Staff Directory

Staff Profile

Career Summary

Biography

Professor Ashman is a NHMRC Principal Research Fellow and Gladys Brawn Professorial Fellow. She came to the University of Newcastle in 2002 from the Hanson Centre for Cancer Research and the University of Adelaide. In her career spanning 35 years she has published 150 papers in refereed international journals and conference proceedings. Career highlights include identification at the protein level of the receptor tyrosine kinase c-KIT, publication of the first monoclonal antibody to it, and the first description of c-KIT expression by haemopoietic progenitor cells in bone marrow. She has an ongoing interest in the role of mutant c-KIT in acute myeloid leukaemia and other cancers and in new drugs that target this receptor. Prof Ashman's group also identified a novel tetraspanin protein, CD151, cloned the gene, and generated the first CD151 knock-out mice. Work in this and other laboratories has shown that the CD151 protein modifies cell adhesion and migration and plays an important role in the spread (metastasis) of cancer.

Qualifications

PhD, University of Adelaide
Bachelor of Science (Honours), Flinders University

Research

Research keywords

Cell and Molecular biology of cancer

Research expertise

I was trained as a biochemist but worked for many years in immunology. In now consider myself as a cell and molecular biologist. The underlying theme of my research has always been cancer, its cellular and molecular biology and development of novel approaches to diagnosis and treatment. Major themes have been haemopoiesis and leukaemia, regulation of cellular behaviour by cell surface receptors, cellular signalling and development of novel targetted therapeutics.

Fields of Research

Code	Description	Percentage
060100	Biochemistry And Cell Biology	60
111299	Oncology And Carcinogenesis Not Elsewhere Classified	30
110199	Medical Biochemistry And Metabolomics Not Elsewhere Classified	10

Memberships

Committee/Associations (relevant to research).

Joint convenor - Hunter Medical Research Institute International Conferences on Translational Cancer Research, 2004, 2006, 2008

NHMRC Committee

Member - Grant Review Panel - Cell Biology 2005,2006
Member, 2001, 2002 - Research Fellowship Advisory Panel A

Appointments

Recipient University of Newcastle (Australia)	01/01/2006 - 01/12/2010
Fellowship National Health & Medical Research Council (Australia)	01/01/2006 - 01/12/2011

Invitations

Glivec Solid Tumour Advisory Board Novartis Pharma, United States (Conference Presentation - non published.)	2001
Summer Research Conference: tetraspanins Federation of American Societies of Experimental Biology, United States (Conference Presentation - non published.)	2004

Administrative

Administrative expertise

Initiated and coordinated B Health Sci (Hons) program in Experimental Medicine at Adelaide University,

Member, Graduate Studies Committee and Board of Research Education and Development at Adelaide University

Elected Staff Representative, Hanson Centre Executive

Member, Hanson Institute Strategic Advisory Committee

Member, NHMRC Research Fellowships Advisory Panel, 2001, 2002.

Member NHMRC Grant Review panel, 2005, 2006.

At University of Newcastle:

Member, Faculty of Health Research Management Committee (2002, 2003).

Research Portfolio Committee, 2004 (casual vacancy)

Member of multiple appointments committess and grant review panels.

Teaching

Teaching keywords

Cancer Biology

Teaching expertise

While I have always been employed in "Research Only" positions I have contributed extensively to teaching both at the University of Adelaide and the University of Newcastle. Currently I teach into the B Biomed Sci program in my areas of research expertise (Cancer biology and novel drug development).

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Publications

No publications.

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Grants and Funding

Summary

Number of grants	66
Total funding	$12,425,447

For project grants received where the lead institution is other than the University of Newcastle, details are shown in italics.

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2013 (1 grants)

Ultra-Low Temperature Cryogenic Freezer$24,596
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Jude Weidenhofer, Doctor Rick Thorne, Doctor Kathryn Skelding, Doctor Nikki Verrills, Doctor Pradeep Tanwar, Associate Professor Phillip Dickson, Doctor Murray Cairns, Professor Hubert Hondermarck, Professor Xu Dong Zhang, Associate Professor Estelle Sontag, Doctor Chen Chen Jiang, Associate Professor Liz Milward, Doctor Jean-Marie Sontag, Associate Professor Paul Tooney, Doctor Severine Roselli, Doctor Matt Dun, Doctor Chris Dayas, Doctor Lin Kooi Ong, Professor Dirk Van Helden, Mr Ben Copeland, Ms Gabrielle Briggs, Conjoint Professor Leonie Ashman, Professor John Rostas
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$24,596	2013	2013
GNo:G1201189

2012 (4 grants)

The Hunter Cancer Biobank (HCB): Maximising community value through validation, annotation and distribution throughout NSW$292,300
Funding Body: Cancer Institute NSW

Project Team
Professor John Forbes, Conjoint Professor Stephen Ackland, Professor Rodney Scott, Conjoint Associate Professor Barbara Young, Professor Hubert Hondermarck, Conjoint Professor Leonie Ashman, Professor Xu Dong Zhang, Doctor Kelly Kiejda, Doctor Nikki Verrills, Doctor Jennette Sakoff, Ms Janine Lombard, Doctor Jude Weidenhofer, Doctor Pradeep Tanwar
Scheme		Role
Infrastructure Grants		Investigator
Total Amount	Funding Start	Funding Finish
$292,300	2012	2014
GNo:G1200798

High-Resolution Isoelectric Phosphoprotein Signalling System for Signalling Research, Biomarker Validation and Drug Development – Equipment Grant$143,394
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Rick Thorne, Professor Xu Dong Zhang, Professor Hubert Hondermarck, Conjoint Professor Stephen Ackland, Doctor Lisa Lincz, Doctor Jennette Sakoff, Conjoint Professor Leonie Ashman
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$143,394	2012	2012
GNo:G1200555

