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Career Summary

Biography

Dr Vanessa Murphy is a postdoctoral research scientist investigating the characteristics, mechanisms and consequences of asthma exacerbations during pregnancy and their health impact on both the mother and the baby. She began in this field full-time in 1999, with her PhD studies on the effects of maternal asthma on placental function and fetal development winning numerous awards, nationally and internationally. In 2004, with a competitive 3 year fellowship from the Hunter Medical Research Institute, she commenced her post-doctoral studies with the Centre for Asthma and Respiratory Diseases, under the supervision of Prof Peter Gibson, where she is continuing to build on her expertise in the area of asthma exacerbations and airway inflammation during pregnancy. Since 2006, Dr Murphy has pursued her research career part-time, and has taken three significant breaks from her career while having children. In 2007 she received her first project grant from the NHMRC, which investigated the mechanisms, characteristics and consequences of viral infections on asthma exacerbations during pregnancy, and she is currently funded by a part-time NHMRC fellowship which was also awarded in 2007. She is involved as an associate investigator on the NHMRC funded “Managing asthma in pregnancy” (MAP) randomised controlled trial, which successfully reduced the rate of severe exacerbations in pregnancy by managing treatment changes with the use of an objective marker of airway inflammation. This resulted in a high impact publication in Lancet in 2011. With pilot funding from HMRI, this study has now been extended to a birth cohort follow-up study, investigating the links between maternal asthma in pregnancy and the development of asthma in childhood, in collaboration with Paediatrician A/Prof Joerg Mattes and Prof Peter Gibson. A further highlight of recent years has been working on an exciting collaboration with the world leader in the field of asthma during pregnancy, Prof Michael Schatz and colleagues in San Diego, USA. Together, we have completed the first systematic review and meta-analysis examining the risks of adverse perinatal outcomes in women with asthma, which has resulted in a publication in the British Journal of Obstetrics and Gynaecology in 2011. Dr Murphy has been invited to write reviews several times, and this year was invited to speak at the European Respiratory Society Conference in Amsterdam in September on the management of asthma during pregnancy, demonstrating her recognition internationally in the field of asthma during pregnancy.

Qualifications

  • PhD, University of Newcastle, 03/09/2004
  • Bachelor of Medicinal Chemistry (Honours), University of Wollongong, 12/05/1999

Research

Research keywords

  • asthma
  • pregnancy

Research expertise

Vanessa's research expertise is in the area of asthma during pregnancy, covering the effects of asthma on pregnancy outcomes, the management of asthma during pregnancy, and the mechanisms of viral infection in pregnancy.

Languages

  • English

Fields of Research

CodeDescriptionPercentage
110299Cardiovascular Medicine And Haematology Not Elsewhere Classified35
111400Paediatrics And Reproductive Medicine35
160599Policy And Administration Not Elsewhere Classified30

Appointments

Australian Part-time Research Fellowship
National Health & Medical Research Council (Australia)
01/12/2007

Awards

Research Award.

2005Ian Potter Foundation Travel Grant
Ian Potter Foundation (Australia)
2005Young Scientist Sponsorship
European Respiratory Society (Denmark)
2004New Investigator Award
Perinatal Society of Australia and New Zealand (Australia)
2003Elsevier Science New Investigator Award
International Federation of Placenta Associations (Germany)
2002Australian Society for Medical Research (ASMR) Research Award
ASMR (Australia)
This award allowed me to travel to San Diego to complete a 3 month collaborative project with Ferring Research Insitute using novel proteomic techniques.
2002Best Oral Presentation by a Student
Fetal and Neonatal Physiological Society (Czech Republic)
2001Medibank Private Student Researcher Award
Australian Society for Medical Research (Australia)
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Publications

No publications.

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Grants and Funding

Summary

Number of grants25
Total funding$1,327,601

For project grants received where the lead institution is other than the University of Newcastle, details are shown in italics.

