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Career Summary

Biography

Dr Walker obtained his PhD from the Univeristy of Newcastle in the field of Neuroimmunology in 2006. Dr Walker then joined the systems neuroscience laboratory of Professor Trevor Day, in the School of Biomedical Sciences & Pharmacy, as an NHMRC funded postdoctoral reseacher. During this time he investigated brain mechanisms that underpin individual differences in vulnerability to psychological stress. In 2007 Dr Walker was awarded an NHMRC Biomedical (Peter Doherty) Postdoctoral Fellowship.  During this time his work became increasingly focused on the role of glia and neuroimmune alerations in mood disturances. In 2009 established the Affective Neuroscience and Neuroimmunology research group at the University of Newcastle, Australia. Over the past several years Dr Walker’s research has been focused on the role of glia in complex behaviour and mood disturbances. He has established himself as an emerging researcher leader in the field.  He is regularly invited to speak at national and international conferences, and is called upon to review NHMRC grant applications and manuscripts.  His work is currently supported by the NHMRC and the Hunter Medical Research Institute.

Qualifications

  • PhD, University of Newcastle, 31/01/2006
  • Bachelor of Arts (Honours), University of Newcastle, 03/12/1999

Research

Research keywords

  • Depression
  • Microglia
  • Neuroinflammation
  • Neuron-Glia interactions
  • Psychoneuroimmunology
  • Stress

Research expertise

The primary objective of our research group is to understand the relationship between psychological stress, neuroinflammation and alterations in glia. Our interfaces with a number of disease processes including; stroke, Alzheimers, and depression. Our research makes uses of a large variety of techniques spanning from the analysis of individual genes of interest through to the behavioural level. Our research laboratories, situated at with the School of Biomedical Sciences and Pharmacy, are ideally equipped with state of the art equipment to undertake these multi-level investigations.

Languages

  • English

Fields of Research

CodeDescriptionPercentage
110900Neurosciences100

Memberships

Conference Chair

  • Member - Autonomic Neuroscience Workshop

Appointments

Peter Doherty Biomedical Fellow
National Health & Medical Research Council (Australia)
01/01/2007 - 01/12/2010
University of Newcastle Research Fellow
University of Newcastle (Australia)
01/01/2007

Awards

Research Award.

2005Psychoneuroimmunology Research Society
Psychoneuroimmunology Research Society (United States)
Excellence in research

Invitations

The role of microglia in cognitive disturbance: a new frontier in the neurobiology of stress.
University of Neewcastle, Australia (Invited Presenter)
2012

Collaboration

Dr Murray Cairns (University of Newcastle): Genome wide profiling of stress induced changes within the brain

Professor Trevor Day (Deakin University): Neuroninflammatory modulation of mood state

Professor Michael Nilsson (University of Newcastle): Glial remodelling in stroke

Administrative

Administrative expertise

Member and Animal Services User Advisory Group 2012-2014

Member of the Centre for Translational Neuroscience and Mental Health management committee (Chair of the Affective and Addictive Disorders subgroup)

Teaching

Teaching keywords

  • Biomedical Statistics
  • Learning and Memory
  • Neuroscience
  • Research Design and Methodology

Teaching expertise

I have been fortunate to contribute to the teaching of the following courses:

HUBS 1405 - Introduction to Biomedical Statistics

HUBS 3403 - Neuroscience

HUBS 3410 - Advanced Research Skills

MED 2000 - Frontal Lobes and Cognition

PSYCH 3040 - Advanced Psychobiology

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Highlighted Publications

For publications that are currently unpublished or in-press, details are shown in italics.

YearCitationAltmetricsLink
2010Tynan R, Naicker S, Hinwood M, Nalivaiko E, Buller KM, Pow DV, et al., 'Chronic stress alters the density and morphology of microglia in a subset of stress-responsive brain regions', Brain Behavior and Immunity, 24 1058-1068 (2010) [C1]
2011Hinwood M, Tynan R, Day TA, Walker FR, 'Repeated social defeat selectively increases DeltaFosB expression and histone H3 acetylation in the infralimbic medial prefrontal cortex', Cerebral Cortex, 21 262-271 (2011) [C1]
2012Hinwood M, Morandini J, Day TA, Walker FR, 'Evidence that microglia mediate the neurobiological effects of chronic psychological stress on the medial prefrontal cortex', Cerebral Cortex, 22 1442-1454 (2012) [C1]

Co-authors: Trevor Day

Publications

For publications that are currently unpublished or in-press, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Chapter (2 outputs)

