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Associate Professor Philip Bolton

Associate Professor

School of Biomedical Sciences and Pharmacy (Human Physiology)

Career Summary

Biography

Research Expertise
Dr Bolton has research interests in both the basic and clinical sciences. His laboratory based research focuses on studies concerning how the nervous system processes and integrates sensory information including signals resulting in the perception of pain. His clinical interests and applied research concerns pain, spinal manipulative therapy and the practice of chiropractic. 


Qualifications

  • PhD, University of New South Wales
  • Bachelor of Science (Physiology), University of New England
  • Doctor of Chiropractic, Palmer College of Chiropractic

Keywords

  • Neuroscience
  • Pain
  • Physiology
  • Somatoautonomic
  • Somatosensory

Fields of Research

CodeDescriptionPercentage
110399Clinical Sciences not elsewhere classified30
110999Neurosciences not elsewhere classified35
111699Medical Physiology not elsewhere classified35

Professional Experience

UON Appointment

DatesTitleOrganisation / Department
1/01/2014 - Associate ProfessorUniversity of Newcastle
School of Biomedical Sciences and Pharmacy
Australia

Academic appointment

DatesTitleOrganisation / Department
1/01/2013 - Editorial Board - Journal of Manipulative & Physiological TherapeuticsJournal of Manipulative & Physiological Therapeutics
Australia
1/01/2006 - 1/12/2014Visiting AcademicUniversity of Western Sydney
School of Medicine
Australia

Membership

DatesTitleOrganisation / Department
1/01/2005 - Membership - Australian Pain SocietyAustralian Pain Society
1/01/2005 - Membership - International Society for Autonomic NeuroscienceInternational Society for Autonomic Neuroscience
Australia
1/01/1992 - Membership - Australasian Neuroscience SocietyAustralasian Neuroscience Society
Australia

Invitations

Keynote Speaker

YearTitle / Rationale
2010Convocation (Graduation) Speaker
Organisation: Faculty of Science, Macquarie University, Sydney, NSW
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (4 outputs)

YearCitationAltmetricsLink
1995YATES BJ, GOTO T, BOLTON PS, KERMAN IA, MILLER AD, 'The role of the ventral brainstem in vestibulosympathetic and vestibulorespiratory reflexes', , MARCEL DEKKER 181-191 (1995)
Author URL
1994Bolton PS, Uchino Y, Sasaki M, Imagawa M, Endo K, Ikegami H, et al., 'The utriculo-neck reflex arc of the decerebrate cat', Vestibular and Neural Front, Elsevier Science, . 445-448 (1994)
1992Bolton PS, Wilson VJ, Goto T, Schor RH, Yamagata Y, Yates BJ, 'Spatial Transformation in the Vertical Vestibulocollic Reflex', Sensing and Controlling Motion: Vestibular and Sensorimotor Function, Wiley, Chichester, UK. 500-506 (1992)
DOI10.1111/j.1749-6632.1992.tb25231.x
CitationsWeb of Science - 3
1992Bolton PS, Tracey DJ, 'Somatosensory pathways from the neck', The Head -Neck Sensory Motor System, Oxford University Press, New York 171-174 (1992)
Show 1 more chapter

Journal article (66 outputs)

YearCitationAltmetricsLink
2015Griffin C, Choong WY, Teh W, Buxton AJ, Bolton PS, 'Head and cervical spine posture in behaving rats: Implications for modeling human conditions involving the head and cervical spine', Anatomical Record, 298 455-462 (2015)

The aim of this study was to define the temporal and spatial (postural) characteristics of the head and cervical vertebral column (spine) of behaving rats in order to better understand their suitability as a model to study human conditions involving the head and neck. Time spent in each of four behavioral postures was determined from video tape recordings of rats (n=10) in the absence and presence of an intruder rat. Plain film radiographic examination of a subset of these rats (n=5) in each of these postures allowed measurement of head and cervical vertebral column positions adopted by the rats. When single they were quadruped or crouched most (~80%) of the time and bipedal either supported or free standing for only ~10% of the time. The introduction of an intruder significantly (P<0.0001) reduced the proportion of time rats spent quadruped (median, from 71% to 47%) and bipedal free standing (median, from 2.9% to 0.4%). The cervical spine was orientated (median, 25-75 percentile) near vertical (18.8°, 4.2°-30.9°) when quadruped, crouched (15.4°, 7.6°-69.3°) and bipedal supported (10.5°, 4.8°-22.6°) but tended to be less vertical oriented when bipedal free standing (25.9°, 7.7°-39.3°). The range of head positions relative to the cervical spine was largest when crouched (73.4°) and smallest when erect free standing (17.7°). This study indicates that, like humans, rats have near vertical orientated cervical vertebral columns but, in contrast to humans, they displace their head in space by movements at both the cervico-thoracic junction and the cranio-cervical regions. Anat Rec, 298:455-462, 2015.

