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Staff Profile

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Career Summary

Qualifications

  • PhD, University of Western Australia
  • Bachelor of Science, University of Western Australia

Research

Research keywords

  • Ageing-Related Disorders
  • Anaemias
  • Iron-Related Disorders
  • Neurodegenerative Disorders

Research expertise

Focus Area: Medical Genetics

Fields of Research

CodeDescriptionPercentage
110300Clinical Sciences40
060499Genetics Not Elsewhere Classified30
110900Neurosciences30

Memberships

Body relevant to professional practice.

  • Member - University of Newcastle Academic Senate Elected Member

Committee/Associations (relevant to research).

  • Member - Human Genetics Society of Australia National Conference Local Organising Committee
  • Member - The Myelin Project

Awards

Award

1995Extraordinary Ability Alien O1 Visa award
US Government (United States)
Awarded by the US Government based on peer advisory opinion
1992International Fogarty Fellowship
United States National Institutes of Health (United States)

Invitations

PhD Thesis Roula Papadopoulos 1999
University of Melbourne, Australia (PHD Examiner.)
2007

Teaching

Teaching keywords

  • Medical Genetics
  • Other Biomedical Sciences
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Highlighted Publications

For publications that are currently unpublished or in-press, details are shown in italics.

YearCitationAltmetricsLink
2005Milward AE, Trinder D, Wilcox C, Britton RS, Ramm GA, Olynyk JK, 'Is HFE involved in increased hepcidin expression and hypoferremia in inflammation and anemia of chronic disease?', Hepatology, 41 936-938 (2005) [C1]
2005Broe M, Shepherd CE, Mann DMA, Milward AE, Gai W-P, Thiel E, Halliday GM, 'Insoluble alpha-Synuclein in Alzheimer's Disease without Lewy Body Formation', Neurotoxicity Research, 7 69-76 (2005) [C1]

Publications

For publications that are currently unpublished or in-press, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Chapter (3 outputs)

YearCitationAltmetricsLink
2012Milward AE, Acikyol B, Bassett BL, Williams EJ, Graham R, Delima R, et al., 'Brain changes in iron loading disorders', Metal Ions in Neurological Systems, Springer-Verlag Wien, Heidelberg 17-29 (2012) [B1]
2005Parsons CH, Koolwijk I, Roy TK, Roy CA, Johnstone DM, Vos CMP, et al., 'Matrix Metalloproteinases and Related Proteins in Alzheimer's Disease, Parkinson's Disease and Other Neurodegenerative Disorders', Matrix Metalloproteinases in the Central Nervous System, Imperial College Press, London, United Kingdom 279-310 (2005) [B1]
2005Milward AE, Roy TK, 'Genetic Regulation of the Matrix Metalloproteinases and Related Proteins', Matriz Metalloproteinases in the Central Nervous System, Imperial College Press, London, United Kingdom 19-66 (2005) [B1]

Journal article (58 outputs)

YearCitationAltmetricsLink
2014Milward EA, Moscato P, Riveros C, Johnstone DM, 'Beyond Statistics: A New Combinatorial Approach to Identifying Biomarker Panels for the Early Detection and Diagnosis of Alzheimer's Disease', JOURNAL OF ALZHEIMERS DISEASE, 39 211-217 (2014) [C1]
2013Acikyol B, Graham RM, Trinder D, House MJ, Olynyk JK, Scott RJ, et al., ' Brain transcriptome perturbations in the transferrin receptor 2 mutant mouse support the case for brain changes in iron loading disorders, including effects relating to long-term depression and long-term potentiation', Neuroscience, 235 119-128 (2013) [C1]
2013Johnstone DM, Riveros C, Heidari M, Graham RM, Trinder D, Berretta R, et al., 'Evaluation of Different Normalization and Analysis Procedures for Illumina Gene Expression Microarray Data Involving Small Changes', Microarrays, 2 131-152 (2013) [C1]
2013Mate K, Sim A, Weidenhofer J, Milward L, Scott J, 'Investigation of the human disease osteogenesis imperfecta: A research-based introduction to concepts and skills in biomolecular analysis', Biochemistry & Molecular Biology Education, 41 103-109 (2013) [C1]
2012Delima RD, Riveros RC, Olynyk JK, Scott R, Moscato PA, Milward AE, et al., 'Brain transcriptome perturbations in the Hfe(-/-) mouse model of genetic iron loading', Brain Research, 1448 144-152 (2012) [C1]
2012Johnstone DM, Graham RM, Trinder D, Riveros RC, Olynyk JK, Scott R, et al., 'Changes in brain transcripts related to Alzheimer's disease in a model of HFE hemochromatosis are not consistent with increased Alzheimer's disease risk', Journal of Alzheimers Disease, 30 791-803 (2012) [C1]
2012Milward AE, Daneshi N, Johnstone DM, 'Emerging real-time technologies in molecular medicine and the evolution of integrated 'pharmacomics' approaches to personalized medicine and drug discovery', Pharmacology and Therapeutics, 136 295-304 (2012) [C1]
2012Chalmers KA, Knuiman MW, Divitini ML, Bruce DG, Olynyk JK, Milward AE, 'Long-term mortality risks associated with mild anaemia in older persons: The Busselton health study', Age and Ageing, 41 759-764 (2012) [C1]

