Associate Professor Lisa Wood

Associate Professor Lisa Wood

Associate Professor

School of Biomedical Sciences and Pharmacy (Pharmacy and Experimental Pharmacology)

Better eating, better breathing

Turning familiar anecdotes into effective antidotes, Associate Professor Lisa Wood's nutritional biochemistry research is proving there are crucial links between what we eat and how we breathe.

Lisa Wood 

Associate Professor Lisa Wood has developed something of a research niche. The enterprising educator and investigator studies both nutrition and inflammation, creatively combining the two to provide evidenced based dietary advice on respiratory disease management.

"I didn't have a particular interest in respiratory when I started," she recalls.

"Exploring nutritional approaches to disease management was a direction I took when I saw an unmet need."

Evolving this specialist area for the past 15 years, however, Lisa has made a number of significant discoveries. Together with her team at the Hunter Medical Research Institute (HMRI), the leader of the Nutrition Research group in the Priority Research Centre for Asthma and Respiratory Diseases examines the mechanisms by which dietary factors, including antioxidants, fatty acids, obesity and soluble fibre, affect the biochemical and physiological outcomes of respiratory disease. Principally demonstrating that short-term nutritional manipulation can modify blood lipid profiles, airway inflammation, asthma control, lung function and responses to asthma medications, such as Ventolin, she's also put science behind some 'very strong' perceptions and hearsay.

"People seem to know food is important in the management of asthma and other respiratory diseases even though there is so little data available," she claims.

"It's a curious thing."

The ambitious academic is similarly aiming to highlight 'great' community interest in this scope of research.

"What we do is incredibly translatable and applied," Lisa concedes.

"This is because people are trying to manage their asthma by changing their diet and as such, they need to be provided with specific guidelines."

Diet detective

Lisa began her research career with a PhD in Nutrition and Dietetics in 2001. Collaborating with the University of Newcastle and Westmead Children's Hospital during the four-year project, she studied the relationship between antioxidants and oxidative stress in young cystic fibrosis patients.

"People with this disease have a very different eating pattern. They are recommended a high-fat/high-energy diet because they don't absorb food properly," the nutritional biochemist explains.

"Eating lots of calorie-rich foods means they'll get enough energy to grow."

Lisa's investigation explored the effect of high fat diets in these patients and also identified a link between lung health and antioxidant levels in the body.

"Increasing antioxidant levels was found to be associated with improved lung function in patients with cystic fibrosis," she divulges.

Continuing this work on antioxidants with the HMRI's Respiratory Research Group from 2002-2006, the National Health and Medical Research Council Australian Training Research Fellow looked to translate some of her PhD research to another airways disease – asthma.

"It has a very different pathology to cystic fibrosis," she asserts.

"But it was again about using nutritional approaches to combat inflammation."

Moving to whole food interventions this time around, Lisa delivered antioxidants to asthma patients in the form of fruit and vegetables. The 'high' fruit and vegetable diet group consumed two serves of fruit and five serves of vegetables per day to meet current dietary guidelines, while the 'low' fruit and vegetable diet group consumed one serve of fruit and two serves of vegetables per day, which is the usual intake for Australian adults.

"We compared what people should be eating with what they are actually eating," she says.

"In a three-month period we found that those in the 'low' group had more than twice the risk of having an asthma attack than those in the 'high' group."

"So consuming lots of fruits and vegetables, which are high in antioxidants and soluble fibre, is important in controlling and reducing intermittent asthma flare-ups."

Hoping this research is as translatable as it is applied, Lisa is now in the process of undertaking a similar study with children.

"Asthma is more prevalent in young people so we're really hoping we can use the dietary approach to reduce their risk of picking up a viral infection or having it move on to an exacerbation," she reveals.

"The other great thing about a high fruit and vegetable diet is that it has multiple health benefits."

"It's an appealing strategy."

Foods that harm and foods that heal

Lisa extended her studies to investigate the roles of fatty acids and obesity in respiratory disease after procuring the prestigious University of Newcastle Brawn Fellowship in 2007. Seeking to examine the effects of different types of dietary fats on different types of bronchodilators, the interdisciplinary researcher demonstrated for the first time that nutritional factors could modulate airway inflammation and pharmacological responses.

"Bronchodilators are drugs that widen the bronchi. An example is Ventolin which is taken by inhalation to alleviate asthma symptoms," she clarifies.

"The key observation underpinning this project is that when people eat lots of fatty foods, it reduces the efficacy of their Ventolin."

"Bronchodilators are the first thing people go to when they're experiencing an asthma flare-up, so it's important we understand why they don't work as well when high-fat foods are consumed."

"It has major implications for the health and safety of asthmatics who are experiencing a potentially life-threatening asthma episode."

Currently working with bariatric surgeons at Lake Macquarie and Lingard Private Hospitals to explore the role of adipose tissue macrophages in obese asthma, Lisa is adding yet another dimension to her research. Fat samples collected during bariatric surgery are brought back to the labs at HMRI, to understand how this tissue could be driving airway inflammation.

"When someone is obese, they develop fat around their organs," the Associate Editor of Respirology explains.

"But it doesn't just sit there doing nothing – the fat actively releases chemicals into the bloodstream."

"Those chemicals then reach different organs and damage them, and this is why obesity is related to so many other diseases."

Hypothesising the same thing happens in asthma, Lisa is after scientific proof that chemicals in the bloodstream also reach the lungs and stop them working efficiently.

"Once you know what the tissue is actually doing you can get creative in how you prevent its effects," she reveals.

"Having this understanding opens up the way to develop new therapies."

Simultaneously running a clinical trial to examine the effects of soluble fibre on the gut microbiome and immune responses in asthma, Lisa is addressing airway inflammation from multiple angles.

"No one has ever done an intervention to see if fibre supplements affect the airways in humans," she says.

"It's only been done in animals, with exciting results."

"Now we are extending the investigation to humans."

Engaging the next generation

Combining this research expertise with more than a decade's worth of teaching experience, Lisa also teaches undergraduate students and supervises a team of PhD students at the University of Newcastle. Chiefly focusing on the biochemical and nutritional aspects of human health, both roles have a strong synergy with her multidisciplinary research endeavours.

"I'm very lucky that I get to teach what I am researching," she admits.

"It gives me an opportunity to talk to students with similar interests and feed them into the research groups at the HMRI and University's Priority Research Centre for Asthma and Respiratory Diseases."

"Most of the members of my team actually come through the undergraduate programs."

A 'very proud' leader both in and out of the laboratory, Lisa has nothing short of praise when it comes to commenting further on her colleagues' collective work ethic.

"Data from five of our recent publications was included in last year's National Asthma Council 'Australian Asthma Handbook', which was very rewarding," she says.

"We're finally starting to provide definitive advice after all these years of research."

A complete picture

Lisa's research hope for the not-so-distant future is two-pronged – provide a comprehensive plan on how people should approach their diet when they have a disease involving airway inflammation, and secure more funding opportunities for work that is of increasing interest to the general public.

"They're the ultimate goals," she declares.

"Any research that crosses disciplines can be difficult to fund because it doesn't fit into any one category – but to me, that's the research that is most worthwhile."

Better eating, better breathing

Turning familiar anecdotes into effective antidotes, Associate Professor Lisa Wood's nutritional biochemistry research is proving there are crucial links betw

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Career Summary

Biography

Associate Professor Wood leads the Nutrition programme within the Centre for Asthma and Respiratory Diseases, University of Newcastle. Dr Wood is a nutritional biochemist, who has been working in the area of nutrition and inflammation for over 15 years. Dr Wood completed her PhD in 2001, in Nutrition & Dietetics, at the University of Newcastle. Her PhD studied the relationship between antioxidants and oxidative stress in respiratory disease, in particular cystic fibrosis (CF). From 2002-2006, she undertook a postdoctoral fellowship (NHMRC Australian Training Research Fellowship), in the Respiratory Research Group, Hunter Medical Research Institute, Newcastle. Throughout this fellowship, she continued her research on dietary factors influencing respiratory diseases, in particular asthma. In 2007, she was awarded a Brawn postdoctoral fellowship at the University of Newcastle and during this time, she has extended her work to investigate the roles of dietary fat and obesity as promoters of airway inflammation. In 2010, Dr Wood took up an academic position in the School of Biomedical Sciences, University of Newcastle, in which she combines both research and teaching responsibilities.

Dr Wood has established and leads a research team, including 10 PhD students, 1 Honours student and 2 postdoctoral researchers. Dr Wood's team is investigating mechanisms by which dietary factors, including antioxidants, fatty acids, soluble fibre and obesity, affect blood lipid profiles, systemic and airway inflammation, as well as physiological outcomes such as lung function and arterial compliance. She has a strong publication record, including >85 publications, with publications in the highest impact specialty journals, eg J Allergy and Clin Immunol (IF 11), Am J Resp Crit Care Med (IF 11) and Am J Clin Nutr (IF 6). She has also produced >160 conference abstracts, 6 book chapters, 2 patents and 1 government report. In 2013, she co-edited a book on Nutrition and Physical Activity in Inflammatory Diseases. Demonstration of A/Prof Wood's contribution in this area is the recently published Asthma Management Handbook and National Asthma Council brochure series for health professionals and consumers, which included data from several of her recent publications. The excellence of Dr Wood’s research has been recognized by various prizes and awards, including 2012 University of Newcastle Vice Chancellor’s Faculty award for Research Excellence, 2011 Hunter Children’s Research Foundation Research Mentor of the Year, 2011 Nutrition Society of Australia Research Award, 2011 Nutrition Society of Australia Mid-career Travel fellowship for excellence in nutrition research, 2010 Thoracic Society of Australia and New Zealand and National Asthma Council Prize, 2009 HMRI Early Career Researcher award, 2008 NSW Young Tall Poppy award, 2008 University of Newcastle Faculty of Health Research Award, 2007 NSW Office for Science & Medical Research Postdoctoral award for Excellence in Medical Research. Dr Wood has served in various positions for the Nutrition Society of Australia (NSA), including Honorary Secretary, National Conference Programme Committee, Editorial Board and National Council. Dr Wood is a member of the Thoracic Society of Australia & New Zealand and has served as Convenor for the Asthma and Allergy Special interest group.

Research Expertise
Dr Wood is a Registered Nutritionist and Nutritional Biochemist, whose research focuses on the investigation of nutritional approaches to managing respiratory disease, such as asthma and chronic obstructive pulmonary disease (COPD). There is a strong community interest in dietary approaches to managing these diseases. However, due to a lack of good quality scientific data, there is currently no specific dietary advice available. Dr Wood’s research addresses this need, and has already made significant progress, by demonstrating that short-term dietary manipulation modifies respiratory outcomes. Dr Wood’s aim is to provide the scientific basis for developing definitive dietary advice and informing disease management guidelines for respiratory disease.

Research Themes

1. Antioxidants: Dr Wood has been leading a programme of work examining the role of antioxidants in the management of asthma, which has been supported by an NHMRC project grant. This work has shown that a high fruit and vegatable diet reduces the risk of asthma exacerbation.

2. Fatty acids: Dr Wood has demonstrated, for the first time, that dietary factors can modulate airway inflammation and bronchodilator responses. This observation forms the basis of a current NHMRC project grant, examining the effect of different types of fatty acids on different types of bronchodilators.          

3. Obesity and Inflammation: Dr Wood’s team is undertaking a series of projects looking at the contribution of obesity to airways disease, via the mechanisms of both systemic and airway inflammation. A particular focus is the role of adipose tissue macrophages in obese asthma.                   

4. Fibre and inflammation: Dr Wood is currently undertaking a clinical trial, examining the effects of soluble fibre on the gut microbiome and immune responses in asthma.

Teaching Expertise
Undergraduate Teaching: Dr Wood’s undergraduate teaching focuses on biochemical and nutritional aspects of human health and disease, which she teaches at 2nd (HUBS2207: Human Metabolism and Nutritional Biochemistry) and 3rd (HUBS3280: Advanced Nutritional Biochemistry) year levels. She also teaches clinical research skills (HUBS3410: Advanced design in research methods and HUBS3204: Professional Skills in Biomedical Science). Thus her undergraduate teaching has strong synergy with her research programme, which focuses on clinical nutrition. Dr Wood’s teaching covers a broad range of fields including biochemistry, physiology, anatomy, microbiology and immunology, to describe the complex aspects of digestion, absorption, transport, metabolism and excretion of nutrients present in foods in human health and diseased states. Her background in these disciplines and experience as a clinical researcher, allows her to give relevance to the scientific aspects of nutrition and metabolism, by considering them in a clinical context. Dr Wood holds a Graduate Certificate in Tertiary Teaching, from the University of Newcastle (2013).

Postgraduate teaching: RHD student completions: 8 PhDs, 2 Masters and 5 Honours - Current supervision: 10 PhD students (3 as primary, 7 as co-supervisor).

External Teaching Forums: - Dr Wood is regularly invited to provide educational sessions to the community and professional groups including: Hunter Medical Research Institute (HMRI), Asthma Foundation of NSW, Asthma and Respiratory Educators Association

Administration
2010–ongoing: Research Committee, School of Biomedical Sciences and Pharmacy

2006-ongoing: Research Higher Degree Committee - 2010:

2012-2014: Honorary Secretary, Nutrition Society of Australia (NSA)

2008-2014: NSA National Council member

2008-2014: NSA National Programme Committee member

2008- 2012: Chair, NSA (Newcastle branch)

2007-2009: Chair, Organising Committee for the 2009 NSA National Conference

Editorial responsibilities: Dr Wood is Associate Editor for Respirology and Editorial Board member for Nutrients.

Peer review of Manuscripts: Dr Wood is a regular reviewer (2/month) for international journals in nutrition and respiratory medicine, including European Respiratory Journal, Clinical and Experimental Allergy, Thorax, Respirology, Free Radical Research, European Journal of Paediatrics and Respiratory Medicine, Journal of Nutritional Biochemistry, Age, Nutrition.

Peer Review of Grants: NHMRC, Australia Cystic Fibrosis Research Trust, HMRI, Calvery Mater Newcastle, Health Research Council of New Zealand, Health Research Board of Ireland, Prince Charles Hospital Foundation, Asthma UK Foundation.

Media: Dr Wood regularly contributes TV, radio, print media relating to her work. Her work has been featured in various forums including: ABC Catalyst, The Australian, The Age and SMH.


Qualifications

  • PhD, University of Newcastle
  • Bachelor of Science (Honours), University of Sydney
  • Bachelor of Science, University of Newcastle

Keywords

  • Antioxidants
  • Asthma
  • Fatty acids
  • Fibre
  • Human Metabolism
  • Inflammation
  • Nutrition
  • Nutritional Biochemistry
  • Obesity
  • Oxidative stress
  • Research Higher Degree Coordinator
  • Respiratory Disease

Fields of Research

Code Description Percentage
110299 Cardiorespiratory Medicine and Haematology not elsewhere classified 40
160599 Policy and Administration not elsewhere classified 30
111199 Nutrition and Dietetics not elsewhere classified 30

Professional Experience

UON Appointment

Title Organisation / Department
Associate Professor University of Newcastle
School of Biomedical Sciences and Pharmacy
Australia

Academic appointment

Dates Title Organisation / Department
1/07/2013 -  Associate Professor University of Newcastle
School of Biomedical Sciences and Pharmacy
Australia
1/01/2011 -  Trustee Australian Nutrition Trust
Australia
1/01/2011 - 1/06/2013 Senior Lecturer University of Newcastle
School of Biomedical Sciences and Pharmacy
Australia
1/02/2010 - 1/12/2010 Lecturer University of Newcastle
School of Biomedical Sciences and Pharmacy
Australia
1/01/2010 -  Research Higher Degree Coordinator University of Newcastle
School of Biomedical Sciences and Pharmacy
Australia
1/01/2008 -  Chair - Nutrition Society of Australia (Newcastle Group) Nutrition Society of Australia
Newcastle Group
Australia
1/01/2008 -  Membership - Nutrition Society of Australia, National Council Nutrition Society of Australia
National Council and Executive
Australia
1/01/2008 -  Membership - Australian Bone and Mineral Society Australian Bone and Mineral Society
Australia
1/01/2007 - 1/01/2010 Brawn Postdoctoral Fellowship University of Newcastle
School of Medicine and Public Health
Australia
1/09/2006 - 1/12/2009 Research Higher Degree Coordinator University of Newcastle
School of Medicine and Public Health
Australia
1/05/2006 - 1/01/2007 Asthma CRC Manager (programme 2.2) University of Newcastle
School of Medicine and Public Health
Australia
1/01/2006 -  Membership - Australian Society for Medical Research Australian Society for Medical Research (ASMR)
Australia
1/01/2004 -  Membership - Thoracic Society of Australia Thoracic Society of Australia
Australia
1/04/2002 - 1/04/2006 NHMRC Postdoctoral Fellow University of Newcastle
School of Medicine and Public Health
Australia
1/02/1998 - 1/07/2001 NHMRC Dora Lush Biomedical PhD Scholar

Nutrition & Dietetics

University of Newcastle
Medicine and Health Sciences
Australia

Professional appointment

Dates Title Organisation / Department
1/01/1992 - 1/12/1997 Graduate Management Trainee MasterFoods of Australia
Graduate Management Programme
Australia