YearCitationAltmetricsLink
2013Walker FR, Nalivaiko E, Day TA, 'Stress and inflammation: An emerging story', Nutrition and Physical Activity in Inflammatory Diseases, CABI, Oxfordshire 260-272 (2013) [B1]
2012Day TA, Walker FR, 'An introduction to the neurobiology of emotions and social behavior', The Mouse Nervous System, Academic Press, San Diego 719-725 (2012) [B1]

Co-authors: Trevor Day

Journal article (43 outputs)

YearCitationAltmetricsLink
2014James MH, Campbell EJ, Walker FR, Smith DW, Richardson HN, Hodgson DM, Dayas CV, 'Exercise reverses the effects of early life stress on orexin cell reactivity in male but not female rats', Frontiers in Behavioral Neuroscience, 8 (2014) [C1]
2014Walker FR, James MH, Hickie IB, McGorry PD, 'Clinical staging: a necessary step in the development of improved animal models of mood disturbance?', Int J Neuropsychopharmacol, 17 491-495 (2014) [C1]
2014Kongsui R, Beynon SB, Johnson SJ, Mayhew J, Kuter P, Nilsson M, Walker FR, 'Chronic stress induces prolonged suppression of the P2X7 receptor within multiple regions of the hippocampus: A cumulative threshold spectra analysis', Brain, Behavior, and Immunity, (2014)
2014Hollins SL, Goldie BJ, Carroll AP, Mason EA, Walker FR, Eyles DW, Cairns MJ, 'Ontogeny of small RNA in the regulation of mammalian brain development.', BMC Genomics, 15 777 (2014)
2014Iseme RA, McEvoy M, Kelly B, Agnew L, Attia J, Walker FR, 'Autoantibodies and depression: evidence for a causal link?', Neurosci Biobehav Rev, 40 62-79 (2014)
2014Walker FR, Beynon SB, Jones KA, Zhao Z, Kongsui R, Cairns M, Nilsson M, 'Dynamic structural remodelling of microglia in health and disease: a review of the models, the signals and the mechanisms.', Brain Behav Immun, 37 1-14 (2014)
2014Walker FR, Jones KA, Patience MJ, Zhao Z, Nilsson M, 'Stress as necessary component of realistic recovery in animal models of experimental stroke', Journal of Cerebral Blood Flow and Metabolism, 34 208-214 (2014)
2014Hollins SL, Zavitsanou K, Walker FR, Cairns MJ, 'Alteration of imprinted Dlk1-Dio3 miRNA cluster expression in the entorhinal cortex induced by maternal immune activation and adolescent cannabinoid exposure.', Transl Psychiatry, 4 e452 (2014)
2013Hinwood M, Tynan RJ, Charnley JL, Beynon SB, Day TA, Walker FR, 'Chronic Stress Induced Remodeling of the Prefrontal Cortex: Structural Re-Organization of Microglia and the Inhibitory Effect of Minocycline', CEREBRAL CORTEX, 23 1784-1797 (2013) [C1]
2013Bobrovskaya L, Beard D, Bondarenko E, Beig MI, Jobling P, Walker FR, et al., 'Does exposure to chronic stress influence blood pressure in rats?', AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, 177 217-223 (2013) [C1]
2013Tynan RJ, Beynon SB, Hinwood M, Johnson SJ, Nilsson M, Woods JJ, Walker FR, 'Chronic stress-induced disruption of the astrocyte network is driven by structural atrophy and not loss of astrocytes', Acta Neuropathologica, 126 75-91 (2013) [C1]
2013Walker FR, Nilsson M, Jones K, 'Acute and Chronic Stress-Induced Disturbances of Microglial Plasticity, Phenotype and Function', Current Drug Targets, 14 1262-1276 (2013) [C1]
2013Walker FR, 'A critical review of the mechanism of action for the selective serotonin reuptake inhibitors: Do these drugs possess anti-inflammatory properties and how relevant is this in the treatment of depression?', NEUROPHARMACOLOGY, 67 304-317 (2013) [C1]
2012Barreto RDA, Walker FR, Dunkley PR, Day TA, Smith DW, 'Fluoxetine prevents development of an early stress-related molecular signature in the rat infralimbic medial prefrontal cortex. Implications for depression?', BMC Neuroscience, 13 1-12 (2012) [C1]
2012Hinwood M, Morandini J, Day TA, Walker FR, 'Evidence that microglia mediate the neurobiological effects of chronic psychological stress on the medial prefrontal cortex', Cerebral Cortex, 22 1442-1454 (2012) [C1]

