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Career Summary

Biography

Professor Ashman is a NHMRC Principal Research Fellow and Gladys Brawn Professorial Fellow. She came to the University of Newcastle in 2002 from the Hanson Centre for Cancer Research and the University of Adelaide. In her career spanning 35 years she has published 150 papers in refereed international journals and conference proceedings. Career highlights include identification at the protein level of the receptor tyrosine kinase c-KIT, publication of the first monoclonal antibody to it, and the first description of c-KIT expression by haemopoietic progenitor cells in bone marrow. She has an ongoing interest in the role of mutant c-KIT in acute myeloid leukaemia and other cancers and in new drugs that target this receptor. Prof Ashman's group also identified a novel tetraspanin protein, CD151, cloned the gene, and generated the first CD151 knock-out mice. Work in this and other laboratories has shown that the CD151 protein modifies cell adhesion and migration and plays an important role in the spread (metastasis) of cancer.

Qualifications

  • PhD, University of Adelaide
  • Bachelor of Science (Honours), Flinders University

Research

Research keywords

  • Cell and Molecular biology of cancer

Research expertise

I was trained as a biochemist but worked for many years in immunology. In now consider myself as a cell and molecular biologist. The underlying theme of my research has always been cancer, its cellular and molecular biology and development of novel approaches to diagnosis and treatment. Major themes have been haemopoiesis and leukaemia, regulation of cellular behaviour by cell surface receptors, cellular signalling and development of novel targetted therapeutics.

Fields of Research

CodeDescriptionPercentage
060100Biochemistry And Cell Biology60
111299Oncology And Carcinogenesis Not Elsewhere Classified30
110199Medical Biochemistry And Metabolomics Not Elsewhere Classified10

Memberships

Committee/Associations (relevant to research).

  • Joint convenor - Hunter Medical Research Institute International Conferences on Translational Cancer Research, 2004, 2006, 2008

NHMRC Committee

  • Member - Grant Review Panel - Cell Biology 2005,2006
  • Member, 2001, 2002 - Research Fellowship Advisory Panel A

Appointments

Recipient
University of Newcastle (Australia)
01/01/2006 - 01/12/2010
Fellowship
National Health & Medical Research Council (Australia)
01/01/2006 - 01/12/2011

Invitations

Glivec Solid Tumour Advisory Board
Novartis Pharma, United States (Conference Presentation - non published.)
2001
Summer Research Conference: tetraspanins
Federation of American Societies of Experimental Biology, United States (Conference Presentation - non published.)
2004

Administrative

Administrative expertise

Initiated and coordinated B Health Sci (Hons) program in Experimental Medicine at Adelaide University,

Member, Graduate Studies Committee and Board of Research Education and Development at Adelaide University

Elected Staff Representative, Hanson Centre Executive

Member, Hanson Institute Strategic Advisory Committee

Member, NHMRC Research Fellowships Advisory Panel, 2001, 2002.

Member NHMRC Grant Review panel, 2005, 2006.

At University of Newcastle:

Member, Faculty of Health Research Management Committee (2002, 2003).

Research Portfolio Committee, 2004 (casual vacancy)

Member of multiple appointments committess and grant review panels.

Teaching

Teaching keywords

  • Cancer Biology

Teaching expertise

While I have always been employed in "Research Only" positions I have contributed extensively to teaching both at the University of Adelaide and the University of Newcastle. Currently I teach into the B Biomed Sci program in my areas of research expertise (Cancer biology and novel drug development).

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Highlighted Publications

For publications that are currently unpublished or in-press, details are shown in italics.

YearCitationAltmetricsLink
2002Frost MJ, Ferrao PT, Hughes T, Ashman LK, 'Juxtamembrane Mutant V560GKit Is more Sensitive to Imatinib (ST1571) Compared with Wild-Type c-Kit Whereas the Kinase Domain Mutant D816VKit is Resistant', Molecular Cancer Therapeutics, 1 1115-1124 (2002) [C1]
2004Moseley GW, Lau L-M, Sheng K-C, Apostolopoulos V, Stanley EG, Jackson DE, et al., 'Characterization of Mice Lacking the Tetraspanin Superfamily Member CD151', Molecular and Cellular Biology, 24 5978-5988 (2004) [C1]
2003Ferrao PT, Frost MJ, Siah SP, Ashman LK, 'Overexpression of P-glycoprotein in K562 cells does not confer resistance to the growth inhibitory effects of imatinib (STI571) in vitro', Blood, 102 4499-4503 (2003) [C1]
2006Cowin AJ, Adams D, Geary SM, Wright MD, Jones JCR, Ashman LK, 'Wound healing is defective in mice lacking tetraspanin CD151', Journal of Investigative Dermatology, 126 680-689 (2006) [C1]

Publications

For publications that are currently unpublished or in-press, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Chapter (1 outputs)

YearCitationAltmetricsLink
2013Ashman LK, Zoller M, 'Tetraspanins in Cancer', Tetraspanins, Springer, Dordrecht 257-298 (2013) [B1]

Journal article (187 outputs)

YearCitationAltmetricsLink
2014Roselli S, Kahl RG, Copeland BT, Naylor MJ, Weidenhofer J, Muller WJ, Ashman LK, 'Deletion of Cd151 reduces mammary tumorigenesis in the MMTV/PyMT mouse model.', BMC Cancer, 14 509 (2014)
2013Mashkani B, Odell AF, Byrnes EM, Griffith R, Ashman LK, 'Expression of biologically active human colony stimulating factor-1 in Pichia pastoris', Protein Expression and Purification, 88 93-97 (2013) [C1]
2013Ashman LK, Griffith R, 'Therapeutic targeting of c-KIT in cancer', EXPERT OPINION ON INVESTIGATIONAL DRUGS, 22 103-115 (2013) [C1]
2013Copeland BT, Bowman MJ, Boucheix C, Ashman LK, 'Knockout of the tetraspanin Cd9 in the TRAMP model of de novo prostate cancer increases spontaneous metastases in an organ-specific manner', International Journal of Cancer, 133 1803-1812 (2013) [C1]
2013Copeland BT, Bowman MJ, Ashman LK, 'Genetic Ablation of the Tetraspanin CD151 Reduces Spontaneous Metastatic Spread of Prostate Cancer in the TRAMP Model', MOLECULAR CANCER RESEARCH, 11 95-105 (2013) [C1]
2013Ashman LK, 'Renal disease as a potential compounding factor in carcinogenesis experiments with Cd151-null mice', ONCOGENE, 32 4457-4457 (2013) [C3]
2011Ashman LK, 'Cell line models identify different sensitivity of mutant forms of c-KIT to kinase inhibitory drugs and predict the response of patients to therapy', Molecular Cancer Therapeutics, 10 2032-2033 (2011) [C3]
2011Vilain RE, Dudding TE, Braye SG, Groombridge C, Meldrum C, Spigelman AD, et al., 'Can a familial gastrointestinal tumour syndrome be allelic with Waardenburg syndrome?', Clinical Genetics, 79 554-560 (2011) [C3]
2011Moheimani F, Ashman LK, Wright MD, Jackson DE, 'Novel molecular association of ADP purinergic receptor, P2Y12 with tetraspanin superfamily member, CD151 in human platelets', JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 9 776-777 (2011)
2010Mashkani B, Griffith R, Ashman LK, 'Colony stimulating factor-1 receptor as a target for small molecule inhibitors', Bioorganic & Medicinal Chemistry, 18 1789-1797 (2010) [C1]
2010Ang J, Fang B-L, Ashman LK, Frauman AG, 'The migration and invasion of human prostate cancer cell lines involves CD151 expression', Oncology Reports, 24 1593-1597 (2010) [C1]
2010Roberts KG, Smith AM, McDougall FK, Carpenter HC, Horan MP, Neviani P, et al., 'Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT+ cancers', Cancer Research, 70 5438-5447 (2010) [C1]
2009Protty MB, Watkins NA, Colombo D, Thomas SG, Heath VL, Herbert JMJ, et al., 'Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains', Biochemical Journal, 417 391-400 (2009) [C1]
2009Orlowski E, Chand R, Yip J, Wong C, Goschnick MW, Wright MD, et al., 'A platelet tetraspanin superfamily member, CD151, is required for regulation of thrombus growth and stability in vivo', Journal of Thrombosis and Haemostasis, 7 2074-2084 (2009) [C1]
2009Sheng K-C, Van Spriel AB, Gartlan KH, Sofi M, Apostolopoulos V, Ashman LK, Wright MD, 'Tetraspanins CD37 and CD151 differentially regulate Ag presentation and T-cell co-stimulation by DC', European Journal of Immunology, 39 50-55 (2009) [C1]
2009Weidenhofer JC, Ashman LK, 'CD151 (CD151 molecule (Raph blood group))', Atlas of Genetics and Cytogenetics in Oncology and Haematology, - (2009) [C1]

