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Dr Vanessa Murphy

NHMRC Career Development Fellow

School of Medicine and Public Health

Career Summary

Biography

Dr Vanessa Murphy is a postdoctoral research scientist investigating the characteristics, mechanisms and consequences of asthma exacerbations during pregnancy and their health impact on both the mother and the baby. She began in this field full-time in 1999, with her PhD studies on the effects of maternal asthma on placental function and fetal development winning numerous awards, nationally and internationally. In 2004, with a competitive 3 year fellowship from the Hunter Medical Research Institute, she commenced her post-doctoral studies with the Centre for Asthma and Respiratory Diseases, under the supervision of Prof Peter Gibson, where she is continuing to build on her expertise in the area of asthma exacerbations and airway inflammation during pregnancy. Since 2006, Dr Murphy has pursued her research career part-time, and has taken three significant breaks from her career while having children. In 2007 she received her first project grant from the NHMRC, which investigated the mechanisms, characteristics and consequences of viral infections on asthma exacerbations during pregnancy, and she is currently funded by a part-time NHMRC fellowship which was also awarded in 2007. She is involved as an associate investigator on the NHMRC funded “Managing asthma in pregnancy” (MAP) randomised controlled trial, which successfully reduced the rate of severe exacerbations in pregnancy by managing treatment changes with the use of an objective marker of airway inflammation. This resulted in a high impact publication in Lancet in 2011. With pilot funding from HMRI, this study has now been extended to a birth cohort follow-up study, investigating the links between maternal asthma in pregnancy and the development of asthma in childhood, in collaboration with Paediatrician A/Prof Joerg Mattes and Prof Peter Gibson. A further highlight of recent years has been working on an exciting collaboration with the world leader in the field of asthma during pregnancy, Prof Michael Schatz and colleagues in San Diego, USA. Together, we have completed the first systematic review and meta-analysis examining the risks of adverse perinatal outcomes in women with asthma, which has resulted in a publication in the British Journal of Obstetrics and Gynaecology in 2011. Dr Murphy has been invited to write reviews several times, and this year was invited to speak at the European Respiratory Society Conference in Amsterdam in September on the management of asthma during pregnancy, demonstrating her recognition internationally in the field of asthma during pregnancy.

Research Expertise

Vanessa's research expertise is in the area of asthma during pregnancy, covering the effects of asthma on pregnancy outcomes, the management of asthma during pregnancy, and the mechanisms of viral infection in pregnancy. 


Qualifications

  • PhD, University of Newcastle
  • Bachelor of Medicinal Chemistry (Honours), University of Wollongong

Keywords

  • asthma
  • pregnancy

Fields of Research

CodeDescriptionPercentage
110299Cardiorespiratory Medicine and Haematology not elsewhere classified35
160599Policy and Administration not elsewhere classified30
111499Paediatrics and Reproductive Medicine not elsewhere classified35

Professional Experience

UON Appointment

DatesTitleOrganisation / Department
2/03/2015 - 1/03/2019NHMRC Career Development FellowUniversity of Newcastle
School of Medicine and Public Health
Australia
7/02/2008 - 21/03/2008Post Doctoral Research FellowUniversity of Newcastle
School of Medicine and Public Health
Australia

Academic appointment

DatesTitleOrganisation / Department
1/12/2007 - 1/03/2013Australian Part-time Research Fellowship
NHMRC - Early Career Fellowships (Formerly Postdoctoral Training Fellowships)
University of Newcastle
School of Medicine and Public Health
Australia
1/03/2004 - Post Doctoral Research FellowUniversity of Newcastle
School of Medicine and Public Health
Australia

Awards

Research Award

YearAward
2005Young Scientist Sponsorship
European Respiratory Society
2005Ian Potter Foundation Travel Grant
Ian Potter Foundation
2004New Investigator Award
Unknown
2003Elsevier Science New Investigator Award
Unknown
2002Australian Society for Medical Research (ASMR) Research Award
Unknown
2002Best Oral Presentation by a Student
Unknown
2001Medibank Private Student Researcher Award
Unknown
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (3 outputs)

YearCitationAltmetricsLink
2010Murphy VE, Gibson PG, 'Asthma and rhinitis in pregnancy', Allergy Frontiers: Therapy and Prevention, Springer, Berlin 485-497 (2010) [B1]
Co-authorsPeter Gibson
2009Murphy VE, Gibson PG, 'Asthma in pregnancy', Pulmonary Problems in Pregnancy, Humana Press, New York 143-164 (2009) [B1]
DOI10.1007/978-1-59745-445-2
Co-authorsPeter Gibson
2006Murphy VE, Smith R, Giles WB, Clifton VL, 'The role of the mother, placenta, and fetus in the control of fetal growth during human pregnancy', Perinatal Programming: Early Life Determinants of Adult Health & Disease, Taylor & Francis, London 3-16 (2006) [B1]
Co-authorsVicki Clifton, Roger Smith

Journal article (46 outputs)

YearCitationAltmetricsLink
2015Vanders RL, Murphy VE, 'Maternal complications and the management of asthma in pregnancy.', Womens Health (Lond Engl), 11 183-191 (2015)
DOI10.2217/whe.14.69Author URL
2015Vanders RL, Murphy VE, Gibson PG, Hansbro PM, Wark PAB, 'CD8 T cells and dendritic cells: Key players in the attenuated maternal immune response to influenza infection', Journal of Reproductive Immunology, 107 1-9 (2015)

Pregnancy provides a unique challenge for maternal immunity, requiring the ability to tolerate the presence of a semi-allogeneic foetus, and yet still being capable of inducing an immune response against invading pathogens. To achieve this, numerous changes must occur in the activity and function of maternal immune cells throughout the course of pregnancy. Respiratory viruses take advantage of these changes, altering the sensitive balance of maternal immunity, leaving the mother with increased susceptibility to viral infections and increased disease severity. Influenza virus is one of the most common respiratory virus infections during pregnancy, leading to an increased risk of ICU hospitalisations, pneumonia, acute respiratory distress syndrome and even death. Whilst much research has been performed to understand the changes that must take place in maternal immunity during pregnancy, considerable work is still needed to fully comprehend this tremendous feat. To date, few studies have focused on the alterations that occur in maternal immunity during respiratory virus infections. This review highlights the role of dendritic cells (DCs) and CD8 T cells during pregnancy, and the changes that occur in these antiviral cells following influenza virus infections.

DOI10.1016/j.jri.2014.09.051
Co-authorsPeter Gibson, Peter Wark, Philip Hansbro
2015McLaughlin K, Kable A, Ebert L, Murphy VE, 'Barriers preventing Australian midwives from providing antenatal asthma management', British Journal of Midwifery, 23 116-123 (2015)

International guidelines indicate that management of asthma during pregnancy should be multidisciplinary; however, the role of midwives has not been researched. Method: A qualitative descriptive study exploring Australian midwives' current knowledge about asthma in pregnancy and their perceived role in antenatal asthma management was conducted, involving individual semi-structured in-depth interviews with 13 midwives in a tertiary referral hospital. Data were analysed using Morse and Field's four-stage process. Findings: Midwives identified barriers preventing them from providing antenatal asthma management, including: lack of knowledge about asthma in pregnancy; time constraints; women's knowledge about asthma in pregnancy; lack of a clear referral pathway; and lack of accessible asthma management equipment. Barriers were influenced by the institutional context in which the midwives worked. Conclusion: While participants identified barriers preventing them from providing recommended antenatal asthma management, they also suggested that improving their knowledge about asthma in pregnancy and developing a clear referral pathway may be beneficial.