Co-authors: Trevor Day

2012Tynan R, Weidenhofer JC, Hinwood M, Cairns MJ, Day TA, Walker FR, 'A comparative examination of the anti-inflammatory effects of SSRI and SNRI antidepressants on LPS stimulated microglia', Brain Behavior and Immunity, 26 469-479 (2012) [C1]
2012Sominsky Bar L, Walker AK, Ong LK, Tynan R, Walker FR, Hodgson DM, 'Increased microglial activation in the rat brain following neonatal exposure to a bacterial mimetic', Behavioural Brain Research, 226 351-356 (2012) [C1]
2012Beynon SB, Walker FR, 'Microglial activation in the injured and healthy brain: What are we really talking about? Practical and theoretical issues associated with the measurement of changes in microglial morphology', Neuroscience, 225 162-171 (2012) [C1]
2011Beig MI, Callister R, Saint DA, Bondarenko E, Walker FR, Day TA, Nalivaiko E, 'Voluntary exercise does not affect stress-induced tachycardia, but improves resistance to cardiac arrhythmias in rats', Clinical and Experimental Pharmacology and Physiology, 38 19-26 (2011) [C1]
2011Ong LK, Bobrovskaya L, Walker FR, Day TA, Dickson PW, Dunkley PR, 'The effect of social defeat on tyrosine hydroxylase phosphorylation in the rat brain and adrenal gland', Neurochemical Research, 36 27-33 (2011) [C1]
2011Hinwood M, Tynan R, Day TA, Walker FR, 'Repeated social defeat selectively increases DeltaFosB expression and histone H3 acetylation in the infralimbic medial prefrontal cortex', Cerebral Cortex, 21 262-271 (2011) [C1]
2011Carnevali L, Bondarenko E, Sgoifo A, Walker FR, Head GA, Lukoshkova EV, et al., 'Metyrapone and fluoxetine suppress enduring behavioral but not cardiac effects of subchronic stress in rats', American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 301 R1123-R1131 (2011) [C1]
2010Tynan R, Naicker S, Hinwood M, Nalivaiko E, Buller KM, Pow DV, et al., 'Chronic stress alters the density and morphology of microglia in a subset of stress-responsive brain regions', Brain Behavior and Immunity, 24 1058-1068 (2010) [C1]
2010Mackenzie LJ, Nalivaiko E, Beig MI, Day TA, Walker FR, 'Ability of predator odour exposure to elicit conditioned versus sensitised post traumatic stress disorder-like behaviours, and forebrain dFosB expression, in rats', Neuroscience, 169 733-742 (2010) [C1]
2010Hodyl NA, Walker FR, Krivanek K, Clifton VL, Hodgson DM, 'Prenatal endotoxin exposure alters behavioural pain responses to lipopolysaccharide in adult offspring', Physiology & Behavior, 100 143-147 (2010) [C1]
2010Kabir MM, Beig MI, Baumert M, Trombini M, Mastorci F, Sgoifo A, et al., 'Respiratory pattern in awake rats: Effects of motor activity and of alerting stimuli', Physiology and Behavior, 101 22-31 (2010) [C1]
2009Walker FR, Naicker S, Hinwood M, Dunn N, Day TA, 'Strain differences in coping behaviour, novelty seeking behaviour, and susceptibility to socially conditioned fear: A comparison between Wistar and Sprague Dawley rats', Stress: The International Journal on the Biology of Stress, 12 507-516 (2009) [C1]
2009Walker FR, Masters LM, Dielenberg R, Day TA, 'Coping with defeat: Acute glucocorticoid and forebrain responses to social defeat vary with defeat episode behaviour', Neuroscience, 162 244-253 (2009) [C1]
2009Walker FR, Hodyl NA, Hodgson DM, 'Neonatal bacterial endotoxin challenge interacts with stress in the adult male rat to modify KLH specific antibody production but not KLH stimulated ex vivo cytokine release', Journal of Neuroimmunology, 207 57-65 (2009) [C1]
2009Beig MI, Baumert M, Walker FR, Day TA, Nalivaiko E, 'Blockade of 5-HT2A receptors suppresses hyperthermic but not cardiovascular responses to psychosocial stress in rats', Neuroscience, 159 1185-1191 (2009) [C1]
2008Walker FR, Knott BG, Hodgson DM, 'Neonatal endotoxin exposure modifies the acoustic startle response and circulating levels of corticosterone in the adult rat but only following acute stress', Journal of Psychiatric Research, 42 1094-1103 (2008) [C1]
2008Walker FR, Hinwood M, Masters LM, Dielenberg R, Day TA, 'Individual differences predict susceptibility to conditioned fear arising from psychosocial trauma', Journal of Psychiatric Research, 42 371-383 (2008) [C1]
2007Hodyl NA, Walker FR, Krivanek K, Clifton VL, Hodgson DM, 'Modelling prenatal bacterial infection: Functional consequences of altered hypothalamic pituitary adrenal axis development', Behavioral Brain Research, 178 108-114 (2007) [C1]
2007Day TA, Walker FR, 'More appraisal please: A commentary on Pfaff et al. (2007) 'Relations between mechanisms of CNS arousal and mechanisms of stress'', Stress: The International Journal on the Biology of Stress, 10 311-313 (2007) [C1]
2006Walker FR, Owens J, Ali S, Hodgson DM, 'Individual differences in glucose homeostasis: Do our early life interactions with bacteria matter?', Brain Behavior and Immunity, 20 401-409 (2006) [C1]
2006Walker FR, Hodyl NA, Krivanek K, Hodgson DM, 'Early life host-bacteria relations and development: Long-term individual differences in neuroimmune function following neonatal endotoxin challenge', Physiology & Behavior, 87 126-134 (2006) [C1]
2004Walker FR, Brogan AE, Smith R, Hodgson DM, 'A profile of the immediate endocrine, metabolic and behavioural responses following a dual exposure to endotoxin in early life', Physiology & Behavior, 83 495-504 (2004) [C1]
2004Walker FR, March JR, Hodgson DM, 'Endotoxin exposure in early life alters the development of anxiety-like behaviour in the Fischer 344 rat', Behavioural Brain Research, 154 63-69 (2004) [C1]
2004Hodyl NA, Walker FR, Mears CEP, Hume KA, Hodgson DM, 'Prenatal exposure to endotoxin in the Fischer 344 rat: consequences for neuroendocrine and immune function, and nocieptive thresholds in the offspring', Brian, Behavior, and Immunity, 18 CD (2004) [C3]