Awards

Distinction

Year Award
2008 NSW & ACT Tall Poppy award
NSW Office for Science & Medical Research

Recipient

Year Award
1991 University medal
University of Sydney

Research Award

Year Award
2012 Vice Chancellor’s Faculty award for Research Excellence
University of Newcastle
2011 Research Mentor of the Year
Hunter Children`s Research Foundation
2011 Research award
Nutrition Society of Australia
2011 Mid career travel fellowship for excellence in nutrition science research
Nutrition Society of Australia
2010 National Asthma Council Prize
Thoracic Society of Australia and New Zealand
2009 Early Career Researcher of the Year
Hunter Medical Research Institute
2007 Postdoctoral award for Excellence in Medical Research
NSW Office for Science & Medical Research
2007 Travel award
The Thoracic Society of Australia and New Zealand
2007 Pulse Education Prize
Hunter Medical Research Institute
2006 Best poster prize
Asian Pacific Society of Respirology
2006 Travel award
The Thoracic Society of Australia and New Zealand
2006 Young Investigator award
Japanese Respiratory Society
2005 Travel award
The Thoracic Society of Australia and New Zealand
Edit

Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Book (1 outputs)

Year Citation Altmetrics Link
2013 Garg ML, Wood LG, Nutrition and Physical Activity in Inflammatory Diseases, CABI, Oxfordshire, 416 (2013) [A3]
Co-authors Manohar Garg

Chapter (6 outputs)

Year Citation Altmetrics Link
2015 Gleeson M, Elkington LJ, Pyne DB, Callister R, Wood LG, 'Inflammation and Immune Function: Can Antioxidants Help the Endurance Athlete?', Antioxidants in Sports Nutrition, CRC Press, Boca Raton, FL 171-181 (2015)
Co-authors Maree Gleeson, Robin Callister
2013 Garg ML, Wood LG, 'Role of omega-3 fatty acids in weight loss and maintenance', The Omega-3 Fatty Acid Deficiency Syndrome: Opportunities for Disease Prevention, Nova Science, Hauppaugue, NY 233-246 (2013) [B1]
Co-authors Manohar Garg
2013 Scott H, Wood LG, Garg ML, Gibson PG, 'Asthma and Inflammation', Nutrition and Physical activity in inflammatory diseases, CABI, Oxford, UK 299-321 (2013) [B1]
Co-authors Hayley Scott, Manohar Garg, Peter Gibson
2011 Wood LG, Garg ML, 'Macadamia nuts (Macadamia integrifolia and tetraphylla) and their use in hypercholesterolemic subjects', Nuts and Seeds in Health and Disease Prevention, Academic Press, San Diego 717-725 (2011) [B2]
DOI 10.1016/b978-0-12-375688-6.10085-4
Co-authors Manohar Garg
2007 Wood LG, Gibson PG, Garg ML, 'Alpha-tocopherol and cystic fibrosis', The Encyclopedia of Vitamin E, Centre for Agricultural Bioscience International, Wallingford, United Kingdom 708-718 (2007) [B1]
Co-authors Peter Gibson, Manohar Garg
1999 Wood LG, Collins CE, Garg ML, 'Oxidative stress and antioxidants in cystic fibrosis', Antiooxidants in Human Health and Disease, CAB International, Oxford UK 313-333 (1999) [B1]
Co-authors Clare Collins, Manohar Garg
Show 3 more chapters

Journal article (91 outputs)

Year Citation Altmetrics Link
2015 Dias CB, Phang M, Wood LG, Garg ML, 'Postprandial Lipid Responses do not Differ Following Consumption of Butter or Vegetable Oil when Consumed with Omega-3 Polyunsaturated Fatty Acids', Lipids, (2015)

Dietary saturated fat (SFA) intake has been associated with elevated blood lipid levels and increased risk for the development of chronic diseases. However, some animal studies ha... [more]

Dietary saturated fat (SFA) intake has been associated with elevated blood lipid levels and increased risk for the development of chronic diseases. However, some animal studies have demonstrated that dietary SFA may not raise blood lipid levels when the diet is sufficient in omega-3 polyunsaturated fatty acids (n-3PUFA). Therefore, in a randomised cross-over design, we investigated the postprandial effects of feeding meals rich in either SFA (butter) or vegetable oil rich in omega-6 polyunsaturated fatty acids (n-6PUFA), in conjunction with n-3PUFA, on blood lipid profiles [total cholesterol, low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and triacylglycerol (TAG)] and n-3PUFA incorporation into plasma lipids over a 6-h period. The incremental area under the curve for plasma cholesterol, LDL-C, HDL-C, TAG and n-3PUFA levels over 6 h was similar in the n-6PUFA compared to SFA group. The postprandial lipemic response to saturated fat is comparable to that of n-6PUFA when consumed with n-3PUFA; however, sex-differences in response to dietary fat type are worthy of further attention.

DOI 10.1007/s11745-015-4003-2
Co-authors Manohar Garg
2015 Berthon BS, Wood LG, 'Nutrition and Respiratory Health-Feature Review', NUTRIENTS, 7 1618-1643 (2015)
DOI 10.3390/nu7031618
2015 Scott HA, Latham JR, Callister R, Pretto JJ, Baines K, Saltos N, et al., 'Acute exercise is associated with reduced exhaled nitric oxide in physically inactive adults with asthma', Annals of Allergy, Asthma and Immunology, 114 470-479 (2015)

Background Although exercise has multiple health benefits, relatively little attention has been paid to its potential therapeutic effects in those with asthma. Objective To examin... [more]

Background Although exercise has multiple health benefits, relatively little attention has been paid to its potential therapeutic effects in those with asthma. Objective To examine the effects of acute exercise on inflammation in physically inactive and active adults with asthma. Methods Fourteen adults with asthma (n = 6 physically inactive, n = 8 physically active) completed (1) 30 minutes of moderate-intensity exercise on a treadmill and (2) 30 minutes of rest in random order, with 4 weeks between sessions. Exhaled nitric oxide (eNO) was measured before and after the intervention (0, 0.5, 1, 2, 4, and 24 hours). Blood inflammatory mediators were measured before and after the intervention (0, 2, and 24 hours). Results Physically inactive participants had a significant decrease in eNO 4 hours after exercise (-4.8 ppb, -6.4 to -0.5 ppb, P =.028), which was not observed in physically active participants (P =.362). Interluekin-1 receptor antagonist increased in the physically inactive group 2 hours after exercise, with this increase strongly correlated with the decrease in eNO at 4 hours (R = -0.685, P =.007) and 24 hours (R = -0.659, P =.014) after exercise. Interleukin-6 was increased significantly 2 hours after exercise in physically inactive participants. Blood neutrophils and nuclear factor erythroid 2-like 2 gene expression were increased 2 hours after exercise in the overall cohort. Conclusion This study demonstrates that acute moderate-intensity exercise is associated with decreased eNO in physically inactive adults with asthma and suggests that interluekin-1 receptor antagonist could have a role in mediating this effect. The attenuated response in physically active participants might be due to the sustained anti-inflammatory effects of exercise training. Future studies should investigate the impact of exercise intensity and exercise training on airway inflammation in those with asthma.

DOI 10.1016/j.anai.2015.04.002
Co-authors Katherine Baines, Hayley Scott, Robin Callister
2015 Wood LG, Shivappa N, Berthon BS, Gibson PG, Hebert JR, 'Dietary inflammatory index is related to asthma risk, lung function and systemic inflammation in asthma', Clinical and Experimental Allergy, 45 177-183 (2015)

Background: Asthma prevalence has increased in recent years, and evidence suggests that diet may be a contributing factor. Increased use of processed foods has led to a decrease i... [more]

Background: Asthma prevalence has increased in recent years, and evidence suggests that diet may be a contributing factor. Increased use of processed foods has led to a decrease in diet quality, which may be creating a pro-inflammatory environment, thereby leading to the development and/or progression of various chronic inflammatory diseases and conditions. Recently, the dietary inflammatory index (DII) has been developed and validated to assess the inflammatory potential of individual diets. Objective: This study aimed to examine the DII in subjects with asthma compared to healthy controls and to relate the DII to asthma risk, lung function and systemic inflammation. Methods: Subjects with asthma (n = 99) and healthy controls (n = 61) were recruited. Blood was collected and spirometry was performed. The DII was calculated from food frequency questionnaires administered to study subjects. Results: The mean DII score for the asthmatics was higher than the mean DII score for healthy controls (- 1.40 vs. - 1.86, P = 0.04), indicating that their diets were more pro-inflammatory. For every 1 unit increase in DII score, the odds of having asthma increased by 70% (OR: 1.70, 95% CI: 1.03, 2.14; P = 0.040). FEV1 was significantly associated with DII score (ß = - 3.44, 95% CI: - 6.50, - 0.39; P = 0.020), indicating that for every 1 unit increase in DII score, FEV1 decreased by 3.44 times. Furthermore, plasma IL-6 concentrations were positively associated with DII score (ß = 0.13, 95% CI: 0.05, 0.21; P = 0.002). Conclusion and Clinical Relevance: As assessed using the DII score, the usual diet consumed by asthmatics in this study was pro-inflammatory relative to the diet consumed by the healthy controls. The DII score was associated with increased systemic inflammation and lower lung function. Hence, consumption of pro-inflammatory foods may contribute to worse asthma status, and targeting an improvement in DII in asthmatics, as an indicator of suitable dietary intake, might be a useful strategy for improving clinical outcomes in the disease.

DOI 10.1111/cea.12323
Citations Scopus - 7Web of Science - 9
Co-authors Peter Gibson
2015 Wood LG, 'Omega-3 polyunsaturated fatty acids and chronic obstructive pulmonary disease', Current Opinion in Clinical Nutrition and Metabolic Care, (2015)
DOI 10.1097/MCO.0000000000000142
2015 Wood LG, 'Omega-3 polyunsaturated fatty acids and chronic obstructive pulmonary disease', Current Opinion in Clinical Nutrition and Metabolic Care, 18 128-132 (2015)

PURPOSE OF REVIEW: The aim of the present review was to summarize recent research developments relating omega-3 polyunsaturated fatty acids (PUFAs) and chronic obstructive pulmona... [more]

PURPOSE OF REVIEW: The aim of the present review was to summarize recent research developments relating omega-3 polyunsaturated fatty acids (PUFAs) and chronic obstructive pulmonary disease (COPD). RECENT FINDINGS: COPD is a chronic inflammatory disease; hence, omega-3 PUFAs may have beneficial effects. At present, however, there are limited data available regarding the potential for omega-3 PUFAs to be used therapeutically in COPD. In 2012-2013, several observational studies have emerged, which demonstrate that circulating omega-3 PUFA levels in COPD are inversely associated with systemic inflammation and positively associated with clinical outcomes. To date, all interventions incorporating omega-3 PUFAs in COPD have used nutrient combinations, such that the specific effects of omega-3 PUFAs cannot be determined. Three clinical trials in COPD are underway, which use therapeutic doses of omega-3 PUFAs alone, with positive results beginning to emerge in 2014. SUMMARY: Observational data support the hypothesis that omega-3 PUFAs may provide a therapeutic strategy for managing COPD. Several intervention trials using omega-3 PUFAs in COPD are underway, which will provide a substantive amount of new data to inform the field and allow evidence-based advice to be generated for patients with COPD in the near future.

DOI 10.1097/MCO.0000000000000142
2015 Williams RL, Wood LG, Collins CE, Callister R, 'Effectiveness of weight loss interventions - is there a difference between men and women: A systematic review', Obesity Reviews, 16 171-186 (2015)

Effective strategies are required to reduce the prevalence of overweight and obesity; however, the effectiveness of current weight loss programmes is variable. One contributing fa... [more]

Effective strategies are required to reduce the prevalence of overweight and obesity; however, the effectiveness of current weight loss programmes is variable. One contributing factor may be the difference in weight loss success between men and women. A systematic review was conducted to determine whether the effectiveness of weight loss interventions differs between men and women. Randomized controlled trials published up until March 2014 were included. Effect sizes (Hedges' g) were used to examine the difference in weight outcomes between men and women. A total of 58 studies met the eligibility criteria with 49 studies of higher quality included in the final data synthesis. Eleven studies that directly compared weight loss in men and women reported a significant sex difference. Ten of these reported that men lost more weight than women; however, women also lost a significant amount of weight. Analysis of effect sizes found small differences in weight loss favouring men for both diet (g=0.489) and diet plus exercise (g=0.240) interventions. There is little evidence from this review to indicate that men and women should adopt different weight loss strategies. Current evidence supports moderate energy restriction in combination with exercise for weight loss in both men and women.

DOI 10.1111/obr.12241
Citations Scopus - 2Web of Science - 1
Co-authors Robin Callister, Clare Collins
2015 Periyalil HA, Wood LG, Scott HA, Jensen ME, Gibson PG, 'Macrophage activation, age and sex effects of immunometabolism in obese asthma', EUROPEAN RESPIRATORY JOURNAL, 45 388-395 (2015)
DOI 10.1183/09031936.00080514
Citations Scopus - 1Web of Science - 1
Co-authors Peter Gibson, Hayley Scott
2015 Wood LG, 'Metabolic dysregulation. Driving the obese asthma phenotype in adolescents?', Am J Respir Crit Care Med, 191 121-122 (2015)
DOI 10.1164/rccm.201412-2221ED
2015 Berthon BS, Gibson PG, McElduff P, MacDonald-Wicks LK, Wood LG, 'Effects of short-term oral corticosteroid intake on dietary intake, body weight and body composition in adults with asthma - a randomized controlled trial.', Clin Exp Allergy, 45 908-919 (2015)
DOI 10.1111/cea.12505
Citations Scopus - 1Web of Science - 1
Co-authors Patrick Mcelduff, Lesley Wicks, Peter Gibson
2015 Grieger JA, Grzeskowiak LE, Wood LG, Clifton VL, 'Asthma control in pregnancy is associated with pre-conception dietary patterns', Public Health Nutrition, (2015)

Objective: To examine pre-conception dietary patterns in pregnant asthmatic women and to identify associations between maternal diet and asthma control during pregnancy. Design: C... [more]

Objective: To examine pre-conception dietary patterns in pregnant asthmatic women and to identify associations between maternal diet and asthma control during pregnancy. Design: Cross-sectional study. Pre-conception food frequency data were collected retrospectively. Asthma control was assessed using the Global Initiative for Asthma guidelines. Dietary patterns were derived using factor analysis. Binary logistic regression analyses were used to test the association between uncontrolled asthma and each dietary pattern (Z-score), with values presented as odds ratio and 95 % confidence interval. Setting: Antenatal clinic in a tertiary hospital, Adelaide, Australia, May 2009¿July 2013. Subjects: One hundred and fifty-eight asthmatic pregnant women. Results: Three dietary patterns were identified: (i) ¿high protein/fruit¿ (strong food group loadings for fish, meat, chicken, fruit); (ii) ¿high fat/sugar/takeaway¿ (takeaway foods, crisps, refined grains); and (iii) ¿vegetarian-type¿ (vegetables, fruit, soya milk, whole grains). A 1 sd increase in score on the high fat/sugar/takeaway pattern was associated with increased likelihood of uncontrolled asthma (adjusted OR=1·54; 95 % CI 1·07, 2·23; P=0·022). Women with uncontrolled asthma (n 115) had higher energy-adjusted intakes of saturated fat, monounsaturated fat, carbohydrate, sugar and fibre compared with women with controlled asthma (n 43, all P=0·05). Conclusions: Pre-pregnancy dietary patterns may influence maternal asthma control. Our work highlights the importance of achieving a healthy diet before pregnancy that is low in saturated fat, sugar and takeaway foods, and therefore higher in lean meats, poultry and fish, as well as fruits, vegetables and whole grains. A healthy dietary pattern should be encouraged in all asthmatic women who are of childbearing age, and should additionally be promoted before pregnancy and beyond.

DOI 10.1017/S1368980015001226
2015 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Determinants of weight loss success utilizing a meal replacement plan and/or exercise, in overweight and obese adults with asthma.', Respirology, 20 243-250 (2015)
DOI 10.1111/resp.12423
Citations Scopus - 1Web of Science - 1
Co-authors Philip Morgan, Manohar Garg, Hayley Scott, Peter Gibson, Robin Callister
2015 Scott HA, Latham JR, Callister R, Pretto JJ, Baines K, Saltos N, et al., 'Acute exercise is associated with reduced exhaled nitric oxide in physically inactive adults with asthma', Annals of Allergy, Asthma and Immunology, 114 470-479 (2015)

Background Although exercise has multiple health benefits, relatively little attention has been paid to its potential therapeutic effects in those with asthma. Objective To examin... [more]

Background Although exercise has multiple health benefits, relatively little attention has been paid to its potential therapeutic effects in those with asthma. Objective To examine the effects of acute exercise on inflammation in physically inactive and active adults with asthma. Methods Fourteen adults with asthma (n = 6 physically inactive, n = 8 physically active) completed (1) 30 minutes of moderate-intensity exercise on a treadmill and (2) 30 minutes of rest in random order, with 4 weeks between sessions. Exhaled nitric oxide (eNO) was measured before and after the intervention (0, 0.5, 1, 2, 4, and 24 hours). Blood inflammatory mediators were measured before and after the intervention (0, 2, and 24 hours). Results Physically inactive participants had a significant decrease in eNO 4 hours after exercise (-4.8 ppb, -6.4 to -0.5 ppb, P =.028), which was not observed in physically active participants (P =.362). Interluekin-1 receptor antagonist increased in the physically inactive group 2 hours after exercise, with this increase strongly correlated with the decrease in eNO at 4 hours (R = -0.685, P =.007) and 24 hours (R = -0.659, P =.014) after exercise. Interleukin-6 was increased significantly 2 hours after exercise in physically inactive participants. Blood neutrophils and nuclear factor erythroid 2-like 2 gene expression were increased 2 hours after exercise in the overall cohort. Conclusion This study demonstrates that acute moderate-intensity exercise is associated with decreased eNO in physically inactive adults with asthma and suggests that interluekin-1 receptor antagonist could have a role in mediating this effect. The attenuated response in physically active participants might be due to the sustained anti-inflammatory effects of exercise training. Future studies should investigate the impact of exercise intensity and exercise training on airway inflammation in those with asthma.