Co-authors: Judith Weidenhofer

2008Foster RC, Byrnes EM, Meldrum C, Griffith R, Ross G, Upjohn E, et al., 'Association of paediatric mastocytosis with a polymorphism resulting in an amino acid substitution (M541L) in the transmembrane domain of c-KIT', British Journal of Dermatology, 159 1160-1169 (2008) [C1]
2008Yamada M, Tamura Y, Sanzen N, Sato-Nishiuchi R, Hasegawa H, Ashman LK, et al., 'Probing the interaction of tetraspanin CD151 with integrin alpha 3 beta 1 using a panel of monoclonal antibodies with distinct reactivities toward the CD151-integrin alpha 3 beta 1 complex', Biochemical Journal, 415 417-427 (2008) [C1]
2008Baleato R, Guthrie PL, Gubler M-C, Ashman LK, Roselli SM, 'Deletion of Cd151 results in a strain-dependent glomerular disease due to severe alterations of the glomerular basement membrane', American Journal of Pathology, 173 927-937 (2008) [C1]
2008Geary SM, Cowin AJ, Copeland BT, Baleato R, Miyazaki K, Ashman LK, 'The role of the tetraspanin CD151 in primary keratinocyte and fibroblast functions: Implications for wound healing', Experimental Cell Research, 314 2165-2175 (2008) [C1]
2008Baldwin G, Novitskaya V, Sadej R, Pochec E, Litynska A, Hartmann C, et al., 'Tetraspanin CD151 regulates glycosylation of alpha 3 beta 1 integrin', Journal of Biological Chemistry, 283 35445-35454 (2008) [C1]
2007Roberts KG, Odell AF, Byrnes EM, Baleato R, Griffith R, Lyons AB, Ashman LK, 'Resistance to c-KIT kinase inhibitors conferred by V654A mutation', Molecular Cancer Therapeutics, 6 1159-1166 (2007) [C1]
2007Young SM, Cambareri AC, Odell AF, Geary SM, Ashman LK, 'Early myeloid cells expressing c-KIT isoforms differ in signal transduction, survival and chemotactic responses to Stem Cell Factor', Cellular Signalling, 19 2572-2581 (2007) [C1]
2006Griffith R, Brown MN, McCluskey A, Ashman LK, 'Small molecule inhibitors of protein kinases in cancer - How to overcome resistance', Mini-Reviews in Medicinal Chemistry, 6 1101-1110 (2006) [C1]
2006Winterwood NE, Varzavand A, Meland MN, Ashman LK, Stipp CS, 'A critical role for tetraspanin CD151 in alpha 381 and alpha 684 integrin-dependent tumor cell functions on Laminin-5', Molecular Biology of the Cell, 17 2707-2721 (2006) [C1]
2006Young SM, Cambareri AC, Ashman LK, 'Role of c-KIT expression level and phosphatidylinositol 3-kinase activation in survival and proliferative responses of early myeloid cells', Cellular Signalling, 18 608-620 (2006) [C1]
2006Cowin AJ, Adams D, Geary SM, Wright MD, Jones JCR, Ashman LK, 'Wound healing is defective in mice lacking tetraspanin CD151', Journal of Investigative Dermatology, 126 680-689 (2006) [C1]
2005Gesierich S, Paret C, Hildebrand D, Weitz J, Zgraggen K, Schmitz-Winnenthal FH, et al., 'Colocalization of the tetraspanins, CO-029 and CD151, with integrins in human pancreatic adenocarcinoma: Impact on cell motility', Clinical Cancer Research, 11 2840-2852 (2005) [C1]
2005Cullinane C, Dorow DS, Kansara M, Conus N, Binns D, Hicks RJ, et al., 'An in vivo tumor model exploiting metabolic response as a biomarker for targeted drug development', Cancer Research, 65 9633-9636 (2005) [C1]
2005Nixon B, Paul JW, Spiller CM, Attwell-Heap AG, Ashman LK, Aitken RJ, 'Evidence for the involvement of PECAM-1 in a receptor mediated signal-transduction pathway regulating capacitation-associated tyrosine phosphorylation in human spermatozoa', Journal of Cell Science, 118 4865-4877 (2005) [C1]
2005Ang J, Lijovic M, Frauman AG, Ashman LK, Kan K, 'Low grade primary prostate cancer (vol 13, pg 1717, 2004)', CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 14 553-553 (2005)
2005Ang J, Lijovic M, Frauman AG, Ashman LK, Kahn K, 'Erratum: CD151 protein expression predicts the clinical outcome of low-grade primary prostate cancer better than histologic grading: A new prognostic indicator? (Cancer Epidemiology Biomarkers and Prevention (November 2004) 13, 11 (1717-1721))', Cancer Epidemiology Biomarkers and Prevention, 14 553-553 (2005)
2004Moseley GW, Lau L-M, Sheng K-C, Apostolopoulos V, Stanley EG, Jackson DE, et al., 'Characterization of Mice Lacking the Tetraspanin Superfamily Member CD151', Molecular and Cellular Biology, 24 5978-5988 (2004) [C1]
2004Foster RC, Griffith R, Ferrao PT, Ashman LK, 'Molecular basis of the constitutive activity and STI571 resistance of Asp816Val mutant KIT receptor tyrosine kinase', Journal of Molecular Graphics and Modelling, 23 139-152 (2004) [C1]
2004Ang J, Lijovic M, Ashman LK, Kan K, Frauman A, 'CD151 Protein Expression Predicts the Clinical Outcome of Low-Grade Primary Prostate Cancer Better than Histologic Grading: A New Prognostic Indicator?', Cancer Epidemiology, Biomarkers & Prevention, 13 1717-1721 (2004) [C1]
2004Lau L-M, Wee JL, Wright MD, Moseley GW, Hogarth PM, Ashman LK, Jackson DE, 'The tetraspanin superfamily member CD151 regulates outside-in integrin alpha IIb Beta 3 signaling and platelet function', Blood, 104 2368-2375 (2004) [C1]
2003To LB, Bashford J, Durrant S, Macmillan J, Schwarer AP, Prince HM, et al., 'Successful mobilisation of peripheral blood stem cell after addition of ancestim (stem cell factor) in patients who had failed a prior mobilisation with filgrastim (granulocyte colony stimulating factor) alone or with chemotherapy plus filgrastim', Bone Marrow Transplantation, 31 371-378 (2003) [C1]
2003Ferrao PT, Gonda T, Ashman LK, 'Constitutively active mutant D816VKit induces megakayocyte and mast cell differentiation of early haemopoietic cells from murine foetal liver', Leukemia Research, 27 547-555 (2003) [C1]
2003Thai LM, Ashman LK, Harbour SN, Hogarth M, Jackson D, 'Physical proximity and functional interplay of PECAM-1 with the Fc receptor FcyRIIa on the platelet plasma membrane', Blood, 102 3637-3645 (2003) [C1]
2003Ferrao PT, Frost MJ, Siah SP, Ashman LK, 'Overexpression of P-glycoprotein in K562 cells does not confer resistance to the growth inhibitory effects of imatinib (STI571) in vitro', Blood, 102 4499-4503 (2003) [C1]
2003Chattopadhyay N, Wang Z, Ashman LK, Brady-Kalnay SM, Kreidberg JA, 'Alpha3 beta1 integrin-CD151, a component of the cadherin-catenin complex, regulates PTPu expression and cell-cell adhesion', The Journal of Cell Biology, 163 1351-1362 (2003) [C1]
2003Voytyuk O, Lennartsson J, Mogi A, Caruana G, Courtneidge S, Ashman LK, Ronnstrand L, 'Src Family Kinases Are Involved in the Differential Signaling from Two Splice Forms of c-Kit', The Journal of Biological Chemistry, 278 9159-9166 (2003) [C1]
2003Charrin S, Manie S, Billard M, Ashman LK, Gerlier D, Boucheix C, Rubinstein E, 'Multiple levels of interactions within the tetraspanin web', Biochemical and Biophysical Research Communications, 304 107-112 (2003) [C1]
2002Ashman LK, 'CD151', Journal of Biological Regulators and Homeostatic Agents, 16 223-226 (2002) [C1]
2002Frost MJ, Ferrao PT, Hughes T, Ashman LK, 'Juxtamembrane Mutant V560GKit Is more Sensitive to Imatinib (ST1571) Compared with Wild-Type c-Kit Whereas the Kinase Domain Mutant D816VKit is Resistant', Molecular Cancer Therapeutics, 1 1115-1124 (2002) [C1]
2002Fletcher J, Fletcher C, Rubin B, Ashman LK, Corless C, Heinrich M, 'KIT Gene Mutations in Gastrointestinal Stromal Tumors - More Complex than Previously Recognized?', American Journal of Pathology, 161, No 2 737-738 (2002) [C3]
2001Berditchevksi F, Gilbert E, Griffiths MR, Fitter S, Ashman L, Jenner SJ, 'Analysis of the CD151-a3b1 integrin and CD151-tetraspanin interactions by mutagenesis 41165-41174 (2001) [C1]
2001Chian R, Young SM, Danilkovitch-Miagkova A, Ronnstrand L, Leonard E, Ferrao P, et al., 'PI3-kinase mediates transformation of hematopoietic cells by the V816 c-Kit mutant', Blood, 98 1365-1373 (2001) [C1]
2001Geary SM, Cambaren AC, Fitter S, Ashman LK, 'Differential tissue expression of epitopes of the tetraspanin CD151 recognised by monoclonal antibodies', Tissue Antigens, 58 142-153 (2001) [C1]
2001Chian RJ, Young S, Danilkovitch-Miagkova A, Ronnstrand L, Leonard E, Ferrao P, et al., 'Phosphatidylinositol 3 kinase contributes to the transformation of hematopoietic cells by the D816V c-Kit mutant', BLOOD, 98 1365-1373 (2001)
2001Ferrao P, Sincock P, Cole S, Ashman L, 'Intracellular P-gp contributes to functional drug efflux and resistance in acute myeloid leukaemia (vol 25, pg 395, 2001)', LEUKEMIA RESEARCH, 25 827-827 (2001)
2001Ferrao PT, Frost MJ, Coles CJ, Domaschenz RM, Hughes TP, Ashman LK, 'Activated mutant D816VKit confers resistance to chemotherapeutic drugs, irradiation and STI 571.', CLINICAL CANCER RESEARCH, 7 3742S-3742S (2001)
2001Ferrao P, Sincock P, Cole S, Ashman L, 'Intracellular P-gp contributes to functional drug efflux and resistance in acute myeloid leukaemia', LEUKEMIA RESEARCH, 25 395-405 (2001)
2001Berditchevski F, Gilbert E, Griffiths MR, Fitter S, Ashman L, Jenner SJ, 'Analysis of the CD151 center dot alpha(3)beta(1) integrin and CD151 center dot tetraspanin interactions by mutagenesis.', JOURNAL OF BIOLOGICAL CHEMISTRY, 276 41165-41174 (2001)
2000Linnekin D, Young S, Danilkovitch-Miagkova A, Ronnstrand L, Leonard E, Ferrao P, et al., 'PI3 kinase mediates transformation of hematopoietic cells by THF V816 c-Kit mutant.', BLOOD, 96 498A-498A (2000)
2000Chian R, Young S, Danilkovitch-Miagkova A, Ronnstrand L, Leonard E, Ferrao P, et al., 'P13 kinase mediates transformation of hematopoietic cells by the V816 c-Kit mutant', EXPERIMENTAL HEMATOLOGY, 28 1491-1491 (2000)
2000Ashman LK, Ferrao P, Cole SR, Cambareri AC, 'Effects of mutant c-Kit in early myeloid cells (vol 34, pg 451, 1997)', LEUKEMIA & LYMPHOMA, 37 233-243 (2000)
1999Caruana G, Cambareri AC, Ashman LK, 'Isoforms of c-KIT differ in activation of signalling pathways and transformation of NIH3T3 fibroblasts', ONCOGENE, 18 5573-5581 (1999)
1999Brach MA, Herrmann F, Kufe DW, 'Activation of the AP-1 transcription factor by arabinofuranosylcytosine in myeloid leukemia cells (Retraction of vol 79, pg 728, 1992)', BLOOD, 93 3573-3573 (1999)
1999Gibson MA, Leavesley DI, Ashman LK, 'Microfibril-associated glycoprotein-2 specifically interacts with a range of bovine and human cell types via alpha(v)beta(3) integrin', JOURNAL OF BIOLOGICAL CHEMISTRY, 274 13060-13065 (1999)
1999Linnekin D, Ashman L, Ferrao P, Chian R, Keller J, 'Signaling mechanisms of an oncogenic form of c-Kit in hematopoietic cells', EXPERIMENTAL HEMATOLOGY, 27 56-56 (1999)
1999Fitter S, Sincock PM, Jolliffe CN, Ashman LK, 'Transmembrane 4 superfamily protein CD151 (PETA-3) associates with beta(1) and alpha(IIb)beta(3) integrins in haemopoietic cell lines and modulates cell-cell adhesion', BIOCHEMICAL JOURNAL, 338 61-70 (1999)
1999Brach MA, Buhring HJ, Gruss HJ, Ashman LK, Ludwig WD, Mertelsmann RH, Herrmann F, 'Functional expression of c-kit by acute myelogenous leukemia blasts is enhanced by tumor necrosis factor-alpha through posttranscriptional mRNA stabilization by a labile protein (Retraction of vol 80, pg 1224, 1992)', BLOOD, 93 3573-3573 (1999)
1999Heberlein C, Friel J, Laker C, von Laer D, Bergholz U, Bogel M, et al., 'Downregulation of c-kit (stem cell factor receptor) in transformed hematopoietic precursor cells by stroma cells', BLOOD, 93 554-563 (1999)
1999Ashman LK, 'The biology of stem cell factor and its receptor C-kit', INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 31 1037-1051 (1999)
1999Sincock PM, Fitter S, Parton RG, Berndt MC, Gamble JR, Ashman LK, 'PETA-3/CD151, a member of the transmembrane 4 superfamily, is localised to the plasma membrane and endocytic system of endothelial cells, associates with multiple integrins and modulates cell function', JOURNAL OF CELL SCIENCE, 112 833-844 (1999)
1999Ashman LK, Ferrao P, Cole SR, Cambareri AC, 'Effects of mutant c-Kit in early myeloid cells', LEUKEMIA & LYMPHOMA, 34 451-461 (1999)
1998Yanez-Mo M, Alfranca A, Cabanas C, Marazuela M, Tejedor R, Ursa MA, et al., 'Regulation of endothelial cell motility by complexes of tetraspan molecules CD81/TAPA-1 and CD151/PETA-3 with alpha 3 beta 1 integrin localized at endothelial lateral junctions', JOURNAL OF CELL BIOLOGY, 141 791-804 (1998)
1998Caruana G, Cambareri AC, Gonda TJ, Ashman LK, 'Transformation of NIH3T3 fibroblasts by the c-Kit receptor tyrosine kinase: effect of receptor density and ligand-requirement', ONCOGENE, 16 179-190 (1998)
1998Afonja O, Amorosi E, Ashman L, Takeshita K, 'Multilineage involvement and erythropoietin-"independent" erythroid progenitor cells in a patient with systemic mastocytosis', ANNALS OF HEMATOLOGY, 77 183-186 (1998)