Co-authors: Deborah Hodgson

2004Walker FR, Hodyl NA, Hodgson DM, 'The effect of postnatal endotoxin exposure on nociception in adulthood: hyper-analgesia following immune challenge', Brain, Behavior, and Immunity, 18 CD (2004) [C3]

Co-authors: Deborah Hodgson

2004Walker FR, Hodgson DM, 'Interactions between the newborn and the early life microbial environment alter the development of anxiety-like behaviour in the Fischer 344 Rat', Australian Journal of Psychology, 56 232 (2004) [C3]

Co-authors: Deborah Hodgson

2003Hodyl NA, Walker FR, Hodgson DM, 'Prenatal exposure to bacteria alters foetal hypothalamic-pituitary-adrenal development', Australian Journal of Psychology, 55 215 (2003) [C3]

Co-authors: Deborah Hodgson

2001Hodgson DM, Knott BG, Walker FR, 'Neonatal Endotoxin Exposure Influences HPA Responsivity and Impairs Tumour Immunity in Fischer 344 Rats in Adulthood', Pediatric Research, 50:6 750-755 (2001) [C1]

Co-authors: Deborah Hodgson

Show 40 more

Conference (39 outputs)

YearCitationAltmetricsLink
2013Tynan R, Beynon S, Nilsson M, Walker F, 'CHRONIC STRESS INDUCES PROFOUND STRUCTURAL REMODELLING OF ASTROCYTES WITHIN THEPREFRONTAL CORTEX: A CHARACTERIZATION OF THE RELATIONSHIP BETWEEN ASTROCYTE MORPHOLOGYAND DENSITY', GLIA, Berlin, GERMANY (2013) [E3]
2012Walker FR, Tynan R, Day TA, 'More than just reuptake inhibitors: A comparative examination of the antiinflammatory effects of SSRI and SNRI antidepressants on microglia', Abstracts. Australian Neuroscience Society 32nd Annual Meeting, Gold Coast, Queensland (2012) [E3]

Co-authors: Trevor Day

2012Walker FR, 'The role of microglia in the regulation of mood state and cognitive function', Abstracts of the 21st Annual Meeting of the International Behavioral Neuroscience Society, Kona, Hawaii (2012) [E3]
2012Walker FR, Tynan R, Hinwood M, Woodworth SB, 'The role of microglia in cognitive disturbance: A new frontier in the neurobiology of stress', Brain, Behavior, and Immunity, San Diego, CA (2012) [E3]
2011Nalivaiko E, Carnevali L, Bondarenko E, Sgoifo A, Walker FR, Day TA, 'Metyrapone and fluoxetine suppress behavioural but not cardiac effects of sub-chronic stress in rats', FASEB JOURNAL, Washington, DC (2011) [E3]
2011Bondarenko E, Carnevali L, McPherson AE, Walker FR, Day TA, Hodgson DM, Nalivaiko E, 'Respiratory, but not cardiac, responses to acoustic stimulation are attenuated by diazepam pre-treatment: A novel index of anxiety in rats', Oral abstracts. Australian Neuroscience Society Annual Meeting, Auckland, NZ (2011) [E3]
2011Walker FR, Tynan R, Day TA, Ng A, Hinwood M, 'What have microglia got to do with it? New directions in the neurobiology of depression', Brain, Behavior, and Immunity, Chicago, Illinois (2011) [E3]

