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Dr Hayley Scott

Conjoint Fellow

School of Biomedical Sciences and Pharmacy

Career Summary

Biography

Dr Scott is a Conjoint Postdoctoral Research Fellow for the Priority Research Centre in Asthma and Respiratory Diseases, while she completes her postdoctoral studies at the Lung and Allergy Research Centre at the University of Queensland. Her research investigates the roles of obesity, exercise and nutrition in promoting or impeding inflammation and, ultimately, the effect this has on the pathogenesis of respiratory diseases including asthma and COPD.

She was the first internationally to demonstrate an inflammatory mechanism driving the association between obesity and asthma, and has also investigated whether weight loss (by dietary restriction and/or increasing exercise) is a potential treatment strategy for obese asthmatics. This study found that loss of fat tissue within the gynoid region is associated with a reduction to airway inflammation in females, while in males a reduced dietary intake of saturated fat was associated with a reduction to airway inflammation. This suggests that these changes are operating via different mechanisms in males versus females and, importantly, the obese-asthma association is responsive to dietary manipulation. Hayley has also investigated the potential therapeutic effects of exercise in asthma and found that a 10-week exercise training program resulted in a significant 5-fold reduction to airway inflammation and improved asthma-related quality of life. Her research was the first to establish that a 5-10% weight loss is associated with clinically important improvements to asthma control in 58% of patients and asthma-related quality of life in 83% of patients. Prior to this there was no specific weight loss target for obese asthmatics, and since its publication has been translated into practice as the target weight loss goal published in the “Asthma and Healthy Living” brochures by the National Asthma Council Australia, which is distributed to both general practitioners and patients nationally. More recently, Dr Scott has expanded her research into elucidating the role of exercise in reducing asthmatic airway inflammation and found that a one-off exercise session reduces inflammation in the airways, which has led her to commence an RCT as part of her postdoctoral studies aimed at elucidating whether exercise intensity impacts the response to exercise in those with asthma.

Dr Scott's qualification as a dietitian positions her uniquely within the field, as she is able to perform specialised dietary manipulations to achieve a desired clinical outcome. For example, she recently performed weight loss counselling in 30 adults with COPD, achieving an average weight loss of 10% in 3 months, maintenance of lean muscle mass and corresponding clinically important improvement in several disease outcomes linked with morbidity and mortality. She has also performed weight loss counselling in patients with asthma resulting in an average weight loss of 8% in 10 weeks, with significant improvements to asthma symptoms and asthma-related quality of life, as well as completed dietary manipulation of antioxidants, which modified patients risk of experiencing an asthma exacerbation. She has expertise in many specialised clinical techniques including venepuncture, hypertonic saline challenge and sputum collection, body composition and bone density analysis using dual-energy x-ray absorptiometry (DXA) and lung function testing, while her research utilises advanced laboratory techniques including measuring gene expression, and HPLC and GC for quantifying nutritional markers such as antioxidants and fatty acids. 