Microscopic illumination system for advanced fluorescent protein technology$34,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Rick Thorne, Professor Xu Dong Zhang, Doctor Murray Cairns, Doctor Nikki Verrills, Doctor Charles De Bock, Doctor Jude Weidenhofer, Doctor Severine Roselli, Doctor Kathryn Skelding, Conjoint Professor Leonie Ashman, Professor Hubert Hondermarck
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$34,000	2012	2012
GNo:G1100983

Does Ubiquitination control the altered expression of tetraspanin proteins in Breast Cancer?$25,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Jude Weidenhofer, Conjoint Professor Leonie Ashman, Professor Hubert Hondermarck
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$25,000	2012	2012
GNo:G1200169

2011 (3 grants)

Hunter translational cancer research unit$1,693,333
Funding Body: Cancer Institute NSW

Project Team
Conjoint Professor Stephen Ackland, Conjoint Professor Leonie Ashman, Professor John Forbes, Laureate Professor Robert Sanson-Fisher, Conjoint Associate Professor Anthony Proietto, Professor Rodney Scott
Scheme		Role
Translational Cancer Research Unit		Investigator
Total Amount	Funding Start	Funding Finish
$1,693,333	2011	2014
GNo:G1100545

Identifying the mechanisms underlying altered expression and mode of action of tetraspanins CD151 and CD9 in metastasis: progression to targeted treatment for prostate cancer$375,000
Funding Body: Prostate Cancer Foundation of Australia

Project Team
Conjoint Professor Leonie Ashman, Doctor Jude Weidenhofer
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$375,000	2011	2013
GNo:G1000863

Investigation of the function of CD151 in the glomerular filtration barrier and identification of genetic modifiers of glomerular diseases$25,000
Funding Body: University of Newcastle

Project Team
Doctor Severine Roselli, Doctor Jude Weidenhofer, Conjoint Professor Leonie Ashman
Scheme		Role
Near Miss Grant		Investigator
Total Amount	Funding Start	Funding Finish
$25,000	2011	2011
GNo:G1001053

2010 (4 grants)

HMRI MRSP Infrastructure Grant (10-11) - CANCER$504,071
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Leonie Ashman, Conjoint Professor Stephen Ackland
Scheme		Role
MRSP Infrastructure Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$504,071	2010	2011
GNo:G1100269

Laser microdissection microscopy system for cell and development biology$350,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Eileen McLaughlin, Conjoint Professor Keith Jones, Laureate Professor John Aitken, Associate Professor Brett Nixon, Doctor Shaun Roman, Associate Professor Alan Brichta, Doctor Rick Thorne, Doctor Doug Smith, Associate Professor David McCurdy, Conjoint Professor Ray Rose, Professor Christopher Grof, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Doctor Brett Graham, Associate Professor Paul Tooney, Professor Roger Smith, Professor Paul Foster, Professor Trevor Day, Professor Robert Callister
Scheme		Role
Linkage Infrastructure Equipment & Facilities (LIEF)		Investigator
Total Amount	Funding Start	Funding Finish
$350,000	2010	2010
GNo:G0190369

Laser microdissection microscopy system for cell and development biology$215,000
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin, Conjoint Professor Keith Jones, Laureate Professor John Aitken, Associate Professor Brett Nixon, Doctor Shaun Roman, Associate Professor Alan Brichta, Doctor Rick Thorne, Doctor Doug Smith, Associate Professor David McCurdy, Conjoint Professor Ray Rose, Professor Christopher Grof, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Doctor Brett Graham, Associate Professor Paul Tooney, Professor Roger Smith, Professor Paul Foster, Professor Trevor Day, Professor Robert Callister
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$215,000	2010	2010
GNo:G1000874

ABI 7500 Real Time PCR System $34,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Rick Thorne, Doctor Nikki Verrills, Doctor Murray Cairns, Associate Professor Paul Tooney, Doctor Doug Smith, Professor Gordon Burns, Conjoint Professor Leonie Ashman, Conjoint Professor Keith Jones, Doctor Charles De Bock, Doctor Chris Dayas, Doctor Brett Graham, Doctor Martin Horan, Doctor Rebecca Lim, Doctor Severine Roselli, Doctor Larisa Bobrovskaya, Doctor Kathryn Skelding, Doctor Frederick Walker, Doctor Jude Weidenhofer, Associate Professor Philip Bolton, Associate Professor Alan Brichta, Professor Robert Callister, Professor Trevor Day, Associate Professor Phillip Dickson, Professor Manohar Garg, Doctor Phil Jobling, Associate Professor Derek Laver, Associate Professor Eugene Nalivaiko, Professor John Rostas
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$34,000	2010	2010
GNo:G1000055

2009 (9 grants)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000
Funding Body: ARC (Australian Research Council)

Project Team
Laureate Professor John Aitken, Professor Adam McCluskey, Doctor Mark Baker, Doctor Nikki Verrills, Professor Marcel Maeder, Doctor Xiaojing Zhou, Professor Eileen McLaughlin, Associate Professor Brett Nixon, Doctor Shaun Roman, Conjoint Professor Ray Rose, Professor Hugh Dunstan, Professor Christopher Grof, Professor Roger Smith, Conjoint Professor Peter Gibson, Conjoint Professor Alison Jones, Professor Mike Calford, Conjoint Professor Keith Jones, Doctor Rick Thorne, Emeritus Professor Peter Dunkley, Professor Paul Foster, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Associate Professor Phillip Dickson, Professor John Rostas, Professor Rodney Scott, Associate Professor Paul Tooney, Professor Phil Hansbro, Professor Pablo Moscato, Professor Paul Dastoor, Professor Peter Lewis
Scheme		Role
Linkage Infrastructure Equipment & Facilities (LIEF)		Investigator
Total Amount	Funding Start	Funding Finish
$495,000	2009	2009
GNo:G0189122

Tetraspanin proteins in prostate cancer progression and prognosis$341,000
Funding Body: Cancer Council NSW

Project Team
Conjoint Professor Leonie Ashman, Doctor Nikki Verrills, Conjoint Professor Jim Denham
Scheme		Role
Research Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$341,000	2009	2011
GNo:G0188877