DOI10.12968/bjom.2015.23.2.116
Co-authorsLyn Ebert, Ashley Kable
2015Mandaliya PH, Morten M, Kumar R, James A, Deshpande A, Murphy VE, et al., 'Ventilation inhomogeneities in children with congenital thoracic malformations.', BMC Pulm Med, 15 25 (2015)
DOI10.1186/s12890-015-0023-1Author URL
Co-authorsPeter Gibson
2014Mattes J, Murphy VE, Powell H, Gibson PG, 'Prenatal origins of bronchiolitis: Protective effect of optimised asthma management during pregnancy', Thorax, 69 383-384 (2014) [C1]

Objective Maternal asthma is the most common chronic disease complicating pregnancy and is a risk factor for bronchiolitis in infancy. Recurrent episodes of bronchiolitis are strongly associated with the development of childhood asthma. Methods We conducted a follow-up study of infants born to women with asthma who completed a double-blind randomised controlled trial during pregnancy. In this trial, pregnant women with asthma were assigned to treatment adjustment by an algorithm using clinical symptoms (clinical group) or the fraction of exhaled nitric oxide (FeNO group) and we showed that the FeNO group had significantly lower asthma exacerbation rates in pregnancy. Results 146 infants attended the 12-month follow-up visit. Infants born to mothers from the FeNO group were significantly less likely to have recurrent episodes of bronchiolitis in the first year of life (OR 0.08, 95% CI 0.01 to 0.62; p=0.016) as compared with the clinical group. Conclusions Optimised management of asthma during pregnancy may reduce recurrent episodes of bronchiolitis in infancy, which could potentially modulate the risk to develop or the severity of emerging childhood asthma.

DOI10.1136/thoraxjnl-2013-203388
CitationsScopus - 5Web of Science - 3
Co-authorsPeter Gibson, Joerg Mattes
2014Murphy VE, Mattes J, Powell H, Baines KJ, Gibson PG, 'Respiratory viral infections in pregnant women with asthma are associated with wheezing in the first 12 months of life', Pediatric Allergy and Immunology, 25 151-158 (2014) [C1]

Background: There are few studies investigating the relationship between respiratory viral infection in pregnancy and asthma in the offspring, and none among mothers with asthma. Infants of mothers with asthma are more likely to wheeze and have a higher risk of developing asthma than infants of non-asthmatic mothers. Methods: A prospective cohort study of viral infection in pregnancy was conducted between 2007 and 2009, and a subgroup of infants of mothers with asthma was followed up at 6 and 12 months of age. During common colds, nasal and throat swabs were collected from mothers and respiratory viruses detected by polymerase chain reaction. Respiratory health of infants was assessed by parent-completed questionnaire. Results: Twelve-month-old infants whose mothers had confirmed viral infections in pregnancy (n = 26) reported more frequent wheeze (40% had 4-12 wheeze attacks compared with 0%), sleep disturbed by wheeze (1 night per week or more in 60% vs. 11%), beta agonist treatment for wheeze (27% vs. 0%), prolonged colds (2 wk or longer 31% vs. 0%), more eczema (40% vs. 6.3%), and parent-perceived asthma (32% vs. 0%), compared with infants whose mothers had common colds without laboratory-confirmed viral infection (n = 16). Conclusions: This study demonstrates a relationship between maternal respiratory viral infection in pregnancy and wheezing illness in infants of mothers with asthma. Viral infections are the most common cause of asthma exacerbations in pregnancy, and infants of asthmatic mothers are at increased risk of asthma themselves. Further research is needed to elucidate the mechanisms involved. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

DOI10.1111/pai.12156
CitationsScopus - 2Web of Science - 2
Co-authorsKatherine Baines, Joerg Mattes, Peter Gibson
2014Murphy VE, Schatz M, 'Asthma in pregnancy: A hit for two', European Respiratory Review, 23 64-68 (2014) [C1]

Asthma commonly occurs in pregnant females, and recent data have outlined the risks of adverse perinatal outcomes among this population. There is an increased risk of low birth weight and small for gestational age, particularly among females with moderate-to-severe asthma and exacerbations during pregnancy. There is also an increased risk of preterm birth, especially with oral steroid use, a small but statistically significant increased risk of congenital malformations, particularly of cleft lip with or without cleft palate, and an increased risk of neonatal hospitalisation and death. Active management may reduce these risks, possibly through reductions in exacerbations. Additional reassuring data have been presented for asthma medication use, which support the benefits outweighing the risks of indicated asthma medication use in pregnancy. Viral infections are an important trigger of asthma exacerbations in pregnancy, and recent data provides possible immunological changes that may explain this. Poor medication adherence despite worsening asthma symptoms in pregnancy is a problem which continues to be demonstrated in the literature. Improving asthma control in pregnancy has the potential to improve not only the mother's health but also that of her child. © ERS 2014.

DOI10.1183/09059180.00008313
CitationsScopus - 3
2014Wark PAB, Murphy V, Mattes J, 'The interaction between mother and fetus and the development of allergic asthma', Expert Review of Respiratory Medicine, 8 57-66 (2014) [C1]

The rising prevalence of asthma and atopic disease in industrialized countries in the last 50 years has raised important questions about how and why the disease develops in susceptible populations. Most asthma begins in childhood in association with allergic sensitization and the development of a TH2 phenotype. It is recognized that asthma arises in the context of a complex interaction between genetic factors and the evolving immune system of the infant and the environment to which it is exposed, which now includes its in utero exposure. Early life exposures that lead to allergen sensitization and airway damage, especially in the form of viral respiratory tract infections, may lead to disease induction that commence the process that leads in some to asthma. Asthma models and early life observations suggest that repeated exposure to allergens and viral infection perpetuate a state of chronic airway inflammation leading to a maladaptive innate immune response that fails to resolve, characterized by chronic airway inflammation, airway remodeling and airway hyperresponsiveness. This article will concentrate on the development of asthma in the context of early life and maternal influences, including the effect of asthma on both the fetus and the mother. © 2014 Informa UK Ltd.

DOI10.1586/17476348.2014.848795
CitationsScopus - 3Web of Science - 3
Co-authorsPeter Wark, Joerg Mattes
2014Gunawardhana LP, Baines KJ, Mattes J, Murphy VE, Simpson JL, Gibson PG, 'Differential DNA methylation profiles of infants exposed to maternal asthma during pregnancy', Pediatric Pulmonology, 49 852-862 (2014) [C1]

Background Asthma is a complex disease that involves both genetic factors and environmental exposures. Aberrant epigenetic modifications, such as DNA methylation, may be important in asthma development. Fetal exposure to maternal asthma during critical periods of in utero development may lead to epigenetic alterations that predispose infants to a greater risk of developing asthma themselves. We investigated alterations in the DNA methylation profile of peripheral blood from infants exposed to maternal asthma during pregnancy. Methods Peripheral blood was collected from 12-month-old infants born to women with (n = 25) and without (n = 15) doctor diagnosed asthma during pregnancy. Genomic DNA was extracted, bisulfite converted, and hybridized to Infinium Methylation 27 arrays (Illumina), containing over27,000 CpGs from 14,495 genes. CpG loci in only autosomal genes were classified as differentially methylated at the 99% level (P < 0.01, |DiffScore| > 22 and delta beta >0.06). Results There were 70 CpG loci, corresponding to 67 genes that were significantly differentially methylated. Twelve CpG loci (11 genes) showed greater than 10% comparative difference in DNA methylation, including hyper-methylated loci of FAM181A, MRI1, PIWIL1, CHFR, DEFA1, MRPL28, AURKA, and hypo-methylated loci of NALP1L5, MAP8KIP3, ACAT2, and PM20D1 in maternal asthma. Methylation of MAPK8IP3 was significantly negatively correlated with maternal blood eosinophils (r = -0.38; P = 0.022), maternal eNO (r = -0.44; P = 0.005), and maternal serum total IgE (r = -0.39, P = 0.015). Methylation of AURKA negatively correlated with maternal hemoglobin (r = -0.43; P = 0.008), infants height (r = -0.51; P < 0.001) and weight (r = -0.36; P = 0.021). Methylation of PM20D1 was lower in infants born to mothers with asthma on inhaled corticosteroid treatment. Methylation of PM20D1 was lower and MRI1 was higher in infants born to atopic mothers without asthma. Conclusions In an Australian study population, exposure to maternal asthma during pregnancy is associated with differential methylation profiles of infants' peripheral blood DNA, which may act as risk factors for future asthma development. © 2013 Wiley Periodicals, Inc.