Research Expertise
Dr Scott is a Conjoint Postdoctoral Research Fellow for the Priority Research Centre in Asthma and Respiratory Diseases, while she is undertaking postdoctoral research at the Lung and Allergy Research Centre at the University of Queensland. Hayley completed her PhD in 2012, which sought to examine the mechanisms driving the association between obesity and asthma. This research was the first internationally to propose a plausible inflammatory mechanism driving the association between obesity and asthma. She then utilised her skills as a dietitian to design and undertake a randomised trial, where she examined the effects of weight loss in those with asthma to examine whether the detrimental effects of obesity in asthma could be reversed. This study was the first internationally to propose that a 5-10% weight loss was associated with clinically important improvements to asthma in most patients, and since its publication has been incorporated as a weight loss goal in the “Asthma and Healthy Living” brochures by the National Asthma Council Australia, which has been distributed to both general practitioners and patients nationally. Dr Scott's research has identified three common drivers of the obese-asthma phenotype, which her research focuses on: 1. Excess fat tissue: Dr Scott's research has shown that adiposity is associated with neutrophilic airway inflammation in those with asthma. When examined by sex, this relationship is only apparent in females, while weight loss reduces this inflammation in females. Neutrophilic airway inflammation is associated with the most severe forms of asthma and is not responsive to inhaled corticosteroid medications, the mainstay of asthma pharmacotherapy. Dr Scott is undertaking research to examine the hormonal drivers of this sex-specific effect with the hope of identifying alternate treatment options. 2. Exercise: Obesity is often associated with a low level of exercise. Dr Scott's research has shown that 10 weeks of exercise results in a five-fold reduction in eosinophilic airway inflammation, suggesting exercise is an important adjuvant asthma therapy and may be particularly useful for those who are refractory to current asthma therapies. Hayley is now conducting a randomised controlled trial aimed at elucidating how exercise intensity may have different inflammatory effects in those with asthma. 3. Dietary fat: Obesity is also often associated with a high dietary fat intake, with Dr Scott's research indicating that a high dietary fat intake is associated with increased neutrophilic airway inflammation in males with asthma, while restricting dietary fat intake is associated with a reduction in neutrophilic airway inflammation in males, suggesting reversibility of this phenomenon. The excellence of Dr Scott’s work has been recognised externally as she was awarded the Emerging Researcher for 2011 by the Nestle Nutrition Institute and Nutrition Society of Australia (NSA). More recently she was awarded the NSA Early Career Travel Grant, and has been awarded five conference travel awards since 2008. She was Chair of the Nutrition Society of Australia (Newcastle Branch) in 2012-2014, but in 2015 she stepped down to expand her postdoctoral research in Brisbane. Her research goal is to utilise her expertise in nutrition, weight loss counselling, exercise, body composition analysis and respiratory disease to ensure we gain a better understanding of the independent roles of obesity, exercise and dietary factors in driving respiratory disease outcomes, to enable optimisation of the clinical management of this population.


Qualifications

  • PhD, University of Newcastle
  • Bachelor of Nutrition and Dietetics (Honours), University of Newcastle

Keywords

  • Asthma
  • Fatty acids
  • Inflammation
  • Nutrition
  • Obesity
  • Respiratory Disease

Fields of Research

CodeDescriptionPercentage
110199Medical Biochemistry and Metabolomics not elsewhere classified50
110203Respiratory Diseases50

Professional Experience

UON Appointment

DatesTitleOrganisation / Department
6/06/2014 - 30/06/2014Research AssociateUniversity of Newcastle
School of Biomedical Sciences and Pharmacy
Australia
5/07/2013 - 30/09/2013Research AssociateUniversity of Newcastle
School of Nursing and Midwifery
Australia
20/02/2013 - 19/04/2013Clinical Trial OfficerUniversity of Newcastle
School of Medicine and Public Health
Australia
11/05/2012 - 31/12/2012Research AssociateUniversity of Newcastle
School of Medicine and Public Health
Australia
30/03/2012 - 20/12/2012Research AssociateUniversity of Newcastle
School of Education
Australia
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (1 outputs)

YearCitationAltmetricsLink
2013Scott H, Wood LG, Garg ML, Gibson PG, 'Asthma and Inflammation', Nutrition and Physical activity in inflammatory diseases, CABI, Oxford, UK 299-321 (2013) [B1]
Co-authorsManohar Garg, Lisa Wood, Peter Gibson

Journal article (14 outputs)

YearCitationAltmetricsLink
2015Periyalil HA, Wood LG, Scott HA, Jensen ME, Gibson PG, 'Macrophage activation, age and sex effects of immunometabolism in obese asthma', EUROPEAN RESPIRATORY JOURNAL, 45 388-395 (2015)
DOI10.1183/09031936.00080514Author URL
Co-authorsPeter Gibson, Lisa Wood
2015Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Determinants of weight loss success utilizing a meal replacement plan and/or exercise, in overweight and obese adults with asthma.', Respirology, 20 243-250 (2015)
DOI10.1111/resp.12423Author URL
CitationsScopus - 1Web of Science - 1
Co-authorsManohar Garg, Peter Gibson, Robin Callister, Philip Morgan, Lisa Wood
2015Scott HA, Latham JR, Callister R, Pretto JJ, Baines K, Saltos N, et al., 'Acute exercise is associated with reduced exhaled nitric oxide in physically inactive adults with asthma', Annals of Allergy, Asthma and Immunology, 114 470-479 (2015)