1998Fitter S, Seldin MF, Ashman LK, 'Characterisation of the mouse homologue of CD151 (PETA-3/SFA-1); genomic structure, chromosomal localisation and identification of 2 novel splice forms', BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1398 75-85 (1998)
1998Okayama Y, Kobayashi H, Ashman LK, Dobashi K, Nakazawa T, Holgate ST, et al., 'Human lung mast cells are enriched in the capacity to produce granulocyte-macrophage colony-stimulating factor in response to IgE-dependent stimulation', EUROPEAN JOURNAL OF IMMUNOLOGY, 28 708-715 (1998)
1997Ferrao P, Gonda TJ, Ashman LK, 'Expression of constitutively activated human c-Kit in myb transformed early myeloid cells leads to factor independence, histiocytic differentiation, and tumorigenicity', BLOOD, 90 4539-4552 (1997)
1997Sincock PM, Ashman LK, 'Expression of c-Kit and functional drug efflux are correlated in de novo acute myeloid leukaemia', LEUKEMIA, 11 1850-1857 (1997)
1997Zannettino ACW, Aylett GW, Leavesley DI, Pietsch T, Chang DG, Simmons PJ, Ashman LK, 'Specificity and functional effects of antibodies to human stem cell factor', GROWTH FACTORS, 14 67-79 (1997)
1997Atkins GJ, Qiao M, Coombe DR, Gowans EJ, Ashman LK, 'Hepatitis B virus binding to leucocyte plasma membranes utilizes a different region of the preS1 domain to the hepatocyte receptor binding site and does not require receptors for opsonins', IMMUNOLOGY AND CELL BIOLOGY, 75 259-266 (1997)
1997Sincock PM, Mayrhofer G, Ashman LK, 'Localization of the transmembrane 4 superfamily (TM4SF) member PETA-3 (CD151) in normal human tissues: Comparison with CD9, CD63, and alpha 5 beta 1 integrin', JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 45 515-525 (1997)
1996Baghestanian M, Agis H, Bevec D, Bankl HC, Hofbauer R, Kress HG, et al., 'Stem cell factor-induced downregulation of c-kit in human lung mast cells and HMC-1 mast cells', EXPERIMENTAL HEMATOLOGY, 24 1377-1386 (1996)
1996Gattei V, Aldinucci D, Quinn JMW, Degan M, Cozzi M, Perin V, et al., 'Human osteoclasts and preosteoclast cells (FLG 29.1) express functional c-kit receptors and interact with osteoblast and stromal cells via membrane-bound stem cell factor', CELL GROWTH & DIFFERENTIATION, 7 753-763 (1996)
1996Shimizu YJ, Ashman LK, Du ZM, Schwartz LB, 'Internalization of Kit together with stem cell factor on human fetal liver-derived mast cells - New protein and RNA synthesis is required for reappearance of Kit', JOURNAL OF IMMUNOLOGY, 156 3443-3449 (1996)
1996Geary SM, Ashman LK, 'HL-60 myeloid leukaemia cells acquire immunostimulatory capability upon treatment with retinoic acid: Analysis of the responding population and mechanism of cytotoxic lymphocyte activation', IMMUNOLOGY, 88 428-440 (1996)
1996Zannettino ACW, Rayner JR, Ashman LK, Gonda TJ, Simmons PJ, 'A powerful new technique for isolating genes encoding cell surface antigens using retroviral expression cloning', JOURNAL OF IMMUNOLOGY, 156 611-620 (1996)
1996Cole SR, Aylett GW, Casey G, Harvey NL, Cambareri AC, Ashman LK, 'Increased expression of c-Kit or its ligand Steel Factor is not a common feature of adult acute myeloid leukaemia', LEUKEMIA, 10 288-296 (1996)
1996Kurosawa K, Miyazawa K, Gotoh A, Katagiri T, Nishimaki J, Ashman LK, Toyama K, 'Immobilized anti-KIT monoclonal antibody induces ligand-independent dimerization and activation of steel factor receptor: Biologic similarity with membrane-bound form of steel factor rather than its soluble form', BLOOD, 87 2235-2243 (1996)
1995ROBERTS JJ, RODGERS SE, DRURY J, ASHMAN LK, LLOYD JV, 'PLATELET ACTIVATION-INDUCED BY A MURINE MONOCLONAL-ANTIBODY DIRECTED AGAINST A NOVEL TETRA-SPAN ANTIGEN', BRITISH JOURNAL OF HAEMATOLOGY, 89 853-860 (1995) [C1]
1995Ashman LK, Sincock PM, Cole SR, 'Functional drug efflux P-glycoprotein and c-Kit expression in acute myeloid leukemia.', BLOOD, 86 2048-2048 (1995)
1995SHIMIZU Y, ASHMAN L, SCHWARTZ LB, 'REGULATION OF KIT DURING STEM-CELL FACTOR (SCF)-DEPENDENT DEVELOPMENT OF FETAL LIVER-DERIVED HUMAN MAST-CELLS', FASEB JOURNAL, 9 A200-A200 (1995)
1995Gattei V, Aldinucci D, Quinn JMW, Degan M, Cozzi M, Perin V, et al., 'Human primary osteoclasts and preosteoclast cells (FLG 29.1) express functional c-kit receptors and interact with osteoblast and stromal cells via membrane-bound stem cell factor (mb-SCF)', BLOOD, 86 79-79 (1995)
1995FITTER S, TETAZ TJ, BERNDT MC, ASHMAN LK, 'MOLECULAR-CLONING OF CDNA-ENCODING A NOVEL PLATELET-ENDOTHELIAL CELL TETRA-SPAN ANTIGEN, PETA-3', BLOOD, 86 1348-1355 (1995)
1995KEES UR, ASHMAN LK, 'SYNERGISTIC ACTION OF INTERLEUKIN-2 AND STEEL FACTOR (SLF) ON A HUMAN T-LYMPHOBLASTOID CELL-LINE', LEUKEMIA, 9 1046-1050 (1995)
1995FERRAO P, MACMILLAN EM, ASHMAN LK, GONDA TJ, 'ENFORCED EXPRESSION OF FULL-LENGTH C-MYB LEADS TO DENSITY-DEPENDENT TRANSFORMATION OF MURINE HEMATOPOIETIC-CELLS', ONCOGENE, 11 1631-1638 (1995)
1995IRANI AA, NILSSON G, ASHMAN LK, SCHWARTZ LB, 'DEXAMETHASONE INHIBITS THE DEVELOPMENT OF MAST-CELLS FROM DISPERSED HUMAN FETAL LIVER-CELLS CULTURED IN THE PRESENCE OF RECOMBINANT HUMAN STEM-CELL FACTOR', IMMUNOLOGY, 84 72-78 (1995)
1995SHIMIZU Y, IRANI AMA, BROWN EJ, ASHMAN LK, SCHWARTZ LB, 'HUMAN MAST-CELLS DERIVED FROM FETAL LIVER-CELLS CULTURED WITH STEM-CELL FACTOR EXPRESS A FUNCTIONAL CD51/CD61 (ALPHA-V-BETA-3) INTEGRIN', BLOOD, 86 930-939 (1995)
1995ASHMAN LK, AYLETT GW, CAMBARERI AC, LEVESQUE JP, SIMMONS PJ, 'STEEL FACTOR AND ITS RECEPTOR C-KIT MEDIATE CELL-CELL INTERACTIONS', JOURNAL OF INVESTIGATIVE DERMATOLOGY, 105 2-2 (1995)
1995Zannettino ACW, Buhring HJ, Niutta S, Ashman LK, Kanz L, Simmons PJ, 'Identification and functional cloning of MGC-24, a mucin-like molecule expressed by haemopoietic progenitors and bone marrow stromal cells: A negative regulator of haemopoiesis', BLOOD, 86 2350-2350 (1995)
1994TO LB, HAYLOCK DN, DOWSE T, SIMMONS PJ, TRIMBOLI S, ASHMAN LK, JUTTNER CA, 'A COMPARATIVE-STUDY OF THE PHENOTYPE AND PROLIFERATIVE CAPACITY OF PERIPHERAL-BLOOD (PB) CD34(+) CELLS MOBILIZED BY 4 DIFFERENT PROTOCOLS AND THOSE OF STEADY-PHASE PB AND BONE-MARROW CD34(+) CELLS', BLOOD, 84 2930-2939 (1994)
1994NILSSON G, MIETTINEN U, ISHIZAKA T, ASHMAN LK, IRANI AM, SCHWARTZ LB, 'INTERLEUKIN-4 INHIBITS THE EXPRESSION OF KIT AND TRYPTASE DURING STEM-CELL FACTOR-DEPENDENT DEVELOPMENT OF HUMAN MAST-CELLS FROM FETAL LIVER-CELLS', BLOOD, 84 1519-1527 (1994)
1994ASHMAN LK, BUHRING HJ, AYLETT GW, BROUDY VC, MULLER C, 'EPITOPE MAPPING AND FUNCTIONAL-STUDIES WITH 3 MONOCLONAL-ANTIBODIES TO THE C-KIT RECEPTOR TYROSINE KINASE, YB5.B8, 17F11, AND SR-1', JOURNAL OF CELLULAR PHYSIOLOGY, 158 545-554 (1994)
1994KUROSAWA K, MIYAZAWA K, GOTOH A, NISHIMAKI J, ASHMAN LK, TOYAMA K, 'IMMOBILIZED YB5.B8 MONOCLONAL-ANTIBODY INDUCES LIGAND-INDEPENDENT DIMERIZATION AND ACTIVATION OF C-KIT ENCODED PROTEIN - BIOLOGICAL SIMILARITY WITH MEMBRANE-BOUND FORM OF STEEL FACTOR RATHER THAN ITS SOLUBLE FORM', BLOOD, 84 A123-A123 (1994)
1994SIMMONS PJ, AYLETT GW, NIUTTA S, TO LB, JUTTNER CA, ASHMAN LK, 'C-KIT IS EXPRESSED BY PRIMITIVE HUMAN HEMATOPOIETIC-CELLS THAT GIVE RISE TO COLONY-FORMING CELLS IN STROMA-DEPENDENT CYTOKINE-SUPPLEMENTED CULTURE', EXPERIMENTAL HEMATOLOGY, 22 157-165 (1994)
1994OKAYAMA Y, HUNT TC, KASSEL O, ASHMAN L, CHURCH MK, 'ASSESSMENT OF THE ANTI-C-KIT MONOCLONAL-ANTIBODY - YB5,B8 IN MAGNETIC AFFINITY ENRICHMENT OF HUMAN MAST-CELLS PREPARATIONS', CLINICAL AND EXPERIMENTAL ALLERGY, 24 179-179 (1994)
1994GRABBE J, WELKER P, MOLLER A, DIPPEL E, ASHMAN LK, CZARNETZKI BM, 'COMPARATIVE CYTOKINE RELEASE FROM HUMAN MONOCYTES, MONOCYTE-DERIVED IMMATURE MAST-CELLS, AND A HUMAN MAST-CELL LINE (HMC-1)', JOURNAL OF INVESTIGATIVE DERMATOLOGY, 103 504-508 (1994)
1994OKAYAMA Y, HUNT TC, KASSEL O, ASHMAN LK, CHURCH MK, 'ASSESSMENT OF THE ANTI-C-KIT MONOCLONAL-ANTIBODY YB5.B8 IN AFFINITY MAGNETIC ENRICHMENT OF HUMAN LUNG MAST-CELLS', JOURNAL OF IMMUNOLOGICAL METHODS, 169 153-161 (1994)
1994SIMMONS PJ, LEAVESLEY DI, LEVESQUE JP, SWART BW, HAYLOCK DN, TO LB, et al., 'THE MOBILIZATION OF PRIMITIVE HEMATOPOIETIC PROGENITORS INTO THE PERIPHERAL-BLOOD', STEM CELLS, 12 187-202 (1994)
1994ASHMAN LK, FITTER S, TETAZ T, BERNDT MC, 'MOLECULAR-CLONING OF CDNA-ENCODING A NOVEL PLATELET ENDOTHELIAL-CELL TETRASPAN ANTIGEN', BLOOD, 84 A243-A243 (1994)
1993TOHDA S, YANG GS, ASHMAN LK, MCCULLOCH EA, MINDEN MD, 'RELATIONSHIP BETWEEN C-KIT EXPRESSION AND PROLIFERATION IN ACUTE MYELOBLASTIC-LEUKEMIA CELL-LINES', JOURNAL OF CELLULAR PHYSIOLOGY, 154 410-418 (1993)
1993LLOYD JV, ROBERTS JJ, RODGERS SE, ASHMAN LK, 'PLATELET ACTIVATION BY THE MURINE MONOCLONAL ANTIBODY-14A2.H1', BLOOD, 82 A609-A609 (1993)
1993TO LB, HAYLOCK DN, DOWSE T, SIMMONS PJ, ASHMAN LK, JUTTNER CA, 'PHENOTYPE AND PROLIFERATIVE CAPACITY OF PERIPHERAL-BLOOD CD34+ CELLS MOBILIZED BY 4 DIFFERENT PROTOCOLS', BLOOD, 82 A493-A493 (1993)
1993TOHDA S, ASHMAN LK, MINDEN MD, 'THE ROLE OF STROMA CELLS ON THE PROLIFERATION AND C-KIT EXPRESSION OF ACUTE MYELOBLASTIC-LEUKEMIA CELLS', INTERNATIONAL JOURNAL OF ONCOLOGY, 3 1141-1147 (1993)
1993GEARY SM, ASHMAN LK, 'IMMUNOSTIMULATORY NATURE OF A HUMAN LEUKEMIC-CELL LINE, HL-60, AFTER TREATMENT WITH RETINOIC ACID', JOURNAL OF LEUKOCYTE BIOLOGY, 89-89 (1993)
1993ATKINS GJ, GOWANS EJ, ASHMAN LK, 'HEPATITIS-B VIRUS RECEPTORS ON HEMATOPOIETIC-CELLS', JOURNAL OF LEUKOCYTE BIOLOGY, 46-46 (1993)
1993FITTER S, BERNDT MC, ZANNETTINO ACW, ASHMAN LK, 'MOLECULAR-CLONING OF CDNA-ENCODING A NOVEL HUMAN PLATELET MEGAKARYOCYTE SURFACE-ANTIGEN', JOURNAL OF LEUKOCYTE BIOLOGY, 103-103 (1993)
1993ZANNETTINO ACW, RAYNER J, ASHMAN LK, GONDA TJ, SIMMONS PJ, 'USE OF A RETROVIRAL CDNA EXPRESSION LIBRARY TO CLONE GENES ENCODING NOVEL HUMAN STROMAL CELL ANTIGENS', JOURNAL OF LEUKOCYTE BIOLOGY, 103-103 (1993)
1993MAZE R, HORIE M, HENDRIE P, VADHANRAJ S, TRICOT G, GORDON M, et al., 'DIFFERENTIAL RESPONSES OF MYELOID PROGENITOR CELLS FROM PATIENTS WITH MYELOID-LEUKEMIA AND MYELODYSPLASIA TO THE COSTIMULATING EFFECTS OF STEEL FACTOR IN-VITRO', EXPERIMENTAL HEMATOLOGY, 21 545-551 (1993)
1993MATOS ME, SCHNIER GS, BEECHER MS, ASHMAN LK, WILLIAMS DE, CALIGIURI MA, 'EXPRESSION OF A FUNCTIONAL C-KIT RECEPTOR ON A SUBSET OF NATURAL-KILLER-CELLS', JOURNAL OF EXPERIMENTAL MEDICINE, 178 1079-1084 (1993)
1993NILSSON G, FORSBERG K, BODGER MP, ASHMAN LK, ZSEBO KM, ISHIZAKA T, et al., 'PHENOTYPIC CHARACTERIZATION OF STEM-CELL FACTOR-DEPENDENT HUMAN FETAL LIVER-DERIVED MAST-CELLS', IMMUNOLOGY, 79 325-330 (1993)
1993ASANO Y, BRACH MA, AHLERS A, DEVOS S, BUTTERFIELD JH, ASHMAN LK, et al., 'PHORBOL ESTER 12-O-TETRADECANOYLPHORBOL-13-ACETATE DOWN-REGULATES EXPRESSION OF THE C-KIT PROTOONCOGENE PRODUCT', JOURNAL OF IMMUNOLOGY, 151 2345-2354 (1993)
1993CARUANA G, ASHMAN LK, FUJITA J, GONDA TJ, 'RESPONSES OF THE MURINE MYELOID CELL-LINE FDC-P1 TO SOLUBLE AND MEMBRANE-BOUND FORMS OF STEEL FACTOR (SLF)', EXPERIMENTAL HEMATOLOGY, 21 761-768 (1993)
1993FURITSU T, TSUJIMURA T, TONO T, IKEDA H, KITAYAMA H, KOSHIMIZU U, et al., 'IDENTIFICATION OF MUTATIONS IN THE CODING SEQUENCE OF THE PROTOONCOGENE C-KIT IN A HUMAN MAST-CELL LEUKEMIA-CELL LINE CAUSING LIGAND-INDEPENDENT ACTIVATION OF C-KIT PRODUCT', JOURNAL OF CLINICAL INVESTIGATION, 92 1736-1744 (1993)
1992CICUTTINI FM, MARTIN M, SALVARIS E, ASHMAN L, BEGLEY CG, NOVOTNY J, et al., 'SUPPORT OF HUMAN CORD BLOOD PROGENITOR CELLS ON HUMAN STROMAL CELL-LINES TRANSFORMED BY SV(40) LARGE T-ANTIGEN UNDER THE INFLUENCE OF AN INDUCIBLE (METALLOTHIONEIN) PROMOTER', BLOOD, 80 102-112 (1992)
1992IRANI AMA, NILSSON G, MIETTINEN U, CRAIG SS, ASHMAN LK, ISHIZAKA T, et al., 'RECOMBINANT HUMAN STEM-CELL FACTOR STIMULATES DIFFERENTIATION OF MAST-CELLS FROM DISPERSED HUMAN FETAL LIVER-CELLS', BLOOD, 80 3009-3021 (1992)
1992MAZE R, HORIE M, HENDRIE PC, VADHANRAJ S, TRICOT G, ASHMAN LK, BROXMEYER HE, 'HETEROGENEOUS RESPONSIVENESS INVITRO OF MYELOID PROGENITOR CELLS FROM PATIENTS WITH MYELOID-LEUKEMIA TO THE CO-STIMULATING EFFECTS OF STEEL FACTOR', EXPERIMENTAL HEMATOLOGY, 20 761-761 (1992)
1992SIMMONS PJ, NIUTTA S, ASHMAN LK, BERNDT MC, JUTTNER CA, 'PRIMITIVE HUMAN BONE-MARROW PROGENITORS EXPRESS L-SELECTIN AND PECAM-1(CD31)', EXPERIMENTAL HEMATOLOGY, 20 829-829 (1992)
1992HUNT TC, HEUSSER C, MUELLER R, BULLOCK G, OKAYAMA Y, ASHMAN LK, CHURCH MK, 'HUMAN LUNG MAST-CELLS PRODUCE INTERLEUKIN-4', JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 89 245-245 (1992)
1992BRACH MA, BUHRING HJ, GRUSS HJ, ASHMAN LK, LUDWIG WD, MERTELSMANN RH, HERRMANN F, 'FUNCTIONAL EXPRESSION OF C-KIT BY ACUTE MYELOGENOUS LEUKEMIA BLASTS IS ENHANCED BY TUMOR-NECROSIS-FACTOR-ALPHA THROUGH POSTTRANSCRIPTIONAL MESSENGER-RNA STABILIZATION BY A LABILE PROTEIN (RETRACTED ARTICLE. SEE VOL 93, PG. 3573, 1999)', BLOOD, 80 1224-1230 (1992)
