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Professor Zsolt Balogh

Professor of Surgery

School of Medicine and Public Health

Career Summary

Biography

Professor Balogh is the Discipline Head of Traumatology and leads the Traumatology Research Group at the University of Newcastle. He is also the Director of Trauma Surgery at the John Hunter Hospital and Hunter New England Local Health District. Apart from a teacher and researcher, he is an active trauma and orthopaedic surgeon with a major interest in complex polytrauma patients and pelvic and acetabulum fracture patients. As the Discipline Head of Traumatology, Professor Balogh is responsible for the Trauma curriculum at the University of Newcastle, which has formal components in years 1,3,4 and 5 in the Medical School. His research covers many areas of trauma care such as orthopaedic trauma, torso trauma and postinjury critical care. He collaborates with academic trauma centres and Universities in Europe, United States and Australia. Professor Balogh supervises the Traumatology PhD program at The University of Newcastle and clinical and research fellowship programs at the John Hunter Hospital.

Research Expertise
Objective Research Measures (May 2014): Cumulative impact factor (based on the year of publication): 411.949 H-score : 24 Citations: 2883 Clinical and laboratory research on major trauma, traumatic shock, postinjury inflammation and its complications. Clinical and laboratory research on major orthopaedic trauma. Clinical research on pelvic fractures. Clinical research on geriatric/fragility fractures. Trauma epidemiology, outcome and trauma score research.

Teaching Expertise
Professor Balogh provides undergraduate and postgraduate education in wide aspects of trauma care, orthopaedics and critical care at local, national and international levels. He has mentored many students, residents, fellows and PhD students who have won awards and scholarships in these areas: 2014 - 83rd RACS Anual Scientific Congress - Best scientified paper: Trauma Research Papers Competition (Dr Daniel McIlroy, PhD student) - Neutrophil extracellular traps formed following trauma and subsequent surgery contain mitochondrial DNA 2011- 1st Prize, Hunter Orthopedic Society Meeting, Best Paper Competition (by Dr Osamu Yoshino, PhD student) – Polytrauma model with femur fracture. 2011 – American Association for the Surgery of Trauma – Medical Student travel scholarship to attend the AAST annual meeting in Chicago, IL, USA (by Benjamin Hardy, medical student, BMed student researcher). 2011 – International Association of Trauma Surgery and Intensive Care (IATSIC) – best paper presentation, Yokohama, Japan (“Blunt polytrauma model with femur fracture” by Dr Osamu Yoshino, resident, PhD student). 2011 – International Society of Surgery – Australasian Chapter – Travelling fellowship to the International Surgical Week in Yokohama, Japan (by Dr Osamu Yoshino, resident, PhD student). 2011 – European Society of Trauma and Emergency Surgery – Young Researcher Travel Award (by Dr Nerida Butcher, senior resident) for the European Society of Trauma and Emergency Surgery conference, Milano, Italy. – Definition of Polytrauma, International consensus initiative. 2010 – 1st Prize, Australian Orthopaedic Registrar Association - Registrar Paper Competition (by Dr Nicole Williams, orthopaedic registrar). Adelaide, SA. – Outcomes of low energy hip fractures in a major trauma centre. 2010 – 1st Prize, Australian Orthopaedic Association (NSW Branch) Registrar Competition (by Dr Nicole Williams, orthopaedic registrar). Sydney, NSW. – Outcomes of low energy hip fractures in a major trauma centre. 2009 – 1st Prize, Royal Australasian College of Surgeons, Annual Trauma Registrar/Fellow Competition (by Dr Andrew Martin, trauma fellow). Adelaide, SA. – Redefinition of haemorrhagic shock for the Australian trauma registries. Delegated to Las Vegas, Nevada in 2010 for the International Competition, to represent the Asia Pacific Region. 2009- 1st Prize, Hunter Orthopedic Society Meeting, Best Paper Competition. (by Dr Laszlo Toth, Trauma Fellow) – Prediction of Arterial bleeding in haemodynamically unstable pelvic fractures. 2008 – 1st Prize, Royal Australasian College of Surgeons, Annual Scientific Congress, Best Trauma Free Paper. (by Tim Arnold, BMed Student), Hong Kong, China – The correlation of arterial and venous base deficit during trauma resuscitation. 2008 – 2nd Prize, Royal Australasian College of Surgeons, Annual Trauma Registrar/Fellow Competition (by Dr Laszlo Toth, Trauma Fellow). Melbourne, Victoria. – The safety and efficacy of pelvic binding. 2008- 1st Prize, Hunter Orthopedic Society Meeting, Best Paper Competition (by Dr Ben Nicholas, Surgical Intern) – Early total care versus damage control orthopaedics: the Australian perspective. 2007 – 1st Prize, Royal Australasian College of Surgeons, Annual Trauma Registrar/Fellow Competition (by Dr David Dewar, Orthopedic Registrar/PhD Student). Melbourne, Victoria. – The epidemiology of postinjury multiple organ failure. Delegated to Washington DC in 2008 for the International Competition, represented the Asia Pacific Region. 2007- 1st Prize, Hunter Orthopedic Society Meeting, Best Paper Competition (by Dr David Dewar, Orthopedic Registrar/PhD Student) – Postinjury MOF for the orthopedic surgeon.

Administrative Expertise
Professor Balogh is the Director of Trauma Services for the John Hunter Hospital and Hunter New England Trauma System. Discipline Head of Traumatology, University of Newcastle Year 5 Orthopaedics/Trauma Co-ordinator.

Collaborations
The Traumatology Research Group has extensive collaborations locally (John Hunter Hospital, University of Newcastle), NSW, Interstate and at International levels. Current and past key collaborating Institutions: Hunter Medical Research Institute University of NSW Queensland University of Technology National Trauma Research Institute / Monash University NSW Institute of Trauma and Injury Management University of Colorado, Denver, USA University of Texas-Houston Medical School, USA Cornell University, The Methodist Hospital, Houston, USA University of Leeds, UK University of Aachen, Germany AO Research Institute, Switzerland.

Keywords

  • Abdominal Compartment Syndrome
  • Behavioural research in trauma patients: alcohol and smoking
  • Fragility / Geriatric Fractures
  • Major Pelvic Fractures
  • Orthopaedic Trauma - timing of fracture fixation, multiple long bone fractures
  • Physiological response to trauma
  • Polytrauma
  • Postinjury Multiple Organ Failure
  • Postinjury immunology/inflammation
  • Trauma Scoring - Polytrauma Definition
  • • Orthopaedics
  • • Pelvic surgery
  • • Postinjury critical care
  • • Trauma care

Fields of Research

Code Description Percentage
110299 Cardiorespiratory Medicine and Haematology not elsewhere classified 15
110314 Orthopaedics 40
111799 Public Health and Health Services not elsewhere classified 45

Professional Experience

UON Appointment

Title Organisation / Department
Professor of Surgery University of Newcastle
School of Medicine and Public Health
Australia

Academic appointment

Dates Title Organisation / Department
1/01/2011 -  Editorial Board - The Journal of Trauma The Journal of Trauma
Australia
1/01/2010 -  Asoociate Editor - Surgical Techniques Development Journal Surgical Techniques Development Journal
Australia
1/01/2010 -  Fellow - Australian Orthopaedic Association AOA Australian Orthopaedic Association
1/01/2010 -  Associate Editor-in-Chief - International Journal of Burns and Trauma International Journal of Burns and Trauma
Australia
1/01/2010 -  Section Editor (Polytrauma) - European Journal of Trauma and Emergency Surgery European Journal of Trauma and Emergency Surgery
United States
1/05/2009 -  Professor of Traumatology University of Newcastle
School of Medicine and Public Health
Australia
1/01/2009 -  Specialty Editor (Trauma) - ANZ Journal of Surgery ANZ Journal of Surgery
Australia
1/01/2009 -  Fellow - American College of Surgeons American College of Surgeons
United States
1/01/2009 - 31/12/2009 Editorial Board - World Journal of Surgery World Journal of Surgery
Australia
1/01/2009 -  Editorial Board - Clinical Medicine Insights: Trauma and Intensive Medicine Journal Clinical Medicine Insights: Trauma and Intensive Medicine Journal
Australia
1/01/2009 -  Editorial Board - Journal of Trauma Management and Outcomes Journal of Trauma Management and Outcomes
Australia
1/01/2009 -  Membership - Western Trauma Association (USA) Western Trauma Association (USA)
United States
1/01/2008 - 31/12/2008 Editorial Board - Current Opinion in Critical Care Journal Current Opinion in Critical Care Journal
Australia
1/01/2008 -  Editorial Board - World Journal of Emergency Surgery World Journal of Emergency Surgery
Australia
1/01/2007 -  Editorial Board - Turkish Journal of Trauma and Emergency Surgery Turkish Journal of Trauma and Emergency Surgery
Australia
1/01/2006 -  Fellow - Royal Australasian College of Surgeons Royal Australasian College of Surgeons
1/01/2005 -  Director of Trauma Services Hunter New England Health
John Hunter Hospital
Australia
1/01/2005 -  Editorial Board - Injury Journal Injury Journal
Australia

Membership

Dates Title Organisation / Department
1/01/2010 -  Membership - American Association for the Surgery of Trauma American Association for the Surgery of Trauma
United States
1/01/2010 -  Membership - American Academy of Orthopaedic Surgeons American Academy of Orthopaedic Surgeons
United States
1/01/2010 -  Membership - Australasian Trauma Society Australasian Trauma Society
Australia
1/01/2010 -  Membership - Australian Medical Association Australian Medical Association
Australia
1/01/2009 -  Executive Member - Australian and New Zealand Association for the Surgery of Trauma Australian and New Zealand Association for the Surgery of Trauma
Australia
1/01/2009 -  Membership - AO Foundation/AO Trauma (AO Trustee for Australia) AO Foundation/AO Trauma (AO Trustee for Australia)
Australia
1/01/2009 -  Membership - Hunter Medical Research Institute University of Newcastle
Hunter Medical Research Institute
Australia
1/01/2009 -  Membership - Hunter Surgical Society Hunter Surgical Society
Australia
1/01/2009 -  Membership - International Association of Trauma Surgery and Intensive Care International Association of Trauma Surgery and Intensive Care
Australia
1/01/2009 -  Membership - International Society of Surgery International Society of Surgery
Australia
1/01/2009 -  Membership - Orthopaedic Trauma Association (USA) Orthopaedic Trauma Association
United States
1/01/2009 -  Membership - RACS Section of Academic Surgery Royal Australasian College of Surgeons (RACS)
Australia
1/01/2009 -  Secretary and Executive Member - World Society of Abdominal Compartment Syndrome World Society of Abdominal Compartment Syndrome
Australia
1/01/2008 -  Membership - Hunter Orthopaedic Society Hunter Orthopaedic Society
Australia
1/01/2008 -  Membership - Hungarian Society of Traumatology Hungarian Society of Traumatology
Hungary
1/01/2008 -  Membership - RACS Trauma Education and Curriculum Development Sub-Committee Royal Australasian College of Surgeons (RACS)
Australia
1/01/2008 -  Secretary and Executive Member - Australian Orthopaedic Trauma Society Australian Orthopaedic Trauma Society
Australia
1/01/2005 -  Membership - RACS Definitive Surgical Trauma Management Course Committee Royal Australasian College of Surgeons (RACS)
Australia
1/01/2005 -  Membership - RACS Trauma Committee Royal Australasian College of Surgeons (RACS)
Australia
1/01/2003 -  Membership - European Association for Trauma and Emergency Surgery European Association for Trauma and Emergency Surgery
Austria

Professional appointment

Dates Title Organisation / Department
1/01/2005 -  Orthopaedic Trauma Surgeon and, Trauma Surgeon Hunter New England Area Health Service
John Hunter Hospital
Australia

Awards

Recognition

Year Award
2014 Excellence in Reviewing
Injury - International Journal of the Care of the Injured
2014 Official AOTrauma Fellowship Host Centre
John Hunter Hospital
2013 Award for best paper 2010-2011 World Journal of Surgery
International Society of Surgery (ISS) Société Internationale de Chirurgie (SIC)
2013 Best Surgeon Innovator
AO Foundation
2012 Certificate of Outstanding Service
Royal Australasian College of Surgeons (RACS)
2011 Honorary Professor
Peking University
2006 Orthopedic consultant/educator of the year
Hunter New England Health

Research Award

Year Award
2014 Orthopaedic Research Award
AOA Australian Orthopaedic Association
2014 John Mitchell Crouch Fellowship
Royal Australasian College of Surgeons
2010 Research Excellence Award
University of Newcastle
2008 Staff Achievement Awards
Hunter New England Health
2005 Travelling Fellowship
Royal Australasian College of Surgeons (RACS)

Invitations

Distinguished Visitor

Year Title / Rationale
2011 Abdominal compartment syndrome: From recognition to the solution
Organisation: Habilitation Lecture Series, University of Szeged Description: .
2011 The organisation of polytrauma care: Initial management, priorities
Organisation: Habilitation Lecture Series, University of Szeged Description: .
2011 Trauma nursing in Australia
Organisation: Annual Congress of the Dutch Trauma Society Description: .
2011 Abdominal compartment syndrome: From recognition to solution
Organisation: Annual Congress of the Dutch Trauma Society Description: .
2011 Damage control orthopaedics: pushing the envelope
Organisation: Annual Congress of the Dutch Trauma Society Description: .
2011 How to develop a trauma research centre
Organisation: Annual Congress of the Dutch Trauma Society Description: .
2011 The development of a trauma centre: The Newcastle Experience
Organisation: Journal Club of the Gold Coast Hospital Orthopaedic Surgeons Description: .
2011 The management of haemodynamically unstable pelvic fractures
Organisation: Annual Trauma Congress of the Peking University Description: .
2009 Recent advancements on the management of patients with haemodynamically unstable pelvic fractures
Organisation: National Institute of Traumatology, Peterfy Hospital and Trauma Center - Institutional Trauma Course Description: .
2009 Penetrating trauma cases presentation
Organisation: Definitive Surgical Trauma Care Workshop on Trauma to Visceral Organs, European Society for Trauma and Emergency Surgery Description: .
2009 Damage control, packing, abdominal compartment syndrome
Organisation: Definitive Surgical Trauma Care Workshop on Trauma to Visceral Organs, European Society for Trauma and Emergency Surgery Description: .
2009 Blunt trauma case presentation
Organisation: Definitive Surgical Trauma Care Workshop on Trauma to Visceral Organs, European Society for Trauma and Emergency Surgery Description: .
2009 Which diagnostic steps are necessary in visceral trauma?
Organisation: Definitive Surgical Trauma Care Workshop on Trauma to Visceral Organs, European Society for Trauma and Emergency Surgery Description: .