Background Although exercise has multiple health benefits, relatively little attention has been paid to its potential therapeutic effects in those with asthma. Objective To examine the effects of acute exercise on inflammation in physically inactive and active adults with asthma. Methods Fourteen adults with asthma (n = 6 physically inactive, n = 8 physically active) completed (1) 30 minutes of moderate-intensity exercise on a treadmill and (2) 30 minutes of rest in random order, with 4 weeks between sessions. Exhaled nitric oxide (eNO) was measured before and after the intervention (0, 0.5, 1, 2, 4, and 24 hours). Blood inflammatory mediators were measured before and after the intervention (0, 2, and 24 hours). Results Physically inactive participants had a significant decrease in eNO 4 hours after exercise (-4.8 ppb, -6.4 to -0.5 ppb, P =.028), which was not observed in physically active participants (P =.362). Interluekin-1 receptor antagonist increased in the physically inactive group 2 hours after exercise, with this increase strongly correlated with the decrease in eNO at 4 hours (R = -0.685, P =.007) and 24 hours (R = -0.659, P =.014) after exercise. Interleukin-6 was increased significantly 2 hours after exercise in physically inactive participants. Blood neutrophils and nuclear factor erythroid 2-like 2 gene expression were increased 2 hours after exercise in the overall cohort. Conclusion This study demonstrates that acute moderate-intensity exercise is associated with decreased eNO in physically inactive adults with asthma and suggests that interluekin-1 receptor antagonist could have a role in mediating this effect. The attenuated response in physically active participants might be due to the sustained anti-inflammatory effects of exercise training. Future studies should investigate the impact of exercise intensity and exercise training on airway inflammation in those with asthma.

DOI10.1016/j.anai.2015.04.002
Co-authorsLisa Wood, Robin Callister
2015Scott HA, Latham JR, Callister R, Pretto JJ, Baines K, Saltos N, et al., 'Acute exercise is associated with reduced exhaled nitric oxide in physically inactive adults with asthma', Annals of Allergy, Asthma and Immunology, (2015)

Background: Although exercise has multiple health benefits, relatively little attention has been paid to its potential therapeutic effects in those with asthma. Objective: To examine the effects of acute exercise on inflammation in physically inactive and active adults with asthma. Methods: Fourteen adults with asthma (n= 6 physically inactive, n= 8 physically active) completed (1) 30 minutes of moderate-intensity exercise on a treadmill and (2) 30 minutes of rest in random order, with 4 weeks between sessions. Exhaled nitric oxide (eNO) was measured before and after the intervention (0, 0.5, 1, 2, 4, and 24 hours). Blood inflammatory mediators were measured before and after the intervention (0, 2, and 24 hours). Results: Physically inactive participants had a significant decrease in eNO 4 hours after exercise (-4.8 ppb,-6.4 to-0.5 ppb, P= .028), which was not observed in physically active participants (P= .362). Interluekin-1 receptor antagonist increased in the physically inactive group 2 hours after exercise, with this increase strongly correlated with the decrease in eNO at 4 hours (R=-0.685, P= .007) and 24 hours (R=-0.659, P=.014) after exercise. Interleukin-6 was increased significantly 2 hours after exercise in physically inactive participants. Blood neutrophils and nuclear factor erythroid 2-like 2 gene expression were increased 2hours after exercise in the overall cohort. Conclusion: This study demonstrates that acute moderate-intensity exercise is associated with decreased eNO in physically inactive adults with asthma and suggests that interluekin-1 receptor antagonist could have a role in mediating this effect. The attenuated response in physically active participants might be due to the sustained anti-inflammatory effects of exercise training. Future studies should investigate the impact of exercise intensity and exercise training on airway inflammation in those with asthma. Trial registration: Australian New Zealand Clinical Trials Registry (http://www.anzctr.org.au), registration number ACTRN12613001014741.

