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Career Summary

Biography

I have a distinguished research record in the study of molecular mechanisms of synaptic plasticity in many experimental systems, particularly in studies of brain development and maturation. I have always maintained a multidisciplinary approach in my research and active collaborations with colleagues in different disciplines both in Australia and overseas. I have an international reputation in two main areas:

1. I am an internationally recognised authority on the role and regulation of the important regulatory enzyme CaMKII, as evidenced by my invitation to be a keynote speaker on this topic in an international symposium at the joint meeting of the International and European Societies for Neurochemistry in Innsbruck, Austria (August, 2005).

2. I am internationally recognised for developing the maturing chicken forebrain as an animal model for the slow maturation of brain observed in humans and for using biochemical, electrophysiological, anatomical and behavioural techniques in chickens to investigate the fundamental biological changes that occur during maturation of the brain. Evidence for my recognition is an invitation to be a major speaker, and to chair a session, at the forthcoming Brain Mechanisms, Cognition and Behaviour in Birds Satellite Conference to the IBRO (International Brain Research Organisation) World Congress of Neuroscience (July 2007). I am also an invited Editor for the special issue of Brain Research Bulletin that will publish papers from this conference.

When comparing my scientific research track record against those of others, it must be noted that I have always performed my research while holding full academic roles that required major educational and administrative input. The extent of my activities in education and curriculum development is reflected by two peer reviewed publications in the area and invitations to speak at international conferences on problem based learning. In the last 10 years I have continuously held senior academic administrative responsibilities (Assistant and Deputy Dean of the Faculty of Medicine and Health Sciences, Executive Director of the Hunter Medical Research Institute, Deputy Head of Faculty of Health) and been appointed to State and Commonwealth government advisory panels and chairmanships, including 9 years on the NHMRC Project Grants Committee.

Despite these responsibilities I have continued to publish 3-5 papers per year in high quality, international peer reviewed journals (~50% of papers appeared in journals with an impact factor above 4.8 and 70% above 3). In all, I have published more than 95 papers in high ranking international journals. The fact that much of my research has been performed in chickens accounts for the lower citation rate compared with similar work performed in mammals. My research papers have had a consistent citation rate of 70-90 per year for the last decade.

I have received multiple invitations to speak at international and national conferences including the inaugural Lawrie Austin Plenary Lecture at the 2002 meeting of the Australian Neuroscience Society.

Qualifications

  • PhD, Monash University
  • Bachelor of Science (Honours), Monash University

Research

Research keywords

  • biochemistry
  • cell biology
  • neuroscience

Research expertise

I have a distinguished research record in the study of molecular mechanisms of synaptic plasticity in many experimental systems, particularly in studies of brain development and maturation. I have always maintained a multidisciplinary approach to research and active collaborations with colleagues in different disciplines both in Australia and overseas. My research expertise is focussed in two areas:

1. I am an internationally recognised authority on the role and regulation of the important regulatory enzyme CaMKII. In this field work from my laboratory was the first to show :

  • That developmental changes in subcellular distribution of CaMKII occur independently of the developmental change in expression level of the enzyme and that the subcellular translocation is indirectly regulated by thyroid hormone
  • The existence of giant mossy fibre nerve terminals in the chicken hippocampus and of LTP and LTD at these synapses, and to show that CaMKII activation is required for presynaptic LTD at these synapses.
  • That CaMKII regulation in vivo cannot be explained by currently known mechanisms and that there is a new class of regulatory mechanism operating in vivo. This new class of control mechanisms apparently occur only a specific functionally important locations in neurons (e.g. at the PSD in association with certain receptors) and require interaction with specific local proteins. If this is true, these proteins will provide highly selective drug targets through which the activity of CaMKII could be altered at specific locations in the neuron without altering CaMKII activity elsewhere in neurons or in other cells. This could lead to neuro/psycho-active drugs with fewer side-effects. These activation of these new control mechanisms could also be used as biomarkers of disease or neuropathology.

2. I am internationally recognised for developing the maturing chicken forebrain as an animal model for the slow maturation of brain observed in humans. Work from my laboratory has demonstrated the protracted maturation of neuronal function in chicken brain using biochemical, electrophysiological and anatomical techniques and identified some fundamental changes in biological mechanisms during maturation. The chicken model for brain maturation may provide opportunities to identify the major biological factors controlling the maturation process and to test a variety of drugs or other interventions on the normal progress of this maturation. This is of relevance to a variety of neurodevelopmental disorders.

