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Professor Peter Howe

Research Professor

School of Biomedical Sciences and Pharmacy (Nutrition and Dietetics)

Career Summary

Biography

Peter is Professor of Nutrition Research in the School of Biomedical Sciences and Pharmacy and Director of the Clinical Nutrition Research Centre, a new cross institutional research collaboration based at the University of Newcastle. He is also an Adjunct Professor in Nutritional Physiology at the University of South Australia and Adjunct Professor in Physiology at the University of Adelaide. With an extensive track record of multidisciplinary preclinical and clinical research in nutrition, cardiovascular physiology, neuroscience and more recently mental health, he is recognised as an authority on cardiovascular and metabolic health benefits of omega-3 fatty acids and other bioactive nutrients. Peter has published over 200 papers with 4800 citations (H-index = 35). His goal is the scientific substantiation and promotion of health benefits of functional foods and nutraceuticals through collaborative partnerships with industry. He is joint Editor-in-Chief of the online journal Nutrients and a Fellow of the Nutrition Society of Australia.

  Research Expertise
Peter has a long-standing track record of preclinical and clinical research in cardiovascular/autonomic physiology and in nutrition addressing the pathogenesis, prevention and management of cardiovascular and metabolic disorders. His current research focuses on the role of diet and lifestyle in health optimisation: the impact of nutritional and exercise interventions on biomarkers of cardiovascular, metabolic and mental health; the elucidation of underlying mechanisms of action; the development of an integrated approach to risk factor management (including nutrients as adjunct therapy). Peter's research also encompasses food sources, bioavailability and intake recommendations for nutrients, esp. omega-3 fatty acids.

Teaching Expertise
Peter has extensive experience in supervising honours and PhD students and in mentoring postdoctoral and early career researchers, having supervised 18 higher degree research and 26 honours research students. Peter has also given invited lectures in both Human Nutrition and Nutrition & Dietetics courses at the University of South Australia, where he conducted Human Research Ethics training workshops. Peter also has experience both lecturing and coordinating undergraduate students from his work at the University of Wollongong, University of Adelaide and Flinders University.

Administrative Expertise
Peter was the inaugural Director of the Smart Foods Centre at the University of Wollongong (1999) and founded and directed the Nutritional Physiology Research Centre at the University of South Australia (2003-2009). He was also Director and Chair of Executive Committee for the Australian Technology Network Centre for Metabolic Fitness from 2005 – 07, a national collaboration researching diet and lifestyle approaches to optimise physical and mental health. Peter has had significant experience on several Human Research Ethics and Experimental Animal Research Ethics committees and is currently Human Research Ethics Advisor at the University of South Australia. He has also held a number of key roles in both the CSIRO and University based research administration. Peter is a regular assessor of grant applications for the National Health and Medical Research Council and the Australian Research Council.

Collaborations
Peter has held several significant leadership roles in collaborative research concentrations at Australian universities and is currently Director of the Clinical Nutrition Research Centre (CNRC), a collaborative initiative between research concentrations at University of Newcastle, University of South Australia and Swinburne University of Technology. He previously founded the following research collaborations: Smart Foods Centre (an ARC Key Centre of Teaching and Research at the University of Wollongong); Nutritional Physiology Research Centre, University of South Australia; ATN Centre for Metabolic Fitness Peter has also built strategic alliances with both primary producers and food manufacturers to develop healthier foods and he convenes the Annual Industry Forum for Nutrition Research. He has also worked as a consultant with many organisations including Food Standards Australia New Zealand and the Australian Food & Grocery Council.


Qualifications

  • PhD, Monash University
  • Bachelor of Science, University of Sydney
  • Master of Science, University of Oxford - UK

Keywords

  • Bioactive nutrients
  • Cardiorespiratory Physiology
  • Cardiovascular and metabolic health
  • Human Nutrition
  • Mental Health
  • Nutrients and Metabolism
  • Omega-3 Fatty Acids
  • Pathophysiology

Fields of Research

CodeDescriptionPercentage
111103Nutritional Physiology100

Professional Experience

UON Appointment

DatesTitleOrganisation / Department
18/06/2015 - 17/06/2017Research ProfessorUniversity of Newcastle
School of Biomedical Sciences and Pharmacy
Australia

Academic appointment

DatesTitleOrganisation / Department
1/01/2010 - Human Research Ethics Advisor University of South Australia
School of Health Sciences
Australia
1/01/2009 - Editor - NutrientsNutrients
Australia
1/01/2007 - Adjunct ProfessorThe University of Adelaide
School of Medical Sciences
Australia
1/06/2005 - Research ProfessorUniversity of South Australia
Nutritional Physiology
Australia
1/01/2001 - Membership - Nutrition AustraliaNutrition Australia
Australia
1/01/1998 - 31/12/2000Membership - Australasian Clinical Research Network (Management Committee)Australasian Clinical Research Network (Management Committee)
Australia
1/01/1997 - Membership - American Oil Chemists Society (Australasian Chapter)American Oil Chemists Society (Australasian Chapter)
United States
1/01/1995 - Membership - International Society for the Study of Fatty Acids & LipidsInternational Society for the Study of Fatty Acids & Lipids
Australia
1/01/1986 - Membership - International Society of HypertensionInternational Society of Hypertension
Australia
1/01/1984 - Fellow - Nutrition Society of AustraliaNutrition Society of Australia
Australia
1/01/1980 - Membership - High Blood Pressure Research Council of AustraliaHigh Blood Pressure Research Council of Australia
Australia

Invitations

Keynote Speaker

YearTitle / Rationale
2011Nutrients and Circulatory Function
Organisation: Food Industry Forum for Nutrition Research

Participant

YearTitle / Rationale
20145th International Conference on Natural Products for Health and Beauty
Organisation: Phuket, May Description: .
20148th Congress, International Society for Nutrigenetics & Nutrigenomics
Organisation: Gold Coast, May Description: .
2013Omega-3 Symposium & AAOCS Biennial Workshop
Organisation: Newcastle, November Description: .
2012Vasoactive Nutrients & Brain Function
Organisation: DSM Nutritional Products & Frutarom Description: .
2012Vasoactive Nutrients & Brain Function
Organisation: Glaxo Smith Kline Description: .
2012Nutrients and Circulatory Function
Organisation: 3rd Annual Food Industry Forum for Nutrition Research Description: .

Speaker

YearTitle / Rationale
2013Science of Nutrition in Medicine Conference
Organisation: Sydney, May Description: .
2012Vasoactive Nutrients and Brain Function
Organisation: Canadian Nutrition Society Description: Invited Speaker at annual conference.
2012Circulatory dysfunction and chronic inflammation: a common target for nutrient intervention
Organisation: Nutrition Society of Australia Newcastle Group meeting Description: .
2012Student Masterclass
Organisation: Nutrition Society of Australia annual meeting Description: .
2012Resveratrol 2012
Organisation: University of Leicester Description: .
2011Omega Index
Organisation: RCPA AACB Chemical Pathology Course
2011Cardiometabolic/mental health benefits of vasoactive nutrients
Organisation: University of Newcastle
2011Cardiometabolic and mental health benefits of vasoactive nutrients
Organisation: Science of Nutrition in Medicine and Healthcare Conference
2011Cardiovascular, metabolic and mental health benefits of vasoactive nutrients
Organisation: Therapeutic Applications of Functional Foods Description:
2011Nutrition and Health & Shape Up for Life
Organisation: CPDENT: Dental Practice Update Description:
2011Nutraceuticals in Health and Disease
Organisation: 5th International Conference on Mechanisms of Action of Nutraceuticals Description:
2011Erythrocyte omega-3 levels - an alternative basis for intake recommendations
Organisation: Australasian Section of the American Oil Chemists Society Description: Invited speaker at Health and nutrition session.
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (18 outputs)

YearCitationAltmetricsLink
2009Buckley JD, Coates AM, Howe PRC, 'Alpha-cyclodextrin', iber Ingredients: Food Applications and Health Benefits, CRC Press, Boca Raton, Florida, United States of America 9-18 (2009) [B1]
2009Buckley JD, Howe PRC, 'Long-chain omega-3 polyunsaturated fatty acids and obesity', Fatty Acids in Health Promotion and Disease Causation, AOCS Press, Berlin, Germany 767-786 (2009) [B1]
2009Murphy K, Howe PRC, 'Food Sources and Intakes of Omega-3 fatty acids', Fatty Acids in Health Promotion and Disease Causation, AOCS Press, Berlin, Germany 787-818 (2009) [B1]
2009Coates AM, Howe PRC, 'Fatty Acids in nuts', Fatty Acids in Health Promotion and Disease Causation, AOCS Press, Berlin, Germany 253-283 (2009) [B1]
2009Sinn N, Milte C, Howe PRC, 'From ADHD to Alzheimer's: Omega-3 fatty acids and mental health', Fatty Acids in Health Promotion and Disease Causation, AOCS Press, Berlin, Germany 611-641 (2009) [B1]
2006Buckley J, Hill A, Coates A, Howe PRC, 'Simpler diet and exercise solutions for managing obesity', Physical Activity and Obesity, Smith-Gordon, London, United Kingdom (2006) [B1]
2002Liu L-X, Howe PRC, Su C-W, Sun F, Zhang R, 'Comparative analysis of the ITS rDNA sequence and nutrient compositions of an unnamed Ganoderma species in Australia', Ganoderma: Genetics, Chemistry, Pharmacology and Therapeutics, Beijing Medical University Press, Beijing, China 67-74 (2002) [B1]
2002Meyer BJ, Larkin T, Owen J, Astheimer L, Tapsell L, Howe PRC, 'The hypocholesterolaemic effect of chronic soy consumption may be linked to equol', Soy and Health 2002, Garant, Antwerp, Belgium 53-61 (2002) [B1]
1989Howe PRC, 'Effects of chronic enalapril treatment on plasma catecholamines, vasopressor sensitivity and baroreflex function in stroke prone spontaneously hypertensive rats', Current advances in ACE inhibition, Churchill-Livingstone, Edinburgh 275-278 (1989) [B2]
1989Howe PRC, 'The Role of Salt', Televent 89 Factors Affecting the Choice of Therapy in Cardiovascular Disease, Medical Observer, Sydney 24-26 (1989) [B1]
1986Howe PRC, Smith RM, King RA, Osbome-White WS, Potter BJ, Field JB, 'Effect of thyroid hormone on the development of central noradrenergic mechanisms', Iodine nutrition, thyroxine, and brain development, TATA McGraw-Hill Publishing Company, New Delhi 168-180 (1986) [B1]
1983Howe PRC, Smith RM, King RA, 'Myelin Structures and Metabolism', Molecular aspects of neurological disorders, Academic Press, Sydney 221-229 (1983) [B1]
1982Howe PRC, Tumuls I, Wallman Y, Chalmers JP, 'Central adrenaline nerves in spontaneously hypertensive and stroke prone rats', Hypertensive Mechanisms: The Spontaneously Hypertensive Rat as a Model to Study Human Hypertension, Schatteur, Heidelberg 485-489 (1982) [B1]
1982Howe PRC, Stead BH, Chalmers JP, 'Central serotonin nerves in spontaneously hypertensive and DOCA salt hypertensive rats', Hypertensive Mechanisms: The Spontaneously Hypertensive Rat as a Model to Study Human Hypertension, Schatteur, Heidelberg 627-631 (1982) [B1]
1979Howe PRC, 'Cardiac and central histamine in spontaneously hypertensive and stroke prone rats', Nervous System and Hypertension, John Wiley & Sons, New York 244-251 (1979) [B1]
1979Howe PRC, Blessing WW, Chalmers JP, 'Catecholamine containing cell bodies in rabbit hindbrain', Catecholamines: Basic and Clinical Frontiers, Pergamon Press, New York 1301-1303 (1979) [B1]
1979Howe PRC, Chalmers JP, Provis JC, West MJ, 'Histamine in the heart and spinal cord of hypertensive rats', Catecholamines, basic and clinical frontiers, Pergamon Press, New York 1164-1166 (1979) [B1]
1975Howe PRC, Livett BG, Fenwick E, Austin L, 'An immunochemical approach to the transport of axonal vesicular proteins and their release from nerve terminals', Recent Advances in Myology, Excerpta Medica, Amsterdam 215-223 (1975) [B1]
Show 15 more chapters

Journal article (222 outputs)

YearCitationAltmetricsLink
2015Best T, Howe P, Bryan J, Buckley J, Scholey A, 'Acute effects of a dietary non-starch polysaccharide supplement on cognitive performance in healthy middle-aged adults', NUTRITIONAL NEUROSCIENCE, 18 76-86 (2015)
DOI10.1179/1476830513Y.0000000101Author URL
2015Fan C, Georgiou KR, McKinnon RA, Keefe DM, Howe PR, Xian CJ, 'Combination chemotherapy with cyclophosphamide, epirubicin and 5-fluorouracil causes trabecular bone loss, bone marrow cell depletion and marrow adiposity in female rats.', J Bone Miner Metab, (2015)
DOI10.1007/s00774-015-0679-xAuthor URL
2015Tsiros MD, Coates AM, Howe PR, Walkley J, Hills AP, Wood RE, Buckley JD, 'Adiposity is related to decrements in cardiorespiratory fitness in obese and normal-weight children.', Pediatr Obes, (2015)
DOI10.1111/ijpo.12037Author URL
2014Thomson RL, Coates AM, Howe PRC, Bryan J, Matsumoto M, Buckley JD, 'Increases in plasma lutein through supplementation are correlated with increases in physical activity and reductions in sedentary time in older adults', Nutrients, 6 974-984 (2014) [C1]

Cross-sectional studies have reported positive relationships between serum lutein concentrations and higher physical activity levels. The purpose of the study was to determine whe... [more]

Cross-sectional studies have reported positive relationships between serum lutein concentrations and higher physical activity levels. The purpose of the study was to determine whether increasing plasma lutein levels increases physical activity. Forty-four older adults (BMI, 25.3 ± 2.6 kg/m2; age, 68.8 ± 6.4 year) not meeting Australian physical activity guidelines (150 min/week of moderate to vigorous activity) were randomized to consume capsules containing 21 mg of lutein or placebo with 250 mL of full-cream milk per day for 4 weeks and encouraged to increase physical activity. Physical activity was assessed by self-report, pedometry and accelerometry (daily activity counts and sedentary time). Exercise self-efficacy was assessed by questionnaire. Thirty-nine participants competed the study (Lutein = 19, Placebo = 20). Lutein increased plasma lutein concentrations compared with placebo (p < 0.001). Absolute and percentage changes in plasma lutein were inversely associated with absolute (r = -0.36, p = 0.03) and percentage changes (r = -0.39, p = 0.02) in sedentary time. Percentage change in plasma lutein was positively associated with the percentage change in average daily activity counts (r = 0.36, p = 0.03). Exercise self-efficacy did not change (p = 0.16). Lutein increased plasma lutein, which was associated with increased physical activity and reduced sedentary time in older adults. Larger trials should evaluate whether Lutein can provide health benefits over the longer term. © 2014 by the authors; licensee MDPI, Basel, Switzerland.

DOI10.3390/nu6030974
2014Howe PRC, Buckley JD, Murphy KJ, Pettman T, Milte C, Coates AM, 'Relationship between erythrocyte omega-3 content and obesity is gender dependent', Nutrients, 6 1850-1860 (2014) [C1]

Epidemiological evidence of an inverse association between consumption of long-chain omega-3 polyunsaturated fatty acids (LC n-3 PUFA) and obesity has been conflicting, even thoug... [more]

Epidemiological evidence of an inverse association between consumption of long-chain omega-3 polyunsaturated fatty acids (LC n-3 PUFA) and obesity has been conflicting, even though studies in animal models of obesity and limited human trials suggest that LC n-3 PUFA consumption may contribute to weight loss. We used baseline data from a convenience sample of 476 adults (291 women, 185 men) participating in clinical trials at our Centre to explore relationships between erythrocyte levels of LC n-3 PUFA (a reliable indicator of habitual intake) and measures of adiposity, viz. body mass index (BMI), waist circumference (WC) and body fat (BF) assessed by dual-energy X-ray absorptiometry. Means ± SD of assessments were BMI: 34 ± 7 and 31 ± 5 kg/m2; WC: 105 ± 16 and 110 ± 13 cm; BF: 48 ± 5 and 35% ± 6% in women and men respectively. Erythrocyte levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) were similar in men and women while docosapentaenoic acid (DPA) was higher and EPA + DHA (Omega-3 Index) slightly lower in men than in women. Both DHA and EPA + DHA correlated inversely with BMI, WC and BF in women while DPA correlated inversely with BF in men. Quartile distributions and curvilinear regression of the Omega-3 Index versus BMI revealed a steep rise of BMI in the lower range of the Omega-3 Index in women, but no association in men. Thus the results highlight important gender differences in relationships of specific LC n-3 PUFA in erythrocytes to markers of adiposity. If these reflect causal relationships between LC n-3 PUFA consumption and risk of obesity, gender specific targeted interventions should be considered. © 2014 by the authors; licensee MDPI, Basel, Switzerland.

DOI10.3390/nu6051850
CitationsScopus - 2Web of Science - 2
2014Voravuthikunchai S, Howe P, 'Report on the fifth International Conference on Natural Products for Health and Beauty (NATPRO 5) held in Thailand, 6¿8th may, 2014', Nutrients, 6 4115-4164 (2014) [C3]
DOI10.3390/nu6104115
2014Lee AMC, Shandala T, Nguyen L, Muhlhausler BS, Chen K-M, Howe PR, Xian CJ, 'Effects of resveratrol supplementation on bone growth in young rats and microarchitecture and remodeling in ageing rats', Nutrients, 6 5871-5887 (2014) [C1]

Osteoporosis is a highly prevalent skeletal disorder in the elderly that causes serious bone fractures. Peak bone mass achieved at adolescence has been shown to predict bone mass ... [more]

Osteoporosis is a highly prevalent skeletal disorder in the elderly that causes serious bone fractures. Peak bone mass achieved at adolescence has been shown to predict bone mass and osteoporosis related risk fracture later in life. Resveratrol, a natural polyphenol compound, may have the potential to promote bone formation and reduce bone resorption. However, it is unclear whether it can aid bone growth and bone mass accumulation during rapid growth and modulate bone metabolism during ageing. Using rat models, the current study investigated the potential effects of resveratrol supplementation during the rapid postnatal growth period and in late adulthood (early ageing) on bone microarchitecture and metabolism. In the growth trial, 4-week-old male hooded Wistar rats on a normal chow diet were given resveratrol (2.5 mg/kg/day) or vehicle control for 5 weeks. In the ageing trial, 6-month-old male hooded Wistar rats were treated with resveratrol (20 mg/kg/day) or vehicle for 3 months. Treatment effects in the tibia were examined by µ-computer tomography ((J.-CT) analysis, bone histomorphometric measurements and reverse transcription-polymerase chain reaction (RT-PCR) gene expression analysis. Resveratrol treatment did not affect trabecular bone volume and bone remodeling indices in the youth animal model. Resveratrol supplementation in the early ageing rats tended to decrease trabecular bone volume, Sirt1 gene expression and increased expression of adipogenesis-related genes in bone, all of which were statistically insignificant. However, it decreased osteocalcin expression (p = 0.03). Furthermore, serum levels of bone resorption marker C-terminal telopeptides type I collagen (CTX-1) were significantly elevated in the resveratrol supplementation group (p = 0.02) with no changes observed in serum levels of bone formation marker alkaline phosphatase (ALP). These results in rat models suggest that resveratrol supplementation does not significantly affect bone volume during the rapid growth phase but may potentially have negative effects on male skeleton during early ageing.

