
Dr Steve Smith
Conjoint Associate Professor
School of Medicine and Public Health
Career Summary
Biography
I am a colorectal surgeon at John Hunter Hospital and a Conjoint Associate Professor, University of Newcastle with an interest in improving the peri-operative management of surgical patients particularly with regards to surgical oncology.
In keeping with this I have completed a Bachelor of Science (UNSW), a Bachelor of Medicine and Surgery (UNSW), a Fellowship in Surgery (FRACS), a Fellowship in Colorectal Surgery (CSSANZ), a Masters in Surgery (USyd) and a Doctor of Philosophy (UoN). The bulk of my research is in the form of randomised clinical trials designed to enhance the recovery of patients undergoing surgery (particularly colorectal surgery for cancer).
I also have a keen interest in surgical education and have been the Network Director of Surgical Training for the Hunter New England region since 2010.
My current research projects include:
The Newcastle Skin Prep Trial (an RCT of 3300 patients designed to assess the best form of antiseptic skin preparation prior to surgery)
The PREDICT study (a prospective international multi-centre study, n=900, assessing the role of CRP in predicting colorectal anastomotic leakage)
The CAPS study (an early phase study on the role of cannabinoids for gastrointestinal surgical recovery)
The VET study (pilot study looking at VTE prophylaxis for major surgery)
The PIMCO study (assessing inflammatory mediators in colorectal cancer and their role in recurrence)
The DiCRePiT study (CRP trajectory in acute diverticulitis)
A prospective study assessing wound and gut microbiome in patients with colorectal cancer undergoing surgery
Assessing the use of vacuum dressings on contaminated wounds
Assessing the role of humidified CO2 in colorectal anastomotic healing
Keywords
- Colorectal Cancer
- Colorectal Surgery
- ERAS - Enhanced Recovery After Surgery
- Surgical Clinical Trials
- Surgical Training
Awards
Prize
Year | Award |
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2019 |
Hunter Medical Research Institute Award for Early Career Researcher Hunter Medical Research Institute (HMRI) |
Professional
Year | Award |
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2013 |
Royal Australasian College of Surgeons/American College of Surgeons Travelling Fellow Royal Australasian College of Surgeons (RACS) |
Grant Reviews
Year | Grant | Amount |
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2019 |
Clinical Trials and Cohort Studies C1100 - Aust Competitive - NHMRC - 1100, C1100 - Aust Competitive - NHMRC - 1100 |
$70,000,000 |
Publications
For publications that are currently unpublished or in-press, details are shown in italics.
Journal article (35 outputs)
Year | Citation | Altmetrics | Link | ||||||||
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2020 |
Stephensen BD, Reid F, Shaikh S, Carroll R, Smith SR, Pockney P, 'C-reactive protein trajectory to predict colorectal anastomotic leak: PREDICT Study', British Journal of Surgery, 107 1832-1837 (2020)
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2020 |
Storey B, Smith S, Bateman G, McLeod N, 'Unusual cause for recurrent epididymo-orchitis: fistula from rectal stump to seminal vesicle', ANZ JOURNAL OF SURGERY, 90 164-166 (2020)
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2020 |
Zhao J, Peters L, Gelzinnis S, Carroll R, Nolan J, Di Sano S, et al., 'Post-discharge opioid prescribing after laparoscopic appendicectomy and cholecystectomy', ANZ Journal of Surgery, 90 1014-1018 (2020) © 2020 Royal Australasian College of Surgeons Background: Opioid over-prescription following surgery is a significant public health issue in most developed countries. Multiple stu... [more] © 2020 Royal Australasian College of Surgeons Background: Opioid over-prescription following surgery is a significant public health issue in most developed countries. Multiple studies have been conducted in the USA demonstrating and investigating the issue; however, there is a lack of literature addressing this topic in the Australian setting. The aim of this study is to review prescribing practices at an Australian tertiary referral hospital on discharge in patients having undergone laparoscopic cholecystectomy (LC) or laparoscopic appendicetomy (LA). Additionally, to identify potential factors which influence medical officer prescribing practices. Methods: A retrospective observational study on opioid prescribing practice on all patients who underwent LC or LA over a 12-month period at an Australian tertiary referral hospital. Results: A total of 435 patients (223 LC, 214 LA) were prescribed a mean opioid dose on discharge of 25 oral morphine milli-equivalents (range 0¿180 morphine milli-equivalents). Less opioids were prescribed following elective procedures (42% versus 10%, P < 0.001). There is a downward trend of opioid prescribing on discharge as the Junior Medical Officer clinical year progresses (P < 0.001). Conclusions: This study demonstrates a lower rate of opiate prescription on discharge for LC and LA in an Australian setting when compared to the US data. There is a wide diversity of prescribing demonstrated. This indicates the need for better training of opioid prescribers to reduce over-prescribing.