MRSP Infrastructure (09-10) Cancer$283,916
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Leonie Ashman, Conjoint Professor Stephen Ackland
Scheme		Role
MRSP Infrastructure Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$283,916	2009	2010
GNo:G0900172

Confocal Laser Scanning Microscopy for Live Cell Imaging$275,000
Funding Body: ARC (Australian Research Council)

Project Team
Conjoint Professor Keith Jones, Professor Eileen McLaughlin, Laureate Professor John Aitken, Conjoint Professor Ray Rose, Emeritus Professor John Patrick, Conjoint Professor Christina Offler, Associate Professor David McCurdy, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Professor Dirk Van Helden, Doctor Nikki Verrills, Associate Professor Brett Nixon, Doctor Shaun Roman, Associate Professor Yong-Ling Ruan, Doctor Rick Thorne, Professor Mike Calford
Scheme		Role
Linkage Infrastructure Equipment & Facilities (LIEF)		Investigator
Total Amount	Funding Start	Funding Finish
$275,000	2009	2009
GNo:G0189038

IVIS Lumina II fluorescence and bioluminescence imager for in vivo analysis of tumour growth and metastasis in mouse models$153,200
Funding Body: Cancer Institute NSW

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Equipment Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$153,200	2009	2009
GNo:G0189634

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000
Funding Body: ARC (Australian Research Council)

Project Team
Laureate Professor John Aitken, Professor Adam McCluskey, Doctor Mark Baker, Doctor Nikki Verrills, Professor Marcel Maeder, Doctor Xiaojing Zhou, Professor Eileen McLaughlin, Associate Professor Brett Nixon, Doctor Shaun Roman, Conjoint Professor Ray Rose, Professor Hugh Dunstan, Professor Christopher Grof, Professor Roger Smith, Conjoint Professor Peter Gibson, Conjoint Professor Alison Jones, Professor Mike Calford, Conjoint Professor Keith Jones, Doctor Rick Thorne, Emeritus Professor Peter Dunkley, Professor Paul Foster, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Associate Professor Phillip Dickson, Professor John Rostas, Professor Rodney Scott, Associate Professor Paul Tooney, Professor Phil Hansbro, Professor Pablo Moscato, Professor Paul Dastoor, Professor Peter Lewis
Scheme		Role
Linkage Infrastructure Equipment & Facilities (LIEF) Partner funding		Investigator
Total Amount	Funding Start	Funding Finish
$50,000	2009	2009
GNo:G0189948

Study of c-KIT mutations in familial gastrointestinal stromal tumours and malignant melanoma$44,720
Funding Body: Pfizer Australia

Project Team
Mr Ricardo Vilain, Professor Rodney Scott, Conjoint Professor Leonie Ashman
Scheme		Role
Cancer Research Grant		Investigator
Total Amount	Funding Start	Funding Finish
$44,720	2009	2009
GNo:G0189919

Identification of genetic modifiers of kidney disease$25,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Severine Roselli, Conjoint Professor Leonie Ashman, Professor Rodney Scott
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$25,000	2009	2009
GNo:G0189793

3rd European Conference on Tetraspanins, Paris, 10-11 September 2009$1,175
Funding Body: University of Newcastle

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$1,175	2009	2010
GNo:G0900245

2008 (4 grants)

HMRI Cancer Research Program - MRSP Infrastructure$1,031,290
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Stephen Ackland, Conjoint Professor Leonie Ashman, Professor John Forbes, Conjoint Professor Jim Denham, Conjoint Professor Peter Hersey, Professor Gordon Burns, Professor Adam McCluskey, Doctor Nikki Verrills
Scheme		Role
MRSP Infrastructure Grant		Investigator
Total Amount	Funding Start	Funding Finish
$1,031,290	2008	2009
GNo:G0188622

PP2A: a novel target for leukaemia therapy$300,000
Funding Body: Cancer Council NSW

Project Team
Doctor Nikki Verrills, Conjoint Professor Leonie Ashman, Professor Alistair Sim, Associate Professor Danilo Perrotti, Assoc. Prof Timothy Hughes, Dr David Thomas
Scheme		Role
Research Grant		Investigator
Total Amount	Funding Start	Funding Finish
$300,000	2008	2010
GNo:G0187694

Role of tetraspanin proteins in human breast and prostate cancer$75,000
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Leonie Ashman, Doctor Severine Roselli
Scheme		Role
Mary Minto Sawyer Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$75,000	2008	2010
GNo:G0188187

FASEB Summer Research conference $2,500
Funding Body: University of Newcastle

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2,500	2008	2008
GNo:G0189020

2007 (6 grants)

FACSAria - Fluorescence activated cell sorter$300,000
Funding Body: Cancer Institute NSW

Project Team
Doctor Nikki Verrills, Conjoint Professor Leonie Ashman, Laureate Professor John Aitken, Professor Eileen McLaughlin, Professor Alistair Sim, Doctor Rick Thorne, Doctor Jennette Sakoff
Scheme		Role
Infrastructure Grants		Investigator
Total Amount	Funding Start	Funding Finish
$300,000	2007	2007
GNo:G0187666

HMRI Contribution toward FACSAria - Fluorescence activated cell sorter$52,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Nikki Verrills, Conjoint Professor Leonie Ashman, Laureate Professor John Aitken, Professor Eileen McLaughlin, Professor Alistair Sim, Doctor Rick Thorne, Doctor Jennette Sakoff
Scheme		Role
Equipment Grant		Investigator
Total Amount	Funding Start	Funding Finish
$52,000	2007	2007
GNo:G0188207

Activity of kinase inhibitors on mutant forms of c-KIT in GIST and AML$27,500
Funding Body: Novartis Pharmaceuticals Australia Pty Limited

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$27,500	2007	2007
GNo:G0188467

Polymerase Chain Reaction (PCR) machine and Spectrophotometer$20,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Leonie Ashman, Professor Alistair Sim, Doctor Nikki Verrills
Scheme		Role
Equipment Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$20,000	2007	2007
GNo:G0188195