Co-authors: Kerry Chalmers

2012Johnstone DM, Milward AE, Berretta RE, Moscato PA, 'Multivariate protein signatures of pre-clinical Alzheimer's disease in the Alzheimer's disease meuroimaging initiative (ADNI) plasma proteome dataset', PLoS One, 7 e34341 (2012) [C1]
2011Zhou J, Broe M, Huang Y, Anderson JP, Gai W-P, Milward AE, et al., 'Changes in the solubility and phosphorylation of alpha-synuclein over the course of Parkinson's disease', Acta Neuropathologica, 121 695-704 (2011) [C1]
2010Johnstone DM, Milward AE, 'Molecular genetic approaches to understanding the roles and regulation of iron in brain health and disease', Journal of Neurochemistry, 113 1387-1402 (2010) [C1]
2010Graham RM, Chua ACG, Carter KW, Delima RD, Johnstone DM, Herbison CE, et al., 'Hepatic iron loading in mice increases cholesterol biosynthesis', Hepatology, 52 462-471 (2010) [C1]
2010House MJ, Pierre TGS, Milward AE, Bruce DG, Olynyk JK, 'Relationship Between Brain R-2 and Liver and Serum Iron Concentrations in Elderly Men', Magnetic Resonance in Medicine, 63 275-281 (2010) [C1]
2010Milward AE, Bruce DG, Knuiman MW, Divitini ML, Cole M, Inderjeeth CA, et al., 'A cross-sectional community study of serum iron measures and cognitive status in older adults', Journal of Alzheimers Disease, 20 617-623 (2010) [C1]
2010Johnstone DM, Milward AE, 'Genome-wide microarray analysis of brain gene expression in mice on a short-term high iron diet', Neurochemistry International, 56 856-863 (2010) [C1]
2010Yeap BB, Beilin J, Shi Z, Knuiman MW, Olynyk JK, Chubb SAP, et al., 'The C282Y polymorphism of the hereditary hemochromatosis gene is associated with increased sex hormone-binding globulin and normal testosterone levels in men', Journal of Endocrinological Investigation, 33 544-548 (2010) [C1]
2009Shi Z, Johnstone DM, Talseth-Palmer B, Evans T-J, Spigelman AD, Groombridge C, et al., 'Haemochromatosis HFE gene polymorphisms as potential modifiers of hereditary nonpolyposis colorectal cancer risk and onset age', International Journal of Cancer, 125 78-83 (2009) [C1]
2009Yeap BB, Beilin J, Shi Z, Knuiman MW, Olynyk JK, Bruce DG, Milward AE, 'Serum testosterone levels correlate with haemoglobin in middle-aged and older men', Internal Medicine Journal, 39 532-538 (2009) [C1]
2008Ayonrinde OT, Milward AE, Chua ACG, Trinder D, Olynyk JK, 'Clinical perspectives on hereditary hemochromatosis', Critical Reviews in Clinical Laboratory Sciences, 45 451-484 (2008) [C1]
2008Milward AE, Baines SK, Knijiman MW, Bartholomew HC, Divitini ML, Ravine DG, et al., 'Noncitrus fruits as novel dietary environmental modifiers of iron stores in people with or without HFE gene mutations', Mayo Clinic Proceedings, 83 543-549 (2008) [C1]
2008Milward AE, Kim KJ, Szklarczyk A, Nguyen T, Melli G, Nayak M, et al., 'Cleavage of myelin associated glycoprotein by matrix metalloproteinases', Journal of Neuroimmunology, 193 140-148 (2008) [C1]
2007Szklarczyk A, Stins M, Milward AE, Ryu H, Fitzsimmons C, Sullivan D, Conant K, 'Glial activation and matrix metalloproteinase release in cerebral malaria', Journal of Neurovirology, 13 2-10 (2007) [C1]
2007Milward AE, Johnstone DM, Trinder D, Ramm G, Olynyk J, 'The Nexus of iron and inflammation in hepcidin regulation: SMADs, STATs, and ECSIT', Hepatology, 45 253-256 (2007) [C1]
2007Milward AE, Fitzsimmons C, Szklarczyk A, Conant K, 'The matrix metalloproteinases and CNS plasticity: An overview', Journal of Neuroimmunology, 187 9-19 (2007) [C1]
2005Kairupan CF, Meldrum CJ, Crooks R, Milward EA, Spigelman AD, Burgess B, et al., 'Mutation analysis of the MYH gene in an Australian series of colorectal polyposis patients with or without germline APC mutations', International Journal of Cancer, 116 73-77 (2005) [C1]
2005Broe M, Shepherd CE, Mann DMA, Milward AE, Gai W-P, Thiel E, Halliday GM, 'Insoluble alpha-Synuclein in Alzheimer's Disease without Lewy Body Formation', Neurotoxicity Research, 7 69-76 (2005) [C1]
2005Milward AE, Trinder D, Wilcox C, Britton RS, Ramm GA, Olynyk JK, 'Is HFE involved in increased hepcidin expression and hypoferremia in inflammation and anemia of chronic disease?', Hepatology, 41 936-938 (2005) [C1]
2005Olynyk JK, Trinder D, Milward AE, 'Hereditary haemochromatosis: To screen or not to screen? (editorial)', Journal of Hepatology, 43 9-10 (2005) [C3]
2004Verdile G, Gnjec A, Miklossy J, Fonte J, Veurink G, Bates K, et al., 'Protein markers for Alzheimer disease in the frontal cortex and cerebellum', Neurology, 63 1385-1392 (2004) [C1]
2004Milward EA, 'Student input into gene patent law reform', Issues 2004, 67 27-30 (2004) [C2]
2002Conant K, Haughey N, Nath A, St Hillaire C, Gary DS, Pardo CA, et al., 'Matrix metalloproteinase-1 activates a pertussis toxin-sensitive signaling pathway that stimulates the release of matrix metalloproteinase-9', Journal of Neurochemistry, 82 885-893 (2002) [C1]
2001Broe M, Shepherd CE, Milward EA, Halliday GM, 'Relationship between DNA fragmentation, morphological changes and neuronal loss in Alzheimer''s disease and dementia with Lewy bodies', Acta Neuropathologica, 101 616-624 (2001) [C1]
2001Connor JR, Milward EA, Moalem S, Sampietro M, Boyer P, Percy ME, et al., 'Is hemochromatosis a risk factor for Alzheimer''s disease?', Journal of Alzheimer''s Disease, 3 471-477 (2001) [C1]