DOI10.1002/ppul.22930
CitationsScopus - 3Web of Science - 2
Co-authorsJodie Simpson, Joerg Mattes, Peter Gibson, Katherine Baines
2014Wang G, Murphy VE, Namazy J, Powell H, Schatz M, Chambers C, et al., 'The risk of maternal and placental complications in pregnant women with asthma: A systematic review and meta-analysis', Journal of Maternal-Fetal and Neonatal Medicine, 27 934-942 (2014) [C1]

Objective: To investigate if maternal asthma is associated with an increased risk of maternal and placental complications in pregnancy. Methods: Electronic databases were searched for the following terms: (asthma or wheeze) and (pregnan* or perinat* or obstet*). Cohort studies published between January 1975 and March 2012 were considered for inclusion. Forty publications met the inclusion criteria, reporting at least one maternal or placental complication in pregnant women with and without asthma. Relative risk (RR) with 95% confidence intervals (CIs) was calculated. Results: Maternal asthma was associated with a significantly increased risk of cesarean section (RR=1.31, 95%CI=[1.22-1.39]), gestational diabetes (RR=1.39, 95%CI=[1.17-1.66]), hemorrhage (antepartum: RR=1.25, 95%CI=[1.10-1.42]; postpartum: RR=1.29, 95%CI=[1.18-1.41]), placenta previa (RR=1.23, 95%CI=[1.07-1.40]), placental abruption (RR=1.29, 95%CI=[1.14-1.47]) and premature rupture of membranes (RR=1.21, 95%CI=1.07-1.37). Moderate to severe asthma significantly increased the risk of cesarean section (RR=1.19, 95%CI=[1.09-1.31]) and gestational diabetes (RR=1.19, 95%CI=[1.06-1.33]) compared to mild asthma. Bronchodilator use was associated with a significantly lowered risk of gestational diabetes (RR=0.64, 95%CI=[0.57-0.72]). Conclusions: Pregnant women with asthma are at increased risk of maternal and placental complications, and women with moderate/severe asthma may be at particular risk. Further studies are required to elucidate whether adequate control of asthma during pregnancy reduces these risks. © 2014 Informa UK Ltd. All rights reserved.

