Ms  Danielle Lang

Ms Danielle Lang

Research Academic

School of Medicine and Public Health

Career Summary

Biography

An experienced health economist with over 20 years’ experience, Danielle leads the Newcastle Evaluation Group (NEG), a multidisciplinary team renowned for their expertise in health technology assessment (HTA).

Founded in 1995, NEG is Australia's longest-standing university-based research group, contracted to provide evaluations of medicines for the Pharmaceutical Benefits Advisory Committee (PBAC), an independent expert body that recommends new medicines for listing on the Pharmaceutical Benefits Scheme (PBS).

NEG’s team brings diverse expertise in critical appraisal, medicine, pharmacy, biotechnology, health economics, and health policy, allowing them to comprehensively evaluate the clinical benefit, safety, cost-effectiveness, and financial impact of healthcare interventions.

While their work for the PBAC is confidential, the executive summaries of their reports form the basis of Public Summary Documents, which publicly outline crucial discussions regarding new medicine listings on the PBS.

NEG's work directly influences access to health technologies in Australia, especially through the PBS, which currently subsidises nearly 1,000 medicines, significantly improving the lives of Australians and costing over $15 billion annually.

Beyond the PBS, NEG has provided evaluations for the Medicare Services Advisory Committee (MSAC), the Australian Technical Advisory Group on Immunisation (ATAGI), the National Diabetes Services Scheme (NDSS), and the Agency for Care Effectiveness (ACE) in Singapore; and has conducted Post-Market Reviews of PBS-subsidised medicines, ensuring continued effectiveness and value.

Danielle has contributed to more than 200 confidential HTA reports across various domains such as cardiovascular disease, diabetes, and mental health, encompassing pharmaceuticals, vaccines, medical devices, and diagnostics, and has had reports of her scholarly work published in journals such as the Lancet and PLOS Medicine.

Since 1998, Danielle has attracted over $28 million in research funding, primarily from the Australian Department of Health and Aged Care.

Danielle has taught post-graduate health economics and economic evaluation and has developed teaching materials and conducted HTA workshops for the World Health Organization and the Singapore Ministry of Health, directly impacting healthcare decision-making on a global level.


Qualifications

  • Post Graduate Diploma in Health Economics and Eval, Monash University
  • Bachelor of Mathematics/Bachelor of Economics, University of Newcastle

Keywords

  • economic evaluation
  • economic modelling
  • health economics
  • pharmacoeconomics

Fields of Research

Code Description Percentage
380108 Health economics 100

Professional Experience

UON Appointment

Title Organisation / Department
Research Academic University of Newcastle
School of Medicine and Public Health
Australia

Teaching

Code Course Role Duration
PUBH6250 Health Economics
The University of Newcastle
Course Coordinator 1/1/2004 - 19/9/2015
PUBH6260 Clinical Economics
The University of Newcastle
Course coordinator 1/7/2003 - 19/9/2015
PUBH6290 Economic evaluation of health care
University of Newcastle
(previously PUBH6260 Clinical Economics)
Course Coordinator 1/7/2015 - 19/9/2015
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Journal article (13 outputs)

Year Citation Altmetrics Link
2022 Hinwood M, Wall L, Lang D, Balogh ZJ, Smith A, Dowsey M, et al., 'Patient and clinician characteristics and preferences for increasing participation in placebo surgery trials: a scoping review of attributes to inform a discrete choice experiment', TRIALS, 23 (2022) [C1]
DOI 10.1186/s13063-022-06277-x
Citations Scopus - 1Web of Science - 1
Co-authors Madeleine Hinwood, Laura Wall, Zsolt Balogh, Francesco Paolucci
2022 Wales K, Lang D, Rahja M, Somerville L, Laver K, Lannin NA, 'Economic Effects of Occupational Therapy Services for Adults in Acute and Subacute Care Settings: A Systematic Review.', Am J Occup Ther, 76 (2022) [C1]
DOI 10.5014/ajot.2022.049078
Citations Scopus - 3Web of Science - 2
2021 Lees S, Dicker M, Ku JE, Chaganti V, Mew-Sum M, Wang N, et al., 'Impact of disease-modifying therapies on MRI and neurocognitive outcomes in relapsing-remitting multiple sclerosis: a protocol for a systematic review and network meta-analysis', BMJ OPEN, 11 (2021)
DOI 10.1136/bmjopen-2021-051509
Co-authors Madeleine Hinwood, Christopher Oldmeadow
2020 Wall L, Hinwood M, Lang D, Smith A, Bunzli S, Clarke P, et al., 'Attitudes of patients and surgeons towards sham surgery trials: a protocol for a scoping review of attributes to inform a discrete choice experiment', BMJ OPEN, 10 (2020)
DOI 10.1136/bmjopen-2019-035870
Citations Scopus - 2Web of Science - 2
Co-authors Francesco Paolucci, Madeleine Hinwood, Laura Wall
2015 Lang DL, Zhao FL, Robertson J, 'Prevention of postpartum haemorrhage: Cost consequences analysis of misoprostol in low-resource settings', BMC Pregnancy and Childbirth, (2015) [C1]

© 2015 Lang et al. Background: While inferior to oxytocin injection in both efficacy and safety, orally administered misoprostol has been included in the World Health Organization... [more]

© 2015 Lang et al. Background: While inferior to oxytocin injection in both efficacy and safety, orally administered misoprostol has been included in the World Health Organization Model List of Essential Medicines for use in the prevention of postpartum haemorrhage (PPH) in low-resource settings. This study evaluates the costs and health outcomes of use of oral misoprostol to prevent PPH in settings where injectable uterotonics are not available. Methods: A cost-consequences analysis was conducted from the international health system perspective, using data from a recent Cochrane systematic review and WHO's Mother-Baby Package Costing Spreadsheet in a hypothetical cohort of 1000 births in a mixed hospital (40 % births)/community setting (60 % births). Costs were estimated based on 2012 US dollars. Results: Using oxytocin in the hospital setting and misoprostol in the community setting in a cohort of 1000 births, instead of oxytocin (hospital setting) and no treatment (community setting), 22 cases of PPH could be prevented. Six fewer women would require additional uterotonics and four fewer women a blood transfusion. An additional 130 women would experience shivering and an extra 42 women fever. Oxytocin/misoprostol was found to be cost saving (US$320) compared to oxytocin/no treatment. Conclusions: Our findings confirm that, even though misoprostol is not the optimum choice in the prevention of PPH, misoprostol could be an effective and cost-saving choice where oxytocin is not or cannot be used due to a lack of skilled birth attendants, inadequate transport and storage facilities or where a quality assured oxytocin product is not available. These benefits need to be weighed against the large number of additional side effects such as shivering and fever, which have been described as tolerable and of short duration.

DOI 10.1186/s12884-015-0749-z
Citations Scopus - 9Web of Science - 7
2007 Salkeld G, Henry DA, Hill SR, Lang DL, Freemantle N, D'Assuncao J, 'What drives health-care spending priorities? An international survey of health-care professionals', Plos Medicine, 4 256-259 (2007) [C1]
DOI 10.1371/journal.pmed.0040094
Citations Scopus - 9Web of Science - 9
Co-authors Mddah01
2003 Henry DA, Lang DL, 'Published pharmacoeconomic analyses: science or marketing?', Internal Medicine Journal, 33 404-404 (2003) [C3]
Co-authors Mddah01
2003 Henry D, Lang D, 'Published pharmacoeconomic analyses: science or marketing?', INTERNAL MEDICINE JOURNAL, 33 403-404 (2003)
DOI 10.1046/j.1445-5994.2003.00473.x
Citations Scopus - 5Web of Science - 4
2003 Lang DL, Lopert R, Hill SR, 'Use of pharmacoeconomics in prescribing research. Part 5: modelling - beyond clinical trials', JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 28 433-439 (2003)
DOI 10.1046/j.1365-2710.2003.00458.x
Citations Scopus - 15Web of Science - 12
2003 Lopert R, Lang DL, Hill SR, 'Use of pharmacoeconomics in prescribing research. Part 3: cost-effectiveness analysis - a technique for decision-making at the margin', Journal of Clinical Pharmacy and Therapeutics, 28 243-249 (2003) [C1]
DOI 10.1046/j.1365-2710.2003.00465.x
Citations Scopus - 11Web of Science - 9
2003 Robertson J, Lang DL, Hill SR, 'Use of pharmacoeconomics in prescribing research. Part 1: costs - moving beyond the acquisition price for drugs', Journal of Clinical Pharmacy and Therapeutics, 28 73-79 (2003) [C1]
DOI 10.1046/j.1365-2710.2003.00452.x
Citations Scopus - 11Web of Science - 7
2002 Lopert R, Lang DL, Hill SR, Henry DA, 'Differential pricing of drugs: a role for cost-effectiveness analysis?', The Lancet, 359 2105-2107 (2002) [C1]
Citations Scopus - 29Web of Science - 22
Co-authors Mddah01
1999 Whitworth J, Lang DL, Henry DA, 'Cost-effectiveness Analysis in the Treatment of Hypertension: A Medical View', Clinical and Experimental Hypertension, 21(5-6) 999-1008 (1999) [C1]
Citations Scopus - 6Web of Science - 7
Co-authors Mddah01
Show 10 more journal articles

Conference (3 outputs)

Year Citation Altmetrics Link
2018 Wubishet B, Harris M, Lang D, Acharya S, Byles J, 'Rising diabetes prevalence among older Australian women', Melbourne, Australia (2018)
Co-authors Julie Byles, Melissa Harris
2017 Wubishet B, Harris M, Abbas S, Lang D, acharya S, Byles J, 'Costs of major complications of Type 2 diabetes: A systematic review', Perth, Australia (2017)
Co-authors Julie Byles, Melissa Harris
2017 Wubishet BL, Harris M, Abbas SS, Lang D, Acharya S, Byles J, 'COSTS OF MAJOR COMPLICATIONS OF TYPE 2 DIABETES: A SYSTEMATIC REVIEW', VALUE IN HEALTH (2017)
DOI 10.1016/j.jval.2017.08.446
Co-authors Melissa Harris, Julie Byles

Report (1 outputs)

Year Citation Altmetrics Link
2001 Lowe J, Bonevski B, Carless P, Lopert R, Lang D, Deveridge S, et al., 'Universal Leucodepletion of Fresh Blood Products. A report comprising systematic review, stakeholder interviews and economic analysis', Commonwealth Department of Health and Aged Care (2001)
Co-authors Billie Bonevski
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Grants and Funding

Summary

Number of grants 12
Total funding $28,180,101

Click on a grant title below to expand the full details for that specific grant.


20231 grants / $92,165

Analysing the economic and financial implications associated with expanding MBS items 12320 and 12322 for BMD testing to include patients aged 60-69 years$92,165

Funding body: Department of Health and Aged Care

Funding body Department of Health and Aged Care
Project Team Ms Danielle Lang, Mr Rob Bell, Mr Jarrod Bell, Mr Marc Bevan, Ms Lynn Goon, Doctor Madeleine Hinwood, Doctor Emily Walkom
Scheme Health Technology Assessment Services
Role Lead
Funding Start 2023
Funding Finish 2023
GNo G2300716
Type Of Funding C2100 - Aust Commonwealth – Own Purpose
Category 2100
UON Y

20211 grants / $5,985,069

The Provision Of External Evaluation Of Pharmaceutical Benefit Advisory Committee (PBAC) And Health Technology Related Submissions$5,985,069

Funding body: Department of Health and Aged Care

Funding body Department of Health and Aged Care
Project Team Ms Danielle Lang, Mr Rob Bell, Mr Marc Bevan, Ms Lynn Goon, Doctor Madeleine Hinwood, Mr Jarrod Bell, Doctor Emily Walkom
Scheme Pharmaceutical Benefits Advisory Committee (PBAC) and Health Technology Related Tender
Role Lead
Funding Start 2021
Funding Finish 2024
GNo G2100181
Type Of Funding C2100 - Aust Commonwealth – Own Purpose
Category 2100
UON Y

20201 grants / $178,382

Health Technology Assessment, Research Support and Other Services Panel$178,382

Funding body: Department of Health and Aged Care

Funding body Department of Health and Aged Care
Project Team Ms Danielle Lang, Mr Rob Bell, Mr Marc Bevan, Doctor Emily Walkom, Mr Jarrod Bell, Ms Lynn Goon, Doctor Madeleine Hinwood
Scheme Project Grant
Role Lead
Funding Start 2020
Funding Finish 2020
GNo G2000297
Type Of Funding C2100 - Aust Commonwealth – Own Purpose
Category 2100
UON Y

20181 grants / $18,667

Health Care Utilisation and Health Economics of Diabetes among Australian Women$18,667

Funding body: CEPAR (ARC Centre of Excellence in Population and Aging Health)

Funding body CEPAR (ARC Centre of Excellence in Population and Aging Health)
Project Team Emeritus Professor Julie Byles, Doctor Melissa Harris, Ms Danielle Lang, Doctor Sham Acharya
Scheme Research Supplementary Scholarship
Role Investigator
Funding Start 2018
Funding Finish 2020
GNo G1800586
Type Of Funding C2200 - Aust Commonwealth – Other
Category 2200
UON Y

20161 grants / $8,204,899

Provision of external evaluation of Pharmaceutical Benefits Advisory Committee (PBAC) and health technology related submissions$8,204,899

Funding body: Department of Health and Aged Care

Funding body Department of Health and Aged Care
Project Team Ms Danielle Lang, Mr Jarrod Bell, Mr Rob Bell, Mr Marc Bevan, Ms Lynn Goon, Doctor Madeleine Hinwood, Doctor Emily Walkom, Miss Chiara Berardi
Scheme Consultancy/Tender
Role Lead
Funding Start 2016
Funding Finish 2021
GNo G1601071
Type Of Funding C2100 - Aust Commonwealth – Own Purpose
Category 2100
UON Y

20141 grants / $53,923

Quotation for the provision of an evaluation of PBS Authority Required medicines using the Deed of Standing Offer SON 1503111 for the supply of PBS Medicines Review services$53,923

Funding body: Department of Health and Aged Care

Funding body Department of Health and Aged Care
Project Team Mr Rob Bell, Ms Danielle Lang, Mr Marc Bevan
Scheme Consultancy/Tender
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1400929
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20131 grants / $20,800

DoH Tender - Pharmaceutical Benefits Scheme (PBS) Medicines Review Panel$20,800

Funding body: Department of Health and Aged Care

Funding body Department of Health and Aged Care
Project Team Mr Marc Bevan, Mr Rob Bell, Ms Danielle Lang
Scheme Consultancy/Tender
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1300519
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20121 grants / $5,826,326

External Evaluation of PBAC Submissions RFT 086/1112 $5,826,326

Funding body: Department of Health and Aged Care

Funding body Department of Health and Aged Care
Project Team Ms Danielle Lang, Doctor Barrie Stokes, Mr Marc Bevan, Mr Rob Bell, Doctor Fei-Li Zhao
Scheme Consultancy/Tender
Role Lead
Funding Start 2012
Funding Finish 2016
GNo G1101212
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20091 grants / $4,534,474

External Evaluation of PBAC Submissions RFT 360/0708$4,534,474

Funding body: Department of Health and Aged Care

Funding body Department of Health and Aged Care
Project Team Doctor Jane Robertson, Ms Danielle Lang, Mr Rob Bell, Mr Marc Bevan
Scheme Consultancy/Tender
Role Investigator
Funding Start 2009
Funding Finish 2012
GNo G0189557
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20051 grants / $3,221,378

External Evaluation of PBAC Submissions RFP 163/0304$3,221,378

Funding body: Commonwealth Department of Health & Aged Care

Funding body Commonwealth Department of Health & Aged Care
Project Team Ms Danielle Lang, Doctor Barrie Stokes, Doctor Jane Robertson
Scheme Consultancy/Tender
Role Lead
Funding Start 2005
Funding Finish 2008
GNo G0184477
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20041 grants / $1,066

2nd International Conference on Improving Use of Medicines (ICIUM2004), 30 March - 2 April 2004, Thailand$1,066

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Ms Danielle Lang
Scheme Travel Grant
Role Lead
Funding Start 2004
Funding Finish 2004
GNo G0183884
Type Of Funding Internal
Category INTE
UON Y

20001 grants / $42,952

Local evaluation of the after hours primary medical care trial at Maitland Hospital.$42,952

Funding body: Hunter Urban Division of General Practice

Funding body Hunter Urban Division of General Practice
Project Team Conjoint Professor Dianne O'Connell, Ms Danielle Lang, Ms B Pekarsky
Scheme Research Grant
Role Investigator
Funding Start 2000
Funding Finish 2000
GNo G0180200
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y
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Research Supervision

Number of supervisions

Completed1
Current0

Past Supervision

Year Level of Study Research Title Program Supervisor Type
2021 PhD Impact of Diabetes on Women's Health Outcomes: Survival, Healthy Life Expectancy, and Health Related Quality of Life PhD (Health Economics), College of Health, Medicine and Wellbeing, The University of Newcastle Co-Supervisor
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Research Projects

Patient and Surgeon preferences for sham surgery trials 2019 -

Publications

Wall L, Hinwood M, Lang D, Smith A, Bunzli S, Clarke P, et al., 'Attitudes of patients and surgeons towards sham surgery trials: a protocol for a scoping review of attributes to inform a discrete choice experiment', BMJ OPEN, 10 (2020)

Bunzli S, Choong E, Shadbolt C, Wall L, Nelson E, Schilling C, et al., 'Placebo Surgery Controlled Trials: Do They Achieve What They Set Out To Do? A Systematic Review.', Ann Surg, 273 1102-1107 (2021) [C1]

Collaborators

Name Organisation
Doctor Madeleine Hinwood University of Newcastle
Ms Danielle Leigh Lang University of Newcastle

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Ms Danielle Lang

Position

Research Academic
School of Medicine and Public Health
College of Health, Medicine and Wellbeing

Contact Details

Email danielle.lang@newcastle.edu.au
Phone (02) 4014 3002
Fax (02) 4960 2088

Office

Room NM2.545
Building Calvary Mater Newcastle Level 5 - New Med 2
Location Mater Hospital

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