, HARRIS AW, WALKER MM, MISIEWICZ JJ, BARON JH, 'GASTRIC-ACID OUTPUT, BACTERIAL LOAD AND GASTRITIS IN HELICOBACTER-PYLORI POSITIVE PATIENTS WITH DUODENAL-ULCER', GASTROENTEROLOGY, 108 A147-A147 (1995)
DOI 10.1016/0016-5085(95)23251-6
Citations Web of Science - 1
1995 Logan RPH, Walker M, Misiewicz JJ, Gummett PA, Karim QN, Baron JH, 'Changes in the intragastric distribution of Helicobacter pylori during treatment with omeprazole', Gut, 36 12-16 (1995) [C1]
Citations Web of Science - 328
1995 Purohit A, Ghilchik MW, Duncan L, Wang DY, Singh A, Walker M, Reed MJ, 'Aromatase activity and interleukin-6 production by normal and malignant breast tissues', Journal of Clinical Endocrinology and Metabolism, 80 3052-3058 (1995) [C1]
Citations Web of Science - 145
1995 Walker M, Smolka A, Waller JM, Evans DJ, 'Identification of parietal cells in gastric body mucosa with HMFG-2 monoclonal antibody', Journal of Clinical Pathology, 48 832-834 (1995) [C1]
Citations Web of Science - 10
1994 Logan RPH, Gummett PA, Schaufelberger HD, Greaves RRFH, Mendelson GM, Walker M, et al., 'Eradication of Helicobacter pylori with clarithromycin and omeprazole', Gut, 35 323-326 (1994) [C1]
Citations Web of Science - 205
1994 Logan RHP, Gummett PA, Misiewicz JJ, Karim QN, Walker M, Baron JH, 'One week's anti-Helicobacter pylori treatment for duodenal ulcer', Gut, 35 15-18 (1994) [C1]
Citations Web of Science - 47
1994 Birley HDL, Luzzi GA, Walker M, Ryait B, Taylor-Robinson D, Renton AM, 'The association of human papillomavirus infection with balanoposthitis: A description of five cases with proposals for treatment', International Journal of STD and AIDS, 5 139-141 (1994) [C1]
Citations Web of Science - 4
1993 Walker M, Lessing MPA, 'Fatal pulmonary infection due to Mycobacterium fortuitum', Journal of Clinical Pathology, 46 271-272 (1993) [C1]
Citations Web of Science - 12
1993 Walker M, Duffy T, 'Relative friendly death certificates.', Journal of Clinical Pathology, 46 782-783 (1993) [C3]
DOI 10.1136/jcp.46.8.782-c
Citations Web of Science - 1
1993 Coldham NG, Lai LC, Ghilchik MW, Walker M, James VHT, Reed MJ, 'The effect of treatment with 4-hydroxyandrostenedione or medroxyprogesterone acetate on human breast tumour regression', Anticancer Research: international journal of cancer research and treatment, 13 753-758 (1993) [C1]
Citations Web of Science - 3
1993 LOGAN RPH, GUMMETT PA, MISIEWICZ JJ, KARIM QN, WALKER MM, BARON JH, '2-WEEK ERADICATION REGIMEN FOR METRONIDAZOLE-RESISTANT HELICOBACTER-PYLORI', ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 7 149-153 (1993)
Citations Web of Science - 21
1993 Logan RPH, Gummett PA, Misiewicz JJ, Karim QN, Walker M, Baron JH, 'Two-week eradication regimen for metronidazole-resistant helicobacter pylori', Alimentary Pharmacology and Therapeutics, 7 149-153 (1993) [C1]
1993 Walker M, Logan RPH, Gummett PA, Baron JH, Misiewicz JJ, 'The influence of Helicobacter pylori eradication on the structure of duodenal ulcer scars', European Journal of Gastroenterology and Hepatology, 56 S97-S98 (1993) [C1]
Citations Web of Science - 5
1993 Hillman RJ, Ryait BK, Botcherby M, Walker M, Taylor-Robinson D, 'Human papillomavirus DNA in the urogenital tracts of men with genital dermatoses: Evidence for multifocal infection', International Journal of STD and AIDS, 4 147-154 (1993) [C1]
Citations Web of Science - 10