Regulation of cancer cell behaviour by tetraspanin molecular complexes$16,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Judith Scott, Conjoint Professor Leonie Ashman
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$16,000	2007	2007
GNo:G0187242

Beatson International Cancer Conference Molecular Cancer Thereapies: new challenges and horizons, Caledonian University, Glasgow, UK, 17/6/2007 - 20/6/2007$2,500
Funding Body: University of Newcastle

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2,500	2007	2007
GNo:G0187736

2006 (4 grants)

2006 Research Fellowship$776,824
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Research Fellowships		Chief Investigator
Total Amount	Funding Start	Funding Finish
$776,824	2006	2011
GNo:G0185093

PRC - Priority Research Centre for Bioinformatics, Biomarker Discovery & Information-Based Medicine (CIBM)$621,143
Funding Body: University of Newcastle

Project Team
Professor Pablo Moscato, Professor Rodney Scott, Professor John Rostas, Professor John Forbes, Conjoint Professor Peter Hersey, Conjoint Professor Stephen Ackland, Conjoint Professor Wayne Smith, Emeritus Professor Peter Dunkley, Conjoint Professor Leonie Ashman, Professor John Attia, Associate Professor Phillip Dickson, Associate Professor Liz Milward, Professor Alistair Sim, Associate Professor Paul Tooney, Associate Professor Regina Berretta, Conjoint Professor David Sibbritt, Conjoint Professor Chris Levi, Professor Xu Dong Zhang, Conjoint Associate Professor Patricia Crock, Conjoint Associate Professor Jeannette Lechner-Scott
Scheme		Role
Priority Research Centre		Investigator
Total Amount	Funding Start	Funding Finish
$621,143	2006	2013
GNo:G0186919

Structural studies of the binding of clinically relevant small-molecule injibitors to wildtype and mutant receptor tyrosine kinases$20,000
Funding Body: University of Newcastle

Project Team
Conjoint Associate Professor Renate Griffith, Conjoint Professor Leonie Ashman
Scheme		Role
Pilot Grant		Investigator
Total Amount	Funding Start	Funding Finish
$20,000	2006	2007
GNo:G0186710

BioRad Mini-PROTEAN3 Electrophoresis system$995
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Leonie Ashman, Associate Professor Phillip Dickson, Emeritus Professor Peter Dunkley, Professor John Rostas, Professor Judith Scott, Professor Alistair Sim, Doctor Nikki Verrills
Scheme		Role
Equipment Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$995	2006	2006
GNo:G0187280

2005 (9 grants)

Role of the tetraspanin CD151 in epithelial biology and cancer$447,750
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$447,750	2005	2007
GNo:G0183903

CD151 and functional overlap in tetraspanins$219,303
Funding Body: ARC (Australian Research Council)

Project Team
Conjoint Professor Leonie Ashman, Dr Mark Wright
Scheme		Role
Discovery Projects		Chief Investigator
Total Amount	Funding Start	Funding Finish
$219,303	2005	2007
GNo:G0184421

Protein kinase inhibitors for the treatment of acute myeloid leukaemia$217,500
Funding Body: Anthony Rothe Memorial Trust

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Research Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$217,500	2005	2007
GNo:G0184574

High throughput proteomics - Thermo Finnigan ProteomeX LCQ Integrated Proteomicis Workstation$207,189
Funding Body: ARC (Australian Research Council)

Project Team
Laureate Professor John Aitken, Professor Eileen McLaughlin, Professor Peter Lewis, Conjoint Associate Professor Renate Griffith, Conjoint Professor Ray Rose, Emeritus Professor John Patrick, Associate Professor David McCurdy, Professor Adam McCluskey, Emeritus Professor Ellak Von Nagy-Felsobuki, Emeritus Professor Peter Dunkley, Associate Professor Phillip Dickson, Professor John Rostas, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Professor Paul Foster, Conjoint Professor Peter Gibson, Professor Roger Smith, Professor Alistair Sim, Associate Professor Paul Tooney, Dr Fraser Ross
Scheme		Role
Linkage Infrastructure Equipment & Facilities (LIEF)		Investigator
Total Amount	Funding Start	Funding Finish
$207,189	2005	2005
GNo:G0184185

Mechanisms of drug resistance in acute myeloid leukaemia$156,200
Funding Body: Leukaemia Foundation of NSW

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Research Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$156,200	2005	2006
GNo:G0184615

2005 RIBG allocation$89,711
Funding Body: University of Newcastle

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Research Infrastructure Block Grant (RIBG)		Chief Investigator
Total Amount	Funding Start	Funding Finish
$89,711	2005	2005
GNo:G0185800

How the cell surface protein, CD151 promotes invasive behaviour in breast cancer$15,000
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Mary Minto Sawyer Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$15,000	2005	2005
GNo:G0185658

Oolemmal receptors - the role of the tetraspanin CD151 in sperm-egg fusion$7,537
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin, Conjoint Professor Leonie Ashman
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$7,537	2005	2005
GNo:G0184625

International Tetraspanins mini-symposium, June 30-July 1 2005, Federation of American Societies for Experimental Biology Summer Research Conference 16-21 July 2005$2,400
Funding Body: University of Newcastle

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2,400	2005	2005
GNo:G0185496

2004 (5 grants)

Biacore3000-Expansion of Proteomics Facility$187,341
Funding Body: ARC (Australian Research Council)

Project Team
Professor Alistair Sim, Laureate Professor John Aitken, Emeritus Professor Peter Dunkley, Professor John Rostas, Associate Professor Phillip Dickson, Conjoint Professor Leonie Ashman, Professor Roger Smith, Professor Gordon Burns, Professor Adam McCluskey, Associate Professor Paul Tooney, Dr Fraser Ross, Conjoint Professor Ray Rose
Scheme		Role
Linkage Infrastructure Equipment & Facilities (LIEF)		Investigator
Total Amount	Funding Start	Funding Finish
$187,341	2004	2004
GNo:G0183030