DOI10.3390/nu6125871
2014Murphy KJ, Parker B, Dyer KA, Davis CR, Coates AM, Buckley JD, Howe PR, 'A comparison of regular consumption of fresh lean pork, beef and chicken on body composition: a randomized cross-over trial.', Nutrients, 6 682-696 (2014) [C1]
DOI10.3390/nu6020682Author URL
2014Wong R, Garg M, Wood L, Howe P, 'Antihypertensive Potential of Combined Extracts of Olive Leaf, Green Coffee Bean and Beetroot: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial', Nutrients, 6 4881-4894 (2014) [C1]
DOI10.3390/nu6114881
Co-authorsRachel Wong, Manohar Garg, Lisa Wood
2014O'Callaghan N, Parletta N, Milte CM, Benassi-Evans B, Fenech M, Howe PRC, 'Telomere shortening in elderly individuals with mild cognitive impairment may be attenuated with ¿-3 fatty acid supplementation: A randomized controlled pilot study', Nutrition, 30 489-491 (2014) [C1]

Objectives: Excessive shortening of the telomeric ends of chromosomes is a marker of accelerated aging. Oxidative stress and nutritional deficiency may influence this process. The... [more]

Objectives: Excessive shortening of the telomeric ends of chromosomes is a marker of accelerated aging. Oxidative stress and nutritional deficiency may influence this process. The aim of this study was to investigate the effect of ¿-3 polyunsaturated fatty acid (¿-3 PUFA) supplementation on telomeric shortening in elderly individuals with mild cognitive impairment (MCI). Methods: Thirty-three adults ages > 65 y with MCI were randomized to receive a supplement rich in the long-chain ¿-3 PUFAs eicosapentaenoic acid (EPA; 1.67 g EPA + 0.16 g docosahexaenoic acid DHA/d; n = 12) or DHA (1.55 g DHA + 0.40 g EPA/d; n = 12), versus ¿-6 PUFA linoleic acid (LA; 2.2 g/d; n = 9) for 6 mo. Results: The intervention did not show an increase in telomere length with treatment and there was a trend toward telomere shortening during the intervention period. Linear mixed modeling produced a robust model although statistically underpowered. Telomere shortening was greatest in the LA group (d = 0.21) than in the DHA (d = 0.12) and EPA groups (d = 0.06). Increased erythrocyte DHA levels were associated with reduced telomere shortening (r = -0.67; P = 0.02) in the DHA group. Conclusion: Telomeric shortening may be attenuated by ¿-3 PUFA supplementation, requiring further investigation in larger samples. © 2014.

DOI10.1016/j.nut.2013.09.013
CitationsScopus - 4Web of Science - 3
2014Barbour JA, Howe PRC, Buckley JD, Wright GC, Bryan J, Coates AM, 'Lower energy intake following consumption of Hi-oleic and regular peanuts compared with iso-energetic consumption of potato crisps', Appetite, 82 124-130 (2014) [C1]

Snack foods can contribute a high proportion of energy intake to the diet. Peanuts are a snack food rich in unsaturated fatty acids, protein and fibre which have demonstrated sati... [more]

Snack foods can contribute a high proportion of energy intake to the diet. Peanuts are a snack food rich in unsaturated fatty acids, protein and fibre which have demonstrated satiety effects and may reduce total energy intake, despite their high energy density. This study examined the effects of consuming Hi-oleic (oleic acid ~75% of total fatty acids) peanuts and regular peanuts (oleic acid ~50% and higher in polyunsaturated fatty acids) compared with a high carbohydrate snack (potato crisps) on satiety and subsequent energy intake. Using a triple crossover study design, 24 participants (61 ± 1 years) consumed iso-energetic amounts (56-84 g) of Hi-oleic or regular peanuts or (60-90 g) potato crisps after an overnight fast. Hunger and satiety were assessed at baseline, 30, 60, 120 and 180 minutes following snack consumption using visual analogue scales, after which a cold buffet meal was freely consumed and energy intake measured. The same snack was consumed on 3 subsequent days with energy intake assessed from dietary records. This protocol was repeated weekly with each snack food. Total energy intake was lower following consumption of Hi-oleic and regular peanuts compared with crisps, both acutely during the buffet meal (-21%; p <.001 and -17%; p <.01) and over the 4 days (-11%; p <.001 and -9%; p <.01). Despite these reductions in energy intake, no differences in perceived satiety were observed. The findings suggest peanuts may be a preferred snack food to include in the diet for maintaining a healthy weight.

DOI10.1016/j.appet.2014.07.015
2014Raghu Nadhanan R, Fan C-M, Su Y-W, Howe PRC, Xian CJ, 'Fish oil in comparison to folinic acid for protection against adverse effects of methotrexate chemotherapy on bone', Journal of Orthopaedic Research, 32 587-596 (2014) [C1]

Methotrexate (MTX) chemotherapy is known to cause bone loss which lacks specific preventative treatments, although clinically folinic acid is often used to reduce MTX toxicity in ... [more]

Methotrexate (MTX) chemotherapy is known to cause bone loss which lacks specific preventative treatments, although clinically folinic acid is often used to reduce MTX toxicity in soft tissues. This study investigated damaging effects of MTX injections (0.75 mg/kg/day for 5 days) in rats and potential protective benefits of fish oil (0.25, 0.5, or 0.75 ml/100 g/day) in comparison to folinic acid (0.75 mg/kg) in the tibial metaphysis. MTX treatment significantly reduced height of primary spongiosa and volume of trabecular bone while reducing density of osteoblasts. Consistently, MTX reduced osteogenic differentiation but increased adipogenesis of bone marrow stromal cells, accompanied by lower mRNA expression of osteogenic transcription factors Runx2 and Osx, but an up-regulation of adipogenesis-related genes FABP4 and PPAR-¿. MTX also increased osteoclast density, bone marrow osteoclast formation, and mRNA expression of proinflammatory cytokines IL-1, IL-6, TNF-a, and RANKL/OPG ratio in bone. Fish oil (0.5 or 0.75 ml/100 g) or folinic acid supplementation preserved bone volume, osteoblast density, and osteogenic differentiation, and suppressed MTX-induced cytokine expression, osteoclastogenesis, and adipogenesis. Thus, fish oil at 0.5 ml/100 g or above is as effective as folinic acid in counteracting MTX-induced bone damage, conserving bone formation, suppressing resorption and marrow adiposity, suggesting its therapeutic potential in preventing bone loss during MTX chemotherapy. © 2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 32:587-596, 2014. © 2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

DOI10.1002/jor.22565
CitationsScopus - 1Web of Science - 1
2014Tsiros MD, Buckley JD, Howe PRC, Walkley J, Hills AP, Coates AM, 'Musculoskeletal pain in obese compared with healthy-weight children', Clinical Journal of Pain, 30 583-588 (2014) [C1]

OBJECTIVES:: To investigate whether obesity is associated with musculoskeletal pain in children. MATERIALS AND METHODS:: Obese (n=107) and healthy-weight (n=132) 10-to 13-year-old... [more]

OBJECTIVES:: To investigate whether obesity is associated with musculoskeletal pain in children. MATERIALS AND METHODS:: Obese (n=107) and healthy-weight (n=132) 10-to 13-year-old children (132 males, 107 females) participated in an observational case-control study. Children self-reported pain location (excluding abdominal pain), pain intensity (current and prior week), and pain prevalence (overall and lower limb) using the Pediatric Pain Questionnaire. Body composition was assessed (dual-energy x-ray absorptiometry) and children wore an accelerometer for 8 days. RESULTS:: After adjustment for accelerometry (weekly average counts per hour) and socioeconomic status, obese children had more intense pain (worst pain, P=0.006), pain in more locations (P=0.005), and a higher prevalence of lower limb pain (60% vs. 52% respectively, P=0.012) than healthy-weight children. Significant relationships were observed between body mass index and total pain locations (P=0.004, unadjusted and adjusted) and worst pain intensity (P=0.009, adjusted for socioeconomic status/accelerometry). There were no significant relationships between percent body fat and pain variables (unadjusted/adjusted analyses, P=0.262 to 1.0). DISCUSSION:: Obesity in children was associated with increased overall and lower limb musculoskeletal pain, for which body mass index was a stronger predictor than adiposity. Clinicians treating obese children should screen for pain and prescribe exercise programs that take their symptoms into account. Copyright © 2013 by Lippincott Williams & Wilkins.

DOI10.1097/AJP.0000000000000017
CitationsScopus - 1
2014O'Callaghan N, Parletta N, Milte CM, Benassi-Evans B, Fenech M, Howe PRC, 'Telomere shortening in elderly individuals with mild cognitive impairment may be attenuated with ¿-3 fatty acid supplementation: A randomized controlled pilot study', Nutrition, 30 489-491 (2014)
DOI10.1016/j.nut.2013.09.013
CitationsScopus - 3
2014Barbour JA, Howe PRC, Buckley JD, Bryan J, Coates AM, 'Nut consumption for vascular health and cognitive function', Nutrition Research Reviews, 27 131-158 (2014)
DOI10.1017/S0954422414000079
2014Barbour JA, Howe PRC, Buckley JD, Bryan J, Coates AM, 'Nut consumption for vascular health and cognitive function', Nutrition Research Reviews, 27 131-158 (2014) [C1]

Nuts are rich in many nutrients that can benefit multiple cardiometabolic functions, including arterial compliance, blood pressure, inflammation, glucoregulation and endothelial v... [more]

Nuts are rich in many nutrients that can benefit multiple cardiometabolic functions, including arterial compliance, blood pressure, inflammation, glucoregulation and endothelial vasodilatation. Impaired vasodilatation may contribute to impaired cognitive performance due to poor cerebral perfusion. The present narrative review examines associations between nut consumption, vascular health and cognitive function. It includes a systematic search which identified seventy-one epidemiological or intervention studies in which effects of chronic nut consumption on blood pressure, glucoregulation, endothelial vasodilator function, arterial compliance, inflammatory biomarkers and cognitive performance were evaluated. Weighted mean changes were estimated where data were available; they indicate that nut consumption reduces blood pressure and improves glucoregulation, endothelial vasodilator function and inflammation, whilst a limited number of studies suggest that nut consumption may also improve cognitive performance. Further clinical trials are warranted to explore relationships between nut consumption, endothelial function and cognitive function. © 2014 The Authors.

DOI10.1017/S0954422414000079
2014Nelson MJ, Thomson RL, Rogers DK, Howe PRC, Buckley JD, 'Maximal rate of increase in heart rate during the rest-exercise transition tracks reductions in exercise performance when training load is increased', JOURNAL OF SCIENCE AND MEDICINE IN SPORT, 17 129-133 (2014)
DOI10.1016/j.jsams.2013.02.016Author URL
2014Nelson MJ, Thomson RL, Rogers DK, Howe PRC, Buckley JD, 'Maximal rate of increase in heart rate during the rest-exercise transition tracks reductions in exercise performance when training load is increased', JOURNAL OF SCIENCE AND MEDICINE IN SPORT, 17 129-133 (2014) [C1]
DOI10.1016/j.jsams.2013.02.016Author URL
2014Wong RHX, Scholey A, Howe PRC, 'Assessing Premorbid Cognitive Ability in Adults With Type 2 Diabetes Mellitus-a Review With Implications for Future Intervention Studies', CURRENT DIABETES REPORTS, 14 (2014) [C1]
DOI10.1007/s11892-014-0547-4Author URL
Co-authorsRachel Wong
2014Howe P, Buckley J, 'Metabolic Health Benefits of Long-Chain Omega-3 Polyunsaturated Fatty Acids', MILITARY MEDICINE, 179 138-143 (2014) [C1]
DOI10.7205/MILMED-D-14-00154Author URL
2014Fuller JT, Thomson RL, Howe PRC, Buckley JD, 'Vibration Therapy Is No More Effective Than the Standard Practice of Massage and Stretching for Promoting Recovery From Muscle Damage After Eccentric Exercise', Clinical Journal of Sport Medicine, (2014)
DOI10.1097/JSM.0000000000000149
2014Thomson RL, Bellenger CR, Howe PRC, Karavirta L, Buckley JD, 'Improved heart rate recovery despite reduced exercise performance following heavy training: A within-subject analysis', Journal of Science and Medicine in Sport, (2014)

Objectives: The recovery of heart rate (HRR) after exercise is a potential indicator of fitness which has been shown to respond to changes in training. This study investigated the... [more]

Objectives: The recovery of heart rate (HRR) after exercise is a potential indicator of fitness which has been shown to respond to changes in training. This study investigated the within-individual association between HRR and exercise performance following three different training loads. Design: 11 male cyclists/triathletes were tested after two weeks of light training, two weeks of heavy training and two days of rest. Methods: Exercise performance was measured using a 5-min maximal cycling time-trial. HRR was measured over 60. s during supine recovery. Results: Exercise performance decreased 2.2. ±. 2.5% following heavy training compared with post-light training (p = 0.01), and then increased 4.0. ±. 4.2% following rest (p = 0.004). Most HRR indices indicated a more rapid recovery of heart rate (HR) following heavy training, and reverted to post light training levels following two days of rest. HRR indices did not differ between post-light training and after the rest period (p . > 0.6). There were inverse within-subject relationships between indices of HRR and performance (r = -0.6, . p . =. 0.004). Peak HR decreased 3.2. ±. 5.1. bpm following heavy training (p = 0.06) and significantly increased 4.9. ±. 4.3. bpm following recovery (p = 0.004). There was a moderate within-subject relationship between peak HR and exercise performance (r = 0.7, . p . =. 0.001). Controlling for peak HR reduced the relationships between HRR and performance (r = -0.4-0.5, . p . <. 0.05). Conclusions: This study demonstrated that HRR tracks short-term changes in exercise performance within-individuals, such that increases in HRR are associated with poorer exercise performance following heavy training. Peak HR can be compromised under conditions of fatigue, and needs to be taken into account in HRR analyses.

DOI10.1016/j.jsams.2015.02.010
2013Murphy KJ, Crichton GE, Dyer KA, Coates AM, Pettman TL, Milte C, et al., 'Dairy foods and dairy protein consumption is inversely related to markers of adiposity in obese men and women', Nutrients, 5 4665-4684 (2013) [C1]

A number of intervention studies have reported that the prevalence of obesity may be in part inversely related to dairy food consumption while others report no association. We sou... [more]

A number of intervention studies have reported that the prevalence of obesity may be in part inversely related to dairy food consumption while others report no association. We sought to examine relationships between energy, protein and calcium consumption from dairy foods (milk, yoghurt, cheese, dairy spreads, ice-cream) and adiposity including body mass index (BMI), waist (WC) and hip circumference (HC), and direct measures of body composition using dual energy X-ray absorptiometry (% body fat and abdominal fat) in an opportunistic sample of 720 overweight/obese Australian men and women. Mean (SD) age, weight and BMI of the population were 51 ± 10 year, 94 ± 18 kg and 32.4 ± 5.7 kg/m2, respectively. Reduced fat milk was the most commonly consumed dairy product (235 ± 200 g/day), followed by whole milk (63 ± 128 g/day) and yoghurt (53 ± 66 g/day). Overall dairy food consumption (g/day) was inversely associated with BMI, % body fat and WC (all p < 0.05). Dairy protein and dairy calcium (g/day) were both inversely associated with all adiposity measures (all p < 0.05). Yoghurt consumption (g/day) was inversely associated with % body fat, abdominal fat, WC and HC (all p < 0.05), while reduced fat milk consumption was inversely associated with BMI, WC, HC and % body fat (all p < 0.05). Within a sample of obese adults, consumption of dairy products, dairy protein, and calcium was associated with more favourable body composition. © 2013 by the authors; licensee MDPI, Basel, Switzerland.

DOI10.3390/nu5114665
CitationsScopus - 3Web of Science - 3
2013Murphy K, Howe P, 'Proceedings of the 2013 meeting of the Australasian Section of the American Oil Chemists Society (AAOCS)', Nutrients, 5 5065-5096 (2013) [C3]
DOI10.3390/nu5125065
CitationsScopus - 1Web of Science - 1
2013Meyer BJ, Grenyer BFS, Crowe T, Owen AJ, Grigonis-Deane EM, Howe PRC, 'Improvement of Major Depression is Associated with Increased Erythrocyte DHA', Lipids, 48 863-868 (2013) [C1]

The aim of this study was to determine if changes in omega-3 polyunsaturated fatty acid status following tuna oil supplementation correlated with changes in scores of depression. ... [more]

The aim of this study was to determine if changes in omega-3 polyunsaturated fatty acid status following tuna oil supplementation correlated with changes in scores of depression. A total of 95 volunteers receiving treatment for major depression were randomised to consume 8 × 1 g capsules per day of HiDHA (2 g DHA, 0.6 g EPA and 10 mg Vitamin E) or olive oil (placebo) for 16 weeks, whilst undergoing weekly counseling sessions by trained clinical psychologists using a standard empirically validated psychotherapy. Depression status was assessed using the 17 item Hamilton rating scale for depression and the Beck Depression Inventory by a psychodiagnostician who was blind to the treatment. Blood was taken at baseline and 16 weeks (n = 48) for measurement of erythrocyte fatty acids. With HiDHA supplementation, erythrocyte DHA content rose from 4.1 ± 0.2 to 7.9 ± 0.4 % (mean ± SEM, p < 0.001) of total fatty acids but did not change (4.0 ± 0.2 to 4.1 ± 0.2 %) in the olive oil group. The mean changes in scores of depression did not differ significantly between the two groups (-12.2 ± 2.1 for tuna oil and -14.4 ± 2.3 for olive oil). However, analysis of covariance showed that in the fish oil group there was a significant correlation (r = -0.51) between the change in erythrocyte DHA and the change in scores of depression (p < 0.05). Further study of the relationship between DHA and depression is warranted. © 2013 AOCS.