Fields of Research

CodeDescriptionPercentage
110199Medical Biochemistry And Metabolomics Not Elsewhere Classified40
110900Neurosciences40
170299Cognitive Science Not Elsewhere Classified20

Memberships

Editorial Board.

  • member since 1995 - Neurochemical Research (scientific journal)

NHMRC Committee

  • Deputy Chair of Project Grants Committee (2003-2006); Chair of Objections Subcommittee (2001-2006); - NHMRC Project Grants Committee (1997-2006); Objections Subcommittee (2000-2006); Chair of Molecular Neuroscience GRP 2006
  • Chair of Grant Review Panel 2006 - GRP Molecular and Cellular Neuroscience

Appointments

Ministerial Advisory Committee on Medical and Health Research
NSW Government (Australia)
01/01/2003 - 01/08/2006
Council of the International Society for Neurochemistry and Chair of its Committee for Aid for Neurochemistry
International Society for Neurochemistry (United Kingdom)
01/09/1991 - 01/09/1995

Invitations

Lawrie Austin Plenary Lecture
Australian Neuroscience Society, Australia (Conference Presentation - non published.)
2002
Keynote speaker and Symposium Co-Chair
International Society for Neurochemistry, Austria (Conference Presentation - non published.)
2005

Administrative

Administrative expertise

SELECTED SENIOR ADMINISTRATIVE APPOINTMENTS (since 1992)

2006 - Deputy Head of Faculty (Research), and Professor of Biomedical Sciences, Faculty of Health, University of Newcastle - responsible for coordinating research and research training across the Faculty at all campuses

1999 - 2006 Founding Executive Director, Hunter Medical Research Institute and Professor of Biomedical Sciences, Faculty of Health, The University of Newcastle - established the scientific organisation and governance foundations of HMRI, its recognition by the NSW Government as the third largest medical research institute in the state, and its infrastructure funding by NSW government on an equal footing with Sydney institutes.

1997 - 2001 Assistant Dean (Research), Faculty of Medicine & Health Sciences, University of Newcastle

Chairmanship or Sole Responsibility

2001 - 2006 Chair, Complaints Subcommittee of NH&MRC Projects Grants Committee

2003 - 2006 Deputy Chair, NH&MRC Project Grants Committee

2003 - 2004 Chair, BioFirst High Bandwidth Network Implementation Committee, NSW Government

2002 - 2003 Chair, BioFirst High Bandwidth Network Committee, NSW Government

1997 - 2001 Assistant Dean (Research) and Chair of the Faculty Research Management Committee, Faculty of Medicine and Health Sciences, University of Newcastle

1996 - 1997 Chair, Local Organising Committee for 17th Annual Conference of the Australian Neuroscience Society

1992 - 1995 Chair, International Society for Neurochemistry Committee for Aid for Neurochemistry

1984 - 1995 Editor and member of Council Executive for Australian Neuroscience Society

2006 - Deputy Chair, Research Training Committee of The University of Newcastle

Committee Membership

1997 - 2006 Project Grants Committee, National Health and Medical Research Council of Australia

2003 - 2006 Ministerial Advisory Committee on Medical and Health Research, NSW Government

2001 - 2006 Ministerial Advisory Committee on Biotechnology, NSW Government

2001 - 2006 BioFirst Awards Committee, NSW Government

1999 - 2004 Research and Development Advisory Committee, NSW Department of Health

1998 - 2006 Council of Asian Pacific Society for Neurochemistry

2003 - 2005 Cancer Research Advisory Board, Cancer Institute of NSW

1991 - 1995 Council of the International Society for Neurochemistry

1999 - 2004 Reference Group for Medical Research, Australian Business

Teaching

Teaching keywords

  • biochemistry
  • cell biology
  • neuroscience

Teaching expertise

Supervised 14 postgraduate research students and 7 postdoctoral research fellows.

Developed and taught integrated, problem based curricula for Bachelor of Medicine and Bachelor of Biomedical Science. Developed training programs for research planning and research grant preparation for postgraduate research students and university and hospital staff. Invited to speak on curriculum design and evaluation at major international centres in Europe and North America. Peer reviewed publications on problem based curriculum design:

Rostas, J.A.P. and Olson,L.G. (1997). Teaching basic sciences in an integrated curriculum: making it work. In: Imperatives in Medical Education: The Newcastle Approach. Eds. R. Henry, K. Byrne and C. Engel. University of Newcastle, Australia, pp 83-94.