New drugs targeting protein kinases$17,000
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Leonie Ashman, Professor Adam McCluskey
Scheme		Role
Research Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$17,000	2004	2004
GNo:G0183751

Characterisation of a novel recepto-mediated signal transduction pathway in human spermatozoa.$14,000
Funding Body: University of Newcastle

Project Team
Associate Professor Brett Nixon, Conjoint Professor Leonie Ashman
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$14,000	2004	2004
GNo:G0183444

Is CD151 a co-receptor for human papilloma virus$12,395
Funding Body: University of Newcastle

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$12,395	2004	2004
GNo:G0183418

FASEB Summer Research Conference: Advances in Tetraspanin Research, 19-24 June 2004, USA$2,400
Funding Body: University of Newcastle

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2,400	2004	2004
GNo:G0184098

2003 (3 grants)

Detection of mutations in c-kit in paediatric mastocytosis patient samples and structural analysis of the interaction between the D816VKit mutant and inhibitor$17,000
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Leonie Ashman, Dr Petranel Ferrao
Scheme		Role
Research Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$17,000	2003	2003
GNo:G0182632

Molecular basis of cellular localisation of a cell membrane protein, CD151.$15,500
Funding Body: University of Newcastle

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$15,500	2003	2003
GNo:G0182464

Beatson Conference: Cell signalling and Cancer, Glasgow, Scotland 6-9 July, 2003$2,400
Funding Body: University of Newcastle

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2,400	2003	2003
GNo:G0183163

2002 (9 grants)

Proteomic and Genomic Analysis Facility.$473,332
Funding Body: Wellcome Trust

Project Team
Professor Alistair Sim, Emeritus Professor Peter Dunkley, Professor John Rostas, Professor Rodney Scott, Conjoint Professor Leonie Ashman
Scheme		Role
Major Equipment Award		Investigator
Total Amount	Funding Start	Funding Finish
$473,332	2002	2004
GNo:G0181527

c-Kit signalling and cellular responses in haemopoietic cells$470,250
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Research Fellowships		Chief Investigator
Total Amount	Funding Start	Funding Finish
$470,250	2002	2005
GNo:G0181693

c-Kit signalling and cellular responses in haemopoietic cells$377,024
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$377,024	2002	2004
GNo:G0181692

Use of retroviral libraries to characterise mechanisms of drug resistance in leukaemia$240,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Dr Petranel Ferrao, Conjoint Professor Leonie Ashman, Dr A Zannettino, Dr T Hughes
Scheme		Role
Project Grant		Investigator
Total Amount	Funding Start	Funding Finish
$240,000	2002	2003
GNo:G0181690

Molecular determinants of subcellular localisation and function of the transmembrane 4 superfamily protein, PETA-3$107,512
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Project Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$107,512	2002	2002
GNo:G0181691

Role of PETA-3/CD151 in epithelial cancer invasion and metastasis.$70,008
Funding Body: Cancer Council NSW

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Research Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$70,008	2002	2002
GNo:G0181686

Peltier Thermal Cycler and associated equipment essential for establishing cDNA Retroviral Libraries$21,315
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Leonie Ashman, Dr Petranel Ferrao, Professor Gordon Burns, Professor Alistair Sim, Emeritus Professor Peter Dunkley, Professor John Rostas, Associate Professor Phillip Dickson, Professor Dirk Van Helden, Dr Perry Hartfield
Scheme		Role
Equipment Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$21,315	2002	2002
GNo:G0181919

A tissue culture system for antibody production$14,265
Funding Body: University of Newcastle

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
New Staff Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$14,265	2002	2002
GNo:G0182574

FASEB Summer Research Conference: 2nd International Conf. on Tetraspanin Proteins Tuscan, AZ, USA, 15 - 20 June, 2002$2,500
Funding Body: University of Newcastle

Project Team
Conjoint Professor Leonie Ashman
Scheme		Role
Travel Grant		Chief Investigator
Total Amount	Funding Start	Funding Finish
$2,500	2002	2002
GNo:G0181991

2001 (5 grants)

c-KIT signalling and cellular responses in haemopoietic cells.$125,688
Funding Body: National Health & Medical Research Council

Scheme		Role
Project		Chief Investigator
Total Amount	Funding Start	Funding Finish
$125,688	2001	2001
GNo:17563889

Molecular determinants of subcellular localisation and function of the transmembrane 4 superfamily protein, PETA-3.$105,162
Funding Body: National Health & Medical Research Council

Scheme		Role
Project		Chief Investigator
Total Amount	Funding Start	Funding Finish
$105,162	2001	2001
GNo:17563958

c-KIT signalling and cellular responses in haemopoietic cells.$85,000
Funding Body: National Health & Medical Research Council

Scheme		Role
Research Fellowship		Chief Investigator
Total Amount	Funding Start	Funding Finish
$85,000	2001	2001
GNo:17563802

Role of PETA-3/CD151 in epithelial cancer invasion and metastasis.$60,308
Funding Body: Cancer Council SA

Scheme		Role
Project		Chief Investigator
Total Amount	Funding Start	Funding Finish
$60,308	2001	2001
GNo:17564642

Use of retroviral expression libraries to characterise mechanisms of drug resistance in leukaemia, $12,000
Funding Body: National Health & Medical Research Council

Scheme		Role
Project		Investigator
Total Amount	Funding Start	Funding Finish
$12,000	2001	2001
GNo:17564584

Edit

Research Supervision

Number of current supervisions	4
Total current UoN PhD EFTSL	0.5

For supervisions undertaken at an institution other that the University of Newcastle, details are shown in italics, and the institution name is listed below the program name.