1993 Birley HDL, Walker M, Luzzi GA, Bell R, Taylor-Robinson D, Byrne M, Renton AM, 'Clinical features and management of current balanitis; association with atopy and genital washing', Sexually Transmitted Infections, 69 400-403 (1993) [C1]
Citations Web of Science - 36
1992 Baker BS, Brent L, Valdimarsson H, Powles AV, Al-Imara L, Walker M, Fry L, 'Is epidermal cell proliferation in psoriatic skin grafts on nude mice driven by T-cell derived cytokines?', British Journal of Dermatology, 126 105-110 (1992) [C1]
DOI 10.1111/j.1365-2133.1992.tb07805.x
1992 Logan RPH, Hurlimann S, Gummett PA, Walker M, Karim ON, Baron JH, Misiewicz JJ, 'How quickly does Helicobacter pylori (H. pylori) recur after treatment?', Gut, 33 S3-S3 (1992) [C1]
DOI 10.1136/gut.33.1_Suppl.S3
1992 Logan RPH, Gummett PA, Hegarty BT, Walker M, Baron JH, Misiewicz JJ, 'Clarithromycin and omeprazole for Helicobacter pylori', Lancet, 340 239-239 (1992) [C3]
DOI 10.1016/0140-6736(92)90502-T
Citations Web of Science - 99
1992 HILLMAN RJ, WALKER MM, HARRIS JRW, TAYLORROBINSON D, 'PENILE DERMATOSES - A CLINICAL AND HISTOPATHOLOGICAL STUDY', GENITOURINARY MEDICINE, 68 166-169 (1992)
Citations Web of Science - 26
1992 Hillman RJ, Waldron S, Walker M, Harris JRW, 'Granuloma annulare of the penis', Sexually Transmitted Infections, 68 47-49 (1992) [C1]
Citations Web of Science - 14
1991 Logan RPH, Polson RJ, Misiewicz JJ, Rao G, Karim NQ, Newell D, et al., 'Simplified single sample 13Carbon urea breath test for Helicobacter pylori: Comparison with histology, culture, and ELISA serology', Gut, 32 1461-1464 (1991) [C1]
Citations Web of Science - 190
1991 Logan RPH, Gummett PA, Misiewicz JJ, Karim QN, Walker M, Baron JH, 'One week eradication regimen for Helicobacter pylori', Lancet, 338 1249-1252 (1991) [C1]
DOI 10.1016/0140-6736(91)92111-E
Citations Web of Science - 171
1991 Watson JAS, Walker M, Smith NP, Hunt DM, 'Malignant chondroid syringoma - A rare cause of secondary bone tumour', Clinical and Experimental Dermatology, 16 306-307 (1991) [C1]
Citations Web of Science - 17
1991 Logan RPH, Dill S, Bauer FE, Walker M, Hirschl AM, Gummett PA, et al., 'The European 13C-urea breath test for the detection of Helicobacter pylori', European Journal of Gastroenterology and Hepatology, 3 915-921 (1991) [C1]
Citations Web of Science - 244
1991 Hillman RJ, Harris JRW, Walker M, 'Value of performing biopsies in genitourinary clinics', Sexually Transmitted Infections, 67 73-73 (1991) [C3]
1990 Baron JH, Karim QN, Walker M, 'H pylori and duodenal ulcer', Gut, 31 242-243 (1990) [C3]
1990 Walker M, Karim QN, Payne A, Baron JH, 'Distribution of Campylobacter pylori in the upper and lower gastrointestinal tract: a microbiological and histological study', Journal of Clinical Pathology, 43 82-82 (1990) [C3]
1990 Francis ND, Logan RPH, Walker M, Polson RJ, Boylston AW, Pinching AJ, et al., 'Campylobacter pylori in the upper gastrointestinal tract of patients with HIV-1 infection', Journal of Clinical Pathology, 43 60-62 (1990) [C1]
Citations Web of Science - 31
1990 Logan RPH, Polson RJ, Baron JH, Walker M, 'New spiral bacterium in the gastric mucosa: Gastrospirillum hominis', Journal of Clinical Pathology, 43 262-262 (1990) [C3]
Citations Web of Science - 7
1990 Logan RPH, Polson RJ, Rao G, Walker M, Pedley S, Harris JRW, et al., 'Helicobacter pylori and HIV infection', Lancet, 335 1456-1456 (1990) [C3]
Citations Web of Science - 10