DOI 10.1016/j.anai.2015.04.002
Co-authors Robin Callister, Hayley Scott, Katherine Baines
2015 Scott HA, Latham JR, Callister R, Pretto JJ, Baines K, Saltos N, et al., 'Acute exercise is associated with reduced exhaled nitric oxide in physically inactive adults with asthma', Annals of Allergy, Asthma and Immunology, (2015)

Background: Although exercise has multiple health benefits, relatively little attention has been paid to its potential therapeutic effects in those with asthma. Objective: To exam... [more]

Background: Although exercise has multiple health benefits, relatively little attention has been paid to its potential therapeutic effects in those with asthma. Objective: To examine the effects of acute exercise on inflammation in physically inactive and active adults with asthma. Methods: Fourteen adults with asthma (n= 6 physically inactive, n= 8 physically active) completed (1) 30 minutes of moderate-intensity exercise on a treadmill and (2) 30 minutes of rest in random order, with 4 weeks between sessions. Exhaled nitric oxide (eNO) was measured before and after the intervention (0, 0.5, 1, 2, 4, and 24 hours). Blood inflammatory mediators were measured before and after the intervention (0, 2, and 24 hours). Results: Physically inactive participants had a significant decrease in eNO 4 hours after exercise (-4.8 ppb,-6.4 to-0.5 ppb, P= .028), which was not observed in physically active participants (P= .362). Interluekin-1 receptor antagonist increased in the physically inactive group 2 hours after exercise, with this increase strongly correlated with the decrease in eNO at 4 hours (R=-0.685, P= .007) and 24 hours (R=-0.659, P=.014) after exercise. Interleukin-6 was increased significantly 2 hours after exercise in physically inactive participants. Blood neutrophils and nuclear factor erythroid 2-like 2 gene expression were increased 2hours after exercise in the overall cohort. Conclusion: This study demonstrates that acute moderate-intensity exercise is associated with decreased eNO in physically inactive adults with asthma and suggests that interluekin-1 receptor antagonist could have a role in mediating this effect. The attenuated response in physically active participants might be due to the sustained anti-inflammatory effects of exercise training. Future studies should investigate the impact of exercise intensity and exercise training on airway inflammation in those with asthma. Trial registration: Australian New Zealand Clinical Trials Registry (http://www.anzctr.org.au), registration number ACTRN12613001014741.

DOI 10.1016/j.anai.2015.04.002
Co-authors Robin Callister, Katherine Baines, Hayley Scott
2015 Delaney JA, Thornton HR, Scott TJ, Ballard DA, Duthie GM, Wood LG, Dascombe BJ, 'Validity of Skinfold-Based Measures for Tracking Changes in Body Composition in Professional Rugby League Players.', Int J Sports Physiol Perform, (2015)
DOI 10.1123/ijspp.2015-0244
Co-authors Ben Dascombe
2015 Williams RL, Wood LG, Collins CE, Callister R, 'Comparison of fruit and vegetable intakes during weight loss in males and females.', Eur J Clin Nutr, (2015)
DOI 10.1038/ejcn.2015.123
Co-authors Robin Callister
2015 Thorburn AN, McKenzie CI, Shen S, Stanley D, Macia L, Mason LJ, et al., 'Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites.', Nat Commun, 6 7320 (2015)
DOI 10.1038/ncomms8320
Co-authors Peter Gibson, Vanessa Murphy, Joerg Mattes
2015 Haghi M, Traini D, Wood LG, Oliver B, Young PM, Chrzanowski W, 'A 'soft spot' for drug transport: Modulation of cell stiffness using fatty acids and its impact on drug transport in lung model', Journal of Materials Chemistry B, 3 2583-2589 (2015)

The impact of a polyunsaturated fatty acid, arachidonic acid (AA), on membrane fluidity of epithelial cells and subsequent modulation of the drug transport was investigated. Membr... [more]

The impact of a polyunsaturated fatty acid, arachidonic acid (AA), on membrane fluidity of epithelial cells and subsequent modulation of the drug transport was investigated. Membrane fluidity was assessed using molecular force microscopy. Calu-3 human bronchial epithelial cells were cultured on Transwell® inserts and the cell stiffness was assessed in the absence of fatty acids or in the presence of 30 µM AA. The morphology of the epithelial cells was distinctly different when AA was present, with the cell monolayer becoming more uniform. Furthermore the cell stiffness and variation in stiffness was lower in the presence of AA. In the fat-free medium, the median cell stiffness was 9.1 kPa which dropped to 2.1 kPa following exposure to AA. To further study this, transport of a common ß2-agonist, salbutamol sulphate (SS) was measured in the presence of AA and in a fat free medium. The transport of SS was significantly higher when AA was present (0.61 ± 0.09 µg versus 0.11 ± 0.003 µg with and without AA respectively). It was evidenced that AA play a vital role in cell membrane fluidity and drug transport. This finding highlights the significance of the dietary fatty acids in transport and consequentially effectiveness of medications used to treat pulmonary diseases such as asthma. This journal is

DOI 10.1039/c4tb01928h
2014 Wong R, Garg M, Wood L, Howe P, 'Antihypertensive Potential of Combined Extracts of Olive Leaf, Green Coffee Bean and Beetroot: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial', Nutrients, 6 4881-4894 (2014) [C1]
DOI 10.3390/nu6114881
Citations Scopus - 1
Co-authors Manohar Garg, Peter Howe, Rachel Wong
2014 Grieger JA, Wood LG, Clifton VL, 'Antioxidant-rich dietary intervention for improving asthma control in pregnancies complicated by asthma: Study protocol for a randomized controlled trial', Trials, 15 (2014) [C3]

Background: Asthma is the most prevalent chronic disease to complicate pregnancies worldwide, affecting around 12% of pregnant women in Australia. Oxidative stress and inflammatio... [more]

Background: Asthma is the most prevalent chronic disease to complicate pregnancies worldwide, affecting around 12% of pregnant women in Australia. Oxidative stress and inflammation manifest during pregnancy; however asthma in pregnancies further intensifies oxidative stress. Consumption of antioxidant-rich foods has been shown to be beneficial for asthma control in non-pregnant asthmatic adults. It has not been investigated whether antioxidant-rich foods can improve the elevated oxidative stress that occurs with asthma in pregnancy, thereby improving asthma control. The primary aim of this study is to determine whether increased consumption of antioxidant-rich foods for 12 weeks will improve maternal asthma control, compared to standard dietary intake during pregnancy.Methods/design: A 12 week, parallel randomized controlled trial will be conducted. One hundred and sixty eight pregnant women with mild, moderate, or severe asthma, currently using inhaled corticosteroids, and with poor diet quality, will be recruited at approximately12 weeks gestation. Following a 4 week run-in period, women will be randomized to either a 12 week antioxidant intervention (increased consumption of antioxidant-rich foods (=5 servings/day vegetables, =2 servings/day fruit, =8 1-Feb servings/day grains (mostly wholegrains), 3-4 serving/week lean meat) or standard pregnancy care. The primary outcome is asthma control score (decrease of 0.5, the minimally clinically significant change). Secondary outcomes include plasma antioxidants, markers of oxidative stress, and time to, and number of, exacerbations. With two-tailed t-tests at 80% power, a sample size of 52 completions per group is required. Allowing for a 78% retention including a 20% removal of women from the analysis due to non-compliance, we will recruit 168 women.Discussion: It is expected that this 12 week study will improve asthma control. This is significant because asthma is the most prevalent condition to complicate pregnancies and contributes to poor maternal, neonatal and infant health outcomes. Our research will provide the first evidence to show that, in pregnancy, consumption of antioxidant-rich foods is a key modifier of clinical asthma status. This research is crucial for contributing to the evidence base to inform future guidelines given existing clinical and research gaps.Trial registration: ACTRN12613000301763. © 2014 Grieger et al.; licensee BioMed Central Ltd.

DOI 10.1186/1745-6215-15-108
Citations Web of Science - 1
2014 Jensen ME, Gibson PG, Collins CE, Wood LG, 'Lean mass, not fat mass, is associated with lung function in male and female children with asthma', Pediatric Research, 75 93-98 (2014) [C1]

Background:Whether body composition is associated with lung function in asthmatic children has not been investigated. This study aimed to primarily investigate whether BMI z-score... [more]

Background:Whether body composition is associated with lung function in asthmatic children has not been investigated. This study aimed to primarily investigate whether BMI z-score and body composition were associated with respiratory function in asthmatic children.Methods:In a cross-sectional study, male (n = 27; mean age: 11.9 y (SD: 2.3)) and female (n = 21; mean age: 13.6 y (SD: 2.2)) asthmatic children underwent clinical assessment.Results:BMI z-score was associated with forced expiratory volume in 1 s (FEV 1; r = 0.458), forced vital capacity (FVC; r = 0.477), and total lung capacity (TLC; r = 0.451) in males only (P < 0.05). Total lean mass was associated with FEV 1 (r = 0.655), FVC (r = 0.562), and TLC (r = 0.635) in males, as was thoracic lean mass (FEV 1 (r = 0.573), FVC (r = 0.526), and TLC (r = 0.497); P < 0.05). TLC was associated with total (r = 0.522) and thoracic (r = 0.532) lean mass in females (P < 0.05). Fat mass was not associated with lung function in this group.Conclusion:Lean mass, not fat mass, is associated with lung function in children with asthma. The positive association between BMI z-score and respiratory function in male children is driven by lean mass. Although body weight can be easily monitored in the clinical setting, body composition can provide important information. Future research exploring lean mass and lung function associations could inform future interventions. Copyright © 2014 International Pediatric Research Foundation, Inc.

DOI 10.1038/pr.2013.181
Citations Scopus - 2Web of Science - 1
Co-authors Peter Gibson, Clare Collins
2014 Berthon BS, MacDonald-Wicks LK, Wood LG, 'A systematic review of the effect of oral glucocorticoids on energy intake, appetite, and body weight in humans', NUTRITION RESEARCH, 34 179-190 (2014) [C1]
DOI 10.1016/j.nutres.2013.12.006
Citations Scopus - 2Web of Science - 1
Co-authors Lesley Wicks
2014 Dias CB, Garg R, Wood LG, Garg ML, 'Saturated fat consumption may not be the main cause of increased blood lipid levels', Medical Hypotheses, 82 187-195 (2014)
DOI 10.1016/j.mehy.2013.11.036
Co-authors Manohar Garg
2014 Dias CB, Garg R, Wood LG, Garg ML, 'Saturated fat consumption may not be the main cause of increased blood lipid levels', Medical Hypotheses, 82 187-195 (2014) [C1]

Consumption of foods rich in saturated fatty acids (SFA) has often been associated with elevated blood lipid levels and consequently with risk for chronic diseases, including coro... [more]

Consumption of foods rich in saturated fatty acids (SFA) has often been associated with elevated blood lipid levels and consequently with risk for chronic diseases, including coronary heart disease. However, epidemiological and interventional studies on this topic are contradictory. While some studies have established a positive link, other studies have failed to show a significant association between saturated fat consumption and blood lipid levels, and others have even found an inverse association. Moreover, studies using animal models have demonstrated that dietary saturated fats raise blood lipid (cholesterol and triglycerides) levels only when the diet is deficient in omega-3 polyunsaturated fatty acids (n-3PUFA). The n-3PUFA are known for their potential in the management of hyperlipidaemia for the prevention of coronary heart disease, as well as for their anti-arrhythmic, anti-aggregatory and anti-inflammatory potential. We believe that with an adequate consumption of n-3PUFA dietary saturated fat may not result in elevated blood lipid levels. Therefore, we critically evaluated the literature regarding saturated fat and blood lipid level, with an emphasis on the role of n-3PUFA on this relationship. Evidence from animal studies and few clinical trials lead to the hypothesis that there are beneficial or neutral effects of saturated fatty acids when combined with recommended levels of n-3PUFA in the diet. However, an intervention focusing on the background fat when the volunteers' diet is supplemented with n-3PUFA is yet to be done. Proving the authenticity of this hypothesis would mean a substantial change in public health messages regarding saturated fats and their health effects; and also a change in the strategies related to prevention of chronic cardiac and artery diseases. © 2013 Elsevier Ltd.

DOI 10.1016/j.mehy.2013.11.036
Citations Scopus - 1Web of Science - 2
Co-authors Manohar Garg
2014 Oreo KM, Gibson PG, Simpson JL, Wood LG, Mcdonald VM, Baines KJ, 'Sputum ADAM8 expression is increased in severe asthma and COPD', Clinical and Experimental Allergy, 44 342-352 (2014) [C1]

Background: Severe asthma and chronic obstructive pulmonary disease (COPD) are chronic inflammatory airway diseases in which the mechanisms are not fully understood. A disintegrin... [more]

Background: Severe asthma and chronic obstructive pulmonary disease (COPD) are chronic inflammatory airway diseases in which the mechanisms are not fully understood. A disintegrin and metalloproteinase domain 8 (ADAM8) is an enzyme expressed on most leucocytes and may be important for facilitating leucocyte migration in respiratory disease. Objective: To investigate ADAM8 mRNA and protein expression in asthma and COPD and its relationship between asthma severity and inflammatory phenotypes. Methods: Induced sputum was collected from 113 subjects with asthma (severe n = 31, uncontrolled n = 39 and controlled n = 35), 20 subjects with COPD and 21 healthy controls. Sputum ADAM8 mRNA expression was measured by qPCR, and soluble ADAM8 (sADAM8) protein was measured in the sputum supernatant by validated ELISA. Results: ADAM8 mRNA correlated with ADAM8 protein levels (r = 0.27, P < 0.01). ADAM8 mRNA (P = 0.004) and sADAM8 protein (P = 0.014) levels were significantly higher in both asthma and COPD compared with healthy controls. ADAM8 mRNA (P = 0.035) and sADAM8 protein (P = 0.002) levels were significantly higher in severe asthma compared with controlled asthma. Total inflammatory cell count (P < 0.01) and neutrophils (P < 0.01) were also elevated in severe asthmatic sputum. Although ADAM8 mRNA was significantly higher in eosinophilic and neutrophilic asthma (P < 0.001), sADAM8 did not differ between asthma inflammatory phenotypes. ADAM8 expression positively correlated with sputum total cell count and sputum neutrophils. Conclusions and Clinical Relevance: ADAM8 expression is increased in both severe asthma and COPD and associated with sputum total cell count and neutrophils. ADAM8 may facilitate neutrophil migration to the airways in severe asthma and COPD. © 2013 John Wiley & Sons Ltd.

DOI 10.1111/cea.12223
Citations Scopus - 1Web of Science - 1
Co-authors Katherine Baines, Jodie Simpson, Peter Gibson, Vanessa Mcdonald
2014 Scott HA, Jensen ME, Wood LG, 'Dietary interventions in asthma', Current Pharmaceutical Design, 20 1003-1010 (2014) [C1]

Asthma is a chronic inflammatory disorder of the airways. The inflammatory response in asthma is heterogeneous. Allergen specific responses lead to activation of the acquired immu... [more]

Asthma is a chronic inflammatory disorder of the airways. The inflammatory response in asthma is heterogeneous. Allergen specific responses lead to activation of the acquired immune system, via a predominantly IL-5 mediated, eosinophilic pathway. Stimuli such as viruses and bacteria activate the innate immune system, via a predominantly IL-8 mediated, neutrophilic pathway. Asthma has also been demonstrated to involve a systemic inflammatory component. Glucocorticoids are the predominant pharmacological treatment used to control inflammation in asthma. However, compliance with medications can be compromised due to patient concerns about side effects. Hence dietary interventions that target the inflammatory response in asthma have great potential. Various aspects of dietary intake are known to modulate inflammation. Saturated fatty acids can induce an inflammatory response via activation of pattern recognition receptors. Omega-3 fatty acids can be anti-inflammatory, via mechanisms such as modification of eicosanoid production. Antioxidants can have anti-inflammatory effects as they scavenge free radicals, preventing activation of transcription factors including NF-¿B. Chronic excess energy intake can lead to obesity, which augments inflammation due to the release of inflammatory mediators by adipose tissue. Here we review the role of these dietary components in asthma. © 2014 Bentham Science Publishers.