Rostas, J.A.P. and Rolfe, I. (1997). Training working problem tutors for medical students. In: Imperatives in Medical Education: The Newcastle Approach, Eds. R. Henry, K. Byrne and C. Engel. University of Newcastle, Australia, pp 189-199.

External Examiner for University of Papua New Guinea Medical School (1996), Royal Australian College of Obstetricians and Gynaecologists (1989-1994), and PhD theses for Sydney, Melbourne, Monash, New England and RMIT Universities.

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Publications

No publications.

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Grants and Funding

Summary

Number of grants84
Total funding$9,688,434

For project grants received where the lead institution is other than the University of Newcastle, details are shown in italics.

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2013 (2 grants)

Ultra-Low Temperature Cryogenic Freezer$24,596
Funding Body: NHMRC (National Health & Medical Research Council)

International Society for Neurochemistry - American Society for Neurochemsity Biennial Conference, Cancun Mexico, 20 - 24 April 2013$2,000
Funding Body: University of Newcastle - Faculty of Health

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,00020132014
GNo:G1300537

2012 (4 grants)

Regulation of the cell cycle by phosphorylation dependent targeting of CaMKII$20,000
Funding Body: University of Newcastle

Project Team
Doctor Nikki Verrills, Doctor Kathryn Skelding, Professor John Rostas, Associate Professor Phillip Dickson, Conjoint Professor Keith Jones
SchemeRole
Near Miss GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020122012
GNo:G1200679

Role of CaMKII targeting in neuronal susceptibility to excitotoxic cell death$20,000
Funding Body: University of Newcastle

Project Team
Professor John Rostas, Doctor Neil Spratt, Associate Professor Phillip Dickson, Doctor Nikki Verrills
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$20,00020122012
GNo:G1200673

FT13 Future Fellowship External Applicant Support - FH$16,000
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Special Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$16,00020122012
GNo:G1201092

Asian Pacific Society for Neurochemistry/Japanese Society for Neurochemistry, Kobe, Japan, 30 September - 2 October 2012$2,000
Funding Body: University of Newcastle - Faculty of Health

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,00020122013
GNo:G1201003

2011 (5 grants)

Regulation of Breast Cancer Growth by a Novel Phosphorylation-Dependent Targeting Mechanism$35,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Kathryn Skelding, Doctor Nikki Verrills, Professor John Rostas
SchemeRole
Breast Cancer Project GrantInvestigator
Total AmountFunding StartFunding Finish
$35,00020112011
GNo:G1001005

Role of CaMKII targeting in stroke susceptibility and outcome$18,200
Funding Body: Hunter Medical Research Institute

Project Team
Professor John Rostas, Doctor Neil Spratt, Doctor Kathryn Skelding
SchemeRole
Stroke Research Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$18,20020112011
GNo:G1001013

Role of CaMKII targeting in stroke susceptibility and outcome$15,000
Funding Body: Brain Foundation (NSW Branch)

Project Team
Doctor Neil Spratt, Professor John Rostas
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$15,00020112011
GNo:G1000716

IMPLEN NanoPhotometer pearl$10,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Murray Cairns, Associate Professor Paul Tooney, Associate Professor Alan Brichta, Professor John Rostas, Emeritus Professor Patricia Michie, Conjoint Professor Keith Jones, Professor Ulli Schall, Associate Professor Phillip Dickson, Doctor Frederick Walker, Doctor Rick Thorne, Doctor Chris Dayas, Doctor Nikki Verrills, Doctor Janet Holt, Doctor Severine Roselli, Doctor Kathryn Skelding, Doctor Jude Weidenhofer, Associate Professor Liz Milward, Doctor Charles De Bock, Doctor Julie Merriman-Jones, Doctor Jing Qin Wu, Doctor Bing Liu, Mr Dan Johnstone, Ms Belinda Goldie, Ms Natalie Beveridge
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020112011
GNo:G1100030

23rd Biennial Meeting of International Society for Neurochemistry joint with the European Society for Neurochemistry, Athens, Greece, 28/8/2011 - 1/9/2011$2,000
Funding Body: University of Newcastle - Faculty of Health

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,00020112012
GNo:G1100698

2010 (4 grants)