Keynote Speaker

Year Title / Rationale
2011 The American Trauma System
Organisation: Polytrauma Management Beyond ATLS Description: .
2011 Haemorrhage control versus cranial decompression? Debate for haemorrhage control
Organisation: Polytrauma Management Beyond ATLS Description: .
2011 Priorities in lifesaving surgical interventions: What comes first?
Organisation: Polytrauma Management Beyond ATLS Description: .
2010 Epidemiology of traumatic deaths: Comprehensive population-based assessment
Organisation: 10th International Summit on Trauma, Shock, Infection and Sepsis (TSIS) Description: .
2010 The definition of Polytrauma
Organisation: Aachen Polytrauma Summit Description: .
2009 Immune modulation in trauma
Organisation: Pre-Congress Instructional Course on Surgical Infections, 10th European Congress of Trauma and Emergency Surgery Description: .
2009 Trauma and infection
Organisation: Pre-Congress Instructional Course on Surgical Infections, 10th European Congress of Trauma and Emergency Surgery Description: .
2009 Prediction of ACS
Organisation: 4th World Congress Abdominal Compartment Syndrome Description: .
2009 When to open/close the abdomen: Interactive case presentations with Dr Ivatury
Organisation: 4th World Congress Abdominal Compartment Syndrome Description: .
2008 Ankle fractures
Organisation: International Fall Trauma Symposium Description: .
2008 Early management and decision making
Organisation: International Fall Trauma Symposium Description: .
2008 Abdominal compartment syndrome: Diagnosis and treatment
Organisation: XXXVI Biennial World Congress of the International College of Surgeons Description: .
2007 Abdominal compartment syndrome complicating infection
Organisation: 7th World Congress on Trauma, Shock, Inflammation and Sepsis Description: .
2007 Post injury multiple organ failure: History, current trends and future directions
Organisation: Injury 2007 Description: .
2007 Management of the complex pelvic fracture
Organisation: Injury 2007 Description: .

Speaker

Year Title / Rationale
2012 Damage control orthopaedics: Quo vadis
Organisation: 12th Co-operative Course Polytrauma Management - Beyond ATLAS Description: .
2012 Current management of unstable pelvic fractures
Organisation: 4th Annual Southwest Trauma & Acute Care Symposium Description: .
2012 A review of causes for mortality in hip fracture patients
Organisation: Whitlam Orthopaedic Research Centre Symposium Description: .
2012 Cornerstones of "The Golden Standard" in Trauma management
Organisation: Partnerships to Better Patient Outcomes Description: .
2012 The development of the trauma system in the Hunter and well beyond
Organisation: Critical Care Conference in the Vineyards Description: .
2012 Haemodynamically unstable pelvic fractures
Organisation: Kyungpook National University Hospital Description: .
2011 Consensus on Polytrauma - no physiological parameters needed for the definition
Organisation: European Society of Trauma and Emergency Surgery Description: .
2011 Damage control surgery is an outdated, overused concept
Organisation: SWAN Trauma Conference Description: .
2011 Damage control vs definitive care: where is the line?
Organisation: 5th World Congress Abdominal Compartment Syndrome Description: .
2011 Postinjury abdominal compartment syndrome
Organisation: International Association of Trauma and Intensive Care Description: .
2010 Ethics in acute care
Organisation: Medical Leadership Development Seminar, University of Newcastle Description: .
2006 Invited Instructor/Speaker
Organisation: National Trauma Management Course, National Academy of Traumatology Description: .
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (9 outputs)

Year Citation Altmetrics Link
2013 Balogh ZJ, Yoshino O, 'Abdominal compartment syndrome', Common Problems in Acute Care Surgery, Springer New York 445-450 (2013)

Abdominal compartment syndrome (ACS) is a life-threatening condition associated with organ dysfunction/failure due to increased intra-abdominal pressure (IAP). Based on consensus,... [more]

Abdominal compartment syndrome (ACS) is a life-threatening condition associated with organ dysfunction/failure due to increased intra-abdominal pressure (IAP). Based on consensus, ACS is defined as IAP > 20 mmHg and vital organ dysfunction related to it. Increased IAP without organ dysfunction is considered intra-abdominal hypertension (IAH) and graded (I: 12-15 mmHg, II: 16-20 mmHg, III: 21-25 mmHg, IV: >25 mmHg) [1, 2]. The physiological compromise from increased IAP was first described in the nineteenth century in the clinical setting, and then during the early twentieth century in the laboratory setting [3, 4]. The avoidance of increased IAP, and its resultant catastrophic respiratory and renal function consequences, was first advocated by pediatric surgeons using silos to close large omphaloceles [5]. The term ACS was coined by Fietsam et al. who described the syndrome as a complication of the management of ruptured abdominal aortic aneurisms [6]. Damage control surgery made it possible to salvage patients from previously irreversible traumatic shock and resuscitate them to reach the intensive care unit (ICU) in critical condition [7, 8]. Among these severe shock/trauma patients, ACS was a frequent cause of death, unplanned returns to the operating room, and prolonged ICU stays [9, 10]. Based on the trauma experience, acute care surgeons have applied the principles of prevention, recognition, and management to acute general surgical patients. In the same time, most surgical and nonsurgical specialties have reported on ACS from their experience.

DOI 10.1007/978-1-4614-6123-4_36
Citations Scopus - 1
2012 Balogh ZJ, Yoshino O, Sugrue M, 'Abdominal compartment syndrome', Penetrating Trauma: A Practical Guide on Operative Technique and Peri-operative Management, Springer-Verlag, Heidelberg 401-406 (2012) [B2]
2012 Bendinelli C, Balogh ZJ, 'Laparoscopy in trauma patients', Advances in Laparoscopic Surgery, InTech, Rijeka, Croatia 43-52 (2012) [B2]
2011 Sucher JF, Balogh ZJ, Moore FA, 'Abdominal compartment syndrome and management of the open abdomen', Current Surgical Therapy, Elsevier, Philadelphia, PA 1001-1007 (2011) [B2]
2007 Balogh Z, McKinley BA, Moore FA, 'Multiple organ Failure', Perioperative fluid therapy, Informa Healthcare, New York, United States 525-536 (2007) [B2]
2006 Balogh ZJ, Moore FA, Goettler CE, Rotondo MF, Schwab CW, Kaplan MJ, 'Surgical management of abdominal compartment syndrome', Abdominal Compartment Syndrome, Landes Bioscience, Georgetown, Texas 266-296 (2006) [B2]
2006 Balogh ZJ, Moore FA, 'Postinjury secondary abdominal compartment syndrome', Abdominal Compartment Syndrome, Landes Bioscience, Georgetown, Texas 170-177 (2006) [B2]
2005 Balogh ZJ, Moore FA, 'Abdominal compartment syndrome', Textbook of Critical Care, Elsevier, Philadelphia, PA 1469-1475 (2005) [B2]
2000 Balogh ZJ, Wolfard A, Szalay L, Simonka JA, Boros M, 'The effects of low-molecular-weight heparin on leukocyte-endothelial cell interactions in hemorrhagic shock and reperfusion.', Trauma, Shock, Inflammation and Sepsis, pathophysiology immune consequences and therapy, Monduzzi Editore, Milan, Italy 315-319 (2000) [B1]
Show 6 more chapters

Journal article (173 outputs)

Year Citation Altmetrics Link
2015 McIlroy DJ, Bigland M, White AE, Hardy BM, Lott N, Smith DW, Balogh ZJ, 'Cell necrosis-independent sustained mitochondrial and nuclear DNA release following trauma surgery.', J Trauma Acute Care Surg, 78 282-288 (2015)
DOI 10.1097/TA.0000000000000519
Citations Web of Science - 2
Co-authors Douglas Smith
2015 Tarrant SM, Balogh ZJ, 'Low-energy falls.', ANZ J Surg, 85 202-203 (2015)
DOI 10.1111/ans.13002
2015 Gunning A, Voskens F, van Heijl M, Balogh Z, Maier R, Leenen L, 'Global Patterns and Outcomes of Patients With Traumatic Brain Injury', JOURNAL OF HEAD TRAUMA REHABILITATION, 30 E87-E87 (2015)
2015 Gunning AC, Lansink KWW, van Wessem KJP, Balogh ZJ, Rivara FP, Maier RV, Leenen LPH, 'Demographic Patterns and Outcomes of Patients in Level I Trauma Centers in Three International Trauma Systems', World Journal of Surgery, (2015)

Introduction: Trauma systems were developed to improve the care for the injured. The designation and elements comprising these systems vary across countries. In this study, we hav... [more]

Introduction: Trauma systems were developed to improve the care for the injured. The designation and elements comprising these systems vary across countries. In this study, we have compared the demographic patterns and patient outcomes of Level I trauma centers in three international trauma systems. Methods: International multicenter prospective trauma registry-based study, performed in the University Medical Center Utrecht (UMCU), Utrecht, the Netherlands, John Hunter Hospital (JHH), Newcastle, Australia, and Harborview Medical Center (HMC), Seattle, the United States. Inclusion: patients =18 years, admitted in 2012, registered in the institutional trauma registry. Results: In UMCU, JHH, and HMC, respectively, 955, 1146, and 4049 patients met the inclusion criteria of which 300, 412, and 1375 patients with Injury Severity Score (ISS) > 15. Mean ISS was higher in JHH (13.5; p < 0.001) and HMC (13.4; p < 0.001) compared to UMCU (11.7). Unadjusted mortality: UMCU = 6.5 %, JHH = 3.6 %, and HMC = 4.8 %. Adjusted odds of death: JHH = 0.498 [95 % confidence interval (CI) 0.303¿0.818] and HMC = 0.473 (95 % CI 0.325¿0.690) compared to UMCU. HMC compared to JHH was 1.002 (95 % CI 0.664¿1.514). Odds of death patients ISS > 15: JHH = 0.507 (95 % CI 0.300¿0.857) and HMC = 0.451 (95 % CI 0.297¿0.683) compared to UMCU. HMC = 0.931 (95 % CI 0.608¿1.425) compared to JHH. TRISS analysis: UMCU: Ws = 0.787, Z = 1.31, M = 0.87; JHH, Ws = 3.583, Z = 6.7, M = 0.89; HMC, Ws = 3.902, Z = 14.6, M = 0.84. Conclusion: This study demonstrated substantial differences across centers in patient characteristics and mortality, mainly of neurological cause. Future research must investigate whether the outcome differences remain with nonfatal and long-term outcomes. Furthermore, we must focus on the development of a more valid method to compare systems.

DOI 10.1007/s00268-015-3162-x
2015 Kirkpatrick AW, De Waele JJ, De Laet I, De Keulenaer B, D'Amours S, Björck M, et al., 'WSACS-The Abdominal Compartment Society. A Society dedicated to the study of the physiology and pathophysiology of the abdominal compartment and its interactions with all organ systems', Anaesthesiology Intensive Therapy, 47 191-194 (2015)
DOI 10.5603/AIT.a2015.0024
2015 Lukins TR, Ferch R, Balogh ZJ, Hansen MA, 'Cervical spine immobilization following blunt trauma: a systematic review of recent literature and proposed treatment algorithm.', ANZ J Surg, (2015)
DOI 10.1111/ans.13221
2014 Butcher NE, D'Este C, Balogh ZJ, 'The quest for a universal definition of polytrauma: a trauma registry-based validation study.', J Trauma Acute Care Surg, 77 620-623 (2014) [C1]
DOI 10.1097/TA.0000000000000404
Co-authors Catherine Deste
2014 Sartelli M, Catena F, Ansaloni L, Coccolini F, Corbella D, Moore EE, et al., 'Complicated intra-abdominal infections worldwide: The definitive data of the CIAOW Study', World Journal of Emergency Surgery, 9 (2014) [C1]

The CIAOW study (Complicated intra-abdominal infections worldwide observational study) is a multicenter observational study underwent in 68 medical institutions worldwide during a... [more]

The CIAOW study (Complicated intra-abdominal infections worldwide observational study) is a multicenter observational study underwent in 68 medical institutions worldwide during a six-month study period (October 2012-March 2013). The study included patients older than 18 years undergoing surgery or interventional drainage to address complicated intra-abdominal infections (IAIs).1898 patients with a mean age of 51.6 years (range 18-99) were enrolled in the study. 777 patients (41%) were women and 1,121 (59%) were men. Among these patients, 1,645 (86.7%) were affected by community-acquired IAIs while the remaining 253 (13.3%) suffered from healthcare-associated infections. Intraperitoneal specimens were collected from 1,190 (62.7%) of the enrolled patients.827 patients (43.6%) were affected by generalized peritonitis while 1071 (56.4%) suffered from localized peritonitis or abscesses.The overall mortality rate was 10.5% (199/1898).According to stepwise multivariate analysis (PR = 0.005 and PE = 0.001), several criteria were found to be independent variables predictive of mortality, including patient age (OR = 1.1; 95%CI = 1.0-1.1; p < 0.0001), the presence of small bowel perforation (OR = 2.8; 95%CI = 1.5-5.3; p < 0.0001), a delayed initial intervention (a delay exceeding 24 hours) (OR = 1.8; 95%CI = 1.5-3.7; p < 0.0001), ICU admission (OR = 5.9; 95%CI = 3.6-9.5; p < 0.0001) and patient immunosuppression (OR = 3.8; 95%CI = 2.1-6.7; p < 0.0001). © 2014 Sartelli et al.; licensee BioMed Central Ltd.

DOI 10.1186/1749-7922-9-37
Citations Scopus - 8Web of Science - 6
2014 Weber DG, Bendinelli C, Balogh ZJ, 'Damage control surgery for abdominal emergencies', British Journal of Surgery, 101 (2014) [C1]

Background: Damage control surgery is a management sequence initiated to reduce the risk of death in severely injured patients presenting with physiological derangement. Damage co... [more]

Background: Damage control surgery is a management sequence initiated to reduce the risk of death in severely injured patients presenting with physiological derangement. Damage control principles have emerged as an approach in non-trauma abdominal emergencies in order to reduce mortality compared with primary definitive surgery. Methods: A PubMed/MEDLINE literature review was conducted of data available over the past decade (up to August 2013) to gain information on current understanding of damage control surgery for abdominal surgical emergencies. Future directions for research are discussed. Results: Damage control surgery facilitates a strategy for life-saving intervention for critically ill patients by abbreviated laparotomy with subsequent reoperation for delayed definitive repair after physiological resuscitation. The six-phase strategy (including damage control resuscitation in phase 0) is similar to that for severely injured patients, although non-trauma indications include shock from uncontrolled haemorrhage or sepsis. Minimal evidence exists to validate the benefit of damage control surgery in general surgical abdominal emergencies. The collective published experience over the past decade is limited to 16 studies including a total of 455 (range 3-99) patients, of which the majority are retrospective case series. However, the concept has widespread acceptance by emergency surgeons, and appears a logical extension from pathophysiological principles in trauma to haemorrhage and sepsis. The benefits of this strategy depend on careful patient selection. Damage control surgery has been performed for a wide range of indications, but most frequently for uncontrolled bleeding during elective surgery, haemorrhage from complicated gastroduodenal ulcer disease, generalized peritonitis, acute mesenteric ischaemia and other sources of intra-abdominal sepsis. Conclusion: Damage control surgery is employed in a wide range of abdominal emergencies and is an increasingly recognized life-saving tactic in emergency surgery performed on physiologically deranged patients. © 2013 BJS Society Ltd.