DOI 10.2174/13816128113190990421
Citations Scopus - 4Web of Science - 5
Co-authors Hayley Scott
2014 Jameel F, Phang M, Wood LG, Garg ML, 'Acute effects of feeding fructose, glucose and sucrose on blood lipid levels and systemic inflammation.', Lipids in Health and Disease, 13 1-7 (2014) [C1]
DOI 10.1186/1476-511x-13-195
Co-authors Manohar Garg
2014 Baines KJ, Simpson JL, Wood LG, Scott RJ, Fibbens NL, Powell H, et al., 'Sputum gene expression signature of 6 biomarkers discriminates asthma inflammatory phenotypes', Journal of Allergy and Clinical Immunology, 133 997-1007 (2014) [C1]

Background Airway inflammation is associated with asthma exacerbation risk, treatment response, and disease mechanisms. Objective This study aimed to identify and validate a sputu... [more]

Background Airway inflammation is associated with asthma exacerbation risk, treatment response, and disease mechanisms. Objective This study aimed to identify and validate a sputum gene expression signature that discriminates asthma inflammatory phenotypes. Methods An asthma phenotype biomarker discovery study generated gene expression profiles from induced sputum of 47 asthmatic patients. A clinical validation study (n = 59 asthmatic patients) confirmed differential expression of key genes. A 6-gene signature was identified and evaluated for reproducibility (n = 30 asthmatic patients and n = 20 control subjects) and prediction of inhaled corticosteroid (ICS) response (n = 71 asthmatic patients). Receiver operating characteristic curves were calculated, and area under the curve (AUC) values were reported. Results From 277 differentially expressed genes between asthma inflammatory phenotypes, we identified 23 genes that showed highly significant differential expression in both the discovery and validation populations. A signature of 6 genes, including Charcot-Leydon crystal protein (CLC); carboxypeptidase A3 (CPA3); deoxyribonuclease I-like 3 (DNASE1L3); IL-1ß (IL1B); alkaline phosphatase, tissue-nonspecific isozyme (ALPL); and chemokine (C-X-C motif) receptor 2 (CXCR2), was reproducible and could significantly (P <.0001) discriminate eosinophilic asthma from other phenotypes, including patients with noneosinophilic asthma (AUC, 89.6%), paucigranulocytic asthma (AUC, 92.6%), or neutrophilic asthma (AUC, 91.4%) and healthy control subjects (AUC, 97.6%), as well as discriminating patients with neutrophilic asthma from those with paucigranulocytic asthma (AUC, 85.7%) and healthy control subjects (AUC, 90.8). The 6-gene signature predicted ICS response (>12% change in FEV1; AUC, 91.5%). ICS treatment reduced the expression of CLC, CPA3, and DNASE1L3 in patients with eosinophilic asthma. Conclusions A sputum gene expression signature of 6 biomarkers reproducibly and significantly discriminates inflammatory phenotypes of asthma and predicts ICS treatment response. This signature has the potential to become a useful diagnostic tool to assist in the clinical diagnosis and management of asthma. © 2013 American Academy of Allergy, Asthma & Immunology.

DOI 10.1016/j.jaci.2013.12.1091
Citations Scopus - 13Web of Science - 15
Co-authors Peter Gibson, Rodney Scott, Katherine Baines, Jodie Simpson
2013 Jensen ME, Wood LG, Williams RB, Collins CE, 'Associations between sleep, dietary intake and physical activity in children: systematic review', JBI Database of Systematic Reviews and Implementation Reports, 11 227-262 (2013) [C1]
Co-authors Clare Collins
2013 Grieger JA, Wood LG, Clifton VL, 'Improving asthma during pregnancy with dietary antioxidants: The current evidence', Nutrients, 5 3212-3234 (2013) [C1]

The complication of asthma during pregnancy is associated with a number of poor outcomes for the mother and fetus. This may be partially driven by increased oxidative stress induc... [more]

The complication of asthma during pregnancy is associated with a number of poor outcomes for the mother and fetus. This may be partially driven by increased oxidative stress induced by the combination of asthma and pregnancy. Asthma is a chronic inflammatory disease of the airways associated with systemic inflammation and oxidative stress, which contributes to worsening asthma symptoms. Pregnancy alone also intensifies oxidative stress through the systemic generation of excess reactive oxidative species (ROS). Antioxidants combat the damaging effects of ROS; yet antioxidant defenses are reduced in asthma. Diet and nutrition have been postulated as potential factors to combat the damaging effects of asthma. In particular, dietary antioxidants may play a role in alleviating the heightened oxidative stress in asthma. Although there are some observational and interventional studies that have shown protective effects of antioxidants in asthma, assessment of antioxidants in pregnancy are limited and there are no antioxidant intervention studies in asthmatic pregnancies on asthma outcomes. The aims of this paper are to (i) review the relationships between oxidative stress and dietary antioxidants in adults with asthma and asthma during pregnancy, and (ii) provide the rationale for which dietary management strategies, specifically increased dietary antioxidants, might positively impact maternal asthma outcomes. Improving asthma control through a holistic antioxidant dietary approach might be valuable in reducing asthma exacerbations and improving asthma management during pregnancy, subsequently impacting perinatal health. © 2013 by the authors; licensee MDPI, Basel, Switzerland.

DOI 10.3390/nu5083212
Citations Scopus - 2Web of Science - 2
2013 Periyalil HA, Gibson PG, Wood LG, 'Immunometabolism in obese asthmatics: Are we there yet?', Nutrients, 5 3506-3530 (2013) [C1]

Obesity is now recognised as a worldwide epidemic. The recent International Association for the Study of Obesity/International Obesity Taskforce (IASO/IOTF) analysis estimates tha... [more]

Obesity is now recognised as a worldwide epidemic. The recent International Association for the Study of Obesity/International Obesity Taskforce (IASO/IOTF) analysis estimates that approximately 1.0 billion adults are currently overweight and a further 475 million are obese. Obesity has huge psychosocial impact with obese children and adolescents facing discrimination and stigmatization in many areas of their lives leading to body dissatisfaction, low self-esteem and depression. Indeed, obesity is recognised as an important risk factor for the development of several chronic diseases such as hypertension, cancer, asthma and metabolic syndrome. Chronic low grade systemic inflammation is considered as a hallmark of obesity and may possibly explain the link between obesity and chronic disease, in particular the increased incidence, prevalence and severity of asthma in obese individuals. There is now strong evidence for infiltration of immune and inflammatory cells into adipose tissue that drives systemic inflammation and subsequent end organ damage. In addition to adipocytes, the key adipose tissue resident immune cells are macrophages and mast cells. Immunometabolism, as an emerging field of investigation, explores the pivotal role of these immune cells in translating immunological changes to metabolic effects in obesity. Abundance of free fatty acids, along with other inflammatory cytokines shift the balance of metabolic homeostasis to pro-inflammatory status by influencing the development of inflammatory cell lineage, which, further exhibits distinct functional phenotypes. There is emerging evidence for macrophage activation and functional polarization of an anti-inflammatory M2 phenotype towards a pro-inflammatory M1 phenotype of macrophages in obese adipose tissue. Similarly, studies in both obese humans and murine models reveal the pathognomic presence of an increased number of mast cells in visceral adipose tissue. These suggest a possible contribution of mast cells to the unique metabolome of obese asthma. This review examines proposed multilevel interactions between metabolic and immune systems in obese asthmatics that underlie the negative effects of obesity and may offer significant therapeutic promise. © 2013 by the authors; licensee MDPI, Basel, Switzerland.

DOI 10.3390/nu5093506
Citations Scopus - 3Web of Science - 3
Co-authors Peter Gibson
2013 Ghavipour M, Saedisomeolia A, Djalali M, Sotoudeh G, Eshraghyan MR, Moghadam AM, Wood LG, 'Tomato juice consumption reduces systemic inflammation in overweight and obese females', British Journal of Nutrition, 109 2031-2035 (2013) [C1]

Tomatoes are the richest source of lycopene, a potent antioxidant. Tomato products improve antioxidant defences and reduce the risk of inflammatory diseases, at least partly, due ... [more]

Tomatoes are the richest source of lycopene, a potent antioxidant. Tomato products improve antioxidant defences and reduce the risk of inflammatory diseases, at least partly, due to the presence of lycopene. Lycopene, as an anti-inflammatory agent, prevents the production of inflammatory cytokines. Obesity is a chronic inflammatory condition in which the increased level of body fat leads to an increase in circulating inflammatory mediators. We hypothesised that the consumption of a lycopene-rich food would reduce inflammation in people who are overweight or obese. A total of 106 overweight or obese female students of the Tehran University of Medical Sciences were enrolled and randomly allocated to an intervention group (n 53) or a control group (n 53) consuming 330 ml/d of tomato juice or water, respectively, for 20 d. At baseline and day 20, serum concentrations of IL-6, IL-8, high-sensitivity C-reactive protein and TNF-a were analysed by ELISA and compared between the groups. Serum concentrations of IL-8 and TNF-a decreased significantly in the intervention group compared with the control group and with baseline. Subgroup analysis indicated that this effect was confined to subjects who were overweight. Among obese subjects, serum IL-6 concentration was decreased in the intervention group compared with the control group, with no differences in IL-8 and TNF-a observed. Tomato juice reduces inflammation in overweight and obese females. Thus, increasing tomato intake may provide a useful approach for reducing the risk of inflammatory diseases such as CVD and diabetes, which are associated with obesity. Copyright © 2012 The Authors.

