Staff Profile
Career Summary
Biography
Peter Wark is a senior staff specialist in Respiratory and Sleep Medicine at John Hunter Hospital, Newcastle and a conjoint Associate Professor with the University of Newcastle. In addition he is co-director of the Priority Research Centre for Asthma and Respiratory Diseases and a member of the Vaccines Immunology Viruses and Asthma research group at the Hunter Medical Research Institute. He has been a member of the TSANZ executive board since and chairman of the clinical care and resources subcommittee since 2011.
His research interests are in the area of infection and the impact this has on inflammatory airways disease, with a particular interest in viral respiratory infections. His group has developed expertise in identifying respiratory viruses in airway secretions and developing an in-vitro cell culture model of the airway epithelium that we use to model the effect of infection and inflammation. He is the centre director for the John Hunter Adult Cystic Fibrosis clinic that manages 75 adult patients with CF in the context of a multidisciplinary team. He is area director for the oxygen and related products scheme and lead physician for the advanced respiratory failure clinic. He is chairperson for the Hunter New England Local Hospital network respiratory stream, responsible for the provision of respiratory services throughout the Hunter New England area, with a catchment population of 840,000.
Peter qualified as a Bachelor of Medicine at the University of Newcastle, Australia in 1991 and qualified as a specialist in Respiratory and Sleep Medicine as a Fellow of the Royal Australasian College of Physicians in 1999.
From 2001-2005 he was a post doctoral research fellow under an NHMRC Neil Hamilton Fairley Travelling Fellowship at the University of Southampton and University College London, under the supervision of Professors Stephen Holgate, Donna Davies and Sebastian Johnston.
From 1998-2001 he completed a PhD under the supervision of Professors Peter Gibson and Michael Hensley at the University of Newcastle, Australia.
Peter is married to Katrina, and parents to Kirsty, Marden, Jasmine, Sarah, David, Charlotte and Eliza.
Qualifications
- PhD, University of Newcastle, 30/06/2001
- Bachelor of Medicine, University of New South Wales, 31/12/1991
Research
Research keywords
- Airway inflammation
- Asthma
- COPD
- Immunology
- Respiratory Medicine
- Virology
Research expertise
My current research interests include the role of virus infection in acute exacerbations of airways disease and their influence on airway inflammation. Active research programmes include the investigation of innate immune function of the airway epithelium in response to virus infection and the interaction with other components of the cellular immune system. These projects involve the use of invitro cell culture models to study mechanisms of disease and inflammation especially in respect to viral and bacterial infection, the isolation, sequencing and characterisation of respiratory viruses from clinical specimens. Clinical studies currently focus on the effect of infection in acute exacerbations of asthma, COPD and cystic fibrosis lung disease.
I undertook a post-doctoral research project that is collaboration between Professor Stephen Holgate and Professor Sebastian Johnston. The project is titled “Mechanisms of bronchial epithelial cell activation in response to rhinovirus infection in asthma COPD and normal airways. The aim is to characterise the response and interaction of cultured human bronchial epithelial and mesenchymal cells to experimental rhinovirus infection. The aim is to contrast and compare the inflammatory and reparative response in cells from subjects with varying severities of asthma, COPD and normal controls.
During this time I have established expertise with in-vitro culture of tissue cell lines and primary bronchial epithelial cells. In collaboration with Professor Sebastian Johnston I have also established techniques that have enabled me to culture Rhinovirus and infect epithelial cells. We assessed the cytotoxic effect of infection on epithelial cells and determined the mechanisms of cell death using flow cytometry and Annexin binding. In addition the inflammatory response between asthmatic epithelial cells and healthy controls was compared in terms of release of pro-inflammatory mediators, type I interferons and factors that may influence myofibroblast proliferation, by measuring mRNA production using quantifiable PCR in conjunction with protein expression as measured by ELISA. This data has presented at international meetings and is awaiting publication. In the last eighteen months we have received further funding from the UK National Asthma Campaign and the British Medical Association to extend this work examining the effect of infection on an epithelial-mesenchymal co-culture model to determine if there is a relationship between infection and airway wall remodelling and are exploring in greater detail early epithelial intracellular signalling events following infection, particularly in reference to oxidative pathways and interferon ?/? signalling.
My research group specialises in:
1. Primary airway epithelial cell culture, especially in regard to responses to infection and inflammation.
2. Basic mechanisms of innate immune responses pathways, with an emphaisis on epithelial cell responses, dendritic cell responses and innate lymphoid responses.
3. Innate and adaptive immune responses to respiratory virus infection, with a special interest in influenza and rhinovirus
Fields of Research
| Code | Description | Percentage |
|---|---|---|
| 110203 | Respiratory Diseases | 50 |
| 110700 | Immunology | 25 |
| 110804 | Medical Virology | 25 |
Memberships
Body relevant to professional practice.
- Fellow - American Thoracic Society
Editorial Board.
- Editor - International Cochrane collaboration
- Editor - Clinical and experimental allergy
NHMRC Committee
- Member - Translational research
National & International Standards Committees.
- Fellow - Thoracic Society of Australia and New Zealand
Collaboration
Our clinical studies currently focus on the effect of infection in acute exacerbations of asthma, COPD and cystic fibrosis lung disease. Ongoing clinical research programmes are active with Prof Peter Gibson, Dr L Wood. We are currently taking part in a multi-centre RCt of non-CF bronchiectasis in collaboration with Royal Prince Alfred Hospital Sydney and Prince Charles Hospital Brisbane. We are an active site involved in the national influenza surveillance programme "Flucan".
This works involves an effective collaboration between other members of the VIVA group and priority research centre in the areas of clinical research and translational research using animal models with Prof P Hansbro, Prof J Mattes, Prof P Forster.
We have an active NHMRC grant looking at the immunology and susceptibility of virus infection in pregnancy with Prof R Smith.
Teaching
Teaching keywords
- Immunolgy
- Internal medicine
- Respiratory medicine
- Sleep medicine
Teaching expertise
Supervison of honours and PhD students in the areas airway inflammation, infection and respiratory disease.
I am responsible for funding and supervising 2.0 FTE research assistants and 2.0 FTE post-doctoral research fellows. I have supervised two students who have completed and been awarded their PhD, 2 further students who have completed their doctoral studies and will submit their thesis in 2012 and 3 students that completed their honours year. I am currently the primary supervisor for two PhD students and a secondary supervisor for another three.
For the School of Medicine and Public Health, Faculty of Health, University of Newcastle I have regular lecture commitments to years 2, 3, 4 and 5. In addition I act as a clinical tutor for students in year 3, 4 and 5. My direct University teaching commitments are 2.5 hours per week.
Supervision of post graduate students:
I currently supervise 3 students enrolled in PhDs and one student enrolled in a masters degree with the Faculty of Health, University of Newcastle.
I have supervised the following students that have completed and been awarded PhD with the University of Newcastle.
1. Dr Rebecca Forbes awarded 2012
2. Dr Alan Hsu, awarded 2011
2. Dr Shen Yun Adeline Foo, awarded 2011
3. Dr Ahmed Saedsomaelia, awarded 2009
I have supervised the following students that have completed and been awarded honours with the University of Newcastle.
1. Ms Su Ling Loo, First class Honours awarded 2010.
2. Ms Hayley See,
Highlighted Publications
For publications that are currently unpublished or in-press, details are shown in italics.
| Year | Citation | Altmetrics | Link |
|---|---|---|---|
| 2005 | Wark PA, Johnston S, Bucchieri F, Powell R, Puddicombe S, Laza-Stanca V, et al., 'Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus', Journal of Experimental Medicine, 201 937-947 (2005) [C1] DOI: 10.1084/jem.20041901 | ||
| 2006 | Contoli M, Message SD, Laza-Stanca V, Edwards MR, Wark PA, Bartlett N, et al., 'Role of eficient type III interferon-lambda production in asthma exacerbations', Nature Medicine, 12 1023-1026 (2006) [C1] DOI: 10.1038/nm1462 | ||
| 2013 | Collison AM, Hatchwell LM, Verrills NM, Wark PA, Pereira De Siqueira AL, Tooze MK, et al., 'The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity', Nature Medicine, 19 232-237 (2013) [C1] Co-authors: JOERG MATTES, NIKKI VERRILLS, PAUL FOSTER | ||
| 2013 | Vanders RL, Gibson PG, Murphy VE, Wark PAB, 'Plasmacytoid Dendritic Cells and CD8 T Cells From PregnantWomen Show Altered Phenotype and Function Following H1N1/09 Infection', JOURNAL OF INFECTIOUS DISEASES, 208 1062-1070 (2013) [C1] DOI: 10.1093/infdis/jit296 | Author URL Co-authors: PETER GIBSON, VANESSA MURPHY | ||
| 2012 | Hsu A, Parsons KS, Barr I, Lowther S, Middleton D, Hansbro PM, Wark PA, 'Critical role of constitutive type I interferon response in bronchial epithelial cell to influenza infection', PLoS One, 7 e32947 (2012) [C1] DOI: 10.1371/journal.pone.0032947 Co-authors: ALAN HSU, PHILIP HANSBRO |
Publications
For publications that are currently unpublished or in-press, details are shown in italics.
Click on a category title below to expand the list of citations for that specific category.