DOI 10.1002/bjs.9360
Citations Scopus - 8Web of Science - 4
2014 Easton R, Balogh ZJ, 'Peri-operative changes in serum immune markers after trauma: A systematic review', Injury, (2014) [C1]
Citations Scopus - 7Web of Science - 4
2014 Lumsdaine W, Easton RM, Lott NJ, White A, Malmanche TLD, Lemmert K, et al., 'Neutrophil oxidative burst capacity for peri-operative immune monitoring in trauma patients', Injury, (2014) [C1]

Background: Post injury immune dysfunction can result in serious complications. Measurement of biomarkers may guide the optimal timing of surgery in clinically borderline patients... [more]

Background: Post injury immune dysfunction can result in serious complications. Measurement of biomarkers may guide the optimal timing of surgery in clinically borderline patients and therefore prevent complications. Aim: peri-operative measurement of neutrophil oxidative burst capacity as an indicator of the immune response to major orthopaedic surgical procedures. Methods: Prospective cohort study of trauma patients aged =16 yrs with pelvic, acetabular, femoral shaft or tibial shaft fractures requiring surgical intervention. Blood samples were taken immediately pre-op and at 30 min, 7, 24 and 72-96 h post-operatively. Neutrophil oxidative burst capacity was measured both with and without stimulation by formyl-methionyl-leucyl-phenylalanine (fMLP, a chemotactic factor). Clinical outcomes measured were mortality, length of stay, MOF, pneumonia, acute respiratory distress syndrome (ARDS) and sepsis. Results: 100 consecutive orthopaedic trauma patients were enrolled over a 16 month period. 78% were male, with a mean age of 42 ± 18 years and an average ISS of 19 ± 13. Neutrophil oxidative burst capacity was significantly elevated at 7 h (p = 0.006) and 24 h (p = 0.022) post operatively. Patients who developed infective complications (pneumonia and sepsis) had higher levels of oxidative burst capacity pre-operatively (pneumonia: 1.52 ± 0.93 v 0.99 ± 0.66 p = 0.032, sepsis: 1.39 ± 0.86 v 0.97 ± 0.56 p = 0.024) and at 24 h post op (pneumonia: 2.72 ± 2.38 v 1.12 ± 0.63 p = <0.001, sepsis: 2.16 ± 2.09 v 1.10 ± 0.54 p = <0.001). When analysed by operation type, no statistical difference was seen between major and minor operations. No correlation was found between length of stay, length of ICU stay, ISS or age and neutrophil oxidative burst capacity at any time point. Conclusions: Neutrophil oxidative burst capacity response to orthopaedic trauma surgery is associated with the infective post injury complications. There was no correlation between magnitude of injury or operation and oxidative burst capacity. These results are promising for the development of tools for prediction of post-operative complications and guidance for optimal timing for surgical intervention. © 2014 Elsevier Ltd. All rights reserved.

DOI 10.1016/j.injury.2014.04.019
2014 Tay W-H, de Steiger R, Richardson M, Gruen R, Balogh ZJ, 'Health outcomes of delayed union and nonunion of femoral and tibial shaft fractures', Injury, (2014) [C1]

Introduction: Knowledge about the functional consequences of lower limb long bone fractures is helpful to inform patients, clinicians and employers about their recovery process an... [more]

Introduction: Knowledge about the functional consequences of lower limb long bone fractures is helpful to inform patients, clinicians and employers about their recovery process and prognosis. This study aims to describe the epidemiology and health outcomes of femoral and tibial shaft fractures treated at two level I trauma centres, by comparing the differences between patients with delayed union or nonunion and patients with union. Patients and methods: An analysis of registry data over two years, supplemented with medical record review, was conducted. Fracture healing was retrospectively assessed by clinical and radiological evidence of union, and the need for surgical intervention. SF-12 scores, and work and pain status were prospectively recorded at six and twelve months post injury. Results: 285 fractures progressed to union and 138 fractures developed delayed union or nonunion. There was a significant difference between the two cohorts with regards to the mechanism of injury, association with multi-trauma, open fractures, grade of Gustilo classification, patient fund source, smoking status and presence of comorbidities. The SF-12 physical component score was less than 50 at both six and twelve months with improvement in the union group, but not in the delayed union or nonunion group. 72% of patients with union had returned to work at one year, but 54% continued to have pain. The difference compared to patients with delayed union or nonunion was significant. Discussion: Even patients whose fractures unite in the expectant time-frame will have residual physical disability. Patients with delayed union or nonunion have still poorer outcomes, including ongoing problems with returning to work and pain. It is important to educate patients about their injury so that they have realistic expectations. This is particularly relevant given that the patients most likely to sustain femoral or tibial shaft fractures are working-age healthy adults, and up to a third of fractures may develop delayed union or nonunion. Conclusion: Despite modern treatment, the patient-reported outcomes of lower limb long bone shaft fractures do not return to normal at one year. Patients with delayed union or nonunion can expect poorer outcomes. © 2014 Elsevier Ltd. All rights reserved.

DOI 10.1016/j.injury.2014.06.025
2014 Tay W-H, De Steiger R, Richardson M, Gruen R, Balogh ZJ, 'Health outcomes of delayed union and nonunion of femoral and tibial shaft fractures', Injury, 45 1653-1658 (2014) [C1]

Introduction: Knowledge about the functional consequences of lower limb long bone fractures is helpful to inform patients, clinicians and employers about their recovery process an... [more]

Introduction: Knowledge about the functional consequences of lower limb long bone fractures is helpful to inform patients, clinicians and employers about their recovery process and prognosis. This study aims to describe the epidemiology and health outcomes of femoral and tibial shaft fractures treated at two level I trauma centres, by comparing the differences between patients with delayed union or nonunion and patients with union. Patients and methods: An analysis of registry data over two years, supplemented with medical record review, was conducted. Fracture healing was retrospectively assessed by clinical and radiological evidence of union, and the need for surgical intervention. SF-12 scores, and work and pain status were prospectively recorded at six and twelve months post injury. Results: 285 fractures progressed to union and 138 fractures developed delayed union or nonunion. There was a significant difference between the two cohorts with regards to the mechanism of injury,association with multi-trauma, open fractures, grade of Gustilo classification, patient fund source, smoking status and presence of comorbidities. The SF-12 physical component score was less than 50 at both six and twelve months with improvement in the union group, but not in the delayed union or nonunion group. 72% of patients with union had returned to work at one year, but 54% continued to have pain. The difference compared to patients with delayed union or nonunion was significant. Discussion: Even patients whose fractures unite in the expectant time-frame will have residual physical disability. Patients with delayed union or nonunion have still poorer outcomes, including ongoing problems with returning to work and pain. It is important to educate patients about their injury so that they have realistic expectations. This is particularly relevant given that the patients most likely to sustain femoral or tibial shaft fractures are working-age healthy adults, and up to a third of fractures may develop delayed union or nonunion. Conclusion: Despite modern treatment, the patient-reported outcomes of lower limb long bone shaft fractures do not return to normal at one year. Patients with delayed union or nonunion can expect poorer outcomes.

DOI 10.1016/j.injury.2014.06.025
2014 Balogh ZJ, Lumsdaine W, Moore EE, Moore FA, 'Postinjury abdominal compartment syndrome: from recognition to prevention', LANCET, 384 1466-1475 (2014) [C1]
Citations Scopus - 2
2014 Verbeek DO, Sugrue M, Balogh Z, Cass D, Civil I, Harris I, et al., 'Erratum to: Acute Management of Hemodynamically Unstable Pelvic Trauma Patients: Time for a Change? Multicenter Review of Recent Practice', World Journal of Surgery, (2014) [O1]
DOI 10.1007/s00268-014-2657-1
2014 McIlroy DJ, Jarnicki AG, Au GG, Lott N, Smith DW, Hansbro PM, Balogh ZJ, 'Mitochondrial DNA neutrophil extracellular traps are formed after trauma and subsequent surgery', Journal of Critical Care, 29 1133.e1-1133.e5 (2014)
DOI 10.1016/j.jcrc.2014.07.013
Co-authors Douglas Smith, Gough Au, Philip Hansbro
2014 McIlroy DJ, Jarnicki AG, Au GG, Lott N, Smith DW, Hansbro PM, Balogh ZJ, 'Mitochondrial DNA neutrophil extracellular traps are formed after trauma and subsequent surgery', Journal of Critical Care, 29 1133.e1-1133.e5 (2014) [C1]

Introduction: Neutrophil extracellular traps (NETs) have not been demonstrated after trauma and subsequent surgery. Neutrophil extracellular traps are formed from pure mitochondri... [more]

Introduction: Neutrophil extracellular traps (NETs) have not been demonstrated after trauma and subsequent surgery. Neutrophil extracellular traps are formed from pure mitochondrial DNA (mtDNA) under certain conditions, which is potently proinflammatory. We hypothesized that injury and orthopedic trauma surgery would induce NET production with mtDNA as a structural component. Methods: Neutrophils were isolated 8 trauma patients requiring orthopedic surgery postinjury and up to 5 days postoperatively. Four healthy volunteers provided positive and negative controls. Total hip replacement patients acted as an uninjured surgical control group. Neutrophil extracellular traps were visualized with DNA (Hoechst 33342TM/Sytox Green/MitoSox/MitoTracker) stains using live cell fluorescence microscopy with downstream quantitative polymerase chain reaction analysis of DNA composition. Results: Neutrophil extracellular traps were present after injury in all 8 trauma patients. They persisted for 5 days postoperatively. Delayed surgery resulted in NET resolution, but they reformed postoperatively. Total hip replacement patients developed NETs postoperatively, which resolved by day 5. Quantitative polymerase chain reaction analysis of NET-DNA composition revealed that NETs formed after injury and surgery were made of mtDNA with no detectable nuclear DNA component. Conclusions: Neutrophil extracellular traps formed after major trauma and subsequent surgery contain mtDNA and represent a novel marker of heightened innate immune activation. They could be considered when timing surgery after trauma to prevent systemic NET-induced inflammatory complications.

DOI 10.1016/j.jcrc.2014.07.013
Citations Scopus - 3
Co-authors Gough Au, Philip Hansbro, Douglas Smith
2014 Toth L, King KL, McGrath B, Balogh ZJ, 'Factors associated with pelvic fracture-related arterial bleeding during trauma resuscitation: A prospective clinical study', Journal of Orthopaedic Trauma, 28 489-495 (2014) [C1]
DOI 10.1097/BOT.0000000000000056
2014 Neptune D, Bonevski B, Enninghorst N, Balogh ZJ, 'The prevalence of smoking and interest in quitting among surgical patients with acute extremity fractures', Drug and Alcohol Review, (2014) [C1]

Introduction and Aims: We studied the prevalence of smoking, the effect of hospital stay on motivation to quit and the exposure to smoking cessation advice in orthopaedic patients... [more]

Introduction and Aims: We studied the prevalence of smoking, the effect of hospital stay on motivation to quit and the exposure to smoking cessation advice in orthopaedic patients who required surgical intervention for acute extremity fractures. Design and Methods: This cross-sectional study involved a self-administered pen-and-paper survey assessing smoking status, interest and motivation to quit smoking, and current advice to quit among a consecutive cohort of patients aged 18-65 years old with acute extremity fractures. These patients were admitted to the John Hunter Hospital Level 1 trauma facility in New South Wales, Australia, for surgical intervention over a three month period. Results: A total of 183 patients (response rate 98%) completed the survey. Sixty-eight patients (37.2%) reported a current smoking habit. The prevalence of smoking was 42.2% among males and 25.5% among females. A total of 40% of smokers reported that they had not received advice to quit from medical staff during hospital admission. Prior to admission, 12.1% of smokers were interested in smoking cessation; this percentage increased to 26.8% post-admission. Discussion and Conclusions: The prevalence of smoking among surgical patients with extremity fractures was found to be more than twice the prevalence of the population of New South Wales. Hospital admission had a positive impact on the patient's interest in smoking cessation. Our study suggests that the identification of orthopaedic patients who smoke is suboptimal, and the opportunity to encourage smoking cessation during hospital admission is currently being overlooked. © 2014 Australasian Professional Society on Alcohol and other Drugs.

DOI 10.1111/dar.12170
Co-authors Billie Bonevski
2014 Balogh ZJ, 'Trauma verification: for the trauma centre or for the trauma system?', ANZ JOURNAL OF SURGERY, 84 499-500 (2014) [C3]
DOI 10.1111/ans.12573
2014 Tarrant SM, Hardy BM, Balogh ZJ, 'Repair of traumatic muscle herniation with acellular porcine collagen matrix', ANZ Journal of Surgery, 84 464-467 (2014)
DOI 10.1111/ans.12200
2014 Tarrant SM, Hardy BM, Balogh ZJ, 'Repair of traumatic muscle herniation with acellular porcine collagen matrix', ANZ Journal of Surgery, 84 464-467 (2014) [C1]

Background: Muscle hernias are uncommon clinical conditions with no uniform solution of repair. Biocompatible mesh allows for repair of hernias without the donor site morbidity an... [more]

Background: Muscle hernias are uncommon clinical conditions with no uniform solution of repair. Biocompatible mesh allows for repair of hernias without the donor site morbidity and complications from direct repair under tension. Methods: Over a 6-month period at a Level 1 Trauma centre, four consecutive symptomatic muscle hernias were identified, two in the forearm and two in the lower limb. Three resulted from high-speed motorbike accidents, one from a mining accident. All patients had hernia repair at a minimum of 4 months post accident. A 10×15cm×1.0mm sheet of acellular collagen matrix was fashioned to fit as an underlay of the fascia defect. Patients were clinically followed at the 2-, 6-, 12- and 26-week mark. Final phone contact was made 18 months post-operatively. Results: All patients were pleased with their cosmetic and functional outcomes. All patients returned to work and sport 3 months after reconstruction. Conclusion: Symptomatic hernias as a result of trauma can be safely reconstructed with a biological mesh implant. This approach can prevent complications from previously described methods and return to active lifestyles with good results. © 2013 Royal Australasian College of Surgeons.

DOI 10.1111/ans.12200
2014 Butcher NE, Balogh ZJ, 'Update on the definition of polytrauma', European Journal of Trauma and Emergency Surgery, (2014) [C1]

Purpose The definition and use of the term "polytrauma" is inconsistent and lacks validation. This article describes the historical evolution of the term and geographical differen... [more]

Purpose The definition and use of the term "polytrauma" is inconsistent and lacks validation. This article describes the historical evolution of the term and geographical differences in its meaning, examines the challenges faced in defining it adequately in the current context, and summarizes where the international consensus process is heading, in order to provide the trauma community with a validated and universally agreed upon definition of polytrauma. Conclusion A lack of consensus in the definition of "polytrauma" was apparent. According to the international consensus opinion, both anatomical and physiological parameters should be included in the definition of polytrauma. An Abbreviated Injury Scale (AIS) based anatomical definition is the most practical and feasible given the ubiquitous use of the system. Convincing preliminary data show that two body regions with AIS >2 is a good marker of polytrauma-better than other ISS cutoffs, which could also indicate monotrauma. The selection of the most accurate physiological parameters is still underway, but they will most likely be descriptors of tissue hypoxia and coagulopathy. © 2014 Springer-Verlag Berlin Heidelberg.

DOI 10.1007/s00068-014-0391-x
2014 Tarrant SM, Hardy BM, Byth PL, Brown TL, Attia J, Balogh ZJ, 'Preventable mortality in geriatric hip fracture inpatients', Bone and Joint Journal, 69B 1178-1184 (2014)
DOI 10.1302/0301-620X.96B9.32814$2.00
Citations Scopus - 1
Co-authors John Attia
2014 Tarrant SM, Hardy BM, Byth PL, Brown TL, Attia J, Balogh ZJ, 'Preventable mortality in geriatric hip fracture inpatients', Bone and Joint Journal, 69B 1178-1184 (2014) [C1]

There is a high rate of mortality in elderly patients who sustain a fracture of the hip. We aimed to determine the rate of preventable mortality and errors during the management o... [more]

There is a high rate of mortality in elderly patients who sustain a fracture of the hip. We aimed to determine the rate of preventable mortality and errors during the management of these patients. A 12 month prospective study was performed on patients aged > 65 years who had sustained a fracture of the hip. This was conducted at a Level 1 Trauma Centre with no orthogeriatric service. A multidisciplinary review of the medical records by four specialists was performed to analyse errors of management and elements of preventable mortality. During 2011, there were 437 patients aged > 65 years admitted with a fracture of the hip (85 years (66 to 99)) and 20 died while in hospital (86.3 years (67 to 96)). A total of 152 errors were identified in the 80 individual reviews of the 20 deaths. A total of 99 errors (65%) were thought to have at least a moderate effect on death; 45 reviews considering death (57%) were thought to have potentially been preventable. Agreement between the panel of reviewers on the preventability of death was fair. A larger-scale assessment of preventable mortality in elderly patients who sustain a fracture of the hip is required. Multidisciplinary review panels could be considered as part of the quality assurance process in the management of these patients.

