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Dr Hayley Scott

Conjoint Fellow

School of Biomedical Sciences and Pharmacy

Career Summary

Biography

Dr Scott is a Conjoint Postdoctoral Research Fellow for the Priority Research Centre in Asthma and Respiratory Diseases, while she completes her postdoctoral studies at the Lung and Allergy Research Centre at the University of Queensland. Her research investigates the roles of obesity, exercise and nutrition in promoting or impeding inflammation and, ultimately, the effect this has on the pathogenesis of respiratory diseases including asthma and COPD.

She was the first internationally to demonstrate an inflammatory mechanism driving the association between obesity and asthma, and has also investigated whether weight loss (by dietary restriction and/or increasing exercise) is a potential treatment strategy for obese asthmatics. This study found that loss of fat tissue within the gynoid region is associated with a reduction to airway inflammation in females, while in males a reduced dietary intake of saturated fat was associated with a reduction to airway inflammation. This suggests that these changes are operating via different mechanisms in males versus females and, importantly, the obese-asthma association is responsive to dietary manipulation. Hayley has also investigated the potential therapeutic effects of exercise in asthma and found that a 10-week exercise training program resulted in a significant 5-fold reduction to airway inflammation and improved asthma-related quality of life. Her research was the first to establish that a 5-10% weight loss is associated with clinically important improvements to asthma control in 58% of patients and asthma-related quality of life in 83% of patients. Prior to this there was no specific weight loss target for obese asthmatics, and since its publication has been translated into practice as the target weight loss goal published in the “Asthma and Healthy Living” brochures by the National Asthma Council Australia, which is distributed to both general practitioners and patients nationally. More recently, Dr Scott has expanded her research into elucidating the role of exercise in reducing asthmatic airway inflammation and found that a one-off exercise session reduces inflammation in the airways, which has led her to commence an RCT as part of her postdoctoral studies aimed at elucidating whether exercise intensity impacts the response to exercise in those with asthma.

Dr Scott's qualification as a dietitian positions her uniquely within the field, as she is able to perform specialised dietary manipulations to achieve a desired clinical outcome. For example, she recently performed weight loss counselling in 30 adults with COPD, achieving an average weight loss of 10% in 3 months, maintenance of lean muscle mass and corresponding clinically important improvement in several disease outcomes linked with morbidity and mortality. She has also performed weight loss counselling in patients with asthma resulting in an average weight loss of 8% in 10 weeks, with significant improvements to asthma symptoms and asthma-related quality of life, as well as completed dietary manipulation of antioxidants, which modified patients risk of experiencing an asthma exacerbation. She has expertise in many specialised clinical techniques including venepuncture, hypertonic saline challenge and sputum collection, body composition and bone density analysis using dual-energy x-ray absorptiometry (DXA) and lung function testing, while her research utilises advanced laboratory techniques including measuring gene expression, and HPLC and GC for quantifying nutritional markers such as antioxidants and fatty acids. 