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2020 |
Carroll GM, Burns GL, Petit JA, Walker MM, Mathe A, Smith SR, et al., 'Does postoperative inflammation or sepsis generate neutrophil extracellular traps that influence colorectal cancer progression? A systematic review', Surgery Open Science, 2 57-69 (2020) [C1]
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2020 |
Storey B, Zhao J, Chern T, Petersson J, Smith S, 'How to do it: single-dermatome single-incision laparoscopic right hemicolectomy', ANZ Journal of Surgery, (2020)
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2020 |
Peters LE, Zhao J, Martin J, Smith SR, Pockney P, 'Comment on "Opioids After Surgery in the United States Versus the Rest of the World: The International Patterns of Opioid Prescribing (iPOP) Multicenter Study".', Ann Surg, Publish Ahead of Print (2020)
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2019 |
Stephensen BD, Clarke L, McManus B, Clark S, Carroll R, Holz P, Smith SR, 'The LAPLAP study: a randomized placebo-controlled clinical trial assessing postoperative functional recovery using intraperitoneal local anaesthetic in laparoscopic colorectal surgery', Colorectal Disease, 21 1183-1191 (2019) [C1] Colorectal Disease © 2019 The Association of Coloproctology of Great Britain and Ireland Aim: Postoperative pain remains a major factor in recovery from colorectal resection. Ther... [more] Colorectal Disease © 2019 The Association of Coloproctology of Great Britain and Ireland Aim: Postoperative pain remains a major factor in recovery from colorectal resection. There is increasing interest in opioid-sparing analgesia, and intraperitoneal local anaesthetic (IPLA) has recently been shown to be useful in minor laparoscopic and open colorectal procedures. The aim of this study was to evaluate the impact of IPLA on functional recovery following major laparoscopic surgery. In this controlled trial, mobility, as measured by the De Morton Mobility Index (DEMMI), was used as a surrogate for postoperative functional recovery. Method: Patients undergoing laparoscopic colorectal resection were randomized either to continuous ropivacaine (0.2% at 4¿6¿ml/h) or to saline (0.9%) which were administered via intraperitoneal catheter for 3¿days postoperatively. Results were analysed in a double-blind manner. DEMMIs were assessed on postoperative days 1, 2, 3, 7 and 30, and data on pain, opioid consumption, gut and respiratory function, length of stay (LOS) and complications were recorded. Results: Ninety-six patients were recruited. There was no difference in primary outcome (i.e., functional recovery) between IPLA and placebo groups. Opioid consumption and LOS were similar between groups, and no differences were found for any secondary outcome measure. There were no adverse events related to ropivacaine. Conclusion: Infusional intraperitoneal local anaesthetic appears to be safe but does not improve functional recovery or analgesic consumption following elective laparoscopic colorectal surgery, in the setting of an established enhanced recovery programme.