1992JACOBSON MR, BENTLEY AM, CUMBERWORTH V, SCHWARTZ LB, IRANI AM, ASHMAN LK, et al., 'IMMUNOHISTOLOGY OF THE NASAL-MUCOSA IN SEASONAL ALLERGIC RHINITIS - INCREASES IN ACTIVATED EOSINOPHILS AND EPITHELIAL MAST-CELLS', JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 89 216-216 (1992)
1991MIYAZAWA K, HENDRIE PC, MANTEL C, WOOD K, ASHMAN LK, BROXMEYER HE, 'COMPARATIVE-ANALYSIS OF SIGNALING PATHWAYS BETWEEN MAST-CELL GROWTH-FACTOR (C-KIT LIGAND) AND GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR IN A HUMAN FACTOR-DEPENDENT MYELOID CELL-LINE INVOLVES PHOSPHORYLATION OF RAF-1, GTPASE-ACTIVATING PROTEIN AND MITOGEN-ACTIVATED PROTEIN-KINASE', EXPERIMENTAL HEMATOLOGY, 19 1110-1123 (1991)
1991ASHMAN LK, CAMBARERI AC, TO LB, LEVINSKY RJ, JUTTNER CA, 'EXPRESSION OF THE YB5.B8 ANTIGEN (C-KIT PROTOONCOGENE PRODUCT) IN NORMAL HUMAN BONE-MARROW', BLOOD, 78 30-37 (1991)
1991LERNER NB, NOCKA KH, COLE S, QIU FH, STRIFE A, ASHMAN LK, BESMER P, 'MONOCLONAL ANTIBODY-YB5.B8 IDENTIFIES THE HUMAN C-KIT PROTEIN PRODUCT', BLOOD, 77 1876-1883 (1991)
1991ASHMAN LK, AYLETT GW, 'EXPRESSION OF CD31-EPITOPES ON HUMAN-LYMPHOCYTES - CD31-MONOCLONAL ANTIBODIES DIFFERENTIATE BETWEEN NAIVE (CD45RA+) AND MEMORY (CD45RA-) CD4-POSITIVE T-CELLS', TISSUE ANTIGENS, 38 208-212 (1991)
1991ASHMAN LK, AYLETT GW, MEHRABANI PA, BENDALL LJ, NIUTTA S, CAMBARERI AC, et al., 'THE MURINE MONOCLONAL-ANTIBODY, 14A2.H1, IDENTIFIES A NOVEL PLATELET SURFACE-ANTIGEN', BRITISH JOURNAL OF HAEMATOLOGY, 79 263-270 (1991)
1991ASHMAN LK, AYLETT GW, CAMBARERI AC, COLE S, 'DIFFERENT EPITOPES OF THE CD31 ANTIGEN IDENTIFIED BY MONOCLONAL-ANTIBODIES - CELL TYPE-SPECIFIC PATTERNS OF EXPRESSION', TISSUE ANTIGENS, 38 199-207 (1991)
1991SILLABER C, STROBL H, BEVEC D, ASHMAN LK, BUTTERFIELD JH, LECHNER K, et al., 'IL-4 REGULATES C-KIT PROTOONCOGENE PRODUCT EXPRESSION IN HUMAN MAST AND MYELOID PROGENITOR CELLS', JOURNAL OF IMMUNOLOGY, 147 4224-4228 (1991)
1990ASHMAN LK, CAMBARERI AC, EGLINTON JM, 'A MONOCLONAL-ANTIBODY THAT INHIBITS THE ACTION OF GM-CSF ON NORMAL BUT NOT LEUKEMIC PROGENITORS', LEUKEMIA RESEARCH, 14 637-644 (1990)
1989COLE S, KRIEK GW, HOPE RM, ASHMAN LK, 'TRANSFECTION OF GENES FOR HUMAN CELL-SURFACE ANTIGENS IDENTIFIED BY MONOCLONAL-ANTIBODIES', IMMUNOLOGY AND CELL BIOLOGY, 67 377-384 (1989)
1989VALENT P, ASHMAN LK, HINTERBERGER W, ECKERSBERGER F, MAJDIC O, LECHNER K, BETTELHEIM P, 'MAST-CELL TYPING - DEMONSTRATION OF A DISTINCT HEMATOPOIETIC-CELL TYPE AND EVIDENCE FOR IMMUNOPHENOTYPIC RELATIONSHIP TO MONONUCLEAR PHAGOCYTES', BLOOD, 73 1778-1785 (1989)
1988ASHMAN LK, ROBERTS MM, GADD SJ, COOPER SJ, JUTTNER CA, 'EXPRESSION OF A 150-KD CELL-SURFACE ANTIGEN IDENTIFIED BY MONOCLONAL-ANTIBODY YB5.B8 IS ASSOCIATED WITH POOR PROGNOSIS IN ACUTE NON-LYMPHOBLASTIC LEUKEMIA', LEUKEMIA RESEARCH, 12 923-928 (1988)
1988LYONS AB, ASHMAN LK, 'THE EFFECT OF RECOMBINANT CYTOKINES ON THE PROLIFERATIVE POTENTIAL AND PHENOTYPE OF CELLS OF THE HUMAN MYELOMONOCYTIC LEUKEMIA LINE, RC-2A', LEUKEMIA RESEARCH, 12 659-666 (1988)
1988LYONS AB, COOPER SJ, COLE S, ASHMAN LK, 'HUMAN MYELOID DIFFERENTIATION ANTIGENS IDENTIFIED BY MONOCLONAL-ANTIBODIES TO THE MYELOMONOCYTIC LEUKEMIA-CELL LINE RC-2A', PATHOLOGY, 20 137-146 (1988)
1988CAMBARERI AC, ASHMAN LK, COLE S, LYONS AB, 'A MONOCLONAL-ANTIBODY TO A HUMAN MAST-CELL MYELOID LEUKEMIA-SPECIFIC ANTIGEN BINDS TO NORMAL HEMATOPOIETIC PROGENITOR CELLS AND INHIBITS COLONY FORMATION INVITRO', LEUKEMIA RESEARCH, 12 929-& (1988)
1987COLE S, ASHMAN LK, EY PL, 'BIOTINYLATION - AN ALTERNATIVE TO RADIOIODINATION FOR THE IDENTIFICATION OF CELL-SURFACE ANTIGENS IN IMMUNOPRECIPITATES', MOLECULAR IMMUNOLOGY, 24 699-705 (1987)
1987ASHMAN LK, WHITE D, ZOLA H, DART GW, 'EXPRESSION OF THE NON-T ALL-ASSOCIATED P24 ANTIGEN ON LEUKEMIC BLASTS FROM PATIENTS WITH ANLL', LEUKEMIA RESEARCH, 11 97-& (1987)
1987ASHMAN LK, 'THE IMMUNOGENICITY OF TUMOR-CELLS', IMMUNOLOGY AND CELL BIOLOGY, 65 271-277 (1987)
1987VALENT P, STAIN C, ASHMAN LK, BRANTSCHEN S, STADLER BM, HINTERBERGER W, et al., 'THE PHENOTYPE OF HUMAN CONNECTIVE-TISSUE TYPE (CTMC) AND MUCOSAL MAST-CELLS (MMC)', BLUT, 55 360-360 (1987)
1987ASHMAN LK, KRIEK GW, COOPER SJ, OKEEFE DE, 'REQUIREMENTS FOR THE STIMULATION OF ALLOGENEIC LYMPHOCYTES-T BY ACUTE NONLYMPHOBLASTIC LEUKEMIA-CELLS', CANCER IMMUNOLOGY IMMUNOTHERAPY, 25 250-256 (1987)
1987MAYRHOFER G, GADD SJ, SPARGO LDJ, ASHMAN LK, 'SPECIFICITY OF A MOUSE MONOCLONAL-ANTIBODY RAISED AGAINST ACUTE MYELOID-LEUKEMIA CELLS FOR MAST-CELLS IN HUMAN MUCOSAL AND CONNECTIVE TISSUES', IMMUNOLOGY AND CELL BIOLOGY, 65 241-250 (1987)
1987WHITE DL, ASHMAN LK, DART GW, ZOLA H, TOOGOOD IRG, KIMBER RJ, 'THE EXPRESSION OF MATURE MYELOID CELL-DIFFERENTIATION MARKERS IN ACUTE-LEUKEMIA', PATHOLOGY, 19 137-142 (1987)
1987ASHMAN LK, DREW PA, TOOGOOD IRG, JUTTNER CA, 'IMMUNOLOGICAL COMPETENCE OF PATIENTS IN REMISSION FROM ACUTE-LEUKEMIA - APPARENTLY NORMAL T-CELL FUNCTION BUT DEFECTIVE POKEWEED MITOGEN-DRIVEN IMMUNOGLOBULIN-SYNTHESIS', IMMUNOLOGY AND CELL BIOLOGY, 65 201-210 (1987)
1987LYONS AB, ASHMAN LK, 'STUDIES ON THE DIFFERENTIATION OF THE HUMAN MYELOMONOCYTIC CELL-LINE RC-2A IN RESPONSE TO LYMPHOCYTE-DERIVED FACTORS', LEUKEMIA RESEARCH, 11 797-& (1987)
1987ASHMAN L, ROBERTS M, GADD S, COOPER S, JUTTNER C, 'A SUBGROUP OF ANLL WITH POOR RESPONSE TO STANDARD CHEMOTHERAPY IDENTIFIED BY A MONOCLONAL-ANTIBODY', MEDICAL AND PEDIATRIC ONCOLOGY, 15 152-152 (1987)
1986EY PL, ASHMAN LK, 'THE USE OF ALKALINE PHOSPHATASE-CONJUGATED ANTIIMMUNOGLOBULIN WITH IMMUNOBLOTS FOR DETERMINING THE SPECIFICITY OF MONOCLONAL-ANTIBODIES TO PROTEIN MIXTURES', METHODS IN ENZYMOLOGY, 121 497-509 (1986)
1986WHITE DL, ASHMAN LK, DART GW, ZOLA H, KIMBER RJ, 'THE SELECTION OF A PANEL OF LOCALLY PRODUCED MONOCLONAL-ANTIBODIES FOR THE CLASSIFICATION OF ACUTE LEUKEMIAS', AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 16 124-124 (1986)
1986ASHMAN LK, OKEEFE DE, JUTTNER CA, TOOGOOD IRG, RICE MS, 'AUTOLOGOUS RESPONSES TO HUMAN-LEUKEMIC CELLS IN MIXED LEUKOCYTE-CULTURE', CANCER IMMUNOLOGY IMMUNOTHERAPY, 22 95-99 (1986)
1985LYONS AB, ASHMAN LK, 'THE ROSE-BENGAL ASSAY FOR MONOCLONAL-ANTIBODIES TO CELL-SURFACE ANTIGENS - COMPARISONS WITH COMMON HYBRIDOMA SCREENING METHODS', JOURNAL OF IMMUNOASSAY, 6 325-345 (1985)
1985ASHMAN LK, GESCHE AH, 'SURFACE-ANTIGEN EXPRESSION BY A HUMAN B-LYMPHOBLASTOID CELL-LINE TREATED WITH DIFFERENTIATION INDUCERS, DIMETHYSULFOXIDE AND TETRADECANOYLPHORBOL ACETATE', LEUKEMIA RESEARCH, 9 157-& (1985)
1985GADD SJ, BROGAN MP, ASHMAN LK, 'SPECIFICITY OF THE PASSIVE ANTIBODY-INDUCED SUPPRESSION OF THE HUMORAL IMMUNE-RESPONSE OF MICE TO SURFACE-ANTIGENS ON HUMAN-CELLS', IMMUNOLOGY, 54 223-231 (1985)
1985GESCHE AH, ASHMAN LK, 'VARIATIONS IN ANTIGEN EXPRESSION DURING THE CELL-CYCLE OF A HUMAN B-LYMPHOBLASTOID CELL-LINE', LEUKEMIA RESEARCH, 9 147-& (1985)
1985GADD SJ, ASHMAN LK, 'A MURINE MONOCLONAL-ANTIBODY SPECIFIC FOR A CELL-SURFACE ANTIGEN EXPRESSED BY A SUBGROUP OF HUMAN MYELOID LEUKEMIAS', LEUKEMIA RESEARCH, 9 1329-1336 (1985)
1984ASHMAN LK, 'PROLIFERATIVE RESPONSE OF NORMAL AND ACTIVATED HUMAN-LYMPHOCYTES TO TETRADECANOYL PHORBOL ACETATE', CELLULAR IMMUNOLOGY, 87 613-625 (1984)
1983GADD SJ, ASHMAN LK, 'BINDING OF MOUSE MONOCLONAL-ANTIBODIES TO HUMAN-LEUKEMIC CELLS VIA THE FC RECEPTOR - A POSSIBLE SOURCE OF FALSE POSITIVE REACTIONS IN SPECIFICITY SCREENING', CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 54 811-818 (1983)
1983ASHMAN LK, 'IMMUNE-RESPONSES TO HUMAN-LEUKEMIC CELLS-INVITRO', MEDICAL AND PEDIATRIC ONCOLOGY, 11 197-197 (1983)
1983ASHMAN LK, 'STIMULATORY ABILITY OF HUMAN-LEUKEMIC CELLS IN THE ALLOGENEIC MIXED LEUKOCYTE REACTION', AUSTRALIAN JOURNAL OF EXPERIMENTAL BIOLOGY AND MEDICAL SCIENCE, 61 477-488 (1983)
1982OKEEFE D, ASHMAN L, 'VARIATION IN ACCESSORY CELL REQUIREMENTS IN HUMAN MIXED LYMPHOCYTE-RESPONSE TO LEUKEMIC-CELL LINES', IMMUNOLOGY, 47 633-641 (1982)
1982OKEEFE D, ASHMAN L, 'PEANUT AGGLUTININ - A MARKER FOR NORMAL AND LEUKEMIC-CELLS OF THE MONOCYTE LINEAGE', CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 48 329-338 (1982)
1982ASHMAN LK, MURRAY AW, COOK MG, KOTLARSKI I, '2-STAGE SKIN CARCINOGENESIS IN SENSITIVE AND RESISTANT MOUSE STRAINS', CARCINOGENESIS, 3 99-102 (1982)
1982OCONNOR CG, ASHMAN LK, 'APPLICATION OF THE NITROCELLULOSE TRANSFER TECHNIQUE AND ALKALINE-PHOSPHATASE CONJUGATED ANTI-IMMUNOGLOBULIN FOR DETERMINATION OF THE SPECIFICITY OF MONOCLONAL-ANTIBODIES TO PROTEIN MIXTURES', JOURNAL OF IMMUNOLOGICAL METHODS, 54 267-271 (1982)
1980ASHMAN LK, GOH DHB, KOTLARSKI I, 'INVOLVEMENT OF DONOR LYMPHORETICULAR CELLS IN THE REJECTION OF B-16 MELANOMA BY ALLOGENEIC MICE', AUSTRALIAN JOURNAL OF EXPERIMENTAL BIOLOGY AND MEDICAL SCIENCE, 58 159-166 (1980)
1980VINGELIS V, ASHMAN LK, KOTLARSKI I, 'FACTORS AFFECTING THE ABILITY OF VARIOUS STRAINS OF ENTEROBACTERIACEAE TO INDUCE TUMOR RESISTANCE IN MICE', AUSTRALIAN JOURNAL OF EXPERIMENTAL BIOLOGY AND MEDICAL SCIENCE, 58 123-131 (1980)
1980DEYOUNG NJ, ASHMAN LK, LUDBROOK J, MARSHALL VR, 'COMPARISON OF 3 BLOOD-TESTS FOR CANCER', SURGERY GYNECOLOGY & OBSTETRICS, 150 12-16 (1980)
1979ASHMAN LK, COOK MG, KOTLARSKI I, 'PROTECTIVE EFFECT OF ORAL SALMONELLA-ENTERITIDIS 11RX INFECTION AGAINST COLON-TUMOR INDUCTION BY 1,2-DIMETHYLHYDRAZINE IN MICE', CANCER RESEARCH, 39 2768-2771 (1979)
1979DEYOUNG NJ, ASHMAN LK, LUDBROOK J, MARSHALL VR, 'CANCER DISCRIMINATORY ABILITY OF THE CARCINOEMBRYONIC ANTIGEN-ASSAY, PHOSPHOHEXOSE ISOMERASE ACTIVITY AND ERYTHROCYTE SEDIMENTATION-RATE', AUSTRALIAN AND NEW ZEALAND JOURNAL OF SURGERY, 49 145-146 (1979)
1979ASHMAN LK, KOTLARSKI I, 'INHIBITION OF THE GROWTH OF LEWIS LUNG-CARCINOMA IN SYNGENEIC MICE BY SALMONELLA ANTIGENS', AUSTRALIAN JOURNAL OF EXPERIMENTAL BIOLOGY AND MEDICAL SCIENCE, 57 637-639 (1979)
1978DEYOUNG NJ, ASHMAN LK, 'PHYSICOCHEMICAL AND IMMUNOCHEMICAL PROPERTIES OF CARCINOEMBRYONIC ANTIGEN (CEA) FROM DIFFERENT TUMOR SOURCES', AUSTRALIAN JOURNAL OF EXPERIMENTAL BIOLOGY AND MEDICAL SCIENCE, 56 321-331 (1978)
1978ASHMAN LK, KOTLARSKI I, 'EFFECT OF SALMONELLA-ENTERITIDIS 11RX INFECTION ON 2-STAGE SKIN CARCINOGENESIS IN MICE', AUSTRALIAN JOURNAL OF EXPERIMENTAL BIOLOGY AND MEDICAL SCIENCE, 56 695-701 (1978)
1977ASHMAN LK, DEYOUNG NJ, 'IMMUNOADSORBENT PURIFICATION OF CARCINOEMBRYONIC ANTIGEN', IMMUNOCHEMISTRY, 14 329-336 (1977)
1977ASHMAN LK, LUDBROOK J, MARSHALL VR, 'COMPARISON OF WHOLE PLASMA AND PERCHLORIC ACID-EXTRACTED PLASMA ASSAYS FOR CARCINOEMBRYONIC ANTIGEN', CLINICA CHIMICA ACTA, 74 77-84 (1977)
1975ASHMAN LK, DEYOUNG NJ, GEARY D, LUDBROOK J, 'CARCINOEMBRYONIC ANTIGEN LEVELS IN PLASMA OF CANCER-PATIENTS AND OF CANCER-FREE HOSPITAL INPATIENTS', AUSTRALIAN AND NEW ZEALAND JOURNAL OF SURGERY, 45 109-109 (1975)
1975ASHMAN LK, KEECH DB, 'SHEEP KIDNEY PYRUVATE-CARBOXYLASE - STUDIES ON COUPLING OF ADENOSINE-TRIPHOSPHATE HYDROLYSIS AND CO2 FIXATION', JOURNAL OF BIOLOGICAL CHEMISTRY, 250 14-21 (1975)
1975ASHMAN LK, LUDBROOK J, MARSHALL VR, 'PROBABILISTIC APPLICATION OF PLASMA CARCINOEMBRYONIC ANTIGEN ASSAY IN CANCER-PATIENTS', BRITISH MEDICAL JOURNAL, 2 721-724 (1975)
1975ASHMAN LK, 'PURIFICATION OF CARCINOEMBRYONIC ANTIGEN BY AFFINITY CHROMATOGRAPHY USING IMMOBILIZED ANTIBODIES', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2 82-82 (1975)
1975ASHMAN LK, DEYOUNG NJ, 'IMMUNOADSORBENT PURIFICATION OF A GLYCOPROTEIN FROM HUMAN TUMOR TISSUE', PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY, 8 40-40 (1975)
1975ASHMAN LK, KEECH DB, 'KINETIC APPROACH TO DEFINING ROLE OF CHEMICALLY MODIFIABLE RESIDUES AT ACTIVE-SITES OF ENZYMES', AUSTRALIAN JOURNAL OF BIOLOGICAL SCIENCES, 28 379-387 (1975)
1974ASHMAN LK, KEECH DB, 'ANALOG STUDIES OF PYRUVATE-CARBOXYLASE REACTION-MECHANISM', PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY, 7 18-18 (1974)
1973ASHMAN LK, KEECH DB, 'DESENSITIZATION OF ALLOSTERIC ACTIVATION OF PYRUVATE CARBOXYLASE', PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY, 6 12-12 (1973)
1973ASHMAN LK, WALLACE JC, KEECH DB, 'DESENSITIZATION OF PYRUVATE CARBOXYLASE AGAINST ACETYL COA STIMULATION BY CHEMICAL MODIFICATION', BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 51 924-931 (1973)
1972ASHMAN LK, ATWELL JL, 'AMP DEAMINASE FROM RABBIT SKELETAL-MUSCLE - EFFECT OF MONOVALENT CATIONS ON CATALYTIC ACTIVITY AND MOLECULAR-WEIGHT', BIOCHIMICA ET BIOPHYSICA ACTA, 258 618-& (1972)
1972ASHMAN LK, WALLACE JC, KEECH DB, NIELSEN J, 'SHEEP KIDNEY PYRUVATE CARBOXYLASE - STUDIES ON ITS ACTIVATION BY ACETYL COENZYME-A AND CHARACTERISTICS OF ITS ACETYL COENZYME-A INDEPENDENT REACTION', JOURNAL OF BIOLOGICAL CHEMISTRY, 247 5818-& (1972)
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Conference (24 outputs)