DOI10.1002/ar.23049
Co-authorsTony Buxton
2014Bolton PS, Hammam E, Macefield VG, 'Neck proprioceptors contribute to the modulation of muscle sympathetic nerve activity to the lower limbs of humans', EXPERIMENTAL BRAIN RESEARCH, 232 2263-2271 (2014) [C1]
DOI10.1007/s00221-014-3917-xAuthor URL
CitationsScopus - 1Web of Science - 1
2014Hammam E, Bolton PS, Kwok K, Macefield VG, 'Vestibular modulation of muscle sympathetic nerve activity during sinusoidal linear acceleration in supine humans', Frontiers in Neuroscience, 8 1-7 (2014) [C1]
DOI10.3389/fnins.2014.00316
2014Harris BM, Hughes DI, Bolton PS, Tadros MA, Callister RJ, Graham BA, 'Contrasting alterations to synaptic and intrinsic properties in upper-cervical superficial dorsal horn neurons following acute neck muscle inflammation', MOLECULAR PAIN, 10 (2014) [C1]
DOI10.1186/1744-8069-10-25Author URL
CitationsScopus - 2Web of Science - 2
Co-authorsRobert Callister, Brett Graham
2014Yates BJ, Bolton PS, Macefield VG, 'Vestibulo-Sympathetic Responses', COMPREHENSIVE PHYSIOLOGY, 4 851-887 (2014) [C1]
DOI10.1002/cphy.c130041Author URL
CitationsScopus - 2Web of Science - 3
2014Yates BJ, Bolton PS, Macefield VG, 'Vestibulo-sympathetic responses.', Compr Physiol, 4 851-887 (2014) [D1]
DOI10.1002/cphy.c130041Author URL
CitationsScopus - 2Web of Science - 3
2013Bent LR, Sander M, Bolton PS, Macefield VG, 'The vestibular system does not modulate fusimotor drive to muscle spindles in contracting leg muscles of seated subjects', EXPERIMENTAL BRAIN RESEARCH, 227 175-183 (2013) [C1]
DOI10.1007/s00221-013-3497-1Author URL
CitationsScopus - 2Web of Science - 2
2013Parkinson L, Sibbritt D, Bolton P, van Rotterdam J, Villadsen I, 'Well-being outcomes of chiropractic intervention for lower back pain: a systematic review', CLINICAL RHEUMATOLOGY, 32 167-180 (2013) [C1]
DOI10.1007/s10067-012-2116-zAuthor URL
CitationsScopus - 1
Co-authorsL Parkinson
2013Bigland MJ, Budgell BS, Bolton PS, 'The influence of cervical spinal cord compression and vertebral displacement on somatosympathetic reflexes in the rat', Spine Journal, (2013)

Background context: One theory within chiropractics proposes that vertebral subluxation in the upper cervical region induces spinal cord compression sufficient to alter spinal cord efferent output. We report on the feasibility of three different experimental approaches to test this theory. Methods: A high threshold electrical-evoked somatosympathetic reflex was recorded in adrenal or renal nerves of 10 anaesthetized adult male rats before and after (1) graded pressure was applied directly to the C1/C2 spinal cord segment in eight rats by the use of either direct compression or inflation of an extradural balloon and (2) displacement, less than a dislocation applied posterior to anterior, to the C2 vertebra in two rats. The latency and amplitude of the pre- and postintervention reflex responses were compared. Results: The reflex amplitude was not significantly changed by pressure (26 mmHg) from an extra-dural balloon or direct compression of the dura mater onto the dorsal spinal cord. Additional pressure, at least sufficient to occlude the dorsal vessels, induced a significant reduction in the amplitude of the reflex, and this reduction persisted for 20 minutes after removal of the pressure (Dunn's method for all pairwise multiple comparison Q stat=3.437; critical value for k=6 with a=0.05 is 2.936). Maximal vertebral (C2) displacement (4 mm), without dislocation did not induce significant changes compared with the control period. Conclusions: Although this feasibility study suggests it is unlikely that upper cervical vertebral subluxation, displacement less than a dislocation, compromises the sympathetic outflow in the adrenal or renal nerves, further vertebral displacement studies are necessary to formally test this. © 2013 Elsevier Inc. All rights reserved.