DOI 10.1017/S0007114512004278
Citations Scopus - 12Web of Science - 9
2013 McDonald V, Wood L, Baines P, Higgins I, Gibson P, 'Obesity and bone health in COPD', EUROPEAN RESPIRATORY JOURNAL, 42 (2013)
Co-authors Isabel Higgins, Peter Gibson
2013 McDonald VM, Higgins I, Wood LG, Gibson PG, 'Multidimensional assessment and tailored interventions for COPD: respiratory utopia or common sense?', THORAX, 68 691-694 (2013) [C1]
DOI 10.1136/thoraxjnl-2012-202646
Citations Scopus - 19Web of Science - 18
Co-authors Vanessa Mcdonald, Isabel Higgins, Peter Gibson
2013 Jensen ME, Gibson PG, Collins CE, Wood LG, 'Airway and systemic inflammation in obese children with asthma', EUROPEAN RESPIRATORY JOURNAL, 42 1012-1019 (2013) [C1]
DOI 10.1183/09031936.00124912
Citations Scopus - 17Web of Science - 12
Co-authors Clare Collins, Peter Gibson
2013 Jensen ME, Gibson PG, Collins CE, Hilton JM, Wood LG, 'Diet-induced weight loss in obese children with asthma: a randomized controlled trial', CLINICAL AND EXPERIMENTAL ALLERGY, 43 775-784 (2013) [C1]
DOI 10.1111/cea.12115
Citations Scopus - 16Web of Science - 15
Co-authors Clare Collins, Peter Gibson
2013 Berthon BS, Macdonald-Wicks LK, Gibson PG, Wood LG, 'Investigation of the association between dietary intake, disease severity and airway inflammation in asthma', RESPIROLOGY, 18 447-454 (2013) [C1]
DOI 10.1111/resp.12015
Citations Scopus - 11Web of Science - 10
Co-authors Lesley Wicks, Peter Gibson
2013 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Dietary restriction and exercise improve airway inflammation and clinical outcomes in overweight and obese asthma: a randomized trial', Clinical and Experimental Allergy, 43 36-49 (2013) [C1]
DOI 10.1111/cea.12004
Citations Scopus - 28Web of Science - 24
Co-authors Peter Gibson, Philip Morgan, Manohar Garg, Robin Callister, Hayley Scott
2013 Jensen ME, Gibson PG, Collins CE, Hilton JM, Latham-Smith F, Wood LG, 'Increased sleep latency and reduced sleep duration in children with asthma', SLEEP AND BREATHING, 17 281-287 (2013) [C1]
DOI 10.1007/s11325-012-0687-1
Citations Scopus - 5Web of Science - 5
Co-authors Clare Collins, Peter Gibson
2013 Fu J-J, Baines KJ, Wood LG, Gibson PG, 'Systemic Inflammation Is Associated with Differential Gene Expression and Airway Neutrophilia in Asthma', OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY, 17 187-199 (2013) [C1]
DOI 10.1089/omi.2012.0104
Citations Scopus - 11Web of Science - 9
Co-authors Peter Gibson, Katherine Baines
2013 Fulton AS, Hill AM, Williams MT, Howe PR, Frith PA, Wood LG, et al., 'Feasibility of omega-3 fatty acid supplementation as an adjunct therapy for people with chronic obstructive pulmonary disease: study protocol for a randomized controlled trial', TRIALS, 14 (2013) [C3]
DOI 10.1186/1468-6708-14-107
Citations Scopus - 4Web of Science - 3
Co-authors Peter Howe, Manohar Garg
2012 Garg ML, Wood LG, 'Preface', Nutrition and Physical Activity in Inflammatory Diseases, (2012)
Co-authors Manohar Garg
2012 Wood LG, Garg ML, Smart JM, Scott HA, Barker D, Gibson PG, 'Manipulating antioxidant intake in asthma: A randomized controlled trial', American Journal of Clinical Nutrition, 96 534-543 (2012) [C1]
Citations Scopus - 28Web of Science - 28
Co-authors Manohar Garg, Peter Gibson, Hayley Scott
2012 Wood LG, Baines KJ, Fu J, Scott HA, Gibson PG, 'The neutrophilic inflammatory phenotype is associated with systemic inflammation in asthma', Chest, 142 86-93 (2012) [C1]
Citations Scopus - 50Web of Science - 44
Co-authors Peter Gibson, Katherine Baines, Hayley Scott
2012 McLernon PC, Wood LG, Murphy VE, Hodyl NA, Clifton VL, 'Circulating antioxidant profile of pregnant women with asthma', Clinical Nutrition, 31 99-107 (2012) [C1]
Citations Scopus - 7Web of Science - 6
Co-authors Vanessa Murphy, Vicki Clifton
2012 Sukkar MB, Wood LG, Tooze MK, Simpson JL, McDonald VM, Gibson PG, Wark PA, 'Soluble RAGE is deficient in neutrophilic asthma and COPD', European Respiratory Journal, 39 721-729 (2012) [C1]
Co-authors Peter Wark, Vanessa Mcdonald, Jodie Simpson, Peter Gibson
2012 Wood LG, Gibson PG, 'Adiponectin: The link between obesity and asthma in women?', American Journal of Respiratory and Critical Care Medicine, 186 1-2 (2012) [C3]
Citations Scopus - 5Web of Science - 3
Co-authors Peter Gibson
2012 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Relationship between body composition, inflammation and lung function in overweight and obese asthma', Respiratory Research, 13 1-10 (2012) [C1]
Citations Scopus - 11Web of Science - 9
Co-authors Peter Gibson, Hayley Scott, Manohar Garg, Philip Morgan, Robin Callister
2012 Jensen ME, Wood LG, Gibson PG, 'Obesity and childhood asthma - Mechanisms and manifestations', Current Opinion in Allergy and Clinical Immunology, 12 186-192 (2012) [C1]
Citations Scopus - 26Web of Science - 25
Co-authors Peter Gibson
2012 McLernon PC, Wood LG, Murphy VE, Hodyl NA, Clifton VL, 'Fatty acid profile of pregnant women with asthma', e-SPEN Journal, 7 e78-e85 (2012) [C1]
DOI 10.1016/j.clnme.2012.01.004
Co-authors Vanessa Murphy, Vicki Clifton
2011 Jensen ME, Collins CE, Gibson PG, Wood LG, 'The obesity phenotype in children with asthma', Paediatric Respiratory Reviews, 12 152-159 (2011) [C1]
DOI 10.1016/j.prrv.2011.01.009
Citations Scopus - 17Web of Science - 19
Co-authors Peter Gibson, Clare Collins
2011 Baines KJ, Simpson JL, Wood LG, Scott R, Gibson PG, 'Systemic upregulation of neutrophil a-defensins and serine proteases in neutrophilic asthma', Thorax, 66 942-947 (2011) [C1]
Citations Scopus - 17Web of Science - 16
Co-authors Peter Gibson, Jodie Simpson, Rodney Scott, Katherine Baines
2011 Wood LG, Garg ML, Gibson PG, 'A high-fat challenge increases airway inflammation and impairs bronchodilator recovery in asthma', Journal of Allergy and Clinical Immunology, 127 1133-1140 (2011) [C1]
DOI 10.1016/j.jaci.2011.01.036
Citations Scopus - 45Web of Science - 38
Co-authors Manohar Garg, Peter Gibson
2011 Baines KJ, Simpson JL, Wood LG, Scott R, Gibson PG, 'Transcriptional phenotypes of asthma defined by gene expression profiling of induced sputum samples', Journal of Allergy and Clinical Immunology, 127 153.e9-160.e9 (2011) [C1]
DOI 10.1016/j.jaci.2010.10.024
Citations Scopus - 69Web of Science - 59
Co-authors Katherine Baines, Peter Gibson, Jodie Simpson, Rodney Scott
2011 Phang M, Lazarus S, Wood LG, Garg ML, 'Diet and thrombosis risk: Nutrients for prevention of thrombotic disease', Seminars in Thrombosis and Hemostasis, 37 199-208 (2011) [C1]
DOI 10.1055/s-0031-1273084
Citations Scopus - 26Web of Science - 22
Co-authors Manohar Garg
2011 Scott HA, Gibson PG, Garg ML, Wood LG, 'Airway inflammation is augmented by obesity and fatty acids in asthma', European Respiratory Journal, 38 594-602 (2011) [C1]
Citations Scopus - 70Web of Science - 63
Co-authors Hayley Scott, Manohar Garg, Peter Gibson
2011 Wood LG, Simpson JL, Wark PA, Powell H, Gibson PG, 'Characterization of innate immune signalling receptors in virus-induced acute asthma', Clinical and Experimental Allergy, 41 640-648 (2011) [C1]
DOI 10.1111/j.1365-2222.2010.03669.x
Citations Scopus - 14Web of Science - 13
Co-authors Peter Wark, Peter Gibson, Jodie Simpson
2011 Hazlewood LC, Wood LG, Hansbro PM, Foster PS, 'Dietary lycopene supplementation suppresses Th2 responses and lung eosinophilia in a mouse model of allergic asthma', Journal of Nutritional Biochemistry, 22 95-100 (2011) [C1]
DOI 10.1016/j.jnutbio.2009.12.003
Citations Scopus - 18Web of Science - 15
Co-authors Philip Hansbro, Paul Foster
2011 Verrills NM, Irwin JA, He XY, Wood LG, Powell H, Simpson JL, et al., 'Identification of novel diagnostic biomarkers for asthma and chronic obstructive pulmonary disease', American Journal of Respiratory and Critical Care Medicine, 183 1633-1643 (2011) [C1]
DOI 10.1164/rccm.201010-1623OC
Citations Scopus - 37Web of Science - 34
Co-authors Vanessa Mcdonald, Jodie Simpson, Nikki Verrills, Peter Gibson, Alistair Sim
2011 Wood LG, Powell H, Grissell TV, Davies BL, Shafren DR, Whitehead BF, et al., 'Persistence of rhinovirus RNA and IP-10 gene expression after acute asthma', Respirology, 16 291-299 (2011) [C1]
DOI 10.1111/j.1440-1843.2010.01897.x
Citations Scopus - 9Web of Science - 9
Co-authors Peter Gibson, Michael Hensley
2010 Wood LG, Wark PA, Garg ML, 'Antioxidant and anti-inflammatory effects of resveratrol in airway disease', Antioxidants & Redox Signaling, 13 1535-1548 (2010) [C1]
DOI 10.1089/ars.2009.3064
Citations Scopus - 43Web of Science - 42
Co-authors Manohar Garg, Peter Wark
2010 Garg ML, Wood LG, 'Functional foods and cardiovascular disease', Cardiology in General Practice, 14 24-25 (2010) [C2]
Co-authors Manohar Garg
2010 Wood LG, Gibson PG, 'Reduced circulating antioxidant defences are associated with airway hyper-responsiveness, poor control and severe disease pattern in asthma', British Journal of Nutrition, 103 735-741 (2010) [C1]
DOI 10.1017/s0007114509992376
Citations Scopus - 14Web of Science - 16
Co-authors Peter Gibson
2010 Wood LG, Attia JR, McElduff P, McEvoy MA, Gibson PG, 'Assessment of dietary fat intake and innate immune activation as risk factors for impaired lung function', European Journal of Clinical Nutrition, 64 818-825 (2010) [C1]
DOI 10.1038/ejcn.2010.68
Citations Scopus - 5Web of Science - 5
Co-authors John Attia, Patrick Mcelduff, Peter Gibson
2010 Wood LG, Hazlewood LC, Foster PS, Hansbro PM, 'Lyprinol reduces inflammation and improves lung function in a mouse model of allergic airways disease', Clinical and Experimental Allergy, 40 1785-1793 (2010) [C1]
DOI 10.1111/j.1365-2222.2010.03503.x
Citations Scopus - 10Web of Science - 8
Co-authors Paul Foster, Philip Hansbro
2010 Wood LG, Simpson JL, Hansbro PM, Gibson PG, 'Potentially pathogenic bacteria cultured from the sputum of stable asthmatics are associated with increased 8-isoprostane and airway neutrophilia', Free Radical Research, 44 146-154 (2010) [C1]
DOI 10.3109/10715760903362576
Citations Scopus - 23Web of Science - 18
Co-authors Peter Gibson, Philip Hansbro, Jodie Simpson
2010 Wood LG, Powell HG, Gibson PG, 'Mannitol challenge for assessment of airway responsiveness, airway inflammation and inflammatory phenotype in asthma', Clinical & Experimental Allergy, 40 232-241 (2010) [C1]
DOI 10.1111/j.1365-2222.2009.03371.x
Citations Scopus - 21Web of Science - 17
Co-authors Peter Gibson
2009 Baines KJ, Wood LG, Gibson PG, 'The nutrigenomics of asthma: Molecular mechanisms of airway neutrophilia following dietary antioxidant withdrawal', OMICS: A Journal of Integrative Biology, 13 355-365 (2009) [C1]
DOI 10.1089/omi.2009.0042
Citations Scopus - 13Web of Science - 11
Co-authors Katherine Baines, Peter Gibson
2009 Saedi Some Olia A, Wood LG, Garg ML, Gibson PG, Wark PA, 'Anti-inflammatory effects of long-chain n-3 PUFA in rhinovirus-infected cultured airway epithelial cells', British Journal of Nutrition, 101 533-540 (2009) [C1]
DOI 10.1017/s0007114508025798
Citations Scopus - 14Web of Science - 12
Co-authors Manohar Garg, Peter Gibson, Peter Wark
2009 Wood LG, Gibson PG, 'Dietary factors lead to innate immune activation in asthma', Pharmacology and Therapeutics, 123 37-53 (2009) [C1]
DOI 10.1016/j.pharmthera.2009.03.015
Citations Scopus - 31Web of Science - 29
Co-authors Peter Gibson
2009 Wood LG, Scott HA, Garg ML, Gibson PG, 'Innate immune mechanisms linking non-esterified fatty acids and respiratory disease', Progress in Lipid Research, 48 27-43 (2009) [C1]
DOI 10.1016/j.plipres.2008.10.001
Citations Scopus - 23Web of Science - 18
Co-authors Peter Gibson, Manohar Garg, Hayley Scott
2009 Saedi Some Olia A, Wood LG, Garg ML, Gibson PG, Wark PA, 'Lycopene enrichment of cultured airway epithelial cells decreases the inflammation induced by rhinovirus infection and lipopolysaccharide', Journal of Nutritional Biochemistry, 20 577-585 (2009) [C1]
DOI 10.1016/j.jnutbio.2008.06.001
Citations Scopus - 27Web of Science - 25
Co-authors Peter Gibson, Manohar Garg, Peter Wark
2008 Saedi Some Olia A, Wood LG, Garg ML, Gibson PG, Wark PA, 'Supplementation of long chain N-3 polyunsaturated fatty acids increases the utilization of lycopene in cultured airway epithelial cells', Journal of Food Lipids, 15 421-432 (2008) [C1]
DOI 10.1111/j.1745-4522.2008.00130.x
Citations Scopus - 5Web of Science - 3
Co-authors Peter Gibson, Peter Wark, Manohar Garg
2008 Wood LG, Garg ML, Powell H, Gibson PG, 'Lycopene-rich treatments modify noneosinophilic airway inflammation in asthma: Proof of concept', Free Radical Research, 42 94-102 (2008) [C1]
DOI 10.1080/10715760701767307
Citations Scopus - 37Web of Science - 38
Co-authors Manohar Garg, Peter Gibson
2008 Powell H, Smart JM, Wood LG, Grissell TV, Shafren DR, Hensley MJ, Gibson PG, 'Validity of the common cold questionnaire (CCQ) in asthma exacerbations', PLoS ONE, 3 e1802 (2008) [C1]
DOI 10.1371/journal.pone.0001802
Co-authors Michael Hensley, Peter Gibson
2008 Wood LG, Garg ML, Blake RJ, Simpson JL, Gibson PG, 'Oxidized vitamin E and glutathione as markers of clinical status in asthma', Clinical Nutrition, 27 579-586 (2008) [C1]
DOI 10.1016/j.clnu.2007.12.002
Citations Scopus - 17Web of Science - 14
Co-authors Peter Gibson, Manohar Garg, Jodie Simpson
2007 Wood LG, Powell HG, Grissell TV, Nguyen TTD, Shafren D, Hensley MJ, Gibson PG, 'Persistent airway obstruction after virus infection is not associated with airway inflammation', Chest, 131 415-423 (2007) [C1]
DOI 10.1378/chest.06-1062
Citations Scopus - 8Web of Science - 7
Co-authors Michael Hensley, Peter Gibson
2006 Garg ML, Wood LG, Singh H, Moughan PJ, 'Means of delivering recommended levels of long chain n-3 polyunsaturated fatty acids in human diets', Journal of Food Science, 71 R66-R71 (2006) [C1]
DOI 10.1111/j.1750-3841.2006.00033.x
Citations Scopus - 78Web of Science - 57
Co-authors Manohar Garg
2006 MacDonald-Wicks LK, Wood LG, Garg ML, 'Methodology for the determination of biological antioxidant capacity in vitro: A review', Journal of the Science of Food and Agriculture, 86 2046-2056 (2006) [C1]
DOI 10.1002/jsfa.2603
Citations Scopus - 130Web of Science - 100
Co-authors Lesley Wicks, Manohar Garg
2006 Wood LG, Gibson PG, Garg ML, 'A review of the methodology for assessing in vivo antioxidant capacity', Journal of the Science of Food and Agriculture, 86 2057-2066 (2006) [C1]
DOI 10.1002/jsfa.2604
Citations Scopus - 51Web of Science - 39
Co-authors Peter Gibson, Manohar Garg
2005 Wood LG, Gibson PG, Garg ML, 'Circulating markers to assess nutritional therapy in cystic fibrosis', Clinica Chimica Acta, 353 13-29 (2005) [C1]
DOI 10.1016/j.cccn.2004.11.002
Citations Scopus - 7Web of Science - 6
Co-authors Manohar Garg, Peter Gibson
2005 Wood LG, Garg ML, Blake RJ, Garcia-Caraballo S, Gibson PG, 'Airway and Circulating Levels of Carotenoids in Asthma and Healthy Controls', Journal of the American College of Nutrition, 24 448-455 (2005) [C1]
Citations Scopus - 34Web of Science - 30
Co-authors Peter Gibson, Manohar Garg
2005 Simpson JL, Wood LG, Gibson PG, 'Inflammatory mediators in exhaled breath, induced sputum and saliva', Clinical & Experimental Allergy, 35 1180-1185 (2005) [C1]
DOI 10.1111/j.1365-2222.2005.02327.x
Citations Scopus - 41Web of Science - 39
Co-authors Peter Gibson, Jodie Simpson
2005 Wood LG, Garg ML, Simpson JL, Mori TA, Croft KD, Wark PA, Gibson PG, 'Induced sputum 8-isoprostane concentrations in inflammatory airway diseases', American Journal of Respiratory and Critical Care Medicine, 171 426-430 (2005) [C1]
DOI 10.1164/rccm.200408-1010OC
Citations Scopus - 58Web of Science - 51
Co-authors Jodie Simpson, Manohar Garg, Peter Gibson, Peter Wark
2003 Wood LG, Fitzgerald DA, Lee AK, Garg ML, 'Improved antioxidant and fatty acid status of patients with cystic-fibrosis after antioxidant supplementation is linked to improved lung function', American Journal of Clinical Nutrition, 77 150-159 (2003) [C1]
Citations Scopus - 60Web of Science - 58
Co-authors Manohar Garg
2003 Wood LG, Fitzgerald DA, Garg ML, 'Hypothesis: Vitamin E complements polyunsaturated fatty acids in essential fatty acid defiency in cystic fibrosis', American College of Nutrition Journal, 22 253-256 (2003) [C1]
Citations Scopus - 10Web of Science - 10
Co-authors Manohar Garg
2003 Wood LG, Gibson PG, Garg ML, 'Exhaled breath condensate contains more than only volatiles', The European Respiratory Journal, 22 1 (2003) [C3]
Citations Scopus - 5
Co-authors Manohar Garg, Peter Gibson
2002 Wood LG, Fitzgerald DA, Gibson PG, Cooper DM, Garg ML, 'Increased plasma fatty acid concentrations after respiratory exacerbations are associated with elevated oxidative stress in cystic fibrosis patients', American Journal of Clinical Nutrition: a journal reporting the practical application of our world-wide knowledge of nutrition, 75 668-675 (2002) [C1]
Citations Scopus - 34Web of Science - 30
Co-authors Manohar Garg, Peter Gibson
2001 Wood L, Fitzgerald D, Gibson PG, Cooper D, Collins C, Garg M, 'Oxidative Stress in Cystic Fibrosis: Dietary and Metabolic Factors', Journal of the American College of Nutrition, 20 157-165 (2001) [C1]
Citations Scopus - 60Web of Science - 50
Co-authors Clare Collins, Manohar Garg, Peter Gibson
2000 Wood LG, Fitzgerald DA, Gibson PG, Cooper DM, Garg ML, 'Lipid Peroxidation as Determined by Plasma Isoprostanes Is Related to Disease Severity in Mild Asthma', Lipids, 35;9 967-974 (2000) [C1]
Citations Scopus - 114Web of Science - 100
Co-authors Peter Gibson, Manohar Garg
1999 Fitzgerald DA, Wood LG, Cooper DM, Gibson PG, Garg ML, 'Isoprostanes and antioxidant defences in cystic fibrosis', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 159 A682-A682 (1999)
Co-authors Peter Gibson, Manohar Garg
Show 88 more journal articles

Review (1 outputs)

Year Citation Altmetrics Link
2003 Wood LG, Gibson PG, Garg ML, 'Biomarkers of lipid peroxidation, airway inflammation and asthma', The European Respiratory Journal (2003) [D2]
Citations Scopus - 156Web of Science - 145
Co-authors Peter Gibson, Manohar Garg

Conference (119 outputs)