DOI10.1007/s11745-013-3801-7
CitationsScopus - 8Web of Science - 6
2013Wong RHX, Coates AM, Buckley JD, Howe PR, 'Evidence for circulatory benefits of resveratrol in humans', Annals of the New York Academy of Sciences, 1290 52-58 (2013) [C1]
CitationsScopus - 2Web of Science - 3
Co-authorsRachel Wong
2013Wong RHX, Berry NM, Coates AM, Buckley JD, Bryan J, Kunz I, Howe PRC, 'Chronic resveratrol consumption improves brachial flow-mediated dilatation in healthy obese adults', Journal of Hypertension, 31 1819-1827 (2013) [C1]

Background: We have previously demonstrated acute dose-dependent increases of flow-mediated dilatation (FMD) in the brachial artery after resveratrol consumption in mildly hyperte... [more]

Background: We have previously demonstrated acute dose-dependent increases of flow-mediated dilatation (FMD) in the brachial artery after resveratrol consumption in mildly hypertensive, overweight/obese adults. Resveratrol supplementation has also been shown to increase cerebral blood flow acutely, without affecting cognition. Objectives: To evaluate the effects of chronic resveratrol supplementation on both FMD and cognitive performance. Method: Twenty-eight obese but otherwise healthy adults (BMI: 33.3±0.6kg/m 2) were randomized to take a single 75 mg capsule of trans-resveratrol (Resvida) or placebo daily for 6 weeks each in a double-blind crossover supplementation trial. Blood pressure, arterial compliance, FMD, and performance on the Stroop Color-Word Test were assessed at the end of each 6-week intervention period while fasted and at least 18 h after taking the last daily capsule. An additional capsule of the same supplement was then taken. FMD assessment was repeated 1 h later. Results: Chronic resveratrol supplementation for 6 weeks was well tolerated and resulted in a 23% increase in FMD compared with placebo (P = 0.021, paired t-test). The extent of increase correlated negatively with baseline FMD (r= -0.47, P=0.01). A single dose of resveratrol (75 mg) following chronic resveratrol supplementation resulted in a 35% greater acute FMD response than the equivalent placebo supplementation. These FMD improvements remained significant after adjusting for baseline FMD. Blood pressure, arterial compliance, and all components of the Stroop Color-Word Test were unaffected by chronic resveratrol supplementation. Conclusion: Daily resveratrol consumption was well tolerated and has the potential to maintain healthy circulatory function in obese adults. © 2013 Wolters Kluwer Health Lippincott Williams & Wilkins.

DOI10.1097/HJH.0b013e328362b9d6
CitationsScopus - 13Web of Science - 14
Co-authorsRachel Wong
2013Wong RHX, Howe PR, Buckley JD, Coates AM, Berry NM, 'Chronic consumption of a wild green oat extract (Neuravena) improves brachial flow-mediated dilatation and cerebrovascular responsiveness in older adults', Journal of Hypertension, 31 192-200 (2013) [C1]
CitationsScopus - 3Web of Science - 3
Co-authorsRachel Wong
2013Meyer BJ, Kolanu N, Griffiths DA, Grounds B, Howe PRC, Kreis IA, 'Food groups and fatty acids associated with self-reported depression: An analysis from the Australian National Nutrition and Health Surveys', NUTRITION, 29 1042-1047 (2013) [C1]
DOI10.1016/j.nut.2013.02.006Author URL
CitationsScopus - 6Web of Science - 6
2013O'Callaghan N, Benassi-Evans B, Fenech M, Parletta N, Milte CM, Howe PRC, 'Telomere shortening in elderly individuals with mild cognitive impairment may be attenuated with ¿-3 fatty acid supplementation: A randomized controlled pilot study', Nutrition, (2013) [C1]

Objectives: Excessive shortening of the telomeric ends of chromosomes is a marker of accelerated aging. Oxidative stress and nutritional deficiency may influence this process. The... [more]

Objectives: Excessive shortening of the telomeric ends of chromosomes is a marker of accelerated aging. Oxidative stress and nutritional deficiency may influence this process. The aim of this study was to investigate the effect of ¿-3 polyunsaturated fatty acid (¿-3 PUFA) supplementation on telomeric shortening in elderly individuals with mild cognitive impairment (MCI). Methods: Thirty-three adults ages > 65 y with MCI were randomized to receive a supplement rich¿in the long-chain ¿-3 PUFAs eicosapentaenoic acid (EPA; 1.67 g EPA + 0.16 g docosahexaenoic acid DHA/d; n = 12) or DHA (1.55 g DHA + 0.40 g EPA/d; n = 12), versus ¿-6 PUFA linoleic acid (LA;¿2.2 g/d; n = 9) for 6 mo. Results: The intervention did not show an increase in telomere length with treatment and there was a trend toward telomere shortening during the intervention period. Linear mixed modeling produced a robust model although statistically underpowered. Telomere shortening was greatest in the LA group (d = 0.21) than in the DHA (d = 0.12) and EPA groups (d = 0.06). Increased erythrocyte DHA levels were associated with reduced telomere shortening (r = -0.67; P = 0.02) in the DHA group. Conclusion: Telomeric shortening may be attenuated by ¿-3 PUFA supplementation, requiring further investigation in larger samples. Crown Copyright © 2013.