1990 Doble A, Walker M, Harris JRW, Taylor-Robinson D, Witherow OR, 'Intraprostatic antibody deposition in chronic abacterial prostatitis', British Journal of Urology (BJU) International, 65 598-605 (1990) [C1]
Citations Web of Science - 43
1990 Holder P, Plail R, Walker M, Witherow OR, 'Cystitis glandularis - Reversal with intravesical steroid therapy', British Journal of Urology (BJU) International, 65 547-548 (1990) [C1]
Citations Web of Science - 3
1989 McFadden JP, Powles AV, Walker M, 'Rosacea induced by PUVA therapy', British Journal of Dermatology, 121 413-413 (1989) [C3]
DOI 10.1111/j.1365-2133.1989.tb01440.x
1989 Logan RPH, Walker M, Francis ND, Kitchen V, Polson RJ, Pinching AJ, Baron JH, 'Campylobacter pylori in acquired immunodeficiency syndrome', Gastroenterology, 96 1229-1229 (1989) [C3]
1989 Doble A, Thomas BJ, Walker M, Harris JRW, Witherow OR, Taylor-Robinson D, 'The role of Chlamydia trachomatis in chronic abacterial prostatitis: A study using ultrasound guided biopsy', Journal of Urology, 141 332-333 (1989) [C1]
Citations Web of Science - 65
1989 Logan RPH, Karim QN, Polson RJ, Walker M, Baron JH, Lord MG, et al., 'Gastrospirillum hominis infections of the stomach', Lancet, 2 672-672 (1989) [C1]
DOI 10.1016/S0140-6736(89)90909-4
Citations Web of Science - 5
1989 Coelho LGV, Payne A, Karim QN, Baron JH, Walker M, 'Campylobacter pylori in esophagus antrum, and duodenum. A histological and microbiological study', Digestive Diseases and Sciences, 34 445-448 (1989) [C1]
Citations Web of Science - 25
1989 Byrne MA, Walker M, Leonard J, Pryce D, Taylor-Robinson D, 'Recognising covert disease in women with chronic vulval symptoms attending an STD clinic: Value of detailed examination including colposcopy', Sexually Transmitted Infections, 65 46-49 (1989) [C1]
Citations Web of Science - 13
1989 Witherow OR, Gillespie L, McMullen L, Goldin RD, Walker M, 'Painful bladder syndrome - A clinical and immunopathological study', British Journal of Urology (BJU) International, 64 158-161 (1989) [C1]
Citations Web of Science - 13
1989 Doble A, Thomas BJ, Furr PM, Walker M, Harris JRW, Witherow OR, Taylor-Robinson D, 'A search for infectious agents in chronic abacterial prostatitis using ultrasound guided biopsy', British Journal of Urology (BJU) International, 64 297-301 (1989) [C1]
Citations Web of Science - 32
1988 Shaikh NA, Beaconsfield T, Walker M, Ghilchik MW, 'Postirradiation angiosarcoma of the breast - A case report', European Journal of Surgical Oncology, 14 449-451 (1988) [C1]
1987 Coelho LG, Das SS, Karim QN, Walker M, Queiroz DM, Mendes EN, et al., 'Campylobacter pyloridis in the upper gastrointestinal tract: a Brazilian study.', Arquivos de Gastroenterologia, 24 5-9 (1987) [C1]
1987 Forbat LN, Walker M, Gribble RJ, Baron JH, 'Lack of clinical value of biopsy of duodenal ulcer at endoscopy.', Gastrointestinal Endoscopy, 33 269-270 (1987) [C3]
1987 McMullen L, Walker M, Bain LA, Karim QN, Baron JH, 'Histological identification of Campylobacter using Gimenez technique in gastric antral mucosa', Journal of Clinical Pathology, 40 464-465 (1987) [C1]
Citations Web of Science - 43
1987 Lambrianides AL, Walker M, Rosin RD, 'Primary retroperitoneal teratoma in adults', Urology, 29 310-312 (1987) [C1]
Citations Web of Science - 16
1986 GRIFFITHS CEM, LEONARD JN, WALKER MM, 'ACQUIRED ICHTHYOSIS AND SARCOIDOSIS', CLINICAL AND EXPERIMENTAL DERMATOLOGY, 11 296-298 (1986)
DOI 10.1111/j.1365-2230.1986.tb00463.x
Citations Web of Science - 9
Show 188 more journal articles