Year Citation Altmetrics Link
2014 Horvat J, Kim R, Mayall J, Pinkerton J, Starkey M, Essilfie A, et al., 'ANTIOXIDANT-BASED THERAPY FOR THE SUPPRESSION OF EARLY- LIFE INFECTION-INDUCED SEVERE ASTHMA', RESPIROLOGY (2014) [E3]
DOI 10.1111/resp.12263_2
Co-authors Philip Hansbro, Jay Horvat, Malcolm Starkey
2014 Fathi F, Hsu A, Parsons K, Keely S, Wood L, Wark P, 'OXIDATIVE STRESS IMPAIRS MITOCHONDRIAL FUNCTION AND LEADS TO DEFICIENT ANTIVIRAL RESPONSES IN PRIMARY BRONCHIAL EPITHELIAL CELLS', RESPIROLOGY (2014) [E3]
DOI 10.1111/resp.12263_3
Co-authors Alan Hsu, Simon Keely, Peter Wark
2014 Periyalil H, Scott H, Jensen M, Wood L, Gibson P, 'MACROPHAGE ACTIVATION IS A DETERMINANT OF DEVELOPMENTAL EFFECTS OF IMMUNOMETABOLISM IN OBESE ASTHMA', RESPIROLOGY (2014) [E3]
DOI 10.1111/resp.12263_7
Co-authors Hayley Scott, Peter Gibson
2014 Berthon B, Macdonald-Wicks L, Gibson P, Wood L, 'SHORT TERM ORAL CORTICOSTEROID THERAPY DOES NOT INCREASE APPETITE, DIETARY INTAKE, BODY WEIGHT AND BODY COMPOSITION IN ADULTS WITH ASTHMA - A RANDOMIZED-CONTROLLED TRIAL', RESPIROLOGY (2014) [E3]
Co-authors Peter Gibson, Lesley Wicks
2014 Wright T, Gibson P, Simpson J, Mcdonald V, Wood L, Baines K, 'ALARMINS IN ASTHMA AND COPD: RELATIONSHIPS TO INFLAMMATORY PHENOTYPES AND DISEASE SEVERITY', RESPIROLOGY (2014) [E3]
Co-authors Katherine Baines, Jodie Simpson, Peter Gibson, Vanessa Mcdonald
2014 Baines K, Simpson J, Wood L, Scott R, Fibbens N, Powell H, et al., 'SPUTUM GENE EXPRESSION OF SIX MARKERS IDENTIFIES ASTHMA INFLAMMATORY PHENOTYPE AND CORTICOSTEROID RESPONSE', RESPIROLOGY (2014) [E3]
Co-authors Rodney Scott, Jodie Simpson, Katherine Baines
2014 Wood L, Shivappa N, Berthon B, Gibson P, Hebert J, 'DIETARY INFLAMMATORY INDEX IS RELATED TO ASTHMA RISK, LUNG FUNCTION AND SYSTEMIC INFLAMMATION IN ASTHMA', RESPIROLOGY (2014) [E3]
Citations Web of Science - 1
Co-authors Peter Gibson
2014 Mcdonald V, Gibson P, Scott H, Baines P, Hensley M, Pretto J, Wood L, 'SHOULD WE TREAT OBESITY IN COPD? THE EFFECTS OF WEIGHT LOSS AND RESISTANCE TRAINING IN OBESE COPD', RESPIROLOGY (2014) [E3]
Co-authors Vanessa Mcdonald, Hayley Scott, Michael Hensley, Peter Gibson
2013 Scott HA, Gibson PG, Garg ML, Smart J, Wood LG, 'Female Reproductive Stage Drives The Association Between Obesity And Neutrophilic Airway Inflammation In Adults With Asthma', American Journal of Respiratory and Critical Care Medicine, Philadelphia, PA (2013) [E3]
Co-authors Hayley Scott, Peter Gibson, Manohar Garg
2013 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'The Association Between Obesity and Asthma is Driven By Female Reproductive Stage', Australasian Medical Journal, Brisbane (2013) [E3]
Co-authors Hayley Scott, Peter Gibson, Manohar Garg
2013 Williams R, Wood L, Collins CE, Callister R, 'Energy and appetite regulating hormones: do they differ between males and females?', Australasian Medical Journal, Brisbane, Australia (2013) [E3]
Co-authors Robin Callister, Clare Collins
2013 Callister R, Williams R, Wood L, Morgan P, Collins CE, 'Energy and appetite regulating hormones: Sex and weight category differences prior to weight loss', Obesity Research and Clinical Practice, Melbourne, Australia (2013) [E3]
Co-authors Philip Morgan, Robin Callister, Clare Collins
2013 Berthon B, MacDonald-Wicks L, Gibson P, Wood L, 'Changes in body composition are associated with corticosteroid use in adult asthma', EUROPEAN RESPIRATORY JOURNAL (2013)
Co-authors Peter Gibson, Lesley Wicks
2013 Scott HA, Gibson PG, Garg ML, Smart J, Wood LG, 'REPRODUCTIVE STAGE DRIVES LINK BETWEEN OBESITY AND NEUTROPHILIC AIRWAY INFLAMMATION IN FEMALES WITH ASTHMA', RESPIROLOGY (2013) [E3]
Co-authors Hayley Scott, Peter Gibson, Manohar Garg
2013 Berthon BS, Macdonald-Wicks LK, Gibson PG, Wood LG, 'PARTIAL OR POOR ASTHMA CONTROL IS RELATED TO ANXIETY AND DEPRESSION SCORES', RESPIROLOGY (2013) [E3]
Co-authors Lesley Wicks, Peter Gibson
2013 Zhong H, Simpson JL, Wood LG, Wark PAB, 'COPD PERIPHERAL BLOOD NEUTROPHILS HAVE ENHANCED RELEASE OF IL-1B WHEN STIMULATED', RESPIROLOGY (2013) [E3]
Co-authors Peter Wark, Jodie Simpson
2013 Mcdonald VM, Wood LG, Baines P, Higgins I, Gibson PG, 'OBESITY IN COPD PROTECTIVE FOR OSTEOPOROSIS?', RESPIROLOGY (2013) [E3]
Co-authors Isabel Higgins, Peter Gibson, Vanessa Mcdonald
2013 Dias C, Wood LG, Phang M, Garg ML, 'Omega-3 polyunsaturated fatty acids alleviate dietary saturated fat-induced postprandial rise in blood lipid levels', Nutrients, Newcastle (2013) [E3]
DOI 10.3390/nu5125065
Co-authors Manohar Garg
2012 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Female reproductive stage drives the association between obesity and neutrophilic airway inflammation in adults with asthma', Abstracts. American Thoracic Society 2012 International Conference, San Francisco, CA (2012) [E3]
Co-authors Peter Gibson, Manohar Garg, Hayley Scott
2012 Jensen ME, Gibson PG, Collins CE, Wood LG, 'Distribution of lean and fat mass differentially affect lung function in children', Abstracts. American Thoracic Society 2012 International Conference, San Francisco, CA (2012) [E3]
Co-authors Clare Collins, Peter Gibson
2012 Jensen ME, Gibson PG, Collins CE, Wood LG, 'Systemic inflammation and clinical asthma outcomes in obese and non-obese children: A cross-sectional study', Abstracts. American Thoracic Society 2012 International Conference, San Francisco, CA (2012) [E3]
Co-authors Clare Collins, Peter Gibson
2012 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Reproductive stage drives link between obesity and neutrophilic airway inflammation in females with asthma', Abstracts. TSANZ Annual Scientific Meeting 2012, Canberra, ACT (2012) [E3]
Co-authors Manohar Garg, Peter Gibson, Hayley Scott
2012 Addnan FH, Wood LG, Garg ML, Wark PA, 'Antiviral effects of antioxidants on human rhinovirus', Respirology, Canberra, ACT (2012) [E3]
Co-authors Peter Wark, Manohar Garg
2012 McDonald VM, Wark PA, Roberts M, Spencer LM, Alison JA, Wood LG, Gibson PG, 'Development and audience testing of a COPD education DVD', Respirology, Canberra, ACT (2012) [E3]
Co-authors Peter Gibson, Peter Wark, Vanessa Mcdonald
2012 Zhong H, Simpson JL, Wood LG, Wark PA, 'Activation of human neutrophils exposed to cigarette smoke extract: A comparison of COPD patients versus healthy non-smokers', Respirology, Canberra, ACT (2012) [E3]
Co-authors Jodie Simpson, Peter Wark
2012 Wood LG, Garg ML, Smart JM, Scott HA, Barker D, Gibson PG, 'Manipulating antioxidant intake in asthma: A randomized clinical trial', Respirology, Canberra, ACT (2012) [E3]
Citations Web of Science - 2
Co-authors Hayley Scott, Manohar Garg, Peter Gibson
2012 Zhong H, Simpson JL, Wood LG, Wark PA, 'Different responses of blood neutrophils from COPD', Respirology, Hong Kong (2012) [E3]
Co-authors Jodie Simpson, Peter Wark
2012 Baines KJ, Simpson JL, Wood LG, Scott RJ, Gibson PG, 'Sputum gene expression of mast cell specific proteases are increased in eosinophilic asthma', Respirology, Canberra, ACT (2012) [E3]
Co-authors Jodie Simpson, Peter Gibson, Rodney Scott, Katherine Baines
2012 Baines KJ, Simpson JL, Wood LG, Scott RJ, Gibson PG, 'Induced sputum differential gene expression implicates increased p38 signalling activity in severe asthma', Respirology, Canberra, ACT (2012) [E3]
Co-authors Katherine Baines, Jodie Simpson, Rodney Scott, Peter Gibson
2012 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Weight loss improves clinical asthma outcomes and airway inflammation in overweight and obese asthmatics', Obesity Research & Clinical Practice, Auckland, New Zealand (2012) [E3]
Co-authors Philip Morgan, Robin Callister, Hayley Scott, Peter Gibson, Manohar Garg
2011 Addnan FH, Wark PA, Wood LG, Garg ML, 'Antiviral activity of antioxidants against rhinovirus infection', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
Co-authors Manohar Garg, Peter Wark
2011 Berthon B, MacDonald-Wicks LK, Gibson PG, Wood LG, 'Asthmatics have an altered eating pattern with increased fat and decreased fibre intake associated with airway inflammation and poorer lung function', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
Co-authors Lesley Wicks, Peter Gibson
2011 Addnan FH, Wark PA, Wood LG, Garg ML, 'Effects of antioxidants on inflammation and apoptosis in rhinovirus-infected airway epithelial cells', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
Co-authors Peter Wark, Manohar Garg
2011 Berthon B, MacDonald-Wicks LK, Gibson PG, Wood LG, 'Plasma leptin levels are elevated in stable asthma', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
Co-authors Peter Gibson, Lesley Wicks
2011 Berthon B, MacDonald-Wicks LK, Wood LG, 'A systematic review of corticosteroid use, dietary intake and body weight in adults', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
Co-authors Lesley Wicks
2011 Jensen ME, Collins CE, Gibson PG, Hilton JM, Wood LG, 'Dietary induced weight loss improves asthma control and lung function after 10 weeks in obese children and adolescents with asthma', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
Co-authors Clare Collins, Peter Gibson
2011 Jensen ME, Gibson PG, Collins CE, Wood LG, 'Lean mass is positively associated with respiratory function in male asthmatic children', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
Co-authors Peter Gibson, Clare Collins
2011 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'The influence of body composition and inflammation on lung function in asthma', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
Co-authors Philip Morgan, Robin Callister, Manohar Garg, Peter Gibson, Hayley Scott
2011 Smart JM, Wark PA, Wood LG, 'Investigating the obesity paradox in ex-smokers', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
Co-authors Peter Wark
2011 Clifton VL, McLernon PC, Wood LG, Murphy VE, Stark MJ, Hodyl NA, 'What do women eat during pregnancy?', Journal of Developmental Origins of Health and Disease, Portland, Oregon (2011) [E3]
Co-authors Vanessa Murphy
2011 Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Systemic upregulation of neutrophil a-defensins and serine proteases in neutrophilic asthma', European Respiratory Society Annual Congress 2011 Abstracts, Amsterdam (2011) [E3]
Co-authors Rodney Scott, Katherine Baines, Jodie Simpson, Peter Gibson
2011 Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Sputum gene expression of mast cell tryptase and carboxypeptidase A3 are increased in eosinophilic asthma', European Respiratory Society Annual Congress 2011 Abstracts, Amsterdam (2011) [E3]
Co-authors Katherine Baines, Rodney Scott, Jodie Simpson, Peter Gibson
2011 Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Induced sputum differential gene expression implicates increased p38 signalling activity in severe asthma', European Respiratory Society Annual Congress 2011 Abstracts, Amsterdam (2011) [E3]
Co-authors Peter Gibson, Jodie Simpson, Rodney Scott, Katherine Baines
2011 Clifton V, McLernon P, Wood LG, Murphy VE, Hodyl N, 'What do pregnant women eat?', Placenta: Abstracts of the IFPA Meeting 2011, Geilo, Norway (2011) [E3]
Co-authors Vanessa Murphy
2011 Jensen ME, Collins CE, Gibson PG, Hilton JM, Wood LG, 'Characterising the obese phenotype in asthmatic children and adolescents', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
Co-authors Clare Collins, Peter Gibson
2011 Jensen ME, Gibson PG, Collins CE, Hilton JM, Latham-Smith F, Wood LG, 'Gender differences in sleep duration & sleep quality in children with & without asthma using polysomnography', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
Co-authors Clare Collins, Peter Gibson
2011 Jensen ME, Gibson PG, Collins CE, Hilton JM, Wood LG, 'Results from a ten week pilot weight loss intervention in obese asthmatic children and adolescents', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
Co-authors Clare Collins, Peter Gibson
2011 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Clinical asthma outcomes are improved after body fat reduction in overweight and obese asthmatics', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
Co-authors Peter Gibson, Hayley Scott, Manohar Garg, Robin Callister, Philip Morgan
2011 Sukkar MB, Wood LG, Tooze MK, Simpson JL, McDonald VM, Gibson PG, Wark PA, 'Deficiency of srage in asthma and COPD is selectively associated with neutrophilic airway inflammation', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
Co-authors Peter Wark, Peter Gibson, Jodie Simpson, Vanessa Mcdonald
2011 Wood LG, Scott HA, Gibson PG, 'Systemic inflammation is increased in neutrophilic asthma', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
Co-authors Hayley Scott, Peter Gibson
2011 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Success in a weight loss trial is greatest in subjects with more severe asthma', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
Co-authors Philip Morgan, Peter Gibson, Hayley Scott, Manohar Garg, Robin Callister
2011 McDonald VM, Higgins IJ, Wood LG, Gibson PG, 'Multidimensional assessment and individualized management (MDAIM) of obstructive airway diseases (OAD) in older adults - A pilot clinical trial', Respirology, Perth, WA (2011) [E3]
Co-authors Isabel Higgins, Peter Gibson, Vanessa Mcdonald
2011 Sukkar M, Wood LG, Tooze MK, Simpson JL, McDonald VM, Gibson PG, Wark PA, 'Soluble RAGE is deficient in neutrophilic asthma and COPD', Respirology, Perth, WA (2011) [E3]
DOI 10.1183/09031936.00022011
Citations Scopus - 46Web of Science - 40
Co-authors Vanessa Mcdonald, Jodie Simpson, Peter Gibson, Peter Wark
2011 Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Analysis of systemic gene expression according to inflammatory phenotype of asthma', Respirology, Perth, WA (2011) [E3]
Co-authors Jodie Simpson, Rodney Scott, Peter Gibson, Katherine Baines
2011 Berthon B, MacDonald-Wicks LK, Gibson PG, Wood LG, 'Diet quality is poor in severe asthmatics compared to healthy controls', Respirology, Perth, WA (2011) [E3]
Co-authors Lesley Wicks, Peter Gibson
2011 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Success in a weight loss trial is related to asthma severity', Respirology, Perth, WA (2011) [E3]
Co-authors Philip Morgan, Robin Callister, Manohar Garg, Hayley Scott, Peter Gibson
2011 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Body fat reduction improves clinical asthma outcomes in overweight and obese asthma', Respirology, Perth, WA (2011) [E3]
Co-authors Philip Morgan, Robin Callister, Manohar Garg, Hayley Scott, Peter Gibson
2011 Wood LG, Scott HA, Gibson PG, 'The neutrophilic inflammatory phenotype is associated increased systemic inflammation in asthma', Respirology, Perth, WA (2011) [E3]
Co-authors Hayley Scott, Peter Gibson
2011 Zhong H, Tooze MK, Wood LG, Simpson JL, Wark PA, 'Effect of cigarette smoke extract on neutrophils isolated from human peripheral blood', Respirology, Perth, WA (2011) [E3]
Co-authors Peter Wark, Jodie Simpson
2011 Fu J, Baines KJ, Wood LG, Scott HA, Gibson PG, 'Low-grade systemic inflammation is associated with airway neutrophilia in asthma', Respirology, Shanghai (2011) [E3]
Co-authors Katherine Baines, Hayley Scott, Peter Gibson
2011 Fu J, Baines KJ, Gibson PG, Scott HA, Wood LG, 'Systemic inflammation mediates airway neutrophilia via the regulation of IL-8 receptor mRNA expression', Respirology, Shanghai (2011) [E3]
Co-authors Peter Gibson, Hayley Scott, Katherine Baines
2011 Wood LG, Garg ML, Gibson PG, 'Dietary fat increases airway inflammation and attenuates bronchodilator response in asthma', XI Asian Congress of Nutrition 2011, Singapore (2011) [E3]
Co-authors Peter Gibson, Manohar Garg
2010 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Fatty acids and obesity differentially affect airway inflammation in males and females with asthma', American Journal of Respiratory and Critical Care Medicine, New Orleans (2010) [E3]
Co-authors Manohar Garg, Peter Gibson, Hayley Scott
2010 Wood LG, Garg ML, Wood A, Gibson PG, 'A high fat challenge enhances innate immune responses in asthmatic airways', American Journal of Respiratory and Critical Care Medicine, New Orleans (2010) [E3]
Co-authors Manohar Garg, Peter Gibson
2010 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Caloric restriction and exercise improve clinical asthma outcomes in overweight and obese asthma', Obesity Research & Clinical Practice, Sydney, NSW (2010) [E3]
Co-authors Peter Gibson, Hayley Scott, Manohar Garg, Robin Callister, Philip Morgan
2010 Jensen ME, Gibson PG, Collins CE, Hilton JM, Wood LG, 'Body composition may be associated with systemic and airway inflammation in children with asthma', Obesity Research and Clinical Practice, Sydney, NSW (2010) [E3]
Co-authors Peter Gibson, Clare Collins
2010 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Caloric consumption and exercise improve clinical asthma outcomes in overweight and obese asthma', Obesity Research and Clinical Practice, Sydney, NSW (2010) [E3]
Co-authors Robin Callister, Manohar Garg, Hayley Scott, Peter Gibson, Philip Morgan
2010 Smart JM, Wark PA, McDonald VM, Wood LG, 'Body composition in ex-smokers with and without airflow obstruction', Obesity Research and Clinical Practice, Sydney, NSW (2010) [E3]
Co-authors Vanessa Mcdonald, Peter Wark
2010 Irwin J, Verrills NM, He XY, Powell H, Wood LG, Gibson PG, 'Proteomic biomarkers as novel clinical diagnostics for airway disease', Abstract Book. Human Proteome World Congress Sydney 2010, Sydney, NSW (2010) [E3]
Co-authors Nikki Verrills, Peter Gibson
2010 Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Molecular phenotypes of asthma defined by gene expression profiling', American Journal of Respiratory and Critical Care Medicine, New Orleans, LO (2010) [E3]
Co-authors Rodney Scott, Peter Gibson, Jodie Simpson, Katherine Baines
2010 Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Analysis of systemic gene expression according to inflammatory phenotype of asthma', Biomarker Discovery Conference, Shoal Bay, NSW (2010) [E3]
Co-authors Rodney Scott, Jodie Simpson, Peter Gibson, Katherine Baines
2010 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Clinical asthma outcomes are improved by caloric restriction and exercise in overweight and obese asthma', Proceedings of the Nutrition Society of Australia, Perth (2010) [E3]
Co-authors Peter Gibson, Hayley Scott, Manohar Garg, Robin Callister, Philip Morgan
2010 Smart JM, Wark PA, McDonald VM, Wood LG, 'Low levels of body fat and obstructive airway disease in ex-smokers', Proceedings of the Nutrition Society of Australia, Perth (2010) [E3]
Co-authors Peter Wark, Vanessa Mcdonald
2010 McDonald VM, Higgins IJ, Wood LG, Gibson PG, 'Multidimensional assessment and individualised management of obstructive airway diseases (OAD) in older adults', European Respiratory Society Annual Congress 2010. Abstracts, Barcelona, Spain (2010) [E3]
Co-authors Vanessa Mcdonald, Isabel Higgins, Peter Gibson
2010 Wood LG, 'Nutritional approaches to managing inflammation in asthma', Proceedings of the Nutrition Society of Australia, Perth, WA (2010) [E3]
2010 McLernon PC, Murphy VE, Wood LG, Dekker GA, Hodyl NA, Clifton VL, 'Maternal plasma circulating levels of omega (n)3 long chain polyunsaturated fatty acids, eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA) are associated with fetal growth measures', The Endocrine Society of Australia Annual Scientific Meeting Proceedings and Abstract Book, Sydney (2010) [E3]
Co-authors Vicki Clifton, Vanessa Murphy
2010 McLernon PC, Wood LG, Murphy VE, Dekker GA, Clifton VL, 'Maternal circulating levels of omega (N)3 long chain polyunsaturated fatty acids, eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaunoic acid (DHA) during early pregnancy are associated with detal growth meaures in later pregnancy', Placenta, Kumamoto, Japan (2010) [E3]
Co-authors Vicki Clifton, Vanessa Murphy
2010 Baines KJ, Simpson JL, Scott RJ, Wood LG, Gibson PG, 'Molecular profiling of asthma defined by gene expression', Respirology, Brisbane, QLD (2010) [E3]
Co-authors Jodie Simpson, Katherine Baines, Peter Gibson
2010 Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Molecular phenotypes of asthma defined by gene expression profiling', Respirology, Brisbane, QLD (2010) [E3]
Co-authors Peter Gibson, Rodney Scott, Katherine Baines, Jodie Simpson
2010 Jensen ME, Collins CE, Gibson PG, Hilton JM, Wood LG, 'Obesity is associated with increased airway inflammation in children with asthma', Respirology, Brisbane, QLD (2010) [E3]
Co-authors Peter Gibson, Clare Collins
2010 Smart JM, Wark PA, McDonald VM, Wood LG, 'CRP, body composition and lung function in ex-smokers', Respirology, Brisbane, QLD (2010) [E3]
Co-authors Vanessa Mcdonald, Peter Wark
2010 Wood LG, Garg ML, Wood A, Gibson PG, 'Dietary fat enhances airway inflammation in asthma', Respirology, Brisbane, QLD (2010) [E3]
Co-authors Manohar Garg, Peter Gibson
2010 Jensen ME, Collins CE, Gibson PG, Hilton JM, Wood LG, 'Obesity affects airway inflammation in asthmatic children', Nutrition & Dietetics, Melbourne (2010) [E3]
Co-authors Peter Gibson, Clare Collins
2009 Baines KJ, Simpson JL, Scott R, Wood LG, Gibson PG, 'Genome wide gene expression of induced sputum in non-eosinophilic asthma', AMATA 2009, Katoomba, NSW (2009) [E3]
Co-authors Peter Gibson, Jodie Simpson, Rodney Scott, Katherine Baines
2009 Addnan FH, Wood LG, Garg ML, Wark PA, 'Resveratrol prevents hydrogen peroxide induced cytotoxicity', Proceedings of the Nutrition Society of Australia, Newcastle, NSW (2009) [E3]
Co-authors Peter Wark, Manohar Garg
2009 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Plasma fatty acid profiles are different in obese versus non-obese asthma', Proceedings of the Nutrition Society of Australia, Newcastle, NSW (2009) [E3]
Co-authors Manohar Garg, Peter Gibson, Hayley Scott
2009 Wood LG, Gibson PG, 'Antioxidant defences are impaired in asthmatics with airway hyperresponsiveness, poor control and severe disease pattern', Proceedings of the Nutrition Society of Australia, Newcastle, NSW (2009) [E3]
Co-authors Peter Gibson
2009 Wood AJ, Gibson PG, Wood LG, 'Effects of a high fat, high energy food challenge on mood, fatigue and gastrointestinal symptoms', Proceedings of the Nutrition Society of Australia, Newcastle, NSW (2009) [E3]
Co-authors Peter Gibson
2009 McDonald VM, Wood LG, Smart JM, Higgins IJ, Gibson PG, 'Sacropenia and sarcopenic obesity in older people with COPD?', Proceedings of the Nutrition Society of Australia, Newcastle, NSW (2009) [E3]
Co-authors Peter Gibson, Isabel Higgins, Vanessa Mcdonald
2009 McDonald VM, Wood LG, Smart J, Higgins I, Gibson PG, 'An Investigation of Sarcopenic Obesity in COPD.', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2009) [E3]
Co-authors Vanessa Mcdonald, Peter Gibson, Isabel Higgins
2009 Scott HA, Gibson PG, Garg ML, Smart J, Wood LG, 'Neutrophilic Airway Inflammation Links Asthma and Obesity', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2009) [E3]
Co-authors Manohar Garg, Peter Gibson, Hayley Scott
2009 McDonald VM, Wood LG, Smart JM, Higgins IJ, Gibson PG, 'Does sarcopenic obesity exist in older people with COPD?', Respirology, Darwin, NT (2009) [E3]
DOI 10.1111/j.1440-1843.2009.01503_1.x
Co-authors Peter Gibson, Isabel Higgins, Vanessa Mcdonald
2009 Baines KJ, Wood LG, Gibson PG, 'Molecular mechanisms of airway neutrophilia following a low antioxidant diet', Respirology, Darwin, NT (2009) [E3]
DOI 10.1111/j.1440-1843.2009.01503_1.x
Co-authors Katherine Baines, Peter Gibson
2009 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Asthma and obesity are linked via neutrophilic airway inflammation', Respirology, Darwin, NT (2009) [E3]
DOI 10.1111/j.1440-1843.2009.01503_1.x
Co-authors Hayley Scott, Manohar Garg, Peter Gibson
2009 Wood LG, Garg ML, Smith AJ, Smart JM, Gibson PG, 'A high fat, high energy food challenge induces an exaggerated inflammatory response in asthma', Respirology, Darwin, NT (2009) [E3]
DOI 10.1111/j.1440-1843.2009.01503_1.x
Co-authors Manohar Garg, Peter Gibson
2008 Wood LG, Garg ML, Smith AJ, Smart JM, Gibson PG, 'A high fat challenge activates the innate immune response in asthma', Asia Pacific Journal of Clinical Nutrition, Adelaide, SA (2008) [E3]
Co-authors Peter Gibson, Manohar Garg
2008 Wood LG, Attia JR, McElduff P, McEvoy MA, Flood V, Gibson PG, 'Dietary fat and an activated innate immune response are associated with reduced FEV1', Asia Pacific Journal of Clinical Nutrition, Adelaide, SA (2008) [E3]
Co-authors Peter Gibson, Patrick Mcelduff, John Attia
2008 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Obesity is associated with increased inflammation in asthma', Asia Pacific Journal of Clinical Nutrition, Adelaide, SA (2008) [E3]
Co-authors Peter Gibson, Manohar Garg, Hayley Scott
2008 Jackson B, Powell H, Wood LG, Gibson PG, 'A comparison of two real-time nitric oxide analysers', Asia Pacific Journal of Clinical Nutrition, Adelaide, SA (2008) [E3]
Co-authors Peter Gibson
2008 McLernon PC, Wood LG, Murphy VE, Dekker GA, Clifton VL, 'Maternal circulating antioxidant levels in pregnancies complicated by asthma', 51st Annual Scientific Meeting of the Endocrine Society of Australia and Society of Reproductive Biology: Meeting Proceedings and Abstract Book, Melbourne, VIC (2008) [E3]
Co-authors Vanessa Murphy
2008 Hazelwood L, Wood LG, Hansbro PM, Foster PS, 'High fat diet reduces eosinophilic lung inflammation via nicotinic acetylcholine-dependent signaling', Australasian Society for Immunology 38th Annual Scientific Meeting: Delegate Book, Canberra, ACT (2008) [E3]
Co-authors Paul Foster, Philip Hansbro
2007 Saedi Some Olia A, Garg ML, Wood LG, Wark PA, Gibson PG, 'Lycopene enrichment of cultured epithelial airway cells', Asia Pacific Journal of Clinical Nutrition, Auckland, New Zealand (2007) [E3]
Co-authors Manohar Garg, Peter Wark, Peter Gibson
2007 Saedi Some Olia A, Garg ML, Wood LG, Gibson PG, Wark PA, 'Anti-inflammatory effect of lycopene enrichment on infected cultured airway epithelial cells', Respirology (Abstracts of the 12th Congress of the Asian Pacific Society of Respirology), Gold Coast, QLD (2007) [E3]
Co-authors Peter Wark, Manohar Garg, Peter Gibson
2007 Powell H, Smart J, Wood LG, Gibson PG, 'Validity of the common cold questionnaire V(CCQ) in asthma exacerbations', Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3]
Citations Scopus - 10Web of Science - 7
Co-authors Peter Gibson, Michael Hensley
2007 Wood LG, Garg ML, Powell H, Gibson PG, 'Dietary lycopene reduces neutrophilic airway inflammation in asthma', Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3]
Co-authors Peter Gibson, Manohar Garg
2007 Timmins NL, Wood LG, Simpson JL, Gibson PG, 'Optimising exhaled breath condensate collection', Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3]
Co-authors Jodie Simpson, Peter Gibson
2006 Wood LG, Garg ML, Gibson PG, 'Asthma control deteriorates on a low antioxidant diet', European Respiratory Journal Supplement, Munich, Germany (2006) [E3]
Co-authors Peter Gibson, Manohar Garg
2006 Wood LG, Garg ML, Powell HG, Gibson PG, 'Dietary lycopene and asthma control: A randomized control trial', Asia Pacific Journal of Clinical Nutrition, Sydney (2006) [E3]
Co-authors Manohar Garg, Peter Gibson
2006 Micallef MA, Garg ML, Wood LG, Murphy VE, Clifton VL, 'Dietry intake of long chain n-3 polyunsaturated fatty acids in adults with asthma', Asia Pacific Journal of Clinical Nutrition, Sydney, New South Wales (2006) [E3]
Co-authors Manohar Garg, Vanessa Murphy, Vicki Clifton
2006 Saedisomeolia A, Garg ML, Wood LG, Gibson PG, 'Lycopene supplementation does not influence cytokine profile in asthma patients', Asia Pacific Journal of Clinical Nutrition, Sydney, New South Wales (2006) [E3]
Co-authors Peter Gibson, Manohar Garg
2006 Wark PA, Wood LG, Grissell TV, Davies B, Shafren DR, Powell HG, et al., 'Acute virus-induced asthma is characterised by increased expression of toll-like receptors (TLR)-2', Respirology, Canberra (2006) [E3]
Co-authors Michael Hensley, Peter Gibson, Peter Wark
2006 Wood LG, Garg ML, Gibson PG, 'A low antioxidant diet worsens asthma control', Respirology, Canberra (2006) [E3]
Co-authors Peter Gibson, Manohar Garg
2006 Wood LG, Garg ML, Powell H, Gibson PG, 'Modifying Dietary Antioxidant Consumption Affects Clinical Status and Noneosinophilic Airway Inflammation in Asthma', Respirology, Japan (2006) [E3]
Co-authors Peter Gibson, Manohar Garg
2005 Wood LG, Garg ML, Blake RJ, Simpson JL, Gibson PG, 'Systemic and airway levels of glutathione and alpha-tocopherol in asthma', Asia Pacific Journal of Clinical Nutrition, Australia (2005) [E3]
Co-authors Jodie Simpson, Manohar Garg, Peter Gibson
2000 Fitzgerald D, Wood LG, Gibson PG, Cooper D, Garg ML, 'Elevated plasma levels of 8-iso-PGF2a in asthma', American Journal of Respiratory and Critical Care Medicine ISSN 1073-449X, Seattle, USA (2000) [E3]
Co-authors Peter Gibson, Manohar Garg
2000 Wood LG, Garg ML, 'Cystic Fibrosis - the Human Model of Oxidative Stress', Proceedings of the 8th World Congress of Clinical Nutrition, Phitsanulok (2000) [E3]
Co-authors Manohar Garg
1999 Wood LG, Fitzgerald D, Gibson PG, Cooper D, Collins CE, Garg ML, 'Isoprostanes as a Novel Marker of Oxidative Stress in Cystic Fibrosis', 3rd Australian Cystic Fibrosis Conference, Sydney, Australia (1999) [E3]
Co-authors Peter Gibson, Manohar Garg, Clare Collins
1999 Wood LG, Fitzgerald D, Gibson PG, Cooper D, Collins CE, Garg ML, '8-ISO-PGF2a and Oxidative Stress in Cystic Fibrosis', Weighing the Evidence Programme and Proceedings, Auckland, New Zealand (1999) [E3]
Co-authors Peter Gibson, Clare Collins, Manohar Garg
1998 Wood LG, Fitzgerald D, Cooper D, Gibson PG, Garg ML, 'Antioxidant defenses in cystic fibrosis patients', Proceedings of the Nutrition Society of Australia, Adelaide, South Australia (1998) [E3]
Co-authors Manohar Garg, Peter Gibson
Show 116 more conferences