Co-authors: Rodney Scott

2000Milward E, Zhang SC, Zhao M, Lundberg C, Ge B, Goetz BD, Duncan ID, 'Enhanced proliferation and directed migration of oligodendroglial progenitors co-grafted with growth factor secreting cells', Glia, 32 264-270 (2000) [C1]
2000Milward E, Grayson D, Creasey H, Kyngdon B, Janu M, Brooks W, Broe GA, 'Anaemia and dementia in community-dwelling Australian elderly', Australasian Journal of Ageing, 19 (2000) [C2]
2000Broe M, Shepherd CE, Milward EA, Halliday GM, 'Morphological features of DNA fragmentation in patients with movement disorders and dementia', European Journal of Neuroscience, 12 (2000) [C2]
2000Milward E, Grayson D, Creasey H, Kyngdon B, Janu M, Brooks W, Broe GA, 'Clinical issues - Anaemia and dementia in community-dwelling Australian elderly', AUSTRALASIAN JOURNAL ON AGEING, 19 25-25 (2000)
1999Kwok JBJ, Li Q-X, Hallupp M, Milward L, Whyte S, Schofield PR, 'Novel familial early-onset Alzheimer''s disease mutation (Leu723Pro) in amyloid precursor protein (APP) gene increases production of 42(43) amino acid isoform of amyloid-beta peptide.', Alzheimer''s Disease and Related Disorders, 69-79 (1999) [C1]
1999Milward EA, Grayson DA, Creasey H, Janu MR, Brooks WS, Broe GA, 'Evidence for association of anaemia with vascular dementia', Neuroreport, 10 2377-2381 (1999) [C1]
1997Milward EA, Lundberg CG, Ge B, Lipsitz D, Zhao M, Duncan ID, 'Isolation and transplantation of multipotential populations of epidermal growth factor responsive neural progenitor cells from the canine brain', Journal of Neuroscience Research, 50 862-871 (1997) [C1]
1997Fannarraga M, Milward EA, 'Characterization of a putative novel type of oligodendrocyte in cultures from rat spinal cord.', European Journal of Neuroscience, 9 2213-2217 (1997) [C1]
1996Zhao M, Milward EA, Duncan ID, 'Migration and myelination by CG4 cells in brain after intraventricular transplant', Journal of Neurochemistry, 66 (1996) [C2]
1996Milward EA, Lundberg CG, Ge B, Lipsitz D, Duncan ID, 'EGF-responsive multipotential neural progenitor cells from normal and ''shaking'' pups.', Journal of Neurochemistry, 66 (1996) [C2]
1995Wilt SG, Milward E, Zhou JM, Nagasato K, Patton H, Rusten R, et al., 'In vitro evidence for a dual role of tumor necrosis factor-alpha in human immunodeficiency virus type 1 encephalopathy', Annals of Neurology, 37 381-394 (1995) [C1]
1995Duncan ID, Milward EA, 'Glial cell transplants: experimental therapies of myelin diseases', Brain Pathology, 5 301-310 (1995) [C1]
1994Gogate N, Verma L, Zhou JM, Milward E, Rusten R, O''Connor M, et al., 'Plasticity in the adult human oligodendrocyte lineage', Journal of Neuroscience, 14 4571-4587 (1994) [C1]