Molecular and cellular characterisation of schizophrenia associated dysfunction in microRNA biogenesis$478,500
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Murray Cairns, Professor Rodney Scott, Associate Professor Paul Tooney, Professor John Rostas, Associate Professor Alan Brichta
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$478,50020102012
GNo:G0190196

ABI 7500 Real Time PCR System $34,000
Funding Body: NHMRC (National Health & Medical Research Council)

Waters, Ultra high performance liquid chromatography system (nano-Aquity) $30,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Mark Baker, Laureate Professor John Aitken, Professor Adam McCluskey, Associate Professor Brett Nixon, Professor John Rostas, Professor Eileen McLaughlin
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$30,00020102010
GNo:G1000051

OzBio2010 - The Molecules of Life, Melbourne Convention & Exhibition Centre, 26 September 2010 - 1 October 2010$400
Funding Body: University of Newcastle - Faculty of Health

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$40020102011
GNo:G1000742

2009 (4 grants)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000
Funding Body: ARC (Australian Research Council)

China-Australia therapeutic hypothermia in stroke (CATHS) research program: identification of diagnostic molecular markers and therapeutic targets involved in re-warming related brain injury$230,275
Funding Body: NSW Office for Science & Medical Research

Project Team
Conjoint Professor Chris Levi, Doctor Mark Baker, Doctor Neil Spratt, Professor John Rostas
SchemeRole
China-NSW Collaborative Research ProgramInvestigator
Total AmountFunding StartFunding Finish
$230,27520092009
GNo:G0190392

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000
Funding Body: ARC (Australian Research Council)

22nd Biennial Meeting of the International Society for Neurochemistry, Busan, South Korea, 23-28 August 2009$2,500
Funding Body: University of Newcastle - Faculty of Health

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,50020092009
GNo:G0190449

2008 (3 grants)

Is CaMKII autophosphorylation a mechanism of endogenous neuroprotection after stroke?$14,417
Funding Body: University of Newcastle

Project Team
Professor John Rostas, Doctor Neil Spratt
SchemeRole
Pilot GrantChief Investigator
Total AmountFunding StartFunding Finish
$14,41720082008
GNo:G0189110

Hypoxic culture chamber and low-pressure gas regulators$11,500
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Neil Spratt, Professor John Rostas, Professor Mike Calford
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$11,50020082008
GNo:G0188544

8th Biennial Meetingof the Asian-Pacific Society for Neurochemistry, Shanghai, 23/6/2008 - 26/6/2008$1,974
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,97420082008
GNo:G0189136

2007 (3 grants)

Functional Characterisation of a New Regulatory Mechanism for CaMKII at Synapses in Vivo$526,500
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor John Rostas, Associate Professor Phillip Dickson, Professor Alistair Sim
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$526,50020072009
GNo:G0186415

RQF Support for Assistant Dean (Research)$14,000
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Special Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$14,00020072007
GNo:G0187947

Brain Mechanisms, Cognition and Behaviour in Birds (official satellite to IBRO World Congress of Neuroscience, Melbourne, 12/7/2007 - 17/7/2007$1,131
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,13120072007
GNo:G0187938

2006 (5 grants)

PRC - Priority Research Centre for Bioinformatics, Biomarker Discovery & Information-Based Medicine (CIBM)$621,143
Funding Body: University of Newcastle

Project Team
Professor Pablo Moscato, Professor Rodney Scott, Professor John Rostas, Professor John Forbes, Conjoint Professor Peter Hersey, Conjoint Professor Stephen Ackland, Conjoint Professor Wayne Smith, Emeritus Professor Peter Dunkley, Conjoint Professor Leonie Ashman, Professor John Attia, Associate Professor Phillip Dickson, Associate Professor Liz Milward, Professor Alistair Sim, Associate Professor Paul Tooney, Associate Professor Regina Berretta, Conjoint Professor David Sibbritt, Conjoint Professor Chris Levi, Professor Xu Dong Zhang, Conjoint Associate Professor Patricia Crock, Conjoint Associate Professor Jeannette Lechner-Scott
SchemeRole
Priority Research CentreInvestigator
Total AmountFunding StartFunding Finish
$621,14320062013
GNo:G0186919

PRC - Priority Research Centre for Brain & Mental Health Research (CBMHR)$524,282
Funding Body: University of Newcastle