DOI10.1016/j.anai.2015.04.002
Co-authorsLisa Wood, Katherine Baines, Robin Callister
2014Scott HA, Jensen ME, Wood LG, 'Dietary interventions in asthma', Current Pharmaceutical Design, 20 1003-1010 (2014) [C1]

Asthma is a chronic inflammatory disorder of the airways. The inflammatory response in asthma is heterogeneous. Allergen specific responses lead to activation of the acquired immune system, via a predominantly IL-5 mediated, eosinophilic pathway. Stimuli such as viruses and bacteria activate the innate immune system, via a predominantly IL-8 mediated, neutrophilic pathway. Asthma has also been demonstrated to involve a systemic inflammatory component. Glucocorticoids are the predominant pharmacological treatment used to control inflammation in asthma. However, compliance with medications can be compromised due to patient concerns about side effects. Hence dietary interventions that target the inflammatory response in asthma have great potential. Various aspects of dietary intake are known to modulate inflammation. Saturated fatty acids can induce an inflammatory response via activation of pattern recognition receptors. Omega-3 fatty acids can be anti-inflammatory, via mechanisms such as modification of eicosanoid production. Antioxidants can have anti-inflammatory effects as they scavenge free radicals, preventing activation of transcription factors including NF-¿B. Chronic excess energy intake can lead to obesity, which augments inflammation due to the release of inflammatory mediators by adipose tissue. Here we review the role of these dietary components in asthma. © 2014 Bentham Science Publishers.

DOI10.2174/13816128113190990421
CitationsScopus - 4Web of Science - 5
Co-authorsLisa Wood
2014Morgan PJ, Scott HA, Young MD, Plotnikoff RC, Collins CE, Callister R, 'Associations between program outcomes and adherence to Social Cognitive Theory tasks: process evaluation of the SHED-IT community weight loss trial for men', INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY, 11 (2014) [C1]
DOI10.1186/s12966-014-0089-9Author URL
CitationsWeb of Science - 3
Co-authorsRobin Callister, Myles Young, Ron Plotnikoff, Clare Collins, Philip Morgan
2013Morgan PJ, Barnett LM, Cliff DP, Okely AD, Scott HA, Cohen KE, Lubans DR, 'Fundamental movement skill interventions in youth: A systematic review and meta-analysis', Pediatrics, 132 (2013) [C1]
DOI10.1542/peds.2013-1167
CitationsScopus - 10Web of Science - 9
Co-authorsDavid Lubans, Philip Morgan
2013Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Dietary restriction and exercise improve airway inflammation and clinical outcomes in overweight and obese asthma: a randomized trial', Clinical and Experimental Allergy, 43 36-49 (2013) [C1]
DOI10.1111/cea.12004Author URL
CitationsScopus - 24Web of Science - 21
Co-authorsLisa Wood, Peter Gibson, Manohar Garg, Robin Callister, Philip Morgan
2012Wood LG, Garg ML, Smart JM, Scott HA, Barker D, Gibson PG, 'Manipulating antioxidant intake in asthma: A randomized controlled trial', American Journal of Clinical Nutrition, 96 534-543 (2012) [C1]
CitationsScopus - 26Web of Science - 26
Co-authorsLisa Wood, Peter Gibson, Manohar Garg
2012Wood LG, Baines KJ, Fu J, Scott HA, Gibson PG, 'The neutrophilic inflammatory phenotype is associated with systemic inflammation in asthma', Chest, 142 86-93 (2012) [C1]
CitationsScopus - 46Web of Science - 43
Co-authorsPeter Gibson, Lisa Wood, Katherine Baines
2012Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Relationship between body composition, inflammation and lung function in overweight and obese asthma', Respiratory Research, 13 1-10 (2012) [C1]
CitationsScopus - 10Web of Science - 8
Co-authorsPhilip Morgan, Robin Callister, Manohar Garg, Lisa Wood, Peter Gibson
2011Scott HA, Gibson PG, Garg ML, Wood LG, 'Airway inflammation is augmented by obesity and fatty acids in asthma', European Respiratory Journal, 38 594-602 (2011) [C1]
CitationsScopus - 67Web of Science - 62
Co-authorsManohar Garg, Lisa Wood, Peter Gibson
2009Wood LG, Scott HA, Garg ML, Gibson PG, 'Innate immune mechanisms linking non-esterified fatty acids and respiratory disease', Progress in Lipid Research, 48 27-43 (2009) [C1]
DOI10.1016/j.plipres.2008.10.001
CitationsScopus - 23Web of Science - 18
Co-authorsManohar Garg, Lisa Wood, Peter Gibson
2009McFarlane J, Scott HA, Robertson VJ, Gleeson C, Vanderkroft D, Wilson K, 'General practitioner and paediatrician self-reported capacity for the diagnosis and management of childhood and adolescent overweight and obesity', Nutrition & Dietetics, 66 176-185 (2009) [C1]
DOI10.1111/j.1747-0080.2009.01363.x
Show 11 more journal articles