DOI10.1016/j.spinee.2013.08.013
2013Smith J, Bolton PS, 'What Are the Clinical Criteria Justifying Spinal Manipulative Therapy for Neck Pain? A Systematic Review of Randomized Controlled Trials', PAIN MEDICINE, 14 460-468 (2013) [C1]
DOI10.1111/pme.12041Author URL
CitationsScopus - 3Web of Science - 2
2012Bolton PS, Budgell B, 'Visceral responses to spinal manipulation', Journal of Electromyography and Kinesiology, 22 777-784 (2012) [C1]
CitationsScopus - 5Web of Science - 2
2012Pickar JG, Bolton PS, 'Spinal manipulative therapy and somatosensory activation', Journal of Electromyography and Kinesiology, 22 785-794 (2012) [C1]
CitationsScopus - 19Web of Science - 11
2010Budgell BS, Bolton PS, 'Cerebrospinal fluid pressure response to upper cervical vertebral motion and displacement in the anesthetized rat', Journal of manipulative and physiological therapeutics, 33 355-361 (2010) [C1]
DOI10.1016/j.jmpt.2010.05.007
CitationsScopus - 1Web of Science - 1
2010Graham BA, Clausen PD, Bolton PS, 'A descriptive study of the force and displacement profiles of the toggle-recoil spinal manipulative procedure (adjustment) as performed by chiropractors', Manual Therapy, 15 74-79 (2010) [C1]
DOI10.1016/j.math.2009.07.003
CitationsScopus - 10Web of Science - 7
Co-authorsBrett Graham, Philip Clausen
2009Burton AR, Birznieks I, Bolton PS, Henderson LA, Macefield VG, 'Effects of deep and superficial experimentally induced acute pain on muscle sympathetic nerve activity in human subjects', Journal of Physiology, 587 183-193 (2009) [C1]
DOI10.1113/jphysiol.2008.162230
CitationsScopus - 31Web of Science - 28
2009Thomas L, Rivett DA, Bolton PS, 'Validity of the Doppler velocimeter in examination of vertebral artery blood flow and its use in pre-manipulative screening of the neck', Manual Therapy, 14 544-549 (2009) [C1]
DOI10.1016/j.math.2008.08.007
CitationsScopus - 7Web of Science - 3
Co-authorsDarren Rivett, Lucy Thomas
2009Thomas L, Rivett DA, Bolton PS, 'Comments in response to letter to the editor', Manual Therapy, 14 E7-E8 (2009) [C3]
DOI10.1016/j.math.2009.04.005
Co-authorsLucy Thomas, Darren Rivett
2009Thomas L, Rivett DA, Bolton PS, 'Comments in response to letter to the editor by Karl et al. Manual Therapy 2009;14(6):e17', Manual Therapy, 14 E18 (2009) [C3]
DOI10.1016/j.math.2009.07.006
Co-authorsDarren Rivett, Lucy Thomas
2008Thomas L, Rivett DA, Bolton PS, 'Pre-manipulative testing and the use of the velocimeter', Manual Therapy, 13 29-36 (2008) [C1]
DOI10.1016/j.math.2006.11.003
CitationsScopus - 4Web of Science - 4
Co-authorsLucy Thomas, Darren Rivett
2008Thomas L, Rivett DA, Bolton PS, 'Comments in response to letters to editor regarding article: Thomas LC, et al. Premanipulative testing and the velocimeter. Manual Therapy (2007)', Manual Therapy, 13 E5-E6 (2008) [C3]
DOI10.1016/j.math.2007.09.010
CitationsScopus - 1
Co-authorsLucy Thomas, Darren Rivett
2008Bolton PS, Rivett DA, Thomas L, 'Comments in response to letters to editor regarding article', Manual Therapy, 13 .-. (2008)
2007Flynn JR, Bolton PS, 'Measurement of the vertebral canal dimensions of the neck of the rat with a comparison to the human', Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 290 893-899 (2007) [C1]
DOI10.1002/ar.20523
CitationsScopus - 10Web of Science - 9
2007Bent LR, Bolton PS, Macefield VG, 'Vestibular inputs do not influence the fusimotor system in relaxed muscles of the human leg', Experimental Brain Research, 180 97-103 (2007) [C1]
DOI10.1007/s00221-006-0836-5
CitationsScopus - 4Web of Science - 4
2007Budgell BS, Bolton PS, 'Cerebrospinal Fluid Pressure in the Anesthetized Rat', Journal of Manipulative and Physiological Therapeutics, 30 351-356 (2007) [C1]
DOI10.1016/j.jmpt.2007.04.002
CitationsScopus - 4Web of Science - 5
2006Bolton PS, Budgell B, Kimpton A, 'Influence of innocuous cervical vertebral movement on the efferent innervation of the adrenal gland in the rat', Autonomic Neuroscience-Basic & Clinical, 124 103-111 (2006) [C1]
DOI10.1016/j.autneu.2005.12.004
CitationsScopus - 6Web of Science - 4
2006Bent LR, Bolton PS, Macefield VG, 'Modulation of muscle sympathetic bursts by sinusoidal galvanic vestibular stimulation in human subjects', Experimental Brain Research, 174 701-711 (2006) [C1]
DOI10.1007/s00221-006-0515-6
CitationsScopus - 32Web of Science - 29
2005Rivett DA, Thomas L, Bolton PS, 'Pre-manipulative testing: where do we go from here?', New Zealand Journal of Physiotherapy, 33 78-84 (2005) [C1]
Co-authorsLucy Thomas, Darren Rivett
2005Bolton PS, Budgell BS, 'Spinal manipulation and spinal mobilization influence different axial sensory beds', Medical Hypotheses, 66 258-262 (2005) [C1]
DOI10.1016/j.mehy.2005.08.054
CitationsScopus - 20Web of Science - 17
2004Bolton PS, Wardman DL, Macefield VG, 'Absence of short-term vestibular modulation of muscle sympathetic outflow, assessed by brief galvanic vestibular stimulation in awake human subjects', Experimental Brain Research, 154 39-43 (2004) [C1]
DOI10.1007/s00221-003-1631-1
CitationsScopus - 14Web of Science - 12
2002Bolton PS, 'Minimum standards for cervical manipulation are in the public interest. Comment', AUSTRALIAN JOURNAL OF PHYSIOTHERAPY, 48 313-313 (2002)
Author URL
2001Bolton PS, 'Neck Mechanoreceptor Influence on Lower Limb Posture Cervical Isolation Tests', Activator Vision, 16 No 1 6-10 (2001) [C3]
2000Bolton PS, 'Reflex effects of vertebral subluxations: the peripheral nervous system. An update', Journal of Manipulative and Physiological Therapeutics, 23, No 2 101-103 (2000) [C1]
CitationsScopus - 12Web of Science - 7
2000Bolton PS, Ray C, 'Neck afferent involvement in cardiovascular control during movement', Brain Research Bulletin, 53, No 1 45-49 (2000) [C1]
CitationsScopus - 10Web of Science - 10
1998Bolton PS, Kerman I, Woodring S, Yates B, 'Influences of neck afferents on sympathetic and respiratory nerve activity', Brain Research Bulletin, 47(5) 413-419 (1998) [C1]
CitationsScopus - 22Web of Science - 18
1998Bolton PS, 'The Somatosensory System of the Neck and Its Effects on the Central Nervous System', Journal of Manipulative and Physiological Therapeutics, 21(8) 553-563 (1998) [C1]
CitationsScopus - 27Web of Science - 17
1998Bolton PS, Holland CT, 'An in vivo method for studying afferent fibre activity from cervical paravertebral tissue during vertebral motion in anaesthetised cats', Journal of Neuroscience Methods, 85 211-218 (1998) [C1]
CitationsWeb of Science - 13
1997Brophy GM, Rossiter CD, Bolton PS, Yates BJ, 'Vestibular influences on cat lumbar paravertebral muscles', NEUROSCIENCE LETTERS, 223 189-192 (1997)
DOI10.1016/S0304-3940(97)13432-2Author URL
CitationsScopus - 4Web of Science - 3
1996Bolton PS, 'Acute Torticollis and Palmer Upper cervical specific technique: A report of three cases', Chiropractic Journal of Australia, 89-93 (1996) [C3]
1994WALMSLEY B, BOLTON PS, 'AN IN-VIVO PHARMACOLOGICAL STUDY OF SINGLE GROUP-I A FIBER CONTACTS WITH MOTONEURONS IN THE CAT SPINAL-CORD', JOURNAL OF PHYSIOLOGY-LONDON, 481 731-741 (1994)
Author URL
CitationsScopus - 20Web of Science - 21
1993YATES BJ, GOTO T, BOLTON PS, 'RESPONSES OF NEURONS IN THE ROSTRAL VENTROLATERAL MEDULLA OF THE CAT TO NATURAL VESTIBULAR STIMULATION', BRAIN RESEARCH, 601 255-264 (1993)
DOI10.1016/0006-8993(93)91718-8Author URL
CitationsScopus - 57Web of Science - 66
1993BOLTON PS, GOTO T, WILSON VJ, 'HORIZONTAL CANAL INPUT TO UPPER CERVICAL COMMISSURAL NEURONS', EXPERIMENTAL BRAIN RESEARCH, 92 549-552 (1993)
Author URL
CitationsScopus - 7Web of Science - 12
1993YATES BJ, GOTO T, KERMAN I, BOLTON PS, 'RESPONSES OF CAUDAL MEDULLARY RAPHE NEURONS TO NATURAL VESTIBULAR STIMULATION', JOURNAL OF NEUROPHYSIOLOGY, 70 938-946 (1993)
Author URL
CitationsScopus - 17Web of Science - 24
1993Ivancic J, Bryce D, Bolton PS, 'Use of provocational tests by clinicians to predict vulnerability of patients to vertebrobasilar insufficiency', Chiropractic Journal of Australia, 23 59-63 (1993) [C1]
1993Bolton PS, Goto B, Yates BJ, 'Analysis of vestibular input to neurones in the rostral ventrolateral medulla of the cat by natural stimulation', Japanese Journal Physiology, 43 274 (1993)
1993Bolton PS, Goto T, Kerman IA, Yates BJ, 'Analysis of vestibular input to the caudal medullary raphespinal neurones by natural stimulation in the cat', Neuroscience Research, 18 168-. (1993)
1992Bolton PS, Tracey DJ, 'Neurons in the dorsal column nuclei of the rat respond to stimulation of neck mechanoreceptors and project to the thalamus', Brain Research, 595 175-179 (1992)