Project Team
Conjoint Professor Chris Levi, Professor Amanda Baker, Professor Mike Calford, Professor Trevor Day, Emeritus Professor Peter Dunkley, Professor Michael Hazelton, Professor Andrew Heathcote, Professor Brian Kelly, Conjoint Professor Vaughan Carr, Emeritus Professor Patricia Michie, Professor David Pow, Professor John Rostas, Professor Ulli Schall, Professor Alistair Sim, Professor Mike Startup
SchemeRole
Priority Research CentreInvestigator
Total AmountFunding StartFunding Finish
$524,28220062013
GNo:G0186947

Functional Characterisation of CaMKII Phosphorylate at a New Site in vivo$20,000
Funding Body: University of Newcastle

Project Team
Professor John Rostas, Associate Professor Phillip Dickson, Professor Alistair Sim
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$20,00020062006
GNo:G0186059

7th Biennial Meeting of the Asian Pacific Society for Neurochemistry (APSN 2006), 2-5 July 2006$1,500
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,50020062006
GNo:G0186659

BioRad Mini-PROTEAN3 Electrophoresis system$995
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Professor Leonie Ashman, Associate Professor Phillip Dickson, Emeritus Professor Peter Dunkley, Professor John Rostas, Professor Judith Scott, Professor Alistair Sim, Doctor Nikki Verrills
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$99520062006
GNo:G0187280

2005 (4 grants)

High throughput proteomics - Thermo Finnigan ProteomeX LCQ Integrated Proteomicis Workstation$207,189
Funding Body: ARC (Australian Research Council)

The Australian EEG Database - Infrastructure Support$20,000
Funding Body: Hunter Medical Research Institute

Project Team
Emeritus Professor Patricia Michie, Conjoint Associate Professor Mick Hunter, Professor John Rostas, Conjoint Associate Professor David Williams, Professor Pablo Moscato, Associate Professor Frans Henskens
SchemeRole
HMRI Brain and Mental Health Research ProgramInvestigator
Total AmountFunding StartFunding Finish
$20,00020052005
GNo:G0185719

Mechanisms and functional consequences of glutamate receptor maturation in chicken brain and New ways of controlling CaMKII in cells$10,000
Funding Body: University of Newcastle

Project Team
Professor John Rostas, Professor Ulli Schall
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00020052005
GNo:G0184707

20th Biennial International Society for Neurochemistry (ISN) and European Society for Neurochemistry (ESN) Conference, 21-26 August 2005$2,500
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,50020052005
GNo:G0185425

2004 (3 grants)

Differential regulation of two modes of exocytosis by protein phosphatases$393,750
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Alistair Sim, Professor John Rostas
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$393,75020042006
GNo:G0182930

Biacore3000-Expansion of Proteomics Facility$187,341
Funding Body: ARC (Australian Research Council)

Project Team
Professor Alistair Sim, Laureate Professor John Aitken, Emeritus Professor Peter Dunkley, Professor John Rostas, Associate Professor Phillip Dickson, Conjoint Professor Leonie Ashman, Professor Roger Smith, Professor Gordon Burns, Professor Adam McCluskey, Associate Professor Paul Tooney, Dr Fraser Ross, Conjoint Professor Ray Rose
SchemeRole
Linkage Infrastructure Equipment & Facilities (LIEF)Investigator
Total AmountFunding StartFunding Finish
$187,34120042004
GNo:G0183030

12th International Conference on Second Messengers and Phosphoproteins, 3-7 August 2004, Canada$2,400
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,40020042004
GNo:G0184474

2003 (4 grants)

The Emlyn and Jennie Thomas Fund for Postgraduate Sholarships in Cardiovascular Health.$500,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor John Rostas
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$500,00020032003
GNo:G0182686

Quantitative EEG analysis of the maturational changes associated with childhood and juvenile absence epilepsy.$28,000
Funding Body: John Hunter Children`s Hospital Research Foundation

Project Team
Doctor Robert Smith, Conjoint Associate Professor Mick Hunter, Professor John Rostas
SchemeRole
Research Grant (Defunct)Investigator
Total AmountFunding StartFunding Finish
$28,00020032003
GNo:G0181850

New Control Mechanism for CaMKII in Nerve Cells: regulating the regulator.$13,000
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$13,00020032003
GNo:G0182499

Characterisation of the Pre-pulse Inhibition learning paradigm in chickens$6,000
Funding Body: University of Newcastle

Project Team
Conjoint Associate Professor Mick Hunter, Professor John Rostas
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$6,00020032003
GNo:G0182457