Current Supervision

Commenced	Proposed Completion	Program	Supervisor Type	Research Title
2011	2015	PhD (Medical Biochemistry)	Co-Supervisor	The Role of CD151 in Glomerular Diseases
2011	2015	PhD (Medical Biochemistry)	Co-Supervisor	An Investigation into Micro-RNA Regulation of Tetraspanins CD151 and CD9 in Breast and Prostate Cancer Progression
2008	2012	PhD (Medical Biochemistry)	Principal Supervisor	Tetraspanins as Biomarkers and Causative Proteins in Prostate Cancer
2008	2012	PhD (Medical Biochemistry)	Co-Supervisor	Targeting PP2A Activation as a Novel Therapeutic Strategy for Receptor Tyrosine Kinase Driven Leukemia

Past Supervision

Year	Program	Supervisor Type	Research Title
2013	PhD (Medical Genetics)	Co-Supervisor	Activating Kinase Mutations in Melanoma
2010	PhD (Medical Biochemistry)	Co-Supervisor	Regulation of the Tumour Suppressor PP2A by Oncogenic Tyrosine Kinases
2010	PhD (Medical Biochemistry)	Principal Supervisor	Small Molecule Inhibitors for Type III Receptor Tyrosine Kinases
2009	PhD (Medical Biochemistry)	Principal Supervisor	c-KIT Polymorphisms in Pediatric Mastocytosis and Comparative Analysis of Wild Type c-KIT and the Asp816Val Mutant
2007	M Sc (Medical Biochemistry)[R]	Principal Supervisor	The Role of the Tetraspanin CD151 in Integrin/Growth Factor Receptor Complexes and Its Influence on Cancer Cell Behaviour
2005	PhD (Medical Biochemistry)	Principal Supervisor	Resistance to imatinib (STI 571) conferred by point mutations of Kit and BCR/ABL
2004	PHD Biochemistry & Cell Biology University of Adelaide	Principal Supervisor	Molecular and Cellular Studies of Isoforms of c-KIT
2004	PhD (Medical Biochemistry)	Sole Supervisor	Subcellular Localisation and Internalisation of the Tetraspanin, CD151: Role of the Cytoplasmic Domains
2003	PHD Behavioural Science N.E.C. University of Adelaide	Sole Supervisor	Receptor tyrosine kinase c-KIT:signal transduction and biological response
2002	PHD Biochemistry & Cell Biology University of Adelaide	Sole Supervisor	Function of the soluble c-KIT extracellular domain

Edit

Conjoint Professor Leonie Ashman

Work Phone	(08) 8376 9069
Cell / Mobile Phone	0419840829
Email	Leonie.Ashman@newcastle.edu.au
Position	Conjoint Professor School of Biomedical Sciences and Pharmacy Faculty of Health and Medicine The University of Newcastle, Australia
Focus Area	Medical Biochemistry
Office	-, -, Adelaide SA
URL:	www.newcastle.edu.au/profile/leonie-ashman

Staff Directory

Staff Profile

Career Summary

Biography

Qualifications

Research

Research keywords

Research expertise

Fields of Research

Memberships

Committee/Associations (relevant to research).

NHMRC Committee

Appointments

Invitations

Administrative

Administrative expertise

Teaching

Teaching keywords

Teaching expertise

Publications

Grants and Funding

Summary

2013 (1 grants)

Ultra-Low Temperature Cryogenic Freezer$24,596Funding Body: NHMRC (National Health & Medical Research Council)

2012 (4 grants)

The Hunter Cancer Biobank (HCB): Maximising community value through validation, annotation and distribution throughout NSW$292,300Funding Body: Cancer Institute NSW

High-Resolution Isoelectric Phosphoprotein Signalling System for Signalling Research, Biomarker Validation and Drug Development – Equipment Grant$143,394Funding Body: Hunter Medical Research Institute

Microscopic illumination system for advanced fluorescent protein technology$34,000Funding Body: NHMRC (National Health & Medical Research Council)

Does Ubiquitination control the altered expression of tetraspanin proteins in Breast Cancer?$25,000Funding Body: Hunter Medical Research Institute

2011 (3 grants)

Hunter translational cancer research unit$1,693,333Funding Body: Cancer Institute NSW

Identifying the mechanisms underlying altered expression and mode of action of tetraspanins CD151 and CD9 in metastasis: progression to targeted treatment for prostate cancer$375,000Funding Body: Prostate Cancer Foundation of Australia

Investigation of the function of CD151 in the glomerular filtration barrier and identification of genetic modifiers of glomerular diseases$25,000Funding Body: University of Newcastle

2010 (4 grants)

HMRI MRSP Infrastructure Grant (10-11) - CANCER$504,071Funding Body: Hunter Medical Research Institute

Laser microdissection microscopy system for cell and development biology$350,000Funding Body: ARC (Australian Research Council)

Laser microdissection microscopy system for cell and development biology$215,000Funding Body: University of Newcastle

ABI 7500 Real Time PCR System $34,000Funding Body: NHMRC (National Health & Medical Research Council)

2009 (9 grants)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000Funding Body: ARC (Australian Research Council)

Tetraspanin proteins in prostate cancer progression and prognosis$341,000Funding Body: Cancer Council NSW

MRSP Infrastructure (09-10) Cancer$283,916Funding Body: Hunter Medical Research Institute

Confocal Laser Scanning Microscopy for Live Cell Imaging$275,000Funding Body: ARC (Australian Research Council)

IVIS Lumina II fluorescence and bioluminescence imager for in vivo analysis of tumour growth and metastasis in mouse models$153,200Funding Body: Cancer Institute NSW

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000Funding Body: ARC (Australian Research Council)

Study of c-KIT mutations in familial gastrointestinal stromal tumours and malignant melanoma$44,720Funding Body: Pfizer Australia

Identification of genetic modifiers of kidney disease$25,000Funding Body: Hunter Medical Research Institute

3rd European Conference on Tetraspanins, Paris, 10-11 September 2009$1,175Funding Body: University of Newcastle

2008 (4 grants)

HMRI Cancer Research Program - MRSP Infrastructure$1,031,290Funding Body: Hunter Medical Research Institute

PP2A: a novel target for leukaemia therapy$300,000Funding Body: Cancer Council NSW