Electrophysiological recordings were made from neurons in the dorsal column nuclei which were activated by stimulation of muscle and cutaneous receptors in the neck of the rat. 222 units were studied, 158 (71%) of which responded to activation of cutaneous mechanoreceptors while 64 (29%) were activated by muscle receptors. The response patterns of 12 neurons with input from receptors in neck muscles were tested more fully. Their response patterns strongly suggested that 6 were activated by muscle spindle afferents while the other 6 were activated by Golgi tendon organ afferents. 18 (8%) of the neck-responsive neurons in the medulla were shown to project rostrally to the thalamus. © 1992.

DOI10.1016/0006-8993(92)91472-Q
CitationsScopus - 1
1992YATES BJ, GOTO T, BOLTON PS, 'RESPONSES OF NEURONS IN THE CAUDAL MEDULLARY RAPHE NUCLEI OF THE CAT TO STIMULATION OF THE VESTIBULAR NERVE', EXPERIMENTAL BRAIN RESEARCH, 89 323-332 (1992)
Author URL
CitationsScopus - 19Web of Science - 28
1992Bolton PS, Tracey DJ, 'The medullary relay from neck receptors to somatosensory thalamus in the rat: A neuroanatomical study', Experimental Brain Research, 88 473-484 (1992)

Experiments were performed on rats to determine the location of thalamic projecting neurones in the medulla which receive direct contacts from neck primary afferents. The medullary terminations of primary afferents from the cervical region were identified by silver staining their degenerating terminals, diffusely filling their axons with horseradish peroxidase (HRP), or reacting for transganglionically transported HRP applied to muscle or cutaneous nerves. Neurones projecting to the ventrobasal thalamus were identified in the same experimental animals by using retrograde transport of HRP or Fluoro-Gold. En passant swellings or terminals of neck primary afferents were found in the vicinity of neurones projecting to the thalamus in the dorsolateral part of the rostral cuneate nucleus, the ventral aspect of the external cuneate nucleus, and the border zone between the two. Terminals of neck afferents and retrogradely labelled cells also coincided in nucleus x. Putative synaptic contacts were found in the region between the dorsolateral part of the rostral cuneate nucleus and ventromedial external cuneate nucleus. Cutaneous afferents from the neck were associated with thalamic projecting cells located along the dorsolateral border of the rostral cuneate nucleus, and afferents from neck muscles were associated with thalamic projecting cells in the caudal third of the external cuneate nucleus and in nucleus x.

CitationsScopus - 7
1992Bolton PS, Tracey DJ, 'Spinothalamic and propriospinal neurones in the upper cervical cord of the rat: Terminations of primary afferent fibres on soma and primary dendrites', Experimental Brain Research, 92 59-68 (1992)

Experiments were performed on rats to determine whether primary afferents from the upper cervical region terminate directly on spinothalamic and propriospinal neurones. The central terminations of primary afferents from the upper cervical region were identified by diffusely filling their axons with horseradish peroxidase. Spinothalamic neurones or propriospinal neurones were identified in the same experimental animals by using retrograde transport of wheat germ agglutinin conjugated to horseradish peroxidase. Approximately 3-11% of spinothalamic cells in laminae 4-6 of spinal segments C2-4 received apparent synaptic contacts from primary afferents on the soma or primary dendrites. Approximately 18-36% of propriospinal neurones with axons descending to lower thoracic or lumbar levels received apparent synaptic contacts on the soma or primary dendrites. These data provide anatomical evidence that spinothalamic and long propriospinal neurones in the upper cervical cord are excited directly by primary afferents. The data also help to clarify the neural circuitry underlying somatic sensation and reflex movements evoked by neck receptors.