DOI10.1016/j.nut.2013.09.013
CitationsScopus - 4Web of Science - 3
2013Tsiros MD, Coates AM, Howe PRC, Grimshaw PN, Walkley J, Shield A, et al., 'Knee extensor strength differences in obese and healthy-weight 10-to 13-year-olds', EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, 113 1415-1422 (2013) [C1]
DOI10.1007/s00421-012-2561-zAuthor URL
CitationsScopus - 5Web of Science - 3
2013Fuller JT, Thomson RL, Howe PRC, Buckley JD, 'Effect of vibration on muscle perfusion: a systematic review', CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING, 33 1-10 (2013) [C1]
DOI10.1111/j.1475-097X.2012.01161.xAuthor URL
CitationsScopus - 3Web of Science - 2
2013Fulton AS, Hill AM, Williams MT, Howe PR, Frith PA, Wood LG, et al., 'Feasibility of omega-3 fatty acid supplementation as an adjunct therapy for people with chronic obstructive pulmonary disease: study protocol for a randomized controlled trial', TRIALS, 14 (2013) [C3]
DOI10.1186/1468-6708-14-107Author URL
CitationsScopus - 4Web of Science - 3
Co-authorsLisa Wood, Manohar Garg
2013Nadhanan RR, Skinner J, Chung R, Su Y-W, Howe PR, Xian CJ, 'Supplementation with Fish Oil and Genistein, Individually or in Combination, Protects Bone against the Adverse Effects of Methotrexate Chemotherapy in Rats', PLOS ONE, 8 (2013) [C1]
DOI10.1371/journal.pone.0071592Author URL
CitationsScopus - 4Web of Science - 3
2013Tsiros MD, Buckley JD, Howe PRC, Olds T, Walkley J, Taylor L, et al., 'Day-to-day physical functioning and disability in obese 10-to 13-year-olds', PEDIATRIC OBESITY, 8 31-41 (2013) [C1]
DOI10.1111/j.2047-6310.2012.00083.xAuthor URL
CitationsScopus - 5Web of Science - 3
2013McDonnell MN, Berry NM, Cutting MA, Keage HA, Buckley JD, Howe PRC, 'Transcranial Doppler ultrasound to assess cerebrovascular reactivity: reliability, reproducibility and effect of posture', PEERJ, 1 (2013)
DOI10.7717/peerj.65Author URL
CitationsScopus - 5Web of Science - 5
2012Howe P, 'Acknowledgment of reviewers', Nutrients, 4 151-153 (2012)
DOI10.3390/nu4030151
2012Crichton GE, Murphy KJ, Howe PRC, Buckley JD, Bryan J, 'Dairy consumption and working memory performance in overweight and obese adults', Appetite, 59 34-40 (2012) [C1]
CitationsScopus - 7Web of Science - 5
2012Milte C, Sinn N, Buckley JD, Coates AM, Young R, Howe PRC, 'Eicosapentaenoic and docosahexaenoic acid, cognition and behaviour in children with ADHD: A randomised controlled trial', Nutrition, 28 670-677 (2012) [C1]
CitationsScopus - 31Web of Science - 31
2012Haren MT, Misan G, Paterson T-J, Ruffin RE, Grant JF, Buckley JD, et al., 'Abdominal adiposity and obstructive airway disease: testing insulin resistance and sleep disordered breathing mechanisms', BMC PULMONARY MEDICINE, 12 (2012) [C1]
DOI10.1186/1471-2466-12-31Author URL
CitationsScopus - 1Web of Science - 1
2012Crichton GE, Howe PRC, Buckley JD, Coates AM, Murphy KJ, 'Dairy consumption and cardiometabolic health: outcomes of a 12-month crossover trial', Nutrition and Metabolism, 9 19-29 (2012) [C1]
CitationsScopus - 21Web of Science - 18
2012Crichton GE, Howe PRC, Buckley JD, Coates AM, Murphy KJ, Bryan J, 'Long-term dietary intervention trials: critical issues and challenges', TRIALS, 13 (2012) [C1]
DOI10.1186/1745-6215-13-111Author URL
CitationsScopus - 4Web of Science - 5
2012Haren MT, Misan G, Grant J, Buckley JD, Howe PRC, Taylor AW, et al., 'Proximal correlates of metabolic phenotypes during 'at-risk' and 'case' stages of the metabolic disease continuum', Nutrition and Diabetes, 2 24-24 (2012) [C1]
CitationsScopus - 3Web of Science - 3
2012Howe P, 'The Australian Paradox', NUTRIENTS, 4 258-258 (2012) [C3]
DOI10.3390/nu4040258Author URL
2012Murphy KJ, Thomson RL, Coates AM, Buckley JD, Howe PRC, 'Effects of Eating Fresh Lean Pork on Cardiometabolic Health Parameters', NUTRIENTS, 4 711-723 (2012) [C2]
DOI10.3390/nu4070711Author URL
CitationsScopus - 8Web of Science - 6
2012Wong RHX, Howe PRC, Bryan J, Coates A, Buckley J, Berry N, 'Chronic effects of a wild green oat extract supplementation on cognitive performance in older adults: A randomised, double-blind, placebo-controlled crossover trial', Nutrients, 4 331-342 (2012) [C1]
CitationsScopus - 2Web of Science - 2
Co-authorsRachel Wong
2011Sinn N, Milte C, Street SJ, Buckley JD, Coates AM, Petkov J, Howe PRC, 'Effects of omega-3 fatty acids EPA versus DHA on depressive symptoms, quality of life, memory and executive function in older adults with mild cognitive impairment: A 6-month randomised controlled trial', The British Journal of Nutrition: an international journal of nutritional science, - 1-12 (2011) [C1]
CitationsScopus - 52Web of Science - 56
2011Wong RHX, Howe PR, Buckley JD, Coates AM, Kunz I, Berry NM, 'Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure', Nutrition Metabolism and Cardiovascular Diseases, 21 851-856 (2011) [C1]
DOI10.1016/j.numecd.2010.03.003
CitationsScopus - 91Web of Science - 83
Co-authorsRachel Wong
2011Milte C, Sinn N, Street SJ, Buckley JD, Coates AM, Howe PRC, 'Erythrocyte polyunsaturated fatty acid status, memory, cognition and mood in older adults with mild cognitive impairment and healthy controls', Prostaglandins Leukotrienes and Essential Fatty Acids, 84 153-161 (2011) [C1]
CitationsScopus - 17Web of Science - 16
2011Berry NM, Robinson MJ, Bryan J, Murphy KJ, Buckley JD, Howe PRC, 'Acute effects of an Avena sativa herb extract on responses to the Stroop colour word test', Journal of Alternative and Complementary Medicine, 17 635-637 (2011) [C1]
CitationsScopus - 5Web of Science - 4
2011Milte C, Sinn N, Buckley JD, Coates AM, Howe PRC, 'Polyunsaturated fatty acids, cognition and literacy in children with ADHD with and without learning difficulties', Journal of Child Health Care, 15 299-311 (2011) [C1]
CitationsScopus - 11Web of Science - 11
2010Sinn N, Milte C, Howe PRC, 'Oiling the Brain: A Review of Randomized Controlled Trials of Omega-3 Fatty Acids in Psychopathology across the Lifespan', NUTRIENTS, 2 128-170 (2010) [C3]
DOI10.3390/nu2020128Author URL
CitationsScopus - 26Web of Science - 29
2010Sinn N, Milte C, Howe PRC, 'A review of randomised controlled trials of omega-3 fatty acids in psychopathology across the lifespan', Nutrients, 2 128-170 (2010) [C1]
2010Buckley JD, Howe PRC, 'Long-Chain Omega-3 Polyunsaturated Fatty Acids May Be Beneficial for Reducing Obesity - A Review', Nutrients, 2 1212-1230 (2010) [C1]
CitationsScopus - 55Web of Science - 52
2010Davison K, Bircher S, Hill A, Coates AM, Howe PRC, Buckley JD, 'Relationships between Obesity, Cardiorespiratory Fitness, and Cardiovascular Function', Journal of Obesity, 2010 1-7 (2010) [C1]
DOI10.1155/2010/191253
CitationsScopus - 11
2010Sjoberg N, Milte CM, Buckley JD, Howe PRC, Coates AM, Saint DA, 'Dose-dependent increases in heart rate variability and arterial compliance in overweight and obese adults with DHA-rich fish oil supplementation', The British Journal of Nutrition: an international journal of nutritional science, 103 243-248 (2010) [C1]
CitationsScopus - 15Web of Science - 14
2010Berry NM, Davison K, Coates AM, Buckley JD, Howe PRC, 'Impact of cocoa flavanol consumption on blood pressure responsiveness to exercise', The British Journal of Nutrition: an international journal of nutritional science, 103 1-5 (2010) [C1]
CitationsScopus - 24Web of Science - 22
2010Head GA, Mihailidou AS, Duggan KA, Beilin LJ, Berry N, Brown MA, et al., 'Relationship between ambulatory and clinic blood pressure: Defining diagnostic and treatment targets', The British Journal of Nutrition: an international journal of nutritional science, 340 1104-1104 (2010) [C1]
2010Davison K, Berry NM, Misan G, Coates AM, Buckley JD, Howe PRC, 'Dose-related effects of flavanol-rich cocoa on blood pressure', Journal of Human Hypertension, 24 568-576 (2010) [C1]
CitationsScopus - 23Web of Science - 18
2010Head GA, Mihailidou AS, Duggan KA, Beilin LJ, Berry N, Brown MA, et al., 'Definition of ambulatory blood pressure targets for diagnosis and treatment of hypertension in relation to clinic blood pressure: prospective cohort study', BRITISH MEDICAL JOURNAL, 340 (2010) [C1]
DOI10.1136/bmj.c1104Author URL
CitationsScopus - 61Web of Science - 39
2010Buckley JD, Thomson RL, Coates AM, Howe PRC, Denichilo MO, Rowney MK, 'Supplementation with a whey protein hydrolysate enhances recovery of muscle force-generating capacity following eccentric exercise', Journal of Science and Medicine in Sport, 13 178-181 (2010) [C1]
CitationsScopus - 19Web of Science - 16
2009Buckley JD, Howe PRC, 'Anti-obesity effects of long chain omega-3 polyunsaturated fatty acids', Obesity Reviews, 10 648-659 (2009) [C1]
CitationsScopus - 63Web of Science - 57
2009Pettman TL, Buckley JD, Misan GM, Coates AM, Howe PRC, 'Health benefits of a 4-month group-based diet and lifestyle modification program for individuals with metabolic syndrome', Obesity Research and Clinical Practice, 3 221-235 (2009) [C1]
CitationsScopus - 3Web of Science - 3
2009Howe P, 'Why Nutrients?', NUTRIENTS, 1 1-2 (2009) [C3]
DOI10.3390/nu1010001Author URL
2009Coates AM, Sioutis S, Buckley JD, Howe PRC, 'Regular consumption of omega-3 fatty acid enriched pork modifies cardiovascular risk factors', The British Journal of Nutrition: an international journal of nutritional science, 101 592-597 (2009) [C1]
CitationsScopus - 17Web of Science - 14
2009Thorp AA, Sinn N, Buckley JD, Coates AM, Howe PRC, 'Soya isoflavone supplementation enhances spatial working memory in men', The British Journal of Nutrition: an international journal of nutritional science, 102 1348-1354 (2009) [C1]
CitationsScopus - 22Web of Science - 18
2009Bendyk A, Marino V, Zilm PS, Howe PRC, Bartold PM, 'Effect of dietary omega-3 polyunsaturated fatty acids on experimental periodontitis in the mouse.', Journal of Periodontal Research, 44 211-216 (2009) [C1]
CitationsScopus - 12Web of Science - 14
2009Milte C, Sinn N, Howe PRC, 'Polyunsaturated fatty acid status in ADHD, depression and Alzheimer's disease: towards an omega-3 index for mental health?', Nutrition Reviews, 67 573-590 (2009) [C1]
CitationsScopus - 23Web of Science - 21
2009Eslick G, Howe PRC, Smith C, Priest R, Bensoussan A, 'Benefits of Fish Oil Supplementation in Hyperlipidemia: A Systematic Review and Meta-Analysis', International Journal of Cardiology, 136 4-16 (2009) [C1]
CitationsScopus - 81Web of Science - 70
2009Tsiros MD, Olds T, Buckley JD, Grimshaw P, Brennan L, Walkley J, et al., 'Health-related quality of life in obese children and adolescents', International Journal of Obesity, 33 387-400 (2009) [C1]
CitationsScopus - 119Web of Science - 106
2009Buckley JD, Burgess S, Murphy KM, Howe PRC, 'DHA-rich fish oil lowers heart rate during submaximal exercise in elite Australian Rules footballers', Journal of Science and Medicine in Sport, 12 503-507 (2009) [C1]
CitationsScopus - 21Web of Science - 21
2008Mukaro VR, Costabile M, Murphy K, Howe PRC, Hii C, Ferrante A, 'Leukocyte numbers and function in subjects eating n-3 enriched foods: selective depression of natural killer cell levels1-3', Arthritis Research and Therapy, 10 57-57 (2008) [C1]
CitationsScopus - 7Web of Science - 7
2008Pettman TL, Misan GM, Coates AM, Owen K, Buckley JD, Howe PRC, 'Self-management for obesity and cardiometabolic fitness: Description and evaluation of the lifestyle intervention program of a randomised controlled trial', International Journal of Behavioral Nutrition and Physical Activity, 5 53-53 (2008) [C1]
CitationsScopus - 16Web of Science - 12
2008Pettman TL, Buckley JD, Coates AM, Misan GM, Petkov J, Howe PRC, 'Prevalence and interrelationships between cardio-metabolic risk factors in abdominally-obese individuals', Metabolic Sydnrome and Related Disorders, 7 31-36 (2008) [C1]
CitationsScopus - 4Web of Science - 3
2008Sinn N, Howe PRC, 'Mental health benefits of omega-3 fatty acids may be mediated by improvements in cerebral vascular function', Bioscience Hypotheses, 1 103-108 (2008) [C1]
CitationsScopus - 22
2008Tsiros M, Sinn N, Brennan L, Coates A, Walkely J, Petkov J, et al., 'Cognitive Behavioural Therapy improves diet and body composition in overweight and obese adolescents', American Journal of Clinical Nutrition, 87 1134-1140 (2008) [C1]
CitationsScopus - 41Web of Science - 29
2008Milte CM, Coates AM, Buckley JD, Hill AM, Howe PRC, 'Dose-dependent effects of docosahexaenoic acid-rich fish oil on erythrocyte docosahexaenoic acid and blood lipid levels', The British Journal of Nutrition: an international journal of nutritional science, 99 1083-1088 (2008) [C1]
CitationsScopus - 26Web of Science - 27
2008Howe PRC, Ninio DM, Hill AM, 'Docosahexaenoic acid-rich fish oil improves heart rate variability and heart rate responses to exercise in overweight adults', The British Journal of Nutrition: an international journal of nutritional science, 100 1097-1203 (2008) [C1]
CitationsScopus - 23Web of Science - 22
2008Peoples GE, McLennan PL, Howe PRC, Groeller H, 'Fish oil reduces heart rate and oxygen consumption during exercise', Journal of Cardiovascular Pharmacology, 52 540-547 (2008) [C1]
CitationsScopus - 58Web of Science - 54
2008Davison K, Coates AM, Buckley JD, Howe PRC, 'Effect of cocoa flavanols and exercise on cardio-metabolic risk factors in overweight and obese subjects', International Journal of Obesity, 32 1289-1296 (2008) [C1]
CitationsScopus - 63Web of Science - 55
2008Tsiros M, Sinn N, Coates A, Howe PRC, Buckley J, 'Treatment of adolescent overweight and obesity', European Journal of Pediatrics, 167 9-16 (2008) [C1]
CitationsScopus - 44Web of Science - 35
2008Murphy KJ, Saint DA, Howe PRC, 'Lack of effect of sugar cane and sunflower seed policosanols on plasma cholesterol in rabbits', Journal of the American College of Nutrition, 27 476-484 (2008) [C1]
CitationsScopus - 5Web of Science - 5
2008Thorp A, Howe PRC, Mori T, Coates A, Buckley J, Hodgson J, et al., 'Soy food consumption does not lower LDL-cholesterol in either equol or non-equol producers', Journal of the American College of Nutrition, 88 298-304 (2008) [C1]
CitationsScopus - 28Web of Science - 25
2008Sioutis S, Coates AM, Buckley JD, Murphy TW, Channon HA, Howe PRC, 'Omega-3 enrichment of pork with fishmeal: effects on production and consumer acceptability', European Journal of Lipid Science and Technology, 110 701-706 (2008) [C1]
CitationsScopus - 4Web of Science - 4
2007Coates AM, Buckley JD, Ross R, Thielecke F, Howe PRC, Hill AM, 'Can EGCG Reduce Abdominal Fat in Obese Subjects?', Journal of the American College of Nutrition, 26 396-402 (2007) [C1]
CitationsScopus - 53Web of Science - 50
2007Coates AM, Howe PRC, 'Edible nuts and metabolic health', Current Opinion in Lipidology, 18 25-30 (2007) [C1]
CitationsScopus - 30Web of Science - 30
2007Howe PRC, Buckley J, Meyer B, 'Long-chain omega-3 fatty acids in red meat', Nutrition and Dietetics, 64 135-139 (2007) [C1]
CitationsScopus - 23Web of Science - 23
2007Hill AM, Laforgia J, Coates AM, Buckley JD, Howe PRC, 'Estimating abdominal adipose tissue with DXA and anthropometry', Obesity, 15 504-510 (2007) [C1]
CitationsScopus - 38Web of Science - 35
2007Hill AM, Buckley JD, Murphy KJ, Howe PRC, 'Combining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factors', American Journal of Clinical Nutrition, 85 1267-1274 (2007) [C1]
CitationsScopus - 86Web of Science - 75
2007Murphy K, Mansour J, Patch C, Mori T, Meyer B, Tapsell L, et al., 'Impact of foods enriched with n-3 long-chain polyunsaturated fatty acids on erythrocyte n-3 levels and cardiovascular risk factors', The British Journal of Nutrition: an international journal of nutritional science, 97 749-757 (2007) [C1]
CitationsScopus - 66Web of Science - 60
2007Hill A, Worthley C, Murphy K, Buckley J, Ferrante A, Howe PRC, 'n-3 Fatty acid supplementation and regular moderate exercise: Differential effects of a combined intervention on neutrophil function', The British Journal of Nutrition: an international journal of nutritional science, 98 300-309 (2007) [C1]
CitationsScopus - 14Web of Science - 12
2007Meyer B, Hammervold T, Rustan A, Howe PRC, 'Dose-dependent effects of docosahexaenoic acid supplementation on blood lipids in statin-treated hyperlipidaemic subjects', Lipids, 42 109-115 (2007) [C1]
CitationsScopus - 26Web of Science - 25
2007Greyner B, Crowe T, Meyer B, Owen A, Grigonis-Deane E, Caputi P, Howe PRC, 'Fish oil supplementation in the treatment of major depression: a randomized double-blind placebo-controlled trial', Progress in Neuro-Psychopharmacology and Biological Psychiatry, 31 1393-1396 (2007) [C1]
CitationsScopus - 65Web of Science - 60
2006Buckley JD, Thorp AJ, Murphy KJ, Howe PRC, 'Dose-dependent inhibition of the post-prandial glycaemic response to a standard carbohydrate meal following incorporation of a-cyclodextrin', Annals of Nutrition and Metabolism: European journal of nutrition metabolic diseases and dietetics, 50 108-114 (2006) [C1]
CitationsScopus - 15Web of Science - 10
2006Howe PRC, Meyer BJ, Record S, Baghurst K, 'Dietary intake of long chain w-3 polyunsaturated fatty acids: contribution of meat sources', Nutrition, 22 47-53 (2006) [C1]
CitationsScopus - 155Web of Science - 149
2005Patch CS, Tapsell LC, Mori TA, Meyer BJ, Murphy KJ, Mansour J, et al., 'The use of novel foods enriched with long-chain n-3 fatty acids to increase dietary intake: a comparison of methodologies assessing nutrient intake', Journal of the American Dietetic Association, 105 1918-1926 (2005) [C1]
CitationsScopus - 20Web of Science - 17
2005Tenikoff D, Murphy KJ, Le M, Howe PRC, Howarth GS, 'Lyprinol (stabilised lipid extract of New Zealand green-lipped mussel): a potential preventative treatment modality for inflammatory bowel disease', Journal of Gastroenterology, 40 361-365 (2005) [C1]
CitationsScopus - 29Web of Science - 25
2005Ninio DM, Murphy KJ, Howe PRC, Saint DA, 'Dietary fish oil protects against stretch-induced vulnerability to atrial fibrillation in a rabbit mode', Journal of Cardiovascular Electrophysiology, 16 1189-1194 (2005) [C1]
CitationsScopus - 80Web of Science - 54
2004Meyer BJ, Larkin TA, Owen AJ, Astheimer LB, Tapsell LC, Howe PRC, 'Limited Lipid-Lowering Effects of Regular Consumption of Whole Soybean Foods', Annals of Nutrition and Metabolism: European journal of nutrition metabolic diseases and dietetics, 48 67-78 (2004) [C1]
CitationsScopus - 57Web of Science - 45
2004Howe PRC, Murphy KJ, 'Nutrients as Adjunct Therapy in Cardiovascular Risk Management. Current Medical Literature', Clinical Nutrition, 13 1-5 (2004) [C1]
2003Meyer BJ, Mann NJ, Lewis JL, Milligan G, Sinclair AJ, Howe PRC, 'Dietary intakes and food sources of omega-6 and omega-3 polyunsaturated fatty acids', Lipids, 38 391-398 (2003) [C1]
CitationsScopus - 238Web of Science - 218
2003Murphy SM, McAllen R, Campbell GD, Howe PRC, Anderson CR, 'Re-establishment of neurochemical coding of preganglionic neurons innervating transplanted targets', Neuroscience, 117 347-360 (2003) [C1]
CitationsScopus - 6Web of Science - 8
2003Howe PR, Meyer BJ, Record S, Baghurst K, 'Contribution of red meat to very long chain omega-3 fatty acid (VLCOmega3) intake.', Asia Pacific journal of clinical nutrition, 12 S27 (2003)
2003Murphy KJ, Mansour J, Patch CS, Weldon G, Ross D, Mori TA, et al., 'Development and evaluation of foods enriched with omega-3 fatty acids (Omega3) from fish oil.', Asia Pacific journal of clinical nutrition, 12 S35 (2003)
2003Mann NJ, Sinclair AJ, Percival P, Lewis JL, Meyer BJ, Howe PRC, 'Development of a database of fatty acids in Australian foods', Nutrition and Dietetics, 60 34-37 (2003) [C1]
2002Howe PRC, Downing J, Greyner B, Grigonis-Deane E, Bryden W, 'Tuna fishmeal as a source of docosahexaenoic acid for omega-3 enrichment of pork and chicken meat and eggs', Lipids, 37 1067-1076 (2002) [C1]
CitationsWeb of Science - 41
2002Howe PRC, Grigonis-Deane E, 'Omega-3 enrichment of chicken', Asia Pacific Journal of Clinical Nutrition, 11 (2002)
2002Howe PRC, 'Nutrient-drug synergies to optimise therapeutic benefit', Asia Pacific Journal of Clinical Nutrition, 11 (2002)
2002Meyer BJ, Larkin TA, Owen AJ, Astheimer LB, Tapsell LC, Howe PRC, 'Improvement in plasma lipid levels (including lipoprotein (a)) after chronic soy consumption may be linked to equol', Asia Pacific Journal of Clinical Nutrition, 11 (2002)
2002Howe PRC, 'The Omega Workshop Report', Food Australia, 54 505-506 (2002) [C1]
CitationsScopus - 1
2002Liu L, Howe PRC, Zhou Y-F, Hocart C, Zhang R, 'Fatty acid profiles of leaves of nine edible wild plants: An Australian study', Journal of Food Lipids, 9 65-71 (2002) [C1]
CitationsScopus - 12Web of Science - 7
2001Ridges L, Sunderland R, Moerman K, Meyer B, Astheimer L, Howe PRC, 'Cholesterol lowering benefits of soy and linseed enriched foods', Asia Pacific Journal of Clinical Nutrition, 10 204-211 (2001) [C1]
CitationsScopus - 25Web of Science - 20
2001Howe PRC, 'The salt story', Nutridate, 12 5-7 (2001) [C1]
2001Howe PRC, 'Nutritional intervention in the management of established cardiovascular risk factors', Medical Observer, 16 36-37 (2001) [C1]
2001Howe PRC, 'Fish, Omega-3 and stroke ¿ benefit, not risk', Perspectives in Food & Nutrition, 8 (2001) [C3]
2000Liu L, Howe PRC, Zhou Y-F, Xu Z-Q, Hocart C, Zhang R, 'Fatty Acids and ß-Carotene in Australian Purslane (Portulaca oleracea) Varieties', Journal of Chromatography A, 893 207-213 (2000) [C1]
CitationsScopus - 80Web of Science - 65
2000Howe PRC, 'What makes a functional food functional?', Asia Pacific Journal of Clinical Nutrition, 9 108-112 (2000) [C1]
CitationsScopus - 5Web of Science - 3
2000Anderson CR, Penkethman S, Howe PRC, Murphy SM, 'Rodent noradrenergic chromaffin cells contain calbindin d28k-immunoreactivity', Neuroreport, 11 1199-1202 (2000) [C1]
CitationsScopus - 4Web of Science - 3
2000Howe PRC, Nestel P, 'Dietary guidelines for a new millennium', Nutrition and Dietetics, 57 128-129 (2000) [C1]
2000Howe PRC, 'Why are we ignoring the dietary salt guideline?', Nutrition and Dietetics, 57 225-226 (2000) [C1]
2000Howe PRC, 'Fish - the missing guideline?', Nutridate, 11 5-7 (2000) [C1]
2000Howe PRC, Nestel PJ, 'Conference report: dietary guidelines for a new millenium', Food Australia, 52 211 (2000) [C3]
1999Ollis TE, Meyer BJ, Howe PRC, 'Australian food sources and intakes of omega-6 and omega-8 polyunsaturated fatty acids', ANNALS OF NUTRITION AND METABOLISM, 43 346-355 (1999)
DOI10.1159/000012803Author URL
CitationsScopus - 50Web of Science - 41
1999Howe P, 'Smart foods centre formed', FOOD AUSTRALIA, 51 78-78 (1999)
Author URL
1999Meyer BJ, Tsivis E, Howe PRC, Tapsell L, Calvert GD, 'Polyunsaturated fatty acid content of foods: differentiating between long and short chain omega-3 fatty acids', FOOD AUSTRALIA, 51 81-95 (1999)
Author URL
CitationsWeb of Science - 7
1999Sinclair AJ, Howe PRC, 'Recommended intakes of polyunsaturated fatty acids', FOOD AUSTRALIA, 51 524-524 (1999)
Author URL
1999Howe P, Phillips P, Saini R, Kassler-Taub K, 'The antihypertensive efficacy of the combination of irbesartan and hydrochlorothiazide assessed by 24-hour ambulatory blood pressure monitoring', CLINICAL AND EXPERIMENTAL HYPERTENSION, 21 1373-1396 (1999)
DOI10.3109/10641969909070855Author URL
CitationsScopus - 26Web of Science - 22
1996McLennan P, Howe P, Abeywardena M, Muggli R, Raederstorff D, Mano M, et al., 'The cardiovascular protective role of docosahexaenoic acid', EUROPEAN JOURNAL OF PHARMACOLOGY, 300 83-89 (1996)
DOI10.1016/0014-2999(95)00861-6Author URL
CitationsScopus - 153Web of Science - 150
1996Hobbs LM, Rayner TE, Howe PRC, 'Dietary fish oil prevents the development of renal damage in salt-loaded stroke-prone spontaneously hypertensive rats', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 23 508-513 (1996)
DOI10.1111/j.1440-1681.1996.tb02770.xAuthor URL
CitationsScopus - 12Web of Science - 13
1996Howe PRC, 'Fish oil supplements and hypertension', ISSFAL Newsletter, 3 2-5 (1996) [C3]
1995SUZUKAWA M, ABBEY M, HOWE PRC, NESTEL PJ, 'EFFECTS OF FISH-OIL FATTY-ACIDS ON LOW-DENSITY-LIPOPROTEIN SIZE, OXIDIZABILITY, AND UPTAKE BY MACROPHAGES', JOURNAL OF LIPID RESEARCH, 36 473-484 (1995)
Author URL
CitationsScopus - 148Web of Science - 131
1995JABLONSKIS LT, HOWE PRC, 'PLASMA ADRENALINE RESPONSES TO LONG-TERM MODIFICATION OF BLOOD-PRESSURE IN NORMOTENSIVE RATS AND HYPERTENSIVE RATS', JOURNAL OF HYPERTENSION, 13 319-325 (1995)
Author URL
CitationsScopus - 5Web of Science - 5
1995RAYNER TE, HOWE PRC, 'PURIFIED OMEGA-3-FATTY-ACIDS RETARD THE DEVELOPMENT OF PROTEINURIA IN SALT-LOADED HYPERTENSIVE RATS', JOURNAL OF HYPERTENSION, 13 771-780 (1995)
Author URL
CitationsScopus - 18Web of Science - 19
1994LUNGERSHAUSEN YK, ABBEY M, NESTEL PJ, HOWE PRC, 'REDUCTION OF BLOOD-PRESSURE AND PLASMA TRIGLYCERIDES BY OMEGA-3-FATTY-ACIDS IN TREATED HYPERTENSIVES', JOURNAL OF HYPERTENSION, 12 1041-1045 (1994)
Author URL
CitationsScopus - 49Web of Science - 43
1994Mcmurchie EJ, Burnard SL, Patten GS, King RA, Howe PRC, Head RJ, 'Depressed cheek cell sodium transport in human hypertension', Blood Pressure, 3 328-335 (1994)

Na+ transport activity was measured in cheek cells from untreated hypertensive subjects and age-matched normotensive controls identified from a blood pressure screening program. C... [more]

Na+ transport activity was measured in cheek cells from untreated hypertensive subjects and age-matched normotensive controls identified from a blood pressure screening program. Cheek cells were isolated by a simple mouth wash procedure and Na+ transport activity was measured as the proton-dependent uptake of 22Na+ using a rapid filtration assay. The rate of Na+ uptake was about 45% lower in hypertensive subjects and this difference persisted in a follow up study 2 years later involving those subjects who remained untreated for their hypertension. The proton independent Na+ uptake was also reduced by about 46% in the hypertensive group. The increase in the rate of cheek cell Na+ transport with increasing transcellular proton gradient values was also significantly lower in hypertensive subjects. The reduced cheek cell Na+ transport observed in hypertensive subjects may indicate decreased activity of the Na+/H+ antiporter and/or changes in the ion permeability properties of the cheek cell plasma membrane in the hypertensive state. This novel assay provides a biochemically based method for discriminating between normotensive and hypertensive subjects and makes use of tissue which can be obtained in a relatively non-invasive manner. © 1994 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

DOI10.3109/08037059409102282
CitationsScopus - 2
1994Jablonskis LT, Howe PRC, 'Elevated plasma adrenaline in spontaneously hypertensive rats', Blood Pressure, 3 106-111 (1994)

Having found that circulating adrenaline (AD) is selectively elevated in stroke-prone spontaneously hypertensive rats (SHRSP) compared with Wistar-Kyoto rats (WKY), we extended th... [more]

Having found that circulating adrenaline (AD) is selectively elevated in stroke-prone spontaneously hypertensive rats (SHRSP) compared with Wistar-Kyoto rats (WKY), we extended the comparison to include other normotensive and hypertensive rat strains. Aortic catheters were implanted in young (5-7 weeks) and old (7-9 months) WKY, Black-Hooded Wistar (BHW), Sprague Dawley (SD), spontaneously hypertensive rats (SHR) and SHRSP for repeated measurement of mean arterial pressure (MAP) and blood sampling under conscious resting conditions. In the young SHR and SHRSP, MAP was already significantly higher than in age-matched WKY but MAP in the SD rats was similar. Plasma AD was significantly higher in SHR and lower in SD rats when compared with WKY. There was no difference in plasma noradrenaline (NA) between strains at this age. At the older age, MAP was 40-60 mmHg higher in SHR and SHRSP than in WKY and BHW but was significantly lower in the SD strain. Circulating AD did not differ between the normotensive strains but was 3-4 times higher in the hypertensive strains. Plasma NA was elevated in SHR only. The acute reduction of MAP caused by ganglion blockade (an index of the sympathetically mediated component of resting blood pressure) was greater in SHR and SHRSP than in WKY at the older age only. However, the residual MAP after ganglion blockade was significantly higher in the hypertensive strains at both ages. Regression analysis showed that in the older rats, plasma AD was correlated with resting MAP, the reduction in MAP with ganglion blockade, the residual MAP and plasma NA. In the young rats, however, plasma AD levels were not correlated with either plasma NA or resting MAP. Thus, even though plasma AD is elevated in the hypertensive strains at an early age, it is not clear whether this increase contributes to the pathogenesis of hypertension. © 1994 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