DOI10.3109/14767058.2013.847080
CitationsScopus - 5Web of Science - 3
Co-authorsJohn Attia, Peter Gibson
2013Murphy VE, Powell H, Wark PAB, Gibson PG, 'A Prospective Study of Respiratory Viral Infection in Pregnant Women With and Without Asthma', CHEST, 144 420-427 (2013) [C1]
DOI10.1378/chest.12-1956Author URL
CitationsScopus - 6Web of Science - 2
Co-authorsPeter Gibson, Peter Wark
2013Vanders RL, Gibson PG, Murphy VE, Wark PAB, 'Plasmacytoid Dendritic Cells and CD8 T Cells From PregnantWomen Show Altered Phenotype and Function Following H1N1/09 Infection', JOURNAL OF INFECTIOUS DISEASES, 208 1062-1070 (2013) [C1]
DOI10.1093/infdis/jit296Author URL
CitationsScopus - 4Web of Science - 4
Co-authorsPeter Gibson, Peter Wark
2013Powell H, McCaffery K, Murphy VE, Hensley MJ, Clifton VL, Giles W, Gibson PG, 'Psychosocial Variables Are Related to Future Exacerbation Risk and Perinatal Outcomes in Pregnant Women with Asthma', JOURNAL OF ASTHMA, 50 383-389 (2013) [C1]
DOI10.3109/02770903.2012.757777Author URL
CitationsScopus - 6Web of Science - 5
Co-authorsMichael Hensley, Peter Gibson
2013Namazy JA, Murphy VE, Powell H, Gibson PG, Chambers C, Schatz M, 'Effects of asthma severity, exacerbations and oral corticosteroids on perinatal outcomes', EUROPEAN RESPIRATORY JOURNAL, 41 1082-1090 (2013) [C1]
DOI10.1183/09031936.00195111Author URL
CitationsScopus - 16Web of Science - 13
Co-authorsPeter Gibson
2013Vanders RL, Gibson PG, Wark PAB, Murphy VE, 'Alterations in inflammatory, antiviral and regulatory cytokine responses in peripheral blood mononuclear cells from pregnant women with asthma', RESPIROLOGY, 18 827-833 (2013) [C1]
DOI10.1111/resp.12068Author URL
CitationsScopus - 7Web of Science - 4
Co-authorsPeter Wark, Peter Gibson
2013Murphy VE, Wang G, Namazy JA, Powell H, Gibson PG, Chambers C, Schatz M, 'The risk of congenital malformations, perinatal mortality and neonatal hospitalisation among pregnant women with asthma: a systematic review and meta-analysis', BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 120 812-822 (2013) [C1]
DOI10.1111/1471-0528.12224Author URL
CitationsScopus - 13Web of Science - 12
Co-authorsPeter Gibson
2013Giles W, Murphy V, 'Asthma in pregnancy: a review', Obstetric Medicine: The Medicine of Pregnancy, 6 58-63 (2013) [D1]
DOI10.1258/om.2012.120008Author URL
2012Vanders RL, Wark PA, Murphy VE, Gibson PG, 'Pregnant women have attenuated innate interferon responses to 2009 pandemic influenza a virus subtype H1N1', Journal of Infectious Diseases, 206 646-653 (2012) [C1]
CitationsScopus - 13Web of Science - 12
Co-authorsPeter Wark, Peter Gibson
2012Vanders RL, Gibson PG, Murphy VE, Wark PAB, 'Impaired type I and III interferon response to rhinovirus infection during pregnancy and asthma', Thorax, 67 209-214 (2012) [C1]
CitationsScopus - 28Web of Science - 21
Co-authorsPeter Gibson, Peter Wark
2012McLernon PC, Wood LG, Murphy VE, Hodyl NA, Clifton VL, 'Circulating antioxidant profile of pregnant women with asthma', Clinical Nutrition, 31 99-107 (2012) [C1]
CitationsScopus - 6Web of Science - 5
Co-authorsVicki Clifton, Lisa Wood
2012Murphy VE, Namazy JA, Powell H, Schatz M, Chambers C, Attia JR, Gibson PG, 'Severity of asthma in pregnancy affects perinatal outcomes - Authors' Reply', BJOG - An International Journal of Obstetrics and Gynaecology, 119 508-509 (2012) [C3]
DOI10.1111/j.1471-0528.2011.03258.x
Co-authorsJohn Attia, Peter Gibson
2012McLernon PC, Wood LG, Murphy VE, Hodyl NA, Clifton VL, 'Fatty acid profile of pregnant women with asthma', e-SPEN Journal, 7 e78-e85 (2012) [C1]
DOI10.1016/j.clnme.2012.01.004
Co-authorsLisa Wood, Vicki Clifton
2011Powell GH, Murphy VE, Taylor DR, Hensley MJ, McCaffery K, Giles W, et al., 'Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: A double-blind, randomised controlled trial', The Lancet, 378 983-990 (2011) [C1]
DOI10.1016/s0140-6736(11)60971-9
CitationsScopus - 95Web of Science - 82
Co-authorsMichael Hensley, Peter Gibson
2011Murphy VE, Gibson PG, 'Asthma in pregnancy', Clinics in Chest Medicine, 32 93-110 (2011) [C1]
CitationsScopus - 20Web of Science - 12
Co-authorsPeter Gibson
2011Powell H, McCaffery K, Murphy VE, Hensley MJ, Clifton VL, Giles WB, Gibson PG, 'Psychosocial outcomes are related to asthma control and quality of life in pregnant women with asthma', Journal of Asthma, 48 1032-1040 (2011) [C1]
DOI10.3109/02770903.2011.631239
CitationsScopus - 19Web of Science - 15
Co-authorsPeter Gibson, Michael Hensley
2011Murphy VE, Namazy JA, Powell H, Schatz M, Chambers C, Attia JR, Gibson PG, 'A meta-analysis of adverse perinatal outcomes in women with asthma', BJOG: An International Journal of Obstetrics and Gynaecology, 118 1314-1323 (2011) [C1]
DOI10.1111/j.1471-0528.2011.03055.x
CitationsScopus - 66Web of Science - 56
Co-authorsJohn Attia, Peter Gibson
2010Murphy VE, Clifton VL, Gibson PG, 'The effect of cigarette smoking on asthma control during exacerbations in pregnant women', Thorax, 65 739-744 (2010) [C1]
DOI10.1136/thx.2009.124941
CitationsScopus - 21Web of Science - 17
Co-authorsPeter Gibson, Vicki Clifton
2010Hodyl NA, Wyper HJ, Osei-Kumah A, Scott NM, Murphy VE, Gibson PG, et al., 'Sex-specific associations between cortisol and birth weight in pregnancies complicated by asthma are not due to differential glucocorticoid receptor expression', Thorax, 65 677-683 (2010) [C1]
DOI10.1136/thx.2009.123091
CitationsScopus - 16Web of Science - 12
Co-authorsRoger Smith, Peter Gibson, Vicki Clifton
2010Clifton VL, Hodyl NA, Murphy VE, Giles WB, Baxter RC, Smith R, 'Effect of maternal asthma, inhaled glucocorticoids and cigarette use during pregnancy on the newborn insulin-like growth factor axis', Growth Hormone and IGF Research, 20 39-48 (2010) [C1]
DOI10.1016/j.ghir.2009.07.004
CitationsScopus - 18Web of Science - 15
Co-authorsRoger Smith, Vicki Clifton
2009Scott NM, Hodyl NA, Murphy VE, Osei-Kumah A, Wyper H, Hodgson DM, et al., 'Placental cytokine expression covaries with maternal asthma severity and fetal sex', Journal of Immunology, 182 1411-1420 (2009) [C1]
CitationsScopus - 35Web of Science - 31
Co-authorsRoger Smith, Deborah Hodgson, Vicki Clifton
2008Johnson RF, Rennie N, Murphy VE, Zakar T, Clifton VL, Smith R, 'Expression of glucocorticoid receptor messenger ribonucleic acid transcripts in the human placenta at term', Journal of Clinical Endocrinology & Metabolism, 93 4887-4893 (2008) [C1]
DOI10.1210/jc.2008-1077
CitationsScopus - 21Web of Science - 18
Co-authorsRoger Smith, Vicki Clifton
2008Murphy VE, Gibson PG, 'Premenstrual asthma: Prevalence, cycle-to-cycle variability and relationship to oral contraceptive use and menstrual symptoms', Journal of Asthma, 45 696-704 (2008) [C1]
DOI10.1080/02770900802207279
CitationsScopus - 16Web of Science - 11
Co-authorsPeter Gibson
2007Murphy VE, Fittock RJ, Zarzycki PK, Delahunty MM, Smith R, Clifton VL, 'Metabolism of synthetic steroids by the human placenta', Placenta, 28 39-46 (2007) [C1]
DOI10.1016/j.placenta.2005.12.010
CitationsScopus - 38Web of Science - 30
Co-authorsRoger Smith, Vicki Clifton
2006Murphy VE, Clifton VL, Gibson PG, 'Asthma exacerbations during pregnancy: incidence and association with adverse pregnancy outcomes', Thorax, 61 169-176 (2006) [C1]
DOI10.1136/thx.2005.049718
CitationsScopus - 113Web of Science - 101
Co-authorsVicki Clifton, Peter Gibson
2006Murphy VE, Smith R, Giles WB, Clifton VL, 'Endocrine regulation of human fetal growth: The role of the mother, placenta, and fetus', Endocrine Reviews, 27 141-169 (2006) [C1]
DOI10.1210/er.2005-0011
CitationsScopus - 221Web of Science - 189
Co-authorsVicki Clifton, Roger Smith
2006Murphy VE, Johnson RF, Wang YC, Akinsanya K, Gibson PG, Smith R, Clifton VL, 'Proteomic study of plasma proteins in pregnant women with asthma', Respirology, 11 41-48 (2006) [C1]
DOI10.1111/j.1440-1843.2006.00782.x
CitationsScopus - 19Web of Science - 18
Co-authorsPeter Gibson, Vicki Clifton, Roger Smith
2006Clifton VL, Rennie N, Murphy VE, 'Effect of inhaled glucocorticoid treatment on placental 11 beta-hydroxysteroid dehydrogenase type 2 activity and neonatal birthweight in pregnancies complicated by asthma', Australian and New Zealand Journal of Obstetrics and Gynaecology, 46 136-140 (2006) [C1]
DOI10.1111/j.1479-828X.2006.00543.x
CitationsScopus - 39Web of Science - 31
Co-authorsVicki Clifton
2005Murphy VE, Gibson PG, Smith R, Clifton VL, 'Asthma during pregnancy: mechanisms and treatment implications', European Respiratory Journal, 25 731-750 (2005) [C1]
DOI10.1183/09031936.05.00085704
CitationsScopus - 79Web of Science - 65
Co-authorsRoger Smith, Peter Gibson, Vicki Clifton
2005Murphy VE, Gibson PG, Talbot PI, Kessell CG, Clifton VL, 'Asthma self-management skills and the use of asthma education during pregnancy', European Respiratory Journal, 26 435-441 (2005) [C1]
DOI10.1183/09031936.05.00135604
CitationsScopus - 43Web of Science - 32
Co-authorsVicki Clifton, Peter Gibson
2005Murphy VE, Johnson RF, Wang Y-C, Akinsanya K, Gibson PG, Smith R, Clifton VL, 'The Effect of Maternal Asthma on Placental and Cord Blood Protein Profiles', Society for Gynecological Investigation Journal, 12 349-355 (2005) [C1]
DOI10.1016/j.jsgi.2005.01.024
CitationsScopus - 16Web of Science - 15
Co-authorsVicki Clifton, Peter Gibson, Roger Smith
2005Murphy VE, Gibson PG, Talbot PI, Clifton VL, 'Severe asthma exacerbations during pregnancy', Obstetrics and Gynecology, 106 1046-1054 (2005) [C1]
Co-authorsVicki Clifton, Peter Gibson
2004Clifton VL, Murphy VE, 'Maternal Asthma as a Model for Examining Fetal Sex-specific Effects on Maternal Physiology and Placental Mechanisms that Regulate Human Fetal Growth', Placenta, 18 S45-S52 (2004) [C1]
DOI10.1016/j.placenta.2004.01.004
CitationsWeb of Science - 61
Co-authorsVicki Clifton
2003Murphy VE, Clifton VL, 'Alterations in human placental 11 beta-hydroxysteroid dehydrogenase type 1 and 2 with gestational age and labour', Placenta, 24 739-744 (2003) [C1]
DOI10.1016/S0143-4004(03)00103-6
CitationsScopus - 62Web of Science - 58
Co-authorsVicki Clifton
2003Murphy VE, Gibson PG, Giles WB, Zakar T, Smith R, Bisits AM, et al., 'Maternal Asthma Is Associated with Reduced Female Fetal Growth', American Journal of Respiratory & Critical Care Medicine, 168 1317-1323 (2003) [C1]
DOI10.1164/rccm.200303-374OC
CitationsScopus - 125Web of Science - 116
Co-authorsPeter Gibson, Roger Smith, Vicki Clifton
2002Murphy VE, Zakar T, Smith R, Giles WB, Gibson PG, Clifton VL, 'Reduced 11 -Hydroxysteroid Dehydrogenase Type 2 Activity Is Associated with Decreased Birth Weight Centile in Pregnancies Complicated by Asthma', The Journal of Clinical Endocrinology & Metabolism, 87(4) 1660-1668 (2002) [C1]
CitationsScopus - 90Web of Science - 86
Co-authorsPeter Gibson, Roger Smith, Vicki Clifton
2000Clifton VL, Qing G, Murphy VE, Schwartz J, Madsen GM, Smith R, 'Localization and Characterization of Urocortin during Human Pregancy', Placenta, 21 782-788 (2000) [C1]
CitationsScopus - 44Web of Science - 39
Co-authorsRoger Smith, Vicki Clifton, Gemma Madsen
Show 43 more journal articles

Conference (61 outputs)