YearCitationAltmetricsLink
2013Weidenhofer J, Bond D, Copeland B, Ashman L, 'Tetraspanin protein turnover rates vary in prostate cancer cell lines', BJU INTERNATIONAL (2013) [E3]
2013Copeland B, Ashman L, 'Tetraspanins as potential biomarkers in prostate cancer', BJU INTERNATIONAL (2013) [E3]
2013Bond D, Cairns M, Ashman L, Weidenhofer J, 'Post-transcriptional regulation of CD151 & CD9 by miRNAs in prostate cancer', BJU INTERNATIONAL (2013) [E3]
2012Bond DR, Cairns MJ, Ashman LK, Weidenhofer JC, 'Investigating micro-RNA regulation of tetraspanins CD151 and CD9 in prostate cancer', Febs Journal, Seville, Spain (2012) [E3]
2011Naudin C, Weidenhofer JC, Scott R, Ashman LK, Roselli SM, 'Induction of mindin expression is associated with glomerular basement membrane damage in Cd151(-/-) mice', Nephrology, Adelaide, SA (2011) [E3]
2011Vilain R, Braye SG, Ashman LK, Scott R, 'BRAF and NRAS mutational status are prognostically important in thick and locally advanced cutaneous melanoma', Pigment Cell & Melanoma Research, Tampa, FL (2011) [E3]