DOI10.3109/08037059409101529
CitationsScopus - 8
1994Bexis S, Lungershausen YK, Mano MT, Howe PRC, Kong J-Q, Birkle DL, et al., 'Dietary fish oil administration retards blood pressure development and influences vascular properties in the spontaneously hypertensive rat (SHR) but not in the stroke prone-spontaneously hypertensive rat (SHR-SP)', Blood Pressure, 3 120-126 (1994)

In the present study, we compared the blood pressure in the SHR-SP and in the spontaneously hypertensive rat (SHR) after dietary administration of fish oil from 4 to 17 weeks of a... [more]

In the present study, we compared the blood pressure in the SHR-SP and in the spontaneously hypertensive rat (SHR) after dietary administration of fish oil from 4 to 17 weeks of age. The retarding influence of dietary fish oils on the development of hypertension was prominent in the SHR (26 mmHg) and not evident in the SHR-SP (8 mmHg). The enhanced development of blood pressure in both the SHR and the SHR-SP is characterised by an elevated maximum contraction in the mesenteric vascular bed to sympathetic nerve stimulation and to injected noradrenaline. In SHR, but not SHR-SP, this maximum contraction was significantly attenuated by dietary fish oil. Likewise, acetylcholine mediated relaxation of the isolated aorta was enhanced in preparations from the SHR but not the SHR-SP. These physiological changes were also associated with a change in the total n-3 polyunsaturated fatty acids (PUFAs) content in vascular tissue, which were inversely proportional to the prevailing blood pressure values seen in all three strains of rat receiving dietary fish oils. Platelet activated thromboxane production was equally depressed in WKY (Wistar Kyoto), SHR and SHR-SP rats. The results indicate that the blood pressure lowering effect of fish oil when administered during the period of development of hypertension is much greater in the SHR than it is in the SHR-SP. Furthermore the lowering of blood pressure by fish oil administration is related to a restoration of normal vascular contraction and normal vascular relaxation, but not related to a suppression of serum thromboxane production. © 1994 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

DOI10.3109/08037059409101531
CitationsScopus - 12
1994Jablonskis LT, Howe PRC, 'Lack of influence of circulating adrenaline on blood pressure in normotensive and hypertensive rats', Blood Pressure, 3 112-119 (1994)

The relationship between circulating adrenaline and blood pressure was examined by manipulating plasma adrenaline levels in both normotensive and hypertensive rats: bilateral adre... [more]

The relationship between circulating adrenaline and blood pressure was examined by manipulating plasma adrenaline levels in both normotensive and hypertensive rats: bilateral adrenalmedullectomy was performed in spontaneously hypertensive rats and stroke-prone spontaneously hypertensive rats; adrenaline bitartrate was infused chronically (25-32 µg/kg/h s.c.) into Wistar Kyoto, Sprague Dawley and stroke-prone rats via osmotic minipumps. Arterial and venous catheters were subsequently implanted for direct measurement of mean arterial pressure, blood sampling and drug administration in conscious rats. Adrenaline infusion for 5-6 weeks in Wistar Kyoto rats did not affect resting blood pressure (118 ± 3 versus 119 ± 1 mmHg in controls) even though plasma adrenaline was elevated 12-fold. Plasma noradrenaline was marginally elevated. Blood pressure was also unaffected by adrenaline infusion in Sprague Dawley or stroke-prone hypertensive rats. One week after adrenal medullectomy, plasma adrenaline was reduced 89% in spontaneously hypertensive rats, but blood pressure was unaffected. Ten weeks after adrenal medullectomy in young stroke-prone rats, resting blood pressure was slightly higher (167 ± 2 mmHg) than in control rats (157 ± 2 mmHg), although adrenaline was reduced by 34% in plasma and 67% in adrenal glands. Nitroprusside was infused acutely to lower blood pressure and reflexly elevate plasma noradrenaline. Neither of these responses were affected by chronic adrenaline infusion or adrenal medullectomy. In both adrenaline-infused Wistar Kyoto and medullectomised stroke-prone rats, autonomic blockade reduced blood pressure to a similar extent as in controls, indicating that the degree of sympathetic vasoconstriction was not altered by either treatment. Moreover, pressor responses to i.v. phenylephrine were similar in all groups, indicating that changes in plasma adrenaline did not affect post-synaptic receptor sensitivity. We conclude that elevated plasma adrenaline seen in spontaneous hypertensive rats is unlikely to contribute to their hypertension. © 1994 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

DOI10.3109/08037059409101530
CitationsScopus - 5
1994LUNGERSHAUSEN YK, HOWE PRC, 'IMPROVED DETECTION OF A BLOOD-PRESSURE RESPONSE TO DIETARY INTERVENTION WITH 24-HOUR AMBULATORY MONITORING', AMERICAN JOURNAL OF HYPERTENSION, 7 1115-1117 (1994)
Author URL
CitationsScopus - 11Web of Science - 9
1994HOWE PRC, LUNGERSHAUSEN YK, COBIAC L, DANDY G, NESTEL PJ, 'EFFECT OF SODIUM RESTRICTION AND FISH-OIL SUPPLEMENTATION ON BP AND THROMBOTIC RISK-FACTORS IN PATIENTS TREATED WITH ACE-INHIBITORS', JOURNAL OF HUMAN HYPERTENSION, 8 43-49 (1994)
Author URL
CitationsScopus - 13Web of Science - 17
1994MCMURCHIE EJ, BURNARD SL, PATTEN GS, SMITH RM, HEAD RJ, HOWE PRC, 'SODIUM-TRANSPORT ACTIVITY IN CHEEK EPITHELIAL-CELLS FROM ADOLESCENTS AT INCREASED RISK OF HYPERTENSION', JOURNAL OF HUMAN HYPERTENSION, 8 329-336 (1994)
Author URL
CitationsScopus - 2Web of Science - 5
1993NESTEL PJ, CLIFTON PM, HOWE PR, 'ENHANCED BLOOD-PRESSURE RESPONSE TO DIETARY SALT-GENDER DIFFERENCE AND EFFECT OF WAIST-HIP RATIO (WHR)', CIRCULATION, 88 455-455 (1993)
Author URL
1993NESTEL PJ, CLIFTON PM, NOAKES M, MCARTHUR R, HOWE PR, 'ENHANCED BLOOD-PRESSURE RESPONSE TO DIETARY SALT IN ELDERLY WOMEN, ESPECIALLY THOSE WITH SMALL WAIST-HIP RATIO', JOURNAL OF HYPERTENSION, 11 1387-1394 (1993)
DOI10.1097/00004872-199312000-00011Author URL
CitationsScopus - 39Web of Science - 36
1993JABLONSKIS LT, HOWE PRC, 'VASOPRESSIN COMPENSATES FOR ACUTE LOSS OF SYMPATHETIC PRESSOR TONE IN SPONTANEOUSLY HYPERTENSIVE RATS', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 20 380-383 (1993)
DOI10.1111/j.1440-1681.1993.tb01711.xAuthor URL
CitationsScopus - 4Web of Science - 6
1993MARLEY AM, ROGERS PF, LUNGERSHAUSEN YK, HOWE PRC, 'COMBINED EFFECTS OF DIETARY FISH OIL AND SODIUM RESTRICTION ON BLOOD-PRESSURE IN ENALAPRIL-TREATED HYPERTENSIVE RATS', AMERICAN JOURNAL OF HYPERTENSION, 6 121-126 (1993)
Author URL
CitationsScopus - 3Web of Science - 5
1992McMurchie E, Patten GS, Bumard SL, Smith RM, Howe PRC, 'Human cheek cell Na+/H+ antiporter activity in essential hypertension: Use as a novel predictive test', Journal of Molecular and Cellular Cardiology, 24 93112-93116 (1992) [C1]
DOI10.1016/0022-2828(92)93116-2
1992JABLONSKIS LT, ROGERS PF, LUNGERSHAUSEN YK, HOWE PRC, 'CHRONIC CENTRAL ADMINISTRATION OF ENALAPRILAT LOWERS BLOOD-PRESSURE IN STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS', JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 39 119-126 (1992)
DOI10.1016/0165-1838(92)90052-IAuthor URL
CitationsScopus - 6Web of Science - 8
1992COBIAC L, NESTEL PJ, WING LMH, HOWE PRC, 'A LOW-SODIUM DIET SUPPLEMENTED WITH FISH OIL LOWERS BLOOD-PRESSURE IN THE ELDERLY', JOURNAL OF HYPERTENSION, 10 87-92 (1992)
DOI10.1097/00004872-199201000-00014Author URL
CitationsScopus - 28Web of Science - 44
1992Howe PRC, Nestel PJ, 'Antihypertensive effects of fish oil combined with a low sodium diet', Heartbeat, 3 3-4 (1992) [C3]
1991ROGERS PF, HEAD GA, LUNGERSHAUSEN YK, HOWE PRC, 'EFFECTS OF DEPLETING CENTRAL AND PERIPHERAL ADRENALINE STORES ON BLOOD-PRESSURE IN STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS', JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 34 9-16 (1991)
DOI10.1016/0165-1838(91)90004-MAuthor URL
CitationsScopus - 3Web of Science - 4
1991HOWE PRC, COBIAC L, SMITH RM, 'LACK OF EFFECT OF SHORT-TERM CHANGES IN SODIUM-INTAKE ON BLOOD-PRESSURE IN ADOLESCENT SCHOOLCHILDREN', JOURNAL OF HYPERTENSION, 9 181-186 (1991)
DOI10.1097/00004872-199102000-00014Author URL
CitationsScopus - 27Web of Science - 23
1991HOWE PRC, LUNGERSHAUSEN YK, ROGERS PF, GERKENS JF, HEAD RJ, SMITH RM, 'EFFECTS OF DIETARY-SODIUM AND FISH OIL ON BLOOD-PRESSURE DEVELOPMENT IN STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS', JOURNAL OF HYPERTENSION, 9 639-644 (1991)
DOI10.1097/00004872-199107000-00009Author URL
CitationsScopus - 19Web of Science - 22
1990HOWE PRC, ROGERS PF, LUNGERSHAUSEN Y, 'EARLY INCREASE OF PRESSOR SENSITIVITY TO VASOCONSTRICTORS IN STROKE-PRONE HYPERTENSIVE RATS', EUROPEAN JOURNAL OF PHARMACOLOGY, 183 838-839 (1990)
DOI10.1016/0014-2999(90)92657-5Author URL
CitationsWeb of Science - 2
1990HOWE PRC, ROGERS PF, MINSON JB, 'DIETARY-SODIUM LOADING ELEVATES BLOOD-PRESSURE IN BARORECEPTOR DENERVATED RATS', JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 29 151-156 (1990)
DOI10.1016/0165-1838(90)90180-QAuthor URL
CitationsScopus - 9Web of Science - 9
1990HALLIDAY GM, LI YW, BLUMBERGS PC, JOH TH, COTTON RGH, HOWE PRC, et al., 'NEUROPATHOLOGY OF IMMUNOHISTOCHEMICALLY IDENTIFIED BRAIN-STEM NEURONS IN PARKINSONS-DISEASE', ANNALS OF NEUROLOGY, 27 373-385 (1990)
DOI10.1002/ana.410270405Author URL
CitationsScopus - 209Web of Science - 212
1989Chalmers JP, Doyle AE, Hopper JL, Howe PRC, Matthews PG, Mathews J, et al., 'Fall in blood pressure with modest reduction in dietary salt intake in mild hypertension', Lancet, 1 399-402 (1989)
CitationsScopus - 55Web of Science - 33
1989WAN DCC, SCANLON D, CHOI CL, BUNN SJ, HOWE PRC, LIVETT BG, 'CO-LOCALIZATION OF RNAS CODING FOR PHENYLETHANOLAMINE N-METHYLTRANSFERASE AND PROENKEPHALIN-A IN BOVINE AND OVINE ADRENALS', JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 26 231-240 (1989)
DOI10.1016/0165-1838(89)90172-0Author URL
CitationsScopus - 17Web of Science - 16
1989HOWE PRC, ROGERS PF, SMITH RM, 'ANTIHYPERTENSIVE EFFECT OF ALCOHOL IN SPONTANEOUSLY HYPERTENSIVE RATS', HYPERTENSION, 13 607-611 (1989)
Author URL
CitationsScopus - 15Web of Science - 12
1989SCHOBER M, HOWE PRC, SPERK G, FISCHERCOLBRIE R, WINKLER H, 'AN INCREASED POOL OF SECRETORY HORMONES AND PEPTIDES IN ADRENAL-MEDULLA OF STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS', HYPERTENSION, 13 469-474 (1989)
Author URL
CitationsScopus - 36Web of Science - 43
1989HOWE PRC, ROGERS PF, HEAD GA, 'LIMITED BAROREFLEX CONTROL OF HEART-RATE IN YOUNG STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS', JOURNAL OF HYPERTENSION, 7 69-75 (1989)
DOI10.1097/00004872-198901000-00011Author URL
CitationsScopus - 13Web of Science - 19
1989HOWE PRC, ROGERS PF, SMITH RM, 'EFFECTS OF CHRONIC ALCOHOL-CONSUMPTION AND ALCOHOL WITHDRAWAL ON BLOOD-PRESSURE IN STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS', JOURNAL OF HYPERTENSION, 7 387-393 (1989)
DOI10.1097/00004872-198905000-00007Author URL
CitationsScopus - 16Web of Science - 18
1989Chalmers JP, Doyle AE, Hopper JL, Howe PRC, Matthews PG, Mathews J, et al., 'Effects of replacing sodium intake in subjects on a low sodium diet: A crossover study', Clinical and Experimental Hypertension, A11 1011-1024 (1989)

Eighty-eight untreated subjects (mean age 58.6 ± 1.1 years; 73 males and 15 females) with diastolic blood pressure between 90 and 100 mmHg were recruited to the study. Subjects w... [more]

Eighty-eight untreated subjects (mean age 58.6 ± 1.1 years; 73 males and 15 females) with diastolic blood pressure between 90 and 100 mmHg were recruited to the study. Subjects were seen fortnightly and after four pre-diet visits were randomised into a normal sodium intake group (44 subjects receiving > 80 mmol sodium daily in the diet plus 80 mmol of sodium supplement as eight slow release sodium chloride tablets daily) or a low sodium intake group (44 subjects receiving < 80 mmol sodium daily in the diet plus eight slow release sodium chloride placebo tablets daily). Eight weeks later, subjects crossed over to the alternate tablets while continuing with the reduced sodium diet for another period o f 8 weeks. The difference in urine sodium between the low sodium phase and the normal sodium phase was 67 2 4 mmol/day independent of the order in which the treatments were given: the corresponding difference in urine potassium excretion was 1.2 5 1.4 mmol/day and was not significant. The differences in systolic and diastolic blood pressures between the low sodium and normal sodium phases for all 88 subjects were 3.6 ± 0.7 mmHg (95% confidence intervals 2.2-5.0) and 2.1 ± 0.4 mmHg (95% confidence intervals 1.3-2.9) respectively, and were independent of the order in which treatments were given (p < 0.005). On the other hand, comparison of the blood pressures of the two cohorts of subjects as parallel groups during the first test phase revealed that the falls in pressure were greater by 5.3 ± 1.4 (95% confidence intervals 2.7-8.1) mmHg (systolic) and 3.4 ± 0.8 (95% confidence intervals 1.8-5.0) mmHg (diastolic) in subjects with low sodium intake compared with those with normal sodium intake. These differences in blood pressure reduction obtained by analysis of the crossover study and of the parallel group study were not significant, with clear overlap of the 95% confidence intervals. Moderate dietary salt restriction causes reductions in blood pressure and around 3.5-5.5 mmHg (systolic) and 2-3.5 mmHg (diastolic) of these falls can be attributed specifically to reduction o f sodium chloride intake. © 1989 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

DOI10.3109/10641968909035388
CitationsScopus - 18
1988HALLIDAY GM, LI YW, JOH TH, COTTON RGH, HOWE PRC, GEFFEN LB, BLESSING WW, 'DISTRIBUTION OF MONOAMINE-SYNTHESIZING NEURONS IN THE HUMAN MEDULLA-OBLONGATA', JOURNAL OF COMPARATIVE NEUROLOGY, 273 301-317 (1988)
DOI10.1002/cne.902730303Author URL
CitationsScopus - 68Web of Science - 77
1988McMillen IC, Mulvogue HM, Coulter CL, Browne CA, Howe PRC, 'Ontogeny of catecholamine-synthesizing enzymes and enkephalins in the sheep adrenal medulla: An immunocytochemical study', Journal of Endocrinology, 118 221-226 (1988) [C1]
CitationsScopus - 21Web of Science - 38
Co-authorsCaroline Mcmillen
1988HOWE PRC, HEAD GA, ROGERS PF, 'PRESSOR RESPONSIVENESS OF THE SUB-RETROFACIAL NUCLEUS AND THE MIDBRAIN RETICULAR-FORMATION IN THE RAT AFTER 6-HYDROXYDOPAMINE-INDUCED LESIONS OF ASCENDING AND DESCENDING CATECHOLAMINE PATHWAYS', JOURNAL OF HYPERTENSION, 6 443-450 (1988)
DOI10.1097/00004872-198806000-00003Author URL
CitationsScopus - 6Web of Science - 5
1988ANDERSON CR, HOWE PRC, 'IS PHENYLETHANOLAMINE-N-METHYLTRANSFERASE (PNMT) CONTAINED IN RAT HYPOTHALAMIC NEURONS', NEUROSCIENCE LETTERS, 93 164-169 (1988)
DOI10.1016/0304-3940(88)90075-4Author URL
CitationsScopus - 7Web of Science - 15
1988HALLIDAY GM, LI YW, OLIVER J, JOH TH, COTTON RGH, HOWE PRC, et al., 'THE DISTRIBUTION OF NEUROPEPTIDE-Y-LIKE IMMUNOREACTIVE NEURONS IN THE HUMAN MEDULLA-OBLONGATA', NEUROSCIENCE, 26 179-191 (1988)
DOI10.1016/0306-4522(88)90136-4Author URL
CitationsScopus - 36Web of Science - 37
1988HALLIDAY GM, LI YW, JOH TH, COTTON RGH, HOWE PRC, GEFFEN LB, BLESSING WW, 'DISTRIBUTION OF SUBSTANCE P-LIKE IMMUNOREACTIVE NEURONS IN THE HUMAN MEDULLA-OBLONGATA - CO-LOCALIZATION WITH MONOAMINE-SYNTHESIZING NEURONS', SYNAPSE, 2 353-370 (1988)
DOI10.1002/syn.890020403Author URL
CitationsScopus - 37Web of Science - 37
1987LEVIN MC, SAWCHENKO PE, HOWE PRC, BLOOM S, POLAK JM, 'ORGANIZATION OF GALANIN-IMMUNOREACTIVE INPUTS TO THE PARAVENTRICULAR NUCLEUS WITH SPECIAL REFERENCE TO THEIR RELATIONSHIP TO CATECHOLAMINERGIC AFFERENTS', JOURNAL OF COMPARATIVE NEUROLOGY, 261 562-582 (1987)
DOI10.1002/cne.902610408Author URL
CitationsScopus - 106Web of Science - 161
1987HEAD GA, HOWE PRC, 'EFFECTS OF 6-HYDROXYDOPAMINE AND THE PNMT INHIBITOR LY134046 ON PRESSOR-RESPONSES TO STIMULATION OF THE SUBRETROFACIAL NUCLEUS IN ANESTHETIZED STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS', JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 18 213-224 (1987)
DOI10.1016/0165-1838(87)90120-2Author URL
CitationsScopus - 10Web of Science - 13
1987CROFTS JN, HOWE PRC, 'LIMITED DEPLETION OF CENTRAL ADRENALINE STORES FOLLOWING ADMINISTRATION OF ADRENALINE SYNTHESIS INHIBITORS IN RATS', NEUROCHEMISTRY INTERNATIONAL, 10 347-353 (1987)
DOI10.1016/0197-0186(87)90109-4Author URL
CitationsScopus - 1Web of Science - 1
1986RATTIGAN S, HOWE PRC, CLARK MG, 'THE EFFECT OF A HIGH-FAT DIET AND SUCROSE DRINKING OPTION ON THE DEVELOPMENT OF OBESITY IN SPONTANEOUSLY HYPERTENSIVE RATS', BRITISH JOURNAL OF NUTRITION, 56 73-80 (1986)
DOI10.1079/BJN19860086Author URL
CitationsScopus - 8Web of Science - 9
1986BLESSING WW, HOWE PRC, JOH TH, OLIVER J, WILLOUGHBY JO, 'DISTRIBUTION OF TYROSINE-HYDROXYLASE AND NEUROPEPTIDE Y-LIKE IMMUNOREACTIVE NEURONS IN RABBIT MEDULLA-OBLONGATA, WITH ATTENTION TO COLOCALIZATION STUDIES, PRESUMPTIVE ADRENALINE-SYNTHESIZING PERIKARYA, AND VAGAL PREGANGLIONIC CELLS', JOURNAL OF COMPARATIVE NEUROLOGY, 248 285-300 (1986)
DOI10.1002/cne.902480211Author URL
CitationsScopus - 118Web of Science - 190
1986HOWE PRC, ROGERS PF, MORRIS MJ, CHALMERS JP, SMITH RM, 'PLASMA-CATECHOLAMINES AND NEUROPEPTIDE-Y AS INDEXES OF SYMPATHETIC-NERVE ACTIVITY IN NORMOTENSIVE AND STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS', JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 8 1113-1121 (1986)
DOI10.1097/00005344-198611000-00004Author URL
CitationsScopus - 33Web of Science - 69
1986PILOWSKY P, MINSON J, HODGSON A, HOWE P, CHALMERS J, 'DOES SUBSTANCE-P COEXIST WITH ADRENALINE IN NEURONS OF THE ROSTRAL VENTROLATERAL MEDULLA IN THE RAT', NEUROSCIENCE LETTERS, 71 293-298 (1986)
DOI10.1016/0304-3940(86)90636-1Author URL
CitationsScopus - 30Web of Science - 46
1986HOWE PRC, ROGERS PF, SMITH RM, JUREIDINI KF, 'EFFECTS OF SHORT-TERM MODIFICATION OF DIETARY-SODIUM INTAKE ON PLASMA-CATECHOLAMINES AND BLOOD-PRESSURE IN PREHYPERTENSIVE CHILDREN', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 13 305-309 (1986)
DOI10.1111/j.1440-1681.1986.tb00353.xAuthor URL
CitationsScopus - 1Web of Science - 1
1985SAWCHENKO PE, SWANSON LW, GRZANNA R, HOWE PRC, BLOOM S, POLAK JM, 'COLOCALIZATION OF NEUROPEPTIDE-Y IMMUNOREACTIVITY IN BRAIN-STEM CATECHOLAMINERGIC NEURONS THAT PROJECT TO THE PARAVENTRICULAR NUCLEUS OF THE HYPOTHALAMUS', JOURNAL OF COMPARATIVE NEUROLOGY, 241 138-153 (1985)
DOI10.1002/cne.902410203Author URL
CitationsWeb of Science - 603
1985HOWE PRC, 'BLOOD-PRESSURE CONTROL BY NEUROTRANSMITTERS IN THE MEDULLA-OBLONGATA AND SPINAL-CORD', JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 12 95-115 (1985)
DOI10.1016/0165-1838(85)90054-2Author URL
CitationsScopus - 25Web of Science - 45
1985HOWE PR, ROGERS PF, MINSON JB, 'INFLUENCE OF DIETARY-SODIUM ON BLOOD-PRESSURE IN BARORECEPTOR-DENERVATED RATS', JOURNAL OF HYPERTENSION, 3 457-460 (1985)
Author URL
CitationsScopus - 27Web of Science - 30
1985HOWE PRC, ROGERS PF, SMITH RM, 'RETARDED DEVELOPMENT OF HYPERTENSION IN STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS FOLLOWING CHRONIC ALCOHOL-CONSUMPTION', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 12 273-277 (1985)
DOI10.1111/j.1440-1681.1985.tb02646.xAuthor URL
CitationsScopus - 3Web of Science - 10
1985Howe PRC, Jureidini KF, Smith RM, 'Sodium and blood pressure in children: a short term dietary intervention study', Proceedings of the Nutrition Society Australia, 10 121-124 (1985) [C3]
1984SMITH RM, HOWE PRC, OLIVER J, WILLOUGHBY JO, 'GROWTH-HORMONE RELEASING-FACTOR IMMUNOREACTIVITY IN RAT HYPOTHALAMUS', NEUROPEPTIDES, 4 109-115 (1984)
DOI10.1016/0143-4179(84)90121-5Author URL
CitationsScopus - 25Web of Science - 52
1984HOWE PRC, ROGERS PF, BLESSING WW, 'VISUALIZATION OF CATECHOLAMINE-FLUORESCENT NERVE-CELL BODIES IN THE RAT-BRAIN AFTER COLCHICINE TREATMENT', NEUROSCIENCE LETTERS, 52 287-292 (1984)
DOI10.1016/0304-3940(84)90176-9Author URL
CitationsScopus - 4Web of Science - 10
1984GOODCHILD AK, MOON EA, DAMPNEY RAL, HOWE PRC, 'EVIDENCE THAT ADRENALINE NEURONS IN THE ROSTRAL VENTROLATERAL MEDULLA HAVE A VASOPRESSOR FUNCTION', NEUROSCIENCE LETTERS, 45 267-272 (1984)
DOI10.1016/0304-3940(84)90237-4Author URL
CitationsScopus - 52Web of Science - 84
1984CHALMERS JP, MINSON J, DENOROY L, STEAD B, HOWE PRC, 'BRAIN-STEM PNMT NEURONS AND EXPERIMENTAL-HYPERTENSION IN THE RAT', CLINICAL AND EXPERIMENTAL HYPERTENSION PART A-THEORY AND PRACTICE, 6 243-258 (1984)
DOI10.3109/10641968409062563Author URL
CitationsScopus - 7Web of Science - 13
1984Howe PRC, 'Influence of sodium on neural control of blood pressure in animal models', Proceedings of the Nutrition Society Australia, 9 27-34 (1984) [C3]
1983HOWE PRC, ROGERS PF, KING RA, SMITH RM, 'A BIOCHEMICAL AND IMMUNOHISTOCHEMICAL STUDY OF CENTRAL SEROTONIN NERVES IN RATS WITH CHRONIC THIAMINE-DEFICIENCY', BRAIN RESEARCH, 270 19-28 (1983)
DOI10.1016/0006-8993(83)90787-4Author URL
CitationsScopus - 3Web of Science - 5
1983HOWE PRC, KUHN DM, MINSON JB, STEAD BH, CHALMERS JP, 'EVIDENCE FOR A BULBOSPINAL SEROTONERGIC PRESSOR PATHWAY IN THE RAT-BRAIN', BRAIN RESEARCH, 270 29-36 (1983)
DOI10.1016/0006-8993(83)90788-6Author URL
CitationsScopus - 76Web of Science - 143
1983HOWE PRC, MOON E, DAMPNEY RAL, 'DISTRIBUTION OF SEROTONIN NERVE-CELLS IN THE RABBIT BRAIN-STEM', NEUROSCIENCE LETTERS, 38 125-130 (1983)
DOI10.1016/0304-3940(83)90028-9Author URL
CitationsScopus - 18Web of Science - 29
1983HOWE PRC, ROGERS PF, KING RA, SMITH RM, 'ELEVATION OF BLOOD-PRESSURE IN HYPERTENSIVE RATS AFTER LESIONING SEROTONIN NERVES IN THE DORSOMEDIAL MEDULLA-OBLONGATA', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 10 273-277 (1983)
DOI10.1111/j.1440-1681.1983.tb00196.xAuthor URL
CitationsScopus - 4Web of Science - 7
1982HOWE PRC, CUELLO AC, COSTA M, FURNESS JB, 'IMPROVED IMMUNOHISTOCHEMICAL VISUALIZATION OF CENTRAL SEROTONIN NERVES AFTER LOADING WITH 5,7-DIHYDROXYTRYPTAMINE', NEUROSCIENCE LETTERS, 29 1-6 (1982)
DOI10.1016/0304-3940(82)90354-8Author URL
CitationsScopus - 10Web of Science - 15
1982HOWE PRC, STEAD BH, LOVENBERG W, CHALMERS JP, 'EFFECTS OF CENTRAL SEROTONIN NERVE LESIONS ON BLOOD-PRESSURE IN NORMOTENSIVE AND HYPERTENSIVE RATS', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 9 335-339 (1982)
DOI10.1111/j.1440-1681.1982.tb00817.xAuthor URL
CitationsScopus - 6Web of Science - 14
1982LIVETT BG, DAY R, ELDE RP, HOWE PRC, 'CO-STORAGE OF ENKEPHALINS AND ADRENALINE IN THE BOVINE ADRENAL-MEDULLA', NEUROSCIENCE, 7 1323-1332 (1982)
DOI10.1016/0306-4522(82)91138-1Author URL
CitationsScopus - 83Web of Science - 157
1982Howe PRC, 'Visualisation of central 5 hyroxytryptamine nerves', Proceedings of the Australian Physiological and Pharmacological Society, 13 60-65 (1982) [C3]
1981HOWE PRC, LOVENBERG W, CHALMERS JP, 'INCREASED NUMBER OF PNMT-IMMUNOFLUORESCENT NERVE-CELL BODIES IN THE MEDULLA-OBLONGATA OF STROKE-PRONE HYPERTENSIVE RATS', BRAIN RESEARCH, 205 123-130 (1981)
DOI10.1016/0006-8993(81)90724-1Author URL
CitationsScopus - 14Web of Science - 40
1981HOWE PRC, WEST MJ, PROVIS JC, CHALMERS JP, 'CONTENT AND TURNOVER OF NORADRENALINE IN SPINAL-CORD AND CEREBELLUM OF SPONTANEOUSLY HYPERTENSIVE AND STROKE-PRONE RATS', EUROPEAN JOURNAL OF PHARMACOLOGY, 73 123-129 (1981)
DOI10.1016/0014-2999(81)90083-2Author URL
CitationsScopus - 12Web of Science - 25
1981BUNE AJ, CHALMERS JP, GRAHAM J, HOWE PRC, WEST MJ, WING LMH, 'DOUBLE-BLIND TRIAL COMPARING GUANFACINE AND METHYLDOPA IN PATIENTS WITH ESSENTIAL-HYPERTENSION', EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 19 309-315 (1981)
DOI10.1007/BF00544579Author URL
CitationsScopus - 1Web of Science - 13
1981CHALMERS JP, HOWE PRC, WALLMANN Y, TUMULS I, 'ADRENALINE NEURONS AND PNMT ACTIVITY IN THE BRAIN AND SPINAL-CORD OF GENETICALLY HYPERTENSIVE RATS AND RATS WITH DOCA-SALT HYPERTENSION', CLINICAL SCIENCE, 61 S219-S221 (1981)
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CitationsScopus - 1Web of Science - 5
1981HOWE PRC, WEST MJ, CHALMERS JP, 'ALTERED CARDIAC NORADRENALINE STORES IN DOCA-SALT HYPERTENSIVE RATS', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 8 83-87 (1981)
DOI10.1111/j.1440-1681.1981.tb00137.xAuthor URL
CitationsScopus - 2Web of Science - 3
1981HOWE PRC, PROVIS JC, FURNESS JB, COSTA M, CHALMERS JP, 'RESIDUAL CATECHOLAMINES IN EXTRINSICALLY DENERVATED GUINEA-PIG ILEUM', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 8 327-333 (1981)
DOI10.1111/j.1440-1681.1981.tb00736.xAuthor URL
CitationsScopus - 2Web of Science - 5
1981HOWE PRC, STEAD BH, CHALMERS JP, 'CENTRAL 5-HYDROXYTRYPTAMINE AND TRYPTOPHAN-HYDROXYLASE IN HYPERTENSIVE RATS', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 8 408-408 (1981)
Author URL
CitationsScopus - 4Web of Science - 5
1981CHALMERS JP, HOWE PRC, COSTA M, FURNESS J, LOVENBERG W, WALLMAN Y, 'ADRENALINE SYNTHESIZING NERVE-CELLS IN THE MEDULLA OF NORMOTENSIVE AND HYPERTENSIVE RATS', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 8 459-462 (1981)
DOI10.1111/j.1440-1681.1981.tb00749.xAuthor URL
CitationsScopus - 3Web of Science - 3
1981CHALMERS JP, BLESSING WW, WEST MJ, HOWE PRC, COSTA M, FURNESS JB, 'IMPORTANCE OF NEW CATECHOLAMINE PATHWAYS IN CONTROL OF BLOOD-PRESSURE', CLINICAL AND EXPERIMENTAL HYPERTENSION, 3 393-416 (1981)
DOI10.3109/10641968109033673Author URL
CitationsScopus - 13Web of Science - 27
1980Furness JB, Costa M, Howe PR, 'Intrinsic amine-handling neurons in the intestine.', Advances in biochemical psychopharmacology, 25 367-372 (1980)
CitationsScopus - 2
1980HOWE PRC, PROVIS JC, WEST MJ, CHALMERS JP, 'INCREASED NORADRENALINE (NA) CONCENTRATION IN CEREBELLUM AND SPINAL-CORD OF STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 7 63-63 (1980)
Author URL
1980HOWE PRC, COSTA M, FURNESS JB, CHALMERS JP, 'SIMULTANEOUS DEMONSTRATION OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE IMMUNOFLUORESCENT AND CATECHOLAMINE FLUORESCENT NERVE-CELL BODIES IN THE RAT MEDULLA-OBLONGATA', NEUROSCIENCE, 5 2229-2238 (1980)
DOI10.1016/0306-4522(80)90139-6Author URL
CitationsScopus - 106Web of Science - 184
1979HOWE PRC, PROVIS JC, WEST MJ, CHALMERS JP, 'CHANGES IN CARDIAC NOREPINEPHRINE IN SPONTANEOUSLY HYPERTENSIVE AND STROKE-PRONE RATS', JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1 115-122 (1979)
DOI10.1097/00005344-197901000-00011Author URL
CitationsScopus - 15Web of Science - 34
1979HOWE PRC, CHALMERS JP, MULLER J, PROVIS JC, WEST MJ, 'HISTAMINE LEVELS IN BRAIN, SPINAL-CORD AND HEART OF GENETICALLY HYPERTENSIVE RATS', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 6 216-217 (1979)
Author URL
1979Howe PRC, West MJ, Chalmers JP, Provis JC, 'Histamine and noradrenaline in the heart of genetic hypertensive rats', Japanese Heart Journal, 20 325-327 (1979) [C3]
1978BLESSING WW, CHALMERS JP, HOWE PRC, 'DISTRIBUTION OF CATECHOLAMINE-CONTAINING CELL BODIES IN RABBIT CENTRAL NERVOUS-SYSTEM', JOURNAL OF COMPARATIVE NEUROLOGY, 179 407-423 (1978)
DOI10.1002/cne.901790210Author URL
CitationsScopus - 77Web of Science - 140
1978MALTA E, HOWE PRC, LLOYD JC, CHALMERS JP, 'EFFECTS OF INTRA-VENTRICULAR INJECTIONS OF HISTAMINE ON ARTERIAL BLOOD-PRESSURE AND HEART-RATE IN CONSCIOUS RABBITS', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 5 277-277 (1978)
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1977HOWE PRC, TELFER JA, LIVETT BG, AUSTIN L, 'EXTRAJUNCTIONAL ACETYLCHOLINE RECEPTORS IN DYSTROPHIC MOUSE MUSCLES', EXPERIMENTAL NEUROLOGY, 56 42-51 (1977)
DOI10.1016/0014-4886(77)90137-6Author URL
CitationsScopus - 1Web of Science - 5
1977HOWE PRC, FENWICK EM, ROSTAS JAP, LIVETT BG, 'IMMUNOCHEMICAL COMPARISON OF SYNAPTIC PLASMA-MEMBRANE AND SYNAPTIC VESICLE MEMBRANE ANTIGENS', JOURNAL OF NEUROCYTOLOGY, 6 339-352 (1977)
DOI10.1007/BF01175195Author URL
CitationsScopus - 3Web of Science - 10
Co-authorsJohn Rostas
1976HOWE PRC, LIVETT BG, AUSTIN L, 'INCREASED BINDING OF ALPHA-BUNGAROTOXIN IN DYSTROPHIC MOUSE MUSCLE', EXPERIMENTAL NEUROLOGY, 51 132-140 (1976)
DOI10.1016/0014-4886(76)90058-3Author URL
CitationsScopus - 5Web of Science - 10
1976HOWE PRC, TELFER JA, AUSTIN L, 'BINDING-SITES FOR I-125-LABELED ALPHA-BUNGAROTOXIN IN NORMAL AND DENERVATED MOUSE MUSCLE', EXPERIMENTAL NEUROLOGY, 52 272-284 (1976)
DOI10.1016/0014-4886(76)90171-0Author URL
CitationsScopus - 9Web of Science - 11
1976FILLENZ M, HOWE PRC, WEST DP, 'VESICULAR NORADRENALINE IN NERVE-TERMINALS OF RAT-HEART FOLLOWING INHIBITION OF MONOAMINE-OXIDASE AND ADMINISTRATION OF NORADRENALINE', NEUROSCIENCE, 1 113-116 (1976)
DOI10.1016/0306-4522(76)90005-1Author URL
CitationsScopus - 10Web of Science - 15
1975FILLENZ M, HOWE PRC, 'DEPLETION OF NORADRENALINE STORES IN SYMPATHETIC-NERVE TERMINALS', JOURNAL OF NEUROCHEMISTRY, 24 683-688 (1975)
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CitationsScopus - 9Web of Science - 22
1975HOWE PRC, ROSTAS JAP, FENWICK EM, LIVETT BG, 'FURTHER EVIDENCE FOR INCORPORATION OF SYNAPTIC VESICLE PROTEINS INTO SYNAPTOSOMAL PLASMA-MEMBRANES', PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY, 8 95-95 (1975)
Author URL
CitationsWeb of Science - 1
Co-authorsJohn Rostas
1972CRIPPS H, HOWE PRC, DEARNALE D, 'ENHANCEMENT OF NORADRENALINE DEPLETION IN CAT SPLEEN BY PHENOXYBENZAMINE AND PHENTOLAMINE', BRITISH JOURNAL OF PHARMACOLOGY, 46 358-& (1972)
Author URL
CitationsWeb of Science - 7
1971Fillenz M, Howe PR, 'The contribution of small and large vesicles to noradrenaline release.', Journal of Physiology, 212 (1971)
CitationsScopus - 1
1971Fillenz M, Howe PR, 'Increase in the vesicular noradrenaline of nerve terminals.', Journal of Physiology, 217 (1971)
CitationsScopus - 4
1971Fillenz M, Howe PR, 'Life cycle of vesicles in sympathetic nerve terminals.', Journal of Physiology, 218 (1971)
CitationsScopus - 4
Show 219 more journal articles

