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Career Summary

Biography

Professor Nick Talley is Pro Vice Chancellor of the Faculty of Health at the University of Newcastle, in Australia, and Professor of Medicine. He was formerly Chair of the Department of Internal Medicine at Mayo Clinic in Jacksonville, Florida where he held the rank of Professor of Medicine at the Mayo Clinic College of Medicine; he also held the rank of Professor of Epidemiology. Previously, Nick was the Director of the Motility Interest Group in the Division of Gastroenterology and Hepatology at Mayo Clinic, Rochester, Minnesota, and before that was the Foundation Professor of Medicine at the University of Sydney, Nepean Hospital. He currently holds adjunct research appointments as Professor at Mayo Clinic, University of North Carolina and the Karolinska Institute. He undertook his undergraduate medical degree at the University of New South Wales, and holds doctorates from his alma mater and the University of Sydney as well as a Masters degree from the University of Newcastle.

Nick is currently co-editor-in-chief of Alimentary Pharmacology & Therapeutics. Previously, he was co-editor-in-chief of the American Journal of Gastroenterology, and serves on a number of prominent editorial boards. He is a founding member and Director of the Rome Foundation, a past President of the Functional Brain-Gut Research Group, was a counselor in the American Gastroenterology Association Motility Section, and served as a member of the Board of the American College of Gastroenterology. He currently serves as a Director on the Board of the Hunter Medical Research Institute in Newcastle. He is a Fellow of the Royal Australasian College of Physicians, Royal College of Physicians (both London and Edinburgh), and the American College of Physicians. Nick is a Visiting Medical Officer at the John Hunter Hospital in Newcastle.

Nick has a deep interest in medical education and has authored a number of prominent textbooks. His popular student textbook, "Clinical Examination: A Systematic Guide to Physical Diagnosis", is in its 6th edition and is distributed worldwide.

Nick's research is primarily focused on functional gastrointestinal disorders, dyspepsia, Helicobacter pylori, gastroesophageal reflux disease, and eosinophilic disorders of the gut. He has recently described with his team a new disease entity in adults, eosinophilic duodenitis, linked to functional dyspepsia. His group has documented a genetic component in upper and lower functional bowel diseases. He has published over 700 original and review articles in the peer-reviewed literature, and he is considered one of the world's leading authorities in clinical research on the stomach. He currently has research support as a Chief Investigator from the National Health and Medical Research Council, and has been funded as a Principal Investigator (RO1) by the National Institutes of Health in the USA.

Qualifications

  • Doctor of Medicine, University of New South Wales, 31/12/1993
  • Master of Medical Science (Clinical Epidemiology), University of Newcastle, 31/12/2004
  • PhD, University of Sydney, 31/12/1987
  • Bachelor of Medicine, Bachelor of Surgery, University of New South Wales, 31/12/1979

Research

Research keywords

  • Dyspepsia
  • Gastroparesis
  • Neurogastroenteology

Research expertise

Neurogastroenteology - particularly Functional Gastrointestinal disorders, Irritable bowel syndrome, Dyspepsia, Eosinophilic Gastrointestinal disorders, Eosinophilic Oesophagitis, Gastroparesis.

Fields of Research

CodeDescriptionPercentage
111799Public Health And Health Services Not Elsewhere Classified40
110399Clinical Sciences Not Elsewhere Classified30
160599Policy And Administration Not Elsewhere Classified30

Collaboration

  • Neurogastroenteology
  • Functional gastrointestinal disorders
  • Irritable bowel syndrome
  • Dyspepsia
  • Eosinophilic Gastrointestinal disorders
  • Eosinophilic Oesophagitis
  • Gastroparesis
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Grants and Funding

Summary

Number of grants8
Total funding$3,042,356

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2014 (1 grants)

Functional dyspepsia: Characterisation of the immunopathology and testing a novel therapeutic strategy.$708,146
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Nick Talley, Professor Marjorie Walker, Associate Professor Michael Jones, Dr Nick Powell, Mrs Natasha Koloski, Professor Gerald Holtmann
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$708,14620142016
GNo:G1300107

2012 (4 grants)

The development and validation of a blood test to identify IBS.$964,172
Funding Body: Prometheus Therapeutics & Diagnostics

Project Team
Professor Nick Talley, Mrs Natasha Koloski, Associate Professor Michael Jones
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$964,17220122013
GNo:G1201086

Elucidating the role of mast cell tryptases in chronic obstructive pulmonary disease and Crohn's disease$609,879
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Phil Hansbro, Professor Nick Talley, Dr Brian Oliver
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$609,87920122014
GNo:G1100239

Usefulness of Rome III symptoms, psychological characteristics and cytokines in accurately diagnosing FGIDs.$48,000
Funding Body: Rome Foundation

Project Team
Professor Nick Talley, Associate Professor Michael Jones, Mrs Natasha Koloski, Professor Gerald Holtmann
SchemeRole
Research AwardChief Investigator
Total AmountFunding StartFunding Finish
$48,00020122012
GNo:G1101184

Novel molecular markers in children with eosinophilic oesophagitis – association with symptoms, oesophageal function and treatment response and role in disease pathogenesis$20,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Scott Nightingale, Professor Joerg Mattes, Doctor Adam Collison, Professor Nick Talley
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020122013
GNo:G1200661

2011 (3 grants)

A multi-site randomised controlled trial comparing the severity of constipation symptoms experienced by palliative care patients receiving usual care compared to those diagnosed and managed according $481,469
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Conjoint Professor Katherine Clark, Professor David Currow, Professor Nick Talley, Dr Philip Dinning, Associate Professor Lawrence Lam, Professor Patricia Davidson, Associate Professor Meera Agar, Ms Tania Shelby-James, Professor Jane Phillips
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$481,46920112013
GNo:G1001088

Natural history and current treatment of chronic constipation: An Australian population-based study$170,690
Funding Body: Janssen Cilag Pty Ltd

Project Team
Professor Nick Talley, Mrs Natasha Koloski, Associate Professor Michael Jones
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$170,69020112012
GNo:G1000977

Investigation of alternate view of the performance of a biomaker array in identifying individuals with irritable bowel syndrome$40,000
Funding Body: Prometheus Therapeutics & Diagnostics

Project Team
Professor Nick Talley
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$40,00020112011
GNo:G1100198
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Research Supervision

Number of current supervisions2
Total current UoN PhD EFTSL0.83

For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20142018PhD (Medicine)Principal SupervisorFunctional Dyspepsia and Gastroparesis in Health and Diabetes: Characterisation of Gastrointestinal Sensorimotor Patterns and Mucosal Permeability
20142017PhD(Magnetic Resonance in Med)Co-SupervisorMagnetic Resonance Spectroscopy (MRS) to Document Changes in Neurochemistry
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Professor Nicholas (Nick) Talley

Work Phone(02) 4921 5855
Email
PositionPro Vice-Chancellor
Office of the PVC Health and Medicine
Faculty of Health and Medicine
The University of Newcastle, Australia
Office
HMRI Building,
Callaghan
University Drive
Callaghan NSW 2308
Australia
URL:www.newcastle.edu.au/profile/nicholas-talley