Co-authors: Rodney Scott

2011Mashkani B, Ashman LK, Griffith R, 'Implication of molecular docking in the study of structure-activity relationship of receptor tyrosine kinases inhibitors', Clinical Biochemistry, Mashhad, Iran (2011) [E3]
2010Vilain RE, Braye SG, Ashman LK, Scott R, 'Characterisation of KIT mutated melanomas: A step in the development of patient-tailored treatement for melanoma', Sydney Cancer Conference 2010. Profiling Risk, Personalising Treatment and Predicting Outcomes. Conference Program and Abstract Book, Sydney, NSW (2010) [E3]

Co-authors: Rodney Scott

2010Copeland BT, Vilain RE, Ashman LK, 'Biomarkers and regulatory proteins in prostate cancer', Sydney Cancer Conference 2010. Profiling Risk, Personalising Treatment and Predicting Outcomes. Conference Program and Abstract Book, Sydney, NSW (2010) [E3]
2010Verrills NM, Roberts KG, Smith AM, McDougall FK, Carpenter HC, Neviani P, et al., 'Targeting the tumour suppressor, PP2A, as a novel therapy for acute myeloid leukaemia', Sydney Cancer Conference 2010. Profiling Risk, Personalising Treatment and Predicting Outcomes. Conference Program and Abstract Book, Sydney, NSW (2010) [E3]
2010Vilain RE, Ashton KA, Bowden NA, Braye SG, Ashman LK, Scott RJ, 'Clinicopathological and gene expression profiling of advanced melanoma harbouring KIT and common kinase mutations', Melanoma 2010 Congress. Oral and Poster Abstracts, Sydney, NSW (2010) [E3]
2008Mashkani B, Kim K-T, Griffith R, Ashman LK, 'Different behaviour of FDC-P1 cells expressing different FLT3 activating mutations', HMRI Conference on Translational Cancer Research Abstracts, Newcastle, NSW (2008) [E3]
2008Baleato RM, Guthrie PL, Gubler M-C, Ashman LK, Roselli S, 'CD151-DEFICIENT MICE DEVELOP A STRAIN-DEPENDENT KIDNEY DISEASE DUE TO ALTERATIONS OF THE GLOMERULAR BASEMENT MEMBRANE', NEPHROLOGY (2008) [E3]
2007Roberts KG, Ashman LK, Sim AT, Verrills NM, 'Regulation of protein phosphatase 2A (PP2A) B subunits by Bcr/Abl: Potential targets for chronic myeloid leukemia', AACR Meeting Abstracts Online (Abstracts of the 98th AACR Annual Meeting), Los Angeles (2007) [E3]
2007Roberts KG, Ashman LK, Sim ATR, Verrills NM, 'Altered expression of PP2A regulatory subunits in chronic myelogenous leukemia: Identifying targets for improved therapies', BLOOD, Atlanta, GA (2007)
2005Foster R, Byrnes E, Ferrao P, Meldrum C, Ross G, Upjohn E, et al., 'A polymorphism in the transmembrane domain of c-KIT associated with pediatric mastocytosis', JOURNAL OF INVESTIGATIVE DERMATOLOGY, Perth, AUSTRALIA (2005)
2005Cowin AJ, Geary SM, Adams D, Wright MD, Ashman LK, 'Epidermal wound healing is defective in mice lacking tetraspanin CD151', JOURNAL OF INVESTIGATIVE DERMATOLOGY, Perth, AUSTRALIA (2005)
2004Griffith R, Foster RC, Brown MN, Ashman LK, 'Design of inhibitors of the KIT receptor tyrosine kinase', EuroQSAR 2004 Proceedings, Instanbul, Turkey (2004) [E1]
2004Foster RC, Griffith R, Ferrao PT, Ashman LK, 'Molecular Modelling of c-Kit Kinase Domains', MM2004: 9th Molecular Modelling Workshop, Sydney, Australia (2004) [E3]
2004Geary SM, Cowin A, Fitter S, Wright MD, Ashman LK, 'Defective in vitro epidermal wound healing in mice lacking the tetraspanin CD151', JOURNAL OF INVESTIGATIVE DERMATOLOGY, Nice, FRANCE (2004)
2003Ashman LK, Ferrao PT, Foster RC, Griffith R, 'Analysis of the Structure of the Kinase Domain of the Stem Cell Factor Receptor Tyrosin Kinase (c-Kit) - Constitutive Activation by a D816V Mutation and Inhibition by STI571', Fifth AFMC International Medicinal Chemistry Symposium AIMECS 03, Kyoto, Japan (2003) [E3]
1997Okayama Y, Kobayashi H, Ashman LK, Holgate ST, Church MK, Mori M, 'Activation of eosinophils with cytokines produced by lung mast cells', INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, TOKYO, JAPAN (1997)
1995Laver JH, Abboud MR, Kawashima I, Leary AG, Ashman LK, Ogawa M, 'Characterization of c-kit expression by primitive hematopoietic progenitors in umbilical cord blood', EXPERIMENTAL HEMATOLOGY, DUSSELDORF, GERMANY (1995)
1994KANAKURA Y, FURITSU T, TSUJIMURA T, BUTTERFIELD JH, ASHMAN LK, IKEDA H, et al., 'ACTIVATING MUTATIONS OF THE C-KIT PROTOONCOGENE IN A HUMAN MAST-CELL LEUKEMIA-CELL LINE', LEUKEMIA, MONTREAL, CANADA (1994)
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Grants and Funding