Role of tetraspanin proteins in human breast and prostate cancer$75,000Funding Body: Hunter Medical Research Institute

FASEB Summer Research conference $2,500Funding Body: University of Newcastle

2007 (6 grants)

FACSAria - Fluorescence activated cell sorter$300,000Funding Body: Cancer Institute NSW

HMRI Contribution toward FACSAria - Fluorescence activated cell sorter$52,000Funding Body: Hunter Medical Research Institute

Activity of kinase inhibitors on mutant forms of c-KIT in GIST and AML$27,500Funding Body: Novartis Pharmaceuticals Australia Pty Limited

Polymerase Chain Reaction (PCR) machine and Spectrophotometer$20,000Funding Body: NHMRC (National Health & Medical Research Council)

Regulation of cancer cell behaviour by tetraspanin molecular complexes$16,000Funding Body: Hunter Medical Research Institute

Beatson International Cancer Conference Molecular Cancer Thereapies: new challenges and horizons, Caledonian University, Glasgow, UK, 17/6/2007 - 20/6/2007$2,500Funding Body: University of Newcastle

2006 (4 grants)

2006 Research Fellowship$776,824Funding Body: NHMRC (National Health & Medical Research Council)

PRC - Priority Research Centre for Bioinformatics, Biomarker Discovery & Information-Based Medicine (CIBM)$621,143Funding Body: University of Newcastle

Structural studies of the binding of clinically relevant small-molecule injibitors to wildtype and mutant receptor tyrosine kinases$20,000Funding Body: University of Newcastle

BioRad Mini-PROTEAN3 Electrophoresis system$995Funding Body: Hunter Medical Research Institute

2005 (9 grants)

Role of the tetraspanin CD151 in epithelial biology and cancer$447,750Funding Body: NHMRC (National Health & Medical Research Council)

CD151 and functional overlap in tetraspanins$219,303Funding Body: ARC (Australian Research Council)

Protein kinase inhibitors for the treatment of acute myeloid leukaemia$217,500Funding Body: Anthony Rothe Memorial Trust

High throughput proteomics - Thermo Finnigan ProteomeX LCQ Integrated Proteomicis Workstation$207,189Funding Body: ARC (Australian Research Council)

Mechanisms of drug resistance in acute myeloid leukaemia$156,200Funding Body: Leukaemia Foundation of NSW

2005 RIBG allocation$89,711Funding Body: University of Newcastle

How the cell surface protein, CD151 promotes invasive behaviour in breast cancer$15,000Funding Body: Hunter Medical Research Institute

Oolemmal receptors - the role of the tetraspanin CD151 in sperm-egg fusion$7,537Funding Body: University of Newcastle

International Tetraspanins mini-symposium, June 30-July 1 2005, Federation of American Societies for Experimental Biology Summer Research Conference 16-21 July 2005$2,400Funding Body: University of Newcastle

2004 (5 grants)

Biacore3000-Expansion of Proteomics Facility$187,341Funding Body: ARC (Australian Research Council)

New drugs targeting protein kinases$17,000Funding Body: Hunter Medical Research Institute

Characterisation of a novel recepto-mediated signal transduction pathway in human spermatozoa.$14,000Funding Body: University of Newcastle

Is CD151 a co-receptor for human papilloma virus$12,395Funding Body: University of Newcastle

Ultra-Low Temperature Cryogenic Freezer$24,596
Funding Body: NHMRC (National Health & Medical Research Council)

The Hunter Cancer Biobank (HCB): Maximising community value through validation, annotation and distribution throughout NSW$292,300
Funding Body: Cancer Institute NSW

High-Resolution Isoelectric Phosphoprotein Signalling System for Signalling Research, Biomarker Validation and Drug Development – Equipment Grant$143,394
Funding Body: Hunter Medical Research Institute

Microscopic illumination system for advanced fluorescent protein technology$34,000
Funding Body: NHMRC (National Health & Medical Research Council)

Does Ubiquitination control the altered expression of tetraspanin proteins in Breast Cancer?$25,000
Funding Body: Hunter Medical Research Institute

Hunter translational cancer research unit$1,693,333
Funding Body: Cancer Institute NSW

Identifying the mechanisms underlying altered expression and mode of action of tetraspanins CD151 and CD9 in metastasis: progression to targeted treatment for prostate cancer$375,000
Funding Body: Prostate Cancer Foundation of Australia

Investigation of the function of CD151 in the glomerular filtration barrier and identification of genetic modifiers of glomerular diseases$25,000
Funding Body: University of Newcastle

HMRI MRSP Infrastructure Grant (10-11) - CANCER$504,071
Funding Body: Hunter Medical Research Institute

Laser microdissection microscopy system for cell and development biology$350,000
Funding Body: ARC (Australian Research Council)

Laser microdissection microscopy system for cell and development biology$215,000
Funding Body: University of Newcastle

ABI 7500 Real Time PCR System $34,000
Funding Body: NHMRC (National Health & Medical Research Council)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000
Funding Body: ARC (Australian Research Council)

Tetraspanin proteins in prostate cancer progression and prognosis$341,000
Funding Body: Cancer Council NSW

MRSP Infrastructure (09-10) Cancer$283,916
Funding Body: Hunter Medical Research Institute

Confocal Laser Scanning Microscopy for Live Cell Imaging$275,000
Funding Body: ARC (Australian Research Council)

IVIS Lumina II fluorescence and bioluminescence imager for in vivo analysis of tumour growth and metastasis in mouse models$153,200
Funding Body: Cancer Institute NSW

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000
Funding Body: ARC (Australian Research Council)

Study of c-KIT mutations in familial gastrointestinal stromal tumours and malignant melanoma$44,720
Funding Body: Pfizer Australia

Identification of genetic modifiers of kidney disease$25,000
Funding Body: Hunter Medical Research Institute

3rd European Conference on Tetraspanins, Paris, 10-11 September 2009$1,175
Funding Body: University of Newcastle