1993Milward EA, Dottori M, Papadopoulos R, Moir RD, Fuller SJ, Beyreuther K, Masters CL, 'Neurotrophic and cytotoxic actions of amyloid protein precursor of Alzheimer''s disease.', Advances in the Biosciences, 87 349-350 (1993) [C2]
1992Milward EA, Papadopoulos R, Fuller SJ, Moir RD, Small D, Beyreuther K, Masters CL, 'The amyloid protein precursor of Alzheimer''s disease is a mediator of the effects of nerve growth factor on neurite outgrowth.', Neuron, 9 129-137 (1992) [C1]
1992Moir RD, Martins RN, Bush AI, Small DH, Milward EA, Rumble BA, et al., 'Human brain beta A4 amyloid protein precursor of Alzheimer''s disease: purification and partial characterization', Journal of Neurochemistry, (1992) [C1]
1992Milward EA, Dottori M, Papadopoulos R, Moir RD, Fuller SJ, Beyreuther K, Masters CL, 'Beta A4 amyloid protein precursor of Alzheimer''s disease: evidence for neurotrophic and cytotoxic actions.', Neurobiology of Aging, 13 (1992) [C2]
1991Small DH, Moir RD, Fuller SJ, Michaelson S, Bush AI, Li QX, et al., 'A protease activity associated with acetylcholinesterase releases the membrane-bound form of the amyloid protein precursor of Alzheimer''s disease', Biochemistry, 30 10795-10799 (1991) [C1]
1991Milward EA, Papadopoulos R, Fuller S, Beyreuther K, Masters CL, 'Alzheimer''s disease amyloid precursor protein promotes neurite outgrowth in PC12 cells.', Journal of Neurochemistry, 57 (1991) [C2]
1990Milward EA, Yeoh GC, 'Expression of alpha-fetoprotein by differentiating fetal rat hepatocytes in vitro.', European Journal of Cell Biology, 52 185-192 (1990) [C1]
1990Milward E, Martins R, Rumble B, Moir R, Weidemann A, Beyreuther K, Masters CL, 'Expression of Alzheimer''s disease amyloid precursor protein during postnatal development of rat brain.', Neurobiology of Aging, 11 (1990) [C2]
1990Bush A, Martins R, Rumble B, Moir R, Fuller SJ, Milward E, et al., 'The amyloid precursor protein of Alzheimer''s disease is released by human platelets.', Neurobiology of Aging, 11 (1990) [C2]
1990MASTERS CL, BUSH A, EVIN G, FULLER S, LI QX, MACKENZIE I, et al., 'THE BA4 AMYLOID PROTEIN AND ITS PRECURSORS AS BIOLOGICAL MARKERS FOR ALZHEIMERS-DISEASE', NEUROBIOLOGY OF AGING, 11 330-331 (1990)
1990BUSH AI, MARTINS RN, RUMBLE B, MOIR R, FULLER S, MILWARD E, et al., 'THE AMYLOID PRECURSOR PROTEIN OF ALZHEIMERS-DISEASE IS RELEASED BY HUMAN PLATELETS', JOURNAL OF BIOLOGICAL CHEMISTRY, 265 15977-15983 (1990)
1989Cake MH, Ho KK, Shelly L, Milward E, Yeoh GC, 'Insulin antagonism of dexamethasone induction of tyrosine aminotransferase in cultured fetal hepatocytes. A correlation between enzyme activity, synthesis, level of messenger RNA and transcription.', European Journal of Biochemistry, 182 429-435 (1989) [C1]
Show 55 more