Review (11 outputs)

Year Citation Altmetrics Link
2011 Webster P, Wujanto L, Fisher C, Walker M, Ramakrishnan R, Naresh K, et al., 'Malignancies confined to disused arteriovenous fistulae in renal transplant patients: An important differential diagnosis', American Journal of Nephrology (2011) [D1]
DOI 10.1159/000328908
Citations Scopus - 6Web of Science - 6
2011 Walker M, Marray JA, 'An update in the diagnosis of coeliac disease', Histopathology (2011) [D1]
DOI 10.1111/j.1365-2559.2010.03680.x
Citations Scopus - 28Web of Science - 31
2011 Walker M, Talley NJ, 'Clinical value of duodenal biopsies - Beyond the diagnosis of coeliac disease', Pathology Research and Practice (2011) [D1]
DOI 10.1016/j.prp.2011.08.00
2010 Powell N, Walker M, Talley NJ, 'Gastrointestinal eosinophils in health, disease and functional disorders', Nature Reviews Gastroenterology and Hepatology (2010) [D1]
DOI 10.1038/nrgastro.2010.5
Citations Scopus - 33Web of Science - 27
Co-authors Nicholas Talley
2010 Goddard AF, Badreldin R, Pritchard DM, Walker M, Warren B, 'The management of gastric polyps', Gut (2010) [D1]
DOI 10.1136/gut.2009.182089
Citations Scopus - 42Web of Science - 30
2008 Walker M, Talley NJ, 'Functional Gastrointestinal Disorders and the Potential Role of Eosinophils', Gastroenterology Clinics of North America (2008) [D1]
DOI 10.1016/j.gtc.2008.02.007
Citations Scopus - 15Web of Science - 11
Co-authors Nicholas Talley
2003 Walker M, 'Is intestinal metaplasia of the stomach reversible?', Gut (2003) [D1]
DOI 10.1136/gut.52.1.1
Citations Scopus - 38Web of Science - 32
2003 Walker M, Whittle BJR, 'British Journal of Clinical Pharmacology review series Clinical research methods in gastroenterology', British Journal of Clinical Pharmacology (2003) [D1]
DOI 10.1046/j.1365-2125.2003.01940.x
Citations Scopus - 1
2003 Walker M, 'Biopsy assessment of drug efficacy in the gastrointestinal tract.', British Journal of Clinical Pharmacology (2003) [D1]
DOI 10.1046/j.1365-2125.2003.01981.x
2001 Logan RPH, Walker M, 'ABC of the upper gastrointestinal tract: epidemiology and diagnosis of Helicobacter pylori infection.', British Medical Journal (2001) [D1]
Citations Scopus - 118Web of Science - 79
1987 Walker M, Griffiths CEM, Weber J, Leonard JN, Forster JM, Powles AV, et al., 'Dermatological conditions in HIV infection', British Medical Journal (1987) [D1]
Citations Web of Science - 9
Show 8 more reviews