Summary

Number of grants66
Total funding$12,425,447

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Click on a grant title below to expand the full details for that specific grant.

2013 (1 grants)

Ultra-Low Temperature Cryogenic Freezer$24,596
Funding Body: NHMRC (National Health & Medical Research Council)

2012 (4 grants)

The Hunter Cancer Biobank (HCB): Maximising community value through validation, annotation and distribution throughout NSW$292,300
Funding Body: Cancer Institute NSW

Project Team
Professor John Forbes, Conjoint Professor Stephen Ackland, Professor Rodney Scott, Conjoint Associate Professor Barbara Young, Professor Hubert Hondermarck, Emeritus Professor Leonie Ashman, Professor Xu Dong Zhang, Doctor Kelly Kiejda, Doctor Nikki Verrills, Doctor Jennette Sakoff, Ms Janine Lombard, Doctor Jude Weidenhofer, Doctor Pradeep Tanwar
SchemeRole
Infrastructure GrantsInvestigator
Total AmountFunding StartFunding Finish
$292,30020122014
GNo:G1200798

High-Resolution Isoelectric Phosphoprotein Signalling System for Signalling Research, Biomarker Validation and Drug Development – Equipment Grant$143,394
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Rick Thorne, Professor Xu Dong Zhang, Professor Hubert Hondermarck, Conjoint Professor Stephen Ackland, Doctor Lisa Lincz, Doctor Jennette Sakoff, Emeritus Professor Leonie Ashman
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$143,39420122012
GNo:G1200555

Microscopic illumination system for advanced fluorescent protein technology$34,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Rick Thorne, Professor Xu Dong Zhang, Conjoint Associate Professor Murray Cairns, Doctor Nikki Verrills, Doctor Charles De Bock, Doctor Jude Weidenhofer, Doctor Severine Roselli, Doctor Kathryn Skelding, Emeritus Professor Leonie Ashman, Professor Hubert Hondermarck
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$34,00020122012
GNo:G1100983

Does Ubiquitination control the altered expression of tetraspanin proteins in Breast Cancer?$25,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Jude Weidenhofer, Emeritus Professor Leonie Ashman, Professor Hubert Hondermarck
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$25,00020122012
GNo:G1200169

2011 (3 grants)

Hunter Translational Cancer Research Unit$1,693,333
Funding Body: Cancer Institute NSW

Project Team
Conjoint Professor Stephen Ackland, Emeritus Professor Leonie Ashman, Professor John Forbes, Laureate Professor Robert Sanson-Fisher, Conjoint Associate Professor Anthony Proietto, Professor Rodney Scott
SchemeRole
Translational Cancer Research UnitInvestigator
Total AmountFunding StartFunding Finish
$1,693,33320112014
GNo:G1100545

Identifying the mechanisms underlying altered expression and mode of action of tetraspanins CD151 and CD9 in metastasis: progression to targeted treatment for prostate cancer$375,000
Funding Body: Prostate Cancer Foundation of Australia

Project Team
Emeritus Professor Leonie Ashman, Doctor Jude Weidenhofer
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$375,00020112013
GNo:G1000863

Investigation of the function of CD151 in the glomerular filtration barrier and identification of genetic modifiers of glomerular diseases$25,000
Funding Body: University of Newcastle

Project Team
Doctor Severine Roselli, Doctor Jude Weidenhofer, Emeritus Professor Leonie Ashman
SchemeRole
Near Miss GrantInvestigator
Total AmountFunding StartFunding Finish
$25,00020112011
GNo:G1001053

2010 (4 grants)

HMRI MRSP Infrastructure Grant (10-11) - CANCER$504,071
Funding Body: Hunter Medical Research Institute

Project Team
Emeritus Professor Leonie Ashman, Conjoint Professor Stephen Ackland
SchemeRole
NSW MRSP Infrastructure GrantChief Investigator
Total AmountFunding StartFunding Finish
$504,07120102010
GNo:G1100269

Laser microdissection microscopy system for cell and development biology$350,000
Funding Body: ARC (Australian Research Council)

Laser microdissection microscopy system for cell and development biology$215,000
Funding Body: University of Newcastle

ABI 7500 Real Time PCR System $34,000
Funding Body: NHMRC (National Health & Medical Research Council)

2009 (9 grants)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000
Funding Body: ARC (Australian Research Council)

Tetraspanin proteins in prostate cancer progression and prognosis$341,000
Funding Body: Cancer Council NSW

Project Team
Emeritus Professor Leonie Ashman, Doctor Nikki Verrills, Conjoint Professor Jim Denham
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$341,00020092011
GNo:G0188877

MRSP Infrastructure (09-10) Cancer$283,916
Funding Body: Hunter Medical Research Institute

Project Team
Emeritus Professor Leonie Ashman, Conjoint Professor Stephen Ackland
SchemeRole
NSW MRSP Infrastructure GrantChief Investigator
Total AmountFunding StartFunding Finish
$283,91620092010
GNo:G0900172

Confocal Laser Scanning Microscopy for Live Cell Imaging$275,000
Funding Body: ARC (Australian Research Council)

IVIS Lumina II fluorescence and bioluminescence imager for in vivo analysis of tumour growth and metastasis in mouse models$153,200
Funding Body: Cancer Institute NSW

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$153,20020092009
GNo:G0189634

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000
Funding Body: ARC (Australian Research Council)

Study of c-KIT mutations in familial gastrointestinal stromal tumours and malignant melanoma$44,720
Funding Body: Pfizer Australia

Project Team
Mr Ricardo Vilain, Professor Rodney Scott, Emeritus Professor Leonie Ashman
SchemeRole
Cancer Research GrantInvestigator
Total AmountFunding StartFunding Finish
$44,72020092009
GNo:G0189919

Identification of genetic modifiers of kidney disease$25,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Severine Roselli, Emeritus Professor Leonie Ashman, Professor Rodney Scott
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$25,00020092009
GNo:G0189793

3rd European Conference on Tetraspanins, Paris, 10-11 September 2009$1,175
Funding Body: University of Newcastle

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,17520092009
GNo:G0900245

2008 (4 grants)

HMRI Cancer Research Program - MRSP Infrastructure$1,031,290
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Stephen Ackland, Emeritus Professor Leonie Ashman, Professor John Forbes, Conjoint Professor Jim Denham, Conjoint Professor Peter Hersey, Professor Gordon Burns, Professor Adam McCluskey, Doctor Nikki Verrills
SchemeRole
NSW MRSP Infrastructure GrantInvestigator
Total AmountFunding StartFunding Finish
$1,031,29020082009
GNo:G0188622

PP2A: a novel target for leukaemia therapy$300,000
Funding Body: Cancer Council NSW

Project Team
Doctor Nikki Verrills, Emeritus Professor Leonie Ashman, Professor Alistair Sim, Associate Professor Danilo Perrotti, Assoc. Prof Timothy Hughes, Dr David Thomas
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$300,00020082010
GNo:G0187694

Role of tetraspanin proteins in human breast and prostate cancer$75,000
Funding Body: Hunter Medical Research Institute

Project Team
Emeritus Professor Leonie Ashman, Doctor Severine Roselli
SchemeRole
Mary Minto Sawyer GrantChief Investigator
Total AmountFunding StartFunding Finish
$75,00020082010
GNo:G0188187

FASEB Summer Research conference $2,500
Funding Body: University of Newcastle

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,50020082008
GNo:G0189020

2007 (6 grants)

FACSAria - Fluorescence activated cell sorter$300,000
Funding Body: Cancer Institute NSW

Project Team
Doctor Nikki Verrills, Emeritus Professor Leonie Ashman, Laureate Professor John Aitken, Professor Eileen McLaughlin, Professor Alistair Sim, Doctor Rick Thorne, Doctor Jennette Sakoff
SchemeRole
Infrastructure GrantsInvestigator
Total AmountFunding StartFunding Finish
$300,00020072007
GNo:G0187666

HMRI Contribution toward FACSAria - Fluorescence activated cell sorter$52,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Nikki Verrills, Emeritus Professor Leonie Ashman, Laureate Professor John Aitken, Professor Eileen McLaughlin, Professor Alistair Sim, Doctor Rick Thorne, Doctor Jennette Sakoff
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$52,00020072007
GNo:G0188207

Activity of kinase inhibitors on mutant forms of c-KIT in GIST and AML$27,500
Funding Body: Novartis Pharmaceuticals Australia Pty Limited

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$27,50020072007
GNo:G0188467

Polymerase Chain Reaction (PCR) machine and Spectrophotometer$20,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Leonie Ashman, Professor Alistair Sim, Doctor Nikki Verrills
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$20,00020072007
GNo:G0188195

Regulation of cancer cell behaviour by tetraspanin molecular complexes$16,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Judith Scott, Emeritus Professor Leonie Ashman
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$16,00020072007
GNo:G0187242

Beatson International Cancer Conference Molecular Cancer Thereapies: new challenges and horizons, Caledonian University, Glasgow, UK, 17/6/2007 - 20/6/2007$2,500
Funding Body: University of Newcastle

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,50020072007
GNo:G0187736

2006 (4 grants)

2006 Research Fellowship$776,824
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Research FellowshipsChief Investigator
Total AmountFunding StartFunding Finish
$776,82420062011
GNo:G0185093

PRC - Priority Research Centre for Bioinformatics, Biomarker Discovery & Information-Based Medicine (CIBM)$621,143
Funding Body: University of Newcastle