Conference (25 outputs)

YearCitationAltmetricsLink
2013Heidari M, Johnstone D, Graham R, Martin K, Olynyk J, Trinder D, et al., 'DOES IRON HAVE CAUSAL ROLES IN NEURODEGENERATION WITH BRAIN IRON ACCUMULATION? - A NEW VIEW FROM A MOUSE MODEL OF HEMOCHROMATOSIS', AMERICAN JOURNAL OF HEMATOLOGY (2013) [E3]
2013Milward E, Heidari M, Acikyol B, Graham R, Chua A, Delima R, et al., 'IRON ACCUMULATION IN THE CHOROID PLEXUS AND OTHER BRAIN BARRIER COMPONENTS IN MOUSE MODELS OF HEMOCHROMATOSIS', AMERICAN JOURNAL OF HEMATOLOGY (2013) [E3]
2013Graham R, Delima RD, Johnstone D, Milward EA, Olynyk JK, Trinder D, 'CHANGES IN GENE EXPRESSION OF CHOLESTEROL METABOLISM PATHWAYS IN MOUSE MODELS OF HAEMOCHROMATOSIS', AMERICAN JOURNAL OF HEMATOLOGY (2013) [E3]
2011Johnstone DM, Zandvakili S, Graham R, Trinder D, Scott R, Olynyk J, et al., 'Molecular changes relevant to motor neuron disease in the HFE-/- mouse model of hemochromatosis', Program Book: Fourth Congress of the International BioIron Society (IBIS), Vancouver, Canada (2011) [E3]
2011Acikyol B, Johnstone DM, Trinder D, Cairns MJ, Milward AE, 'Gene expression changes relating to key brain functions and neuropsychiatric disorders in the TFR2 mutant mouse', Program Book: Fourth Congress of the International BioIron Society (IBIS), Vancouver, Canada (2011) [E3]

Co-authors: Rodney Scott

2011Milward AE, Hollins SL, Graham R, Trinder D, Van Balen M, Olynyk J, et al., 'Iron and the biogenesis of melanin and melanosomes in the retina', Program Book: Fourth Congress of the International BioIron Society (IBIS), Vancouver, Canada (2011) [E3]
2011Johnstone DM, Acikyol B, Graham R, House M, Trinder D, Olynyk J, et al., 'Gene expression studies in four different mouse models support the case for brain perturbations in iron overload disorders', Program Book: Fourth Congress of the International BioIron Society (IBIS), Vancouver, Canada (2011) [E3]

Co-authors: Pablo Moscato

2011Graham RM, Chua ACG, Delima RD, Johnstone DM, Milward AE, Olynyk JK, Trinder D, 'Upregulation of genes involved in cholesterol sorting in the face of hepatic iron loading', Program Book: Fourth Congress of the International BioIron Society (IBIS), Vancouver, Canada (2011) [E3]
2009Goldie BJ, Johnstone DM, Milward AE, 'Evaluation of bioinformatics tools for ontology analysis', ASMR XVII NSW Scientific Meeting: Programme and Abstracts, Sydney, NSW (2009) [E3]
2009Milward AE, Bruce D, Cole M, Knuiman M, Divitini M, Bartholomew H, et al., 'Serum ferritin is not related to cognitive status: Results from a perspective community study of older Australians', 2009 International Biolron Society Meeting: Program Book, Porto, Portugal (2009) [E3]
2009Milward AE, Johnstone DM, Ravetti MG, Berretta RE, Hersey P, Scott R, Moscato PA, 'The relationship between Parkinson's disease and melanoma: Insights from microarray analysis of genome-wide gene expression changes in melanoma', ASMR National Scientific Conference 2009. Proceedings of The Australian Society for Medical Research, 48th National Scientific Conference, Hobart, TAS (2009) [E3]
2009Johnstone DM, Ravetti MG, Riveros C, Moscato PA, Hersey P, Scott R, Milward AE, 'Genome-wide microarray analysis of melanoma reveals unexpected anomalies in iron-related gene expression', 2009 International Biolron Society Meeting: Program Book, Porto, Portugal (2009) [E3]
2009Graham RM, Chua ACG, Carter K, Delima RD, Johnstone DM, Herbison CE, et al., 'Alterations in iron status are associated with changes in the cholesterol biosynthesis pathway', 2009 International Biolron Society Meeting: Program Book, Porto, Portugal (2009) [E3]
2009Johnstone DM, Graham RM, Trinder D, Scott R, Olynyk J, Milward AE, 'Genome-wide brain gene expression changes related to Alzheimer's disease and other neurodegenerative disorders in mouse models of dietary iron overload and human haemochromatosis', ASMR National Scientific Conference 2009. Proceedings of The Australian Society for Medical Research, 48th National Scientific Conference, Hobart, TAS (2009) [E3]