Conference (37 outputs)

Year Citation Altmetrics Link
2014 Shah A, Talley NJ, Walker M, Koloski N, Shanahan ER, Morrison M, et al., 'Is geographic variability of incidence and prevalence of Crohn's Disease linked to Helicobacter pylori? An ecologic study', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2014) [E3]
Co-authors Nicholas Talley
2014 Zala A, Bollipo S, Walker MM, Talley NJ, 'Endoscopic and histologic findings in food bolus obstruction: Not all eosinophilic esophagitis', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2014) [E3]
Co-authors Nicholas Talley
2014 Faulkner S, Roselli S, Thorne RF, Scarlett CJ, Walker MM, Hondermarck H, 'PRONGF AND SORTILIN EXPRESSION AND FUNCTION IN PANCREATIC CANCER', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2014) [E3]
Co-authors Hubert Hondermarck, Rick Thorne, C Scarlett
2013 Patel N, Blackwell VJ, Patel P, Walker MM, Williams HR, 'THE DIAGNOSTIC UTILITY OF ENDOSCOPIC DUODENAL BIOPSIES FOR GASTROINTESTINAL INVESTIGATION', GUT, Glasgow, SCOTLAND (2013) [E3]
DOI 10.1136/gutjnl-2013-304907.670
2012 Aggarwal KR, Walker MM, Shim L, Powell N, Bassan MS, Kalantar JS, et al., 'Duodenal Eosinophilia and Early Satiety in Functional Dyspepsia (FD): Confirmation of a Positive Biomarker Association for FD in an Australian Cohort', GASTROENTEROLOGY, San Diego, CA (2012) [E3]
Citations Web of Science - 1
Co-authors Nicholas Talley
2012 Rakhra GS, Villagran A, Harris PR, Walker MM, Crabtree JE, 'Increased Duodenal Intra Epithelial Lymphocytes (IELs) are Associated With Recurrent Abdominal Pain and Parasite Infection but Not Helicobacter pylori in a Paediatric Chilean Cohort', GASTROENTEROLOGY, San Diego, CA (2012) [E3]
Citations Web of Science - 1
2012 Powell N, Walker MM, Talley NJ, Ronkainen J, Aro P, Storskrubb T, et al., 'Smoking is associated with disordered homeostasis of small intestinal and proximal colonic mucosal mast cells', Gastroenterology: 2012 DDW Abstract Supplement, San Diego, CA (2012) [E3]
Co-authors Nicholas Talley
2012 Walker MM, Rakhra GS, Villagran A, Harri PR, Crabtree JE, 'INCREASED DUODENAL INTRA EPITHELIAL LYMPHOCYTES (IELS) ARE ASSOCIATED WITH RECURRENT ABDOMINAL PAIN AND PARASITE INFECTION BUT NOT HELICOBACTER PYLORI IN A PAEDIATRIC CHILEAN COHORT', GUT (2012) [E3]
DOI 10.1136/gutjnl-2012-302514c.132
2012 Nayagam S, Lloyd K, Byrne E, Walker MM, Williams HRT, 'INVESTIGATIONS FOR COELIAC DISEASE IN IRON DEFICIENCY ANAEMIA-ARE WE FOLLOWING BSG GUIDELINES?', GUT (2012) [E3]
DOI 10.1136/gutjnl-2012-302514d.183
2012 Walker MM, Aggarwal KR, Shim L, Powell N, Bassan M, Kalantar JS, et al., 'Duodenal eosinophilia and early satiety in functional dyspepsia (FD): Confirmation of a positive biomarker association for FD in an Australian cohort', Gut, Liverpool, UK (2012) [E3]
Co-authors Nicholas Talley
2011 Maisnam D, Walker MM, Seneviratne S, 'Audit of Duodenal Biopsy Subsequent to Positive Coeliac Serology, and Reaudit of Coeliac Serology Testing after Histopathological Diagnosis of Lymphocytic Duodenosis', JOURNAL OF PATHOLOGY, Univ Cambridge, Dept Pathol, Cambridge, ENGLAND (2011) [E3]