Co-authors: Trevor Day

2011Tynan RJ, Day TA, Brichta AM, Walker FR, 'Not Just Reuptake. Selective serotonin reuptake inhibitors attenuate LPS induced microglial pro-inflammatory cytokine production', Society of Neuroscience, Washington, D.C. (2011) [E3]

Co-authors: Alan Brichta

2011Carnevali L, Bondarenko E, Sgoifo A, Walker FR, Day TA, Nalivaiko E, 'Fluoxetine and metyrapone block behavioural but not cardiac effects of subchronic stress', Oral abstracts. Australian Neuroscience Society Annual Meeting, Auckland, NZ (2011) [E3]
2011Sominsky Bar L, Walker AK, Ong LK, Tynan R, Walker FR, Hodgson DM, 'Epigenetic inheritance of anxiety-like behaviour in rats - Role of early life exposure to a bacterial mimetic', Journal of Developmental Origins of Health and Disease, Portland, Oregon (2011) [E3]
2011Barreto RDA, Walker FR, Dunkley PR, Day TA, Smith DW, 'Alteration of neurotrophic factor pathway gene expression in the rat infralimbic medial prefrontal cortex by subchronic restraint stress is reversed by fluoxetine', Posters. Australian Neuroscience Society 31st Annual Meeting, Auckland, New Zealand (2011) [E3]
2010Walker FR, 'The role of microglia in the regulation of mood state: Implications for depression', Proceedings of the Australasian Society for Psychiatric Research (ASPR) 2010 Conference, Sydney, NSW (2010) [E3]
2010Nalivaiko E, Beard D, Bondarenko E, Beig MI, Jobling P, Walker FR, et al., 'CHRONIC FOOTSHOCK STRESS CAUSES ENDURING CHANGES IN CIRCADIAN RHYTHMS, WITHOUT PROVOKING HYPERTENSION IN RATS', FASEB JOURNAL (2010) [E3]
2009Ong LK, Bobrovskaya L, Walker FR, Day TA, Dickson PW, Dunkley PR, 'The effect of social conflict on tyrosine hydroxylase phosphorylation in catecholamine-producing cells from sprague-dawley rats', Journal of Neurochemistry, Busan, Korea (2009) [E3]
2009Tynan R, Naicker S, Day TA, Walker FR, 'The impact of chronic restraint stress on regulating behavioural and glial changes in the adult rat', ANS 2009 Abstracts: Posters, Canberra, ACT (2009) [E3]

Co-authors: Trevor Day

2007Masters LM, Walker FR, Dielenberg R, Day TA, 'Psychosocial stress: individual differences in coping behaviour, hpa axis activation and limbic system activation patterns (Poster)', 7th IBRO 2007 World Congress of Neuroscience Program, Melbourne (2007) [E3]

Co-authors: Trevor Day

2007Walker FR, Hinwood M, Masters LM, Dielenberg R, Day TA, 'Individual differences predict susceptibility to conditioned fear arising from psychosocial trauma (Poster)', 7th IBRO 2007 World Congress of Neuroscience Program, Melbourne (2007) [E3]

Co-authors: Trevor Day

2007Hinwood M, Walker FR, Day TA, 'Characterisation of fosB response in rat forebrain following exposure to chronic social stress (Poster)', 7th IBRO 2007 World Congress of Neuroscience Program, Melbourne (2007) [E3]

Co-authors: Trevor Day

2006Walker FR, Masters LM, Dielenberg R, Day TA, 'Individual differences in coping strategy predict glucocorticoid responses to psychosocial stress', Proceedings of the Australian Neuroscience Society, Sydney, NSW (2006) [E3]

Co-authors: Trevor Day

2005Krivanek K, Hodyl NA, Walker FR, Hodgson DM, 'Maternal and Foetal Immune and Neuroendocrine Response to Type 1 and Type 2 Immune Stimuli', "Before and Beyond Birth" Perinatal Society of Australia and New Zealand 9th Annual Congress, Adelaide, Australia (2005) [E3]

Co-authors: Deborah Hodgson

2005Beck AK, Hodyl NA, Krivanek K, Knott BG, Walker FR, Hodgson DM, 'Impact of Neonatal Endotoxin Exposure on Nociception in the F344 Rat: A Developmental Perspective', Australian Neuroscience Society: Proceedings of the 25th Annual "Silver Jubilee" Meeting, Perth, Australia (2005) [E3]

Co-authors: Deborah Hodgson

2005Knott BG, Walker FR, Hodgson DM, 'Postnatal Bacterial Infection as a Predictor of Post Traumatic Stress Disorder: Physiological and Behavioural Correlates in the Rodent', Pediatric Research: Placenta and Intrauterine Growth, V58(5) suppl: Proceedings of 3rd International Congress on Developmental Origins of Health & Disease, Toronto, Canada (2005) [E3]

Co-authors: Deborah Hodgson

2005Hodyl NA, Krivanek K, Walker FR, Hodgson DM, 'Neuroendocrine, Immune and Nociceptive Responses in Offspring Exposed to an Immune Challenge Prenatally', "Before and Beyond Birth" Perinatal Society of Australia and New Zealand 9th Annual Congress, Adelaide, Australia (2005) [E3]

Co-authors: Deborah Hodgson

2005Hodyl NA, Krivanek K, Walker FR, Feltis BB, Hodgson DM, 'A Developmental Profile of the Effects of Prenatal Endotoxin Exposure on Neuroendocrine and Immune Function', Australian Neuroscience Society: Proceedings of the 25th Annual "Silver Jubilee" Meeting, Perth, Australia (2005) [E3]

Co-authors: Deborah Hodgson

2003Hodgson DM, Mears CEP, Walker FR, 'Impact of immune activation during pregnancy on offspring's endocrine and immune responses in adulthood', Brain, Behavior, and Immunity, Amelia Island, Florida (2003) [E3]

Co-authors: Deborah Hodgson

2003Hodgson DM, Mears CEP, Walker FR, 'Immune activation during pregnancy alters offspring's endocrine and immune responses in adulthood', Pediatric Research, Brighton, UK (2003) [E3]

Co-authors: Deborah Hodgson

2003Hodyl NA, Walker FR, Owens J, Hodgson DM, 'Exposure to a Bacterial Infection During Pregancy alters Fetal Development with Consequences for Glucose Metabolism', The Endocrine Society of Australia Proceedings 2003, Melbourne, Victoria (2003) [E3]

Co-authors: Deborah Hodgson

2003Walker FR, Brogan AE, Hodgson DM, 'Neonatal endotoxin exposure alters mother-pup interactions and is associated with anxiety-like behaviour in adulthood', Brain Behaviour, and Immunity, Amelia Island, Florida (2003) [E3]

Co-authors: Deborah Hodgson

2003Walker FR, Hodyl NA, Hodgson DM, 'Neonatal Bacterial Endotoxin Exposure Alters Glucose Metabolism, Leptin Production and Body Mass Index Across Development in the Fischer 344 Rat', The Endocrine Society of Australia Proceedings 2003, Melbourne, Victoria (2003) [E3]

Co-authors: Deborah Hodgson

2003Walker FR, Hodgson DM, 'Neonatal endotoxin exposure alters metabolic and immune responses in adulthood', Pediatric Research, Brighton, UK (2003) [E3]

Co-authors: Deborah Hodgson

2002Hodyl NA, Walker FR, Hodgson DM, 'Prenatal endotoxin exposure reduces stress response of pre-weaned guinea pigs in sex-specific manner', Conference Supplements : The Endocrine Society of Australia, Adelaide, South Australia (2002) [E3]

Co-authors: Deborah Hodgson

2002Walker FR, Hodgson DM, 'Neonatal Bacterial endotoxin exposure alters pro-inflammatory and febrile responses in adult rodents', The Endocrine Society of Australia, Adelaide, South Australia (2002) [E3]

Co-authors: Deborah Hodgson

2002Hodgson DM, Hodyl NA, Walker FR, 'Neuroendocrine programming of cancer: the role of pre natal and postnatal physiological stressors', Conference supplements: The Endocrine Society of Australia, Adelaide, Australia (2002) [E3]

Co-authors: Deborah Hodgson

2002Hodgson DM, Brown A, Walker FR, 'Exposure to bacterial endotoxin in early life alters immunological responsivity in adulthood', Brain, Behavior, and Immunity vol 16, no.2, April 2002, Wisconsin, USA (2002) [E3]

Co-authors: Deborah Hodgson

2002Hodgson DM, March JR, Walker FR, 'Neonatal Exposure to Bacterial Endotoxin is Associated with Increased Anxiety-Related Behavior and Altered Metabolic Responsivity in Adulthood', Brain, Behavior, and Immunity vol 16, no.2, April 2002, Wisconsin, USA (2002) [E3]

Co-authors: Deborah Hodgson

2001Hodgson DM, Knott BG, Walker FR, Allen T, 'Neonatal Stress Potentiates HPA Activity and Enhances Tumor Metastasis in Adult Rodents', The Endocrine Society of Australia: Proceedings 2001, Queensland (2001) [E3]

Co-authors: Deborah Hodgson

2000Hodgson DM, Rosengren SM, Walker FR, 'Neonatal stress exposure impairs wound healing and tumor immunity in the adult rat', Psychoneuroendocronology (2000) [E3]

Co-authors: Deborah Hodgson

2000Hodgson DM, Rosengren SM, Walker FR, 'Exposure to neonatal stress potentiates hypothalmic-pituitary-adrenal (HPA) responsivity and impairs tumor immunity and wound healing in the adult rat', International Journal of Behavioural Medicine (2000) [E3]

Co-authors: Deborah Hodgson

2000Hodgson DM, Rosengren SM, Walker FR, 'Neonatal stress potentiates hypothalmic-pituitary-adrenal (HPA) responsivity and impairs wound healing and tumor resistance in the adult rat', Brain Behavior and Immunity, Brisbane Australia (2000) [E3]

Co-authors: Deborah Hodgson

Show 36 more
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Grants and Funding

Summary

Number of grants19
Total funding$2,143,127

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2014 (3 grants)

Modelling schizophrenia-associated changes in mir-137 expression$567,044
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Associate Professor Murray Cairns, Doctor Frederick Walker
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$567,04420142017
GNo:G1300360

Microglia as primary drivers of stress-induced changes in neuronal connectivity$460,037
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Frederick Walker, Doctor Brett Graham
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$460,03720142016
GNo:G1300330

Investigating the neuroprotective effects of growth hormone$110,750
Funding Body: University of Gothenburg

Project Team
Doctor Frederick Walker, Professor Michael Nilsson, Professor Jorgen Isgaard
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$110,75020142016
GNo:G1301437

2013 (5 grants)

Functional characterisation of schizophrenia-associated neurodevelopmental dysfunction of miR-137$25,000
Funding Body: Hunter Medical Research Institute

Project Team
Conjoint Associate Professor Murray Cairns, Doctor Frederick Walker, Associate Professor Alan Brichta, Ms Natalie Beveridge
SchemeRole
Near MissInvestigator
Total AmountFunding StartFunding Finish
$25,00020132013
GNo:G1300801

Functional characterisation of schizophrenia-associated neurodevelopmental dysfunction of miR-137$25,000
Funding Body: University of Newcastle

Project Team
Conjoint Associate Professor Murray Cairns, Doctor Frederick Walker, Associate Professor Alan Brichta, Ms Natalie Beveridge
SchemeRole
Near Miss GrantInvestigator
Total AmountFunding StartFunding Finish
$25,00020132013
GNo:G1300468

Understanding the role of microglia in stress-induced changes in neuronal connectivity$20,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Frederick Walker
SchemeRole
Near MissChief Investigator
Total AmountFunding StartFunding Finish
$20,00020132013
GNo:G1300799

Understanding the role of microglia in stress-induced changes in neuronal connectivity$20,000
Funding Body: University of Newcastle

Project Team
Doctor Frederick Walker
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$20,00020132013
GNo:G1300486

microRNA and translation dynamics of synaptic plasticity$20,000
Funding Body: University of Newcastle

Project Team
Conjoint Associate Professor Murray Cairns, Associate Professor Alan Brichta, Doctor Frederick Walker
SchemeRole
Near Miss GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020132013
GNo:G1300463

2012 (1 grants)

2011 Emerging Research Leaders Program$15,000
Funding Body: University of Newcastle

Project Team
Doctor Frederick Walker
SchemeRole
Emerging Research Leaders ProgramChief Investigator
Total AmountFunding StartFunding Finish
$15,00020122012
GNo:G1200470

2011 (5 grants)

A new target for antidepressant treatment: microglia mediated neuroinflammation$346,980
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Frederick Walker
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$346,98020112013
GNo:G1000245

2007 Research Fellowship$108,316
Funding Body: University of Newcastle

Project Team
Doctor Frederick Walker
SchemeRole
Postdoctoral Research FellowshipChief Investigator
Total AmountFunding StartFunding Finish
$108,31620112012
GNo:G1000609

Establishing the effectiveness of anti-neuroinflammatory agents in the fight against depression$15,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Frederick Walker, Professor Trevor Day
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$15,00020112011
GNo:G1001007

IMPLEN NanoPhotometer pearl$10,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Associate Professor Murray Cairns, Associate Professor Paul Tooney, Associate Professor Alan Brichta, Emeritus Professor John Rostas, Emeritus Professor Patricia Michie, Conjoint Professor Keith Jones, Professor Ulli Schall, Associate Professor Phillip Dickson, Doctor Frederick Walker, Doctor Rick Thorne, Doctor Chris Dayas, Doctor Nikki Verrills, Doctor Janet Holt, Doctor Severine Roselli, Doctor Kathryn Skelding, Doctor Jude Weidenhofer, Associate Professor Liz Milward, Doctor Charles De Bock, Doctor Julie Merriman-Jones, Doctor Jing Qin Wu, Doctor Bing Liu, Mr Dan Johnstone, Ms Belinda Goldie, Ms Natalie Beveridge
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020112011
GNo:G1100030

Annual Psychoneuroimmunology Research Society Meeting, Hilton Indian Lakes Resort, Chicago, Illnois, 7 - 12 June 2011$2,000
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Doctor Frederick Walker
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,00020112011
GNo:G1100430

2010 (2 grants)

Targeting neuroinflammation to improve the efficacy of antidepressant drugs$50,000
Funding Body: BellBerry Limited

Project Team
Doctor Frederick Walker, Dr Kathryn Buller, Associate Professor Paul Tooney
SchemeRole
Near MissChief Investigator
Total AmountFunding StartFunding Finish
$50,00020102012
GNo:G0900219

ABI 7500 Real Time PCR System $34,000
Funding Body: NHMRC (National Health & Medical Research Council)

2008 (2 grants)

A novel approach to developing new treatments for anxiety: Identification of neural pathways underlying resistance and susceptibility to anxiety disorders.$25,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Frederick Walker
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$25,00020082008
GNo:G0188476

2007 Research Fellowship Project grant $15,000
Funding Body: University of Newcastle

Project Team
Doctor Frederick Walker
SchemeRole
Research FellowshipChief Investigator
Total AmountFunding StartFunding Finish
$15,00020082008
GNo:G0187128

2007 (1 grants)

New treatments for depression: Identification of neural pathways underlying resistance and susceptibility to depression$274,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Frederick Walker
SchemeRole
Training (Postdoctoral) Fellowships - Peter Doherty Biomedical Fellowship (Australia)Chief Investigator
Total AmountFunding StartFunding Finish
$274,00020072010
GNo:G0186786
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Research Supervision

Number of current supervisions14
Total current UoN Masters EFTSL0.5
Total current UoN PhD EFTSL5.35

For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20142016M Philosophy(Elec Engineering)Co-SupervisorThe Design and Construction of an Intrinsic Optical Signal Brain Imaging System Combined with a Virtual Reality Setup to Investigate the Effects of Stroke in Mice
20142018PhD (Anatomy)Principal SupervisorInvestigating the Role of Glia and Glial Communication in Recovery from Stroke
20142018PhD (Human Physiology)Co-SupervisorCooling the Skin While Maintaining Normal Core Temperature to Prevent Intracranial Pressure Elevation and Improve Outcome after Stroke
20142018PhD (Anatomy)Principal SupervisorExamining the Role of Stress in Modulating the Function of Glia
20142018PhD (Anatomy)Principal SupervisorExamining the Role of Stress, Glia and Cognitive Function
20132017PhD (Anatomy)Principal SupervisorThe Effect of Chronic Stress on Stroke Recovery
20132017PhD (Anatomy)Principal SupervisorEnvironmental Enrichment to Improve Outcome After Stroke - What are the Key Contributory Factors?
20132017PhD (Anatomy)Co-SupervisorCharacterizing Changes in the Orexin System in Models of Neuropsychiatric Disease
20132016PhD (Anatomy)Principal SupervisorAstrocytes and Recovery from Ischemic Stroke
20122016PhD (CommunityMed & ClinEpid)Co-SupervisorThe Role of Autoantibodies in the Development of Depression
20112015PhD (Human Physiology)Principal SupervisorInvestigating the Role of Microglia in Regulating Complex Behaviour
20112015PhD (Medical Biochemistry)Co-SupervisorThe Role of miRNA and Post-Transcriptional Gene Silencing in Mediating the Mammalian Brains Response to Environmental Stress During Development and Ageing
20072008Honours Psychology
University of Newcastle
Sole SupervisorIndividual differences in susceptibility to fear related pathology
20072010PHD Medical Science
University of Newcastle
Co-SupervisorRole of dopamine in the medial pre-frontal cortex

Past Supervision

YearProgramSupervisor TypeResearch Title
2014PhD (Anatomy)Principal SupervisorThe Impact of Stress on Glia: A Characterisation of the Chronic Stress-Induced Density and Morphological Alterations Observed in Astrocytes and Microglia
2013PhD (Anatomy)Principal SupervisorNeurobiological Alterations in the Rat Medial Prefrontal Cortex following Exposure to Chronic Psychological Stress
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Dr Frederick Walker

Work Phone(02) 4921 5012
Fax(02) 4921 5141
Email
PositionResearch Fellow
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine
The University of Newcastle, Australia
Focus AreaAnatomy
Office
MSB306 OR Level 3 EAST HMRI,
Medical Sciences,
Callaghan
University Drive
Callaghan NSW 2308
Australia
URL:www.newcastle.edu.au/profile/rohan-walker