Co-authors: Rodney Scott

2009House M, St Pierre T, Milward AE, Bruce D, Olynyk J, 'Relationship between brain R2 and liver and serum iron concentrations in elderly men', 2009 International Biolron Society Meeting: Program Book, Porto, Portugal (2009) [E3]
2009Hollins SL, Johnstone DM, Van Helden DF, Kerr KP, Laver DR, Metelerkamp KM, et al., 'Cardiac gene expression in mouse models of iron loading', ASMR XVII NSW Scientific Meeting: Programme and Abstracts, Sydney, NSW (2009) [E3]
2009Johnstone DM, Ravetti MG, Moscato PA, Hersey P, Scott R, Milward AE, 'Metabolic gene expression in advanced melanoma', ASMR XVII NSW Scientific Meeting: Programme and Abstracts, Sydney, NSW (2009) [E3]
2009Graham RM, Chua ACG, Carter K, Delima RD, Johnstone DM, Herbison CE, et al., 'Alterations in iron status are associated with changes in the cholesterol biosynthesis pathway', Proceedings of the 19th Annual Combined Biological Sciences Meeting: Programme and Abstracts, Perth, WA (2009) [E3]
2009Fitzsimmons C, Johnstone DM, Conant K, Milward AE, 'Matrix metalloproteinase (MMP) - mediated cleavage of the low-density lipoprotein receptor-related protein (LRP)', ASMR XVII NSW Scientific Meeting: Programme and Abstracts, Sydney, NSW (2009) [E3]
2009Hollins SL, Johnstone DM, Graham R, Van Helden DF, Kerr KP, Laver DR, et al., 'Cardiac gene expression in mouse models of iron loading disorders', 2009 International Biolron Society Meeting: Program Book, Porto, Portugal (2009) [E3]
2009Johnstone DM, Graham RM, Trinder D, Scott R, Olynyk J, Milward AE, 'Genome-wide microarray analysis of brain from a hemochromatosis Hfe knockout mouse model shows few changes in iron-related gene expression', 2009 International Biolron Society Meeting: Program Book, Porto, Portugal (2009) [E3]

Co-authors: Rodney Scott

2009Johnstone DM, Graham R, Trinder D, Scott R, Olynyk J, Milward AE, 'Gene expression changes related to Alzheimer's disease and other neurodegenerative disorders in a hemochromatosis Hfe knockout mouse model', 2009 International Biolron Society Meeting: Program Book, Porto, Portugal (2009) [E3]

Co-authors: Rodney Scott

2008Johnstone DM, Graham R, Trinder D, Scott R, Olynyk JK, Milward AE, 'Alterations in the expression of genes important in Alzheimer's disease (APP presenilin 1 tau) in the HFE knockout mouse model of the iron disorder hemochromatosis', Alzheimer's and Disease, Chicago, IL (2008) [E3]

Co-authors: Rodney Scott

2008Milward AE, Bruce D, Cole M, Kniuman M, Divitini M, Bartholomew H, et al., 'No relationship between serum ferritin and cognitive status in a prospective community study of older adults', Alzheimer's and Dementia, Chicago, IL (2008) [E3]
2008Fitzsimmons C, Johnstone DM, Conant K, Milward AE, 'Matrix metalloproteina-mediated cleavage of the low-density lipoprotein receptor-related protein to generate soluble species with neurodegenerative potential', Alzheimer's and Disease, Chicago, IL (2008) [E3]
Show 22 more
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Grants and Funding

Summary

Number of grants18
Total funding$1,633,666

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2013 (2 grants)

Leica TP 1020 Automatic Tissue Processor for histology applications$35,000
Funding Body: NHMRC (National Health & Medical Research Council)

Ultra-Low Temperature Cryogenic Freezer$24,596
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Jude Weidenhofer, Doctor Rick Thorne, Doctor Kathryn Skelding, Doctor Nikki Verrills, Doctor Pradeep Tanwar, Associate Professor Phillip Dickson, Conjoint Associate Professor Murray Cairns, Professor Hubert Hondermarck, Professor Xu Dong Zhang, Associate Professor Estelle Sontag, Doctor Chen Chen Jiang, Associate Professor Liz Milward, Doctor Jean-Marie Sontag, Associate Professor Paul Tooney, Doctor Severine Roselli, Doctor Matt Dun, Doctor Chris Dayas, Doctor Lin Kooi Ong, Professor Dirk Van Helden, Mr Ben Copeland, Doctor Gabrielle Briggs, Emeritus Professor Leonie Ashman, Emeritus Professor John Rostas
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$24,59620132013
GNo:G1201189