YearCitationAltmetricsLink
2013Mattes J, Murphy V, Powell H, Gibson P, 'THE EFFECT OF BETTER ASTHMA CONTROL IN PREGNANCY ON WHEEZY ILLNESSES IN INFANCY', RESPIROLOGY (2013) [E3]
Author URL
CitationsWeb of Science - 1
Co-authorsJoerg Mattes, Peter Gibson
2013Forbes RL, Gibson PG, Murphy VE, Wark PA, 'H1N1PDM09 ALTERS MATERNAL IMMUNITY DURING PREGNANCY', RESPIROLOGY (2013) [E3]
Author URL
Co-authorsPeter Wark, Peter Gibson
2013Gunawardhana LP, Baines KJ, Mattes J, Murphy VE, Simpson JL, Gibson PG, 'EPIGENETIC ALTERATIONS IN INFANTS ASSOCIATED WITH MATERNAL ASTHMA DURING PREGNANCY', RESPIROLOGY (2013) [E3]
Author URL
Co-authorsJoerg Mattes, Peter Gibson, Jodie Simpson, Katherine Baines
2012Powell HG, McCaffery K, Murphy VE, Giles W, Clifton VL, Hensley MJ, Gibson PG, 'Psychosocial outcomes are related to future exacerbation risk and perinatal outcomes in pregnant women with asthma', Respirology, Canberra, ACT (2012) [E3]
CitationsWeb of Science - 1
Co-authorsVicki Clifton, Peter Gibson, Michael Hensley
2011Clifton VL, McLernon PC, Wood LG, Murphy VE, Stark MJ, Hodyl NA, 'What do women eat during pregnancy?', Journal of Developmental Origins of Health and Disease, Portland, Oregon (2011) [E3]
Co-authorsLisa Wood
2011Namazy JA, Murphy VE, Powell H, Gibson PG, Chambers C, Schatz M, 'Effects of asthma severity and medication use on prematurity and intrauterine growth: A meta analysis from published data', Journal of Allergy and Clinical Immunology, San Francisco, CA (2011) [E3]
Co-authorsPeter Gibson
2011Clifton V, McLernon P, Wood LG, Murphy VE, Hodyl N, 'What do pregnant women eat?', Placenta: Abstracts of the IFPA Meeting 2011, Geilo, Norway (2011) [E3]
Co-authorsLisa Wood
2011Gibson PG, Powell H, Giles W, Clifton V, Hensley MJ, Taylor DR, et al., 'Asthma exacerbations during pregnancy are reduced by inflammometry (FENO) guided asthma management: A randomised controlled trial', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
Co-authorsPeter Gibson, Michael Hensley
2011McLaughlin KM, Mattes J, Murphy VE, Steel KR, Powell H, Gibson PG, 'The Growing Into Asthma (GIA) Study: Need for improved management of respiratory illnesses in early life', PSANZ 2011 15th Annual Congress: Poster Abstracts, Hobart, TAS (2011) [E3]
Co-authorsJoerg Mattes, Peter Gibson
2011Vanders RL, Gibson PG, Murphy VE, Wark PA, 'Reduced antiviral interferons during pregnancy explains susceptibility to influenza virus infection', Respirology, Perth, WA (2011) [E3]
Co-authorsPeter Wark, Peter Gibson
2011Gunawardhana LP, Baines KJ, Simpson JL, Mattes J, Murphy VE, Gibson PG, 'Maternal asthma is associated with alterations in DNA methylation profile of peripheral blood of infants', Respirology, Perth, WA (2011) [E3]
Co-authorsKatherine Baines, Jodie Simpson, Peter Gibson, Joerg Mattes
2011Mattes J, Murphy VE, McLaughlin KM, Steel KR, Powell H, Gibson PG, 'Are maternal asthma exacerbations during pregnancy related to impaired infant growth in the first six months of life?', Respirology, Perth, WA (2011) [E3]
Co-authorsPeter Gibson, Joerg Mattes
2010Murphy VE, Namazy JA, Powell GH, Gibson PG, Chambers C, Attia JR, Schatz M, 'A meta-analysis of adverse perinatal outcomes in asthmatic women: Effect of asthma on placental and neonatal outcomes', American Journal of Respiratory and Critical Care Medicine, New Orleans (2010) [E3]
Co-authorsJohn Attia, Peter Gibson
2010Namazy JA, Murphy VE, Powell HG, Gibson PG, Chambers CD, Schatz M, 'Congenital anomalies in asthmatic women using corticosteroids during pregnancy: A meta analysis from published data', Birth Defects Research (Part A), Louisville, KT (2010) [E3]
Co-authorsPeter Gibson
2010McLernon PC, Murphy VE, Wood LG, Dekker GA, Hodyl NA, Clifton VL, 'Maternal plasma circulating levels of omega (n)3 long chain polyunsaturated fatty acids, eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA) are associated with fetal growth measures', The Endocrine Society of Australia Annual Scientific Meeting Proceedings and Abstract Book, Sydney (2010) [E3]
Co-authorsLisa Wood, Vicki Clifton
2010Namazy JA, Murphy VE, Powell HG, Gibson PG, Chambers C, Schatz M, 'Adverse perinatal outcomes in asthmatic women: A meta analysis from published data', Journal of Allergy and Clinical Immunology, New Orleans, LA (2010) [E3]
Co-authorsPeter Gibson
2010McLernon PC, Wood LG, Murphy VE, Dekker GA, Clifton VL, 'Maternal circulating levels of omega (N)3 long chain polyunsaturated fatty acids, eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaunoic acid (DHA) during early pregnancy are associated with detal growth meaures in later pregnancy', Placenta, Kumamoto, Japan (2010) [E3]
Co-authorsVicki Clifton, Lisa Wood
2010Vanders RL, Gibson PG, Murphy VE, Wark PA, 'Reduced anti-viral responses: Why pregnant women have increased susceptibility to respiratory virus infection', American Journal of Respiratory and Critical Care Medicine, New Orleans, LO (2010) [E3]
Co-authorsPeter Gibson, Peter Wark
2010Vanders RL, Gibson PG, Murphy VE, Wark PA, 'Reduced anti-viral responses: Why pregnant women have increased susceptiblty to respiratory virus infection', Respirology, Brisbane, QLD (2010) [E3]
Co-authorsPeter Wark, Peter Gibson
2010Murphy VE, Namazy J, Powell GH, Gibson PG, Chambers C, Attia JR, Schatz M, 'A meta-analysis of adverse perinatal outcomes in asthmatic women: Effect of asthma on maternal and neonatal outcomes', Respirology, Brisbane, QLD (2010) [E3]
Co-authorsJohn Attia, Peter Gibson
2010Murphy VE, Namazy J, Powell GH, Schatz M, Chambers C, Attia JR, Gibson PG, 'A meta-analysis of adverse perinatal outcomes in asthmatic women: Effect of asthma on size at birth and timing of birth', Respirology, Brisbane, QLD (2010) [E3]
Co-authorsPeter Gibson, John Attia
2009Murphy VE, Clifton VL, Gibson PG, 'The effect of cigarette smoking on asthma control and exacerbations in pregnant women', Respirology, Darwin, NT (2009) [E3]
DOI10.1111/j.1440-1843.2009.01503_1.x
Co-authorsPeter Gibson
2009Powell H, Murphy VE, Gibson PG, 'The relationship between feno and atopic status in pregnant women with asthma', Respirology, Darwin, NT (2009) [E3]
DOI10.1111/j.1440-1843.2009.01503_1.x
Co-authorsPeter Gibson
2009McLaughlin KM, Murphy VE, McCaffery K, Powell H, Clifton VL, Giles W, et al., 'The relationship between patient perceived risk of inhaled corticosteroids in pregnancy and medication adherence', Respirology, Darwin, NT (2009) [E3]
Co-authorsPeter Gibson, Michael Hensley
2008Murphy VE, Clifton VL, Gibson PG, 'Characterization of asthma control and airway inflammation during exacerbations in pregnancy', American Journal of Respiratory and Critical Care Medicine, Toronto, ONT (2008) [E3]
Co-authorsPeter Gibson, Vicki Clifton
2008McLernon PC, Wood LG, Murphy VE, Dekker GA, Clifton VL, 'Maternal circulating antioxidant levels in pregnancies complicated by asthma', 51st Annual Scientific Meeting of the Endocrine Society of Australia and Society of Reproductive Biology: Meeting Proceedings and Abstract Book, Melbourne, VIC (2008) [E3]
Co-authorsLisa Wood
2008Hodyl N, Wyper H, Scott NM, Osei-Kumah A, Murphy VE, Smith R, Clifton VL, 'Relationship between placental glucocorticoid receptor expression and fetal growth in pregnancies complicated by asthma', 51st Annual Scientific Meeting of the Endocrine Society of Australia and Society of Reproductive Biology: Meeting Proceedings and Abstract Book, Melbourne, VIC (2008) [E3]
Co-authorsRoger Smith, Vicki Clifton
2008McLaughlin K, Murphy VE, McCaffery K, Powell H, Clifton V, Giles W, et al., 'The relationship between patient perceived risk of inhaled corticosteroids in pregnancy and medication adherence', Australian Asthma Conference 2008: Conference Program & Abstract Book, Sydney, NSW (2008) [E3]
Co-authorsPeter Gibson
2007Murphy VE, Clifton VL, Gibson PG, 'Fractional exhaled nitric oxide (FENO) in pregnant women with and without asthma', Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3]
Co-authorsPeter Gibson, Vicki Clifton
2006Micallef MA, Garg ML, Wood LG, Murphy VE, Clifton VL, 'Dietry intake of long chain n-3 polyunsaturated fatty acids in adults with asthma', Asia Pacific Journal of Clinical Nutrition, Sydney, New South Wales (2006) [E3]
Co-authorsManohar Garg, Vicki Clifton, Lisa Wood