HMRI Cancer Research Program - MRSP Infrastructure$1,031,290
Funding Body: Hunter Medical Research Institute

PP2A: a novel target for leukaemia therapy$300,000
Funding Body: Cancer Council NSW

Role of tetraspanin proteins in human breast and prostate cancer$75,000
Funding Body: Hunter Medical Research Institute

FASEB Summer Research conference $2,500
Funding Body: University of Newcastle

FACSAria - Fluorescence activated cell sorter$300,000
Funding Body: Cancer Institute NSW

HMRI Contribution toward FACSAria - Fluorescence activated cell sorter$52,000
Funding Body: Hunter Medical Research Institute

Activity of kinase inhibitors on mutant forms of c-KIT in GIST and AML$27,500
Funding Body: Novartis Pharmaceuticals Australia Pty Limited

Polymerase Chain Reaction (PCR) machine and Spectrophotometer$20,000
Funding Body: NHMRC (National Health & Medical Research Council)

Regulation of cancer cell behaviour by tetraspanin molecular complexes$16,000
Funding Body: Hunter Medical Research Institute

Beatson International Cancer Conference Molecular Cancer Thereapies: new challenges and horizons, Caledonian University, Glasgow, UK, 17/6/2007 - 20/6/2007$2,500
Funding Body: University of Newcastle

2006 Research Fellowship$776,824
Funding Body: NHMRC (National Health & Medical Research Council)

PRC - Priority Research Centre for Bioinformatics, Biomarker Discovery & Information-Based Medicine (CIBM)$621,143
Funding Body: University of Newcastle

Structural studies of the binding of clinically relevant small-molecule injibitors to wildtype and mutant receptor tyrosine kinases$20,000
Funding Body: University of Newcastle

BioRad Mini-PROTEAN3 Electrophoresis system$995
Funding Body: Hunter Medical Research Institute

Role of the tetraspanin CD151 in epithelial biology and cancer$447,750
Funding Body: NHMRC (National Health & Medical Research Council)

CD151 and functional overlap in tetraspanins$219,303
Funding Body: ARC (Australian Research Council)

Protein kinase inhibitors for the treatment of acute myeloid leukaemia$217,500
Funding Body: Anthony Rothe Memorial Trust

High throughput proteomics - Thermo Finnigan ProteomeX LCQ Integrated Proteomicis Workstation$207,189
Funding Body: ARC (Australian Research Council)

Mechanisms of drug resistance in acute myeloid leukaemia$156,200
Funding Body: Leukaemia Foundation of NSW

2005 RIBG allocation$89,711
Funding Body: University of Newcastle

How the cell surface protein, CD151 promotes invasive behaviour in breast cancer$15,000
Funding Body: Hunter Medical Research Institute

Oolemmal receptors - the role of the tetraspanin CD151 in sperm-egg fusion$7,537
Funding Body: University of Newcastle

International Tetraspanins mini-symposium, June 30-July 1 2005, Federation of American Societies for Experimental Biology Summer Research Conference 16-21 July 2005$2,400
Funding Body: University of Newcastle

Biacore3000-Expansion of Proteomics Facility$187,341
Funding Body: ARC (Australian Research Council)

New drugs targeting protein kinases$17,000
Funding Body: Hunter Medical Research Institute

Characterisation of a novel recepto-mediated signal transduction pathway in human spermatozoa.$14,000
Funding Body: University of Newcastle

Is CD151 a co-receptor for human papilloma virus$12,395
Funding Body: University of Newcastle

FASEB Summer Research Conference: Advances in Tetraspanin Research, 19-24 June 2004, USA$2,400
Funding Body: University of Newcastle

Detection of mutations in c-kit in paediatric mastocytosis patient samples and structural analysis of the interaction between the D816VKit mutant and inhibitor$17,000
Funding Body: Hunter Medical Research Institute

Molecular basis of cellular localisation of a cell membrane protein, CD151.$15,500
Funding Body: University of Newcastle

Beatson Conference: Cell signalling and Cancer, Glasgow, Scotland 6-9 July, 2003$2,400
Funding Body: University of Newcastle

Proteomic and Genomic Analysis Facility.$473,332
Funding Body: Wellcome Trust

c-Kit signalling and cellular responses in haemopoietic cells$470,250
Funding Body: NHMRC (National Health & Medical Research Council)

c-Kit signalling and cellular responses in haemopoietic cells$377,024
Funding Body: NHMRC (National Health & Medical Research Council)

Use of retroviral libraries to characterise mechanisms of drug resistance in leukaemia$240,000
Funding Body: NHMRC (National Health & Medical Research Council)

Molecular determinants of subcellular localisation and function of the transmembrane 4 superfamily protein, PETA-3$107,512
Funding Body: NHMRC (National Health & Medical Research Council)

Role of PETA-3/CD151 in epithelial cancer invasion and metastasis.$70,008
Funding Body: Cancer Council NSW

Peltier Thermal Cycler and associated equipment essential for establishing cDNA Retroviral Libraries$21,315
Funding Body: NHMRC (National Health & Medical Research Council)

A tissue culture system for antibody production$14,265
Funding Body: University of Newcastle

FASEB Summer Research Conference: 2nd International Conf. on Tetraspanin Proteins Tuscan, AZ, USA, 15 - 20 June, 2002$2,500
Funding Body: University of Newcastle

c-KIT signalling and cellular responses in haemopoietic cells.$125,688
Funding Body: National Health & Medical Research Council

Molecular determinants of subcellular localisation and function of the transmembrane 4 superfamily protein, PETA-3.$105,162
Funding Body: National Health & Medical Research Council

c-KIT signalling and cellular responses in haemopoietic cells.$85,000
Funding Body: National Health & Medical Research Council

Role of PETA-3/CD151 in epithelial cancer invasion and metastasis.$60,308
Funding Body: Cancer Council SA

Use of retroviral expression libraries to characterise mechanisms of drug resistance in leukaemia, $12,000
Funding Body: National Health & Medical Research Council