Review (1 outputs)

YearCitationAltmetricsLink
2011Tsiros MD, Coates AM, Howe PRC, Grimshaw PN, Buckley JD, 'Obesity: The new childhood disability?', Obesity Reviews (2011) [D1]
DOI10.1111/j.1467-789X.2009.00706.x
CitationsScopus - 23Web of Science - 24

Conference (35 outputs)

YearCitationAltmetricsLink
2015Wong RHX, Jnasen L, Nealon R, Garg ML, Howe PRC, 'A PILOT INVESTIGATION OF CEREBROVASCULAR RESPONSIVENESS TO A NEUROPSYCHOLOGICAL TEST BATTERY IN ADULTS WITH TYPE 2 DIABETES MELLITUS', HYPERTENSION, Adelaide, AUSTRALIA (2015)
Author URL
2014Coates AM, Cai S, Burres L, Berry NM, Buckley JD, Beltrame J, et al., 'Relationship between erythrocyte content of long chain omega-3 polyunsaturated fatty acids and depression in patients with ischemic heart disease or heart failure.', Poster abstracts (ISSFAL) 2014 Congress, Stockholm, Sweden (2014) [E3]
2014Fan C, Georgiou KR, McKinnon RA, Keefe DM, Howe PR, Xian CJ, 'ADVERSE EFFECTS OF COMBINATION BREAST CANCER CHEMOTHERAPY ON BONE AND BONE MARROW', OSTEOPOROSIS INTERNATIONAL, Taipei, TAIWAN (2014) [E3]
Author URL
2014Howe PRC, 'Circulatory effects of bioactive nutrients deliver cardio-metabolic and cognitive benefits', Nutrients, Phuket, Thailand (2014) [E3]
2014Barbour J, Howe PRC, Buckley J, Bryan J, Coates A, 'Consuming Hi-oleic peanuts for 12 weeks can increase energy intake without change in body composition', Book of abstracts, Adelaide (2014) [E3]
2013Coates A, Barbour J, Buckley J, Bryan J, Howe P, 'Hi-Oleic peanut preload lowers energy intake and energy density of a subsequent meal', FASEB JOURNAL, Boston, MA (2013) [E3]
Author URL
2013Barbour JA, Howe PRC, Buckley JD, Bryan J, Coates AM, 'Effect of peanut consumption on satiety and energy intake', FASEB JOURNAL, Boston, MA (2013) [E3]
Author URL
2012Wong RHX, Berry NM, Buckley JD, Coates AM, Howe PRC, 'REGULAR CONSUMPTION OF A WILD GREEN OAT EXTRACT ENHANCES SYSTEMIC AND CEREBRAL VASODILATOR FUNCTION', HYPERTENSION, Perth, AUSTRALIA (2012) [E3]
Author URL
CitationsWeb of Science - 1
2012Coates A, Bartold M, Hughes T, Howe P, 'Fish oil supplementation as adjunct therapy for periodontitis', FASEB JOURNAL, San Diego, CA (2012) [E3]
Author URL
2009Davison K, Berry NM, Coates AM, Misan G, Buckley JD, Howe PRC, 'IS THERE A THRESHOLD EFFECT OF FLAVANOL RICH COCOA ON BLOOD PRESSURE?', HYPERTENSION, Melbourne, AUSTRALIA (2009) [E3]
Author URL
CitationsWeb of Science - 1
2009Howe P, Buckley J, 'DIETARY REQUIREMENTS FOR OMEGA-6 AND OMEGA-3 PUFAS - IS THE BALANCE RELEVANT?', ANNALS OF NUTRITION AND METABOLISM (2009) [E3]
Author URL
CitationsWeb of Science - 1
2009Head G, Mihailidou S, Duggan K, Beilin L, Berry N, Cowley D, et al., 'RELATIONSHIP BETWEEN AMBULATORY AND CLINIC BLOOD PRESSURE: A HIGH BLOOD PRESSURE RESEARCH COUNCIL OF AUSTRALIA INITIATIVE', JOURNAL OF HYPERTENSION, Milan, ITALY (2009) [E3]
Author URL
2009Thorp AA, Buckley JD, Coates AM, Mori TA, Hodgson J, Mansour J, et al., 'EFFECTS OF SOY PROTEIN AND ISOFLAVONE INTAKE ON ARTERIAL FUNCTION', JOURNAL OF HYPERTENSION, Milan, ITALY (2009) [E3]
Author URL
2008Solowij N, Grenyer B, Meyer B, Howe P, 'Increased suicide risk in depressed patients predicted by long-chain fatty acids', INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, Munich, GERMANY (2008) [E3]
Author URL
2008Coates A, Pettman T, Buckley J, Misan G, Howe P, 'Health Benefits of a Group Based Diet and Lifestyle Modification Program for Metabolic Syndrome', OBESITY, Phoenix, AZ (2008) [E3]
Author URL
2008Davison K, Coates AM, Buckley JD, Howe PRC, 'SELECTIVE EFFECTS OF COCOA FLAVANOLS AND EXERCISE ON CARDIO-METABOLIC RISK FACTORS IN OVERWEIGHT/OBESE SUBJECTS', HYPERTENSION, Adelaide, AUSTRALIA (2008) [E3]
Author URL
2008Berry N, Davison K, Buckley JD, Coates AM, Howe PRC, 'Flavanol-rich cocoa attenuates blood pressure responsiveness to exercise', JOURNAL OF HYPERTENSION, Berlin, GERMANY (2008) [E3]
Author URL
CitationsWeb of Science - 1
2005Saint DA, Murphy K, Howe P, Ninio D, 'Dietary fish oil protects against stretch-induced atrial fibrillation in a rabbit model', FASEB JOURNAL, San Diego, CA (2005)
Author URL
2004Elliott M, McLennan P, Howe P, 'Dietary modification of hypertension induced cardiac damage', JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, Brisbane, AUSTRALIA (2004)
Author URL
2004Howe PRC, Meyer BJ, 'Lipid-lowering effectiveness of soy protein diets - Is it defined by equol-producing status?', JOURNAL OF NUTRITION, Orlando, FL (2004)
Author URL
2003Ridges L, Martin G, Larkin T, Meyer B, Howe P, 'The effect of the combination of an omega-3 supplement together with soy isoflavone consumption on cardiovascular risk factors in combined hyperlipidaemic subjects', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, MELBOURNE, AUSTRALIA (2003)
Author URL
CitationsWeb of Science - 1
2002Howe PRC, 'Modifying foods to meet fatty acid requirements', Proceedings of International Conference on Essential Fatty Acids and Human Nutrition and Health, Shanghai (2002) [E3]
2002Howe PRC, 'Synergy between Omega-3 fatty acids and Cardiovascular Drugs', Proceedings of international workshop on omega-3 fatty acids & primary prevention of coronary heart disease, Montreal (2002) [E3]
1999Howe PRC, Clifton PM, James MJ, 'Equal antithrombotic and triglyceride-lowering effectiveness of eicosapentaenoic acid-rich and docosahexaenoic acid-rich fish oil supplements', LIPIDS, LYON, FRANCE (1999)
DOI10.1007/BF02562326Author URL
CitationsScopus - 14Web of Science - 11
1998Howe PRC, 'omega 3-enriched pork', RETURN OF OMEGA-3 FATTY ACIDS INTO THE FOOD SUPPLY, NIH, NATCHER CONF CTR, BETHESDA, MD (1998)
Author URL
CitationsScopus - 11Web of Science - 9
1998Howe PRC, 'omega 3 fatty acids - An Australian perspective', RETURN OF OMEGA-3 FATTY ACIDS INTO THE FOOD SUPPLY, NIH, NATCHER CONF CTR, BETHESDA, MD (1998)
Author URL
CitationsScopus - 2Web of Science - 2
1997Howe PRC, 'Dietary fats and hypertension - Focus on fish oil', LIPIDS AND SYNDROMES OF INSULIN RESISTANCE, SMOLENICE CASTLE, SLOVAKIA (1997)
DOI10.1111/j.1749-6632.1997.tb51846.xAuthor URL
CitationsScopus - 34Web of Science - 27
1997Lungershausen YK, Howe PRC, Clifton PM, Hughes CRT, Phillips P, Graham JJ, Thomas DW, 'Evaluation of an omega-3 fatty acid supplement in diabetics with microalbuminuria', LIPIDS AND SYNDROMES OF INSULIN RESISTANCE, SMOLENICE CASTLE, SLOVAKIA (1997)
DOI10.1111/j.1749-6632.1997.tb51848.xAuthor URL
CitationsScopus - 11Web of Science - 12
1996Howe PRC, Abbey M, Topping DL, Belling B, Illman R, 'Enrichment of pork with omega-3 fatty acids from fishmeal', PROCEEDINGS OF THE NUTRITION SOCIETY OF AUSTRALIA, VOL 20, SYDNEY, AUSTRALIA (1996)
Author URL
CitationsWeb of Science - 2
1995HOWE PRC, 'CAN WE RECOMMEND FISH-OIL FOR HYPERTENSION', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, PERTH, AUSTRALIA (1995)
DOI10.1111/j.1440-1681.1995.tb01980.xAuthor URL
CitationsScopus - 16Web of Science - 11
1993MCMURCHIE EJ, BURNARD SL, PATTEN GS, SMITH RM, HEAD RJ, HOWE PRC, 'HUMAN CHEEK EPITHELIAL-CELL SODIUM-TRANSPORT ACTIVITY IN ESSENTIAL-HYPERTENSION', JOURNAL OF HYPERTENSION, MILAN, ITALY (1993)
Author URL
CitationsScopus - 1Web of Science - 4
1991COBIAC L, NESTEL PJ, WING LMH, HOWE PRC, 'EFFECTS OF DIETARY-SODIUM RESTRICTION AND FISH OIL SUPPLEMENTS ON BLOOD-PRESSURE IN THE ELDERLY', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, MELBOURNE, AUSTRALIA (1991)
DOI10.1111/j.1440-1681.1991.tb01442.xAuthor URL
CitationsScopus - 9Web of Science - 15
1991HOWE PRC, ROGERS PF, LUNGERSHAUSEN Y, 'BLOOD-PRESSURE REDUCTION BY FISH OIL IN ADULT-RATS WITH ESTABLISHED HYPERTENSION - DEPENDENCE ON SODIUM-INTAKE', PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, ADELAIDE, AUSTRALIA (1991)
DOI10.1016/0952-3278(91)90193-9Author URL
CitationsScopus - 12Web of Science - 19
1991HEAD RJ, MANO MT, BEXIS S, HOWE PRC, SMITH RM, 'DIETARY FISH OIL ADMINISTRATION RETARDS THE DEVELOPMENT OF HYPERTENSION AND INFLUENCES VASCULAR NEUROEFFECTOR FUNCTION IN THE STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RAT (SHRSP)', PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, ADELAIDE, AUSTRALIA (1991)
DOI10.1016/0952-3278(91)90194-AAuthor URL
CitationsScopus - 20Web of Science - 25
1989HOWE PRC, HEAD RJ, SMITH RM, 'HIGH DIETARY-SODIUM INTAKE COUNTERACTS ANTIHYPERTENSIVE EFFECT OF FISH OIL IN SPONTANEOUSLY HYPERTENSIVE RATS', PROCEEDINGS OF THE NUTRITION SOCIETY OF AUSTRALIA, VOL 14, BRISBANE, AUSTRALIA (1989)
Author URL
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Grants and Funding

Summary

Number of grants57
Total funding$14,871,402

Click on a grant title below to expand the full details for that specific grant.


20151 grants / $35,000

Effects of long-chain Omega-3 polyunsaturated fatty acid (LCn-3PUFA) supplementation on cerebral circulation and cognitive function$35,000

Funding body: Westfund Health

Funding bodyWestfund Health
Project TeamProfessor Peter Howe, Doctor Rachel Wong
SchemeResearch Grant
RoleLead
Funding Start2015
Funding Finish2015
GNoG1500894
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

20144 grants / $143,860

Pork consumption and serum irisin levels in type 2 diabetes$50,300

Funding body: CRC for High Integrity Australian Pork

Funding bodyCRC for High Integrity Australian Pork
Project TeamProfessor Manohar Garg, Professor Peter Howe, Doctor Rachel Wong
SchemeInnovative Research
RoleInvestigator
Funding Start2014
Funding Finish2014
GNoG1400612
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

Dose response evaluation of resveratrol supplementation on cerebrovascular function, mood and cognitive performance in type 2 diabetes mellitus$45,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamProfessor Peter Howe, Doctor Rachel Wong, Professor Andrew Scholey
SchemeDementia Collaborative Research Centres (DCRC)
RoleLead
Funding Start2014
Funding Finish2014
GNoG1400899
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

Assisting post-menopausal women towards healthy ageing - can resveratrol enhance mood and counteract cognitive decline?$25,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamProfessor Peter Howe, Doctor Rachel Wong, Professor Andrew Scholey
SchemeProject Grant
RoleLead
Funding Start2014
Funding Finish2014
GNoG1401413
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Dose response evaluation of resveratrol supplementation on cerebrovascular function, mood and cognitive performance in type 2 diabetes mellitus$23,560

Funding body: DSM Nutritional Products AG

Funding bodyDSM Nutritional Products AG
Project TeamProfessor Peter Howe, Doctor Rachel Wong, Professor Manohar Garg, Professor Andrew Scholey
SchemeResearch Project
RoleLead
Funding Start2014
Funding Finish2014
GNoG1400950
Type Of FundingInternational - Non Competitive
Category3IFB
UONY

20133 grants / $290,000

Clinical evaluation of a novel olive leaf formulation for heart health$165,000

Funding body: Newcastle Innovation

Funding bodyNewcastle Innovation
Project TeamProfessor Peter Howe, Professor Manohar Garg, Doctor Rachel Wong, Associate Professor Lisa Wood
SchemeAdministered Research
RoleLead
Funding Start2013
Funding Finish2013
GNoG1401244
Type Of FundingInternal
CategoryINTE
UONY

Towards a fish oil-based omega-3 therapy for preventing bone loss during chronic methotrexate chemotherapy$75,000

Funding body: Channel 7 Children's Research Fund

Funding bodyChannel 7 Children's Research Fund
Project Team
SchemeResearch Grant
RoleInvestigator
Funding Start2013
Funding Finish2013
GNo
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Lipemic Index of Pork$50,000

Funding body: CRC for High Integrity Australian Pork

Funding bodyCRC for High Integrity Australian Pork
Project TeamProfessor Manohar Garg, Associate Professor Lisa Wood, Professor Peter Howe
SchemeInnovative Research
RoleInvestigator
Funding Start2013
Funding Finish2013
GNoG1201031
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

20122 grants / $373,875

Effect of pork consumption on cardiometabolic health, food cravings, cognition and psychological wellbeing in individuals with type 2 diabetes. $358,875

Funding body: CRC Pork

Funding bodyCRC Pork
Project Team
SchemeFunds granted
RoleInvestigator
Funding Start2012
Funding Finish2013
GNo
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Volunteer’s attitudes towards consumption of fresh Australian pork $15,000

Funding body: CRC Pork

Funding bodyCRC Pork
Project Team
SchemeFunds granted
RoleInvestigator
Funding Start2012
Funding Finish2013
GNo
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

20114 grants / $316,000

iWhyalla (Intervention Whyalla): a workplace-based obesity and diabetes primary and secondary prevention trial$100,000

Funding body: Department of Health

Funding bodyDepartment of Health
Project Team
SchemeUniversity Department of Rural Health Scheme research grant
RoleInvestigator
Funding Start2011
Funding Finish2013
GNo
Type Of FundingInternal
CategoryINTE
UONY

Pulse-rich foods for cognitive function and cardiometabolic health$100,000

Funding body: Grains Research and Development Corporation

Funding bodyGrains Research and Development Corporation
Project Team
SchemeResearch Grant
RoleInvestigator
Funding Start2011
Funding Finish2012
GNo
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Lutein-enriched milk and physical activity participation in older adults$61,000

Funding body: Meiji Dairies

Funding bodyMeiji Dairies
Project Team
SchemeFunds granted
RoleLead
Funding Start2011
Funding Finish2013
GNo
Type Of FundingInternational - Non Competitive
Category3IFB
UONY

Effectiveness of cycloid vibration therapy for promoting exercise recovery$55,000

Funding body: Advanced Lifestyle International

Funding bodyAdvanced Lifestyle International
Project Team
SchemeFunds granted
RoleInvestigator
Funding Start2011
Funding Finish2011
GNo
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

20105 grants / $1,022,031

Pathophysiology and alternative preventative strategy for breast cancer chemotherapy-induced bone loss$521,706