2006Scott NM, Wyper HJ, Osei-Kumah A, Smith R, Murphy VE, Clifton VL, 'Sex specific differences in placental cytokine expression and their relationship to fetal glucocorticoid exposure', Journal of the Society for Gynecologic Investigation. Scientific Program and Abstracts 53rd Annual Meeting, Toronto, Ontario (2006) [E3]
Co-authorsVicki Clifton, Roger Smith
2005Murphy VE, Clifton VL, Talbot PI, Gibson PG, 'Severe asthma exacerbations during pregnancy', Perinatal Society of Australia and New Zealand 9th Annual Congress, Adelaide, 13-16 March, 2005, Adelaide (2005) [E3]
CitationsWeb of Science - 83
Co-authorsPeter Gibson, Vicki Clifton
2005Murphy VE, Clifton VL, Gibson PG, 'Asthma exacerbations during pregnancy are associated with low birth weight', European Respiratory Journal, Switzerland (2005) [C3]
Co-authorsPeter Gibson, Vicki Clifton
2005Wynne OL, Clifton VL, Murphy VE, Hodyl NA, Krivanek K, Smith D, et al., 'The Effects of Prenatal Endotoxin Exposure on Placental 11-HSD2 Activity and the Developing HPA Axis in the Fischer 344 Rat', Australian Neuroscience Society: Proceedings of the 25th Annual, Perth, Australia (2005) [E3]
Co-authorsVicki Clifton, Deborah Hodgson, Philip Hansbro, Olivia Wynne
2005Murphy VE, Talbot PI, Clifton VL, Gibson PG, 'Severe asthma exacerbations during pregnancy', American Journal of Respiratory and Critical Care, New York (2005) [C3]
Co-authorsPeter Gibson, Vicki Clifton
2005Murphy VE, Clifton VL, Talbot PI, Gibson PG, 'Self-management education for pregnant women with asthma', American Journal of Respiratory and Critical Care Medicine, New York (2005) [C3]
Co-authorsVicki Clifton, Peter Gibson
2005Gibson PG, Giles WB, Zakar T, Smith R, Kessell CG, Clifton VL, Murphy VE, 'Inflammatory factors have sex-specified effects on fetal growth in humans', Ceska Gynekologie, Czech Republic (2005) [C3]
Co-authorsPeter Gibson, Roger Smith, Vicki Clifton
2005Murphy VE, Talbot PI, Clifton VL, Gibson PG, 'Severe asthma exacerbations during pregnancy', Respirology, Philadelphia (2005) [C3]
DOI10.1097/01.AOG.0000185281.21716.02
Co-authorsPeter Gibson, Vicki Clifton
2005Murphy VE, Clifton VL, Talbot PI, Gibson PG, 'Self-management education for pregnant women with asthma. Thoracic Society of Australia and New Zealand Annual Scientific Meeting, Perth, 18-23 March, 2005', Respirology, - (2005) [C3]
Co-authorsPeter Gibson, Vicki Clifton
2005Murphy VE, Talbot PI, Gibson PG, 'The prevalence and cycle to cycle variability of premenstrual asthma', Respirology, Hoboken (2005) [C1]
DOI10.1111/j.1440-1843.2005.00663.x-i1
Co-authorsPeter Gibson
2005Fittock R, Murphy VE, Smith R, Zarzycki PK, Clifton VL, 'Metabolism of synthetic glucocorticoids used for the treatment of asthma by placental 11beta-hydoxysteroid dehydrogenase 2', Endocrine Society of Australia Annual Scientific Meeting, Adelaide, 22-25 Sept, 2002, Adelaide (2005) [E3]
Co-authorsRoger Smith, Vicki Clifton
2005Clifton VL, Murphy VE, Gibson PG, Smith R, Giles WB, Scott N, 'Gender specific differences in response to changes in glucocorticoid concentration in the human fetus: Relationship to birthweight', PEDIATRIC RESEARCH, Toronto, CANADA (2005)
Author URL
Co-authorsPeter Gibson, Roger Smith
2004Clifton VL, Murphy VE, Osei-Kumah A, Giles WB, Smith R, Gibson PG, 'Gender specific mechanisms of human fetal cortisol metabolism and immunity.', JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, Houston, TX (2004)
Author URL
Co-authorsRoger Smith, Peter Gibson
2004Gibson PG, Murphy VE, Kessell CG, Talbot PI, Giles WB, Smith R, Clifton VL, 'Effect of fetal gender on maternal athsma during pregnancy', American Journal of Respiratory Care, Not Known (2004) [C3]
Co-authorsRoger Smith, Peter Gibson, Vicki Clifton
2004Talbot PI, Murphy VE, Kessell CG, Giles WB, Smith R, Gibson PG, Clifton VL, 'Effect of fetal gender on maternal asthma during pregnancy', Respirology, Australia (2004) [C3]
Co-authorsRoger Smith, Peter Gibson, Vicki Clifton
2004Clifton VL, Murphy VE, Giles WB, 'Gender specific mechanisms of human fetal cortisol metabolism and immunity', Reproductive Sciences, United States (2004) [C3]
Co-authorsVicki Clifton
2004Johnson RF, Mitchell CM, Murphy VE, Wang Y, Akinsanya K, Smith R, Zakar T, 'Proteomic analyss of proteins in the human amnion during late gestation and labor', reproductive Sciences, United States (2004) [C3]
Co-authorsRoger Smith
2004Murphy VE, Kessell CG, Talbot PI, Gibson PG, Clifton VL, 'Asthma education, lung function and inflammation in pregnant women: relation to birth weight', 8th Annual Conference of the Perinatal Society of Australia and New Zealand, Sydney, 15-19 March, 2004, Sydney (2004) [E3]
Co-authorsVicki Clifton, Peter Gibson
2004Clifton VL, Murphy VE, Gibson PG, 'Gender specific growth mechanisms in the human fetus', 8th Annual Conference of the Perinatal Society of Australia and New Zealand, Sydney, 15-19 March, 2004, Sydney (2004) [E3]
Co-authorsPeter Gibson, Vicki Clifton
2004Delahunty M, Fittock R, Murphy VE, Smith R, Zarzycki PK, Clifton VL, 'Metabolism of synthetic glucocortcoids used for the treatment of asthma by the human placenta', Conference of the Perinatal Society of Australia and New Zealand, Sydney, 15-19 March, 2004, Sydney (2004) [E3]
Co-authorsVicki Clifton, Roger Smith
2004Murphy VE, Gibson PG, Kessell CG, Clifton VL, 'Asthma self-management education for pregnant women delivered in an antenatal clinic setting', Perinatal Scoiety of Australian and New Zealand 9th annual Congress, Adelaide, 13-16 March, Adealide (2004) [E3]
Co-authorsPeter Gibson, Vicki Clifton
2003Murphy VE, Gibson PG, Giles WB, Smith R, Clifton VL, 'A novel model for examining fetal growth restriction in human pregnancy', Reproductive Sciences, United States (2003) [C3]
Co-authorsVicki Clifton, Roger Smith, Peter Gibson
2003Murphy VE, Johnson RF, Wang Y, Akinsanya K, Gibson PG, Smith R, Clifton VL, 'A proteomic analysis of maternal plasma, umbilical cord plasma and placenta in asthmatic and non-asthmatic pregnancies', Australian Society for Medical Research, National Scientific Conference, Glenelg, 22-24 Nov, 2003, Not Known (2003) [E3]
Co-authorsVicki Clifton, Roger Smith, Peter Gibson
2003Murphy VE, Gibson PG, Giles WB, Smith R, Clifton VL, 'The effect of fetal gender on maternal inflammation and lung function in asthmatic pregnancies', Endocrine Society of Australia Annual Meeting, Melbourne 14-17 Sept, 2003, Melbourne (2003) [E3]
Co-authorsVicki Clifton, Roger Smith, Peter Gibson
2003Scott NM, Osei-Kumah A, Murphy VE, Clifton VL, 'Are female fetuses more sensitive to the effects of inflammation than male fetuses?', Endocrine Society of Australian Annual Scientific Meeting, Melbourne, 14-17 Sept, 2003, Melbourne (2003) [E3]
Co-authorsVicki Clifton
2003Murphy VE, Gibson PG, Giles WB, Smith R, Zarzycki PK, 'Placental and maternal inflammatory pathways in pregnancies complicated by asthma', Placenta, United Kingdom (2003) [C3]
Co-authorsPeter Gibson, Roger Smith
2003Clifton VL, Fittock R, Murphy VE, Smith R, 'Metabolism of semi-synthetic glucocorticoids by the human placenta', Placenta, United Kingdom (2003) [C3]
Co-authorsVicki Clifton, Roger Smith
2002Murphy VE, Zakar T, Smith R, Giles WB, Kessell CG, Clifton VL, 'Maternal asthma affects fetal growth in a gender specific manner and is associated with reduced placental 11beta-HSD2 activity and altered sensitivity to cortisol', Reproductive Sciences, United States (2002) [C3]
Co-authorsRoger Smith, Vicki Clifton
2002Murphy VE, Gibson PG, Giles WB, Zakar T, Smith R, Kessell CG, Clifton VL, 'Sex-specific changes in placental function and fetal growth and development in pregnancies complicated by ashtma', Endocrine Society of Australia Annual Scientific Meeting, Adelaide, 22-25 Sept, 2002, Adelaide (2002) [E3]
Co-authorsPeter Gibson, Roger Smith, Vicki Clifton
2001Murphy VE, Zakar T, Gibson PG, Giles WB, Smith R, Clifton VL, 'Pleacental 11beta-HSD2 activity in asthmatic women', Reproductive sciences, United States (2001) [C3]
Co-authorsPeter Gibson, Roger Smith, Vicki Clifton
2001Murphy VE, Zakar T, Smith R, Giles WB, Gibson PG, Clifton VL, 'A potential mechnism for growth retardation in pregnancies complicated by asthma', Endocrine Society of Australia Annual Scientific Meeting, Gold Coast, 9-12 Sept, 2001, Gold Coast (2001) [E3]
Co-authorsPeter Gibson, Roger Smith, Vicki Clifton
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Grants and Funding

Summary

Number of grants34
Total funding$4,576,493

Click on a grant title below to expand the full details for that specific grant.


20157 grants / $1,598,988

The effect of asthma control during pregnancy on markers of airways inflammation and lung function in the offspring$1,083,354

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamProfessor Joerg Mattes, Doctor Vanessa Murphy, Professor Peter Sly, Doctor Adam Collison, Professor Paul Robinson
SchemeProject Grant
RoleInvestigator
Funding Start2015
Funding Finish2015
GNoG1400050
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Optimising asthma management in pregnancy for optimal infant health$411,768

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamDoctor Vanessa Murphy
SchemeCareer Development Fellowships
RoleLead
Funding Start2015
Funding Finish2015
GNoG1400195
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

DVC(RI) Research Support for Career Development Fellow (CDF15)$60,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamDoctor Vanessa Murphy
SchemeSpecial Project Grant
RoleLead
Funding Start2015
Funding Finish2015
GNoG1500323
Type Of FundingInternal
CategoryINTE
UONY

Viral infections in the BLT cohort in the first year of life$19,000

Funding body: John Hunter Hospital Charitable Trust Fund

Funding bodyJohn Hunter Hospital Charitable Trust Fund
Project TeamProfessor Joerg Mattes, Doctor Vanessa Murphy, Doctor Adam Collison
SchemeResearch Grant
RoleInvestigator
Funding Start2015
Funding Finish2015
GNoG1500671
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Lung function in early life for children with high asthma risk$17,048

Funding body: Rebecca L Cooper Medical Research Foundation Ltd

Funding bodyRebecca L Cooper Medical Research Foundation Ltd
Project TeamProfessor Joerg Mattes, Doctor Vanessa Murphy, Doctor Adam Collison
SchemeResearch Grant
RoleInvestigator
Funding Start2015
Funding Finish2015
GNoG1500704
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Lillian Roxon Asthma Australia Travel Grant$6,818

Funding body: Asthma Australia

Funding bodyAsthma Australia
Project TeamDoctor Vanessa Murphy
SchemeLillian Roxon Asthma Australia Travel Grant
RoleLead
Funding Start2015
Funding Finish2015
GNoG1500772
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Perinatal Society of Australia and NewZealand, Melbourne Australia, 18-22 April 2015$1,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding bodyUniversity of Newcastle - Faculty of Health and Medicine
Project TeamDoctor Vanessa Murphy
SchemeTravel Grant
RoleLead
Funding Start2015
Funding Finish2016
GNoG1500537
Type Of FundingInternal
CategoryINTE
UONY

20142 grants / $1,649,904

The Breathing for Life Trial $1,647,904

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamDoctor Vanessa Murphy, Conjoint Professor Peter Gibson, Emeritus Professor Michael Hensley, Professor Joerg Mattes, Professor Warwick Giles, Professor Michael Peek, Associate Professor Andrew Bisits, Associate Professor Leonie Callaway, Dr Kirsten McCaffery, Dr Helen Barrett
SchemeProject Grant
RoleLead
Funding Start2014
Funding Finish2014
GNoG1300106
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

European Respiratory Society International Congress, Munich Germany, 6 - 10 September 2014$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding bodyUniversity of Newcastle - Faculty of Health and Medicine
Project TeamDoctor Vanessa Murphy
SchemeTravel Grant
RoleLead
Funding Start2014
Funding Finish2014
GNoG1400839
Type Of FundingInternal
CategoryINTE
UONY

20134 grants / $73,810

Impact of fractional exhaled nitric oxide-based management of pregnancies with asthma on perinatal and infant outcomes $23,810

Funding body: John Hunter Hospital Charitable Trust Fund

Funding bodyJohn Hunter Hospital Charitable Trust Fund
Project TeamDoctor Vanessa Murphy, Emeritus Professor Michael Hensley
SchemeResearch Grant
RoleLead
Funding Start2013
Funding Finish2013
GNoG1300782
Type Of FundingOther Public Sector - State
Category2OPS
UONY

Inflammometry-based management of asthma in pregnancy for the prevention of preterm birth: the iMAP study$20,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamDoctor Vanessa Murphy, Conjoint Professor Peter Gibson, Emeritus Professor Michael Hensley, Conjoint Professor Warwick Giles, Conjoint Associate Professor Andrew Bisits, Dr Kirsten McCaffery, Professor Paul Colditz, Professor Michael Peek
SchemeNear Miss Grant
RoleLead
Funding Start2013
Funding Finish2013
GNoG1300477
Type Of FundingInternal
CategoryINTE
UONY

Inflammometry-based management of asthma in pregnancy for the prevention of preterm birth: the iMAP study$20,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamDoctor Vanessa Murphy
SchemeNear Miss
RoleLead
Funding Start2013
Funding Finish2013
GNoG1300695
Type Of FundingInternal
CategoryINTE
UONY

Effect of better asthma management in pregnancy on antiviral responses, atopy and airways inflammation in early childhood$10,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamProfessor Joerg Mattes, Conjoint Professor Peter Gibson, Doctor Vanessa Murphy
SchemeNear Miss Grant
RoleInvestigator
Funding Start2013
Funding Finish2013
GNoG1300476
Type Of FundingInternal
CategoryINTE
UONY

20122 grants / $58,076

Body plethysmograph respiratory function system$33,076

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamConjoint Professor Peter Gibson, Conjoint Professor Peter Wark, Associate Professor Lisa Wood, Associate Professor Jodie Simpson, Doctor Katie Baines, Doctor Vanessa Murphy, Doctor Jeffrey Pretto, Emeritus Professor Michael Hensley, Ms Jenny Mackney
SchemeEquipment Grant
RoleInvestigator
Funding Start2012
Funding Finish2012
GNoG1100973
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