Research Expertise
Dr Scott is a Conjoint Postdoctoral Research Fellow for the Priority Research Centre in Asthma and Respiratory Diseases, while she is undertaking postdoctoral research at the Lung and Allergy Research Centre at the University of Queensland. Hayley completed her PhD in 2012, which sought to examine the mechanisms driving the association between obesity and asthma. This research was the first internationally to propose a plausible inflammatory mechanism driving the association between obesity and asthma. She then utilised her skills as a dietitian to design and undertake a randomised trial, where she examined the effects of weight loss in those with asthma to examine whether the detrimental effects of obesity in asthma could be reversed. This study was the first internationally to propose that a 5-10% weight loss was associated with clinically important improvements to asthma in most patients, and since its publication has been incorporated as a weight loss goal in the “Asthma and Healthy Living” brochures by the National Asthma Council Australia, which has been distributed to both general practitioners and patients nationally. Dr Scott's research has identified three common drivers of the obese-asthma phenotype, which her research focuses on: 1. Excess fat tissue: Dr Scott's research has shown that adiposity is associated with neutrophilic airway inflammation in those with asthma. When examined by sex, this relationship is only apparent in females, while weight loss reduces this inflammation in females. Neutrophilic airway inflammation is associated with the most severe forms of asthma and is not responsive to inhaled corticosteroid medications, the mainstay of asthma pharmacotherapy. Dr Scott is undertaking research to examine the hormonal drivers of this sex-specific effect with the hope of identifying alternate treatment options. 2. Exercise: Obesity is often associated with a low level of exercise. Dr Scott's research has shown that 10 weeks of exercise results in a five-fold reduction in eosinophilic airway inflammation, suggesting exercise is an important adjuvant asthma therapy and may be particularly useful for those who are refractory to current asthma therapies. Hayley is now conducting a randomised controlled trial aimed at elucidating how exercise intensity may have different inflammatory effects in those with asthma. 3. Dietary fat: Obesity is also often associated with a high dietary fat intake, with Dr Scott's research indicating that a high dietary fat intake is associated with increased neutrophilic airway inflammation in males with asthma, while restricting dietary fat intake is associated with a reduction in neutrophilic airway inflammation in males, suggesting reversibility of this phenomenon. The excellence of Dr Scott’s work has been recognised externally as she was awarded the Emerging Researcher for 2011 by the Nestle Nutrition Institute and Nutrition Society of Australia (NSA). More recently she was awarded the NSA Early Career Travel Grant, and has been awarded five conference travel awards since 2008. She was Chair of the Nutrition Society of Australia (Newcastle Branch) in 2012-2014, but in 2015 she stepped down to expand her postdoctoral research in Brisbane. Her research goal is to utilise her expertise in nutrition, weight loss counselling, exercise, body composition analysis and respiratory disease to ensure we gain a better understanding of the independent roles of obesity, exercise and dietary factors in driving respiratory disease outcomes, to enable optimisation of the clinical management of this population.


Qualifications

  • PhD, University of Newcastle
  • Bachelor of Nutrition and Dietetics (Honours), University of Newcastle

Keywords

  • Asthma
  • Fatty acids
  • Inflammation
  • Nutrition
  • Obesity
  • Respiratory Disease

Fields of Research

Code Description Percentage
110199 Medical Biochemistry and Metabolomics not elsewhere classified 50
110203 Respiratory Diseases 50

Professional Experience

UON Appointment

Title Organisation / Department
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (1 outputs)

Year Citation Altmetrics Link
2013 Scott H, Wood LG, Garg ML, Gibson PG, 'Asthma and Inflammation', Nutrition and Physical activity in inflammatory diseases, CABI, Oxford, UK 299-321 (2013) [B1]
Co-authors Manohar Garg, Lisa Wood, Peter Gibson

Journal article (14 outputs)

Year Citation Altmetrics Link
2015 Periyalil HA, Wood LG, Scott HA, Jensen ME, Gibson PG, 'Macrophage activation, age and sex effects of immunometabolism in obese asthma', EUROPEAN RESPIRATORY JOURNAL, 45 388-395 (2015)
DOI 10.1183/09031936.00080514
Citations Scopus - 1Web of Science - 1
Co-authors Peter Gibson, Lisa Wood
2015 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Determinants of weight loss success utilizing a meal replacement plan and/or exercise, in overweight and obese adults with asthma.', Respirology, 20 243-250 (2015)
DOI 10.1111/resp.12423
Citations Scopus - 1Web of Science - 1
Co-authors Manohar Garg, Peter Gibson, Robin Callister, Philip Morgan, Lisa Wood
2015 Scott HA, Latham JR, Callister R, Pretto JJ, Baines K, Saltos N, et al., 'Acute exercise is associated with reduced exhaled nitric oxide in physically inactive adults with asthma', Annals of Allergy, Asthma and Immunology, 114 470-479 (2015)

Background Although exercise has multiple health benefits, relatively little attention has been paid to its potential therapeutic effects in those with asthma. Objective To examin... [more]