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2018 |
Smith SR, Murray D, Pockney PG, Bendinelli C, Draganic BD, Carroll R, 'Tranexamic Acid for Lower GI Hemorrhage: A Randomized Placebo-Controlled Clinical Trial', Diseases of the Colon and Rectum, 61 99-106 (2018) [C1] © 2017 The American Society of Colon and Rectal Surgeons, Inc. BACKGROUND: Lower GI hemorrhage is a common source of morbidity and mortality. Tranexamic acid is an antifibrinolyti... [more] © 2017 The American Society of Colon and Rectal Surgeons, Inc. BACKGROUND: Lower GI hemorrhage is a common source of morbidity and mortality. Tranexamic acid is an antifibrinolytic that has been shown to reduce blood loss in a variety of clinical conditions. Information regarding the use of tranexamic acid in treating lower GI hemorrhage is lacking. OBJECTIVE: The aim of this trial was to determine the clinical efficacy of tranexamic acid when used for lower GI hemorrhage. DESIGN: This was a prospective, double-blind, placebo-controlled, randomized clinical trial. SETTINGS: The study was conducted at a tertiary referral university hospital in Australia. PATIENTS: Consecutive patients aged >18 years with lower GI hemorrhage requiring hospital admission from November 2011 to January 2014 were screened for trial eligibility (N = 265). INTERVENTIONS: A total of 100 patients were recruited after exclusions and were randomly assigned 1:1 to either tranexamic acid or placebo. MAIN OUTCOME MEASURES: The primary outcome was blood loss as determined by reduction in hemoglobin levels. The secondary outcomes were transfusion rates, transfusion volume, intervention rates for bleeding, length of hospital stay, readmission, and complication rates. RESULTS: There was no difference between groups with respect to hemoglobin drop (11 g/L of tranexamic acid vs 13 g/L of placebo; p = 0.9445). There was no difference with respect to transfusion rates (14/49 tranexamic acid vs 16/47 placebo; p = 0.661), mean transfusion volume (1.27 vs 1.93 units; p = 0.355), intervention rates (7/49 vs 13/47; p = 0.134), length of hospital stay (4.67 vs 4.74 d; p = 0.934), readmission, or complication rates. No complications occurred as a direct result of tranexamic acid use. LIMITATIONS: A larger multicenter trial may be required to determine whether there are more subtle advantages with tranexamic acid use in some of the secondary outcomes. CONCLUSIONS: Tranexamic acid does not appear to decrease blood loss or improve clinical outcomes in patients presenting with lower GI hemorrhage in the context of this trial. see Video Abstract at http://links.lww.com/DCR/A453.
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2018 |
Carroll GM, Hampton J, Carroll R, Smith SR, 'Mobility scores as a predictor of length of stay in general surgery: a prospective cohort study', ANZ Journal of Surgery, 88 860-864 (2018) [C1] © 2018 Royal Australasian College of Surgeons Background: Post-operative length of stay (LOS) is an increasingly important clinical indicator in general surgery. Despite this, no ... [more] © 2018 Royal Australasian College of Surgeons Background: Post-operative length of stay (LOS) is an increasingly important clinical indicator in general surgery. Despite this, no tool has been validated to predict LOS or readiness for discharge in general surgical patients. The de Morton Mobility Index (DEMMI) is a functional mobility assessment tool that has been validated in rehabilitation patient populations. In this prospective cohort study, we aimed to identify if trends in DEMMI scores were associated with discharge within 1 week and overall LOS in general surgical patients. Methods: A total of 161 patients who underwent elective gastrointestinal resections were included. DEMMI scores were performed preoperatively, on days 1, 2, 3 and 30 post-operative. Statistical analysis was performed to identify any association between DEMMI scores and discharge within 1 week and LOS. Results: Functional recovery (measured by achieving 80% of baseline DEMMI score by post-operative day 1) was significantly associated with discharge within 1 week. Presence of a stoma was associated with longer LOS. The area under the receiver operating characteristic curve using functional recovery on post-operative day 1 as a predictor of discharge within 1 week is 0.772. Conclusion: The DEMMI score is a fast, easy and useful tool to, on post-operative day 1, predict discharge within 1 week. The utility of this is to act as an anticipatory trigger for more proactive and efficient discharge planning in the early post-operative period, and there is potential to use the DEMMI as a comparator in clinical trials to assess functional recovery.