2012 (1 grants)

Molecular and Functional Responses to Iron Dysregulation in the Heart$1,500
Funding Body: National Heart Foundation of Australia

Project Team
Bassett, Brianna, Associate Professor Liz Milward
SchemeRole
Summer ScholarshipChief Investigator
Total AmountFunding StartFunding Finish
$1,50020122012
GNo:G1201015

2011 (1 grants)

IMPLEN NanoPhotometer pearl$10,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Associate Professor Murray Cairns, Associate Professor Paul Tooney, Associate Professor Alan Brichta, Emeritus Professor John Rostas, Emeritus Professor Patricia Michie, Conjoint Professor Keith Jones, Professor Ulli Schall, Associate Professor Phillip Dickson, Doctor Frederick Walker, Doctor Rick Thorne, Doctor Chris Dayas, Doctor Nikki Verrills, Doctor Janet Holt, Doctor Severine Roselli, Doctor Kathryn Skelding, Doctor Jude Weidenhofer, Associate Professor Liz Milward, Doctor Charles De Bock, Doctor Julie Merriman-Jones, Doctor Jing Qin Wu, Doctor Bing Liu, Mr Dan Johnstone, Ms Belinda Goldie, Ms Natalie Beveridge
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020112011
GNo:G1100030

2010 (2 grants)

HMRI MRSP Infrastructure Grant (10-11) - Cardiovascular$76,117
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Derek Laver, Professor Dirk Van Helden, Associate Professor Eugene Nalivaiko, Associate Professor Liz Milward, Professor Robert Callister, Professor Manohar Garg, Conjoint Professor Tony Quail
SchemeRole
NSW MRSP Infrastructure GrantInvestigator
Total AmountFunding StartFunding Finish
$76,11720102010
GNo:G1100525

Identification of novel biomarkers for pre-clinical Alzheimer's disease$24,998
Funding Body: Hunter Medical Research Institute

Project Team
Professor Pablo Moscato, Associate Professor Liz Milward, Doctor Martin Ravetti, Mr Dan Johnstone, Dr M Guillemin, Associate Professor Regina Berretta
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$24,99820102010
GNo:G0900149

2008 (3 grants)

The effects of iron status on calcium handling systems in heart and brain$25,000
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Derek Laver, Associate Professor Liz Milward, Professor Dirk Van Helden, Professor Rodney Scott
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$25,00020082008
GNo:G0188463

International Conference on Alzheimer's Disease ICAD 2008, Chicago, 26/7/2008 - 31/7/2008$2,500
Funding Body: University of Newcastle

Project Team
Associate Professor Liz Milward
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,50020082008
GNo:G0189220

Changes in heart gene expression in mice with a genetic iron disorder$1,500
Funding Body: National Heart Foundation of Australia

Project Team
Associate Professor Liz Milward
SchemeRole
Summer ScholarshipChief Investigator
Total AmountFunding StartFunding Finish
$1,50020082009
GNo:G0189532

2007 (3 grants)

High speed/sensitivity CCD camera$30,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Dirk Van Helden, Professor Eileen McLaughlin, Professor Gordon Burns, Doctor Rick Thorne, Dr Marcus Howlett, Doctor Mohammad Imtiaz, Associate Professor Alan Brichta, Professor Robert Callister, Doctor Brett Graham, Associate Professor Derek Laver, Associate Professor Liz Milward, Doctor John Holdsworth
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$30,00020072007
GNo:G0188196

2007 Research Development Fellowship$8,224
Funding Body: University of Newcastle

Project Team
Associate Professor Liz Milward
SchemeRole
Research Development FellowshipChief Investigator
Total AmountFunding StartFunding Finish
$8,22420072007
GNo:G0188237

Microarray analyses of genes important in iron regulation and related disorders$8,190
Funding Body: University of Newcastle

Project Team
Associate Professor Liz Milward, Professor Rodney Scott
SchemeRole
Pilot GrantChief Investigator
Total AmountFunding StartFunding Finish
$8,19020072007
GNo:G0187902

2006 (3 grants)

PRC - Priority Research Centre for Bioinformatics, Biomarker Discovery & Information-Based Medicine (CIBM)$621,143
Funding Body: University of Newcastle