Project Team
Professor Pablo Moscato, Professor Rodney Scott, Emeritus Professor John Rostas, Professor John Forbes, Conjoint Professor Peter Hersey, Conjoint Professor Stephen Ackland, Conjoint Professor Wayne Smith, Emeritus Professor Peter Dunkley, Emeritus Professor Leonie Ashman, Professor John Attia, Associate Professor Phillip Dickson, Associate Professor Liz Milward, Professor Alistair Sim, Associate Professor Paul Tooney, Associate Professor Regina Berretta, Conjoint Professor David Sibbritt, Conjoint Professor Chris Levi, Professor Xu Dong Zhang, Conjoint Associate Professor Patricia Crock, Conjoint Associate Professor Jeannette Lechner-Scott
SchemeRole
Priority Research CentreInvestigator
Total AmountFunding StartFunding Finish
$621,14320062013
GNo:G0186919

Structural studies of the binding of clinically relevant small-molecule injibitors to wildtype and mutant receptor tyrosine kinases$20,000
Funding Body: University of Newcastle

Project Team
Conjoint Associate Professor Renate Griffith, Emeritus Professor Leonie Ashman
SchemeRole
Pilot GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020062007
GNo:G0186710

BioRad Mini-PROTEAN3 Electrophoresis system$995
Funding Body: Hunter Medical Research Institute

Project Team
Emeritus Professor Leonie Ashman, Associate Professor Phillip Dickson, Emeritus Professor Peter Dunkley, Emeritus Professor John Rostas, Professor Judith Scott, Professor Alistair Sim, Doctor Nikki Verrills
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$99520062006
GNo:G0187280

2005 (9 grants)

Role of the tetraspanin CD151 in epithelial biology and cancer$447,750
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$447,75020052007
GNo:G0183903

CD151 and functional overlap in tetraspanins$219,303
Funding Body: ARC (Australian Research Council)

Project Team
Emeritus Professor Leonie Ashman, Dr Mark Wright
SchemeRole
Discovery ProjectsChief Investigator
Total AmountFunding StartFunding Finish
$219,30320052007
GNo:G0184421

Protein kinase inhibitors for the treatment of acute myeloid leukaemia$217,500
Funding Body: Anthony Rothe Memorial Trust

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$217,50020052007
GNo:G0184574

High throughput proteomics - Thermo Finnigan ProteomeX LCQ Integrated Proteomicis Workstation$207,189
Funding Body: ARC (Australian Research Council)

Mechanisms of drug resistance in acute myeloid leukaemia$156,200
Funding Body: Leukaemia Foundation of NSW

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$156,20020052006
GNo:G0184615

2005 RIBG allocation$89,711
Funding Body: University of Newcastle

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Research Infrastructure Block Grant (RIBG)Chief Investigator
Total AmountFunding StartFunding Finish
$89,71120052005
GNo:G0185800

How the cell surface protein, CD151 promotes invasive behaviour in breast cancer$15,000
Funding Body: Hunter Medical Research Institute

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Mary Minto Sawyer GrantChief Investigator
Total AmountFunding StartFunding Finish
$15,00020052005
GNo:G0185658

Oolemmal receptors - the role of the tetraspanin CD151 in sperm-egg fusion$7,537
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin, Emeritus Professor Leonie Ashman
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$7,53720052005
GNo:G0184625

International Tetraspanins mini-symposium, June 30-July 1 2005, Federation of American Societies for Experimental Biology Summer Research Conference 16-21 July 2005$2,400
Funding Body: University of Newcastle

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,40020052005
GNo:G0185496

2004 (5 grants)

Biacore3000-Expansion of Proteomics Facility$187,341
Funding Body: ARC (Australian Research Council)

Project Team
Professor Alistair Sim, Laureate Professor John Aitken, Emeritus Professor Peter Dunkley, Emeritus Professor John Rostas, Associate Professor Phillip Dickson, Emeritus Professor Leonie Ashman, Professor Roger Smith, Professor Gordon Burns, Professor Adam McCluskey, Associate Professor Paul Tooney, Dr Fraser Ross, Conjoint Professor Ray Rose
SchemeRole
Linkage Infrastructure Equipment & Facilities (LIEF)Investigator
Total AmountFunding StartFunding Finish
$187,34120042004
GNo:G0183030

New drugs targeting protein kinases$17,000
Funding Body: Hunter Medical Research Institute

Project Team
Emeritus Professor Leonie Ashman, Professor Adam McCluskey
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$17,00020042004
GNo:G0183751

Characterisation of a novel recepto-mediated signal transduction pathway in human spermatozoa.$14,000
Funding Body: University of Newcastle

Project Team
Associate Professor Brett Nixon, Emeritus Professor Leonie Ashman
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$14,00020042004
GNo:G0183444

Is CD151 a co-receptor for human papilloma virus$12,395
Funding Body: University of Newcastle

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$12,39520042004
GNo:G0183418

FASEB Summer Research Conference: Advances in Tetraspanin Research, 19-24 June 2004, USA$2,400
Funding Body: University of Newcastle

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,40020042004
GNo:G0184098

2003 (3 grants)

Detection of mutations in c-kit in paediatric mastocytosis patient samples and structural analysis of the interaction between the D816VKit mutant and inhibitor$17,000
Funding Body: Hunter Medical Research Institute

Project Team
Emeritus Professor Leonie Ashman, Dr Petranel Ferrao
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$17,00020032003
GNo:G0182632

Molecular basis of cellular localisation of a cell membrane protein, CD151.$15,500
Funding Body: University of Newcastle

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$15,50020032003
GNo:G0182464

Beatson Conference: Cell signalling and Cancer, Glasgow, Scotland 6-9 July, 2003$2,400
Funding Body: University of Newcastle

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,40020032003
GNo:G0183163

2002 (9 grants)

Proteomic and Genomic Analysis Facility.$473,332
Funding Body: Wellcome Trust

Project Team
Professor Alistair Sim, Emeritus Professor Peter Dunkley, Emeritus Professor John Rostas, Professor Rodney Scott, Emeritus Professor Leonie Ashman
SchemeRole
Major Equipment AwardInvestigator
Total AmountFunding StartFunding Finish
$473,33220022004
GNo:G0181527

c-Kit signalling and cellular responses in haemopoietic cells$470,250
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Research FellowshipsChief Investigator
Total AmountFunding StartFunding Finish
$470,25020022005
GNo:G0181693

c-Kit signalling and cellular responses in haemopoietic cells$377,024
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$377,02420022004
GNo:G0181692

Use of retroviral libraries to characterise mechanisms of drug resistance in leukaemia$240,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Dr Petranel Ferrao, Emeritus Professor Leonie Ashman, Dr A Zannettino, Dr T Hughes
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$240,00020022003
GNo:G0181690

Molecular determinants of subcellular localisation and function of the transmembrane 4 superfamily protein, PETA-3$107,512
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$107,51220022002
GNo:G0181691

Role of PETA-3/CD151 in epithelial cancer invasion and metastasis.$70,008
Funding Body: Cancer Council NSW

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$70,00820022002
GNo:G0181686

Peltier Thermal Cycler and associated equipment essential for establishing cDNA Retroviral Libraries$21,315
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Emeritus Professor Leonie Ashman, Dr Petranel Ferrao, Professor Gordon Burns, Professor Alistair Sim, Emeritus Professor Peter Dunkley, Emeritus Professor John Rostas, Associate Professor Phillip Dickson, Professor Dirk Van Helden, Dr Perry Hartfield
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$21,31520022002
GNo:G0181919

A tissue culture system for antibody production$14,265
Funding Body: University of Newcastle

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
New Staff GrantChief Investigator
Total AmountFunding StartFunding Finish
$14,26520022002
GNo:G0182574

FASEB Summer Research Conference: 2nd International Conf. on Tetraspanin Proteins Tuscan, AZ, USA, 15 - 20 June, 2002$2,500
Funding Body: University of Newcastle

Project Team
Emeritus Professor Leonie Ashman
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,50020022002
GNo:G0181991

2001 (5 grants)

c-KIT signalling and cellular responses in haemopoietic cells.$125,688
Funding Body: National Health & Medical Research Council

SchemeRole
ProjectChief Investigator
Total AmountFunding StartFunding Finish
$125,68820012001
GNo:17563889

Molecular determinants of subcellular localisation and function of the transmembrane 4 superfamily protein, PETA-3.$105,162
Funding Body: National Health & Medical Research Council

SchemeRole
ProjectChief Investigator
Total AmountFunding StartFunding Finish
$105,16220012001
GNo:17563958

c-KIT signalling and cellular responses in haemopoietic cells.$85,000
Funding Body: National Health & Medical Research Council

SchemeRole
Research FellowshipChief Investigator
Total AmountFunding StartFunding Finish
$85,00020012001
GNo:17563802

Role of PETA-3/CD151 in epithelial cancer invasion and metastasis.$60,308
Funding Body: Cancer Council SA

SchemeRole
ProjectChief Investigator
Total AmountFunding StartFunding Finish
$60,30820012001
GNo:17564642

Use of retroviral expression libraries to characterise mechanisms of drug resistance in leukaemia, $12,000
Funding Body: National Health & Medical Research Council

SchemeRole
ProjectInvestigator
Total AmountFunding StartFunding Finish
$12,00020012001
GNo:17564584
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Research Supervision

Number of current supervisions2
Total current UoN PhD EFTSL0.2

For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20112015PhD (Medical Biochemistry)Co-SupervisorThe Role of CD151 in Glomerular Diseases
20112015PhD (Medical Biochemistry)Co-SupervisorAn Investigation into Micro-RNA Regulation of Tetraspanins CD151 and CD9 in Breast and Prostate Cancer Progression

Past Supervision

YearProgramSupervisor TypeResearch Title
2014PhD (Medical Biochemistry)Co-SupervisorTargeting PP2A Activation as a Novel Therapeutic Strategy for Receptor Tyrosine Kinase Driven Leukemia
2013PhD (Medical Genetics)Co-SupervisorActivating Kinase Mutations in Melanoma
2013PhD (Medical Biochemistry)Principal SupervisorTetraspanins as Biomarkers and Causative Proteins in Prostate Cancer
2010PhD (Medical Biochemistry)Co-SupervisorRegulation of the Tumour Suppressor PP2A by Oncogenic Tyrosine Kinases
2010PhD (Medical Biochemistry)Principal SupervisorSmall Molecule Inhibitors for Type III Receptor Tyrosine Kinases
2009PhD (Medical Biochemistry)Principal Supervisorc-KIT Polymorphisms in Pediatric Mastocytosis and Comparative Analysis of Wild Type c-KIT and the Asp816Val Mutant
2007M Sc (Medical Biochemistry)[R]Principal SupervisorThe Role of the Tetraspanin CD151 in Integrin/Growth Factor Receptor Complexes and Its Influence on Cancer Cell Behaviour
2005PhD (Medical Biochemistry)Principal SupervisorResistance to imatinib (STI 571) conferred by point mutations of Kit and BCR/ABL
2004PHD Biochemistry & Cell Biology
University of Adelaide
Principal SupervisorMolecular and Cellular Studies of Isoforms of c-KIT
2004PhD (Medical Biochemistry)Sole SupervisorSubcellular Localisation and Internalisation of the Tetraspanin, CD151: Role of the Cytoplasmic Domains
2003PHD Behavioural Science N.E.C.
University of Adelaide
Sole SupervisorReceptor tyrosine kinase c-KIT:signal transduction and biological response
2002PHD Biochemistry & Cell Biology
University of Adelaide
Sole SupervisorFunction of the soluble c-KIT extracellular domain
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Emeritus Professor Leonie Ashman

Work Phone(08) 8376 9069
Cell / Mobile Phone0419840829
Email
PositionsConjoint Professor
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine
The University of Newcastle, Australia
Emeritus Professor
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine
The University of Newcastle, Australia
Focus AreaMedical Biochemistry
Office
-,
-,
Adelaide SA
URL:www.newcastle.edu.au/profile/leonie-ashman