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2018 |
Roberts ST, Patel K, Smith SR, 'Impact of avoiding post-operative urinary catheters on outcomes following colorectal resection in an ERAS programme: No IDUC and ERAS programmes', ANZ Journal of Surgery, 88 E390-E394 (2018) [C1]
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2018 |
Smith SR, Pockney P, Holmes R, Doig F, Attia J, Holliday E, et al., 'Biomarkers and anastomotic leakage in colorectal surgery: C-reactive protein trajectory is the gold standard.', ANZ journal of surgery, 88 440-444 (2018) [C1]
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2018 |
Holmes R, Smith SR, Carroll R, Holz P, Mehrotra R, Pockney P, 'Randomized clinical trial to assess the ideal mode of delivery for local anaesthetic abdominal wall blocks.', ANZ journal of surgery, 88 786-791 (2018) [C1]
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2017 |
Penna M, Hompes R, Arnold S, Wynn G, Austin R, Warusavitarne J, et al., 'Transanal Total Mesorectal Excision: International Registry Results of the First 720 Cases', Annals of Surgery, 266 111-117 (2017) [C1] Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. Objective: This study aims to report short-term clinical and oncological outcomes from the international transana... [more] Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. Objective: This study aims to report short-term clinical and oncological outcomes from the international transanal Total Mesorectal Excision (taTME) registry for benign and malignant rectal pathology. Background: TaTME is the latest minimally invasive transanal technique pioneered to facilitate difficult pelvic dissections. Outcomes have been published from small cohorts, but larger series can further assess the safety and efficacy of taTME in the wider surgical population. Methods: Data were analyzed from 66 registered units in 23 countries. The primary endpoint was "good-quality TME surgery." Secondary endpoints were short-term adverse events. Univariate and multivariate regression analyses were used to identify independent predictors of poor specimen outcome. Results: A total of 720 consecutively registered cases were analyzed comprising 634 patients with rectal cancer and 86 with benign pathology. Approximately, 67% were males with mean BMI 26.5 kg/m 2. Abdominal or perineal conversion was 6.3% and 2.8%, respectively. Intact TME specimens were achieved in 85%, with minor defects in 11% and major defects in 4%. R1 resection rate was 2.7%. Postoperative mortality and morbidity were 0.5% and 32.6% respectively. Risk factors for poor specimen outcome (suboptimal TME specimen, perforation, and/or R1 resection) on multivariate analysis were positive CRM on staging MRI, low rectal tumor <2 cm from anorectal junction, and laparoscopic transabdominal posterior dissection to <4 cm from anal verge. Conclusions: TaTME appears to be an oncologically safe and effective technique for distal mesorectal dissection with acceptable short-term patient outcomes and good specimen quality. Ongoing structured training and the upcoming randomized controlled trials are needed to assess the technique further.