Background Although exercise has multiple health benefits, relatively little attention has been paid to its potential therapeutic effects in those with asthma. Objective To examine the effects of acute exercise on inflammation in physically inactive and active adults with asthma. Methods Fourteen adults with asthma (n = 6 physically inactive, n = 8 physically active) completed (1) 30 minutes of moderate-intensity exercise on a treadmill and (2) 30 minutes of rest in random order, with 4 weeks between sessions. Exhaled nitric oxide (eNO) was measured before and after the intervention (0, 0.5, 1, 2, 4, and 24 hours). Blood inflammatory mediators were measured before and after the intervention (0, 2, and 24 hours). Results Physically inactive participants had a significant decrease in eNO 4 hours after exercise (-4.8 ppb, -6.4 to -0.5 ppb, P =.028), which was not observed in physically active participants (P =.362). Interluekin-1 receptor antagonist increased in the physically inactive group 2 hours after exercise, with this increase strongly correlated with the decrease in eNO at 4 hours (R = -0.685, P =.007) and 24 hours (R = -0.659, P =.014) after exercise. Interleukin-6 was increased significantly 2 hours after exercise in physically inactive participants. Blood neutrophils and nuclear factor erythroid 2-like 2 gene expression were increased 2 hours after exercise in the overall cohort. Conclusion This study demonstrates that acute moderate-intensity exercise is associated with decreased eNO in physically inactive adults with asthma and suggests that interluekin-1 receptor antagonist could have a role in mediating this effect. The attenuated response in physically active participants might be due to the sustained anti-inflammatory effects of exercise training. Future studies should investigate the impact of exercise intensity and exercise training on airway inflammation in those with asthma.

DOI 10.1016/j.anai.2015.04.002
Co-authors Lisa Wood, Robin Callister
2015 Scott HA, Latham JR, Callister R, Pretto JJ, Baines K, Saltos N, et al., 'Acute exercise is associated with reduced exhaled nitric oxide in physically inactive adults with asthma', Annals of Allergy, Asthma and Immunology, (2015)

Background: Although exercise has multiple health benefits, relatively little attention has been paid to its potential therapeutic effects in those with asthma. Objective: To exam... [more]

Background: Although exercise has multiple health benefits, relatively little attention has been paid to its potential therapeutic effects in those with asthma. Objective: To examine the effects of acute exercise on inflammation in physically inactive and active adults with asthma. Methods: Fourteen adults with asthma (n= 6 physically inactive, n= 8 physically active) completed (1) 30 minutes of moderate-intensity exercise on a treadmill and (2) 30 minutes of rest in random order, with 4 weeks between sessions. Exhaled nitric oxide (eNO) was measured before and after the intervention (0, 0.5, 1, 2, 4, and 24 hours). Blood inflammatory mediators were measured before and after the intervention (0, 2, and 24 hours). Results: Physically inactive participants had a significant decrease in eNO 4 hours after exercise (-4.8 ppb,-6.4 to-0.5 ppb, P= .028), which was not observed in physically active participants (P= .362). Interluekin-1 receptor antagonist increased in the physically inactive group 2 hours after exercise, with this increase strongly correlated with the decrease in eNO at 4 hours (R=-0.685, P= .007) and 24 hours (R=-0.659, P=.014) after exercise. Interleukin-6 was increased significantly 2 hours after exercise in physically inactive participants. Blood neutrophils and nuclear factor erythroid 2-like 2 gene expression were increased 2hours after exercise in the overall cohort. Conclusion: This study demonstrates that acute moderate-intensity exercise is associated with decreased eNO in physically inactive adults with asthma and suggests that interluekin-1 receptor antagonist could have a role in mediating this effect. The attenuated response in physically active participants might be due to the sustained anti-inflammatory effects of exercise training. Future studies should investigate the impact of exercise intensity and exercise training on airway inflammation in those with asthma. Trial registration: Australian New Zealand Clinical Trials Registry (http://www.anzctr.org.au), registration number ACTRN12613001014741.