Project Team
Professor Pablo Moscato, Professor Rodney Scott, Emeritus Professor John Rostas, Professor John Forbes, Conjoint Professor Peter Hersey, Conjoint Professor Stephen Ackland, Conjoint Professor Wayne Smith, Emeritus Professor Peter Dunkley, Emeritus Professor Leonie Ashman, Professor John Attia, Associate Professor Phillip Dickson, Associate Professor Liz Milward, Professor Alistair Sim, Associate Professor Paul Tooney, Associate Professor Regina Berretta, Conjoint Professor David Sibbritt, Conjoint Professor Chris Levi, Professor Xu Dong Zhang, Conjoint Associate Professor Patricia Crock, Conjoint Associate Professor Jeannette Lechner-Scott
SchemeRole
Priority Research CentreInvestigator
Total AmountFunding StartFunding Finish
$621,14320062013
GNo:G0186919

PRC - Priority Research Centre for Gender health & Ageing$543,772
Funding Body: University of Newcastle

Project Team
Professor Julie Byles, Professor Sandra Capra, Associate Professor Pauline Chiarelli, Conjoint Professor David Henry, Professor Tina Koch, Ms Chris Landorf, Conjoint Professor Chris Levi, Associate Professor Deb Loxton, Associate Professor Liz Milward, Conjoint Associate Professor Lynne Parkinson, Professor Dimity Pond, Conjoint Professor David Sibbritt, Associate Professor Anne Young
SchemeRole
Priority Research CentreInvestigator
Total AmountFunding StartFunding Finish
$543,77220062013
GNo:G0186949

Anaemia in older Australians$20,000
Funding Body: University of Newcastle

Project Team
Associate Professor Liz Milward, Professor John Olynyk, Associate Professor Matthew Knuiman, Associate Professor David Bruce, Professor Joseph Hung, Professor Paola Ferrari
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$20,00020062006
GNo:G0186060

2005 (1 grants)

Scholarship - Matching - Semester 2, 2005$29,326
Funding Body: University of Newcastle

Project Team
Associate Professor Liz Milward
SchemeRole
Multi-Year Project Grant ScholarshipChief Investigator
Total AmountFunding StartFunding Finish
$29,32620052008
GNo:G0185744

2004 (1 grants)

Effects of relaxation training in anxiety levels in patients with Alzheimers$15,000
Funding Body: Alzheimers Australia Research Foundation Limited

Project Team
Ms Cherie Roy, Associate Professor Liz Milward
SchemeRole
Dementia Research GrantInvestigator
Total AmountFunding StartFunding Finish
$15,00020042004
GNo:G0183983

2003 (1 grants)

Iron and cognition in older adults$156,800
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Liz Milward
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$156,80020032005
GNo:G0182748
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Research Supervision

Number of current supervisions4
Total current UoN Masters EFTSL0.9
Total current UoN PhD EFTSL1.95

For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20142016M Philosophy (Medical Genetic)Principal SupervisorThe Effects of Iron Dysregulation on the Heart, Lungs and Reproductive System
20142018PhD (Medical Genetics)Principal SupervisorInvestigation of the effects of the common oxidant risk factors iron and smoking on the retina and the brain
20132018PhD (Medical Genetics)Principal SupervisorThe Feasibility and Value of Holistic Systems-Based Approaches to Personalised, Patient-Centred Healthcare in Modern Pharmacy
20122016PhD (Medical Genetics)Principal SupervisorGene Expression in Brain of Hfe-/-xTfr2mut Mouse, A Model of Human Iron Overload

Past Supervision

YearProgramSupervisor TypeResearch Title
2014M Philosophy (Medical Genetic)Principal SupervisorGene Expression in the Brain of Mutant Mouse Models of Human Iron Overload
2012PhD (Medical Genetics)Sole SupervisorCleavage of the Low-Density Lipoprotein-Receptor-Related Protein (LRP) by Matrix Metalloproteinases (MMPs) in a Neural Cell Model: Identification of Multiple Soluble LRP (sLRP) Cleavage Products
2012PhD (Anatomy)Principal SupervisorMatrix Metalloproteinase-2 in Early Embryo Implantation in the Mouse
2011PhD (Medical Genetics)Principal SupervisorMicroarray Studies of Genome-Wide Changes in Brain and Heart Gene Expression in Mouse Models of Iron Overload
2009PhD (Medical Genetics)Co-SupervisorGenetic Variations in the Base Excision Repair Gene Mutyh and its Relationship with Two Common Malignancies
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Associate Professor Adrienne (Liz) Milward

Work Phone(02) 4921 5167
Fax(02) 4921 7903
Email
PositionAssociate Professor
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine
The University of Newcastle, Australia
Focus AreaMedical Genetics
Office
MS408,
Medical Sciences,
Callaghan
University Drive
Callaghan NSW 2308
Australia
URL:www.newcastle.edu.au/profile/liz-milward
Linkhttp://www.newcastle.edu.au/school/biomedical-science/staff/LizMilward.html