2002 (4 grants)

Proteomic and Genomic Analysis Facility.$473,332
Funding Body: Wellcome Trust

Project Team
Professor Alistair Sim, Emeritus Professor Peter Dunkley, Professor John Rostas, Professor Rodney Scott, Conjoint Professor Leonie Ashman
SchemeRole
Major Equipment AwardInvestigator
Total AmountFunding StartFunding Finish
$473,33220022004
GNo:G0181527

Mechanisms of Glutamate Receptor Maturation in Chicken Brain$417,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor John Rostas, Dr Martin Cammarota, Professor Alistair Sim, Conjoint Associate Professor Mick Hunter, Professor Ulli Schall
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$417,00020022004
GNo:G0180913

Peltier Thermal Cycler and associated equipment essential for establishing cDNA Retroviral Libraries$21,315
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Leonie Ashman, Dr Petranel Ferrao, Professor Gordon Burns, Professor Alistair Sim, Emeritus Professor Peter Dunkley, Professor John Rostas, Associate Professor Phillip Dickson, Professor Dirk Van Helden, Dr Perry Hartfield
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$21,31520022002
GNo:G0181919

Biochemical characerization of the DTAL learning task: comparison between immature and mature chickens$12,000
Funding Body: University of Newcastle

Project Team
Professor John Rostas, Conjoint Associate Professor Mick Hunter
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$12,00020022002
GNo:G0181301

2001 (3 grants)

HMRI Infrastructure Block Grant.$2,100,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor John Rostas
SchemeRole
NSW Dept Health - Infrastructure FundingChief Investigator
Total AmountFunding StartFunding Finish
$2,100,00020012003
GNo:G0180712

Reciprocal Regulation of Kinases and Phosphatases in Long Term Synaptic Plasticity$15,000
Funding Body: University of Newcastle

Project Team
Professor John Rostas, Professor Alistair Sim, Professor Robert Callister
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$15,00020012001
GNo:G0180078

Joint Meeting of ISN & ASN & Satellite, Argentina 26 August - 4 September 2001$2,500
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,50020012001
GNo:G0181432

2000 (3 grants)

Neurolucida Imaging System.$24,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Loris Chahl, Associate Professor Paul Tooney, Emeritus Professor Peter Dunkley, Professor John Rostas
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$24,00020002000
GNo:G0179167

Regulating the Regulator: Using Immunochemical Tools to Reveal How CaMPK-II is Controlled by Phosporylation In Vivo.$13,500
Funding Body: University of Newcastle

Project Team
Professor John Rostas, Emeritus Professor Peter Dunkley, Dr Martin Cammarota, Dr Sabine Fieuw-Makaroff
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$13,50020002000
GNo:G0178869

On the mechanisms involved in learning and memory in the mature chicken brain.$7,000
Funding Body: University of Newcastle

Project Team
Conjoint Associate Professor Mick Hunter, Professor John Rostas
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$7,00020002000
GNo:G0178909

1999 (6 grants)

Confocal Laser Scanning Microscope Facility.$203,107
Funding Body: ARC (Australian Research Council)

Project Team
Laureate Professor John Aitken, Emeritus Professor John Patrick, Conjoint Professor Christina Offler, Associate Professor David McCurdy, Conjoint Professor Ray Rose, Doctor Tim Roberts, Conjoint Associate Professor Russell Jones, Doctor John Clulow, Professor John Rostas, Professor Alistair Sim, Professor Gordon Burns, Conjoint Professor Loris Chahl, DR DAVID KAY
SchemeRole
Large Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$203,10719991999
GNo:G0177945

FPLC Protein Purification System$16,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Alistair Sim, Professor John Rostas, Emeritus Professor Peter Dunkley, Associate Professor Phillip Dickson
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$16,00019991999
GNo:G0180790

Characterisation of giant mossy fibre-like nerve terminal in chicken hippocampus.$12,500
Funding Body: ARC (Australian Research Council)

Project Team
Professor John Rostas
SchemeRole
Small GrantChief Investigator
Total AmountFunding StartFunding Finish
$12,50019991999
GNo:G0178123

Development of a Versatile, Sensitive, Non-Isotopoic Method for Detecting Phosphorylated and Glycosylated Serines in Proteins and Peptides$10,000
Funding Body: University of Newcastle

Project Team
Professor John Rostas, Professor Adam McCluskey
SchemeRole
Collaborative Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00019991999
GNo:G0178350