CitationsScopus - 8
1992BOLTON PS, GOTO T, SCHOR RH, WILSON VJ, YAMAGATA Y, YATES BJ, 'RESPONSE OF PONTOMEDULLARY RETICULOSPINAL NEURONS TO VESTIBULAR STIMULI IN VERTICAL PLANES - ROLE IN VERTICAL VESTIBULOSPINAL REFLEXES OF THE DECEREBRATE CAT', JOURNAL OF NEUROPHYSIOLOGY, 67 639-647 (1992)
Author URL
CitationsScopus - 50Web of Science - 62
1992BOLTON PS, ENDO K, GOTO T, IMAGAWA M, SASAKI M, UCHINO Y, WILSON VJ, 'CONNECTIONS BETWEEN UTRICULAR NERVE AND DORSAL NECK MOTONEURONS OF THE DECEREBRATE CAT', JOURNAL OF NEUROPHYSIOLOGY, 67 1695-1697 (1992)
Author URL
CitationsScopus - 36Web of Science - 40
1992WILSON VJ, BOLTON PS, GOTO T, SCHOR RH, YAMAGATA Y, YATES BJ, 'SPATIAL TRANSFORMATION IN THE VERTICAL VESTIBULOCOLLIC REFLEX', ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 656 500-506 (1992)
DOI10.1111/j.1749-6632.1992.tb25231.xAuthor URL
CitationsScopus - 1Web of Science - 3
1992BOLTON PS, 'ASSESSMENT OF CERVICAL VERTIGO', JOURNAL OF MANIPULATIVE AND PHYSIOLOGICAL THERAPEUTICS, 15 267-268 (1992)
Author URL
1991YATES BJ, YAMAGATA Y, BOLTON PS, 'THE VENTROLATERAL MEDULLA OF THE CAT MEDIATES VESTIBULOSYMPATHETIC REFLEXES', BRAIN RESEARCH, 552 265-272 (1991)
DOI10.1016/0006-8993(91)90091-9Author URL
CitationsScopus - 69Web of Science - 78
1991BOLTON PS, 'ASSESSMENT OF CERVICOGENIC VERTIGO', JOURNAL OF MANIPULATIVE AND PHYSIOLOGICAL THERAPEUTICS, 14 487-487 (1991)
Author URL
CitationsWeb of Science - 1
1991BOLTON PS, GOTO T, WILSON VJ, 'COMMISSURAL NEURONS IN THE CAT UPPER CERVICAL SPINAL-CORD', NEUROREPORT, 2 743-746 (1991)
DOI10.1097/00001756-199112000-00003Author URL
CitationsScopus - 11Web of Science - 21
1991Bolton PS, 'Options for scientifically valid research', Chiropractic Journal of Australia, 12 20-21 (1991)
1989Bolton PS, Stick PE, Lord RS, 'Failure of clinical tests to predict cerebral ischemia before neck manipulation', Journal Manipulative Physiology Therapy, 12 304-307 (1989)
1988Bolton PS, Ware AE, 'Degenerative joint disease in the cervical spine of chiropractic patients', Journal of Australian Chiropractic Association, 18 51-54 (1988)
1988Bolton PS, Posters P, 'What are they', Journal of Australian Chiropractic Association, 18 29-30 (1988)
1988Bolton PS, 'Peer review of manuscripts: Why bother?', Journal of Australian Chiropractic Association, 18 140-141 (1988)
1988Bolton PS, 'Treatment of lumbar motor unit instability with a custom orthosis: clinical procedure', Journal of Manipulative and Physiological Therapeutics, 11 443 (1988)
1986Bolton PS, Minter, 'WR Sacral base angle and lumbosacral zygapophyseal joint facet orientation', Journal of Australian Chiropractic Association, 16 103-106 (1986)
1986Bolton PS, 'A Radiographic spirit level', Journal of Australian Chiropractic Association, 14 48-50 (1986)
1985Bolton PS, Youcham TR, 'Low back pain or camptcormia', Journal of Australian Chiropractic Association, 18 51-53 (1985)
1985Bolton PS, 'Torticollis: a review of etiology, pathology, diagnosis and treatment', Journal of Australian Chiropractic Association, 8 29-32 (1985)
Show 63 more journal articles

Conference (34 outputs)