DOI 10.1016/j.anai.2015.04.002
Co-authors Lisa Wood, Katherine Baines, Robin Callister
2014 Scott HA, Jensen ME, Wood LG, 'Dietary interventions in asthma', Current Pharmaceutical Design, 20 1003-1010 (2014) [C1]

Asthma is a chronic inflammatory disorder of the airways. The inflammatory response in asthma is heterogeneous. Allergen specific responses lead to activation of the acquired immu... [more]

Asthma is a chronic inflammatory disorder of the airways. The inflammatory response in asthma is heterogeneous. Allergen specific responses lead to activation of the acquired immune system, via a predominantly IL-5 mediated, eosinophilic pathway. Stimuli such as viruses and bacteria activate the innate immune system, via a predominantly IL-8 mediated, neutrophilic pathway. Asthma has also been demonstrated to involve a systemic inflammatory component. Glucocorticoids are the predominant pharmacological treatment used to control inflammation in asthma. However, compliance with medications can be compromised due to patient concerns about side effects. Hence dietary interventions that target the inflammatory response in asthma have great potential. Various aspects of dietary intake are known to modulate inflammation. Saturated fatty acids can induce an inflammatory response via activation of pattern recognition receptors. Omega-3 fatty acids can be anti-inflammatory, via mechanisms such as modification of eicosanoid production. Antioxidants can have anti-inflammatory effects as they scavenge free radicals, preventing activation of transcription factors including NF-¿B. Chronic excess energy intake can lead to obesity, which augments inflammation due to the release of inflammatory mediators by adipose tissue. Here we review the role of these dietary components in asthma. © 2014 Bentham Science Publishers.

DOI 10.2174/13816128113190990421
Citations Scopus - 4Web of Science - 5
Co-authors Lisa Wood
2014 Morgan PJ, Scott HA, Young MD, Plotnikoff RC, Collins CE, Callister R, 'Associations between program outcomes and adherence to Social Cognitive Theory tasks: process evaluation of the SHED-IT community weight loss trial for men', INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY, 11 (2014) [C1]
DOI 10.1186/s12966-014-0089-9
Citations Web of Science - 3
Co-authors Robin Callister, Myles Young, Clare Collins, Ron Plotnikoff, Philip Morgan
2013 Morgan PJ, Barnett LM, Cliff DP, Okely AD, Scott HA, Cohen KE, Lubans DR, 'Fundamental movement skill interventions in youth: A systematic review and meta-analysis', Pediatrics, 132 (2013) [C1]
DOI 10.1542/peds.2013-1167
Citations Scopus - 10Web of Science - 9
Co-authors David Lubans, Philip Morgan
2013 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Dietary restriction and exercise improve airway inflammation and clinical outcomes in overweight and obese asthma: a randomized trial', Clinical and Experimental Allergy, 43 36-49 (2013) [C1]
DOI 10.1111/cea.12004
Citations Scopus - 25Web of Science - 23
Co-authors Lisa Wood, Peter Gibson, Manohar Garg, Robin Callister, Philip Morgan
2012 Wood LG, Garg ML, Smart JM, Scott HA, Barker D, Gibson PG, 'Manipulating antioxidant intake in asthma: A randomized controlled trial', American Journal of Clinical Nutrition, 96 534-543 (2012) [C1]
Citations Scopus - 27Web of Science - 26
Co-authors Lisa Wood, Peter Gibson, Manohar Garg
2012 Wood LG, Baines KJ, Fu J, Scott HA, Gibson PG, 'The neutrophilic inflammatory phenotype is associated with systemic inflammation in asthma', Chest, 142 86-93 (2012) [C1]
Citations Scopus - 47Web of Science - 44
Co-authors Peter Gibson, Lisa Wood, Katherine Baines
2012 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Relationship between body composition, inflammation and lung function in overweight and obese asthma', Respiratory Research, 13 1-10 (2012) [C1]
Citations Scopus - 10Web of Science - 8
Co-authors Philip Morgan, Robin Callister, Manohar Garg, Lisa Wood, Peter Gibson
2011 Scott HA, Gibson PG, Garg ML, Wood LG, 'Airway inflammation is augmented by obesity and fatty acids in asthma', European Respiratory Journal, 38 594-602 (2011) [C1]
Citations Scopus - 68Web of Science - 62
Co-authors Manohar Garg, Lisa Wood, Peter Gibson
2009 Wood LG, Scott HA, Garg ML, Gibson PG, 'Innate immune mechanisms linking non-esterified fatty acids and respiratory disease', Progress in Lipid Research, 48 27-43 (2009) [C1]
DOI 10.1016/j.plipres.2008.10.001
Citations Scopus - 23Web of Science - 18
Co-authors Manohar Garg, Lisa Wood, Peter Gibson
2009 McFarlane J, Scott HA, Robertson VJ, Gleeson C, Vanderkroft D, Wilson K, 'General practitioner and paediatrician self-reported capacity for the diagnosis and management of childhood and adolescent overweight and obesity', Nutrition & Dietetics, 66 176-185 (2009) [C1]
DOI 10.1111/j.1747-0080.2009.01363.x
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Conference (26 outputs)