RMC Collab Partner.Development of a Versatile, Sensitive, Non-Isotopic Method for Detecting Phosphorylated and Glucosylated Serines in Proteins & Peptides.$10,000
Funding Body: Bio-Rad Laboratories Pty Ltd (Australia)

Project Team
Professor John Rostas, Professor Adam McCluskey
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00019991999
GNo:G0178764

Joint Meeting of the International & European Societies for Neurochemistry, Berlin, Germany.$2,400
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,40019991999
GNo:G0180516

1998 (5 grants)

Protein phosphorylation events in long term potentiation$339,775
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor John Rostas
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$339,77519982000
GNo:G0177187

Molecular Dynamics Storm 860 Tri-mode Analysis System$35,000
Funding Body: Ramaciotti Foundations

Project Team
Professor Alistair Sim, Professor John Rostas, Emeritus Professor Peter Dunkley, Dr Stephen Bunn, Dr Tat Cheah, Conjoint Professor Kenneth Beagley, Conjoint Professor Ray Rose, Professor Judith Scott, Doctor Cheng Chan, Professor Roger Smith
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$35,00019981998
GNo:G0177453

Investigation of giant mossy fibre-like nerve terminals in chicken hippocampus.$14,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor John Rostas
SchemeRole
Small GrantChief Investigator
Total AmountFunding StartFunding Finish
$14,00019981998
GNo:G0177356

Pharmaco-behavioural study of changes in the biochemical pathways involved in learning and memory in immature and mature chicken brain.$14,000
Funding Body: University of Newcastle

Project Team
Conjoint Associate Professor Mick Hunter, Professor John Rostas
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$14,00019981998
GNo:G0177408

16th International Australasian Winter Conference on Brain Research and the Satellite Symposium on Learning and Memory Mechanisms$1,115
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,11519981998
GNo:G0180590

1997 (4 grants)

Characteristation of Novel Molecular Probes for Protein Phosphatases.$160,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Alistair Sim, Professor John Rostas, Dr R Capon
SchemeRole
Large GrantInvestigator
Total AmountFunding StartFunding Finish
$160,00019971999
GNo:G0176188

Application of a new non-isotopic techniequ to measure changes in protein phosphorylation in vivo.$15,000
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$15,00019971997
GNo:G0177494

Molecular mechanisms underlying presynaptic long-term potentiation in hippocampal synaptosomes.$10,000
Funding Body: ARC (Australian Research Council)

Project Team
Imre Lengyel, Professor John Rostas
SchemeRole
Small GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00019971997
GNo:G0176720

Joint Meeting of the International Society for Neurochemistry and the American Society for Neurochemistry, Boston, USA, 20-26 July 1997$2,958
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,95819971997
GNo:G0179556

1996 (3 grants)

Establishment of techniques for preparing genetically engineered molecules to study the regulation of neuronal and cellular function$12,000
Funding Body: University of Newcastle

Project Team
Professor John Rostas, Emeritus Professor Peter Dunkley, Professor Robert Callister
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$12,00019961996
GNo:G0175744

Combined biochemical and electrophysiological investigations of the molecular mechanisms responsible for synaptic plasticity$11,620
Funding Body: Ramaciotti Foundations

Project Team
Professor John Rostas
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$11,62019961996
GNo:G0175557

Avian Brain and Behaviour Meeting, Tihany, Hungary, 25-28 August 1996$1,500
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,50019961996
GNo:G0176529

1995 (5 grants)

Subcellular pools of CaMPK-II and protein phosphorylation: Role in long term potentiation.$312,026
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor John Rostas, Conjoint Associate Professor John Heath
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$312,02619951997
GNo:G0174555

95APP. High resolution purification of intra-cellular signalling proteins from brain by FPLC.$20,000
Funding Body: Ramaciotti Foundations

Project Team
Professor Alistair Sim, Emeritus Professor Peter Dunkley, Professor John Rostas
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00019951995
GNo:G0174696

Establishment of new model systems and techniques for studying neurotransmision$9,000
Funding Body: University of Newcastle

Project Team
Emeritus Professor Peter Dunkley, Professor John Rostas, Dr B Walmsley
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$9,00019951995
GNo:G0174902

Phosphorylation of glycoprotein GP-180:- Implications for NMDA-type glutamate receptor function$9,000
Funding Body: University of Newcastle