YearCitationAltmetricsLink
2013Bolton PS, Hammam E, Macefield V, 'Do proprioceptive afferents from the neck contribute to the vestibular modulation of muscle sympathetic nerve activity supplying the lower limbs of humans?', Australian Neuroscience Society (2013) [E3]
2010Bolton PS, Harris BM, Walsh MA, 'Electrophysiological properties of superficial dorsal horn neurons in upper-cervical spinal segments in neonate and adult mice', Australian Neuroscience Society (2010) [E3]
2010Bolton PS, Budgell BS, 'Somato-adrenal reflex and upper cervical spinal cord compression-a pilot study', Australian Neuroscience Society (2010) [E3]
2010Bolton PS, Eddy K, Jobling P, 'Characteristics of neurons with input from deep neck structures', Australian Neuroscience Society (2010) [E3]
2010Harris BM, Graham BA, Bolton PS, Brichta AM, Callister RJ, 'Influence of acute neck muscle inflammation on the excitability of superficial dorsal horn neurons', 13th World Congress on Pain: Abstracts, Montreal, QC (2010) [E3]
Co-authorsAlan Brichta, Robert Callister, Brett Graham
2008Thomas L, Bolton P, Rivett DA, 'Validity of the Doppler velocimeter for pre-manipulative screening of vertebral artery blood flow.', 9th International Conference of the International Federation of Orthopaedic Manipulative Therapists (IFOMT) Abstracts CD., Rotterdam, The Netherlands (2008)
Co-authorsLucy Thomas, Darren Rivett
2005Bolton PS, Holland CT, 'Response characteristics of deep paravertebral muscle spindle afferents to vestibular movements in the neck of the cat', Australian Neuroscience Society (2005)
2005Bolton PS, Brent LR, Macefield VG, 'Vestibular influences on spindles in relaxed human muscles', Proc Aust. Neuroscience Soc. (2005)
2005Bolton PS, Thomas LC, Rivett DA, 'Validity and reliability of the doppler velocimeter for pre-manipulative screening of vertebral artery blood flow', Proceedings 14th Biennial Conference Musculoskeletal Physiotherapy Australia. (2005) [E3]
Co-authorsDarren Rivett, Lucy Thomas
2005Bolton PS, Bent LR, Sander M, Macefield VG, 'Can vestibular input modulate spindle activity in relaxed and active human lower leg muscles?', Society for Neuroscience (2005)
2004Bolton PS, Budgell B, Kimpton A-J, 'Influence of Innocuous Neck Movements on the Sympathetic Outflow to the Adrenal Gland in the Rat', Proceeding of the Australian Neuroscience Society, Melbourne (2004) [E3]
2004Bolton PS, Budgell B, Kimpton A, 'Influence of innocuous neck movements on the sympathetic outflow to the adrenal gland in the rat', Proceedings Australian Neuroscience Society (2004)
2004Bent LR, Bolton PS, Macefield VG, 'Continuous Galvanic Vestibular Stimulation Modulates Muscles Sympathetic Nerve Activity in the Lower Limbs of Awake Humans During Standing', Proceedings of the Australian Neuroscience Society, Melbourne (2004) [E3]
2003Thomas L, Rivett DA, Bolton PS, 'Changes in Vertebral Artery Blood Flow During Neck Rotation', Musculoskeletal Physiotherapy Australia 13th Biennial Conference, Sydney, Australia (2003) [E3]
Co-authorsDarren Rivett, Lucy Thomas
2003Bolton PS, Spaak J, Gandevia SC, Macefield VG, 'Induced muscle pain increases muscle sympathetic nerve activity in human subjects', Proceedings Australian Neuroscience Society (2003)
2003Bolton PS, Wardman DL, Macefield VG, 'Continuous Glavanic Vestibular Stimulation (GVS) Does Not Increase Muscle Sympathetic Nerve Activity in Awake Human Subjects', Proceedings of the Australian Neuroscience Society, Adelaide Convention Centre, Australia (2003) [E3]
2002Bolton PS, Wardman D, Macefield V, 'Effects of Galvanic Stimulation on Sympathetic Outflow in Awake Human Subjects', Proceedings of the Australian Neuroscience Society, Sydney, NSW, Australia (2002) [C3]
1998Bolton PS, Kerman IA, Yates BJ, 'Integration of vestibular and neck influences on cardiovascular and respiratory control', JARO: Journal of the Association for Research in Otolaryngology (1998)
1997Bolton PS, Kermin AI, Woodring SF, Bates BJ, 'Sympathetic and respiratory nerve responses to neck afferent stimulation', Society Neuroscience (1997)
1996Bolton PS, Goto T, Kermin IA, Bates BJ, 'Descending pathways responsible for vestibulo-sympathetic responses', Journal Vestibular Research (1996)
1996Bolton PS, Holland CT, 'Afferent signalling of vertebral displacement in the neck of the cat', Soc. Neurosci. Abstr (1996)
1995Bolton PS, Hayek R, 'Spinal cord projections of primary afferents from C2/C3 articular and periarticular tissues of the neck in the rat', Proc. Aust. Neurosci. Soc (1995)
1993Bolton PS, Wilson VJ, Goto T, Bankoul S, 'Upper cervical interneurons and vestibulocollic reflex.', International Union of Physiol. Soc. (1993)
1993Bolton PS, 'The effects of NBQX on single Group Ia fibre EPSPs evoked in cat spinal motoneurones', Proc. Australian Neuroscience Society (1993)
1993Bolton PS, Goto T, Yates BJ, 'Vestibular inputs to raphaespinal neurones in the cat: possible contributions to motor and autonomic control', Proc. Australian Neuroscience Society (1993)
1993Bolton PS, Goto T, Wilson VJ, 'Upper cervical commissural neurons and the vestibulocollic reflex', Proc. Australian Neuroscience Society (1993)
1992Bolton PS, Endo K, Goto T, Imagawa M, Sasaki M, Uchino Y, Wilson VJ, 'Utricular input to dorsal neck motoneurons of the cat', Proc. 69th Ann. Meeting Physiol. Soc. of Japan. (1992)
1992Bolton PS, Goto T, Yates BJ, 'Vestibular inputs to raphespinal neurons in the cat: Implications for autonomic and motor control', Soc. Neurosci. (1992)
1992Bolton PS, Yates T, Goto BJ, 'Responses of neurons in the subretrofacial rostral ventrolateral medulla (RVLM) of the cat to natural vestibular stimulation', Society Neuroscience (1992)
1991Bolton PS, Yates BJ, Yamagata Y, 'The subretrofacial nucleus (SRFN) of the cat participates in the vestibulosymapthetic reflexes', Proc. International Brain Research Organisation, Third World Congress of Neuroscience (1991)
1991Bolton PS, Goto T, Schor R, Wilson V, Yamagata Y, Yates B, 'Reticulospinal neurons and vertical vestibulospinal reflexes', Society Neuroscience (1991)
1990Bolton PS, Tracey DJ, 'Terminations of cervical primary afferents on cuneothalamic and cuneocerebellar neurones.', Proc. Aus. Neurosci. Society (1990)
1989Bolton PS, Tracey DJ, 'The medullary relay for the projections from the neck afferents to somatosensory thalamus in the rat. The head-neck sensory-motor system', International Brain Research Organisation (1989)
1989Bolton PS, Tracey DJ, 'Terminations of cervical primary afferents on spinothalamic, propriospinal and spinocerebellar neurons', Society Neuroscience (1989)
Show 31 more conferences
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Grants and Funding

Summary

Number of grants30
Total funding$1,018,372

Click on a grant title below to expand the full details for that specific grant.