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2013 (4 grants)

Impact of fractional exhaled nitric oxide-based management of pregnancies with asthma on perinatal and infant outcomes $23,810
Funding Body: John Hunter Hospital Charitable Trust Fund

Project Team
Doctor Vanessa Murphy, Emeritus Professor Michael Hensley
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$23,81020132013
GNo:G1300782

Inflammometry-based management of asthma in pregnancy for the prevention of preterm birth: the iMAP study$20,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Vanessa Murphy
SchemeRole
Near MissChief Investigator
Total AmountFunding StartFunding Finish
$20,00020132013
GNo:G1300695

Inflammometry-based management of asthma in pregnancy for the prevention of preterm birth: the iMAP study$20,000
Funding Body: University of Newcastle

Project Team
Doctor Vanessa Murphy, Conjoint Professor Peter Gibson, Emeritus Professor Michael Hensley, Conjoint Professor Warwick Giles, Conjoint Associate Professor Andrew Bisits, Dr Kirsten McCaffery, Professor Paul Colditz, Professor Michael Peek
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$20,00020132013
GNo:G1300477

Effect of better asthma management in pregnancy on antiviral responses, atopy and airways inflammation in early childhood$10,000
Funding Body: University of Newcastle

Project Team
Professor Joerg Mattes, Conjoint Professor Peter Gibson, Doctor Vanessa Murphy
SchemeRole
Near Miss GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020132013
GNo:G1300476

2012 (2 grants)

Body plethysmograph respiratory function system$33,076
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Gibson, Conjoint Associate Professor Peter Wark, Associate Professor Lisa Wood, Associate Professor Jodie Simpson, Doctor Katie Baines, Doctor Vanessa Murphy, Mr Jeffrey Pretto, Emeritus Professor Michael Hensley, Ms Jenny Mackney
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$33,07620122012
GNo:G1100973

The Growing into Asthma Study: Wheezing prevalence and markers of airways inflammation in preschoolers born to mothers in asthma exacerbations in pregnancy$25,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Joerg Mattes, Conjoint Professor Peter Gibson, Emeritus Professor Michael Hensley, Conjoint Associate Professor Bruce Whitehead, Doctor Vanessa Murphy
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$25,00020122012
GNo:G1200662

2011 (1 grants)

Lung Function (Spirometry) testing and sputum induction equipment - establishing 3 new clinical workstations. Medgraphics CPFS/d USB spirometer with breezesuite software (x3). Laptop computer (x3). Ul$10,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Doctor Katie Baines, Conjoint Associate Professor Peter Wark, Doctor Vanessa Murphy
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020112011
GNo:G1100038

2010 (1 grants)

Real time PCR machine (Mastercycler ep realplex2 from Epprndorf) $34,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Jodie Simpson, Conjoint Professor Peter Gibson, Conjoint Associate Professor Peter Wark, Associate Professor Lisa Wood, Doctor Vanessa Murphy, Doctor Robert Scott, Doctor Katie Baines
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$34,00020102010
GNo:G1000056

2009 (2 grants)

Growing into asthma: A birth cohort study to investigate the prenatal and development origins of asthma$24,800
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Vanessa Murphy, Professor Joerg Mattes, Conjoint Professor Peter Gibson
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$24,80020092009
GNo:G0189802

Growing into asthma: a birth cohort study to investigate the prenatal and development origins of asthma$13,500
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Vanessa Murphy, Professor Joerg Mattes, Conjoint Professor Peter Gibson
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$13,50020092009
GNo:G0190487

2008 (2 grants)

Becton Dickinson high throughout sampler for the FACSCanto II cytometry system$35,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Associate Professor Peter Wark, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Doctor Vanessa Murphy, Professor Phil Hansbro
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$35,00020082008
GNo:G0188547

PULSE Education Prize$4,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Vanessa Murphy
SchemeRole
PULSE Education PrizeChief Investigator
Total AmountFunding StartFunding Finish
$4,00020082008
GNo:G0188538

2007 (6 grants)

Viral infection and exacerbations of asthma during pregnancy: characteristics, mechanisms and consequences$447,750
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Vanessa Murphy
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$447,75020072009
GNo:G0186434

Viral infection and exacerbations of asthma during pregnancy: characteristics, mechanisms and consequences$137,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Vanessa Murphy
SchemeRole
Training (Postdoctoral) Fellowships - Australian Part-time Research FellowshipChief Investigator
Total AmountFunding StartFunding Finish
$137,00020072010
GNo:G0186778