Patent (1 outputs)

Year Citation Altmetrics Link
2006 Gibson PG, Wood LG, Garg ML, Method for evaluating status of asthma control (2006) [I3]
Co-authors Peter Gibson, Manohar Garg

Creative Work (1 outputs)

Year Citation Altmetrics Link
2011 McDonald VM, Wark PA, Gibson PG, Alison J, Spencer L, Wood LG, Roberts M, Living with COPD: Chronic Obstructive Pulmonary Disease, The Australian Lung Foundation, Newcastle (2011) [J2]
Co-authors Peter Gibson, Peter Wark, Vanessa Mcdonald
Edit

Grants and Funding

Summary

Number of grants 55
Total funding $3,254,207

Click on a grant title below to expand the full details for that specific grant.


20153 grants / $825,726

Mechanisms of impaired bronchodilator response associated with fatty acid intake in obese asthma$680,504

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Associate Professor Lisa Wood, Dr Brian Oliver, Associate Professor Paul Young
Scheme Project Grant
Role Lead
Funding Start 2015
Funding Finish 2015
GNo G1400042
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Improving diet quality to reduce risk of asthma attacks in children$120,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Lisa Wood, Professor Joerg Mattes, Conjoint Professor Peter Wark, Doctor Katie Baines, Miss Megan Jensen
Scheme Project Grant
Role Lead
Funding Start 2015
Funding Finish 2015
GNo G1500957
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Dietary fibre as a modulator of airway inflammation in asthma$25,222

Funding body: John Hunter Hospital Charitable Trust Fund

Funding body John Hunter Hospital Charitable Trust Fund
Project Team Ms BRONWYN Berthon, Associate Professor Lisa Wood, Doctor David Arnold
Scheme Research Grant
Role Investigator
Funding Start 2015
Funding Finish 2015
GNo G1500693
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

20148 grants / $161,010

Exercise Training as a Potential Treatment for Eosinophilic Airway Inflammation in Asthma$26,648

Funding body: John Hunter Hospital Charitable Trust Fund

Funding body John Hunter Hospital Charitable Trust Fund
Project Team Doctor Hayley Scott, Associate Professor Lisa Wood, Conjoint Associate Professor Nick Saltos
Scheme Research Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1400219
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

Validation of a Food Frequency Questionnaire to detect changes in diet-related cardiovascular disease risk$25,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Clare Collins, Professor Robin Callister, Doctor Tracy Burrows, Associate Professor Lisa Wood, Ms Tracy Schumacher
Scheme Cardiovascular Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1301346
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Effects of two different diets on inflammatory and oxidative stress biomarker responses to exercise in overweight men and women$25,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Robin Callister, Associate Professor Lisa Wood, Professor Clare Collins
Scheme Project Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1301398
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Miltenyi Biotec GentleMACS Octo Dissociator with Heaters $23,566

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Phil Hansbro, Laureate Professor Paul Foster, Professor Darryl Knight, Professor Dirk Van Helden, Professor Joerg Mattes, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Associate Professor Liz Milward, Dr NATHAN Bartlett, Doctor Simon Keely, Doctor Steven Maltby, Doctor Andrew Jarnicki, Doctor Malcolm Starkey, Doctor Adam Collison, Ms Shaan Gellatly
Scheme Equipment Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1500861
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Investigating the role of dietary fat in reducing the efficacy of bronchodilator medications in asthma$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Lisa Wood
Scheme VIVA Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1301345
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Mechanisms of impaired bronchodilator response associated with fatty acid intake in obese asthma $20,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Lisa Wood
Scheme Near Miss Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1301408
Type Of Funding Internal
Category INTE
UON Y

Saturated fats may promote cardiovascular health$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Manohar Garg, Associate Professor Lisa Wood
Scheme Project Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1401400
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Thoracic Society of Australia and New Zealand, Adelaide, South Australia, 5-9 April 2014$796