DOI 10.1302/0301-620X.96B9.32814$2.00
Citations Scopus - 4Web of Science - 3
Co-authors John Attia
2014 Cryer HG, Rhee P, Dr H, Balogh ZJ, Sauaia A, 'Temporal trends of postinjury multiple-organ failure: Still resource intensive, morbid, and lethal DISCUSSION', JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 76 592-593 (2014) [C1]
Citations Web of Science - 1
2014 White AE, Edelman JJB, Lott N, Bannon PG, McElduff P, Curnow JL, Balogh ZJ, 'Characterization of the hypercoagulable state following severe orthopedic trauma', JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 77 231-237 (2014) [C1]
DOI 10.1097/TA.0000000000000311
2014 Pape H-C, Lefering R, Butcher N, Peitzman A, Leenen L, Marzi I, et al., 'The definition of polytrauma revisited: An international consensus process and proposal of the new 'Berlin definition'', JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 77 780-786 (2014) [C1]
DOI 10.1097/TA.0000000000000453
Citations Scopus - 2Web of Science - 2
2014 Dewar DC, White A, Attia J, Tarrant SM, King KL, Balogh ZJ, 'Comparison of postinjury multiple-organ failure scoring systems: Denver versus sequential organ failure assessment', Journal of Trauma and Acute Care Surgery, 77 624-629 (2014) [C1]

BACKGROUND: The Denver and Sequential Organ Failure Assessment (SOFA) scores have been used widely to describe the epidemiology of postinjury multiple-organ failure; however, diff... [more]

BACKGROUND: The Denver and Sequential Organ Failure Assessment (SOFA) scores have been used widely to describe the epidemiology of postinjury multiple-organ failure; however, differences in these scores make it difficult to compare incidence, duration, and mortality of multiple-organ failure. The study aim was to compare the performance of the Denver and SOFA scores with respect to the outcomes of mortality, intensive care unit length of stay (ICU LOS), and ventilator days.

DOI 10.1097/TA.0000000000000406
Co-authors John Attia
2014 McIlroy DJ, Jarnicki AG, Au GG, Lott N, Smith DW, Hansbro PM, Balogh ZJ, 'Mitochondrial DNA neutrophil extracellular traps are formed after trauma and subsequent surgery.', Journal of critical care, 29 1133.e1-1133.e5 (2014) [C1]
DOI 10.1016/j.jcrc.2014.07.013
Citations Scopus - 1
Co-authors Gough Au, Douglas Smith, Philip Hansbro
2014 Balogh ZJ, 'Publishing trauma-related topics in ANZ Journal of Surgery.', ANZ J Surg, 84 399-400 (2014) [C3]
DOI 10.1111/ans.12572
2014 Tarrant SM, Hardy BM, Byth PL, Brown TL, Attia J, Balogh ZJ, 'Preventable mortality in geriatric hip fracture inpatients', Bone and Joint Journal, 96B 1178-1184 (2014) [C1]

There is a high rate of mortality in elderly patients who sustain a fracture of the hip. We aimed to determine the rate of preventable mortality and errors during the management o... [more]

There is a high rate of mortality in elderly patients who sustain a fracture of the hip. We aimed to determine the rate of preventable mortality and errors during the management of these patients. A 12 month prospective study was performed on patients aged > 65 years who had sustained a fracture of the hip. This was conducted at a Level 1 Trauma Centre with no orthogeriatric service. A multidisciplinary review of the medical records by four specialists was performed to analyse errors of management and elements of preventable mortality. During 2011, there were 437 patients aged > 65 years admitted with a fracture of the hip (85 years (66 to 99)) and 20 died while in hospital (86.3 years (67 to 96)). A total of 152 errors were identified in the 80 individual reviews of the 20 deaths. A total of 99 errors (65%) were thought to have at least a moderate effect on death; 45 reviews considering death (57%) were thought to have potentially been preventable. Agreement between the panel of reviewers on the preventability of death was fair. A larger-scale assessment of preventable mortality in elderly patients who sustain a fracture of the hip is required. Multidisciplinary review panels could be considered as part of the quality assurance process in the management of these patients.

DOI 10.1302/0301-620X.96B9.32814
Co-authors John Attia
2013 Butcher NE, Balogh ZJ, 'The practicality of including the systemic inflammatory response syndrome in the definition of polytrauma: Experience of a level one trauma centre', INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 44 12-17 (2013) [C1]
DOI 10.1016/j.injury.2012.04.019
Citations Scopus - 4Web of Science - 4
2013 Lumsdaine W, Enninghorst N, Hardy BM, Balogh ZJ, 'Patterns of CT use and surgical intervention in upper limb periarticular fractures at a level-1 trauma centre', INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 44 471-474 (2013) [C1]
DOI 10.1016/j.injury.2012.09.028
Citations Scopus - 1Web of Science - 1
2013 Sisak K, Manolis M, Hardy BM, Enninghorst N, Bendinelli C, Balogh ZJ, 'Acute transfusion practice during trauma resuscitation: Who, when, where and why?', INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 44 581-586 (2013) [C1]
DOI 10.1016/j.injury.2012.08.031
Citations Scopus - 6Web of Science - 7
2013 Bendinelli C, Bivard A, Nebauer S, Parsons MW, Balogh ZJ, 'Brain CT perfusion provides additional useful information in severe traumatic brain injury', INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 44 1208-1212 (2013) [C1]
DOI 10.1016/j.injury.2013.03.039
Citations Scopus - 3Web of Science - 1
Co-authors Mark Parsons
2013 Soederlund T, Yoshino O, Bendinelli C, Enninghorst N, Balogh ZJ, 'Acute repair of traumatic abdominal muscle avulsion from iliac crest: A mesh-free technique using suture anchors', INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 44 1257-1259 (2013) [C3]
DOI 10.1016/j.injury.2013.03.028
2013 Burge K, Balogh Z, 'Striving for excellence', MEDICAL JOURNAL OF AUSTRALIA, 198 C5-C5 (2013) [C3]
2013 Kirkpatrick AW, Roberts DJ, De Waele J, Jaeschke R, Malbrain MLNG, De Keulenaer B, et al., 'Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome', INTENSIVE CARE MEDICINE, 39 1190-1206 (2013) [C1]
DOI 10.1007/s00134-013-2906-z
Citations Scopus - 97Web of Science - 84
2013 Balogh ZJ, McIlroy DJ, Smith DW, Hansbro PM, 'The origin and the role of mitochondrial DNA in postinjury inflammation', Journal of Critical Care, 28 1099-1100 (2013) [C3]
DOI 10.1016/j.jcrc.2013.08.027
Citations Scopus - 2Web of Science - 2
Co-authors Douglas Smith, Philip Hansbro
2013 Sisak K, Manolis M, Hardy BM, Enninghorst N, Balogh ZJ, 'Epidemiology of Acute Transfusions in Major Orthopaedic Trauma', JOURNAL OF ORTHOPAEDIC TRAUMA, 27 413-418 (2013) [C1]
DOI 10.1097/BOT.0b013e31827d7f30
Citations Scopus - 1
2013 Mitchell RJ, Curtis K, Holland AJ, Balogh ZJ, Evans J, Wilson KL, 'Acute costs and predictors of higher treatment costs for major paediatric trauma in New South Wales, Australia', Journal of Paediatrics and Child Health, 49 557-563 (2013) [C1]

Aims To describe the costs of acute trauma admissions for children aged =15 years in trauma centres; to identify predictors of higher treatment costs and quantify differences in a... [more]

Aims To describe the costs of acute trauma admissions for children aged =15 years in trauma centres; to identify predictors of higher treatment costs and quantify differences in actual and state-wide average cost in New South Wales (NSW), Australia. Method Admitted trauma patient data provided by 12 trauma centres was linked with financial data for 2008-2009. Demographic, injury details and injury severity scores (ISS) were obtained from trauma registries. Individual patient costs, Australian Refined Diagnostic Related Groups (AR-DRG) and state-wide average costs were obtained. Actual costs incurred by each hospital were compared with state-wide AR-DRG average costs. Multivariate multiple linear regression identified predictors of cost. Results There were 3493 patients with a total cost of AUD$20.2 million. Falls (AUD$6.7 million) and road trauma (AUD$4.4 million) had the highest total expenditure. The reduction in cost between ISS < 9 compared to ISS 9-12 and ISS > 12 was significant (P < 0.0001). The median cost of injury increased with every additional body region injured (P < 0.0001). For each additional day spent in hospital, there was an increased cost of AUD$1898 and patients admitted to an intensive care unit (ICU) cost AUD$7358 more than patients not admitted to ICU. The total costs incurred by trauma centres were AUD$1.4 million above the NSW peer group average cost estimates. Conclusions The high financial cost of paediatric patient treatment highlights the need to ensure prevention remains a priority in Australia. Hospitals tasked with providing trauma care should be appropriately funded and future funding models should consider trauma severity. © 2013 The Authors. Journal of Paediatrics and Child Health © 2013 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

DOI 10.1111/jpc.12280
Citations Scopus - 1Web of Science - 1
2013 Balogh ZJ, 'Severe trauma in elderly patients', ANZ JOURNAL OF SURGERY, 83 2-3 (2013) [C3]
DOI 10.1111/ans.12034
Citations Web of Science - 1
2013 Balogh ZJ, Fischer A, 'Potential preventive measures against quad bike injuries', ANZ JOURNAL OF SURGERY, 83 198-198 (2013) [C3]
DOI 10.1111/ans.12105
2013 Balogh ZJ, Balogh R, 'Practical Management of Head and Neck Injury. Edited by J. V. Rosenfeld . Sydney: Churchill Livingstone, 2012. Illustrations: > 250 colour and black and whites. Page count: XII and 389 pages. ISBN 9780729539562. Price: $150.00.', ANZ JOURNAL OF SURGERY, 83 393-393 (2013) [C3]
DOI 10.1111/ans.12113
2013 Hunt JJ, Lumsdaine W, Attia J, Balogh ZJ, 'AO type-C distal radius fractures: the influence of computed tomography on surgeon's decision-making', ANZ JOURNAL OF SURGERY, 83 676-678 (2013) [C3]
DOI 10.1111/j.1445-2197.2012.06311.x
Citations Scopus - 1Web of Science - 1
Co-authors John Attia
2013 O'Reilly-Harbidge SC, Balogh ZJ, 'Three-point suture anchor repair of traumatic sternoclavicular joint dislocation', ANZ JOURNAL OF SURGERY, 83 883-886 (2013) [C1]
DOI 10.1111/ans.12403
2013 Hardy BM, Chan S, Martin AB, Brieva J, Gallagher A, Sokolowsky A, Balogh ZJ, 'Temperature change in the helicopter transport of trauma patients', ANZ JOURNAL OF SURGERY, 83 894-895 (2013) [C3]
DOI 10.1111/ans.12138
2013 Sartelli M, Catena F, Ansaloni L, Moore E, Malangoni M, Velmahos G, et al., 'Complicated intra-abdominal infections in a worldwide context: an observational prospective study (CIAOW Study)', WORLD JOURNAL OF EMERGENCY SURGERY, 8 (2013) [C1]
DOI 10.1186/1749-7922-8-1
Citations Scopus - 9Web of Science - 8
2013 Sartelli M, Viale P, Catena F, Ansaloni L, Moore E, Malangoni M, et al., '2013 WSES guidelines for management of intra-abdominal infections', WORLD JOURNAL OF EMERGENCY SURGERY, 8 (2013) [C2]
DOI 10.1186/1749-7922-8-3
Citations Scopus - 25Web of Science - 24
2013 Balogh ZJ, Weber DG, 'Polytrauma and Organ Crosstalk', ICU Management, 13 - (2013) [C3]
2013 Mitchell RJ, Bambach MR, Muscatello D, McKenzie K, Balogh ZJ, 'Can SNOMED CT as implemented in New South Wales, Australia be used for road trauma injury surveillance in emergency departments?', Health Information Management Journal, 42 4-8 (2013) [C1]

The introduction of Systematized Nomenclature of Medicine - Clinical Terms (SNOMED CT) for diagnosis coding in emergency departments (EDs) in New South Wales (NSW) has implication... [more]

The introduction of Systematized Nomenclature of Medicine - Clinical Terms (SNOMED CT) for diagnosis coding in emergency departments (EDs) in New South Wales (NSW) has implications for injury surveillance abilities. This study aimed to assess the consequences of its introduction, as implemented as part of the ED information system in NSW, for identifying road trauma-related injuries in EDs. It involved a retrospective analysis of road trauma-related injuries identified in linked police, ED and mortality records during March 2007 to December 2009. Of all SNOMED CT codes in the principal provisional diagnosis field, between 53.7% and 78.4% referred to the type of injury or symptom experienced by the individual. Of the road users identified by police, 3.2% of vehicle occupants, 6% of motorcyclists, 10.0% of pedal cyclists and 5.2% of pedestrians were identified using SNOMED CT codes in the principal provisional diagnosis field. The introduction of SNOMED CT may provide flexible terminologies for clinicians. However, unless carefully implemented in information systems, its flexibility can lead to mismatches between the intention and actual use of defined data fields. Choices available in SNOMED CT to indicate symptoms, diagnoses, or injury mechanisms need to be controlled and these three concepts need to be retained in separate data fields to ensure a clear distinction between their classifications in the ED.