2011 Queiroz DMM, Harris P, Sanderson I, Rocha AMC, Rocha GA, Villagran A, et al., 'IRON DEFICIENCY ANAEMIA (IDA) AND H. PYLORI INFECTION IN CHILDREN: A MULTICENTERED STUDY', HELICOBACTER, Dublin, IRELAND (2011) [E3]
2010 Duval C, Bransfield K, Walker MM, Varro A, Robinson PA, Crabtree JE, 'LONG-TERM INFECTION OF HELICOBACTER PYLORI 48GX, AND OUTPUT STRAINS 12.2 AND 12.3, RESULTS IN HYPERGASTRINAEMIA, GASTRIC CARCINOIDS AND DYSPLASIA IN MONGOLIAN GERBILS', GUT, Liverpool, ENGLAND (2010) [E3]
DOI 10.1136/gut.2009.208983f
2010 Walker MM, Warwick A, Ung C, Talley NJ, Kjelstrom L, Nyhlin H, et al., 'THE POPCOL STUDY: EPIDEMIOLOGY BY ENDOSCOPY IN A SWEDISH ADULT RANDOM POPULATION. INTRAEPITHELIAL LYMPHOCYTE AND EOSINOPHIL COUNTS IN THE NORMAL COLON AND IRRITABLE BOWEL SYNDROME', GUT, Liverpool, ENGLAND (2010) [E3]
DOI 10.1136/gut.2009.209049i
Co-authors Nicholas Talley
2009 Chopra S, Mayer K, Havranek E, Walker MM, Patel A, 'Does presence of Perineural invasion at biopsy correlate to upgrading of Gleason score/stage of radical prostatectomy specimens?', BJU INTERNATIONAL, Gold Coast, AUSTRALIA (2009) [E3]
2009 Sandhu DK, Foxx-Orenstein AE, Jensen KL, Smyrk TC, Zinsmeister AR, Walker MM, Talley NJ, 'Serotonin, Eosinophils and Mast Cells in Functional Bowel Disorders: Regional Differences in the Gastrointestinal Tract', GASTROENTEROLOGY, Chicago, IL (2009) [E3]
Co-authors Nicholas Talley
2009 Walker MM, Salehian SS, Murray CE, Hoare JM, Negus R, Powell N, Talley NJ, 'IMPLICATIONS OF EOSINOPHILS IN DUODENAL BIOPSIES: AN ASSOCIATION WITH ATOPY, ALLERGY, MEDICATION AND EARLY SATIETY', GUT, Glasgow, SCOTLAND (2009) [E3]
Co-authors Nicholas Talley
2008 Kogianni G, Walker MM, Waxman J, Sturge J, 'Endo180 expression by tumour cells with an invasive phenotype correlates with prostate cancer progression', EJC SUPPLEMENTS, Lyon, FRANCE (2008) [E3]
DOI 10.1016/S1359-6349(08)71480-0
2008 Rahim MN, Hoare JM, Walker MM, Negus R, Macnaughtan J, 'Lymphocytic duodenosis: Clinical presentation and investigation in a retrospective study of 55 patients', GASTROENTEROLOGY (2008) [E3]
2008 Walker MM, Murray CE, Rahim MN, Hoare JM, Negus R, Talley NJ, 'Eosinophilia is overlooked in routine duodenal biopsy practice and is linked to a history of atopy or medication', GASTROENTEROLOGY (2008) [E3]
Co-authors Nicholas Talley
2008 Walker MM, Talley NJ, Prabhakar M, Pennaneach CJ, Rorkainen J, Aro P, et al., 'Duodenal mast cell hyperplasia and nerve proximity in irritable bowel syndrome', GASTROENTEROLOGY (2008) [E3]
Co-authors Nicholas Talley
2008 Rahim M, Macnaughtan J, Hoare J, Negus R, Walker MM, 'Lymphocytic duodenosis: Clinical presentation and investigation in a retrospective study of 55 patients', GUT, Brimingham, ENGLAND (2008) [E3]
2008 Walker MM, Talley NJ, Prabhakar M, Pennaneac'h C, Aro P, Ronkainen J, et al., 'Duodenal mastocytosis in irritable bowel syndrome: An adult endoscopic population-based case-control study (Kalixanda)', GUT, Brimingham, ENGLAND (2008) [E3]
Co-authors Nicholas Talley
2008 Khamri W, Walker MM, Atherton JC, Thursz MR, Bamford KB, Lechler RI, Lombardi G, 'Helicobacter pylori stimulates dendritic cells to induce IL-17 expression from CD4(+) T lymphocytes', IMMUNOLOGY, Glasgow, SCOTLAND (2008) [E3]
2008 Kogianni G, Walker MM, Waxman J, Sturge J, 'ENDO180 EXPRESSION BY TUMOUR CELLS WITH AN INVASIVE PHENOTYPE CORRELATES WITH PROSTATE CANCER PROGRESSION', ANTICANCER RESEARCH (2008) [E3]
2007 Talley NJ, Walker MM, Aro P, Ronkainen JA, Storskrubb T, Hindley LA, et al., 'Duodenal eosinophilia and mast cell infiltration in functional dyspepsia (FD) and irritable bowel syndrome (IBS): Duodenal eosinophilia a biomarker for FD but not IBS in adults?', GASTROENTEROLOGY, Washington, DC (2007)
Citations Web of Science - 2
Co-authors Nicholas Talley
2007 Walker MM, Murray JA, Ronkainen JA, Aro P, Storskrubb T, Vieth M, et al., 'Lymphocytic duodenosis (LD) in a population based study (Kalixanda) - Sorting the wheat from the chaff', GASTROENTEROLOGY, Washington, DC (2007)
Co-authors Nicholas Talley
2006 Tran-Dang M-A, Smith RD, Khoubehi B, Patel A, Walker MM, 'Stromal nodules and vessel wall thickening in TURP specimens are associated with failure of alpha-blocker treatment', JOURNAL OF PATHOLOGY, Manchester, ENGLAND (2006)
2006 Ronkainen J, Talley NJ, Aro P, Storskrubb T, Bolling-Sternevald E, Lind T, et al., 'Prevalence of eosinophilia and eosinophilic Esophagitis in adults in the community: A random population based study (Kalixanda)', GASTROENTEROLOGY, Los Angeles, CA (2006)
Citations Web of Science - 5
Co-authors Nicholas Talley
2006 Walker MM, Goldin RD, Vieth M, Stolte M, Ronkainen J, Aro P, et al., 'A practical method for counting Intraepithelial lymphocytes in duodenal biopsies: Data from a population-based endoscopic study', GASTROENTEROLOGY, Los Angeles, CA (2006)
Co-authors Nicholas Talley
2005 Murray JA, Walker MM, Agreus L, Storskrubb T, Ronkainen J, Aro P, Talley NJ, 'Celiac disease: Defining the abnormal threshold for the intra-epithelial lymphocyte count in a random population-based endoscopic study', GASTROENTEROLOGY, Chicago, IL (2005)
Co-authors Nicholas Talley
2003 Walker MM, 'Classification of duodenitis and villous atrophy', UPDATE IN PATHOLOGY, PROCEEDINGS, Ljubljana, SLOVENIA (2003)
2003 Walker MM, Ebrahim H, Burke M, Townsend E, Thursz M, 'Columnar lined oesophagus (CLO) a tissue culture model for basement membrane manipulation', GASTROENTEROLOGY, ORLANDO, FLORIDA (2003)
DOI 10.1016/S0016-5085(03)82067-X
2002 Walker MM, Smolka AJ, Coggle S, Dubois A, 'Acute Helicobacter pylori infection and H,K-ATPase expression: Digital immunoquantitation of proton pumps in non-human primates', GUT, ATHENS, GREECE (2002)
2002 Walker MM, Crabtree J, Wang J, Coulson P, Coggle S, Robinson P, Telford J, 'The effects of chronic Schistosomiasis on murine Helicobacter gastric epithelial cell proliferation', GUT, ATHENS, GREECE (2002)
1996 Walker M, Dixon MF, 'Gastric metaplasia: Its role in duodenal ulceration', Alimentary Pharmacology and Therapeutics, Supplement, Edinburgh, UK (1996) [E2]
Citations Web of Science - 26
1993 Logan R, Poison R, Walker M, Gummett P, Baron H, Misiewicz G, 'Defining the role of Helicobacter pylori in relationship to relapse of duodenal ulcer.', Third workshop of the European Helicobacter pylori Study Group. Proceedings., Toledo, Spain (1993) [E1]
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Grants and Funding