Year Citation Altmetrics Link
2014 Periyalil H, Scott H, Jensen M, Wood L, Gibson P, 'MACROPHAGE ACTIVATION IS A DETERMINANT OF DEVELOPMENTAL EFFECTS OF IMMUNOMETABOLISM IN OBESE ASTHMA', RESPIROLOGY (2014) [E3]
DOI 10.1111/resp.12263_7
Co-authors Lisa Wood, Peter Gibson
2014 Mcdonald V, Gibson P, Scott H, Baines P, Hensley M, Pretto J, Wood L, 'SHOULD WE TREAT OBESITY IN COPD? THE EFFECTS OF WEIGHT LOSS AND RESISTANCE TRAINING IN OBESE COPD', RESPIROLOGY (2014) [E3]
Co-authors Michael Hensley, Vanessa Mcdonald, Peter Gibson, Lisa Wood
2013 Scott HA, Gibson PG, Garg ML, Smart J, Wood LG, 'Female Reproductive Stage Drives The Association Between Obesity And Neutrophilic Airway Inflammation In Adults With Asthma', American Journal of Respiratory and Critical Care Medicine, Philadelphia, PA (2013) [E3]
Co-authors Manohar Garg, Peter Gibson, Lisa Wood
2013 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'The Association Between Obesity and Asthma is Driven By Female Reproductive Stage', Australasian Medical Journal, Brisbane (2013) [E3]
Co-authors Lisa Wood, Peter Gibson, Manohar Garg
2013 Scott HA, Gibson PG, Garg ML, Smart J, Wood LG, 'REPRODUCTIVE STAGE DRIVES LINK BETWEEN OBESITY AND NEUTROPHILIC AIRWAY INFLAMMATION IN FEMALES WITH ASTHMA', RESPIROLOGY (2013) [E3]
Co-authors Manohar Garg, Peter Gibson, Lisa Wood
2012 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Female reproductive stage drives the association between obesity and neutrophilic airway inflammation in adults with asthma', Abstracts. American Thoracic Society 2012 International Conference, San Francisco, CA (2012) [E3]
Co-authors Manohar Garg, Peter Gibson, Lisa Wood
2012 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Reproductive stage drives link between obesity and neutrophilic airway inflammation in females with asthma', Abstracts. TSANZ Annual Scientific Meeting 2012, Canberra, ACT (2012) [E3]
Co-authors Lisa Wood, Manohar Garg, Peter Gibson
2012 Wood LG, Garg ML, Smart JM, Scott HA, Barker D, Gibson PG, 'Manipulating antioxidant intake in asthma: A randomized clinical trial', Respirology, Canberra, ACT (2012) [E3]
Citations Web of Science - 2
Co-authors Peter Gibson, Manohar Garg, Lisa Wood
2012 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Weight loss improves clinical asthma outcomes and airway inflammation in overweight and obese asthmatics', Obesity Research & Clinical Practice, Auckland, New Zealand (2012) [E3]
Co-authors Robin Callister, Manohar Garg, Peter Gibson, Lisa Wood, Philip Morgan
2011 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'The influence of body composition and inflammation on lung function in asthma', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
Co-authors Lisa Wood, Peter Gibson, Philip Morgan, Robin Callister, Manohar Garg
2011 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Clinical asthma outcomes are improved after body fat reduction in overweight and obese asthmatics', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
Co-authors Philip Morgan, Peter Gibson, Lisa Wood, Manohar Garg, Robin Callister
2011 Wood LG, Scott HA, Gibson PG, 'Systemic inflammation is increased in neutrophilic asthma', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
Co-authors Lisa Wood, Peter Gibson
2011 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Success in a weight loss trial is greatest in subjects with more severe asthma', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
Co-authors Peter Gibson, Philip Morgan, Robin Callister, Manohar Garg, Lisa Wood
2011 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Success in a weight loss trial is related to asthma severity', Respirology, Perth, WA (2011) [E3]
Co-authors Lisa Wood, Peter Gibson, Philip Morgan, Robin Callister, Manohar Garg
2011 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Body fat reduction improves clinical asthma outcomes in overweight and obese asthma', Respirology, Perth, WA (2011) [E3]
Co-authors Philip Morgan, Robin Callister, Manohar Garg, Peter Gibson, Lisa Wood
2011 Wood LG, Scott HA, Gibson PG, 'The neutrophilic inflammatory phenotype is associated increased systemic inflammation in asthma', Respirology, Perth, WA (2011) [E3]
Co-authors Lisa Wood, Peter Gibson
2011 Fu J, Baines KJ, Wood LG, Scott HA, Gibson PG, 'Low-grade systemic inflammation is associated with airway neutrophilia in asthma', Respirology, Shanghai (2011) [E3]
Co-authors Katherine Baines, Peter Gibson, Lisa Wood
2011 Fu J, Baines KJ, Gibson PG, Scott HA, Wood LG, 'Systemic inflammation mediates airway neutrophilia via the regulation of IL-8 receptor mRNA expression', Respirology, Shanghai (2011) [E3]
Co-authors Lisa Wood, Peter Gibson, Katherine Baines
2010 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Fatty acids and obesity differentially affect airway inflammation in males and females with asthma', American Journal of Respiratory and Critical Care Medicine, New Orleans (2010) [E3]
Co-authors Manohar Garg, Lisa Wood, Peter Gibson
2010 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Caloric restriction and exercise improve clinical asthma outcomes in overweight and obese asthma', Obesity Research & Clinical Practice, Sydney, NSW (2010) [E3]
Co-authors Philip Morgan, Manohar Garg, Robin Callister, Lisa Wood, Peter Gibson
2010 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Caloric consumption and exercise improve clinical asthma outcomes in overweight and obese asthma', Obesity Research and Clinical Practice, Sydney, NSW (2010) [E3]
Co-authors Philip Morgan, Manohar Garg, Peter Gibson, Lisa Wood, Robin Callister
2010 Scott HA, Gibson PG, Garg ML, Pretto JJ, Morgan PJ, Callister R, Wood LG, 'Clinical asthma outcomes are improved by caloric restriction and exercise in overweight and obese asthma', Proceedings of the Nutrition Society of Australia, Perth (2010) [E3]
Co-authors Robin Callister, Manohar Garg, Peter Gibson, Lisa Wood, Philip Morgan
2009 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Plasma fatty acid profiles are different in obese versus non-obese asthma', Proceedings of the Nutrition Society of Australia, Newcastle, NSW (2009) [E3]
Co-authors Manohar Garg, Peter Gibson, Lisa Wood
2009 Scott HA, Gibson PG, Garg ML, Smart J, Wood LG, 'Neutrophilic Airway Inflammation Links Asthma and Obesity', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2009) [E3]
Co-authors Manohar Garg, Peter Gibson, Lisa Wood
2009 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Asthma and obesity are linked via neutrophilic airway inflammation', Respirology, Darwin, NT (2009) [E3]
DOI 10.1111/j.1440-1843.2009.01503_1.x
Co-authors Lisa Wood, Peter Gibson, Manohar Garg
2008 Scott HA, Gibson PG, Garg ML, Smart JM, Wood LG, 'Obesity is associated with increased inflammation in asthma', Asia Pacific Journal of Clinical Nutrition, Adelaide, SA (2008) [E3]
Co-authors Lisa Wood, Manohar Garg, Peter Gibson
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Grants and Funding

Summary

Number of grants 7
Total funding $267,367

Click on a grant title below to expand the full details for that specific grant.


20144 grants / $218,648

Understanding the Beneficial Role of Exercise in Modifying Eosinophilic Airway Inflammation in Asthma$160,000

This project will examine the concept that exercise assists in optimising asthma management. While it is well established that exercise has multiple benefits on general health, relatively little attention has been paid to the potential therapeutic effects of exercise in modifying inflammation in asthma. We have recently published a study showing that moderate-intensity aerobic exercise can reduce airway eosinophilia in adults with asthma. This project will build on this exciting data, by examining the importance of exercise intensity and assessing the mechanisms through which exercise exerts these beneficial effects.

Funding body: Thoracic Society of Australia and New Zealand

Funding body Thoracic Society of Australia and New Zealand
Project Team
Scheme Postdoctoral Respiratory Research Fellowship
Role Lead
Funding Start 2014
Funding Finish 2016
GNo
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Greaves Family Early Career Support Grant$30,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Hayley Scott
Scheme Bridging Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1301292
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Exercise Training as a Potential Treatment for Eosinophilic Airway Inflammation in Asthma$26,648

Funding body: John Hunter Hospital Charitable Trust Fund

Funding body John Hunter Hospital Charitable Trust Fund
Project Team Doctor Hayley Scott, Associate Professor Lisa Wood, Conjoint Associate Professor Nick Saltos
Scheme Research Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1400219
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

12th International congress on Obesity, Kuala Lumpur Malaysia, 17-20 March 2014$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Doctor Hayley Scott
Scheme Travel Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1400427
Type Of Funding Internal
Category INTE
UON Y

20131 grants / $23,810

The Effect of Exercise on Asthmatic Airway Inflammation$23,810

Funding body: John Hunter Hospital Charitable Trust Fund

Funding body John Hunter Hospital Charitable Trust Fund
Project Team Doctor Hayley Scott, Conjoint Associate Professor Nick Saltos
Scheme Research Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1300780
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

20122 grants / $24,909

Follow-Up of a Weight Loss Intervention in COPD$14,989

Funding body: John Hunter Hospital Charitable Trust Fund

Funding body John Hunter Hospital Charitable Trust Fund
Project Team Associate Professor Lisa Wood, Doctor Hayley Scott, Emeritus Professor Michael Hensley
Scheme Research Grant
Role Investigator
Funding Start 2012
Funding Finish 2012
GNo G1200763
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

The Role of Sex Hormones and Leptin in Obese-Asthma$9,920

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Hayley Scott
Scheme Early Career Researcher Grant
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1200809
Type Of Funding Internal
Category INTE
UON Y
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Research Supervision

Past Supervision

Year Research Title / Program / Supervisor Type
2014 Evaluation of a weight loss intervention in obese COPD subjects
Nutrition & Dietetics, University of Newcastle
Co-Supervisor
2014 Effect of Exercise on Asthmatic Airway Inflammation
Medical Science, University of Newcastle
Co-Supervisor
2013 Adipokines and the role in overweight and obese asthma
Nutrition & Dietetics, University of Newcastle
Co-Supervisor
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Dr Hayley Scott

Position

Conjoint Fellow
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine

Contact Details

Email hayley.scott@newcastle.edu.au
Phone 07 3443 7126
Fax 07 3443 7779

Office

Room Level 5 West
Building Translational Research Institute
Location Lung and Allergy Research Centre. 37 Kent Street, Woolloongabba QLD 4102

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