Project Team
Professor Alistair Sim, Professor John Rostas
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$9,00019951995
GNo:G0174918

15th Biennial Meeting of the International Society for Neurochemistry (Kyoto, Japan)$2,360
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,36019951995
GNo:G0175540

1994 (4 grants)

Mechanism of Nitric Oxide Modulation of Secretion in Autonomic Ganglia$22,500
Funding Body: National Heart Foundation of Australia

Project Team
Emeritus Professor Peter Dunkley, Professor John Rostas
SchemeRole
Grant-In-AidInvestigator
Total AmountFunding StartFunding Finish
$22,50019941994
GNo:G0175235

Establishment of new model systems and techniques for studying neurotransmission$13,500
Funding Body: ARC (Australian Research Council)

Project Team
Professor John Rostas, Emeritus Professor Peter Dunkley, Dr B Walmsley
SchemeRole
Small GrantChief Investigator
Total AmountFunding StartFunding Finish
$13,50019941994
GNo:G0174822

'Physiological & Biochemical Basis of Brain Activity', St. Petersburg, Russia, 22 - 24 June 1994$2,500
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,50019941994
GNo:G0174519

Physiological & Biochemical Basis of Brain Activity - St Petersburg - 22-24 June 1994$2,500
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,50019941994
GNo:G0175126

1993 (2 grants)

Advance Warning Of Cyanobacterial Activity$119,637
Funding Body: Urban Water Research Association

Project Team
Professor Alistair Sim, Professor John Rostas
SchemeRole
Research GrantInvestigator
Total AmountFunding StartFunding Finish
$119,63719931994
GNo:G0173334

'14th Biennial Meeting of the Int. Soc. for Neurochemistry', Montpellier, France, 22 - 27 August 1993$1,093
Funding Body: University of Newcastle

Project Team
Professor John Rostas
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,09319931993
GNo:G0174413

1992 (2 grants)

Molecular Mechanisms Of Neuronal Maturation: A Model Of Synaptic Plasticity$304,483
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor John Rostas, Conjoint Associate Professor John Heath
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$304,48319921994
GNo:G0174272

92,93,94GRANT. The Regulation Of Protein Phosphatases In The Brain$183,006
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Alistair Sim, Emeritus Professor Peter Dunkley, Professor John Rostas
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$183,00619921994
GNo:G0174274

1991 (2 grants)

Molecular Mechanisms Of Neuronal Maturation$99,562
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor John Rostas
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$99,56219911991
GNo:G0173956

Beta Scintillation Spectrometer$37,552
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor David Powis, Emeritus Professor Peter Dunkley, Professor John Rostas, Emeritus Professor Anthony Smith
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$37,55219911991
GNo:G0173965
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Research Supervision

Number of current supervisions0

For supervisions undertaken at an institution other that the University of Newcastle, details are shown in italics, and the institution name is listed below the program name.

Past Supervision

YearProgramSupervisor TypeResearch Title
2013M Philosophy (Medical Biochem)Principal SupervisorEffects of Multi-site Phosphorylation on CaMKII Function
2008PhD (Psychology - Science)Co-SupervisorBrain Maturation in Chickens: Biochemical, Behavioural and Electrophysiological Investigations
2004PhD (Medical Biochemistry)Co-SupervisorDifferential Regulation of Two Modes of Synaptic Vesicle Exocytosis by Protein Phosphorylation
2001PHD Biochemistry & Cell Biology
University of Newcastle
Principal SupervisorIdentification of brain proteins whose phosphorylation is regulated by NO and cGMP
1999PHD Biochemistry & Cell Biology
University of Newcastle
Principal SupervisorSynaptic plasticity in chicken hippocampus.
1998PHD Behavioural Science N.E.C.
University of Otago, NZ
Co-SupervisorMechanisms responsible for neuronal compensation following unilateral labarynthectomy in the guinea pig.
1997PHD Biochemistry & Cell Biology
University of Newcastle
Principal Supervisor. Changes in glutamate receptors in chicken forebrain during maturation.
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Professor John Rostas

Work Phone(02) 4921 5615
Fax(02) 4921 5669
Email
PositionDeputy Head of Faculty Research
Faculty of Health and Medicine
The University of Newcastle, Australia
Office
LS3-40 and BB2-04,
Life Sciences and Bowman,
Callaghan
University Drive
Callaghan NSW 2308
Australia
URL:www.newcastle.edu.au/profile/john-rostas