2013 Williams N, Hardy BM, Tarrant S, Enninghorst N, Attia J, Oldmeadow C, Balogh ZJ, 'Changes in hip fracture incidence, mortality and length of stay over the last decade in an Australian major trauma centre.', Archives of Osteoporosis, 8 (2013) [C1]
DOI 10.1007/s11657-013-0150-3
Citations Scopus - 9
Co-authors John Attia, Christopher Oldmeadow
2013 Enninghorst N, Hardy BM, Sisak K, Lott N, Balogh ZJ, 'Tissue oxygen saturation changes during intramedullary nailing of lower-limb fractures', JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 74 123-127 (2013) [C1]
DOI 10.1097/TA.0b013e3182788e6c
2013 Dewar DC, Tarrant SM, King KL, Balogh ZJ, 'Changes in the epidemiology and prediction of multiple-organ failure after injury', JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 74 774-779 (2013) [C1]
DOI 10.1097/TA.0b013e31827a6e69
Citations Scopus - 11Web of Science - 14
2013 Wong TH, Lumsdaine W, Hardy BM, Balogh ZJ, 'The impact of specialist trauma service on major trauma mortality', JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 74 780-784 (2013) [C1]
DOI 10.1097/TA.0b013e3182826d5f
Citations Scopus - 5Web of Science - 5
2013 Butcher NE, Enninghorst N, Sisak K, Balogh ZJ, 'The definition of polytrauma: Variable interrater versus intrarater agreement-A prospective international study among trauma surgeons', JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 74 884-889 (2013) [C1]
DOI 10.1097/TA.0b013e31827e1bad
Citations Scopus - 3Web of Science - 4
2013 Enninghorst N, McDougall D, Evans JA, Sisak K, Balogh ZJ, 'Population-based epidemiology of femur shaft fractures', Journal of Trauma and Acute Care Surgery, 74 1516-1520 (2013) [C1]

BACKGROUND: Themanagement of patientswith femoral shaft fractures (FSFs) is often a decisionmaking dilemma (damage-control orthopedics vs. early total care), with equivocal eviden... [more]

BACKGROUND: Themanagement of patientswith femoral shaft fractures (FSFs) is often a decisionmaking dilemma (damage-control orthopedics vs. early total care), with equivocal evidence. The comprehensive, population-based epidemiology of patients with FSF is unknown. The purpose of this prospective study was to describe the epidemiology of patientswith FSF, with special focus on patient physiology and timing of surgery. METHODS: A 12-month prospective population-based study was performed on consecutive patients with FSF in an area with 850,000 population including all ages and prehospital deaths. Patient demographics, mechanism, Injury Severity Score (ISS), shock parameters (systolic blood pressure, base deficit and lactate), transfusion requirement, fracture type [Arbeitsgemeinschaft für Osteosynthesefragen/Orthopaedic Trauma Association classification (OA/OTA)], comorbidities, procedures, and outcomes were recorded. Patients hemodynamic status was described as stable, borderline, unstable, and "in extremis." RESULTS: Atotal of 126 patients (21 per 100,000 per year)with 136 femur fractures (62%male; age, 38 [28] years; ISS, 20 [19]; 51%multiple injuries) were identified in the region. Sixty patients (48.4%) sustained a high-energy injury with 19 (31.1%) of these being polytrauma patients (ISS, 28 [12]; systolic blood pressure, 98 [39]; base deficit, 6.5 [5.8]; lactate 4 [2]).Fifteen polytrauma patients (94%) required massive transfusion (12 [12] U of packed red blood cells, 8 [5] fresh frozen plasma, 1 [0.4] platelet, 13 [8] cryoprecipitate). Twenty-one patients (16.7%) died at the prehospital setting (3.5 per 100,000 per year). From the 105 hospital admissions, 68.3% was stable (14.3 per 100,000 per year), 8.7% was borderline (1.8 per 100,000 per year), 4.0% was unstable (0.8 per 100,000 per year) and 2.4%(0.5 per 100,000 per year)was in extremis. Six patients (5.7%) died. The length of stay (LOS) was 18 (15) days, and the intensive care unit LOS was 5 (6) days. Fourty-five patients sustained a low-energy injury that had in 85%of casesmultiple comorbidities. Eight low-energy patients needed 3 (1) transfusions, and none of the patients died. The LOS was 15 (11) days. CONCLUSION: Patients with low-energy FSF have a hospital admission rate similar to the patients with high-energy FSF. Sixty-eight percent of patients with FSF are complicated (open, compromised physiology, multiple injuries, bilateral, elderly with comorbidities, etc.), requiring major resources and highly specialized care. LEVEL OF EVIDENCE: Epidemiology study, level III. Copyright © 2013 Lippincott Williams & Wilkins.