20152 grants / $12,000

2015 International Visitor from Northwestern University, USA$10,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor Philip Bolton, Associate Professor James Elliott
SchemeInternational Research Visiting Fellowship
RoleLead
Funding Start2015
Funding Finish2015
GNoG1401278
Type Of FundingInternal
CategoryINTE
UONY

International Society for Autonomic Neuroscience, Stresa Italy, 26-29 September 2015$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding bodyUniversity of Newcastle - Faculty of Health and Medicine
Project TeamAssociate Professor Philip Bolton
SchemeTravel Grant
RoleLead
Funding Start2015
Funding Finish2015
GNoG1500415
Type Of FundingInternal
CategoryINTE
UONY

20141 grants / $20,000

Pilot study to discover neural and kinematic biomarkers in chronic non-specific neck pain that provide biological evidence for patient outcomes following chiropractic care$20,000

Funding body: Australian Spinal Research Foundation

Funding bodyAustralian Spinal Research Foundation
Project TeamAssociate Professor Suzanne Snodgrass, Professor Darren Rivett, Associate Professor Philip Bolton, Associate Professor Peter Stanwell, Doctor Patrick McElduff
SchemeResearch Grant
RoleInvestigator
Funding Start2014
Funding Finish2014
GNoG1300738
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

20111 grants / $9,250

Chiropractic care in Australia: exploring quality of life, health and economic impacts of chiropractic intervention for people with back pain$9,250

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamConjoint Professor David Sibbritt, Conjoint Associate Professor Lynne Parkinson, Associate Professor Philip Bolton
SchemeLinkage Pilot Research Grant
RoleInvestigator
Funding Start2011
Funding Finish2011
GNoG1100875
Type Of FundingInternal
CategoryINTE
UONY

20103 grants / $84,065

ABI 7500 Real Time PCR System $34,000

Funding body: NHMRC (National Health & Medical Research Council)

Do chiropractic vertebral adjustments modulate sympathetic nerve activity in humans$28,350

Funding body: Australian Spinal Research Foundation

Funding bodyAustralian Spinal Research Foundation
Project TeamAssociate Professor Philip Bolton, Professor Robin Callister
SchemeResearch Grant
RoleLead
Funding Start2010
Funding Finish2010
GNoG0190386
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Do chiropractic spinal adjustments modulate brain derived neurotrophic factor levels in the brain - a study in the rodent$21,715

Funding body: Australian Spinal Research Foundation

Funding bodyAustralian Spinal Research Foundation
Project TeamAssociate Professor Philip Bolton, Associate Professor Paul Tooney
SchemeResearch Grant
RoleLead
Funding Start2010
Funding Finish2010
GNoG0190387
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

20093 grants / $496,144

Spinal mechanisms underlying neck pain$451,500

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamProfessor Robert Callister, Associate Professor Philip Bolton, Professor Alan Brichta
SchemeProject Grant
RoleInvestigator
Funding Start2009
Funding Finish2009
GNoG0188840
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Neurometer CPT/C$28,435

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamAssociate Professor Philip Bolton, Professor Robert Callister, Professor Alan Brichta, Professor Robin Callister, Doctor Brett Graham, Doctor Phil Jobling
SchemeEquipment Grant
RoleLead
Funding Start2009
Funding Finish2009
GNoG0189845
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

Leica VT1200S - Fully automated vibrating blade microtome$16,209

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamProfessor Robert Callister, Professor Alan Brichta, Conjoint Professor Keith Jones, Professor Jon Hirst, Doctor Brett Graham, Associate Professor Philip Bolton, Doctor Phil Jobling, Associate Professor Paul Tooney, Doctor Angela McPherson, Doctor Rebecca Lim, Doctor Ramatis De Oliveira, Mr Matthew Walsh
SchemeEquipment Grant
RoleInvestigator
Funding Start2009
Funding Finish2009
GNoG0189842
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

20084 grants / $71,546

A study of vertebral subluxation and the effects of spinal cord compression on somatic evoked autonomic reflexes$26,752

Funding body: Australian Spinal Research Foundation

Funding bodyAustralian Spinal Research Foundation
Project TeamAssociate Professor Philip Bolton, Mr Brian Budgell
SchemeResearch Grant
RoleLead
Funding Start2008
Funding Finish2008
GNoG0187754
Type Of FundingGrant - Aust Non Government
Category3AFG
UONY

Recovery of the balance system following injury$24,069

Funding body: Hunter Medical Research Institute

Funding bodyHunter Medical Research Institute
Project TeamProfessor Alan Brichta, Professor Robert Callister, Associate Professor Philip Bolton, Doctor Phil Jobling, Doctor Rebecca Lim
SchemeProject Grant
RoleInvestigator
Funding Start2008
Funding Finish2008
GNoG0188471
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

Leica VT2100S Vibrating Microtome$20,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamProfessor Alan Brichta, Professor Robert Callister, Professor Dirk Van Helden, Associate Professor Philip Bolton, Doctor Rebecca Lim, Doctor Brett Graham, Dr Marcus Howlett, Doctor Angela McPherson, Doctor Mohammad Imtiaz, Doctor Ramatis De Oliveira, Mr Wayne Anderson, Mr Matthew Walsh
SchemeEquipment Grant
RoleInvestigator
Funding Start2008
Funding Finish2008
GNoG0188540
Type Of FundingOther Public Sector - Commonwealth
Category2OPC
UONY

Australian Neuroscience Society Annual Scientific Meeting, Hotel Grand Chancellor Hobart, 27/1/2008 - 30/1/2008$725

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor Philip Bolton
SchemeTravel Grant
RoleLead
Funding Start2008
Funding Finish2008
GNoG0188491
Type Of FundingInternal
CategoryINTE
UONY

20071 grants / $7,678

Developing a rodent model to study neck pain$7,678

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamProfessor Robert Callister, Associate Professor Philip Bolton, Professor Alan Brichta, Doctor Brett Graham
SchemePilot Grant
RoleInvestigator
Funding Start2007
Funding Finish2007
GNoG0187879
Type Of FundingInternal
CategoryINTE
UONY

20052 grants / $28,124

Cerebrospinal fluid pressure changes during upper cervical displaclement and chiropractic adjustment$27,517

Funding body: Australian Spinal Research Foundation

Funding bodyAustralian Spinal Research Foundation
Project TeamAssociate Professor Philip Bolton, Mr Brian Budgell
SchemeResearch Grant
RoleLead
Funding Start2005
Funding Finish2005
GNoG0185571
Type Of FundingDonation - Aust Non Government
Category3AFD
UONY