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Associate Professor Lisa Wood
Scheme Travel Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1400509
Type Of Funding Internal
Category INTE
UON Y

20137 grants / $594,506

RCT of fruit and vegetable supplement to reduce inflammation in obese, elderly adults$250,000

RCT of fruit and vegetable supplement to reduce inflammation in obese, elderly adults

Funding body: Newcastle Innovation

Funding body Newcastle Innovation
Project Team
Scheme project grant
Role Lead
Funding Start 2013
Funding Finish 2015
GNo
Type Of Funding External
Category EXTE
UON Y

Clinical evaluation of a novel olive leaf formulation for heart health$165,000

Funding body: Newcastle Innovation

Funding body Newcastle Innovation
Project Team Professor Peter Howe, Professor Manohar Garg, Doctor Rachel Wong, Associate Professor Lisa Wood
Scheme Administered Research
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1401244
Type Of Funding Internal
Category INTE
UON Y

Immunometabolism in Obese Asthmatics$73,959

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Conjoint Professor Peter Gibson, Associate Professor Lisa Wood
Scheme Project Grant
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1300196
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Lipemic Index of Pork$50,000

Funding body: CRC for High Integrity Australian Pork

Funding body CRC for High Integrity Australian Pork
Project Team Professor Manohar Garg, Associate Professor Lisa Wood, Professor Peter Howe
Scheme Innovative Research
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1201031
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Dietary antioxidant intervention for reversal of airway inflammation and respiratory illness in athletes$29,737

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Lisa Wood, Emeritus Professor Maree Gleeson, Professor Robin Callister
Scheme Project Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1300899
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Nutritional Determinants of Success in COPD Rehabilitation$23,810

Funding body: John Hunter Hospital Charitable Trust Fund

Funding body John Hunter Hospital Charitable Trust Fund
Project Team Associate Professor Lisa Wood, Doctor David Arnold
Scheme Research Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1301099
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

American Thoracic Society Conference, USA 17-22 May 2013$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Associate Professor Lisa Wood
Scheme Travel Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1300788
Type Of Funding Internal
Category INTE
UON Y

20128 grants / $289,573

Fatty acids and bronchodilator responses in asthma$70,000

Funding body: Thoracic Society of Australia and New Zealand

Funding body Thoracic Society of Australia and New Zealand
Project Team Associate Professor Lisa Wood, Dr Brian Oliver, Associate Professor Paul Young, Associate Professor Daniela Traini
Scheme The Novartis TSANZ Lung Health Research Grant In Aid Award
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1201132
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Dietary fructose restriction improves plasma lipids, satiety hormones and inflammation in obesity$45,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Manohar Garg, Associate Professor Lisa Wood
Scheme Project Grant
Role Investigator
Funding Start 2012
Funding Finish 2013
GNo G1101123
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

A laboratory-based model to identify the risk of respiratory illness in athletes$41,820

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Emeritus Professor Maree Gleeson, Associate Professor Lisa Wood, Professor Robin Callister
Scheme Project Grant
Role Investigator
Funding Start 2012
Funding Finish 2012
GNo G1200759
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Diagnosing and managing respiratory illness in athletes$37,500

Funding body: Australian Sports Commission, Incorporating Australian Institute of Sport

Funding body Australian Sports Commission, Incorporating Australian Institute of Sport
Project Team Emeritus Professor Maree Gleeson, Professor David Pyne, Associate Professor Lisa Wood, Professor Robin Callister
Scheme PhD Scholarship Funding
Role Investigator
Funding Start 2012
Funding Finish 2012
GNo G1101194
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Body plethysmograph respiratory function system$33,076

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Gibson, Conjoint Professor Peter Wark, Associate Professor Lisa Wood, Associate Professor Jodie Simpson, Doctor Katie Baines, Doctor Vanessa Murphy, Doctor Jeffrey Pretto, Emeritus Professor Michael Hensley, Ms Jenny Mackney
Scheme Equipment Grant
Role Investigator
Funding Start 2012
Funding Finish 2012
GNo G1100973
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Fatty acids, Carbohydrates and Bronchodilator Responses in Asthma$24,692

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Lisa Wood, Conjoint Professor Peter Gibson
Scheme Project Grant
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1200618
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

HMRI Grant in Sports Medicine$22,496

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Emeritus Professor Maree Gleeson, Associate Professor Lisa Wood, Professor Robin Callister
Scheme Research Grant
Role Investigator
Funding Start 2012
Funding Finish 2012
GNo G1200065
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Follow-Up of a Weight Loss Intervention in COPD$14,989

Funding body: John Hunter Hospital Charitable Trust Fund

Funding body John Hunter Hospital Charitable Trust Fund
Project Team Associate Professor Lisa Wood, Doctor Hayley Scott, Emeritus Professor Michael Hensley
Scheme Research Grant
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1200763
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

20116 grants / $122,562

MAID: Microarray analysis following anti inflammatory interventions in COPD$47,732

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Associate Professor Lisa Wood, Conjoint Professor Peter Gibson
Scheme Centres of Research Excellence (CRE) - Centres of Clinical Research Excellence
Role Lead
Funding Start 2011
Funding Finish 2011
GNo G1100019
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

To determine if asthmatics and children at risk of asthma that develop acute exacerbations have defective antiviral innate immune responses$28,000

Funding body: John Hunter Hospital Charitable Trust Fund

Funding body John Hunter Hospital Charitable Trust Fund
Project Team Conjoint Professor Peter Wark, Doctor Larry Roddick, Associate Professor Lisa Wood
Scheme Research Grant
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1100177
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

Obesity Risk in Childhood Asthma (ORCA) - 1 yr RhD Support$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Lisa Wood, Miss Megan Jensen
Scheme Research Higher Degree Support Grant
Role Lead
Funding Start 2011
Funding Finish 2011
GNo G1001008
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Antioxidant therapies for suppressing infection-induced asthma in children$15,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Jay Horvat, Associate Professor Lisa Wood, Professor Phil Hansbro
Scheme Youth Research Project Grant
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1001002
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Lung Function (Spirometry) testing and sputum induction equipment - establishing 3 new clinical workstations. Medgraphics CPFS/d USB spirometer with breezesuite software (x3). Laptop computer (x3). Ul$10,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Doctor Katie Baines, Conjoint Professor Peter Wark, Doctor Vanessa Murphy
Scheme Equipment Grant
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1100038
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

XI Asian Congress of Nutrition 2011, Singapore, 13 - 16 July 2011$1,830

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Associate Professor Lisa Wood
Scheme Travel Grant
Role Lead
Funding Start 2011
Funding Finish 2011
GNo G1100729
Type Of Funding Internal
Category INTE
UON Y

20104 grants / $70,000

Real time PCR machine (Mastercycler ep realplex2 from Epprndorf) $34,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Associate Professor Jodie Simpson, Conjoint Professor Peter Gibson, Conjoint Professor Peter Wark, Associate Professor Lisa Wood, Doctor Vanessa Murphy, Doctor Robert Scott, Doctor Katie Baines
Scheme Equipment Grant
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo G1000056
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Identifying novel biomarkers of oxidative stress in chronic obstructive pulmonary disease$25,000

Funding body: Hunter Children`s Research Foundation

Funding body Hunter Children`s Research Foundation
Project Team Conjoint Professor Peter Wark, Associate Professor Lisa Wood
Scheme Research Grant
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo G0900145
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

HMRI PULSE Early Career Award$9,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Lisa Wood
Scheme PULSE Early Career Researcher of the Year Award
Role Lead
Funding Start 2010
Funding Finish 2010
GNo G1000469
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

American Thoracic Society International Conference, New Orleans, Louisiana, USA, 14 - 19th May 2010$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Associate Professor Lisa Wood
Scheme Travel Grant
Role Lead
Funding Start 2010
Funding Finish 2010
GNo G1000139
Type Of Funding Internal
Category INTE
UON Y

20092 grants / $77,500

A study of Obesity and inflammation in Children with Asthma$50,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Lisa Wood, Professor Clare Collins
Scheme Research Grant
Role Lead
Funding Start 2009
Funding Finish 2009
GNo G0190513
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

394591 ELx405UV select plate washer and workstation integration kit$27,500

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Gibson, Doctor Xiao Yan He, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Conjoint Professor Peter Wark
Scheme Equipment Grant
Role Investigator
Funding Start 2009
Funding Finish 2009
GNo G0189853
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20086 grants / $759,345

High fat diets and airway inflammation in asthma$490,803

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Associate Professor Lisa Wood
Scheme Project Grant
Role Lead
Funding Start 2008
Funding Finish 2008
GNo G0187594
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Exploring the link between obesity and asthma$75,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Lisa Wood, Conjoint Professor Peter Gibson, Professor Manohar Garg
Scheme Post Graduate Support Grant
Role Lead
Funding Start 2008
Funding Finish 2008
GNo G0188479
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Obesity and intermittent hypoxia as drivers of imflammation and insulin resistance in obstructive sleep apnoea$66,771

Funding body: CCRE in Respiratory and Sleep Medicine

Funding body CCRE in Respiratory and Sleep Medicine
Project Team Associate Professor Lisa Wood, Emeritus Professor Michael Hensley
Scheme Postgraduate Research Scholarship
Role Lead
Funding Start 2008
Funding Finish 2008
GNo G0188633
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Exploring the link between asthma and obesity$66,771

Funding body: CCRE in Respiratory and Sleep Medicine

Funding body CCRE in Respiratory and Sleep Medicine
Project Team Associate Professor Lisa Wood, Conjoint Professor Peter Gibson, Professor Manohar Garg, Ms Hayley Scott
Scheme Postgraduate Research Scholarship
Role Lead
Funding Start 2008
Funding Finish 2008
GNo G0188635
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Becton Dickinson high throughout sampler for the FACSCanto II cytometry system$35,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Doctor Vanessa Murphy, Professor Phil Hansbro
Scheme Equipment Grant
Role Investigator
Funding Start 2008
Funding Finish 2008
GNo G0188547
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Trans Fatty acids and airway inflammation$25,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Lisa Wood, Conjoint Professor Peter Gibson, Professor Manohar Garg
Scheme Project Grant
Role Lead
Funding Start 2008
Funding Finish 2008
GNo G0188472
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20077 grants / $130,178

Nitric Oxide Monitoring System (NIOX)$45,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Gibson, Conjoint Associate Professor Vicki Clifton, Conjoint Professor Warwick Giles, Emeritus Professor Michael Hensley, Doctor Vanessa Murphy, Conjoint Professor Peter Wark, Associate Professor Vanessa McDonald, Associate Professor Jodie Simpson, Conjoint Associate Professor Bruce Whitehead, Laureate Professor Paul Foster, Professor Phil Hansbro, Associate Professor Lisa Wood
Scheme Equipment Grant
Role Investigator
Funding Start 2007
Funding Finish 2007
GNo G0188193
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Healthy Airways and Obstructive Lung Disease (HAROLD)$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Conjoint Professor Wayne Smith, Associate Professor Lisa Wood, Professor John Attia, Associate Professor Regina Berretta, Professor Pablo Moscato
Scheme Project Grant
Role Investigator
Funding Start 2007
Funding Finish 2007
GNo G0187246
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Hewlett Packard 7890 series gas chromatograph with accessories$20,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Associate Professor Lisa Wood, Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Doctor Vanessa Murphy, Laureate Professor Paul Foster, Professor Phil Hansbro, Conjoint Associate Professor Vicki Clifton, Professor Clare Collins, Conjoint Professor Wayne Smith, Professor John Attia
Scheme Equipment Grant
Role Lead
Funding Start 2007
Funding Finish 2007
GNo G0188191
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Class II biohazard containment hood and carbon dioxide cell culture incubator$20,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Doctor Vanessa Murphy, Associate Professor Lisa Wood, Laureate Professor Paul Foster, Professor Phil Hansbro
Scheme Equipment Grant
Role Investigator
Funding Start 2007
Funding Finish 2007
GNo G0188192
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

High energy diets and airway inflammation$14,500

Funding body: John Hunter Hospital Charitable Trust Fund

Funding body John Hunter Hospital Charitable Trust Fund
Project Team
Scheme Unknown
Role Lead
Funding Start 2007
Funding Finish 2007
GNo
Type Of Funding Not Known
Category UNKN
UON Y

Can we get kids participating in an obesity intervention to eat more vegetables, fruit and less saturated fat long-term?$7,678

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Clare Collins, Associate Professor Lisa Wood
Scheme Pilot Grant
Role Investigator
Funding Start 2007
Funding Finish 2007
GNo G0187883
Type Of Funding Internal
Category INTE
UON Y

Pulse Education Prize$3,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Lisa Wood
Scheme PULSE Education Prize
Role Lead
Funding Start 2007
Funding Finish 2007
GNo G0187386
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20051 grants / $25,000

HPLC with electrochemical detector$25,000

Funding body: Ramaciotti Foundations

Funding body Ramaciotti Foundations
Project Team Conjoint Professor Peter Gibson, Associate Professor Lisa Wood
Scheme Major Equipment Award
Role Investigator
Funding Start 2005
Funding Finish 2005
GNo G0185635
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20031 grants / $15,000

Carotenoids and flavonoids in asthma$15,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Conjoint Professor Peter Gibson, Professor Manohar Garg, Associate Professor Lisa Wood
Scheme Project Grant
Role Investigator
Funding Start 2003
Funding Finish 2003
GNo G0182435
Type Of Funding Internal
Category INTE
UON Y

20021 grants / $121,525

A nutritional approach to reducing oxidative stress and improving disease control in asthma.$121,525

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Associate Professor Lisa Wood
Scheme Training (Postdoctoral) Fellowships - Australian Part-time Research Fellowship
Role Lead
Funding Start 2002
Funding Finish 2002
GNo G0181208
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

19981 grants / $62,282

Oxidative stress and antioxidants in cystic fybrosis$62,282

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Associate Professor Lisa Wood
Scheme Dora Lush Postgraduate Research Scholarship
Role Lead
Funding Start 1998
Funding Finish 1998
GNo G0181960
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y
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Research Supervision

Number of supervisions

Completed8
Current11

Total current UON EFTSL

PhD3.85

Current Supervision

Commenced Level of Study Research Title / Program / Supervisor Type
2015 PhD Fatty Acids and Bronchodilator Responses
Microbiology, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2015 PhD Identification of Abnormalities in Innate Immunity in Asthma
General Medicine, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2015 PhD Dietary Fibre As A Modulator of Inflammation In Asthma
Medical Science, Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2015 PhD Fruit and Vegetable Extract for the Reduction of Obesity-Induced Inflammation
Medical Science, Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2014 PhD The Effect of Hormonal Markers on the Anthropometry and Physical Performance of Professional Rugby League Players
Human Movement, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2012 PhD Sex Differences in Obesity and Responses to Obesity Treatment
Human Biology, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2012 PhD Fatty Acids and the Innate Immune Response
Medical Science, Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2012 PhD Dietary Fats and Biomarkers of Human Health: Excess Saturated Fat or Lack of Omega 3 Fatty Acids
Pharmacy, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2012 PhD Immunometabolism in Obese Asthma
General Medicine, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2011 PhD Dietary fructose and cardio-metabolic health
Pharmacy, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2008 PhD A characterisation of maternal circulating fatty acids and antioxidants and their relationship to fetal growth in pregnancies complicated by asthma
Obstetrics & Gynaecology, University of Adelaide
Co-Supervisor

Past Supervision

Year Level of Study Research Title / Program / Supervisor Type
2015 PhD Oxidative Stress Impairs Mitochondrial Function in Healthy and Asthmatic Primary Bronchial Epithelial Cells
General Medicine, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2014 PhD Investigating the Link Between Corticosteroids and Diet in Adults with Asthma
Medical Science, Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2014 PhD Role of Antioxidants in Rhinovirus-Infected Airway Epithelial Cells
Medical Science, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2013 PhD Paediatric Obesity, Inflammation and Asthma
General Medicine, Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2013 Masters An Investigation of Body Composition in People With and Without Chronic Obstructive Pulmonary Disease (COPD)
General Medicine, Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2012 PhD Exploring the Link Between Obesity and Asthma
General Medicine, Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2009 PhD Nutritional Modulation of Lung Inflammation
Microbiology, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2008 PhD Role of Lycopene and Long Chain n-3 Polyunsaturated Fatty Acid Supplements in Airway Inflammation
Human Biology, Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
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News

New study to examine fibre effect on asthma

June 15, 2015

Respiratory researchers from the University of Newcastle and HMRI are looking into whether a high-fibre diet can reduce airway inflammation in people with asthma.

Associate Professor Lisa Wood

Fruit-and-veg capsule set to combat obesity impacts

March 24, 2014

Hunter Medical Research Institute researchers are examining whether a simple fruit-and-vegetable supplement, taken in capsule form, can reduce inflammation produced by fat cells and thereby lower the risk of heart disease, diabetes, asthma and cancers in overweight people.

Associate Professor Lisa Wood

Position

Associate Professor
Centre for Asthma and Respiratory Diseases
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine

Focus area

Pharmacy and Experimental Pharmacology

Contact Details

Email lisa.wood@newcastle.edu.au
Phone 02 40420147
Fax 02 40420046

Office

Room Level 2, West Wing
Building Hunter Medical Research Institute
Location HMRI, Kookaburra Circuit, New Lambton

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