Summary

Number of grants 2
Total funding $990,760

Click on a grant title below to expand the full details for that specific grant.


20142 grants / $990,760

Functional dyspepsia: Characterisation of the immunopathology and testing a novel therapeutic strategy.$708,146

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Laureate Professor Nick Talley, Professor Marjorie Walker, Associate Professor Michael Jones, Dr Nick Powell, Mrs Natasha Koloski, Professor Gerald Holtmann
Scheme Project Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1300107
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

High Throughput Image Capture Platform for Translational Cancer Research$282,614

Funding body: Cancer Institute NSW

Funding body Cancer Institute NSW
Project Team Conjoint Professor Stephen Ackland, Professor Rodney Scott, Professor John Forbes, Professor Xu Dong Zhang, Professor Marjorie Walker, Professor Hubert Hondermarck, Doctor Craig Gedye, Doctor Rick Thorne, Mr Loui Rassam, Doctor Stephen Braye
Scheme Research Equipment Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1400626
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y
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Research Supervision

Number of supervisions

Completed7
Current1

Total current UON EFTSL

PhD0.3

Current Supervision

Commenced Level of Study Research Title / Program / Supervisor Type
2014 PhD Functional Dyspepsia and Gastroparesis in Health and Diabetes: Characterisation of Gastrointestinal Sensorimotor Patterns and Mucosal Permeability
General Medicine, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor

Past Supervision

Year Level of Study Research Title / Program / Supervisor Type
2012 Masters Detection of Possible Intracellular Bacteria in Bladder Biopsies of Women with Overactive Bladder Symptoms
Biological Sciences, Unknown
Sole Supervisor
2011 Masters Functional Dyspepsia and the Transient Receptor Potential Vanilloid 1.
Biological Sciences, Imperial College London
Sole Supervisor
2010 Masters Allergic Immune Pathways in Functional Bowel Disease in the Lower Gastrointestinal Tract
Biological Sciences, Imperial College London
Sole Supervisor
2009 Masters Eosinophils, Mast cells, Serotonin and Neural Pathways in the Upper Gastrointestinal Tract in Functional Gastrointestinal Disorders: Functional Dyspepsia and Irritable Bowel Syndrome
Biological Sciences, Imperial College London
Sole Supervisor
2008 Masters Eosinophils, mast cells and the brain-gut axis in the duodenum of patients with non-ulcer dyspepsia
Biological Sciences, Unknown
Sole Supervisor
2003 PhD Laminins in Barrett’s oesophagus
Biological Sciences, Imperial College London
Sole Supervisor
2003 PhD The utility of free/total PSA ratios as a screening tool in the detection of prostate cancer in men aged 50-65 years
Biological Sciences, Imperial College London
Sole Supervisor
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News

PhD Scholarship - Neurogastroenterology

PhD Scholarship - Neuro-gastroenterology

August 7, 2015

A PhD scholarship is available for a student to undertake a research in Neurogastroenterology: Pathophysiological mechanisms and treatment of functional and inflammatory gastrointestinal disorders under the supervision of Laureate Professor Nick Talley and Professor Marjorie Walker.

Professor Marjorie Walker

Position

Professor of Anatomical Pathology
School of Medicine and Public Health
Faculty of Health and Medicine

Focus area

Pathology

Contact Details

Email marjorie.walker@newcastle.edu.au
Phone (02) 4921 5316
Mobile 0409 258 746

Office

Room BB107
Building Bowman Building
Location Callaghan
University Drive
Callaghan, NSW 2308
Australia
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