25th Annual Australian Neuroscience Society Meeting, 30 Jan - 2 Feb 2005$607

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor Philip Bolton
SchemeTravel Grant
RoleLead
Funding Start2005
Funding Finish2005
GNoG0185016
Type Of FundingInternal
CategoryINTE
UONY

20031 grants / $723

Australian Neuroscience Society, Adelaide, SA 28-31 January 2003$723

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor Philip Bolton
SchemeTravel Grant
RoleLead
Funding Start2003
Funding Finish2003
GNoG0182644
Type Of FundingInternal
CategoryINTE
UONY

20021 grants / $9,000

Effect of neck inputs on pain signals$9,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor Philip Bolton
SchemeProject Grant
RoleLead
Funding Start2002
Funding Finish2002
GNoG0181332
Type Of FundingInternal
CategoryINTE
UONY

20012 grants / $81,897

An investigation of the chiropractic vertebral subluxation hypothesis in respect of neck-evoked reflex control of limb muscles.$80,494

Funding body: Australian Spinal Research Foundation

Funding bodyAustralian Spinal Research Foundation
Project TeamAssociate Professor Philip Bolton
SchemeResearch Grant
RoleLead
Funding Start2001
Funding Finish2001
GNoG0179708
Type Of FundingDonation - Aust Non Government
Category3AFD
UONY

Movement & Sensation, Cairns 2-6 September 2001$1,403

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor Philip Bolton
SchemeTravel Grant
RoleLead
Funding Start2001
Funding Finish2001
GNoG0181434
Type Of FundingInternal
CategoryINTE
UONY

19992 grants / $10,750

Influence of a putative cervical vertebral subluxation on sympathetic nerve activity$8,800

Funding body: Australian Spinal Research Foundation

Funding bodyAustralian Spinal Research Foundation
Project TeamAssociate Professor Philip Bolton
SchemeResearch Grant
RoleLead
Funding Start1999
Funding Finish1999
GNoG0177919
Type Of FundingDonation - Aust Non Government
Category3AFD
UONY

Programming Autonomic Function during Movement. Opio, France. 2-4 September 1999$1,950

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor Philip Bolton
SchemeTravel Grant
RoleLead
Funding Start1999
Funding Finish1999
GNoG0179104
Type Of FundingInternal
CategoryINTE
UONY

19981 grants / $10,000

Grant-in-aid for Spinal Studies$10,000

Funding body: Stroud Rodeo Association Inc

Funding bodyStroud Rodeo Association Inc
Project TeamAssociate Professor Philip Bolton
SchemeGrant-In-Aid
RoleLead
Funding Start1998
Funding Finish1998
GNoG0178252
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

19971 grants / $15,500

Central nervous system response to sensory ifnormation arising from articular and peri-articular structures in the neck.$15,500

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project TeamAssociate Professor Philip Bolton
SchemeSmall Grant
RoleLead
Funding Start1997
Funding Finish1997
GNoG0176727
Type Of FundingScheme excluded from IGS
CategoryEXCL
UONY

19961 grants / $49,092

Central nervous system response to sensory information arising from articular and peri-articular structures in the neck$49,092

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor Philip Bolton
SchemeMulti-Year Project Grant Scholarship
RoleLead
Funding Start1996
Funding Finish1996
GNoG0175750
Type Of FundingInternal
CategoryINTE
UONY

19952 grants / $69,601

Functional characteristics of perivertebral and articular afferents in the neck.$62,601

Funding body: NHMRC (National Health & Medical Research Council)

Funding bodyNHMRC (National Health & Medical Research Council)
Project TeamAssociate Professor Philip Bolton
SchemeProject Grant
RoleLead
Funding Start1995
Funding Finish1995
GNoG0174552
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

95APP. Central projections of nerves from joints in the neck.$7,000

Funding body: Ramaciotti Foundations

Funding bodyRamaciotti Foundations
Project TeamAssociate Professor Philip Bolton
SchemeResearch Grant
RoleLead
Funding Start1995
Funding Finish1995
GNoG0174699
Type Of FundingAust Competitive - Non Commonwealth
Category1NS
UONY

19942 grants / $43,002

Central projections of nerves from joints in the neck.$33,002

Funding body: Australian Spinal Research Foundation

Funding bodyAustralian Spinal Research Foundation
Project TeamAssociate Professor Philip Bolton
SchemeResearch Grant
RoleLead
Funding Start1994
Funding Finish1994
GNoG0174307
Type Of FundingDonation - Aust Non Government
Category3AFD
UONY

Central projections of nerves from joints in the neck.$10,000

Funding body: Arthritis Foundation of Australia

Funding bodyArthritis Foundation of Australia
Project TeamAssociate Professor Philip Bolton
SchemeResearch Grant
RoleLead
Funding Start1994
Funding Finish1994
GNoG0173387
Type Of FundingDonation - Aust Non Government
Category3AFD
UONY
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Research Supervision

Current Supervision

CommencedResearch Title / Program / Supervisor Type
2014Role of Neck Posture in Headaches
Human Biology, Faculty of Health and Medicine
Principal Supervisor
2008Childhood Stress and Altered Psychphysiological Reactivity in Chronic Pain
Psychology, Faculty of Science and Information Technology
Co-Supervisor

Past Supervision

YearResearch Title / Program / Supervisor Type
2009Examining the Role of Astrocytes in the Pathophysiology of Hypoxic/Ischemic Damage in the Neonatal Pig Brain
Human Biology, Faculty of Health and Medicine
Co-Supervisor
2006Validity of the Doppler Velocimeter as a Pre-Manipulative Screening Tool for Vertebral Artery Blood Flow
Physiotherapy, Faculty of Health and Medicine
Co-Supervisor
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Associate Professor Philip Bolton

Position

Associate Professor
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine

Focus area

Human Physiology

Contact Details

Emailphilip.bolton@newcastle.edu.au
Phone(02) 4921 7020

Office

RoomMSB410
BuildingMedical Sciences
LocationCallaghan
University Drive
Callaghan, NSW 2308
Australia
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