Conference (26 outputs)

YearCitationAltmetricsLink
2014Periyalil H, Scott H, Jensen M, Wood L, Gibson P, 'MACROPHAGE ACTIVATION IS A DETERMINANT OF DEVELOPMENTAL EFFECTS OF IMMUNOMETABOLISM IN OBESE ASTHMA', RESPIROLOGY (2014) [E3]
DOI10.1111/resp.12263_7Author URL
Co-authorsLisa Wood, Peter Gibson
2014Mcdonald V, Gibson P, Scott H, Baines P, Hensley M, Pretto J, Wood L, 'SHOULD WE TREAT OBESITY IN COPD? THE EFFECTS OF WEIGHT LOSS AND RESISTANCE TRAINING IN OBESE COPD', RESPIROLOGY (2014) [E3]
Author URL
Co-authorsLisa Wood, Vanessa Mcdonald, Peter Gibson, Michael Hensley
2013Scott HA, Gibson PG, Garg ML, Smart J, Wood LG, 'Female Reproductive Stage Drives The Association Between Obesity And Neutrophilic Airway Inflammation In Adults With Asthma', American Journal of Respiratory and Critical Care Medicine, Philadelphia, PA (2013) [E3]
Co-authorsManohar Garg, Peter Gibson, Lisa Wood
2013Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'The Association Between Obesity and Asthma is Driven By Female Reproductive Stage', Australasian Medical Journal, Brisbane (2013) [E3]
Co-authorsLisa Wood, Peter Gibson, Manohar Garg
2013Scott HA, Gibson PG, Garg ML, Smart J, Wood LG, 'REPRODUCTIVE STAGE DRIVES LINK BETWEEN OBESITY AND NEUTROPHILIC AIRWAY INFLAMMATION IN FEMALES WITH ASTHMA', RESPIROLOGY (2013) [E3]
Author URL
Co-authorsManohar Garg, Peter Gibson, Lisa Wood
2012Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Female reproductive stage drives the association between obesity and neutrophilic airway inflammation in adults with asthma', Abstracts. American Thoracic Society 2012 International Conference, San Francisco, CA (2012) [E3]
Co-authorsManohar Garg, Peter Gibson, Lisa Wood
2012Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Reproductive stage drives link between obesity and neutrophilic airway inflammation in females with asthma', Abstracts. TSANZ Annual Scientific Meeting 2012, Canberra, ACT (2012) [E3]
Co-authorsLisa Wood, Manohar Garg, Peter Gibson
2012Wood LG, Garg ML, Smart JM, Scott HA, Barker D, Gibson PG, 'Manipulating antioxidant intake in asthma: A randomized clinical trial', Respirology, Canberra, ACT (2012) [E3]
CitationsWeb of Science - 2
Co-authorsPeter Gibson, Manohar Garg, Lisa Wood
2012Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Weight loss improves clinical asthma outcomes and airway inflammation in overweight and obese asthmatics', Obesity Research & Clinical Practice, Auckland, New Zealand (2012) [E3]
Co-authorsRobin Callister, Manohar Garg, Peter Gibson, Lisa Wood, Philip Morgan
2011Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'The influence of body composition and inflammation on lung function in asthma', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
Co-authorsLisa Wood, Peter Gibson, Philip Morgan, Robin Callister, Manohar Garg
2011Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Clinical asthma outcomes are improved after body fat reduction in overweight and obese asthmatics', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
Co-authorsPhilip Morgan, Peter Gibson, Lisa Wood, Manohar Garg, Robin Callister
2011Wood LG, Scott HA, Gibson PG, 'Systemic inflammation is increased in neutrophilic asthma', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
Co-authorsLisa Wood, Peter Gibson
2011Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Success in a weight loss trial is greatest in subjects with more severe asthma', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
Co-authorsPeter Gibson, Philip Morgan, Robin Callister, Manohar Garg, Lisa Wood
2011Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Success in a weight loss trial is related to asthma severity', Respirology, Perth, WA (2011) [E3]
Co-authorsLisa Wood, Peter Gibson, Philip Morgan, Robin Callister, Manohar Garg
2011Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Body fat reduction improves clinical asthma outcomes in overweight and obese asthma', Respirology, Perth, WA (2011) [E3]
Co-authorsPhilip Morgan, Robin Callister, Manohar Garg, Peter Gibson, Lisa Wood
2011Wood LG, Scott HA, Gibson PG, 'The neutrophilic inflammatory phenotype is associated increased systemic inflammation in asthma', Respirology, Perth, WA (2011) [E3]
Co-authorsLisa Wood, Peter Gibson
2011Fu J, Baines KJ, Wood LG, Scott HA, Gibson PG, 'Low-grade systemic inflammation is associated with airway neutrophilia in asthma', Respirology, Shanghai (2011) [E3]
Co-authorsKatherine Baines, Peter Gibson, Lisa Wood
2011Fu J, Baines KJ, Gibson PG, Scott HA, Wood LG, 'Systemic inflammation mediates airway neutrophilia via the regulation of IL-8 receptor mRNA expression', Respirology, Shanghai (2011) [E3]
Co-authorsLisa Wood, Peter Gibson, Katherine Baines
2010Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Fatty acids and obesity differentially affect airway inflammation in males and females with asthma', American Journal of Respiratory and Critical Care Medicine, New Orleans (2010) [E3]
Co-authorsManohar Garg, Lisa Wood, Peter Gibson
2010Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Caloric restriction and exercise improve clinical asthma outcomes in overweight and obese asthma', Obesity Research & Clinical Practice, Sydney, NSW (2010) [E3]
Co-authorsPhilip Morgan, Manohar Garg, Robin Callister, Lisa Wood, Peter Gibson
2010Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Caloric consumption and exercise improve clinical asthma outcomes in overweight and obese asthma', Obesity Research and Clinical Practice, Sydney, NSW (2010) [E3]
Co-authorsPhilip Morgan, Manohar Garg, Peter Gibson, Lisa Wood, Robin Callister
2010Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Clinical asthma outcomes are improved by caloric restriction and exercise in overweight and obese asthma', Proceedings of the Nutrition Society of Australia, Perth (2010) [E3]
Co-authorsRobin Callister, Manohar Garg, Peter Gibson, Lisa Wood, Philip Morgan
2009Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Plasma fatty acid profiles are different in obese versus non-obese asthma', Proceedings of the Nutrition Society of Australia, Newcastle, NSW (2009) [E3]
Co-authorsManohar Garg, Peter Gibson, Lisa Wood
2009Scott HA, Gibson PG, Garg ML, Smart J, Wood LG, 'Neutrophilic Airway Inflammation Links Asthma and Obesity', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2009) [E3]
Author URL
Co-authorsManohar Garg, Peter Gibson, Lisa Wood
2009Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Asthma and obesity are linked via neutrophilic airway inflammation', Respirology, Darwin, NT (2009) [E3]
DOI10.1111/j.1440-1843.2009.01503_1.x
Co-authorsLisa Wood, Peter Gibson, Manohar Garg
2008Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Obesity is associated with increased inflammation in asthma', Asia Pacific Journal of Clinical Nutrition, Adelaide, SA (2008) [E3]
Co-authorsLisa Wood, Manohar Garg, Peter Gibson
Show 23 more conferences
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Grants and Funding

Summary

Number of grants7
Total funding$267,367

Click on a grant title below to expand the full details for that specific grant.


20144 grants / $218,648

Understanding the Beneficial Role of Exercise in Modifying Eosinophilic Airway Inflammation in Asthma$160,000

This project will examine the concept that exercise assists in optimising asthma management. While it is well established that exercise has multiple benefits on general health, relatively little attention has been paid to the potential therapeutic effects of exercise in modifying inflammation in asthma. We have recently published a study showing that moderate-intensity aerobic exercise can reduce airway eosinophilia in adults with asthma. This project will build on this exciting data, by examining the importance of exercise intensity and assessing the mechanisms through which exercise exerts these beneficial effects.
Funding body: Thoracic Society of Australia and New Zealand

Funding bodyThoracic Society of Australia and New Zealand
Project Team
SchemePostdoctoral Respiratory Research Fellowship
RoleLead
Funding Start2014
Funding Finish2016
GNo
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Greaves Family Early Career Support Grant$30,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamDoctor Hayley Scott
SchemeBridging Grant
RoleLead
Funding Start2014
Funding Finish2014
GNoG1301292
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Exercise Training as a Potential Treatment for Eosinophilic Airway Inflammation in Asthma$26,648

Funding body: John Hunter Hospital Charitable Trust Fund

Funding bodyJohn Hunter Hospital Charitable Trust Fund
Project TeamDoctor Hayley Scott, Associate Professor Lisa Wood, Conjoint Associate Professor Nick Saltos
SchemeResearch Grant
RoleLead
Funding Start2014
Funding Finish2014
GNoG1400219
Type Of FundingOther Public Sector - State
Category2OPS
UONY

12th International congress on Obesity, Kuala Lumpur Malaysia, 17-20 March 2014$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding bodyUniversity of Newcastle - Faculty of Health and Medicine
Project TeamDoctor Hayley Scott
SchemeTravel Grant
RoleLead
Funding Start2014
Funding Finish2014
GNoG1400427
Type Of FundingInternal
CategoryINTE
UONY

20131 grants / $23,810

The Effect of Exercise on Asthmatic Airway Inflammation$23,810

Funding body: John Hunter Hospital Charitable Trust Fund

Funding bodyJohn Hunter Hospital Charitable Trust Fund
Project TeamDoctor Hayley Scott, Conjoint Associate Professor Nick Saltos
SchemeResearch Grant
RoleLead
Funding Start2013
Funding Finish2013
GNoG1300780
Type Of FundingOther Public Sector - State
Category2OPS
UONY

20122 grants / $24,909

Follow-Up of a Weight Loss Intervention in COPD$14,989

Funding body: John Hunter Hospital Charitable Trust Fund

Funding bodyJohn Hunter Hospital Charitable Trust Fund
Project TeamAssociate Professor Lisa Wood, Doctor Hayley Scott, Emeritus Professor Michael Hensley
SchemeResearch Grant
RoleInvestigator
Funding Start2012
Funding Finish2012
GNoG1200763
Type Of FundingOther Public Sector - State
Category2OPS
UONY

The Role of Sex Hormones and Leptin in Obese-Asthma$9,920

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamDoctor Hayley Scott
SchemeEarly Career Researcher Grant
RoleLead
Funding Start2012
Funding Finish2012
GNoG1200809
Type Of FundingInternal
CategoryINTE
UONY
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Research Supervision

Past Supervision

YearResearch Title / Program / Supervisor Type
2014Evaluation of a weight loss intervention in obese COPD subjects
Nutrition & Dietetics, University of Newcastle
Co-Supervisor
2014Effect of Exercise on Asthmatic Airway Inflammation
Medical Science, University of Newcastle
Co-Supervisor
2013Adipokines and the role in overweight and obese asthma
Nutrition & Dietetics, University of Newcastle
Co-Supervisor
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Dr Hayley Scott

Position

Conjoint Fellow
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine

Contact Details

Emailhayley.scott@newcastle.edu.au
Phone07 3443 7126
Fax07 3443 7779

Office

RoomLevel 5 West
BuildingTranslational Research Institute
LocationLung and Allergy Research Centre. 37 Kent Street, Woolloongabba QLD 4102

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