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project Team
SchemeProject Grant
RoleInvestigator
Funding Start2010
Funding Finish2015
GNo
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Effects of omega-3 fatty acids and micronutrients on learning and behaviour of Indigenous Australian children from a remote community school$320,325

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project Team
SchemeLinkage Projects
RoleInvestigator
Funding Start2010
Funding Finish2011
GNo
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Evaluation of peanuts as a source of bioactive nutrients for enhancement of endothelial function and cognitive performance$110,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project Team
SchemeLinkage Projects
RoleInvestigator
Funding Start2010
Funding Finish2013
GNo
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Nutrient therapies for preserving bone growth and preventing chemotherapy-induced bone loss in early development.$65,000

Funding body: Channel 7 Children's Research Foundation

Funding bodyChannel 7 Children's Research Foundation
Project Team
SchemeResearch Grant
RoleInvestigator
Funding Start2010
Funding Finish2010
GNo
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Bioactive nutrients in peanuts$5,000

Funding body: University of South Australia

Funding bodyUniversity of South Australia
Project Team
SchemeUniSA Linkage Project Development Incentive Grant:
RoleInvestigator
Funding Start2010
Funding Finish2013
GNo
Type Of FundingInternal
CategoryINTE
UONY

20095 grants / $2,216,646

Capturing the therapeutic value of dairy bioactives$2,035,000

Funding body: The Government of Victoria

Funding bodyThe Government of Victoria
Project Team
SchemeVictoria's Science Agenda Investment Fund
RoleInvestigator
Funding Start2009
Funding Finish2010
GNo
Type Of FundingOther Public Sector - State
Category2OPS
UONY

Acute effects of Resvida on circulatory function$65,000

Funding body: DSM Nutritional Products

Funding bodyDSM Nutritional Products
Project Team
SchemeFunds granted
RoleLead
Funding Start2009
Funding Finish2009
GNo
Type Of FundingInternational - Non Competitive
Category3IFB
UONY

Protective effects of antidote folinic acid in methotrexate chemotherapy induced bone growth defects$65,000

Funding body: Channel 7 Children's Research Foundation of South Australia

Funding bodyChannel 7 Children's Research Foundation of South Australia
Project Team
SchemeProject Grant
RoleInvestigator
Funding Start2009
Funding Finish2009
GNo
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Chronic effects of Resvida on circulatory function$27,000

Funding body: DSM Nutritional Products

Funding bodyDSM Nutritional Products
Project Team
SchemeFunds granted
RoleLead
Funding Start2009
Funding Finish2009
GNo
Type Of FundingInternational - Non Competitive
Category3IFB
UONY

The effect of regular consumption of pork on body composition. $24,646

Funding body: CRC Pork

Funding bodyCRC Pork
Project Team
SchemeFunds granted
RoleInvestigator
Funding Start2009
Funding Finish2010
GNo
Type Of FundingCRC - Cooperative Research Centre
Category4CRC
UONY

20083 grants / $860,000

Omega-3 fatty acid supplementation for symptoms of depression in cardiovascular disease$465,000

Funding body: National Heart Foundation of Australia

Funding bodyNational Heart Foundation of Australia
Project Team
SchemeStrategic Research Program
RoleInvestigator
Funding Start2008
Funding Finish2009
GNo
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Metabolic health benefits of low fat dairy products $300,000

Funding body: Department of Further Education, Employment, Science and Technology SA & Manitoba Govt

Funding bodyDepartment of Further Education, Employment, Science and Technology SA & Manitoba Govt
Project Team
SchemeFunds granted
RoleLead
Funding Start2008
Funding Finish2011
GNo
Type Of FundingOther Public Sector - State
Category2OPS
UONY

Effects of Neuravena® on cerebral blood flow & cognitive performance$95,000

Funding body: Frutarom Switzerland Ltd

Funding bodyFrutarom Switzerland Ltd
Project Team
SchemeFunds granted
RoleInvestigator
Funding Start2008
Funding Finish2009
GNo
Type Of FundingInternational - Non Competitive
Category3IFB
UONY

20075 grants / $2,498,000

Building a fit and healthy South Australia$1,318,000

Funding body: The Government of South Australia

Funding bodyThe Government of South Australia
Project Team
SchemeSouth Australian Premier’s Science and Research Fund
RoleInvestigator
Funding Start2007
Funding Finish2010
GNo
Type Of FundingOther Public Sector - State
Category2OPS
UONY

Dairy Proteins: Effects on athletic performance and recovery$417,000

Funding body: MG Nutritionals Pty Ltd.

Funding bodyMG Nutritionals Pty Ltd.
Project Team
SchemeFunds granted
RoleInvestigator
Funding Start2007
Funding Finish2009
GNo
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Cognitive and behavioural benefits of omega-3 fatty acid supplementation across the lifespan$381,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project Team
SchemeLinkage Projects
RoleLead
Funding Start2007
Funding Finish2010
GNo
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Fresh pork and cardiometabolic health $318,000

Funding body: CRC Pork

Funding bodyCRC Pork
Project Team
SchemeFunds granted
RoleLead
Funding Start2007
Funding Finish2007
GNo
Type Of FundingCRC - Cooperative Research Centre
Category4CRC
UONY

Improving erythrocyte omega-3 fatty acid profiles and health status in adults through increased consumption of canned tuna$64,000

Funding body: Seafood CRC/Simplot Australia

Funding bodySeafood CRC/Simplot Australia
Project Team
SchemeCRC Research
RoleInvestigator
Funding Start2007
Funding Finish2008
GNo
Type Of FundingCRC - Cooperative Research Centre
Category4CRC
UONY

20064 grants / $523,200

Cardiovascular effects of cocoa$368,000

Funding body: Effem Foods Pty Ltd

Funding bodyEffem Foods Pty Ltd
Project Team
SchemeFood Innovation Grant
RoleLead
Funding Start2006
Funding Finish2006
GNo
Type Of FundingInternational - Non Competitive
Category3IFB
UONY

Nutrients and muscle damage$80,200

Funding body: Murray Goulburn Co-op

Funding bodyMurray Goulburn Co-op
Project Team
SchemeFunds granted
RoleLead
Funding Start2006
Funding Finish2006
GNo
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Grape Seed Polyphenols$50,000

Funding body: BioInnovation SA

Funding bodyBioInnovation SA
Project Team
SchemeBioARC Grant
RoleInvestigator
Funding Start2006
Funding Finish2006
GNo
Type Of FundingOther Public Sector - State
Category2OPS
UONY

Effects of green tea on blood glucose$25,000

Funding body: DSM Nutritional Products

Funding bodyDSM Nutritional Products
Project Team
SchemeFunds granted
RoleLead
Funding Start2006
Funding Finish2006
GNo
Type Of FundingInternational - Non Competitive
Category3IFB
UONY

20059 grants / $2,864,050

Australian Centre for Metabolic Fitness$1,950,000

Funding body: Australian Technology Network

Funding bodyAustralian Technology Network
Project Team
SchemeAustralian Technology Network (ATN) Research Challenge
RoleLead
Funding Start2005
Funding Finish2006
GNo
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Development and application of an index for substantiating health benefits of omega-3 enriched foods$401,100

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project Team
SchemeLinkage Projects
RoleLead
Funding Start2005
Funding Finish2006
GNo
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Effects of green tea on body composition$215,000

Funding body: DSM Nutritional Products

Funding bodyDSM Nutritional Products
Project Team
SchemeFunds granted
RoleInvestigator
Funding Start2005
Funding Finish2006
GNo
Type Of FundingInternational - Non Competitive
Category3IFB
UONY

Health benefits of cocoa polyphenols and exercise$105,000

Funding body: Effem Foods Pty Ltd

Funding bodyEffem Foods Pty Ltd
Project Team
SchemeFunds granted
RoleLead
Funding Start2005
Funding Finish2005
GNo
Type Of FundingInternational - Non Competitive
Category3IFB
UONY

Effect of vespa amino acid mixture on fat oxidation during exercise$73,000

Funding body: Meiji Dairies

Funding bodyMeiji Dairies
Project Team
SchemeFunds granted
RoleLead
Funding Start2005
Funding Finish2005
GNo
Type Of FundingInternational - Non Competitive
Category3IFB
UONY

Antiinflammatory and wound healing properties of emu oil$49,950

Funding body: Technology Investment Company

Funding bodyTechnology Investment Company
Project Team
SchemeFunds granted
RoleInvestigator
Funding Start2005
Funding Finish2005
GNo
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Effects of cocoa and whey protein supplements on blood pressure$35,000

Funding body: Effem Foods Pty Ltd

Funding bodyEffem Foods Pty Ltd
Project Team
SchemeFunds granted
RoleLead
Funding Start2005
Funding Finish2005
GNo
Type Of FundingInternational - Non Competitive
Category3IFB
UONY

Glycaemic index of waxy barley products$20,000

Funding body: Grains Research and Development Corporation

Funding bodyGrains Research and Development Corporation
Project Team
SchemeResearch Grant
RoleInvestigator
Funding Start2005
Funding Finish2005
GNo
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Impact of dietary omega-3 fatty acid supplementation on asymmetric dimethylarginine (ADMA), a novel cardiovascular risk factor$15,000

Funding body: University of South Australia

Funding bodyUniversity of South Australia
Project Team
SchemeUniSA Australian Competitive Grant (ACG) Development Scheme
RoleInvestigator
Funding Start2005
Funding Finish2005
GNo
Type Of FundingInternal
CategoryINTE
UONY

20045 grants / $114,500

Development and Application of an Omega-3 Index$50,000

Funding body: Bartlett Grain

Funding bodyBartlett Grain
Project Team
SchemeFunds granted
RoleLead
Funding Start2004
Funding Finish2006
GNo
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Health benefits of cocoa polyphenols and exercise $25,000

Funding body: University of South Australia

Funding bodyUniversity of South Australia
Project Team
SchemeARC Near Miss Grant Scheme
RoleLead
Funding Start2004
Funding Finish2004
GNo
Type Of FundingInternal
CategoryINTE
UONY

Effect of novel nutrient on glycaemic index $22,000

Funding body: Wacker Chemie GmbH

Funding bodyWacker Chemie GmbH
Project Team
SchemeFunds granted
RoleInvestigator
Funding Start2004
Funding Finish2004
GNo
Type Of FundingInternational - Non Competitive
Category3IFB
UONY

Prenatal alcohol and cardiovascular risk $10,000

Funding body: University of Adelaide

Funding bodyUniversity of Adelaide
Project Team
SchemeNHMRC Near Miss Grant Scheme
RoleLead
Funding Start2004
Funding Finish2004
GNo
Type Of FundingInternal
CategoryINTE
UONY

APAI proposal and project proposal$7,500

Funding body: University of South Australia

Funding bodyUniversity of South Australia
Project Team
SchemeUniSA Linkage Project Incentive Scheme
RoleLead
Funding Start2004
Funding Finish2004
GNo
Type Of FundingInternal
CategoryINTE
UONY

20031 grants / $283,000

Development and nutritional evaluation of novel foods based on a unique combination of soy and dairy products.$283,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project Team
SchemeLinkage Projects
RoleInvestigator
Funding Start2003
Funding Finish2006
GNo
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

20024 grants / $1,496,000

Development and evaulation of novel foods enriched with very long chain omega-3 fatty acids$616,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project Team
SchemeLinkage Projects
RoleLead
Funding Start2002
Funding Finish2004
GNo
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Smart Foods$368,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project Team
SchemeARC Centres of Excellence
RoleLead
Funding Start2002
Funding Finish2006
GNo
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Human Physiology & Nutrition Research Facility for assessment of metabolic status and vascular function$270,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project Team
SchemeLinkage Infrastructure Equipment & Facilities (LIEF)
RoleLead
Funding Start2002
Funding Finish2002
GNo
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Development of novel omega-3 enriched poultry products$242,000

Our core research on modifying fatty acid composition of poultry tissues and preliminary studies with our industry partner's proprietary fishmeal product (PorcOmega) have indicated the feasibility of producing novel meat products and eggs with high w-3 contents, which would qualify to carry a new nutrition label. We now propose, in collaboration with our industry partner, to assess the viability of producing such products
Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project Team
SchemeLinkage Projects
RoleLead
Funding Start2002
Funding Finish2003
GNo
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

20001 grants / $78,240

Smart Foods for an aging populations$78,240

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project Team
SchemeStrategic Partnerships with Industry - Research and Training Scheme
RoleInvestigator
Funding Start2000
Funding Finish2002
GNo
Type Of FundingNot Known
CategoryUNKN
UONY

19991 grants / $1,757,000

Smart Foods$1,757,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project Team
SchemeARC Centres of Excellence
RoleLead
Funding Start1999
Funding Finish2001
GNo
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY
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Research Supervision

Current Supervision

CommencedResearch Title / Program / Supervisor Type
2014Lifestyle interventions to counteract cognitive decline in diabetes
Human Biology, Faculty of Health and Medicine
Principal Supervisor
2012Systemic and cerebral vasodilator function in sedentary adults
Biological Sciences, University of South Australia
Co-Supervisor
2012Heart rate response to exercise as an index of cardiovascular health
Biological Sciences, University of South Australia
Co-Supervisor
2012Effect of perceptually-regulated exercise training on endothelial function and exercise motivation
Biological Sciences, University of South Australia
Co-Supervisor
2012Tracking Training Status in Competitive Cyclists using Heart Rate Parameters
Biological Sciences, University of South Australia
Co-Supervisor
2012Omega-3 fatty acid supplementation as adjunct therapy for chronic obstructive pulmonary disease
Biological Sciences, University of South Australia
Co-Supervisor
2011Evaluation of peanuts for enhancement of endothelial function and cognitive performance
Biological Sciences, University of South Australia
Co-Supervisor
2010Acute and chronic effects of vasoactive nutrients on cardiovascular biomarkers and cognitive function
Biological Sciences, University of South Australia
Co-Supervisor
2010Protective effects of fish oil, genistein or combination on bone in MTX chemotherapy rat models.
Biological Sciences, University of South Australia
Co-Supervisor
2007Whey protein supplementation: Effects on muscle hypertrophy, athletic performance and recovery
Biological Sciences, University of South Australia
Co-Supervisor

Past Supervision

YearResearch Title / Program / Supervisor Type
2011Heart rate assessment of fatigue status following an intensive 2 week exercise intervention
Biological Sciences, University of South Australia
Co-Supervisor
2010Investigation of the cognitive and behavioural benefits n-3 PUFA supplementation across the lifespan
Biological Sciences, University of South Australia
Co-Supervisor
2010Efficacy of cycloid vibration therapy for promoting exercise recovery
Biological Sciences, University of South Australia
Co-Supervisor
2010Obesity - the new disability?
Biological Sciences, University of South Australia
Co-Supervisor
2010Developing an index of physiological recovery following exercise
Biological Sciences, University of South Australia
Co-Supervisor
2010Relationshipsbetween endothelial dysfunction in cerebral and peripheral arteries
Biological Sciences, University of South Australia
Co-Supervisor
2009Acute effects of resveratrol on circulatory function
Biological Sciences, University of South Australia
Co-Supervisor
2008Effect of endothelial vasodilator function on blood pressure response to exercise
Biological Sciences, University of South Australia
Co-Supervisor
2008Effect of dietary Omega-3 polyunsaturated fatty acids on experimental periodontitis in the mouse.
Dentistry, University of Adelaide
Co-Supervisor
2008Combined effect of cocoa polyphenols and regular exercise on body composition and cardiovascular risk.
Biological Sciences, University of Adelaide
Co-Supervisor
2008Dietary combinations capable of lowering cardiovascular risk factors
Biological Sciences, University of Wollongong
Co-Supervisor
2008Managing Obesity and Associated Health Issues - A Community-based Program for Change
Biological Sciences, University of South Australia
Co-Supervisor
2008Inflammatory markers in metabolic syndrome
Biological Sciences, University of Adelaide
Co-Supervisor
2007Evaluation of health benefits of soy isoflavones
Biological Sciences, University of Adelaide
Co-Supervisor
2006Cognitive Behavioural Therapy to Treat Overweight and Obesity in Adolescents
Biological Sciences, University of South Australia
Co-Supervisor
2006Development and application of an index for substantiating health benefits of omega-3 enriched foods
Biological Sciences, University of Adelaide
Co-Supervisor
2006 Health benefits associated with eating pork enriched with omega-3 fatty acids
Biological Sciences, University of Adelaide
Co-Supervisor
2006Diet And Exercise Interventions To Improve Cardiovascular Health
Biological Sciences, University of Adelaide
Co-Supervisor
2005Evaluation of anti-inflammatory properties of emu oil in humans.
Biological Sciences, University of South Australia
Co-Supervisor
2004Effects of omega-3 supplementation on endurance performance in elite athletes
Biological Sciences, University of South Australia
Co-Supervisor
2004Predictors of recovery from depression
Biological Sciences, University of Wollongong
Co-Supervisor
2004Pulsetrace Assessment of Vascular Function During Exercise
Biological Sciences, University of South Australia
Co-Supervisor
2004Effect of Exercise and Omega-3 Supplementation on Immune responses in the Metabolic Syndrome
Biological Sciences, University of Adelaide
Co-Supervisor
2003The Potential of Lyprinol as a Preventative Treatment of Inflammatory Bowel Disease
Biological Sciences, University of Adelaide
Co-Supervisor
2003Digital volume pulse oximetery: a reliable assessor of endothelial function and arterial compliance?
Biological Sciences, University of South Australia
Co-Supervisor
2002Dietary fish oil supplementation alters rate pressure product in trained cyclists
Biological Sciences, University of Wollongong
Co-Supervisor
Edit

News

Menopause

Study aims to ease menopausal symptoms

April 27, 2015

Can the health supplement resveratrol curb the notorious hot flushes, insomnia, irritability and occasional mental lapses that often accompany menopause?

Volunteers required to test mental function in type 2 diabetes

Diabetes study testing nutritional approach to delay cognitive decline

January 8, 2015

Researchers in the Clinical Nutrition Research Centre at the University of Newcastle are seeking people with type 2 diabetes to take a new nutritional supplement designed to stimulate blood flow in the brain and reduce the threat of mental impairment.

Are fish oil supplements putting you at risk of prostate cancer?

July 19, 2013

By Peter Howe, Director of the Clinical Nutrition Research Centre, University of Newcastle

A report published in the Journal of the National Cancer Institute late last week shows a potential link between omega-3 fatty acids and the risk of developing prostate cancer.

Professor Peter Howe

Position

Research Professor
Director, Clinical Nutrition Research Centre
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine

Focus area

Nutrition and Dietetics

Contact Details

Emailpeter.howe@newcastle.edu.au
Phone(02) 4921 7309
Mobile0402 159 039

Office

RoomMS 304
BuildingMedical Sciences Building
LocationCallaghan
University Drive
Callaghan, NSW 2308
Australia
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