Nitric Oxide Monitoring System (NIOX)$45,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Peter Gibson, Conjoint Associate Professor Vicki Clifton, Conjoint Professor Warwick Giles, Emeritus Professor Michael Hensley, Doctor Vanessa Murphy, Conjoint Associate Professor Peter Wark, Doctor Vanessa McDonald, Associate Professor Jodie Simpson, Conjoint Associate Professor Bruce Whitehead, Professor Paul Foster, Professor Phil Hansbro, Associate Professor Lisa Wood
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$45,00020072007
GNo:G0188193

Class II biohazard containment hood and carbon dioxide cell culture incubator$20,000
Funding Body: NHMRC (National Health & Medical Research Council)

Hewlett Packard 7890 series gas chromatograph with accessories$20,000
Funding Body: NHMRC (National Health & Medical Research Council)

American Thoracic Society Conference, San Francisco, 18/5/2007 - 23/5/2007$2,500
Funding Body: University of Newcastle

Project Team
Doctor Vanessa Murphy
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,50020072007
GNo:G0187767

2006 (2 grants)

The relationship between eosinophilic inflammation, viral infection and severe asthma exacerbations during pregnancy$50,000
Funding Body: Asthma Foundation of New South Wales

Project Team
Doctor Vanessa Murphy, Conjoint Associate Professor Vicki Clifton, Emeritus Professor Michael Hensley, Conjoint Professor Warwick Giles, Conjoint Professor Peter Gibson
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$50,00020062006
GNo:G0186029

Viral infections and asthma exacerbations during pregnancy: characteristics, mechanisms and consequences$19,100
Funding Body: University of Newcastle

Project Team
Doctor Vanessa Murphy, Conjoint Associate Professor Vicki Clifton, Emeritus Professor Michael Hensley, Conjoint Professor Warwick Giles
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$19,10020062006
GNo:G0186061

2005 (2 grants)

American Thoracic Society Conference, 20 to 25 May 2005$2,000
Funding Body: Ian Potter Foundation

Project Team
Doctor Vanessa Murphy
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,00020052005
GNo:G0185081

American Thoracic Society Annual Scientific Conference, 20-25 May 2005$1,785
Funding Body: University of Newcastle

Project Team
Doctor Vanessa Murphy
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,78520052005
GNo:G0185399

2004 (1 grants)

Respiratory Medicine$269,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Vanessa Murphy, Conjoint Professor Peter Gibson
SchemeRole
Port Waratah Coal Service Post-Doctoral FellowshipChief Investigator
Total AmountFunding StartFunding Finish
$269,00020042006
GNo:G0184012

2003 (1 grants)

Identification of novel sex-specific factors derived from the human fetus.$7,375
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Vanessa Murphy
SchemeRole
Travelling Award for Research TrainingChief Investigator
Total AmountFunding StartFunding Finish
$7,37520032003
GNo:G0182186

2000 (1 grants)

What causes preterm labour in asthmatic pregnancies? The role of placental 11beta-hydroxysteroid dehydrogenase type 2 and corticotropin releasing hormone$52,905
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Vanessa Murphy
SchemeRole
Dora Lush Postgraduate Research ScholarshipChief Investigator
Total AmountFunding StartFunding Finish
$52,90520002002
GNo:G0181963
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Research Supervision

Number of current supervisions1
Total current UoN Masters EFTSL0.1

For supervisions undertaken at an institution other that the University of Newcastle, details are shown in italics, and the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20112013M Philosophy (Nursing)Co-SupervisorMidwives Knowledge, Understanding and Percieved Role in Caring For Women with Asthma

Past Supervision

YearProgramSupervisor TypeResearch Title
2013PhD (Medicine)Co-SupervisorInvestigation of the Immune Mechanisms in Pregnancy and Asthma Leading to Increased Susceptibility and Disease Severity to Respiratory Virus Infections
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Dr Vanessa Murphy

Work Phone(02) 40420141
Fax(02) 40420046
Email
PositionPostdoctoral Research Fellow
School of Medicine and Public Health
Faculty of Health and Medicine
The University of Newcastle, Australia
Office
HMRI West Wing Level 2,
HMRI,
Other
URL:www.newcastle.edu.au/profile/vanessa-murphy