Chapter (2 outputs)
| Year | Citation | Altmetrics | Link |
|---|---|---|---|
| 2011 | Wark PA, Hayes M, 'Respiratory examination', Clinical Examination: A Problem Based Approach, World Scientific Publishing, Singapore 17-40 (2011) [B2] | ||
| 2010 | Wark PA, Gibson PG, 'Pathogenesis of ABPA', Aspergillosis: From diagnosis to prevention, Springer, Berlin 695-706 (2010) [B1] Co-authors: PETER GIBSON |
Journal article (67 outputs)
| Year | Citation | Altmetrics | Link |
|---|---|---|---|
| 2014 | Wark PAB, Murphy V, Mattes J, 'The interaction between mother and fetus and the development of allergic asthma', Expert Review of Respiratory Medicine, 8 57-66 (2014) DOI: 10.1586/17476348.2014.848795 Co-authors: JOERG MATTES, VANESSA MURPHY | ||
| 2014 | Parsons KS, Hsu AC, Wark PAB, 'TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection.', CLINICAL AND EXPERIMENTAL ALLERGY, 44 91-101 (2014) DOI: 10.1111/cea.12218 | Author URL Co-authors: ALAN HSU | ||
| 2013 | Beckett EL, Stevens RL, Jarnicki AG, Kim RY, Hanish I, Hansbro NG, et al., 'A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis', The Journal of Allergy and Clinical Immunology, 131 752-762 (2013) [C1] Co-authors: JAY HORVAT, MING YANG, NICOLE HANSBRO, PAUL FOSTER, PHILIP HANSBRO, SIMON KEELY | ||
| 2013 | Collison AM, Hatchwell LM, Verrills NM, Wark PA, Pereira De Siqueira AL, Tooze MK, et al., 'The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity', Nature Medicine, 19 232-237 (2013) [C1] Co-authors: JOERG MATTES, NIKKI VERRILLS, PAUL FOSTER | ||
| 2013 | Vanders RL, Gibson PG, Murphy VE, Wark PAB, 'Plasmacytoid Dendritic Cells and CD8 T Cells From PregnantWomen Show Altered Phenotype and Function Following H1N1/09 Infection', JOURNAL OF INFECTIOUS DISEASES, 208 1062-1070 (2013) [C1] DOI: 10.1093/infdis/jit296 | Author URL Co-authors: PETER GIBSON, VANESSA MURPHY | ||
| 2013 | Baines KJ, Hsu AC-Y, Tooze M, Gunawardhana LP, Gibson PG, Wark PAB, 'Novel immune genes associated with excessive inflammatory and antiviral responses to rhinovirus in COPD', RESPIRATORY RESEARCH, 14 (2013) [C1] DOI: 10.1186/1465-9921-14-15 | Author URL Co-authors: ALAN HSU, KATHERINE BAINES, PETER GIBSON | ||
| 2013 | Wark PAB, Tooze M, Powell H, Parsons K, 'Viral and bacterial infection in acute asthma and chronic obstructive pulmonary disease increases the risk of readmission', RESPIROLOGY, 18 996-1002 (2013) [C1] DOI: 10.1111/resp.12099 | Author URL | ||
| 2013 | Cheng AC, Holmes M, Irving LB, Brown SGA, Waterer GW, Korman TM, et al., 'Influenza Vaccine Effectiveness against Hospitalisation with Confirmed Influenza in the 2010-11 Seasons: A Test-negative Observational Study', PLOS ONE, 8 (2013) [C1] | ||
| 2013 | Murphy VE, Powell H, Wark PAB, Gibson PG, 'A Prospective Study of Respiratory Viral Infection in Pregnant Women With and Without Asthma', CHEST, 144 420-427 (2013) [C1] DOI: 10.1378/chest.12-1956 | Author URL Co-authors: PETER GIBSON, VANESSA MURPHY | ||
| 2013 | Vanders RL, Gibson PG, Wark PAB, Murphy VE, 'Alterations in inflammatory, antiviral and regulatory cytokine responses in peripheral blood mononuclear cells from pregnant women with asthma', RESPIROLOGY, 18 827-833 (2013) [C1] DOI: 10.1111/resp.12068 | Author URL Co-authors: PETER GIBSON, VANESSA MURPHY | ||
| 2012 | Sukkar MB, Ullah MA, Gan WJ, Wark PA, Chung KF, Hughes JM, et al., 'RAGE: a new frontier in chronic airways disease', British Journal of Pharmacology, 167 1161-1176 (2012) [C1] | ||
| 2012 | Sukkar MB, Wood LG, Tooze MK, Simpson JL, McDonald VM, Gibson PG, Wark PA, 'Soluble RAGE is deficient in neutrophilic asthma and COPD', European Respiratory Journal, 39 721-729 (2012) [C1] Co-authors: JODIE SIMPSON, LISA WOOD, PETER GIBSON, VANESSA MCDONALD | ||
| 2012 | Hsu A, See HV, Hansbro PM, Wark PA, 'Innate immunity to influenza in chronic airways diseases', Respirology, 17 1166-1175 (2012) [C1] Co-authors: ALAN HSU, PHILIP HANSBRO | ||
| 2012 | Bozinovski S, Uddin M, Vlahos R, Thompson M, McQualter JL, Merritt A-S, et al., 'Serum amyloid A opposes lipoxin A(4) to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease', Proceedings of the National Academy of Sciences of the United States of America, 109 935-940 (2012) [C1] | ||
| 2012 | Hsu A, Parsons KS, Barr I, Lowther S, Middleton D, Hansbro PM, Wark PA, 'Critical role of constitutive type I interferon response in bronchial epithelial cell to influenza infection', PLoS One, 7 e32947 (2012) [C1] DOI: 10.1371/journal.pone.0032947 Co-authors: ALAN HSU, PHILIP HANSBRO | ||
| 2012 | Hurt AC, Hardie K, Wilson NJ, Deng YM, Osbourn M, Leang SK, et al., 'Characteristics of a widespread community cluster of H275Y Oseltamivir-Resistant A (H1N1)pdm09 influenza in Australia', Journal of Infectious Diseases, 206 148-157 (2012) [C1] Co-authors: CRAIG DALTON, DAVID DURRHEIM | ||
| 2012 | Vanders RL, Wark PA, Murphy VE, Gibson PG, 'Pregnant women have attenuated innate interferon responses to 2009 pandemic influenza a virus subtype H1N1', Journal of Infectious Diseases, 206 646-653 (2012) [C1] Co-authors: PETER GIBSON, VANESSA MURPHY | ||
| 2012 | Ryan NM, Vertigan AE, Ferguson JK, Wark PA, Gibson PG, 'Clinical and physiological features of postinfectious chronic cough associated with H1N1 infection', Respiratory Medicine, 106 138-144 (2012) [C1] DOI: 10.1016/j.rmed.2011.10.007 Co-authors: NICOLE RYAN, PETER GIBSON | ||
| 2012 | Wark PA, Tooze M, Cheese L, Whitehead BF, Gibson PG, Wark K, McDonald VM, 'Viral infections trigger exacerbations of cystic fibrosis in adults and children', European Respiratory Journal, 40 510-512 (2012) [C1] DOI: 10.1183/09031936.00202311 Co-authors: PETER GIBSON, VANESSA MCDONALD | ||
| 2012 | Wark PA, 'Airway inflammation in asthma, a single measurement is not enough', Respirology, 17 393-394 (2012) [C3] | ||
| 2011 | Cheng AC, Kotsimbos T, Kelly HA, Irving LB, Bowler SD, Brown SGA, et al., 'Effectiveness of H1N1/09 monovalent and trivalent influenza vaccines against hospitalization with laboratory-confirmed H1N1/09 influenza in Australia: A test-negative case control study', Vaccine, 29 7320-7325 (2011) [C1] | ||
| 2011 | Hsu A, Barr I, Hansbro PM, Wark PA, 'Human influenza is more effective than Avian influenza at antiviral suppression in airway cells', American Journal of Respiratory Cell and Molecular Biology, 44 906-913 (2011) [C1] Co-authors: ALAN HSU, PHILIP HANSBRO | ||
| 2011 | Wood LG, Simpson JL, Wark PA, Powell H, Gibson PG, 'Characterization of innate immune signalling receptors in virus-induced acute asthma', Clinical and Experimental Allergy, 41 640-648 (2011) [C1] DOI: 10.1111/j.1365-2222.2010.03669.x Co-authors: JODIE SIMPSON, LISA WOOD, PETER GIBSON | ||
| 2011 | Katelaris CH, Linneberg A, Magnan A, Thomas WR, Wardlaw AJ, Wark PA, 'Developments in the field of allergy in 2010 through the eyes of Clinical and Experimental Allergy', Clinical and Experimental Allergy, 41 1690-1710 (2011) [C3] | ||
| 2011 | Wark PA, 'Tiotropium reduced exacerbations more than salmeterol in moderate-to-very severe COPD', Annals of Internal Medicine, 155 3 (2011) [C3] | ||
| 2010 | Wark PA, 'Viral and bacterial interactions in pneumonia', Expert Review of Respiratory Medicine, 4 221-228 (2010) [C1] DOI: 10.1586/ers.10.5 | ||
| 2010 | Osei-Kumah A, Wark PA, Smith R, Clifton VL, 'Asthma during pregnancy alters immune cell profile and airway epithelial chemokine release', Inflammation Research, 59 349-358 (2010) [C1] DOI: 10.1007/s00011-009-0102-y Co-authors: ROGER SMITH, vicki clifton | ||
| 2010 | Wood LG, Wark PA, Garg ML, 'Antioxidant and anti-inflammatory effects of resveratrol in airway disease', Antioxidants & Redox Signaling, 13 1535-1548 (2010) [C1] Co-authors: LISA WOOD, MANOHAR GARG | ||
| 2010 | Reddel HK, Gibson PG, Peters MJ, Wark PA, Sand IB, Hoyos CM, Jenkins CR, 'Down-titration from high-dose combination therapy in asthma: Removal of long-acting b2-agonist', Respiratory Medicine, 104 1110-1120 (2010) [C1] DOI: 10.1016/j.rmed.2010.04.003 Co-authors: PETER GIBSON | ||
| 2009 | Wark PA, McDonald VM, 'Nebulised hypertonic saline for cystic fibrosis', Cochrane Database of Systematic Reviews, - CD001506 (2009) [C1] DOI: 10.1002/14651858.cd001506.pub3 Co-authors: VANESSA MCDONALD | ||
| 2009 | Saedi Some Olia A, Wood LG, Garg ML, Gibson PG, Wark PA, 'Anti-inflammatory effects of long-chain n-3 PUFA in rhinovirus-infected cultured airway epithelial cells', British Journal of Nutrition, 101 533-540 (2009) [C1] DOI: 10.1017/s0007114508025798 Co-authors: LISA WOOD, MANOHAR GARG, PETER GIBSON | ||
| 2009 | Wark PA, Grissell TV, Davies BL, See HV, Gibson PG, 'Diversity in the bronchial epithelial cell response to infection with different rhinovirus strains', Respirology, 14 180-186 (2009) [C1] DOI: 10.1111/j.1440-1843.2009.01480.x Co-authors: PETER GIBSON | ||
| 2009 | Saedi Some Olia A, Wood LG, Garg ML, Gibson PG, Wark PA, 'Lycopene enrichment of cultured airway epithelial cells decreases the inflammation induced by rhinovirus infection and lipopolysaccharide', Journal of Nutritional Biochemistry, 20 577-585 (2009) [C1] DOI: 10.1016/j.jnutbio.2008.06.001 Co-authors: LISA WOOD, MANOHAR GARG, PETER GIBSON | ||
| 2008 | Hansbro NG, Horvat JC, Wark PA, Hansbro PM, 'Understanding the mechanisms of viral induced asthma: New therapeutic directions', Pharmacology & Therapeutics, 117 313-353 (2008) [C1] DOI: 10.1016/j.pharmthera.2007.11.002 Co-authors: JAY HORVAT, NICOLE HANSBRO, PHILIP HANSBRO | ||
| 2008 | Oliver BGG, Lim S, Wark PA, Laza-Stanca V, King N, Black JL, et al., 'Rhinovirus exposure impairs immune responses to bacterial products in human alveolar macrophages', Thorax, 63 519-525 (2008) [C1] | ||
| 2008 | Simpson JL, Wark PA, 'The role of exhaled nitric oxide and exhaled breath condensates in evaluating airway inflammation in asthma', Expert Opinion on Medical Diagnostics, 2 607-620 (2008) [C1] Co-authors: JODIE SIMPSON | ||
| 2008 | Saedi Some Olia A, Wood LG, Garg ML, Gibson PG, Wark PA, 'Supplementation of long chain N-3 polyunsaturated fatty acids increases the utilization of lycopene in cultured airway epithelial cells', Journal of Food Lipids, 15 421-432 (2008) [C1] DOI: 10.1111/j.1745-4522.2008.00130.x Co-authors: LISA WOOD, MANOHAR GARG, PETER GIBSON | ||
| 2008 | See HV, Wark PA, 'Innate immune response to viral infection of the lungs', Paediatric Respiratory Reviews, 9 243-250 (2008) [C1] | ||
| 2008 | Wark PA, 'Guest editorial', Paediatric Respiratory Reviews, 9 233-235 (2008) [C3] | ||
| 2007 | Weckmann M, Collison A, Simpson JL, Kopp MV, Wark PA, Smyth MJ, et al., 'Critical link between TRAIL and CCL20 for the activation of T(H)2 cells and the expression of allergic airway disease', Nature Medicine, 13 1308-1315 (2007) [C1] DOI: 10.1038/nm1660 Co-authors: JODIE SIMPSON, JOERG MATTES, NICOLE HANSBRO, PAUL FOSTER, PETER GIBSON | ||
| 2007 | Wark PA, Bucchieri F, Johnston SL, Gibson PG, Hamilton L, Mimica J, et al., 'IFN-gamma-induced protein 10 is a novel biomarker of rhinovirus-induced asthma exacerbations', Journal of Allergy and Clinical Immunology, 120 586-593 (2007) [C1] DOI: 10.1016/j.jaci.2007.04.046 Co-authors: JOHN ATTIA, PETER GIBSON | ||
| 2006 | Wark PA, Gibson PG, 'Asthma exacerbations 3: Pathogenesis', Thorax, 61 909-915 (2006) [C1] Co-authors: PETER GIBSON | ||
| 2006 | Contoli M, Message SD, Laza-Stanca V, Edwards MR, Wark PA, Bartlett N, et al., 'Role of eficient type III interferon-lambda production in asthma exacerbations', Nature Medicine, 12 1023-1026 (2006) [C1] DOI: 10.1038/nm1462 | ||
| 2006 | Wark PA, 'Safety concerns with salmeterool', Australian Prescriber, 29 118-119 (2006) [C3] | ||
| 2005 | Wood LG, Garg ML, Simpson JL, Mori TA, Croft KD, Wark PA, Gibson PG, 'Induced sputum 8-isoprostane concentrations in inflammatory airway diseases', American Journal of Respiratory and Critical Care Medicine, 171 426-430 (2005) [C1] DOI: 10.1164/rccm.200408-1010OC Co-authors: JODIE SIMPSON, LISA WOOD, MANOHAR GARG, PETER GIBSON | ||
| 2005 | Wark PA, Johnston S, Bucchieri F, Powell R, Puddicombe S, Laza-Stanca V, et al., 'Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus', Journal of Experimental Medicine, 201 937-947 (2005) [C1] DOI: 10.1084/jem.20041901 | ||
| 2004 | Wark PA, 'Pathogenesis of allergic bronchopulmonary aspergillosis and an evidence-based review of azoles in treatment', Respiratory Medicine, 98 915-923 (2004) [C1] | ||
| 2004 | Wark PA, 'Bronchitis (acute)', Clinical Evidence, 12 (2004) [C3] | ||
| 2003 | Simpson JL, Moric I, Wark PA, Johnston S, Gibson PG, 'Use of induced sputum for the diagnosis of influenza and infections in asthma: a comparison of diagnostic techniques', Journal of Clinical Virology, 339-346 (2003) [C1] DOI: 10.1016/S1386-6532(02)00084-7 Co-authors: JODIE SIMPSON, PETER GIBSON | ||
| 2003 | Gibson PG, Wark PA, Simpson JL, Meldrum CJ, Meldrum S, Saltos N, Boyle MJ, 'Induced sputum IL-8 gene expression, neutrophil influx and MMP-9 in allergic bronchopulmonary aspergillosis', European Respiratory Journal, 21 582-588 (2003) [C1] DOI: 10.1183/09031936.03.00001803 Co-authors: JODIE SIMPSON, PETER GIBSON | ||
| 2003 | Wark PA, Hensley MJ, Saltos N, Boyle MJ, Toneguzzi R, Simpson JL, et al., 'Anti-inflammatory effect of itraconazole in stable allergic bronchopulmonary aspergillosis: A randomized controlled trial', The Journal of Allergy and Clinical Immunology, 111 952-957 (2003) [C1] Co-authors: JODIE SIMPSON, PETER GIBSON, michael hensley | ||
| 2002 | Wark PA, Johnston S, Moric I, Simpson JL, Hensley MJ, Gibson PG, 'Neutrophil degranulation and cell lysis is associated with clinical severity in virus-induced asthma', The European Respiratory Journal, 19 68-75 (2002) [C1] Co-authors: JODIE SIMPSON, PETER GIBSON, michael hensley | ||
| 2002 | Wark PA, Simpson JL, Hensley MJ, Gibson PG, 'Airway inflammation in thunderstorm asthma', Clinical and Experimental Allergy, 32 1750-1756 (2002) [C1] Co-authors: JODIE SIMPSON, PETER GIBSON, michael hensley | ||
| 2002 | Wark PA, Johnston S, Simpson JL, Hensley MJ, Gibson PG, 'Chlamydia pneumoniae immunoglobulin A reactivation and airway inflammation in acute asthma', The European Respiratory Journal, 20 834-840 (2002) [C1] Co-authors: JODIE SIMPSON, PETER GIBSON, michael hensley | ||
| 2002 | Simpson JL, Gibson PG, Wark PA, 'Optimization of sputum-processing methods for the measurement of interleukin-5: Effects of protease inhibition', Respirology, 7 111-116 (2002) [C1] Co-authors: JODIE SIMPSON, PETER GIBSON | ||
| 2001 | Gibson PG, Simpson J, Chalmers AC, Toneguzzi R, Wark PA, Wilson AJ, Hensley MJ, 'Airway Eosinophilia is associated with Wheeze but is uncommon in Children with Persistent Cough and Frequent Chest Colds', American Journal of Respiratory and Critical Care Medicine, 164 977-981 (2001) [C1] Co-authors: AMANDA WILSON, ANITA CHALMERS, JODIE SIMPSON, PETER GIBSON, michael hensley | ||
| 2001 | Wark PA, Gibson PG, Johnston S, 'Exacerbations of asthma: addressing the triggers and treatments', Monaldi Archives for Chest Disease, 56 429-435 (2001) [C1] Co-authors: PETER GIBSON | ||
| 2001 | Wark PA, Simpson J, Hensley MJ, Gibson PG, 'Safety of sputum induction with isotonic saline in adults with acute severe asthma', Clinical and Experimental Allergy, 31 1745-1753 (2001) [C1] Co-authors: JODIE SIMPSON, PETER GIBSON, michael hensley | ||
| 2001 | Wark PA, Gibson PG, 'Allergic bronchopulmonary aspergillosis: New concepts of pathogenesis and treatment', Respirology, 6 1-7 (2001) [C2] Co-authors: PETER GIBSON | ||
| 2000 | Wark PA, Gibson PG, Fakes K, 'Induced sputum eosinophils in the assessment of asthma and chronic cough*', Respirology, 5 51-57 (2000) [C1] Co-authors: PETER GIBSON | ||
| 2000 | Wark PA, Saltos N, Simpson J, Slater S, Hensley MJ, Gibson PG, 'Induced sputum easinophils and neutrophils and bronchiectasis severity in allergic bronchopulmonary aspergillosis', European Respiratory Journal, 16 1095-1101 (2000) [C1] Co-authors: JODIE SIMPSON, PETER GIBSON, michael hensley | ||
| 2000 | Wark PA, Wilson A, Gibson PG, 'Azoles for allergic bronchopulmonary aspergillosis', The Cochrane Library, 1-9 (2000) [C1] Co-authors: PETER GIBSON | ||
| Show 64 more | |||
Review (1 outputs)
| Year | Citation | Altmetrics | Link |
|---|---|---|---|
| 2004 | Wark PA, Gibson PG, Wilson AJ, 'Azoles for Allergic Bronchopulmonary Aspergillosis Associated With Asthma', Cochrane Database of Systematic Reviews (2004) [D1] Co-authors: AMANDA WILSON, PETER GIBSON |
Conference (79 outputs)
| Year | Citation | Altmetrics | Link |
|---|---|---|---|
| 2014 | Hsu A, Parsons K, Fujita T, Hansbro P, Wark P, 'Critical role of PKR in antiviral stress granule and IFN-beta enhanceosome formation, and is impaired in chronic obstructive pulmonary disease', CYTOKINE, Melbourne, AUSTRALIA (2014) [E3] DOI: 10.1016/j.cyto.2014.07.088 | Author URL Co-authors: ALAN HSU, PHILIP HANSBRO | ||
| 2014 | Hsu A, Parsons K, Hansbro P, Wark P, 'Enhanced PI3K activity leads to decreased IFN-beta response to influenza infection in chronic obstructive pulmonary disease', CYTOKINE, Melbourne, AUSTRALIA (2014) [E3] DOI: 10.1016/j.cyto.2014.07.089 | Author URL Co-authors: ALAN HSU, PHILIP HANSBRO | ||
| 2014 | Hsu A, Parsons K, Hansbro P, Wark P, Wark P, 'IMPAIRED FORMATION OF ANTIVIRAL STRESS GRANULE AND INTERFERON-BETA ENHANCEOSOME LEADS TO REDUCED ANTIVIRAL RESPONSES TO INFLUENZA IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE', RESPIROLOGY (2014) [E3] Co-authors: ALAN HSU, PHILIP HANSBRO | ||
| 2014 | Fathi F, Hsu A, Parsons K, Keely S, Wood L, Wark P, 'OXIDATIVE STRESS IMPAIRS MITOCHONDRIAL FUNCTION AND LEADS TO DEFICIENT ANTIVIRAL RESPONSES IN PRIMARY BRONCHIAL EPITHELIAL CELLS', RESPIROLOGY (2014) [E3] DOI: 10.1111/resp.12263_3 | Author URL Co-authors: ALAN HSU, LISA WOOD, SIMON KEELY | ||
| 2014 | Collison A, Hatchwell L, Girkin J, Li J, Parsons K, Bartlett N, et al., 'REDUCED TLR7 EXPRESSION MAY UNDERPIN IMPAIRED RESPONSE TO VIRAL INFECTION IN ASTHMA', RESPIROLOGY (2014) [E3] DOI: 10.1111/resp.12263_5 | Author URL Co-authors: JOERG MATTES, PAUL FOSTER | ||
| 2014 | Starkey M, Hanish I, Dua K, Nair P, Haw T, Hsu A, et al., 'Interleukin-13 predisposes mice to more severe influenza infection by suppressing interferon responses and activating microRNA-21/PI3K', CYTOKINE, Melbourne, AUSTRALIA (2014) [E3] DOI: 10.1016/j.cyto2014.07.182 | Author URL Co-authors: ALAN HSU, DARRYL KNIGHT, JAY HORVAT, PAUL FOSTER, PHILIP HANSBRO | ||
| 2013 | Zhong H, Simpson JL, Wood LG, Wark PAB, 'COPD PERIPHERAL BLOOD NEUTROPHILS HAVE ENHANCED RELEASE OF IL-1B WHEN STIMULATED', RESPIROLOGY (2013) [E3] Co-authors: JODIE SIMPSON, LISA WOOD | ||
| 2013 | Hansbro P, Beckett E, Stevens R, Jarnicki A, Kim R, Hanish I, et al., 'A short-term model of COPD identifies a role for mast cell tryptase', JOURNAL OF IMMUNOLOGY, Honolulu, HI (2013) [E3] Co-authors: JAY HORVAT, MING YANG, NICOLE HANSBRO, PAUL FOSTER, PHILIP HANSBRO, SIMON KEELY | ||
| 2012 | Zhong H, Simpson JL, Wood LG, Wark PA, 'Different responses of blood neutrophils from COPD', Respirology, Hong Kong (2012) [E3] Co-authors: JODIE SIMPSON, LISA WOOD | ||
| 2012 | Wark PA, Tooze MK, Hsu A, Parsons KS, 'Silencing of MDA5 and TLR3 does not reduce innate immune responses to rhinovirus in defective asthmatic bronchial epithelial cells', Respirology, Canberra, ACT (2012) [E3] Co-authors: ALAN HSU | ||
| 2012 | Patel S, McKay K, Cooper P, Sorrell T, Andresen D, Middleton P, et al., 'Fungal colonisation and clinical associations in children with cystic fibrosis', Mycoses, Berlin, Germany (2012) [E3] | ||
| 2012 | Zhong H, Simpson JL, Wood LG, Wark PA, 'Activation of human neutrophils exposed to cigarette smoke extract: A comparison of COPD patients versus healthy non-smokers', Respirology, Canberra, ACT (2012) [E3] Co-authors: JODIE SIMPSON, LISA WOOD | ||
| 2012 | Parsons KS, Tooze MK, Grissell TV, Bell N, Chapman JN, Ryan J, et al., 'Patterns (2007-2009) of respiratory viruses isolated from acute exacerbations of airways disease', Respirology, Canberra, ACT (2012) [E3] Co-authors: PETER GIBSON | ||
| 2012 | See HV, Simpson JL, Hansbro PM, Wark PA, 'Stable COPD patients have less rhinovirus-induced intracellular innate cytokines detected in PBMCS compared to healthy adults', Respirology, Canberra, ACT (2012) [E3] Co-authors: JODIE SIMPSON, PHILIP HANSBRO | ||
| 2012 | Addnan FH, Wood LG, Garg ML, Wark PA, 'Antiviral effects of antioxidants on human rhinovirus', Respirology, Canberra, ACT (2012) [E3] Co-authors: LISA WOOD, MANOHAR GARG | ||
| 2012 | Wark PA, Tooze MK, Cheese L, Whitehead BF, Gibson PG, McDonald VM, 'Viral infections trigger CF exacerbations and worsen infection with P Aeruginosa in adults and children', Respirology, Canberra, ACT (2012) [E3] Co-authors: PETER GIBSON, VANESSA MCDONALD | ||
| 2012 | McDonald VM, Wark PA, Roberts M, Spencer LM, Alison JA, Wood LG, Gibson PG, 'Development and audience testing of a COPD education DVD', Respirology, Canberra, ACT (2012) [E3] Co-authors: LISA WOOD, PETER GIBSON, VANESSA MCDONALD | ||
| 2012 | Hsu A, Parsons KS, Barr I, Hansbro PM, Wark PA, 'Deficient antiviral responses to influenza in primary bronchial epithelial cells of chronic obstructive pulmonary disease', Respirology, Canberra, ACT (2012) [E3] Co-authors: ALAN HSU, PHILIP HANSBRO | ||
| 2011 | Addnan FH, Wark PA, Wood LG, Garg ML, 'Effects of antioxidants on inflammation and apoptosis in rhinovirus-infected airway epithelial cells', Australasian Medical Journal, Queenstown, NZ (2011) [E3] Co-authors: LISA WOOD, MANOHAR GARG | ||
| 2011 | Addnan FH, Wark PA, Wood LG, Garg ML, 'Antiviral activity of antioxidants against rhinovirus infection', Australasian Medical Journal, Queenstown, NZ (2011) [E3] Co-authors: LISA WOOD, MANOHAR GARG | ||
| 2011 | Smart JM, Wark PA, Wood LG, 'Investigating the obesity paradox in ex-smokers', Australasian Medical Journal, Queenstown, NZ (2011) [E3] Co-authors: LISA WOOD | ||
| 2011 | Wark PA, Parsons KS, Tooze MK, Hsu A, 'MDA5 is crucial inhibiting rhinovirus replication in primary bronchial epithelial cells', Respirology, Perth, WA (2011) [E3] Co-authors: ALAN HSU | ||
| 2011 | See HV, Simpson JL, Hansbro PM, Wark PA, 'COPD patients PBMCS have an impaired immune response to phinovirus-infected bronchial epithelium', Respirology, Perth, WA (2011) [E3] Co-authors: JODIE SIMPSON, PHILIP HANSBRO | ||
| 2011 | Ryan NM, Vertigan AE, Ferguson JK, Wark PA, Gibson PG, 'Investigation and characterization of persistent cough associated with H1N1 2009 influenza', Respirology, Perth, WA (2011) [E3] Co-authors: NICOLE RYAN, PETER GIBSON | ||
| 2011 | Parsons KS, Tooze MK, Hsu A, Wark PA, 'Oxidative stress induces mitochondrial dusfunction in airway epithelial cells and impairs response to rhinovirus', Respirology, Perth, WA (2011) [E3] Co-authors: ALAN HSU | ||
| 2011 | Vanders RL, Gibson PG, Murphy VE, Wark PA, 'Reduced antiviral interferons during pregnancy explains susceptibility to influenza virus infection', Respirology, Perth, WA (2011) [E3] Co-authors: PETER GIBSON, VANESSA MURPHY | ||
| 2011 | Baines KJ, Tooze MK, Wark PA, 'Rhinovirus infected airway epithelial cells have an increased pro-inflammatory response in COPD', Respirology, Perth, WA (2011) [E3] Co-authors: KATHERINE BAINES | ||
| 2011 | Hatchwell LM, Collison AM, Pereira De Siqueira AL, Foster PS, Verrills NM, Don A, et al., 'A novel E3 ubiquitin ligase links rhinovirus infection to exacerbation of asthma', Respirology, Perth, WA (2011) [E3] Co-authors: JOERG MATTES, NIKKI VERRILLS, PAUL FOSTER | ||
| 2011 | Sukkar M, Wood LG, Tooze MK, Simpson JL, McDonald VM, Gibson PG, Wark PA, 'Soluble RAGE is deficient in neutrophilic asthma and COPD', Respirology, Perth, WA (2011) [E3] DOI: 10.1183/09031936.00022011 Co-authors: JODIE SIMPSON, LISA WOOD, PETER GIBSON, VANESSA MCDONALD | ||
| 2011 | Zhong H, Tooze MK, Wood LG, Simpson JL, Wark PA, 'Effect of cigarette smoke extract on neutrophils isolated from human peripheral blood', Respirology, Perth, WA (2011) [E3] Co-authors: JODIE SIMPSON, LISA WOOD | ||
| 2011 | Sukkar MB, Wood LG, Tooze MK, Simpson JL, McDonald VM, Gibson PG, Wark PA, 'Deficiency of srage in asthma and COPD is selectively associated with neutrophilic airway inflammation', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3] Co-authors: JODIE SIMPSON, LISA WOOD, PETER GIBSON, VANESSA MCDONALD | ||
| 2011 | Bozinovski S, Uddin M, Vlahos R, Thompson M, Merritt A-S, Wark PA, et al., 'Serum amyloid A augments mucosal immunity by opposing resolving Lipoxina4 signaling in chronic lung disease', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3] | ||
| 2010 | Vanders RL, Gibson PG, Murphy VE, Wark PA, 'Reduced anti-viral responses: Why pregnant women have increased susceptibility to respiratory virus infection', American Journal of Respiratory and Critical Care Medicine, New Orleans, LO (2010) [E3] Co-authors: PETER GIBSON, VANESSA MURPHY | ||
| 2010 | Yan X, He S, Gangireddy SR, Gibson PG, Wark PA, 'Monocyte derived dendritic cells from COPD patients and their therapeutic potential', Respirology, Brisbane, QLD (2010) [E3] Co-authors: PETER GIBSON | ||
| 2010 | Smart JM, Wark PA, McDonald VM, Wood LG, 'CRP, body composition and lung function in ex-smokers', Respirology, Brisbane, QLD (2010) [E3] Co-authors: LISA WOOD, VANESSA MCDONALD | ||
| 2010 | Smart JM, Wark PA, McDonald VM, Wood LG, 'Low levels of body fat and obstructive airway disease in ex-smokers', Proceedings of the Nutrition Society of Australia, Perth (2010) [E3] Co-authors: LISA WOOD, VANESSA MCDONALD | ||
| 2010 | Pretto JJ, McDonald VM, Wark PA, Hensley MJ, 'An audit of clinical practice for COPD hospital admissions', Respirology, Brisbane, QLD (2010) [E3] Co-authors: VANESSA MCDONALD, michael hensley | ||
| 2010 | Parsons KS, Tooze MK, Gangireddy SR, Wark PA, 'Cigarette smoke extract impairs epithelial cell antiviral response to rhinovirus infection', Respirology, Brisbane, QLD (2010) [E3] | ||
| 2010 | McDonald VM, Pretto JJ, Wark PA, Hensley MJ, 'Low acuity COPD admissions: Are they avoidable?', Respirology, Brisbane, QLD (2010) [E3] Co-authors: VANESSA MCDONALD, michael hensley | ||
| 2010 | Gangireddy SR, Parsons KS, Tooze MK, Wark PA, 'The innate immune response to rhinovirus in bronchial epithelial cells is predominately controlled by signalling initiated via MDA-5', Respirology, Brisbane, QLD (2010) [E3] | ||
| 2010 | Vanders RL, Gibson PG, Murphy VE, Wark PA, 'Reduced anti-viral responses: Why pregnant women have increased susceptiblty to respiratory virus infection', Respirology, Brisbane, QLD (2010) [E3] Co-authors: PETER GIBSON, VANESSA MURPHY | ||
| 2010 | Smart JM, Wark PA, McDonald VM, Wood LG, 'Body composition in ex-smokers with and without airflow obstruction', Obesity Research and Clinical Practice, Sydney, NSW (2010) [E3] Co-authors: LISA WOOD, VANESSA MCDONALD | ||
| 2010 | Pretto JJ, McDonald VM, Wark PA, Hensley MJ, 'An audit of clinical practice for COPD hospital admissions to eight Australian public hospitals', European Respiratory Society Annual Congress 2010. Abstracts, Barcelona, Spain (2010) [E3] Co-authors: VANESSA MCDONALD, michael hensley | ||
| 2009 | Southern KW, Smyth A, Wark PA, Ryan G, Dwan K, Yates N, et al., 'The impact of Cochrane systematic reviews on cyctic fibrosis care', Pediatric Pulmonology, Minneapolis (2009) [E3] DOI: 10.1002/ppul.21133 | ||
| 2009 | Parsons KS, Gangireddy SR, Hansbro PM, Barr I, Wark PA, 'Response of primary bronchial epithelial cells to infection with human influenza virus', Respirology, Darwin, NT (2009) [E3] DOI: 10.1111/j.1440-1843.2009.01502_7.x Co-authors: PHILIP HANSBRO | ||
| 2009 | Wark PA, Parsons KS, Ryan J, Grissell T, Bell N, Chapman JN, Gibson PG, 'Seasonal patterns (2004-2007) of respiratory viruses isolated with acute airways disease', Respirology, Darwin, NT (2009) [E3] DOI: 10.1111/j.1440-1843.2009.01503_1.x Co-authors: PETER GIBSON | ||
| 2009 | Clarke J, Cookson K, Gendle L, Bentley L, Wark PA, McDonald VM, 'Evaluation of patient acceptance of CF segregation and isolation policies', Respirology, Darwin, NT (2009) [E3] DOI: 10.1111/j.1440-1843.2009.01502_7.x Co-authors: VANESSA MCDONALD | ||
| 2009 | Wark PA, Oldham RA, Brooks C, Simpson JL, Douwes J, 'Airway neutrophilia in chronic obstructive pulmonary disease (COPD) and asthma are associated with lower lung function and the presence of pathogenic bacteria', Respirology, Darwin, NT (2009) [E3] DOI: 10.1111/j.1440-1843.2009.01502_7.x Co-authors: JODIE SIMPSON | ||
| 2009 | Foo A, Lam CE, Wark PA, Foster PS, Phipps S, 'Immune mechanisms that promote the development of inducible bronchus-associated lymphoid tissue (iBALT)', American Journal of Respiratory and Critical Care Medicine, San Diego, CA (2009) [E3] Co-authors: PAUL FOSTER | ||
| 2009 | Addnan FH, Wood LG, Garg ML, Wark PA, 'Resveratrol prevents hydrogen peroxide induced cytotoxicity', Proceedings of the Nutrition Society of Australia, Newcastle, NSW (2009) [E3] Co-authors: LISA WOOD, MANOHAR GARG | ||
| 2009 | Twaddell S, Loewenthal MR, Gibson PG, Saltos N, Wark PA, 'Individualised aminoglycoside dosing in adult patients with cystic fibrosis improves pharmacokinetic parameters', Respirology, Darwin, NT (2009) [E3] DOI: 10.1111/j.1440-1843.2009.01503_1.x Co-authors: PETER GIBSON | ||
| 2009 | Wark PA, Hsu A, Hansbro PM, 'Innate immune response of bronchial epithelial cells to infection with influenza', Journal of Immunology, Seattle, WASH. (2009) [E3] Co-authors: ALAN HSU, PHILIP HANSBRO | ||
| 2009 | Wark PA, See HV, Simpson JL, Vanders RL, Hansbro PM, 'Peripheral blood monocytes (PBMCs) display innate antiviral response to rhinovirus (RV) infected bronchial epithelial cells', Journal of Immunology, Seattle, WASH. (2009) [E3] Co-authors: JODIE SIMPSON, PHILIP HANSBRO | ||
| 2009 | Baines KJ, Grissell TV, Gibson PG, Wark PA, 'Molecular mechanisms of rhinovirus infection of primary bronchial epithelial cells', Respirology, Darwin, NT (2009) [E3] DOI: 10.1111/j.1440-1843.2009.01503_1.x Co-authors: KATHERINE BAINES, PETER GIBSON | ||
| 2009 | Hsu A, Hansbro PM, Barr I, Wark PA, 'Innate immune response of bronchial epithelial cells to human and avian influenza virus', Respirology, Darwin, NT (2009) [E3] Co-authors: ALAN HSU, PHILIP HANSBRO | ||
| 2008 | Oliver BGG, Kuo C, Johnston SL, King NJC, Wark PA, Lim S, et al., 'Rhinovirus infection of primary human airway smooth muscle cells and fibroblasts induces extracellular matrix deposition', American Journal of Respiratory and Critical Care Medicine, Toronto, ONT (2008) [E3] | ||
| 2008 | Wark PA, Oldham RA, Simpson JL, Douwes J, 'Endotoxin levels are higher in the bronchoalveolar lavage of ex-smokers compared to never smokers', Respirology, Melbourne, VIC (2008) [E3] DOI: 10.1111/j.1440-1843.2008.01252.x Co-authors: JODIE SIMPSON | ||
| 2008 | Hsu A, Hansbro PM, Wark PA, 'Innate immune response of bronchial epithelial cells to human and avian influenza virus', The 4th Congress of the Federation of Immunology Societies of Asia-Oceania: Conference Program, Taipei, Taiwan (2008) [E3] Co-authors: ALAN HSU, PHILIP HANSBRO | ||
| 2008 | Hsu A, Grissell TV, Wark PA, 'Distribution of SAa2,6GAL and SAa2,3GAL linked receptors in human respiratory tract and influenza virus replication', Respirology, Melbourne, VIC (2008) [E3] DOI: 10.1111/j.1440-1843.2008.01252_13.x Co-authors: ALAN HSU | ||
| 2008 | Wark PA, Davies BL, Parsons KS, Grissell T, 'Impaired release of inflammatory mediators from COPD bronchial epithelial cells (BECs) in response to rhinovirus (RV) and lipopolysaccharide (LPS)', Respirology, Melbourne, VIC (2008) [E3] | ||
| 2008 | Osei-Kumah A, Wark PA, Smith R, Ammit A, Clifton VL, 'A model of pregnancy induced changes in asthma', 51st Annual Scientific Meeting of the Endocrine Society of Australia and Society of Reproductive Biology: Meeting Proceedings and Abstract Book, Melbourne, VIC (2008) [E3] Co-authors: ROGER SMITH, vicki clifton | ||
| 2007 | Wark PA, Mimica J, Oldham R, Davies DE, Holgate SE, Johnston S, Gibson PG, 'Interferon-G induced protein (IP)- 10 is a novel clinical biomarker of rhinovirus (RV)-induced asthma exacerbations', Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3] Co-authors: PETER GIBSON | ||
| 2007 | Wark PA, Grissell TV, Davies B, Mimica J, Oldham R, Shafren DR, Gibson PG, 'Bronchial epithelial cell (BEC) response to clinical rhinovirus (clin-RV) isolates from ASTHMATICS compared to laboratory (lab-RV) strains', American Journal of Respiratory and Critical Care Medicine (American Thoracic Society 2007 International Conference Abstracts), San Francisco (2007) [E3] Co-authors: DARREN SHAFREN, PETER GIBSON | ||
| 2007 | Wark PA, See HV, Oldham R, Timmins N, Gibson PG, Hansbro PM, 'Response by peripheral blood monocytes (PBMCs) to rhinovirus (RV) is greater in cells exposed to infected epithelium in coculture than exposed to RV alone', American Journal of Respiratory and Critical Care Medicine (American Thoracic Society 2007 International Conference Abstracts), San Francisco (2007) [E3] Co-authors: PETER GIBSON, PHILIP HANSBRO | ||
| 2007 | Xatzipsalti M, Haynes R, Ribbene A, Sones JL, Bagmane D, Wark PA, et al., 'Deficient interferon production following rhinovirus infection of differentiated bronchial epithelial cells from asthmatic subjects', American Journal of Respiratory and Critical Care Medicine (American Thoracic Society 2007 International Conference Abstracts), San Francisco (2007) [E3] | ||
| 2007 | Jenkins CR, Marks GB, Gibson PG, Wark PA, Thien FCK, Belousova EG, et al., 'A randomised controlled trial of two algorithms for maintaining asthma control on long acting bronchodilators (LABA) and inhaled corticosteroids (ICS)', Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3] Co-authors: PETER GIBSON | ||
| 2007 | Saedi Some Olia A, Garg ML, Wood LG, Wark PA, Gibson PG, 'Lycopene enrichment of cultured epithelial airway cells', Asia Pacific Journal of Clinical Nutrition, Auckland, New Zealand (2007) [E3] Co-authors: LISA WOOD, MANOHAR GARG, PETER GIBSON | ||
| 2007 | Saedi Some Olia A, Garg ML, Wood LG, Gibson PG, Wark PA, 'Anti-inflammatory effect of lycopene enrichment on infected cultured airway epithelial cells', Respirology (Abstracts of the 12th Congress of the Asian Pacific Society of Respirology), Gold Coast, QLD (2007) [E3] Co-authors: LISA WOOD, MANOHAR GARG, PETER GIBSON | ||
| 2007 | De Groot RS, Kuo C, King N, Moir L, Lim S, Burgess JK, et al., 'Steroids can reverse rhinovirus-induced alterations to bronchial epithhelium extracellular matrix deposition', Respirology (Abstracts of the 12th Congress of the Asian Pacific Society of Respirology), Gold Coast, QLD (2007) [E3] | ||
| 2007 | Reddel HK, Peters MJ, Wark PA, Sand IB, Jenkins CR, 'Comparison of the efficacy of seretide and flixotide when down-titrating the inhaled corticosteroid dose', American Journal of Respiratory and Critical Care Medicine (American Thoracic Society 2007 International Conference Abstracts), San Francisco (2007) [E3] | ||
| 2007 | Ribbene A, Bucchieri F, Wark PA, Andrews AL, Puddicombe SM, Zummo G, et al., 'Epithelial-mesenchymal communication following rhinovirus infection of asthmatic bronchial epithelial cells', American Journal of Respiratory and Critical Care Medicine (American Thoracic Society 2007 International Conference Abstracts), San Francisco (2007) [E3] | ||
| 2007 | See H, Oldham R, Timmins N, Hansbro PM, Wark PA, Gibson PG, 'Rhinovirus (RV) induced inflammatory response in mononuclear cells is enhanced by coculture with airway epithelium', Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3] DOI: 10.1111/j.1440-1843.2007.001050.x Co-authors: PETER GIBSON, PHILIP HANSBRO | ||
| 2007 | Grissell TV, Hansbro NG, Hsu A, Mimica J, Wark PA, 'Response of primary bronchoepithelial cells from COPD, asthmatic and healthy subjects to infection with avian and human influenza virus strains', Respirology (Abstracts of the 12th Congress of the Asian Pacific Society of Respirology), Gold Coast, QLD (2007) [E3] Co-authors: NICOLE HANSBRO | ||
| 2006 | Wark PA, Wood LG, Grissell TV, Davies B, Shafren DR, Powell HG, et al., 'Acute virus-induced asthma is characterised by increased expression of toll-like receptors (TLR)-2', Respirology, Canberra (2006) [E3] Co-authors: DARREN SHAFREN, LISA WOOD, PETER GIBSON, michael hensley | ||
| 2006 | Grissell TV, Davies B, Mimica JL, Shafren DR, Gibson PG, Wark PA, 'Bronchial epithelial cell response to clinical rhinoviruses isolated from asthmatics compared to laboratory rhinovirus strains', Respirology, Canberra (2006) [E3] Co-authors: DARREN SHAFREN, PETER GIBSON | ||
| Show 76 more | |||
Creative Work (1 outputs)
| Year | Citation | Altmetrics | Link |
|---|---|---|---|
| 2011 | McDonald VM, Wark PA, Gibson PG, Alison J, Spencer L, Wood LG, Roberts M, Living with COPD: Chronic Obstructive Pulmonary Disease, The Australian Lung Foundation, Newcastle (2011) [J2] Co-authors: LISA WOOD, PETER GIBSON, VANESSA MCDONALD |
Grants and Funding
Summary
| Number of grants | 45 |
|---|---|
| Total funding | $10,914,759 |
Click on a grant title below to expand the full details for that specific grant.
2015 (2 grants)
Modifying epigenetics as a novel treatment in COPD$1,076,254
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Professor Phil Hansbro, Professor Darryl Knight, Conjoint Professor Peter Wark, Professor Ian Adcock | ||
| Scheme | Role | |
| Project Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $1,076,254 | 2015 | 2019 |
| GNo:G1400006 | ||
Enhanced oxidative stress impairs mitochondrial function and antiviral responses to rhinovirus infection in asthma and chronic obstructive pulmonary disease$25,222
Funding Body: John Hunter Hospital Charitable Trust Fund
| Project Team | ||
|---|---|---|
| Doctor Alan Hsu, Conjoint Professor Peter Wark, Miss Kristy Parsons | ||
| Scheme | Role | |
| Research Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $25,222 | 2015 | 2015 |
| GNo:G1500012 | ||
2014 (5 grants)
National Clinical Centre of Research Excellence in Severe Asthma$2,542,311
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Gibson, Professor Guy Marks, Associate Professor Vanessa McDonald, Conjoint Professor Peter Wark, Conjoint Associate Professor Greg King, Dr Bruce Thompson, Associate Professor Helen Reddel, Professor John Upham, Dr Lorraine Smith, Professor Alan James | ||
| Scheme | Role | |
| Centres of Research Excellence (CRE) - Centres of Clinical Research Excellence | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $2,542,311 | 2014 | 2019 |
| GNo:G1400017 | ||
Toll-like receptor 7 and asthma
$673,712
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Professor Joerg Mattes, Laureate Professor Paul Foster, Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Project Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $673,712 | 2014 | 2016 |
| GNo:G1300093 | ||
Mechanisms of dysregulated antiviral signallings to influenza infection in chronic obstructive pulmonary disease$27,512
Funding Body: John Hunter Hospital Charitable Trust Fund
| Project Team | ||
|---|---|---|
| Doctor Alan Hsu, Doctor Fatemeh Moheimani, Professor Darryl Knight, Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Research Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $27,512 | 2014 | 2014 |
| GNo:G1400435 | ||
Immunosenescence in chronic obstructive pulmonary disease leads to abnormal innate immune responses to human rhinovirus infection$20,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark, Professor Darryl Knight | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $20,000 | 2014 | 2014 |
| GNo:G1301331 | ||
Predicting who is at risk of worsening lung disease in Cystic Fibrosis$20,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark, Doctor Katie Baines, Associate Professor Vanessa McDonald, Conjoint Professor Peter Gibson, Associate Professor Scott Bell, Dr David Reid | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $20,000 | 2014 | 2014 |
| GNo:G1401410 | ||
2013 (5 grants)
Inflammometry in Stable COPD; A Randomised Controlled Trial (RCT)$717,071
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Gibson, Associate Professor Vanessa McDonald, Associate Professor Jodie Simpson, Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Project Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $717,071 | 2013 | 2016 |
| GNo:G1200185 | ||
Enhancing innate immune responses to influenza in chronic obstructive pulmonary disease$504,552
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark, Professor Phil Hansbro, Professor James Mahony | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $504,552 | 2013 | 2015 |
| GNo:G1200206 | ||
BD FACSCanto II Violet Laser (405nm) upgrade including Trigon and 2 photomultiplier tubes (PMTs)$25,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark, Doctor Alan Hsu, Doctor Katie Baines, Associate Professor Jodie Simpson, Conjoint Professor Peter Gibson, Ms Hayley See | ||
| Scheme | Role | |
| Equipment Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $25,000 | 2013 | 2013 |
| GNo:G1201180 | ||
Protecting Pregnant Women from Death during influenza epidemics$25,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Professor Roger Smith, Professor Phil Hansbro, Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Project Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $25,000 | 2013 | 2013 |
| GNo:G1301181 | ||
Mechanisms of impaired antiviral interferon response to influenza infection in primary bronchial epithelial cells from chronic obstructive pulmonary disease$23,810
Funding Body: John Hunter Hospital Charitable Trust Fund
| Project Team | ||
|---|---|---|
| Doctor Alan Hsu, Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Research Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $23,810 | 2013 | 2013 |
| GNo:G1300711 | ||
2012 (1 grants)
Body plethysmograph respiratory function system$33,076
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Gibson, Conjoint Professor Peter Wark, Associate Professor Lisa Wood, Associate Professor Jodie Simpson, Doctor Katie Baines, Doctor Vanessa Murphy, Doctor Jeffrey Pretto, Emeritus Professor Michael Hensley, Ms Jenny Mackney | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $33,076 | 2012 | 2012 |
| GNo:G1100973 | ||
2011 (7 grants)
Identifying new therapeutic targets for preventing the induction and progression of COPD$626,732
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Professor Phil Hansbro, Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Project Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $626,732 | 2011 | 2013 |
| GNo:G1000252 | ||
Role of Placental Retroviral Protein Syncytin Carried on Exosomes in Mediating Vulnerability of Pregnant Women to Influenza$622,968
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Professor Roger Smith, Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Project Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $622,968 | 2011 | 2013 |
| GNo:G1000294 | ||
Understanding the mechanisms of respiratory viral infection- and COPD-induced predisposition to secondary bacterial pneumonia
$573,390
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Professor Phil Hansbro, Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Project Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $573,390 | 2011 | 2013 |
| GNo:G1000248 | ||
Research microscope, confocal ready nikon eclipse 90i microscope$69,157
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Professor Roger Smith, Conjoint Professor Tam Zakar, Professor Jon Hirst, Doctor Kaushik Maiti, Doctor Gemma Madsen, Professor Rodney Scott, Conjoint Professor Peter Wark, Laureate Professor Paul Foster, Professor Phil Hansbro, Conjoint Professor Ian Wright | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $69,157 | 2011 | 2011 |
| GNo:G1100024 | ||
SCIREQ FlexiVentFX system + FlexiVentFX extension$45,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Professor Phil Hansbro, Laureate Professor Paul Foster, Professor Joerg Mattes, Doctor Simon Keely, Doctor Jay Horvat, Doctor Nicole Hansbro, Doctor Ming Yang, Doctor Catherine Ptaschinski, Doctor Kelly Asquith, Doctor Gough Au, Conjoint Professor Peter Wark, Laureate Professor John Aitken, Conjoint Professor Keith Jones, Professor Roger Smith, Professor Judith Black, Professor Rakesh Kumar, Professor Paul Hertzog | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $45,000 | 2011 | 2011 |
| GNo:G1100037 | ||
To determine if asthmatics and children at risk of asthma that develop acute exacerbations have defective antiviral innate immune responses$28,000
Funding Body: John Hunter Hospital Charitable Trust Fund
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark, Doctor Larry Roddick, Associate Professor Lisa Wood | ||
| Scheme | Role | |
| Research Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $28,000 | 2011 | 2011 |
| GNo:G1100177 | ||
Lung Function (Spirometry) testing and sputum induction equipment - establishing 3 new clinical workstations. Medgraphics CPFS/d USB spirometer with breezesuite software (x3). Laptop computer (x3). Ul$10,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Doctor Katie Baines, Conjoint Professor Peter Wark, Doctor Vanessa Murphy | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $10,000 | 2011 | 2011 |
| GNo:G1100038 | ||
2010 (2 grants)
Real time PCR machine (Mastercycler ep realplex2 from Epprndorf)
$34,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Associate Professor Jodie Simpson, Conjoint Professor Peter Gibson, Conjoint Professor Peter Wark, Associate Professor Lisa Wood, Doctor Vanessa Murphy, Doctor Robert Scott, Doctor Katie Baines | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $34,000 | 2010 | 2010 |
| GNo:G1000056 | ||
Identifying novel biomarkers of oxidative stress in chronic obstructive pulmonary disease$25,000
Funding Body: Hunter Children`s Research Foundation
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark, Associate Professor Lisa Wood | ||
| Scheme | Role | |
| Research Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $25,000 | 2010 | 2010 |
| GNo:G0900145 | ||
2009 (3 grants)
394591 ELx405UV select plate washer and workstation integration kit$27,500
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Gibson, Doctor Xiao Yan He, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $27,500 | 2009 | 2009 |
| GNo:G0189853 | ||
Development of novel therapeutic approaches for rhinovirus - induced asthma exacerbation$24,500
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Professor Joerg Mattes, Laureate Professor Paul Foster, Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Project Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $24,500 | 2009 | 2009 |
| GNo:G0189800 | ||
Treatment of subjects with cystic fibrosis who are colonised with aspergillus fumigatus$20,000
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark, Associate Professor Scott Bell, Associate Professor Peter Bye, Associate Professor Adam Jaffe, Dr Hiran Selvadurai, Professor Phillip Robinson | ||
| Scheme | Role | |
| Near Miss Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $20,000 | 2009 | 2009 |
| GNo:G0189818 | ||
2008 (6 grants)
Inflammatory mechanisms of airways disease$845,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $845,000 | 2008 | 2013 |
| GNo:G0189566 | ||
The mechanisms of infection of bronchial epithelial cells by human & avian influenza viruses in chronic airways disease$379,650
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark, Professor Phil Hansbro, Dr Ian Barr | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $379,650 | 2008 | 2010 |
| GNo:G0187593 | ||
The use of the components of the bacteria, streptococcus pneumoniae, as novel immunotherapies for asthma$50,000
Funding Body: Asthma Foundation of New South Wales
| Project Team | ||
|---|---|---|
| Professor Phil Hansbro, Professor Rakesh Kumar, Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Research Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $50,000 | 2008 | 2008 |
| GNo:G0188434 | ||
Mechanisms of inflammatory airways disease$40,571
Funding Body: Markey Insurance
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| HMRI Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $40,571 | 2008 | 2008 |
| GNo:G0189370 | ||
Becton Dickinson high throughout sampler for the FACSCanto II cytometry system$35,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Associate Professor Lisa Wood, Doctor Vanessa Murphy, Professor Phil Hansbro | ||
| Scheme | Role | |
| Equipment Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $35,000 | 2008 | 2008 |
| GNo:G0188547 | ||
PP2A: A new target for asthma therapy$20,000
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Professor Alistair Sim, Doctor Nikki Verrills, Professor John Scott, Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Near Miss Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $20,000 | 2008 | 2008 |
| GNo:G0188395 | ||
2007 (8 grants)
Chronic Exposure of Bronchial Epithelial Cells to Bacterial Components Modifies their Innate Immune Response to Infection with Respiratory Viruses$313,500
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $313,500 | 2007 | 2009 |
| GNo:G0186439 | ||
In vitro response of bronchial epithelial cells and activation of lymphocytes to infection with rhinovirus$58,848
Funding Body: John Hunter Hospital Charitable Trust Fund
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark, Professor Phil Hansbro, Associate Professor Jodie Simpson | ||
| Scheme | Role | |
| Research Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $58,848 | 2007 | 2009 |
| GNo:G0188095 | ||
Differential regulation of human mast cell degranulation by discrete forms of protein phosphatase 2A$50,000
Funding Body: Asthma Foundation of New South Wales
| Project Team | ||
|---|---|---|
| Professor Alistair Sim, Doctor Nikki Verrills, Laureate Professor Paul Foster, Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Dr Gregory Kranias | ||
| Scheme | Role | |
| Research Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $50,000 | 2007 | 2007 |
| GNo:G0187247 | ||
Nitric Oxide Monitoring System (NIOX)$45,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Gibson, Conjoint Associate Professor Vicki Clifton, Conjoint Professor Warwick Giles, Emeritus Professor Michael Hensley, Doctor Vanessa Murphy, Conjoint Professor Peter Wark, Associate Professor Vanessa McDonald, Associate Professor Jodie Simpson, Conjoint Associate Professor Bruce Whitehead, Laureate Professor Paul Foster, Professor Phil Hansbro, Associate Professor Lisa Wood | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $45,000 | 2007 | 2007 |
| GNo:G0188193 | ||
In vitro response of bronchial epithelial cells and activation of lymphocytes from COPD patients by infection with rhinovirus, respiratory syncytial virus and haemophilus influenza$25,000
Funding Body: GlaxoSmithKline Australia
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark, Professor Phil Hansbro, Associate Professor Jodie Simpson | ||
| Scheme | Role | |
| Support Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $25,000 | 2007 | 2008 |
| GNo:G0188309 | ||
Class II biohazard containment hood and carbon dioxide cell culture incubator$20,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Doctor Vanessa Murphy, Associate Professor Lisa Wood, Laureate Professor Paul Foster, Professor Phil Hansbro | ||
| Scheme | Role | |
| Equipment Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $20,000 | 2007 | 2007 |
| GNo:G0188192 | ||
Hewlett Packard 7890 series gas chromatograph with accessories$20,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Associate Professor Lisa Wood, Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Associate Professor Jodie Simpson, Doctor Vanessa Murphy, Laureate Professor Paul Foster, Professor Phil Hansbro, Conjoint Associate Professor Vicki Clifton, Professor Clare Collins, Conjoint Professor Wayne Smith, Professor John Attia | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $20,000 | 2007 | 2007 |
| GNo:G0188191 | ||
Miccroarrays to identify novel therapeutic targets for bird flu$14,500
Funding Body: John Hunter Hospital Charitable Trust Fund
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark, Professor Phil Hansbro | ||
| Scheme | Role | |
| Research Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $14,500 | 2007 | 2007 |
| GNo:G0187337 | ||
2006 (4 grants)
PRC Priority Research Centre for Asthma & Respiratory Diseases$524,282
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Laureate Professor Paul Foster, Conjoint Professor Peter Gibson, Conjoint Professor Kenneth Beagley, Emeritus Professor Michael Hensley, Professor Phil Hansbro, Professor Joerg Mattes, Professor Alistair Sim, Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Priority Research Centre | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $524,282 | 2006 | 2013 |
| GNo:G0186914 | ||
Surveillance and Analysis of Avian Influenza Viruses in Migratory Birds in Australia$249,625
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Professor Phil Hansbro, Dr Ian Barr, Conjoint Professor Peter Wark, Dr Paul Selleck, Dr Simone Warner, Laureate Professor Paul Foster, Dr Aeron Hurt, Dr Irene Peroulis, Dr John Curran, Conjoint Professor Peter Gibson | ||
| Scheme | Role | |
| Potential Avian Influenza-Induced Pandemic | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $249,625 | 2006 | 2006 |
| GNo:G0186000 | ||
The interaction between airway epithelial cells infected with rhinovirus and lymphocytes from subjects with COPD$15,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $15,000 | 2006 | 2006 |
| GNo:G0186106 | ||
Equipment - Microscope$5,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| PULSE Early Career Researcher of the Year Award | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $5,000 | 2006 | 2006 |
| GNo:G0186168 | ||
2001 (1 grants)
Mechanisms of bronchial epithelial cell activation in rhinovirus infection in asthma, COAD and normal airways$338,516
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Training (Postdoctoral) Fellowships - Neil Hamilton Fairley Clinical Fellowship (Overseas) | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $338,516 | 2001 | 2005 |
| GNo:G0180753 | ||
1998 (1 grants)
The investigation of airway inflammation and cell death in acute severe asthma$45,500
Funding Body: Asthma Foundation of New South Wales
| Project Team | ||
|---|---|---|
| Conjoint Professor Peter Gibson, Conjoint Professor Peter Wark | ||
| Scheme | Role | |
| Research Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $45,500 | 1998 | 1999 |
| GNo:G0177660 | ||
Research Supervision
| Number of current supervisions | 7 |
|---|---|
| Total current UoN PhD EFTSL | 1.55 |
For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.
Current Supervision
| Commenced | Proposed Completion | Program | Supervisor Type | Research Title |
|---|---|---|---|---|
| 2015 | 2017 | PhD (Immunology & Microbiol) | Co-Supervisor | Contribution of Cell Death to the Pathogenesis of Chronic Obstructive Pulmonary Disease (COPD) |
| 2014 | 2018 | PhD (Immunology & Microbiol) | Co-Supervisor | Chronic Obstructive Pulmonary Disease (COPD) |
| 2013 | 2017 | PhD (Medicine) | Principal Supervisor | The Role of the PI3K Signalling Pathway in the Innate Antiviral Response of Airway Epithelial Cells |
| 2013 | 2017 | PhD (Immunology & Microbiol) | Co-Supervisor | Investigation of the pathogenesis and potential therapeutic interventions of influenza in Asthma and COPD |
| 2011 | 2015 | PhD (Medicine) | Principal Supervisor | Oxidative Stress Impairs Mitochondrial Function in Healthy and Asthmatic Primary Bronchial Epithelial Cells |
| 2010 | 2015 | PhD (Immunology & Microbiol) | Co-Supervisor | Indentification of New Therapeutics in COPD/ Emphysema |
| 2009 | 2013 | PhD (Immunology & Microbiol) | Co-Supervisor | Mechanisms of Increased Susceptibility to Influenza Infection in Mouse Models of Chronic Lung Disease |
Past Supervision
| Year | Program | Supervisor Type | Research Title |
|---|---|---|---|
| 2015 | PhD (Medicine) | Principal Supervisor | Characterising Innate Immune Responses and the Role of PD-1 in Patients with COPD |
| 2014 | PhD (Medical Biochemistry) | Co-Supervisor | Role of Antioxidants in Rhinovirus-Infected Airway Epithelial Cells |
| 2013 | M Philosophy (Medicine) | Co-Supervisor | An Investigation of Body Composition in People With and Without Chronic Obstructive Pulmonary Disease (COPD) |
| 2013 | PhD (Medicine) | Co-Supervisor | Investigation of the Immune Mechanisms in Pregnancy and Asthma Leading to Increased Susceptibility and Disease Severity to Respiratory Virus Infections |
| 2011 | PhD (Immunology & Microbiol) | Co-Supervisor | Immune Mechanisms that Promote the Development of Inducible Bronchus-Associated Lymphoid Tissue (IBALT) |
| 2010 | PhD (Medicine) | Principal Supervisor | Mechanism of Infection of Bronchial Epithelial Cells by Human and Avian Influenza Viruses |
Conjoint Professor Peter Wark
| Work Phone | (02) 40420110 |
|---|---|
| Fax | (02) 4985 5850 |
| Peter.Wark@newcastle.edu.au | |
| Position | Conjoint Professor Centre for Asthma and Respiratory Disease School of Medicine and Public Health Faculty of Health and Medicine |
| Focus Area | Immunology and Microbiology |
| Office | 2107, Level 2, West HMRI building, Lot 1 Kookaburra Close New Lambton |
| URL: | www.newcastle.edu.au/profile/peter-wark |