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2017 |
Schmiegel W, Scott RJ, Dooley S, Lewis W, Meldrum CJ, Pockney P, et al., 'Blood-based detection of RAS mutations to guide anti-EGFR therapy in colorectal cancer patients: concordance of results from circulating tumor DNA and tissue-based RAS testing', MOLECULAR ONCOLOGY, 11 208-219 (2017) [C1]
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2015 |
Smith S, Pockney P, Attia J, 'Corrigendum: A Meta-analysis on the Effect of Sham Feeding Following Colectomy: Should Gum Chewing Be Included in Enhanced Recovery After Surgery Protocols?', Diseases of the colon and rectum, 58 e416 (2015) [O1]
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2015 |
Smith SR, Draganic B, Pockney P, Holz P, Holmes R, Mcmanus B, Carroll R, 'Transversus abdominis plane blockade in laparoscopic colorectal surgery: a double-blind randomized clinical trial', INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 30 1237-1245 (2015) [C1]
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2014 |
Ho YM, Smith SR, Pockney P, Lim P, Attia J, 'A Meta-analysis on the Effect of Sham Feeding Following Colectomy: Should Gum Chewing Be Included in Enhanced Recovery After Surgery Protocols?', DISEASES OF THE COLON & RECTUM, 57 115-126 (2014) [C1]
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2014 |
Smith SR, 'The author replies', Diseases of the Colon and Rectum, 57 (2014)
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2014 |
Ho YM, Gani J, Draganic BD, Smith SR, 'Bladeless stoma creation using muscle separation technology: a novel technique', TECHNIQUES IN COLOPROCTOLOGY, 18 299-300 (2014) [C3]
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2013 |
Lim P, Morris OJ, Nolan G, Moore S, Draganic B, Smith SR, 'Sham Feeding With Chewing Gum After Elective Colorectal Resectional Surgery A Randomized Clinical Trial', ANNALS OF SURGERY, 257 1016-1024 (2013) [C1]
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2013 |
Young JM, Butow PN, Walsh J, Durcinoska I, Dobbins TA, Rodwell L, et al., 'Multicenter Randomized Trial of Centralized Nurse-Led Telephone-Based Care Coordination to Improve Outcomes After Surgical Resection for Colorectal Cancer: The CONNECT Intervention', JOURNAL OF CLINICAL ONCOLOGY, 31 3585-+ (2013)
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2013 |
Morris OJ, Smith S, Draganic B, 'Comparison of bulking agents in the treatment of fecal incontinence: A prospective randomized clinical trial', Techniques in Coloproctology, 17 517-523 (2013) [C1] Background: We sought to compare two synthetic injectable bulking agents, with known efficacy (PTQ¿: a silicone biomaterial and Durasphere ®: pyrolytic carbon-coated beads), in th... [more] Background: We sought to compare two synthetic injectable bulking agents, with known efficacy (PTQ¿: a silicone biomaterial and Durasphere ®: pyrolytic carbon-coated beads), in the form of a randomised clinical trial. Methods: Circumferential injection of either agent was performed under local anesthesia and sedation as a day-case procedure. The primary outcome measure was the Wexner incontinence scale. Secondary measures were the short-form 36 (SF-36) quality of life assessment and manometry (maximum resting and squeeze pressures). Follow-up was at 6 weeks, 6 and 12 months. Results: Thirty-five patients were randomised, 17 to PTQ® and 18 to Durasphere®. Early closure of the trial occurred, due to the removal of the agent PTQ®, from the Australian Pharmaceutical Benefits scheme. Wexner incontinence scores were significantly better than baseline, in both groups, at 6 weeks and 6 months (P < 0.05), although the improvements were not significant at 12 months. There was no significant improvement for either agent, from baseline, in mean SF-36 scores at any follow-up sessions. There was no significant difference between the two bulking agents, with regard to both Wexner and SF-36 scores, at any of the follow-up sessions. Complications occurred in one patient in the PTQ group (perianal abscess) and did not occur in any of the patients in the Durasphere group. Conclusions: This trial appears to show that both synthetic agents PTQ ® and Durasphere® are effective and safe, although long-term improvement is limited. In this trial, there appears to be no difference in efficacy between the two agents, over a 12-month follow-up period. © 2013 Springer-Verlag Italia.
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2012 |
Moore SE, Reid KC, Draganic B, Smith S, 'Randomized clinical trial of ropivacaine wound infusion following laparoscopic colorectal surgery', Techniques in Coloproctology, 16 431-436 (2012) [C1]
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2011 |
Smith S, 'Author's reply: Randomized clinical trial of short-term outcomes following purse-string versus conventional closure of ileostomy wounds (Br J Surg 2010; 97: 1511-1517)', British Journal of Surgery, 98 458 (2011) [C3]
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2011 |
Morris OJ, Draganic B, Smith S, 'Does a learning curve exist in endorectal two-dimensional ultrasound accuracy?', Techniques in Coloproctology, 15 301-311 (2011) [C1]
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2010 |
Reid K, Pockney P, Draganic B, Smith S, 'Barrier wound protection decreases surgical site infection in open elective colorectal surgery: A randomized clinical trial', Diseases of the Colon & Rectum, 53 1374-1380 (2010) [C1]
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2010 |
Smith S, Solomon M, 'Functional comparisons between open and laparoscopic rectopexy', Gastroenterologie Clinique Et Biologique, 34 505-507 (2010) [C3]
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Show 32 more journal articles |
Review (3 outputs)
Year | Citation | Altmetrics | Link | ||||||||
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2021 |
Reid FSW, Egoroff N, Pockney PG, Smith SR, 'A systematic scoping review on natural killer cell function in colorectal cancer.', Cancer Immunol Immunother (2021)
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2020 |
Makanyengo SO, Carroll GM, Goggins BJ, Smith SR, Pockney PG, Keely S, 'Systematic Review on the Influence of Tissue Oxygenation on Gut Microbiota and Anastomotic Healing.', J Surg Res (2020)
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Park SSW, Feng D, Smith S, 'A systematic review and meta-analysis comparing intracorporeal anastomosis and extracorporeal anastomosis in minimally invasive colectomies', Mini-invasive Surgery
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Conference (4 outputs)
Year | Citation | Altmetrics | Link | |||||
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2016 |
Smith SA, Roberts DJ, Lipson ME, Buie WD, Maclean AR, 'Postoperative nonsteroidal anti-inflammatory drug use and intestinal anastomotic dehiscence: A systematic review and meta-analysis', Diseases of the Colon and Rectum (2016) © The ASCRS 2016. BACKGROUND: Nonsteroidal anti-inflammatory drugs are commonly used analgesics in colorectal surgery. Controversy exists regarding the potential association betwe... [more] © The ASCRS 2016. BACKGROUND: Nonsteroidal anti-inflammatory drugs are commonly used analgesics in colorectal surgery. Controversy exists regarding the potential association between these drugs and anastomotic dehiscence. OBJECTIVE: This study aimed to determine whether postoperative nonsteroidal anti-inflammatory drug use is associated with intestinal anastomotic dehiscence. DATA SOURCES: PubMed, EMBASE, CENTRAL, and references of included articles were searched without date or language restriction. STUDY SELECTION: Randomized controlled trials and observational studies that compared postoperative nonsteroidal anti-inflammatory drug use with nonuse and reported on intestinal anastomotic dehiscence were selected. INTERVENTION: The use of postoperative nonsteroidal anti-inflammatory drugs relative to placebo or nonuse was investigated. MAIN OUTCOME MEASURES: Risk ratios and adjusted or unadjusted odds ratios for anastomotic dehiscence were pooled across randomized controlled trials and observational studies using DerSimonian and Laird random-effects models. RESULTS: Among 4395 citations identified, 6 randomized controlled trials (n = 473 patients) and 11 observational studies (n > 20,184 patients) were included. Pooled analyses revealed that nonsteroidal anti-inflammatory drug use was nonsignificantly associated with anastomotic dehiscence in randomized controlled trials (risk ratio, 1.96; 95% CI, 0.74-5.16; I 2 = 0%) and significantly associated with anastomotic dehiscence in observational studies (OR, 1.46; 95% CI, 1.14-1.86; I 2 = 54%). In stratified analyses of observational study data, the pooled OR for anastomotic dehiscence was statistically significant for studies of nonselective nonsteroidal anti-inflammatory drug use (6 studies; > 4900 patients; OR, 2.09; 95% CI, 1.65-2.64; I 2 = 0%), but was not statistically significant for studies of cyclooxygenase-2 selective nonsteroidal anti-inflammatory drug use (3 studies; >697 patients; OR, 1.34; 95% CI, 0.78-2.31; I 2 = 0%). LIMITATIONS: Studies varied by patient selection criteria, drug exposures, and definitions of anastomotic dehiscence. Analyses of randomized controlled trials and cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs were potentially underpowered. CONCLUSIONS: Pooled observational data suggest an association between postoperative nonsteroidal anti-inflammatory drug use and intestinal anastomotic dehiscence. Caution may be warranted in using these medications in patients at risk for this complication.
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2015 |
Scott R, Dooley S, Lewis W, Meldrum C, Pockney P, Draganic B, et al., 'Concordance of RAS mutation status in CRC patients by comparison of results from circulating tumour DNA and tissue-based testing', ANNALS OF ONCOLOGY, Barcelona, SPAIN (2015) [E3]
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2014 | Dargan J, Smith S, Smith JM, 'Lab based anatomical instruction for prevocational trainees needs assessment and pilot study', Pokolbin, NSW (2014) | |||||||
2013 |
Grice DM, Bauer DC, Duesing K, Li D, Greenfield P, Nielsen S, et al., 'Human and microbial transcriptomics from lean and obese individuals with colorectal cancer: A comparison of Total and Poly A RNA sequencing from clinical samples.', CANCER RESEARCH, Washington, DC (2013) [E3]
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Show 1 more conference |
Grants and Funding
Summary
Number of grants | 32 |
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Total funding | $11,407,070 |
Click on a grant title below to expand the full details for that specific grant.
20212 grants / $406,439
2021 HMRI MRSP - Cancer Program$286,439
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
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Project Team | Laureate Professor Rodney Scott, Laureate Professor Rodney Scott, Associate Professor Kelly Kiejda, Professor Amanda Baker, Doctor Michelle Bovill, Associate Professor Matt Dun, Doctor Anoop Enjeti, Doctor Liz Fradgley, Associate Professor Gillian Gould, Conjoint Professor Peter Greer, Professor Hubert Hondermarck, Associate Professor Lei Jin, Doctor Heather Lee, Conjoint Associate Professor Joerg Lehmann, Professor Christine Paul, Doctor Steve Smith, Professor Pradeep Tanwar, Associate Professor Nikki Verrills, Professor Xu Dong Zhang, Doctor Peter Pockney, Professor Adam McCluskey |
Scheme | NSW MRSP Infrastructure Grant |
Role | Investigator |
Funding Start | 2021 |
Funding Finish | 2021 |
GNo | G2001330 |
Type Of Funding | C2220 - Aust StateTerritoryLocal - Other |
Category | 2220 |
UON | Y |
Peri-operative factors affecting Natural Killer Cell function and their role in colorectal cancer re-occurrence and metastasis$120,000
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
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Project Team | Professor Simon Keely, Doctor Steve Smith, Joanne Soh |
Scheme | Research Grant |
Role | Investigator |
Funding Start | 2021 |
Funding Finish | 2024 |
GNo | G2001397 |
Type Of Funding | C3120 - Aust Philanthropy |
Category | 3120 |
UON | Y |
20205 grants / $378,444
MRSP Cancer 2020$299,193
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
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Project Team | Laureate Professor Rodney Scott, Associate Professor Nikki Verrills, Professor Christine Paul, Doctor Steve Smith, Doctor Jennette Sakoff, Doctor Jude Weidenhofer, Professor Billie Bonevski |
Scheme | NSW MRSP Infrastructure Grant |
Role | Investigator |
Funding Start | 2020 |
Funding Finish | 2021 |
GNo | G1901468 |
Type Of Funding | C2220 - Aust StateTerritoryLocal - Other |
Category | 2220 |
UON | Y |
Colorectal Surgical Society of Australia and New Zealand Foundation Pty Ltd$31,989
Funding body: Colorectal Surgical Society of Australia and New Zealand Foundation Pty Ltd
Funding body | Colorectal Surgical Society of Australia and New Zealand Foundation Pty Ltd |
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Project Team | Dr Steve Smith, Dr Brian Draganic, Dr Jie Zhao, Rosemary Carroll, Melissa Chaplin, Natalie Lott |
Scheme | Research Grant |
Role | Lead |
Funding Start | 2020 |
Funding Finish | 2022 |
GNo | |
Type Of Funding | C1700 - Aust Competitive - Other |
Category | 1700 |
UON | N |
NSW Regional Health Partners Health Economics Analysis of a Clinical Trial Results$17,500
Funding body: NSW Regional Health Partners
Funding body | NSW Regional Health Partners |
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Project Team | Dr Steve Smith, Simon Deeming, Dr Chris Oldmeadow, Professor Jonathan Gani, Professor Andrew Searle, Natalie Lott, Rosemary Carroll |
Scheme | Research Grant |
Role | Lead |
Funding Start | 2020 |
Funding Finish | 2021 |
GNo | |
Type Of Funding | C1600 - Aust Competitive - StateTerritory Govt |
Category | 1600 |
UON | N |
Hunter New England Research and Innovation Grant (co-funded with NSW RHP)$17,500
Funding body: Hunter New England Health LHD, NSW Health
Funding body | Hunter New England Health LHD, NSW Health |
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Project Team | Dr Steve Smith, Simon Deeming, Dr Chris Oldmeadow, Professor Jonathan Gani, Professor Andrew Searle, Natalie Lott, Rosemary Carroll |
Scheme | HNE Research and Development |
Role | Lead |
Funding Start | 2020 |
Funding Finish | 2021 |
GNo | |
Type Of Funding | C1600 - Aust Competitive - StateTerritory Govt |
Category | 1600 |
UON | N |
John Hunter Hospital Charitable Trust Grant$12,262
Funding body: John Hunter Charitable Trust Grant
Funding body | John Hunter Charitable Trust Grant |
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Project Team | Dr Steve Smith, Dr Kalpesh Shah, Professor Jennifer Martin, Dr Catherine Lucas, Rosemary Carroll, Natalie Lott, Dr Imogen Thomson, Dr Peter Galettis, Jasminka Sarunac |
Scheme | John Hunter Charitable Trust Grant |
Role | Lead |
Funding Start | 2020 |
Funding Finish | 2020 |
GNo | |
Type Of Funding | C1700 - Aust Competitive - Other |
Category | 1700 |
UON | N |
201911 grants / $839,812
Testing the impact of an Interactive Health Communication Application on days alive out of hospital and quality of life following surgery for colorectal cancer$303,019
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
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Project Team | Doctor Steve Smith, Laureate Professor Robert Sanson-Fisher, Dr Jon Gani, Conjoint Professor Jonathan Gani, Professor Mariko Carey, Sancha Robinson, Doctor Sancha Robinson, Conjoint Professor Andrew Searles, Professor Andrew Searles, Doctor Peter Pockney, Doctor Christopher Oldmeadow, Mr Chris Oldmeadow, Conjoint Associate Professor Ross Kerridge |
Scheme | Partnership Projects |
Role | Lead |
Funding Start | 2019 |
Funding Finish | 2025 |
GNo | G1800929 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
HMRI MRSP Infrastructure Funding Cancer Program 2019$275,294
Funding body: NSW Ministry of Health
Funding body | NSW Ministry of Health |
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Project Team | Conjoint Professor Stephen Ackland, Professor Xu Dong Zhang, Laureate Professor Rodney Scott, Associate Professor Nikki Verrills, Doctor Peter Pockney, Doctor Steve Smith, Doctor Liz Fradgley, Professor Amanda Baker, Doctor Jude Weidenhofer, Conjoint Professor Stephen Ackland |
Scheme | Medical Research Support Program (MRSP) |
Role | Investigator |
Funding Start | 2019 |
Funding Finish | 2019 |
GNo | G1900048 |
Type Of Funding | C2220 - Aust StateTerritoryLocal - Other |
Category | 2220 |
UON | Y |
Testing the impact of an Interactive Health Communication Application on days alive out of hospital and quality of life following surgery for colorectal cancer$132,000
Funding body: Hunter New England Area Health Service
Funding body | Hunter New England Area Health Service |
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Project Team | Doctor Steve Smith, Laureate Professor Robert Sanson-Fisher, Dr Jon Gani, