Associate Professor Liz Milward

Associate Professor Liz Milward

Associate Professor

School of Biomedical Sciences and Pharmacy (Medical Genetics)

Career Summary

Biography

Research Expertise

Focus Area: Medical Genetics


Qualifications

  • PhD, University of Western Australia
  • Bachelor of Science, University of Western Australia

Keywords

  • Ageing-Related Disorders
  • Anaemias
  • Iron-Related Disorders
  • Medical Genetics
  • Neurodegenerative Disorders
  • Other Biomedical Sciences

Fields of Research

CodeDescriptionPercentage
110399Clinical Sciences not elsewhere classified40
110999Neurosciences not elsewhere classified30
060499Genetics not elsewhere classified30

Professional Experience

UON Appointment

DatesTitleOrganisation / Department
1/07/2014 - Associate ProfessorUniversity of Newcastle
School of Biomedical Sciences and Pharmacy
Australia

Membership

DatesTitleOrganisation / Department
Member - The Myelin ProjectThe Myelin Project
Australia
Member - Human Genetics Society of Australia National Conference Local Organising CommitteeHuman Genetics Society of Australia National Conference Local Organising Committee
Australia
Elected Member - University of Newcastle Academic SenateUniversity of Newcastle
Australia

Awards

Recipient

YearAward
1995Extraordinary Ability Alien O1 Visa award
Unknown
1992International Fogarty Fellowship
Unknown

Invitations

PhD Examiner

YearTitle / Rationale
2007PhD Thesis Roula Papadopoulos 1999
Organisation: University of Melbourne
Edit

Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (3 outputs)

YearCitationAltmetricsLink
2012Milward AE, Acikyol B, Bassett BL, Williams EJ, Graham R, Delima R, et al., 'Brain changes in iron loading disorders', Metal Ions in Neurological Systems, Springer-Verlag Wien, Heidelberg 17-29 (2012) [B1]
2005Milward AE, Roy TK, 'Genetic Regulation of the Matrix Metalloproteinases and Related Proteins', Matriz Metalloproteinases in the Central Nervous System, Imperial College Press, London, United Kingdom 19-66 (2005) [B1]
2005Parsons CH, Koolwijk I, Roy TK, Roy CA, Johnstone DM, Vos CMP, et al., 'Matrix Metalloproteinases and Related Proteins in Alzheimer's Disease, Parkinson's Disease and Other Neurodegenerative Disorders', Matrix Metalloproteinases in the Central Nervous System, Imperial College Press, London, United Kingdom 279-310 (2005) [B1]

Journal article (58 outputs)

YearCitationAltmetricsLink
2014Milward EA, Moscato P, Riveros C, Johnstone DM, 'Beyond Statistics: A New Combinatorial Approach to Identifying Biomarker Panels for the Early Detection and Diagnosis of Alzheimer's Disease', JOURNAL OF ALZHEIMERS DISEASE, 39 211-217 (2014) [C1]
DOI10.3233/JAD-131424Author URL
Co-authorsPablo Moscato
2014Mate K, Riveros C, Weidenhofer J, Goldie B, Scott J, Moscato P, et al., 'Strategies for Enhancing Communication between Students, Academics and Researchers participating in Large-Scale Undergraduate Research Projects', International Journal of Innovation in Science and Mathematics Education, 22 14-29 (2014) [C1]
Co-authorsPablo Moscato, Karen Mate, Judith Weidenhofer
2013Acikyol B, Graham RM, Trinder D, House MJ, Olynyk JK, Scott RJ, et al., 'Brain transcriptome perturbations in the transferrin receptor 2 mutant mouse support the case for brain changes in iron loading disorders, including effects relating to long-term depression and long-term potentiation', Neuroscience, 235 119-128 (2013) [C1]
DOI10.1016/j.neuroscience.2013.01.014
CitationsScopus - 1Web of Science - 1
Co-authorsRodney Scott
2013Mate K, Sim A, Weidenhofer J, Milward L, Scott J, 'Investigation of the human disease osteogenesis imperfecta: A research-based introduction to concepts and skills in biomolecular analysis', Biochemistry & Molecular Biology Education, 41 103-109 (2013) [C1]
DOI10.1002/bmb.20672Author URL
CitationsScopus - 1
Co-authorsKaren Mate, Judith Weidenhofer, Alistair Sim
2013Johnstone DM, Riveros C, Heidari M, Graham RM, Trinder D, Berretta R, et al., 'Evaluation of Different Normalization and Analysis Procedures for Illumina Gene Expression Microarray Data Involving Small Changes', Microarrays, 2 131-152 (2013) [C1]
Co-authorsRodney Scott, Pablo Moscato, Regina Berretta
2012Chalmers KA, Knuiman MW, Divitini ML, Bruce DG, Olynyk JK, Milward AE, 'Long-term mortality risks associated with mild anaemia in older persons: The Busselton health study', Age and Ageing, 41 759-764 (2012) [C1]
CitationsScopus - 3Web of Science - 2
Co-authorsKerry Chalmers
2012Delima RD, Riveros RC, Olynyk JK, Scott R, Moscato PA, Milward AE, et al., 'Brain transcriptome perturbations in the Hfe(-/-) mouse model of genetic iron loading', Brain Research, 1448 144-152 (2012) [C1]
CitationsScopus - 6Web of Science - 6
Co-authorsPablo Moscato, Rodney Scott
2012Milward AE, Daneshi N, Johnstone DM, 'Emerging real-time technologies in molecular medicine and the evolution of integrated 'pharmacomics' approaches to personalized medicine and drug discovery', Pharmacology and Therapeutics, 136 295-304 (2012) [C1]
DOI10.1016/j.pharmthera.2012.08.008
CitationsScopus - 2Web of Science - 1
2012Johnstone DM, Graham RM, Trinder D, Riveros RC, Olynyk JK, Scott R, et al., 'Changes in brain transcripts related to Alzheimer's disease in a model of HFE hemochromatosis are not consistent with increased Alzheimer's disease risk', Journal of Alzheimers Disease, 30 791-803 (2012) [C1]
CitationsScopus - 2Web of Science - 2
Co-authorsPablo Moscato, Rodney Scott
2012Johnstone DM, Milward AE, Berretta RE, Moscato PA, 'Multivariate protein signatures of pre-clinical Alzheimer's disease in the Alzheimer's disease meuroimaging initiative (ADNI) plasma proteome dataset', PLoS One, 7 e34341 (2012) [C1]
CitationsScopus - 23Web of Science - 18
Co-authorsPablo Moscato, Regina Berretta
2011Zhou J, Broe M, Huang Y, Anderson JP, Gai W-P, Milward AE, et al., 'Changes in the solubility and phosphorylation of alpha-synuclein over the course of Parkinson's disease', Acta Neuropathologica, 121 695-704 (2011) [C1]
DOI10.1007/s00401-011-0815-1
CitationsScopus - 20Web of Science - 24
2010Johnstone DM, Milward AE, 'Molecular genetic approaches to understanding the roles and regulation of iron in brain health and disease', Journal of Neurochemistry, 113 1387-1402 (2010) [C1]
DOI10.1111/j.1471-4159.2010.06697.x
CitationsScopus - 17Web of Science - 14
2010Johnstone DM, Milward AE, 'Genome-wide microarray analysis of brain gene expression in mice on a short-term high iron diet', Neurochemistry International, 56 856-863 (2010) [C1]
DOI10.1016/j.neuint.2010.03.015
CitationsScopus - 12Web of Science - 12
2010Graham RM, Chua ACG, Carter KW, Delima RD, Johnstone DM, Herbison CE, et al., 'Hepatic iron loading in mice increases cholesterol biosynthesis', Hepatology, 52 462-471 (2010) [C1]
DOI10.1002/hep.23712
CitationsScopus - 22Web of Science - 20
2010Yeap BB, Beilin J, Shi Z, Knuiman MW, Olynyk JK, Chubb SAP, et al., 'The C282Y polymorphism of the hereditary hemochromatosis gene is associated with increased sex hormone-binding globulin and normal testosterone levels in men', Journal of Endocrinological Investigation, 33 544-548 (2010) [C1]
DOI10.3275/6864
2010House MJ, Pierre TGS, Milward AE, Bruce DG, Olynyk JK, 'Relationship Between Brain R-2 and Liver and Serum Iron Concentrations in Elderly Men', Magnetic Resonance in Medicine, 63 275-281 (2010) [C1]
DOI10.1002/mrm.22263
CitationsScopus - 18Web of Science - 16
2010Milward AE, Bruce DG, Knuiman MW, Divitini ML, Cole M, Inderjeeth CA, et al., 'A cross-sectional community study of serum iron measures and cognitive status in older adults', Journal of Alzheimers Disease, 20 617-623 (2010) [C1]
DOI10.3233/JAD-2010-1402
CitationsScopus - 7Web of Science - 7
2009Shi Z, Johnstone DM, Talseth-Palmer B, Evans T-J, Spigelman AD, Groombridge C, et al., 'Haemochromatosis HFE gene polymorphisms as potential modifiers of hereditary nonpolyposis colorectal cancer risk and onset age', International Journal of Cancer, 125 78-83 (2009) [C1]
DOI10.1002/ijc.24304
Co-authorsRodney Scott, Bente Talseth-Palmer
2009Yeap BB, Beilin J, Shi Z, Knuiman MW, Olynyk JK, Bruce DG, Milward AE, 'Serum testosterone levels correlate with haemoglobin in middle-aged and older men', Internal Medicine Journal, 39 532-538 (2009) [C1]
DOI10.1111/j.1445-5994.2008.01789.x
CitationsScopus - 14Web of Science - 12
2008Ayonrinde OT, Milward AE, Chua ACG, Trinder D, Olynyk JK, 'Clinical perspectives on hereditary hemochromatosis', Critical Reviews in Clinical Laboratory Sciences, 45 451-484 (2008) [C1]
DOI10.1080/10408360802335716
CitationsScopus - 18Web of Science - 15
2008Milward AE, Baines SK, Knijiman MW, Bartholomew HC, Divitini ML, Ravine DG, et al., 'Noncitrus fruits as novel dietary environmental modifiers of iron stores in people with or without HFE gene mutations', Mayo Clinic Proceedings, 83 543-549 (2008) [C1]
DOI10.4065/83.5.543
CitationsScopus - 25Web of Science - 23
Co-authorsSurinder Baines
2008Milward AE, Kim KJ, Szklarczyk A, Nguyen T, Melli G, Nayak M, et al., 'Cleavage of myelin associated glycoprotein by matrix metalloproteinases', Journal of Neuroimmunology, 193 140-148 (2008) [C1]
DOI10.1016/j.jneuroim.2007.11.001
CitationsScopus - 26Web of Science - 24
2007Szklarczyk A, Stins M, Milward AE, Ryu H, Fitzsimmons C, Sullivan D, Conant K, 'Glial activation and matrix metalloproteinase release in cerebral malaria', Journal of Neurovirology, 13 2-10 (2007) [C1]
DOI10.1080/13550280701258084
CitationsWeb of Science - 16
2007Milward AE, Fitzsimmons C, Szklarczyk A, Conant K, 'The matrix metalloproteinases and CNS plasticity: An overview', Journal of Neuroimmunology, 187 9-19 (2007) [C1]
DOI10.1016/j.jneuroim.2007.04.010
CitationsScopus - 37Web of Science - 34
2007Milward AE, Johnstone DM, Trinder D, Ramm G, Olynyk J, 'The Nexus of iron and inflammation in hepcidin regulation: SMADs, STATs, and ECSIT', Hepatology, 45 253-256 (2007) [C1]
DOI10.1002/hep.21526
CitationsScopus - 9
2005Olynyk JK, Trinder D, Milward AE, 'Hereditary haemochromatosis: To screen or not to screen? (editorial)', Journal of Hepatology, 43 9-10 (2005) [C3]
CitationsScopus - 5Web of Science - 5
2005Broe M, Shepherd CE, Mann DMA, Milward AE, Gai W-P, Thiel E, Halliday GM, 'Insoluble alpha-Synuclein in Alzheimer's Disease without Lewy Body Formation', Neurotoxicity Research, 7 69-76 (2005) [C1]
DOI10.1007/BF03033777
CitationsWeb of Science - 9
2005Milward AE, Trinder D, Wilcox C, Britton RS, Ramm GA, Olynyk JK, 'Is HFE involved in increased hepcidin expression and hypoferremia in inflammation and anemia of chronic disease?', Hepatology, 41 936-938 (2005) [C1]
DOI10.1002/hep.20652
CitationsScopus - 4
2004Verdile G, Gnjec A, Miklossy J, Fonte J, Veurink G, Bates K, et al., 'Protein markers for Alzheimer disease in the frontal cortex and cerebellum', Neurology, 63 1385-1392 (2004) [C1]
DOI10.1212/01.WNL.0000141848.45315.A6
CitationsScopus - 15Web of Science - 14
2004Milward EA, 'Student input into gene patent law reform', Issues 2004, 67 27-30 (2004) [C2]
2002Conant K, Haughey N, Nath A, St Hillaire C, Gary DS, Pardo CA, et al., 'Matrix metalloproteinase-1 activates a pertussis toxin-sensitive signaling pathway that stimulates the release of matrix metalloproteinase-9', Journal of Neurochemistry, 82 885-893 (2002) [C1]
CitationsWeb of Science - 22
2001Broe M, Shepherd CE, Milward EA, Halliday GM, 'Relationship between DNA fragmentation, morphological changes and neuronal loss in Alzheimer''s disease and dementia with Lewy bodies', Acta Neuropathologica, 101 616-624 (2001) [C1]
2001Connor JR, Milward EA, Moalem S, Sampietro M, Boyer P, Percy ME, et al., 'Is hemochromatosis a risk factor for Alzheimer''s disease?', Journal of Alzheimer''s Disease, 3 471-477 (2001) [C1]
CitationsScopus - 59
Co-authorsRodney Scott
2000Milward E, Grayson D, Creasey H, Kyngdon B, Janu M, Brooks W, Broe GA, 'Clinical issues - Anaemia and dementia in community-dwelling Australian elderly', AUSTRALASIAN JOURNAL ON AGEING, 19 25-25 (2000)
Author URL
2000Milward E, Zhang SC, Zhao M, Lundberg C, Ge B, Goetz BD, Duncan ID, 'Enhanced proliferation and directed migration of oligodendroglial progenitors co-grafted with growth factor secreting cells', Glia, 32 264-270 (2000) [C1]
CitationsScopus - 19Web of Science - 17
2000Milward E, Grayson D, Creasey H, Kyngdon B, Janu M, Brooks W, Broe GA, 'Anaemia and dementia in community-dwelling Australian elderly', Australasian Journal of Ageing, 19 (2000) [C2]
2000Broe M, Shepherd CE, Milward EA, Halliday GM, 'Morphological features of DNA fragmentation in patients with movement disorders and dementia', European Journal of Neuroscience, 12 (2000) [C2]
1999Milward EA, Grayson DA, Creasey H, Janu MR, Brooks WS, Broe GA, 'Evidence for association of anaemia with vascular dementia', Neuroreport, 10 2377-2381 (1999) [C1]
CitationsScopus - 28Web of Science - 21
1999Kwok JBJ, Li Q-X, Hallupp M, Milward L, Whyte S, Schofield PR, 'Novel familial early-onset Alzheimer''s disease mutation (Leu723Pro) in amyloid precursor protein (APP) gene increases production of 42(43) amino acid isoform of amyloid-beta peptide.', Alzheimer''s Disease and Related Disorders, 69-79 (1999) [C1]
1997Milward EA, Lundberg CG, Ge B, Lipsitz D, Zhao M, Duncan ID, 'Isolation and transplantation of multipotential populations of epidermal growth factor responsive neural progenitor cells from the canine brain', Journal of Neuroscience Research, 50 862-871 (1997) [C1]
CitationsScopus - 58Web of Science - 55
1997Fannarraga M, Milward EA, 'Characterization of a putative novel type of oligodendrocyte in cultures from rat spinal cord.', European Journal of Neuroscience, 9 2213-2217 (1997) [C1]
CitationsWeb of Science - 6
1996Zhao M, Milward EA, Duncan ID, 'Migration and myelination by CG4 cells in brain after intraventricular transplant', Journal of Neurochemistry, 66 (1996) [C2]
1996Milward EA, Lundberg CG, Ge B, Lipsitz D, Duncan ID, 'EGF-responsive multipotential neural progenitor cells from normal and ''shaking'' pups.', Journal of Neurochemistry, 66 (1996) [C2]
1995Wilt SG, Milward E, Zhou JM, Nagasato K, Patton H, Rusten R, et al., 'In vitro evidence for a dual role of tumor necrosis factor-alpha in human immunodeficiency virus type 1 encephalopathy', Annals of Neurology, 37 381-394 (1995) [C1]
CitationsScopus - 123Web of Science - 139
1995Duncan ID, Milward EA, 'Glial cell transplants: experimental therapies of myelin diseases', Brain Pathology, 5 301-310 (1995) [C1]
CitationsScopus - 34Web of Science - 32
1994Gogate N, Verma L, Zhou JM, Milward E, Rusten R, O''Connor M, et al., 'Plasticity in the adult human oligodendrocyte lineage', Journal of Neuroscience, 14 4571-4587 (1994) [C1]
CitationsScopus - 90Web of Science - 92
1993Milward EA, Dottori M, Papadopoulos R, Moir RD, Fuller SJ, Beyreuther K, Masters CL, 'Neurotrophic and cytotoxic actions of amyloid protein precursor of Alzheimer''s disease.', Advances in the Biosciences, 87 349-350 (1993) [C2]
1992Moir RD, Martins RN, Bush AI, Small DH, Milward EA, Rumble BA, et al., 'Human brain beta A4 amyloid protein precursor of Alzheimer''s disease: purification and partial characterization', Journal of Neurochemistry, (1992) [C1]
CitationsScopus - 34Web of Science - 46
1992Milward EA, Papadopoulos R, Fuller SJ, Moir RD, Small D, Beyreuther K, Masters CL, 'The amyloid protein precursor of Alzheimer''s disease is a mediator of the effects of nerve growth factor on neurite outgrowth.', Neuron, 9 129-137 (1992) [C1]
CitationsScopus - 315Web of Science - 372
1992Milward EA, Dottori M, Papadopoulos R, Moir RD, Fuller SJ, Beyreuther K, Masters CL, 'Beta A4 amyloid protein precursor of Alzheimer''s disease: evidence for neurotrophic and cytotoxic actions.', Neurobiology of Aging, 13 (1992) [C2]
1991Small DH, Moir RD, Fuller SJ, Michaelson S, Bush AI, Li QX, et al., 'A protease activity associated with acetylcholinesterase releases the membrane-bound form of the amyloid protein precursor of Alzheimer''s disease', Biochemistry, 30 10795-10799 (1991) [C1]
CitationsScopus - 41Web of Science - 65
1991Milward EA, Papadopoulos R, Fuller S, Beyreuther K, Masters CL, 'Alzheimer''s disease amyloid precursor protein promotes neurite outgrowth in PC12 cells.', Journal of Neurochemistry, 57 (1991) [C2]
1990BUSH AI, MARTINS RN, RUMBLE B, MOIR R, FULLER S, MILWARD E, et al., 'THE AMYLOID PRECURSOR PROTEIN OF ALZHEIMERS-DISEASE IS RELEASED BY HUMAN PLATELETS', JOURNAL OF BIOLOGICAL CHEMISTRY, 265 15977-15983 (1990)
Author URL
CitationsWeb of Science - 242
1990Milward EA, Yeoh GC, 'Expression of alpha-fetoprotein by differentiating fetal rat hepatocytes in vitro.', European Journal of Cell Biology, 52 185-192 (1990) [C1]
CitationsScopus - 6Web of Science - 6
1990MASTERS CL, BUSH A, EVIN G, FULLER S, LI QX, MACKENZIE I, et al., 'THE BA4 AMYLOID PROTEIN AND ITS PRECURSORS AS BIOLOGICAL MARKERS FOR ALZHEIMERS-DISEASE', NEUROBIOLOGY OF AGING, 11 330-331 (1990)
DOI10.1016/0197-4580(90)90874-YAuthor URL
1990Milward E, Martins R, Rumble B, Moir R, Weidemann A, Beyreuther K, Masters CL, 'Expression of Alzheimer''s disease amyloid precursor protein during postnatal development of rat brain.', Neurobiology of Aging, 11 (1990) [C2]
1990Bush A, Martins R, Rumble B, Moir R, Fuller SJ, Milward E, et al., 'The amyloid precursor protein of Alzheimer''s disease is released by human platelets.', Neurobiology of Aging, 11 (1990) [C2]
CitationsScopus - 175
1989Cake MH, Ho KK, Shelly L, Milward E, Yeoh GC, 'Insulin antagonism of dexamethasone induction of tyrosine aminotransferase in cultured fetal hepatocytes. A correlation between enzyme activity, synthesis, level of messenger RNA and transcription.', European Journal of Biochemistry, 182 429-435 (1989) [C1]
CitationsWeb of Science - 20
Show 55 more journal articles

Conference (26 outputs)

YearCitationAltmetricsLink
2013Milward E, Heidari M, Acikyol B, Graham R, Chua A, Delima R, et al., 'IRON ACCUMULATION IN THE CHOROID PLEXUS AND OTHER BRAIN BARRIER COMPONENTS IN MOUSE MODELS OF HEMOCHROMATOSIS', AMERICAN JOURNAL OF HEMATOLOGY (2013) [E3]
Author URL
Co-authorsPablo Moscato
2013Heidari M, Johnstone D, Graham R, Martin K, Olynyk J, Trinder D, et al., 'DOES IRON HAVE CAUSAL ROLES IN NEURODEGENERATION WITH BRAIN IRON ACCUMULATION? - A NEW VIEW FROM A MOUSE MODEL OF HEMOCHROMATOSIS', AMERICAN JOURNAL OF HEMATOLOGY (2013) [E3]
Author URL
2013Graham R, Delima RD, Johnstone D, Milward EA, Olynyk JK, Trinder D, 'CHANGES IN GENE EXPRESSION OF CHOLESTEROL METABOLISM PATHWAYS IN MOUSE MODELS OF HAEMOCHROMATOSIS', AMERICAN JOURNAL OF HEMATOLOGY (2013) [E3]
Author URL
2011Johnstone DM, Acikyol B, Graham R, House M, Trinder D, Olynyk J, et al., 'Gene expression studies in four different mouse models support the case for brain perturbations in iron overload disorders', Program Book: Fourth Congress of the International BioIron Society (IBIS), Vancouver, Canada (2011) [E3]
Co-authorsPablo Moscato
2011Acikyol B, Johnstone DM, Trinder D, Cairns MJ, Milward AE, 'Gene expression changes relating to key brain functions and neuropsychiatric disorders in the TFR2 mutant mouse', Program Book: Fourth Congress of the International BioIron Society (IBIS), Vancouver, Canada (2011) [E3]
Co-authorsMurray Cairns
2011Milward AE, Hollins SL, Graham R, Trinder D, Van Balen M, Olynyk J, et al., 'Iron and the biogenesis of melanin and melanosomes in the retina', Program Book: Fourth Congress of the International BioIron Society (IBIS), Vancouver, Canada (2011) [E3]
Co-authorsMurray Cairns
2011Johnstone DM, Zandvakili S, Graham R, Trinder D, Scott R, Olynyk J, et al., 'Molecular changes relevant to motor neuron disease in the HFE-/- mouse model of hemochromatosis', Program Book: Fourth Congress of the International BioIron Society (IBIS), Vancouver, Canada (2011) [E3]
Co-authorsRodney Scott, Pablo Moscato
2011Graham RM, Chua ACG, Delima RD, Johnstone DM, Milward AE, Olynyk JK, Trinder D, 'Upregulation of genes involved in cholesterol sorting in the face of hepatic iron loading', Program Book: Fourth Congress of the International BioIron Society (IBIS), Vancouver, Canada (2011) [E3]
2009Graham RM, Chua ACG, Carter K, Delima RD, Johnstone DM, Herbison CE, et al., 'Alterations in iron status are associated with changes in the cholesterol biosynthesis pathway', 2009 International Biolron Society Meeting: Program Book, Porto, Portugal (2009) [E3]
2009Hollins SL, Johnstone DM, Graham R, Van Helden DF, Kerr KP, Laver DR, et al., 'Cardiac gene expression in mouse models of iron loading disorders', 2009 International Biolron Society Meeting: Program Book, Porto, Portugal (2009) [E3]
Co-authorsDerek Laver, Rodney Scott, Dirk Vanhelden, Karen Kerr
2009House M, St Pierre T, Milward AE, Bruce D, Olynyk J, 'Relationship between brain R2 and liver and serum iron concentrations in elderly men', 2009 International Biolron Society Meeting: Program Book, Porto, Portugal (2009) [E3]
DOI10.1002/mrm.22263
2009Johnstone DM, Graham R, Trinder D, Scott R, Olynyk J, Milward AE, 'Gene expression changes related to Alzheimer's disease and other neurodegenerative disorders in a hemochromatosis Hfe knockout mouse model', 2009 International Biolron Society Meeting: Program Book, Porto, Portugal (2009) [E3]
Co-authorsRodney Scott
2009Johnstone DM, Graham RM, Trinder D, Scott R, Olynyk J, Milward AE, 'Genome-wide microarray analysis of brain from a hemochromatosis Hfe knockout mouse model shows few changes in iron-related gene expression', 2009 International Biolron Society Meeting: Program Book, Porto, Portugal (2009) [E3]
Co-authorsRodney Scott
2009Johnstone DM, Ravetti MG, Riveros C, Moscato PA, Hersey P, Scott R, Milward AE, 'Genome-wide microarray analysis of melanoma reveals unexpected anomalies in iron-related gene expression', 2009 International Biolron Society Meeting: Program Book, Porto, Portugal (2009) [E3]
Co-authorsPablo Moscato, Rodney Scott
2009Milward AE, Bruce D, Cole M, Knuiman M, Divitini M, Bartholomew H, et al., 'Serum ferritin is not related to cognitive status: Results from a perspective community study of older Australians', 2009 International Biolron Society Meeting: Program Book, Porto, Portugal (2009) [E3]
2009Johnstone DM, Graham RM, Trinder D, Scott R, Olynyk J, Milward AE, 'Genome-wide brain gene expression changes related to Alzheimer's disease and other neurodegenerative disorders in mouse models of dietary iron overload and human haemochromatosis', ASMR National Scientific Conference 2009. Proceedings of The Australian Society for Medical Research, 48th National Scientific Conference, Hobart, TAS (2009) [E3]
Co-authorsRodney Scott
2009Fitzsimmons C, Johnstone DM, Conant K, Milward AE, 'Matrix metalloproteinase (MMP) - mediated cleavage of the low-density lipoprotein receptor-related protein (LRP)', ASMR XVII NSW Scientific Meeting: Programme and Abstracts, Sydney, NSW (2009) [E3]
2009Hollins SL, Johnstone DM, Van Helden DF, Kerr KP, Laver DR, Metelerkamp KM, et al., 'Cardiac gene expression in mouse models of iron loading', ASMR XVII NSW Scientific Meeting: Programme and Abstracts, Sydney, NSW (2009) [E3]
Co-authorsRodney Scott, Derek Laver, Dirk Vanhelden, Karen Kerr
2009Johnstone DM, Ravetti MG, Moscato PA, Hersey P, Scott R, Milward AE, 'Metabolic gene expression in advanced melanoma', ASMR XVII NSW Scientific Meeting: Programme and Abstracts, Sydney, NSW (2009) [E3]
Co-authorsPablo Moscato, Rodney Scott
2009Goldie BJ, Johnstone DM, Milward AE, 'Evaluation of bioinformatics tools for ontology analysis', ASMR XVII NSW Scientific Meeting: Programme and Abstracts, Sydney, NSW (2009) [E3]
2009Graham RM, Chua ACG, Carter K, Delima RD, Johnstone DM, Herbison CE, et al., 'Alterations in iron status are associated with changes in the cholesterol biosynthesis pathway', Proceedings of the 19th Annual Combined Biological Sciences Meeting: Programme and Abstracts, Perth, WA (2009) [E3]
2009Milward AE, Johnstone DM, Ravetti MG, Berretta RE, Hersey P, Scott R, Moscato PA, 'The relationship between Parkinson's disease and melanoma: Insights from microarray analysis of genome-wide gene expression changes in melanoma', ASMR National Scientific Conference 2009. Proceedings of The Australian Society for Medical Research, 48th National Scientific Conference, Hobart, TAS (2009) [E3]
Co-authorsRodney Scott, Regina Berretta, Pablo Moscato
2008Milward AE, Bruce D, Cole M, Kniuman M, Divitini M, Bartholomew H, et al., 'No relationship between serum ferritin and cognitive status in a prospective community study of older adults', Alzheimer's and Dementia, Chicago, IL (2008) [E3]
2008Fitzsimmons C, Johnstone DM, Conant K, Milward AE, 'Matrix metalloproteina-mediated cleavage of the low-density lipoprotein receptor-related protein to generate soluble species with neurodegenerative potential', Alzheimer's and Disease, Chicago, IL (2008) [E3]
2008Johnstone DM, Graham R, Trinder D, Scott R, Olynyk JK, Milward AE, 'Alterations in the expression of genes important in Alzheimer's disease (APP presenilin 1 tau) in the HFE knockout mouse model of the iron disorder hemochromatosis', Alzheimer's and Disease, Chicago, IL (2008) [E3]
Co-authorsRodney Scott
2008Johnstone DM, Riveros C, Moscato P, Milward EA, 'Effects of different normalisation and analysis procedures on illumina gene expression microarray data' (2008)
Author URL
Co-authorsPablo Moscato
Show 23 more conferences
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Grants and Funding

Summary

Number of grants19
Total funding$1,653,666

Click on a grant title below to expand the full details for that specific grant.


20151 grants / $20,000

Investigation of the progression of Alzheimers Disease: Identification of potential drivers of disease$20,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamDoctor Jay Horvat, Associate Professor Liz Milward, Professor Phil Hansbro, Dr Daniel Johnstone
SchemeProject Grant
RoleInvestigator
Funding Start2015
Funding Finish2015
GNoG1500589
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

20132 grants / $59,596

20121 grants / $1,500

Molecular and Functional Responses to Iron Dysregulation in the Heart$1,500

Funding body: National Heart Foundation of Australia

Funding bodyNational Heart Foundation of Australia
Project TeamBassett, Brianna, Associate Professor Liz Milward
SchemeSummer Scholarship
RoleLead
Funding Start2012
Funding Finish2012
GNoG1201015
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

20111 grants / $10,000

IMPLEN NanoPhotometer pearl$10,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamConjoint Associate Professor Murray Cairns, Associate Professor Paul Tooney, Professor Alan Brichta, Emeritus Professor John Rostas, Emeritus Professor Patricia Michie, Conjoint Professor Keith Jones, Professor Ulli Schall, Associate Professor Phillip Dickson, Doctor Frederick Walker, Doctor Rick Thorne, Doctor Chris Dayas, Doctor Nikki Verrills, Doctor Janet Holt, Doctor Severine Roselli, Doctor Kathryn Skelding, Doctor Jude Weidenhofer, Associate Professor Liz Milward, Doctor Charles De Bock, Doctor Julie Merriman-Jones, Doctor Jing Qin Wu, Doctor Bing Liu, Mr Dan Johnstone, Ms Belinda Goldie, Doctor Natalie Beveridge
SchemeEquipment Grant
RoleInvestigator
Funding Start2011
Funding Finish2011
GNoG1100030
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

20102 grants / $101,115

HMRI MRSP Infrastructure Grant (10-11) - Cardiovascular$76,117

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamAssociate Professor Derek Laver, Professor Dirk Van Helden, Associate Professor Eugene Nalivaiko, Associate Professor Liz Milward, Professor Robert Callister, Professor Manohar Garg, Conjoint Professor Tony Quail
SchemeNSW MRSP Infrastructure Grant
RoleInvestigator
Funding Start2010
Funding Finish2010
GNoG1100525
Type Of FundingOther Public Sector - State
Category2OPS
UONY

Identification of novel biomarkers for pre-clinical Alzheimer's disease$24,998

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamProfessor Pablo Moscato, Associate Professor Liz Milward, Doctor Martin Ravetti, Mr Dan Johnstone, Dr M Guillemin, Associate Professor Regina Berretta
SchemeProject Grant
RoleInvestigator
Funding Start2010
Funding Finish2010
GNoG0900149
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

20083 grants / $29,000

The effects of iron status on calcium handling systems in heart and brain$25,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamAssociate Professor Derek Laver, Associate Professor Liz Milward, Professor Dirk Van Helden, Professor Rodney Scott
SchemeProject Grant
RoleInvestigator
Funding Start2008
Funding Finish2008
GNoG0188463
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

International Conference on Alzheimer's Disease ICAD 2008, Chicago, 26/7/2008 - 31/7/2008$2,500

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor Liz Milward
SchemeTravel Grant
RoleLead
Funding Start2008
Funding Finish2008
GNoG0189220
Type Of FundingInternal
CategoryINTE
UONY

Changes in heart gene expression in mice with a genetic iron disorder$1,500

Funding body: National Heart Foundation of Australia

Funding bodyNational Heart Foundation of Australia
Project TeamAssociate Professor Liz Milward
SchemeSummer Scholarship
RoleLead
Funding Start2008
Funding Finish2008
GNoG0189532
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

20073 grants / $46,414

High speed/sensitivity CCD camera$30,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamProfessor Dirk Van Helden, Professor Eileen McLaughlin, Professor Gordon Burns, Doctor Rick Thorne, Dr Marcus Howlett, Doctor Mohammad Imtiaz, Professor Alan Brichta, Professor Robert Callister, Doctor Brett Graham, Associate Professor Derek Laver, Associate Professor Liz Milward, Doctor John Holdsworth
SchemeEquipment Grant
RoleInvestigator
Funding Start2007
Funding Finish2007
GNoG0188196
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

2007 Research Development Fellowship$8,224

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor Liz Milward
SchemeResearch Development Fellowship
RoleLead
Funding Start2007
Funding Finish2007
GNoG0188237
Type Of FundingInternal
CategoryINTE
UONY

Microarray analyses of genes important in iron regulation and related disorders$8,190

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor Liz Milward, Professor Rodney Scott
SchemePilot Grant
RoleLead
Funding Start2007
Funding Finish2007
GNoG0187902
Type Of FundingInternal
CategoryINTE
UONY

20063 grants / $1,184,915

Anaemia in older Australians$20,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor Liz Milward, Professor John Olynyk, Associate Professor Matthew Knuiman, Associate Professor David Bruce, Professor Joseph Hung, Professor Paola Ferrari
SchemeNear Miss Grant
RoleLead
Funding Start2006
Funding Finish2006
GNoG0186060
Type Of FundingInternal
CategoryINTE
UONY

20051 grants / $29,326

Scholarship - Matching - Semester 2, 2005$29,326

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor Liz Milward
SchemeMulti-Year Project Grant Scholarship
RoleLead
Funding Start2005
Funding Finish2005
GNoG0185744
Type Of FundingInternal
CategoryINTE
UONY

20041 grants / $15,000

Effects of relaxation training in anxiety levels in patients with Alzheimers$15,000

Funding body: Alzheimers Australia Research Foundation Limited

Funding bodyAlzheimers Australia Research Foundation Limited
Project TeamMs Cherie Roy, Associate Professor Liz Milward
SchemeDementia Research Grant
RoleInvestigator
Funding Start2004
Funding Finish2004
GNoG0183983
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

20031 grants / $156,800

Iron and cognition in older adults$156,800

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamAssociate Professor Liz Milward
SchemeProject Grant
RoleLead
Funding Start2003
Funding Finish2003
GNoG0182748
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY
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Research Supervision

Current Supervision

CommencedResearch Title / Program / Supervisor Type
2015Neuropathological Effects of Putative Modifiers of Alzheimer's Disease Risk and Progression: Investigation in Mouse Models
Health, Faculty of Health and Medicine
Principal Supervisor
2014The Effects of Iron Dysregulation on the Heart, Lungs and Reproductive System
Health, Faculty of Health and Medicine
Principal Supervisor
2014Effect of Iron loading on vision in a mouse model of haemochromatosis
Health, Faculty of Health and Medicine
Principal Supervisor
2014Investigating the Inter-Relationship between Iron Homeostasis and Infection in the Pathogenesis of Disease
Microbiology, Faculty of Health and Medicine
Co-Supervisor
2014Strategies for Introducing Personalised Healthcare and Pharmacogenomics into Community Pharmacies.
Pharmacy, Faculty of Health and Medicine
Principal Supervisor
2014Do Iron Abnormalities Exacerbate Alzheimer¿s Disease? Investigations in Novel Mouse Models
Health, Faculty of Health and Medicine
Principal Supervisor
2013The Feasibility and Value of Holistic Systems-Based Approaches to Personalised, Patient-Centred Healthcare in Modern Pharmacy
Health, Faculty of Health and Medicine
Principal Supervisor
2012Gene Expression in Brain of Hfe-/-xTfr2mut Mouse, A Model of Human Iron Overload
Health, Faculty of Health and Medicine
Principal Supervisor

Past Supervision

YearResearch Title / Program / Supervisor Type
2014Gene Expression in the Brain of Mutant Mouse Models of Human Iron Overload
Health, Faculty of Health and Medicine
Principal Supervisor
2012Cleavage of the Low-Density Lipoprotein-Receptor-Related Protein (LRP) by Matrix Metalloproteinases (MMPs) in a Neural Cell Model: Identification of Multiple Soluble LRP (sLRP) Cleavage Products
Health, Faculty of Health and Medicine
Sole Supervisor
2012Matrix Metalloproteinase-2 in Early Embryo Implantation in the Mouse
Human Biology, Faculty of Health and Medicine
Principal Supervisor
2011Microarray Studies of Genome-Wide Changes in Brain and Heart Gene Expression in Mouse Models of Iron Overload
Health, Faculty of Health and Medicine
Principal Supervisor
2009Genetic Variations in the Base Excision Repair Gene Mutyh and its Relationship with Two Common Malignancies
Health, Faculty of Health and Medicine
Co-Supervisor
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Associate Professor Liz Milward

Position

Associate Professor
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine

Focus area

Medical Genetics

Contact Details

Emailliz.milward@newcastle.edu.au
Phone(02) 4921 5167
Fax(02) 4921 7903

Office

RoomMS408
BuildingMedical Sciences
LocationCallaghan
University Drive
Callaghan, NSW 2308
Australia
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