The Growing into Asthma Study: Wheezing prevalence and markers of airways inflammation in preschoolers born to mothers in asthma exacerbations in pregnancy$25,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamProfessor Joerg Mattes, Conjoint Professor Peter Gibson, Emeritus Professor Michael Hensley, Conjoint Associate Professor Bruce Whitehead, Doctor Vanessa Murphy
SchemeProject Grant
RoleInvestigator
Funding Start2012
Funding Finish2012
GNoG1200662
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

20111 grants / $10,000

Lung Function (Spirometry) testing and sputum induction equipment - establishing 3 new clinical workstations. Medgraphics CPFS/d USB spirometer with breezesuite software (x3). Laptop computer (x3). Ul$10,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamConjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Doctor Katie Baines, Conjoint Professor Peter Wark, Doctor Vanessa Murphy
SchemeEquipment Grant
RoleInvestigator
Funding Start2011
Funding Finish2011
GNoG1100038
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

20101 grants / $34,000

Real time PCR machine (Mastercycler ep realplex2 from Epprndorf) $34,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamAssociate Professor Jodie Simpson, Conjoint Professor Peter Gibson, Conjoint Professor Peter Wark, Associate Professor Lisa Wood, Doctor Vanessa Murphy, Doctor Robert Scott, Doctor Katie Baines
SchemeEquipment Grant
RoleInvestigator
Funding Start2010
Funding Finish2010
GNoG1000056
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

20092 grants / $38,300

Growing into asthma: A birth cohort study to investigate the prenatal and development origins of asthma$24,800

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamDoctor Vanessa Murphy, Professor Joerg Mattes, Conjoint Professor Peter Gibson
SchemeProject Grant
RoleLead
Funding Start2009
Funding Finish2009
GNoG0189802
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

Growing into asthma: a birth cohort study to investigate the prenatal and development origins of asthma$13,500

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamDoctor Vanessa Murphy, Professor Joerg Mattes, Conjoint Professor Peter Gibson
SchemeProject Grant
RoleLead
Funding Start2009
Funding Finish2009
GNoG0190487
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

20082 grants / $39,000

Becton Dickinson high throughout sampler for the FACSCanto II cytometry system$35,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamConjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Doctor Vanessa Murphy, Professor Phil Hansbro
SchemeEquipment Grant
RoleInvestigator
Funding Start2008
Funding Finish2008
GNoG0188547
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

PULSE Education Prize$4,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamDoctor Vanessa Murphy
SchemePULSE Education Prize
RoleLead
Funding Start2008
Funding Finish2008
GNoG0188538
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

20076 grants / $672,250

Viral infection and exacerbations of asthma during pregnancy: characteristics, mechanisms and consequences$447,750

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamDoctor Vanessa Murphy
SchemeProject Grant
RoleLead
Funding Start2007
Funding Finish2007
GNoG0186434
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Viral infection and exacerbations of asthma during pregnancy: characteristics, mechanisms and consequences$137,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamDoctor Vanessa Murphy
SchemeTraining (Postdoctoral) Fellowships - Australian Part-time Research Fellowship
RoleLead
Funding Start2007
Funding Finish2007
GNoG0186778
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Nitric Oxide Monitoring System (NIOX)$45,000

Funding body: NHMRC (National Health & Medical Research Council)

Hewlett Packard 7890 series gas chromatograph with accessories$20,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamAssociate Professor Lisa Wood, Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Doctor Vanessa Murphy, Laureate Professor Paul Foster, Professor Phil Hansbro, Conjoint Associate Professor Vicki Clifton, Professor Clare Collins, Conjoint Professor Wayne Smith, Professor John Attia
SchemeEquipment Grant
RoleInvestigator
Funding Start2007
Funding Finish2007
GNoG0188191
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

Class II biohazard containment hood and carbon dioxide cell culture incubator$20,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamConjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Doctor Vanessa Murphy, Associate Professor Lisa Wood, Laureate Professor Paul Foster, Professor Phil Hansbro
SchemeEquipment Grant
RoleInvestigator
Funding Start2007
Funding Finish2007
GNoG0188192
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

American Thoracic Society Conference, San Francisco, 18/5/2007 - 23/5/2007$2,500

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamDoctor Vanessa Murphy
SchemeTravel Grant
RoleLead
Funding Start2007
Funding Finish2007
GNoG0187767
Type Of FundingInternal
CategoryINTE
UONY

20062 grants / $69,100

The relationship between eosinophilic inflammation, viral infection and severe asthma exacerbations during pregnancy$50,000

Funding body: Asthma Foundation of New South Wales

Funding bodyAsthma Foundation of New South Wales
Project TeamDoctor Vanessa Murphy, Conjoint Associate Professor Vicki Clifton, Emeritus Professor Michael Hensley, Conjoint Professor Warwick Giles, Conjoint Professor Peter Gibson
SchemeResearch Grant
RoleLead
Funding Start2006
Funding Finish2006
GNoG0186029
Type Of FundingDonation - Aust Non Government
Category3AFD
UONY

Viral infections and asthma exacerbations during pregnancy: characteristics, mechanisms and consequences$19,100

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamDoctor Vanessa Murphy, Conjoint Associate Professor Vicki Clifton, Emeritus Professor Michael Hensley, Conjoint Professor Warwick Giles
SchemeNear Miss Grant
RoleLead
Funding Start2006
Funding Finish2006
GNoG0186061
Type Of FundingInternal
CategoryINTE
UONY

20052 grants / $3,785

American Thoracic Society Conference, 20 to 25 May 2005$2,000

Funding body: Ian Potter Foundation

Funding bodyIan Potter Foundation
Project TeamDoctor Vanessa Murphy
SchemeTravel Grant
RoleLead
Funding Start2005
Funding Finish2005
GNoG0185081
Type Of FundingDonation - Aust Non Government
Category3AFD
UONY

American Thoracic Society Annual Scientific Conference, 20-25 May 2005$1,785

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamDoctor Vanessa Murphy
SchemeTravel Grant
RoleLead
Funding Start2005
Funding Finish2005
GNoG0185399
Type Of FundingInternal
CategoryINTE
UONY

20041 grants / $269,000

Respiratory Medicine$269,000

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamDoctor Vanessa Murphy, Conjoint Professor Peter Gibson
SchemePort Waratah Coal Service Post-Doctoral Fellowship
RoleLead
Funding Start2004
Funding Finish2004
GNoG0184012
Type Of FundingDonation - Aust Non Government
Category3AFD
UONY

20031 grants / $7,375

Identification of novel sex-specific factors derived from the human fetus.$7,375

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamDoctor Vanessa Murphy
SchemeTravelling Award for Research Training
RoleLead
Funding Start2003
Funding Finish2003
GNoG0182186
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

20001 grants / $52,905

What causes preterm labour in asthmatic pregnancies? The role of placental 11beta-hydroxysteroid dehydrogenase type 2 and corticotropin releasing hormone$52,905

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamDoctor Vanessa Murphy
SchemeDora Lush Postgraduate Research Scholarship
RoleLead
Funding Start2000
Funding Finish2000
GNoG0181963
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY
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Research Supervision

Current Supervision

CommencedResearch Title / Program / Supervisor Type
2014To Determine the Effect of Reduced Asthma Exacerbations During Pregnancy on Markers of Airways Inflammation, Lung Function, and Antiviral Responses in the Offspring at Six Years of Age
General Medicine, Faculty of Health and Medicine
Co-Supervisor

Past Supervision

YearResearch Title / Program / Supervisor Type
2014Asthma and Pregnancy: A Qualitative Descriptive Study of Midwives' Current Knowledge About Asthma in Pregnancy and Their Perceived Role in Antenatal Asthma Management in Australia
Midwifery, Faculty of Health and Medicine
Co-Supervisor
2013Investigation of the Immune Mechanisms in Pregnancy and Asthma Leading to Increased Susceptibility and Disease Severity to Respiratory Virus Infections
General Medicine, Faculty of Health and Medicine
Co-Supervisor
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Dr Vanessa Murphy

Position

NHMRC Career Development Fellow
School of Medicine and Public Health
Faculty of Health and Medicine

Contact Details

Emailvanessa.murphy@newcastle.edu.au
Phone(02) 40420141
Fax(02) 40420046

Office

RoomHMRI West Wing Level 2
BuildingHMRI
LocationOther

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