DOI 10.1097/TA.0b013e31828c3dc9
Citations Scopus - 3Web of Science - 3
2012 Butcher NE, Balogh ZJ, 'AIS > 2 in at least two body regions: A potential new anatomical definition of polytrauma', Injury, 43 196-199 (2012) [C1]
Citations Scopus - 15Web of Science - 15
2012 Van Wessem KJP, Mackay PJ, King KL, Balogh ZJ, 'Selective faecal diversion in open pelvic fractures: Reassessment based on recent experience', Injury-International Journal of the Care of the Injured, 43 522-525 (2012) [C3]
2012 Toth L, King KL, McGrath B, Balogh ZJ, 'Efficacy and safety of emergency non-invasive pelvic ring stabilisation', Injury: International Journal of the Care of the Injured, 43 1330-1334 (2012) [C1]
Citations Scopus - 1Web of Science - 1
2012 Easton RM, Bendinelli C, Sisak K, Enninghorst N, Regan D, Evans J, Balogh ZJ, 'Recalled pain scores are not reliable after acute trauma', Injury: International Journal of the Care of the Injured, 43 1029-1032 (2012) [C1]
Citations Scopus - 3Web of Science - 2
2012 Koller H, Balogh ZJ, 'Single training session for first time pelvic C-clamp users: Correct pin placement and frame assembly', Injury: International Journal of the Care of the Injured, 43 436-439 (2012) [C1]
Citations Scopus - 4Web of Science - 4
2012 Yoshino O, Quail AW, Oldmeadow CJ, Balogh ZJ, 'The interpretation of intra-abdominal pressures from animal models: The rabbit to human example', Injury: International Journal of the Care of the Injured, 43 169-173 (2012) [C1]
Citations Scopus - 4Web of Science - 2
Co-authors Tony Quail, Christopher Oldmeadow
2012 Curtis KA, Mitchell RJ, Chong SS, Balogh ZJ, Reed DJ, Clark PT, et al., 'Injury trends and mortality in adult patients with major trauma in New South Wales', Medical Journal of Australia, 197 233-237 (2012) [C1]
Citations Scopus - 16Web of Science - 17
2012 Gruen RL, Brohi K, Schreiber M, Balogh ZJ, Pitt V, Narayan M, Maier RV, 'Haemorrhage control in severely injured patients', Lancet, 380 1099-1108 (2012) [C1]
Citations Scopus - 51Web of Science - 47
2012 Balogh ZJ, Reumann MK, Gruen RL, Mayer-Kuckuk P, Schuetz MA, Harris IA, et al., 'Advances and future directions for management of trauma patients with musculoskeletal injuries', Lancet, 380 1109-1119 (2012) [C1]
Citations Scopus - 18Web of Science - 13
2012 Puchwein P, Enninghorst N, Sisak K, Ortner T, Schildhauer TA, Balogh ZJ, Pichler W, 'Percutaneous fixation of acetabular fractures: Computer-assisted determination of safe zones, angles and lengths for screw insertion', Archives of Orthopaedic and Trauma Surgery, 132 805-811 (2012) [C1]
Citations Scopus - 8Web of Science - 7
2012 Sisak K, Soeyland K, McLeod MG, Jansen M, Enninghorst N, Martin A, Balogh ZJ, 'Massive transfusion in trauma: Blood product ratios should be measured at 6 hours', ANZ Journal of Surgery, 82 161-167 (2012) [C1]
Citations Scopus - 7Web of Science - 7
2012 Easton RM, Sisak K, Balogh ZJ, 'Time to computed tomography scanning for major trauma patients: The Australian reality', ANZ Journal of Surgery, 82 644-647 (2012) [C1]
Citations Scopus - 3Web of Science - 3
2012 Alrahbi R, Easton RM, Bendinelli C, Enninghorst N, Sisak K, Balogh ZJ, 'Intercostal catheter insertion: Are we really doing well?', ANZ Journal of Surgery, 82 392-394 (2012) [C1]
Citations Scopus - 7Web of Science - 7
2012 Bendinelli C, Martin A, Nebauer SD, Balogh ZJ, 'Strangulated intercostal liver herniation subsequent to blunt trauma. First report with review of the world literature', World Journal of Emergency Surgery, 7 23 (2012) [C3]
Citations Scopus - 3Web of Science - 3
2012 Pape HC, Balogh ZJ, 'Physician involvement in the care of multiply injured patients: The role of guidelines and subspecialties', European Journal of Trauma and Emergency Surgery, 38 209-210 (2012) [C3]
2012 Hofman M, Sellei R, Peralta R, Balogh ZJ, Wong TH, Evans JA, et al., 'Trauma systems: Models of prehospital and inhospital care', European Journal of Trauma and Emergency Surgery, 38 253-260 (2012) [C1]
Citations Scopus - 2Web of Science - 3
2012 Livingston D, Gilani R, Balogh Z, Burlew CC, Thorson CM, 'Operating room or angiography suite for hemodynamically unstable pelvic fractures? DISCUSSION', JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 72 371-372 (2012) [C3]
Citations Web of Science - 1
2012 Barquist E, Lucas CE, Cohen MJ, Balogh ZJ, Wohlauer MV, 'Acute kidney injury and posttrauma multiple organ failure: The canary in the coal mine DISCUSSION', JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 72 379-380 (2012) [C3]
Citations Web of Science - 1
2012 Arnold TDW, Balogh ZJ, 'Re: Bland-Altman plot agreement: It is time to stop the stab', Journal of Trauma and Acute Care Surgery, 72 1452-1453 (2012) [C3]
2012 Easton RM, Bendinelli C, Sisak K, Enninghorst N, Balogh ZJ, 'Prehospital nausea and vomiting after trauma: Prevalence, risk factors, and development of a predictive scoring system', Journal of Trauma and Acute Care Surgery, 72 1249-1253 (2012) [C1]
Citations Scopus - 1Web of Science - 1
2011 Balogh ZJ, Pape HC, 'The challenges and advances of polytrauma care in 2012', European Journal of Trauma and Emergency Surgery, 37 537-538 (2011) [C3]
2011 Sisak K, Dewar D, Butcher N, King K, Evans J, Miller M, et al., 'The treatment of traumatic shock: Recent advances and unresolved questions', European Journal of Trauma and Emergency Surgery, 37 567-575 (2011) [C1]
Citations Scopus - 1Web of Science - 1
2011 Enninghorst N, Peralta R, Yoshino O, Pfeifer R, Pape HC, Hardy BM, et al., 'Physiological assessment of the polytrauma patient: initial and secondary surgeries', European Journal of Trauma and Emergency Surgery, 37 559-566 (2011) [C1]
Citations Scopus - 1Web of Science - 1
2011 Dewar D, Balogh ZJ, 'The epidemiology of multiple-organ failure: A definition controversy', Acta Anaesthesiologica Scandinavica, 55 248-249 (2011) [C3]
DOI 10.1111/j.1399-6576.2010.02352.x
Citations Scopus - 3Web of Science - 3
2011 Balogh ZJ, Leppaniemi A, 'Patient populations at risk for intra-abdominal hypertension and abdominal compartment syndrome', American Surgeon, 77 S12-S16 (2011) [C1]
Citations Scopus - 5Web of Science - 3
2011 Balogh ZJ, Malbrain M, 'Resuscitation in intra-abdominal hypertension and abdominal compartment syndrome', American Surgeon, 77 S31-S33 (2011) [C1]
Citations Scopus - 7Web of Science - 3
2011 Balogh ZJ, Martin A, Van Wessem KP, King KL, Mackay P, Havill K, 'Mission to eliminate postinjury abdominal compartment syndrome', Archives of Surgery, 146 938-943 (2011) [C1]
DOI 10.1001/archsurg.2011.73
Citations Scopus - 20Web of Science - 13
2011 Harrigan PW, Balogh ZJ, 'Quality trauma research and major trauma registries', Injury, 42 38-39 (2011) [C3]
DOI 10.1016/j.injury.2010.11.034
Citations Scopus - 1Web of Science - 1
2011 Cohen MJ, Lottenberg L, Cryer HG, Balogh Z, Moore EE, Kaplan LJ, Cotton BA, 'Rapid Thrombelastography Delivers Real-Time Results That Predict Transfusion Within 1 Hour of Admission DISCUSSION', JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 71 414-417 (2011) [C3]
Citations Web of Science - 24
2011 Arnold TDW, Miller MK, Van Wessem KP, Evans JA, Balogh ZJ, 'Base deficit from the first peripheral venous sample: A surrogate for arterial base deficit in the trauma bay', Journal of Trauma - Injury, Infection and Critical Care, 71 793-797 (2011) [C1]
Citations Scopus - 9Web of Science - 8
2011 Balogh ZJ, 'Editorial comment', Journal of Trauma - Injury, Infection and Critical Care, 71 590 (2011) [C3]
DOI 10.1097/TA.0b013e318224cd62
2011 Enninghorst N, McDougall D, Hunt JJ, Balogh ZJ, 'Open tibia fractures: Timely debridement leaves injury severity as the only determinant of poor outcome', Journal of Trauma-Injury Infection and Critical Care, 70 352-356 (2011) [C1]
DOI 10.1097/ta.0b013e31820b4285
Citations Scopus - 9Web of Science - 7
2011 Bhandari M, Guyatt G, Jeray K, Balogh ZJ, King KL, Flow Investigators, 'Fluid lavage of open wounds (FLOW): A multicenter, blinded, factorial pilot trial comparing alternative irrigating solutions and pressures in patients with open fractures', Journal of Trauma-Injury Infection and Critical Care, 71 596-606 (2011) [C1]
DOI 10.1097/ta.0b013e3181f6f2e8
Citations Scopus - 13Web of Science - 9
2011 Balogh ZJ, 'Traumatic shock resuscitation with a 1:1 plasma to packed red blood cell ratio: Is it to please ourselves or the injured?', Critical Care Medicine, 39 1597-1598 (2011) [C3]
DOI 10.1097/ccm.0b013e3182148a6a
2011 Crash-2 Collaborators, Balogh ZJ, 'The importance of early treatment with tranexamic acid in bleeding trauma patients: An exploratory analysis of the CRASH-2 randomised controlled trial', The Lancet, 377 1096.e2-1101.e2 (2011) [C1]
DOI 10.1016/S0140-6736(11)60278-X
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2011 Nicholas B, Toth L, Van Wessem K, Evans J, Enninghorst N, Balogh ZJ, 'Borderline femur fracture patients: Early total care or damage control orthopaedics?', ANZ Journal of Surgery, 81 148-153 (2011) [C1]
DOI 10.1111/j.1445-2197.2010.05582.x
Citations Scopus - 7Web of Science - 6
2011 Fick AEA, Raychaudhuri P, Bear J, Roy G, Balogh ZJ, Kumar R, 'Factors predicting the need for splenectomy in children with blunt splenic trauma', ANZ Journal of Surgery, 81 717-719 (2011) [C1]
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2011 Balogh ZJ, 'Solutions for complex upper extremity trauma', ANZ Journal of Surgery, 81 567-568 (2011) [C3]
2011 Dewar D, Butcher NE, King KL, Balogh ZJ, 'Post injury multiple organ failure', Trauma, 13 81-91 (2011) [C1]
DOI 10.1177/1460408610386657
Citations Scopus - 3
2010 De Waele JJ, Cheatham ML, Balogh ZJ, Bjorck M, D'Amours S, De Keulenaer B, et al., 'Intra-abdominal pressure measurement using a U-Tube technique: Caveat emptor', Annals of Surgery, 252 890-891 (2010) [C3]
DOI 10.1097/SLA.0b013e3181fded35
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2010 Balogh ZJ, Martin AB, 'Prospective cohorts and risk adjusted outcomes for trauma', Injury-International Journal of the Care of the Injured, 41S 24-26 (2010) [C2]
DOI 10.1016/j.injury.2010.03.034
Citations Scopus - 2Web of Science - 2
2010 Balogh ZJ, Wiles CE, Mullins R, Bosse MJ, 'Skeletal Traction Versus External Fixation in the Initial Temporization of Femoral Shaft Fractures in Severely Injured Patients DISCUSSION', JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 68 638-639 (2010) [C3]
2010 Hoyt DB, Balogh ZJ, Kozar RA, Cook A, 'Acute Definitive Internal Fixation of Pelvic Ring Fractures in Polytrauma Patients: A Feasible Option DISCUSSION', JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 68 939-941 (2010) [C3]
2010 Coimbra R, Billiar TR, Balogh Z, Poggetti RS, Huynh TT, 'Reducing Leukocyte Trafficking Preserves Hepatic Function After Sepsis DISCUSSION', JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 69 366-367 (2010) [C3]
2010 Balogh ZJ, 'Discussion', Journal of Trauma, 68 638-640 (2010) [C3]
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2010 Balogh ZJ, 'Editorial comment', Journal of Trauma - Injury, Infection and Critical Care, 68 638-640 (2010) [C3]
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2010 Enninghorst N, Toth L, King KL, McDougall D, Mackenzie S, Balogh ZJ, 'Acute definitive internal fixation of pelvic ring fractures in polytrauma patients: A feasible option', Journal of Trauma - Injury, Infection and Critical Care, 68 935-939 (2010) [C1]
DOI 10.1097/TA.0b013e3181d27b48
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2010 Toth L, Balogh ZJ, 'Isolated unilateral sacroiliac dislocation without anterior pelvic ring disruption', Journal of Trauma-Injury Infection and Critical Care, 68 E83-E86 (2010) [C3]
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2010 Balogh ZJ, 'Skeletal traction versus external fixation in the initial temporization of femoral shaft fractures in severely injured patients. Editorial Comment', Journal of Trauma-Injury Infection and Critical Care, 68 639-640 (2010) [C3]
2010 Balogh ZJ, Butcher N, 'Compartment syndromes from head to toe', Critical Care Medicine, 38 S445-S451 (2010) [C1]
DOI 10.1097/CCM.0b013e3181ec5d09
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2010 Shakur H, Roberts I, Bautista R, Caballero J, Coats T, Dewan Y, et al., 'Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial', LANCET, 376 23-32 (2010) [C1]
DOI 10.1016/S0140-6736(10)60835-5
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2010 Balogh ZJ, Evans JA, 'Epidemiology of trauma deaths: Volume, methodology, and comparability-Reply to Letter', World Journal of Surgery, 34 1722-1723 (2010) [C3]
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2010 Balogh ZJ, Evans JA, 'Epidemiology of trauma deaths: Location, location, location! Reply', World Journal of Surgery, 34 1722-1723 (2010) [C3]
2010 Evans JA, Van Wessem KJP, McDougall D, Lee KA, Lyons TJ, Balogh ZJ, 'Epidemiology of traumatic deaths: Comprehensive population-based assessment', World Journal of Surgery, 34 158-163 (2010) [C1]
DOI 10.1007/s00268-009-0266-1
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2010 Balogh ZJ, 'Traumatology in Australia: Provision of clinical care and trauma system development', ANZ Journal of Surgery, 80 119-121 (2010) [C3]
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Citations Scopus - 5Web of Science - 4
2009 De Waele JJ, Cheatham ML, Malbrain MLNG, Kirkpatrick AW, Sugrue M, Balogh ZJ, et al., 'Recommendations for research from the international conference of experts on intra-abdominal hypertension and abdominal compartment syndrome', Acta Clinica Belgica, 64 203-209 (2009) [C1]
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2009 Cheatham M, De Waele J, Kirkpatrick A, Sugrue M, Malbrain MLN, Ivatury RR, et al., 'Criteria for a diagnosis of abdominal compartment syndrome', Canadian Journal of Surgery, 52 315-316 (2009) [C3]
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2009 Dewar D, Moore FA, Moore EE, Balogh ZJ, 'Postinjury multiple organ failure', Injury, 40 912-918 (2009) [C1]
DOI 10.1016/j.injury.2009.05.024
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2009 Tan SLE, Balogh ZJ, 'Indications and limitations of locked plating', Injury, 40 683-691 (2009) [C1]
DOI 10.1016/j.injury.2009.01.003
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2009 Butcher N, Balogh ZJ, 'The definition of polytrauma: The need for international consensus', Injury - International Journal of the Care of the Injured, 40S4 S12-S22 (2009) [C1]
DOI 10.1016/j.injury.2009.10.032
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2009 Sekine K, Holcomb JB, Moore FA, Duchesne J, Schreiber M, Hawkins ML, et al., 'Predefined Massive Transfusion Protocols are Associated With a Reduction in Organ Failure and Postinjury Complications DISCUSSION', JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 66 48-49 (2009) [C3]
Citations Web of Science - 19
2009 Croce MA, Livingston DH, Duane TM, Asensio JA, McQuay N, Balogh ZJ, Dabbs DN, 'Major Hepatic Necrosis: A Common Complication After Angioembolization for Treatment of High-Grade Liver Injuries Discussion', JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 66 627-629 (2009) [C3]
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2009 Sekine K, Holcomb JB, Moore FA, Duchesne J, Schreiber M, Hawkins ML, et al., 'Discussion', Journal of Trauma - Injury, Infection and Critical Care, 66 48-49 (2009) [C3]
DOI 10.1097/TA.0b013e31819313bb
2009 Croce MA, Livingston DH, Duane TM, Asensio JA, McQuay Jr N, Balogh ZJ, Dabbs DN, 'Discussion', Journal of Trauma - Injury, Infection and Critical Care, 66 627-629 (2009) [C3]
DOI 10.1097/TA.0b013e31819919f2
2009 Balogh ZJ, Leppaniemi A, 'The neglected (abdominal) compartment: What is new at the beginning of the 21st century?', World Journal of Surgery, 33 1109 (2009) [C3]
DOI 10.1007/s00268-009-0001-y
Citations Scopus - 5Web of Science - 3
2009 Balogh ZJ, Van Wessem K, Yoshino O, Moore FA, 'Postinjury abdominal compartment syndrome: Are we winning the battle?', World Journal of Surgery, 33 1134-1141 (2009) [C1]
DOI 10.1007/s00268-009-0002-x
Citations Scopus - 27Web of Science - 22
2009 Dewar D, Mackay P, Balogh ZJ, 'Epidemiology of post-injury multiple organ failure in an Australian trauma system', ANZ Journal of Surgery, 79 431-436 (2009) [C1]
DOI 10.1111/j.1445-2197.2009.04968.x
Citations Scopus - 7Web of Science - 6
2008 Lameire N, Balogh Z, Lumb P, 'Editorial introductions', Current Opinion in Critical Care, 14 (2008) [C3]
2008 Balogh ZJ, 'Section editor', Current Opinion in Critical Care, 14 (2008) [C2]
2008 Bendinelli C, Balogh ZJ, 'Postinjury thromboprophylaxis', Current Opinion in Critical Care, 14 673-678 (2008) [C1]
DOI 10.1097/mcc.0b013e3283196538
Citations Scopus - 7Web of Science - 4
2008 Sugrue M, Balogh ZJ, Lynch J, Bardsley J, Sisson G, Weigelt J, 'Guidelines for the management of haemodynamically stable patients with stab wounds [Letter]', ANZ Journal of Surgery, 78 106-107 (2008) [C3]
DOI 10.1111/j.1445-2197.2007.04380.x
2008 Sugrue M, Balogh ZJ, Lynch J, Bardsley J, Sisson G, Weigelt J, 'Re: Guidelines for the management of haemodynamically stable patients with stab wounds to the anterior abdomen [Letter]', ANZ Journal of Surgery, 78 111 (2008) [C3]
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2008 Balogh ZJ, 'Australian trauma care: Time for change', ANZ Journal of Surgery, 78 935-936 (2008) [C3]
Citations Scopus - 3Web of Science - 3
2008 Balogh ZJ, Bendinelli C, Pollitt T, Kozar RA, Moore FA, 'Postinjury primary abdominal compartment syndrome', European Journal of Trauma and Emergency Surgery, 34 369-377 (2008) [C1]
DOI 10.1007/s00068-008-8106-9
Citations Scopus - 2Web of Science - 2
2008 Cameron P, Phillips L, Balogh Z, Joseph A, Pearce A, Parr M, Jankelowitz G, 'The use of recombinant activated factor VII in trauma patients: Experience from the Australian and New Zealand haemostasis registry (vol 38, pg 1030, 2007)', INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 39 138-139 (2008) [C3]
DOI 10.1016/j.injury.2007.09.006
Citations Web of Science - 1
2008 Collins JP, Civil ID, Sugrue M, Balogh ZJ, Chehade MJ, 'Surgical education and training in Australia and New Zealand', World Journal of Surgery, 32 2138-2144 (2008) [C1]
DOI 10.1007/s00268-008-9680-z
Citations Scopus - 17Web of Science - 14
2008 Verbeek D, Sugrue M, Balogh ZJ, Cass D, Civil I, Harris I, et al., 'Acute management of hemodynamically unstable pelvic trauma patients: Time for a change? Multicenter review of recent practice', World Journal of Surgery, 32 1874-1882 (2008) [C1]
DOI 10.1007/s00268-008-9591-z
Citations Scopus - 48Web of Science - 38
2007 Cheatham ML, Malbrain M, Kirkpatrick A, Sugrue M, Parr M, Dewaele J, et al., 'Results from the International Conference of Experts on Intra-Abdominal Hypertension and Abdominal Compartment Syndrome. II. Recommendations', Intensive Care Medicine, 33 951-962 (2007) [C1]
DOI 10.1007/s00134-007-0592-4
Citations Scopus - 418Web of Science - 373
2007 Moore F, McKinley B, Balogh Z, 'The problem: Coagulopathy of posttraumatic massive transfusion (PMT)', INFLAMMATION RESEARCH, 56 S187-S188 (2007)
2007 Bodnar Z, Sipka S, Szentkereszty Z, Hajdu Z, Balogh Z, 'The gold standard technique for intra-abdominal pressure monitoring in septic patients: Continuous intra-abdominal pressure monitoring (CIAPM)', INFLAMMATION RESEARCH, 56 S213-S214 (2007)
2007 Balogh Z, Bodnar Z, Moore F, 'Abdominal compartment syndrome complicating infection', INFLAMMATION RESEARCH, 56 S240-S240 (2007)
2007 Sugrue M, Balogh ZJ, Lynch J, Bardsley J, Sisson G, Weigelt J, 'Guidelines for the management of haemodynamically stable patients with stab wounds to the anterior abdomen', ANZ Journal of Surgery, 77 614-620 (2007) [C1]
DOI 10.1111/j.1445-2197.2007.04173.x
Citations Scopus - 14Web of Science - 14
2007 Balogh Z, 'Continuous intra-abdominal pressure monitoring', ACTA CLINICA BELGICA, 62 234-234 (2007)
2007 Mackay P, van Wessem K, Balogh Z, 'Post-injury abdominal compartment syndrome: Is it still a problem?', ACTA CLINICA BELGICA, 62 293-293 (2007)
2007 Balogh ZJ, De Waele JJ, Malbrain M, 'Continuous intra-abdominal pressure monitoring', Acta Clinica Belgica, 62 26-32 (2007) [C1]
Citations Scopus - 40Web of Science - 22
2007 Cameron P, Phillips L, Balogh ZJ, Joseph A, Pearce A, Parr M, Jankelowitz G, 'The use of recombinant activated factor VII in trauma patients: Experience from the Australian and New Zealand haemostasis registry', Injury, 38 1030-1038 (2007) [C1]
DOI 10.1016/j.injury.2007.05.003
Citations Scopus - 18Web of Science - 18
2007 Balogh ZJ, Moore FA, Moore EE, Biffl WL, 'Secondary abdominal compartment syndrome: A potential threat for all trauma clinicians', Injury - International Journal of the Care of the Injured, 38 272-279 (2007) [C1]
DOI 10.1016/j.injury.2006.02.026
Citations Scopus - 34Web of Science - 26
2007 Peitzman AB, Balogh Z, Hauser C, 'The epidemiology of pelvic ring fractures: A population-based study - Discussion', JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 63 1072-1073 (2007)
Citations Web of Science - 2
2007 Balogh ZJ, Evans JA, Seah PW, King KL, 'Supraclavicular cyanosis: Clinical sign of acute blunt traumatic pericardial tamponade', Journal of Trauma - Injury, Infection and Critical Care, 63 245 (2007) [C3]
2007 Balogh Z, King KL, Mackay P, McDougall D, Mackenzie S, Evans JA, et al., 'The epidemiology of pelvic ring fractures: A population-based study', Journal of Trauma-Injury Infection and Critical Care, 63 1066-1073 (2007) [C1]
DOI 10.1097/TA.0b013e3181589fa4
Citations Scopus - 46Web of Science - 36
2007 Balogh ZJ, De Waele JJ, Kirkpatrick A, Cheatham M, D'Amours S, Malbrain M, 'Intra-abdominal pressure measurement and abdominal compartment syndrome: The opinion of the World Society of the Abdominal Compartment Syndrome (Letter)', Critical Care Medicine, 35 677-678 (2007) [C3]
Citations Scopus - 3Web of Science - 2
2006 Malbrain MLNG, Cheatham ML, Kirkpatrick A, Sugrue M, Parr M, De Waele J, et al., 'Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome. I. Definitions', Intensive Care Medicine, 32 1722-1732 (2006) [C1]
DOI 10.1007/s00134-006-0349-5
Citations Scopus - 560Web of Science - 519
2006 Balogh Z, Kirkpatrick AW, Ball CG, Zygun D, 'The secondary abdominal compartment syndrome: Iatrogenic or unavoidable?', JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 203 406-407 (2006)
DOI 10.1016/j.jamcollsurg.2006.06.007
Citations Scopus - 3
2006 Kirkpatrick AW, Balogh ZJ, Ball CG, Ahmed N, Chun R, McBeth P, et al., 'The secondary abdominal compartment syndrome: Iatrogenic or unavoidable?', Journal of the American College of Surgeons, 202 668-679 (2006) [C1]
DOI 10.1016/j.jamcollsurg.2005.11.020
Citations Scopus - 83Web of Science - 72
2006 Ollerton JE, Sugrue M, Balogh Z, D'Amours SK, Giles A, Wyllie P, 'Prospective study to evaluate the influence of FAST on trauma patient management', JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 60 785-791 (2006)
DOI 10.1097/01.ta.0000214583.21492.e8
Citations Scopus - 53Web of Science - 40
2005 Balogh Z, Moore FA, 'Intra-abdominal hypertension: Not just a surgical critical care curiosity', CRITICAL CARE MEDICINE, 33 447-449 (2005)
DOI 10.1097/01.CCM.0000153411.35214.91
Citations Scopus - 8Web of Science - 8
2005 Balogh Z, Caldwell E, Heetveld M, D'Amours S, Schlaphoff G, Harris I, Sugrue M, 'Institutional practice guidelines on management of pelvic fracture-related hemodynamic instability: Do they make a difference?', JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 58 778-782 (2005)
DOI 10.1097/01.TA.0000158251.40760.B2
Citations Scopus - 77Web of Science - 69
2004 Cribari C, Balogh Z, Moore F, Kuhls D, 'Continuous intra-abdominal pressure measurement technique - Discussion', AMERICAN JOURNAL OF SURGERY, 188 683-684 (2004)
2004 Balogh Z, Moore FA, McKinley BA, 'Supranormal trauma resuscitation and abdominal compartment syndrome - In reply', ARCHIVES OF SURGERY, 139 226-227 (2004)
DOI 10.1001/archsurg.139.2.226
Citations Web of Science - 2
2004 Heetveld MJ, Harris I, Schlaphoff G, Balogh Z, D'Amours SK, Sugrue M, 'Hemodynamically unstable pelvic fractures: Recent care and new guidelines', WORLD JOURNAL OF SURGERY, 28 904-909 (2004)
DOI 10.1007/s00268-004-7357-9
Citations Scopus - 49Web of Science - 45
2004 Balogh Z, Moore FA, 'Recent advances in the characterisation of post-injury abdominal compartment syndrome', International Journal of Intensive Care, 11 30-42 (2004)

Abdominal compartment syndrome (ACS) is defined as intra-abdominal pressure (IAP) higher than 25 mmHg with organ dysfunction (cardiac, respiratory, renal) if the organ dysfunction... [more]

Abdominal compartment syndrome (ACS) is defined as intra-abdominal pressure (IAP) higher than 25 mmHg with organ dysfunction (cardiac, respiratory, renal) if the organ dysfunction improves after abdominal decompression. ACS is the imbalance between abdominal volume and abdominal content where the abdominal volume is defined by the least tensile component of the abdominal compartment (i.e. the fascia). Increasing abdominal content or decreasing volume causes ACS, which impairs abdominal organ perfusion, as in other well recognised 'compartment' conditions of increased intra-cranial pressure, pericardial tamponade, tension pneumothorax or extremity compartment syndromes.

2004 Sugrue M, Balogh Z, Malbrain M, 'Intra-abdominal hypertension and renal failure', ANZ JOURNAL OF SURGERY, 74 78-78 (2004)
DOI 10.1046/j.1445-1433.2003.02896.x
Citations Scopus - 13Web of Science - 11
2003 Balogh ZJ, 'Supra-normal trauma resuscitation causes more cases of abdominal compartment syndrome', Archives of Surgery, 637-642 (2003) [C1]
Citations Scopus - 284Web of Science - 233
2003 Balogh Z, Voros E, Suveges G, Simonka JA, 'Stent graft treatment of an external iliac artery injury associated with pelvic fracture - A case report', JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 85A 919-922 (2003)
Citations Scopus - 1Web of Science - 1
2003 Reilly P, Balogh Z, Shackford SR, Wang D, 'Both primary and secondary abdominal compartment syndrome can be predicted early and are harbingers of multiple organ failure - Discussion', JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 54 859-861 (2003)
Citations Web of Science - 30
2003 Miller CC, Balogh Z, McKinley BA, Moore FA, 'Letter to the Editor - The Author's Reply', JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 55 1004-1005 (2003)
2003 Balogh ZJ, Varga E, Tomka J, Suveges G, Toth L, Simonka JA, 'The new injury severity score is a better predictor of extended hospitalization and intensive care unit admission than the injury severity score in patients with multiple orthopaedic injuries', JOURNAL OF ORTHOPAEDIC TRAUMA, 17 508-512 (2003)
DOI 10.1097/00005131-200308000-00006
Citations Scopus - 29Web of Science - 24
2003 Balogh Z, McKinley BA, Cox CS, Allen SJ, Cocanour CS, Kozar RA, et al., 'Abdominal compartment syndrome: The cause or effect of postinjury multiple organ failure', SHOCK, 20 483-492 (2003)
DOI 10.1097/01.shk.0000093346.68755.43
Citations Scopus - 117Web of Science - 105
2003 Bowling WM, Miller CC, Balogh Z, McKinley BA, Moore FA, 'Letter to the editor [1] (multiple letters)', Journal of Trauma - Injury, Infection and Critical Care, 55 1004-1005 (2003)
DOI 10.1097/01.TA.0000094212.36512.78
2002 Balogh Z, Wolfard A, Szalay L, Orosz E, Simonka JA, Boros M, 'Dalteparin sodium treatment during resuscitation inhibits hemorrhagic shock-induced leukocyte rolling and adhesion in the mesenteric microcirculation', JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 52 1062-1069 (2002)
DOI 10.1097/00005373-200206000-00007
Citations Scopus - 8Web of Science - 7
2002 Burch J, Balogh Z, Smith S, 'Secondary abdominal compartment syndrome is an elusive early complication of traumatic shock resuscitation - Discussion', AMERICAN JOURNAL OF SURGERY, 184 543-544 (2002)
Citations Web of Science - 12
2000 Balogh Z, Offner PJ, Moore EE, Biffl WL, 'NISS predicts postinjury multiple organ failure better than the ISS', JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 48 624-627 (2000)
DOI 10.1097/00005373-200004000-00007
Citations Scopus - 57Web of Science - 42
2000 Osler TM, West A, Hauser CJ, Lewis FR, Balogh Z, 'NISS predicts postinjury multiple organ failure better than the ISS - Discussion', JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 48 627-628 (2000)
Citations Web of Science - 5
1999 Wolfard A, Kaszaki J, Szabo C, Balogh Z, Nagy S, Boros M, 'Effects of selective nitric oxide synthase inhibition in hyperdynamic endotoxemia in dogs', EUROPEAN SURGICAL RESEARCH, 31 314-323 (1999)
DOI 10.1159/000008708
Citations Scopus - 8Web of Science - 8
1997 Wolfárd A, Kaszaki J, Szabó C, Balogh Z, Nagy S, 'Effects of nitric oxide synthase inhibition on the hemodynamic changes in hyperdynamic endotoxemia.', Acta chirurgica Hungarica, 36 393-394 (1997)

In this study we compared the circulatory effects of the arginine analogue non-specific nitric oxide synthase (NOS) inhibitor N omega-nitro-L-arginine (NNA), and the specific indu... [more]

In this study we compared the circulatory effects of the arginine analogue non-specific nitric oxide synthase (NOS) inhibitor N omega-nitro-L-arginine (NNA), and the specific inducible NOS (iNOS) inhibitor S-methylisothiourea (SMT) and S-(2-aminoethyl)-isothiourea (AEST) in a hyperdynamic endotoxemic dog model. Mean arterial pressure (MAP), cardiac output (CO), and myocardial contractility (MC) were measured. A hyperdynamic circulatory response was elicited with a 2-h infusion of a total dose of 5.3 micrograms/kg E. coli endotoxin (ETX). NOS inhibitory treatment (2 mg/kg) was administrated from the 45th min of endotoxemia. ETX induced a hyperdynamic circulatory response, and a significant myocardial depression. NNA induced a prolonged, SMT a transient increase in MC, both drugs elevated MAP, but decreased CO. AEST significantly prolonged the elevation in CO, but did not affect MAP. Selective inhibition of the iNOS may be a beneficial in sepsis.

Citations Scopus - 1
Show 170 more journal articles

Conference (39 outputs)

Year Citation Altmetrics Link
2015 McIlroy DJ, Bigland M, White AE, Hardy BM, Lott N, Smith DW, Balogh ZJ, 'Cell necrosis-independent sustained mitochondrial and nuclear DNA release following trauma surgery', Journal of Trauma and Acute Care Surgery (2015)

Background: Mitochondrial DNA (mtDNA), a potent proinflammatory damage-associated molecular pattern, is released in large titers following trauma. The effect of trauma surgery on ... [more]

Background: Mitochondrial DNA (mtDNA), a potent proinflammatory damage-associated molecular pattern, is released in large titers following trauma. The effect of trauma surgery on mtDNA concentration is unknown. We hypothesized that mtDNA and nuclear DNA (nDNA) levels would increase proportionately with the magnitude of surgery and both would then decrease rapidly. Methods: In this prospective pilot, plasma was sampled from 35 trauma patients requiring orthopedic surgical intervention at six perioperative time points. Healthy control subjects (n = 20)were sampled.DNAwas extracted, and the mtDNA and nDNAwere assessed using quantitative polymerase chain reaction. Markers of cell necrosis were also assayed (creatine kinase, lactate dehydrogenase, and aspartate aminotransferase). Results: The free plasma mtDNA and nDNA levels (ng/mL) were increased in trauma patients compared with healthy controls at all time points (mtDNA: preoperative period, 108 [46-284]; postoperative period, 96 [29-200]; 7 hours postoperatively, 88 [43-178]; 24 hours, 79 [36-172]; 3 days, 136 [65-263]; 5 days, 166 [101-434] [healthy controls, 11 (5-19)]) (nDNA: preoperative period, 52 [25-130]; postoperative period, 100 [35-208]; 7 hours postoperatively, 75 [36-139]; 24 hours postoperatively, 85 [47-133]; 3 days, 79 [48-117]; 5 days, 99 [41-154] [healthy controls, 29 (16-54)]). Elevated DNA levels did not correlate with markers of cellular necrosis. mtDNA was significantly elevated compared with nDNA at preoperative period (p = 0.003), 3 days (p = 0.003), and 5 days (p = 0.0014). Preoperative mtDNA levelswere greater with shorter time from injury to surgery (p = 0.0085). Postoperative mtDNA level negatively correlated with intraoperative crystalloid infusion (p = 0.0017). Major pelvic surgery (vs. minor) was associated with greater mtDNA release 5 days postoperatively (p G 0.05). Conclusion: This pilot of heterogeneous orthopedic trauma patients showed that the release of mtDNA and nDNA is sustained for 5 days following orthopedic trauma surgery. Postoperative, circulating DNA is not associated with markers of tissue necrosis but is associated with surgical invasiveness and is inversely related to intraoperative fluid administration. Sustained elevation of mtDNA levels could be of inflammatory origin and may contribute to postinjury dysfunctional inflammation. Level of Evidence: Prospective study, level III.

DOI 10.1097/TA.0000000000000519
Citations Scopus - 2
2015 Duchesne JC, Kaplan LJ, Balogh ZJ, Malbrain MLNG, 'Role of permissive hypotension, hypertonic resuscitation and the global increased permeability syndrome in patients with severe haemorrhage: Adjuncts to damage control resuscitation to prevent intra-abdominal hypertension', Anaesthesiology Intensive Therapy (2015)

Secondary intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are closely related to fluid resuscitation. IAH causes major deterioration of the cardiac fun... [more]

Secondary intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are closely related to fluid resuscitation. IAH causes major deterioration of the cardiac function by affecting preload, contractility and afterload. The aim of this review is to discuss the different interactions between IAH, ACS and resuscitation, and to explore a new hypothesis with regard to damage control resuscitation, permissive hypotension and global increased permeability syndrome. The recognition of the association between the development of ACS and resuscitation urged the need for new approach in traumatic shock management. Over a decade after wide spread application of damage control surgery damage control resuscitation was developed. DCR differs from previous resuscitation approaches by attempting an earlier and more aggressive correction of coagulopathy, as well as metabolic derangements like acidosis and hypothermia, often referred to as the 'deadly triad' or the 'bloody vicious cycle'. Permissive hypotension involves keeping the blood pressure low enough to avoid exacerbating uncontrolled haemorrhage while maintaining perfusion to vital end organs. The potential detrimental mechanisms of early, aggressive crystalloid resuscitation have been described. Limitation of fluid intake by using colloids, hypertonic saline (HTS) or hyperoncotic albumin solutions have been associated with favourable effects. HTS allows not only for rapid restoration of circulating intravascular volume with less administered fluid, but also attenuates post-injury oedema at the microcirculatory level and may improve microvascular perfusion. Capillary leak represents the maladaptive, often excessive, and undesirable loss of fluid and electrolytes with or without protein into the interstitium that generates oedema. The global increased permeability syndrome (GIPS) has been articulated in patients with persistent systemic inflammation failing to curtail transcapillary albumin leakage and resulting in increasingly positive net fluid balances. GIPS may represent a third hit after the initial insult and the ischaemia reperfusion injury. Novel markers like the capillary leak index, extravascular lung water and pulmonary permeability index may help the clinician in guiding appropriate fluid management. Capillary leak is an inflammatory condition with diverse triggers that results from a common pathway that includes ischaemia-reperfusion, toxic oxygen metabolite generation, cell wall and enzyme injury leading to a loss of capillary endothelial barrier function. Fluid overload should be avoided in this setting.

DOI 10.5603/AIT.a2014.0052
2014 Duchesne JC, Kaplan LJ, Balogh ZJ, Malbrain MLNG, 'Role of permissive hypotension, hypertonic resuscitation and the global increased permeability syndrome in patients with severe haemorrhage: Adjuncts to damage control resuscitation to prevent intra-abdominal hypertension', Anaesthesiology Intensive Therapy (2014)

Secondary intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are closely related to fluid resuscitation. IAH causes major deterioration of the cardiac fun... [more]

Secondary intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are closely related to fluid resuscitation. IAH causes major deterioration of the cardiac function by affecting preload, contractility and afterload. The aim of this review is to discuss the different interactions between IAH, ACS and resuscitation, and to explore a new hypothesis with regard to damage control resuscitation, permissive hypotension and global increased permeability syndrome. The recognition of the association between the development of ACS and resuscitation urged the need for new approach in traumatic shock management. Over a decade after wide spread application of damage control surgery damage control resuscitation was developed. DCR differs from previous resuscitation approaches by attempting an earlier and more aggressive correction of coagulopathy, as well as metabolic derangements like acidosis and hypothermia, often referred to as the 'deadly triad' or the 'bloody vicious cycle'. Permissive hypotension involves keeping the blood pressure low enough to avoid exacerbating uncontrolled haemorrhage while maintaining perfusion to vital end organs. The potential detrimental mechanisms of early, aggressive crystalloid resuscitation have been described. Limitation of fluid intake by using colloids, hypertonic saline (HTS) or hyperoncotic albumin solutions have been associated with favourable effects. HTS allows not only for rapid restoration of circulating intravascular volume with less administered fluid, but also attenuates post-injury oedema at the microcirculatory level and may improve microvascular perfusion. Capillary leak represents the maladaptive, often excessive, and undesirable loss of fluid and electrolytes with or without protein into the interstitium that generates oedema. The global increased permeability syndrome (GIPS) has been articulated in patients with persistent systemic inflammation failing to curtail transcapillary albumin leakage and resulting in increasingly positive net fluid balances. GIPS may represent a third hit after the initial insult and the ischaemia reperfusion injury. Novel markers like the capillary leak index, extravascular lung water and pulmonary permeability index may help the clinician in guiding appropriate fluid management. Capillary leak is an inflammatory condition with diverse triggers that results from a common pathway that includes ischaemia-reperfusion, toxic oxygen metabolite generation, cell wall and enzyme injury leading to a loss of capillary endothelial barrier function. Fluid overload should be avoided in this setting.

DOI 10.5603/AIT.a2014.0052
2012 Hardy BM, Yoshino O, Quail AW, Balogh ZJ, 'Influence of the timing of internal fixation of femur fractures during shock resuscitation on remote organ damage', ANZ Journal of Surgery, Kuala Lumpur, Malaysia (2012) [E3]
Co-authors Tony Quail
2011 Koller H, Uranues S, Balogh ZJ, 'Single training session for first time pelvic C-clamp users: What to expect?', World Journal of Surgery, Yokohama, Japan (2011) [E3]
2011 Yoshino O, Matthys R, Balogh ZJ, 'Blunt polytrauma model with femur fracture', World Journal of Surgery, Yokohama, Japan (2011) [E3]
2011 Sisak K, Balogh ZJ, Bendinelli C, Enninghorst N, 'Acute transfusion practice during trauma resuscitation: Who, when and why?', ANZ Journal of Surgery, Adelaide, SA (2011) [E3]
2011 Enninghorst N, McDougall D, Sisak K, Balogh ZJ, 'The epidemiology of femoral shaft fractures in an inclusive trauma system', ANZ Journal of Surgery, Adelaide, SA (2011) [E3]
2011 Easton RM, Bendinelli C, Enninghorst N, Sisak K, Regan D, Balogh ZJ, 'Prehospital nausea and vomiting revisited', ANZ Journal of Surgery, Adelaide, SA (2011) [E3]
2011 Chan S, Martin A, Hardy BM, Gallagher A, Sokolowsky A, Balogh ZJ, 'Temperature change in the helicopter retrieval of trauma patients', ANZ Journal of Surgery, Adelaide, SA (2011) [E3]
2011 Easton RM, Bendinelli C, Powell A, Enninghorst N, Sisak K, Binks D, Balogh ZJ, 'Recall of pain after acute trauma', ANZ Journal of Surgery, Adelaide, SA (2011) [E3]
2011 Alrahbri R, Bendinelli C, Sisak K, Enninghorst N, Balogh ZJ, 'Intercostal catheter insertion: Are we really doing well?', ANZ Journal of Surgery, Adelaide, SA (2011) [E3]
2010 De Waele J, Balogh Z, Bjorck M, Cheatham M, Ivatury R, Kirkpatrick A, Malbrain M, 'AWARENESS OF AND ATTITUDES REGARDING INTRA-ABDOMINAL HYPERTENSION AND ABDOMINAL COMPARTMENT SYNDROME: RESULTS FROM AN INTERNATIONAL SURVEY (WSACS STUDY 003)', INTENSIVE CARE MEDICINE, Barcelona, SPAIN (2010) [E3]
2010 Balogh ZJ, De Malmanche T, Estens JL, 'Immune monitoring in polytrauma: Report of a pilot study', ANZ Journal of Surgery, Perth, WA (2010) [E3]
2009 Tjeuw MH-Y, Oakley SP, Balogh ZJ, Major GA, 'Bisphosphonate use increases risk of transverse minimal trauma fracture of femoral diaphysis', Arthritis & rheumatism, Philadelphia, Pennsylvania (2009) [E3]
2009 Balogh ZJ, 'Prediction models for Abdominal Compartment Syndrome', Acta Clinica Belgica, Dublin, Ireland (2009) [E3]
2009 Yoshino O, Quail AW, Balogh ZJ, 'Secondary intra-abdominal hypertension: New animal model', Acta Clinica Belgica, Dublin, Ireland (2009) [E3]
Co-authors Tony Quail
2009 Van Wessem K, King KL, Mackay P, Havill K, Balogh ZJ, 'The effect of retroperitoneal haematoma on intra-abdominal hypertension', Acta Clinica Belgica, Dublin, Ireland (2009) [E3]
2009 Balogh ZJ, Martin A, King KL, Van Wessem K, Mackay P, Havill K, 'The clinical significance of postinjury intra-abdominal hypertension', Acta Clinica Belgica, Dublin, Ireland (2009) [E3]
2009 Yoshino O, Quail AW, Balogh ZJ, 'Clinically Relevant Model for Secondary Abdominal Compartment Syndrome', The American Society for the Surgery of Trauma 2009 Poster Abstracts, Pittsburgh, PA (2009) [E3]
Co-authors Tony Quail
2009 Tjeuw M, Oakley S, Van Der Kallen JA, Tan E, Balogh ZJ, Major GA, 'Transverse sub-trochanteric minimal trauma fractures: A relationship to bisphosphonate therapy', Internal Medicine Journal, Wellington, NZ (2009) [E3]
2009 Van Der Kallen JA, McGrath B, Balogh ZJ, Major GA, 'Bisphosphonates reduce refracture rates in patients after neck of femure fractures', Internal medicine journal, Wellington, NZ (2009) [E3]
2007 Mackay P, King KE, Mackenzie S, McDougall D, Evans JA, Balogh ZJ, 'The epidemiology of pelvic fractures: The whole picture', ANZ Journal of Surgery, Whyalla, SA (2007) [E3]
2007 Van Wessem KJP, Mackay PJ, Balogh ZJ, 'Prospective validation of the independent predictors for postinjury intra-abdominal hypertension', ANZ Journal of Surgery, Whyalla, SA (2007) [E3]
2007 Dewar DC, Balogh ZJ, Mackay P, 'Post injury multiple organ failure: The Australian context', ANZ Journal of Surgery, Whyalla, SA (2007) [E3]
2005 McKinley BA, Balogh Z, Kozar RA, Valdivia A, Moore FA, 'GI tonometry is a monitor of onset of ACS', SHOCK, Marco Isl, FL (2005)
2005 Sugrue M, Balogh ZJ, Jamesraj J, Jones F, D'Amours S, 'Continuous abdominal perfusion pressure measurement: New technique', ANZ Journal of Surgery, Noosa, Queensland (2005) [E3]
2005 Balogh ZJ, Jones F, D'Amours S, Parr M, Sugrue M, 'Continuous intra-abdominal pressure measurement technique: A new gold standard', ANZ Journal of Surgery, Noosa, Queensland (2005) [E3]
2005 Peters K, Jones F, Sugrue M, Bauman A, Parr M, Balogh ZJ, 'How reliable is intra-abdominal pressure measurement in Intensive Care?', ANZ Journal of Surgery, Noosa, Queensland (2005) [E3]
2005 Jones F, Peters K, Sugrue M, Balogh ZJ, Frost S, Hillman K, 'Simplified intra-abdominal pressure measurement: Is it valid?', ANZ Journal of Surgery, Noosa, Queensland (2005) [E3]
2004 Balogh Z, Jones F, D'Amours S, Parr M, Sugrue M, 'Continuous intra-abdominal pressure measurement technique', AMERICAN JOURNAL OF SURGERY, Monterey, CA (2004)
DOI 10.1016/j.amjsurg.2004.08.052
Citations Scopus - 109Web of Science - 90
2004 Balogh Z, McKinley BA, Moore FA, 'Gastric tonometry is an early independent predictor of abdominal compartment syndrome', SHOCK, Munich, GERMANY (2004)
2004 Moore FA, Balogh Z, McKinley B, 'Computerized decision support (CDS) for shock resuscitation', SHOCK, Munich, GERMANY (2004)
2004 Balogh Z, Moore FA, McKinley BA, 'The prediction and management of post-injury primary and secondary compartment syndrome', SHOCK, Munich, GERMANY (2004)
2003 Balogh Z, McKinley BA, Cocanour CS, Kozar RA, Cox CS, Moore FA, 'Patients with impending, abdominal compartment syndrome do not respond to early volume loading', AMERICAN JOURNAL OF SURGERY, TUCSON, ARIZONA (2003)
DOI 10.1016/j.amjsurg.2003.09.002
Citations Scopus - 50Web of Science - 44
2003 Balogh Z, McKinley BA, Holcomb JB, Miller CC, Cocanour CS, Kozar RA, et al., 'Both primary and secondary abdominal compartment syndrome can be predicted early and are harbingers of multiple organ failure', JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, ORLANDO, FLORIDA (2003)
DOI 10.1097/01.TA.0000070166.29649.F3
Citations Scopus - 258Web of Science - 211
2003 Suliburk JW, Ware DN, Balogh Z, McKinley BA, Cocanour CS, Kozar RA, Moore FA, 'Vacuum-assisted wound closure achieves early fascial closure of open abdomens after severe trauma', JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, SNOWBIRD, UTAH (2003)
DOI 10.1097/01.TA.0000100218.03754.6A
Citations Scopus - 113Web of Science - 104
2002 Balogh Z, McKinley BA, Cocanour CS, Kozar RA, Holcomb JB, Ware DN, Moore FA, 'Secondary abdominal compartment syndrome is an elusive early complication of traumatic shock resuscitation', AMERICAN JOURNAL OF SURGERY, CORONADO, CALIFORNIA (2002)
DOI 10.1016/S0002-9610(02)01050-4
Citations Scopus - 133Web of Science - 108
1995 Kaszaki J, Wolfard A, Balogh ZJ, Parratt JR, Nagy S, 'The role of nitric oxide in the early hemodynamic changes in hyperdynamic endotoxemia', Shock, Vienna, Austria (1995) [E3]
Show 36 more conferences

Other (4 outputs)

Year Citation Altmetrics Link
2014 Balogh ZJ, 'Trauma Surgery - Forward', ( pp.vii-viii). Verlag, Italy: Springer (2014)
2013 Curtis KA, Mitchell RJ, Chong SS, Balogh ZJ, Clark PT, D'Amours S, et al., 'Injury trends and mortality in adult patients with major trauma in New South Wales REPLY', ( issue.9 pp.481-481): AUSTRALASIAN MED PUBL CO LTD (2013) [C3]
DOI 10.5694/mja12.11623
Citations Web of Science - 1
2013 Balogh ZJ, 'Mastering Orthopedic Techniques: Intra-articular Fractures - Forward', ( pp.xiii). New Delhi, India: Jaypee (2013)
2013 Balogh ZJ, 'Damian John McMahon, MBBS, FRACS: Trauma surgeon and patient advocate (1958-2012) IN MEMORIAM', ( issue.2 pp.701-702): LIPPINCOTT WILLIAMS & WILKINS (2013) [O1]
DOI 10.1097/TA.0b013e31827e22b9
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Grants and Funding

Summary

Number of grants 13
Total funding $1,442,852

Click on a grant title below to expand the full details for that specific grant.


20152 grants / $186,532

HMRI MRSP Infrastructure (15-16) - Traumatology$161,310

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Zsolt Balogh
Scheme NSW MRSP Infrastructure Grant
Role Lead
Funding Start 2015
Funding Finish 2015
GNo G1500827
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

John Hunter Hospital Charitable Trust Grant Round 2015$25,222

Funding body: John Hunter Hospital, Newcastle

Funding body John Hunter Hospital, Newcastle
Project Team
Scheme trust grant
Role Lead
Funding Start 2015
Funding Finish 2015
GNo
Type Of Funding Not Known
Category UNKN
UON Y

20142 grants / $374,658

Evaluation of a tailored online hospital and post-discharge smoking cessation program for orthopaedic trauma surgery patients$364,658

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Associate Professor Billie Bonevski, Professor Zsolt Balogh, Professor Amanda Baker, Professor Ian Harris, Professor John Attia, Conjoint Professor Christopher Doran, Dr Johnson George, Doctor Luke Wolfenden
Scheme Partnership Projects
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1300686
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Neurochemical dysfunction following concussion and mild traumatic brain injury in 10-16 year olds $10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Carolyn Mountford, Professor Zsolt Balogh, Doctor Saadallah Ramadan
Scheme Near Miss Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1301397
Type Of Funding Internal
Category INTE
UON Y

20132 grants / $98,959

The role of mitochondrial DNA in the post-injury inflammatory response following major trauma$73,959

Funding body: Hunter New England Local Health District

Funding body Hunter New England Local Health District
Project Team Professor Zsolt Balogh, Dr Daniel Mcilroy
Scheme Trauma Education and Research Fund Scholarship
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1300217
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

Australian Orthopaedic Association Research Foundation Grant$25,000

Funding body: AOA Australian Orthopaedic Association

Funding body AOA Australian Orthopaedic Association
Project Team
Scheme Research Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo
Type Of Funding Not Known
Category UNKN
UON Y

20122 grants / $46,368

Peri-operative immune-monitoring post trauma$37,500

Funding body: AOA Australian Orthopaedic Association

Funding body AOA Australian Orthopaedic Association
Project Team Professor Zsolt Balogh
Scheme Research Grant
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1101115
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Tissue oxygenation saturation (StO2) changes during intramedullary nailing of lower limb fractures$8,868

Funding body: AOTrauma Asia Pacific

Funding body AOTrauma Asia Pacific
Project Team Professor Zsolt Balogh
Scheme Research Grant
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1101134
Type Of Funding International - Competitive
Category 3IFA
UON Y

20112 grants / $38,393

The immunological impact of orthopaedic trauma operative procedures$30,000

Funding body: John Hunter Hospital Charitable Trust Fund

Funding body John Hunter Hospital Charitable Trust Fund
Project Team
Scheme Research Grant
Role Lead
Funding Start 2011
Funding Finish 2013
GNo
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Australian Pelvic & Acetabular Fracture Database$8,393

Funding body: AOTrauma Asia Pacific

Funding body AOTrauma Asia Pacific
Project Team Professor Zsolt Balogh
Scheme Research Grant
Role Lead
Funding Start 2011
Funding Finish 2011
GNo G1001023
Type Of Funding International - Competitive
Category 3IFA
UON Y

20101 grants / $600,000

Education and Research$600,000

Funding body: Xstrata Coal Australia Pty Ltd

Funding body Xstrata Coal Australia Pty Ltd
Project Team
Scheme Educational Research Grant
Role Lead
Funding Start 2010
Funding Finish 2012
GNo
Type Of Funding Other Public Sector - Local
Category 2OPL
UON Y

20081 grants / $60,942

The effects of resuscitation fluids on intra-abdominal pressure$60,942

Funding body: Hunter New England Area Health Service

Funding body Hunter New England Area Health Service
Project Team Professor Zsolt Balogh
Scheme Trauma Education and Research Fund Scholarship
Role Lead
Funding Start 2008
Funding Finish 2008
GNo G0188616
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

20051 grants / $37,000

Safe driving initative$37,000

Funding body: NRMA Foundation Pty Ltd

Funding body NRMA Foundation Pty Ltd
Project Team
Scheme Donation to the John Hunter Trauma Service
Role Lead
Funding Start 2005
Funding Finish 2005
GNo
Type Of Funding Donation - Aust Non Government
Category 3AFD
UON Y
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Research Supervision

Current Supervision

Commenced Research Title / Program / Supervisor Type
2014 Defining the Immune System and Preventable Mortality in Geriatric Hip Fractures
Surgery, Faculty of Health and Medicine
Principal Supervisor
2012 The Role of Mitochondrial DNA in the Post-Injury "Inflammatory" Response Following Major Trauma
General Medicine, Faculty of Health and Medicine
Principal Supervisor
2011 Understanding the Role of Prehospital Intubation and Advanced Brain Imaging in Patients Suffering from Severe Traumatic Brain Injury
General Medicine, Faculty of Health and Medicine
Principal Supervisor
2010 The Definition of Polytrauma - The Need for International Consensus
General Medicine, Faculty of Health and Medicine
Principal Supervisor
2008 Post Injury Multiple Organ Failure
Surgery, Faculty of Health and Medicine
Principal Supervisor

Past Supervision

Year Research Title / Program / Supervisor Type
2014 The Optimal Timing of Surgical Fracture Stabilization in Trauma Patients
General Medicine, Faculty of Health and Medicine
Principal Supervisor
2011 The Effects of Fluid Resuscitation on Intra-Abdominal Pressure
Surgery, Faculty of Health and Medicine
Principal Supervisor
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News

second hit

Multiple Organ Failure - The Second Hit

August 8, 2014

Professor Zsolt Balogh's trauma research was featured on the ABC's Catalyst program last night.

Professor Zsolt Balogh

Organ failure syndrome

December 18, 2013

The battle to save accident victims in Intensive Care often extends beyond treating the original injury, with multiple organ failure (MOF) presenting a constant threat. While the precise cause of the body's sequential 'shut down' is unknown, results from a recent Hunter Medical Research Institute (HMRI) study may help to solve the puzzle.

Professor Zsolt Balogh

Position

Professor of Surgery
School of Medicine and Public Health
Faculty of Health and Medicine

Contact Details

Email zsolt.balogh@newcastle.edu.au
Phone 4921 4259
Fax 4985 5545

Office

Building John Hunter Hospital
Location Royal Newcastle Centre, Bone & Joint Institute, Level 3, Lookout Road, New Lambton Heights NSW 2305

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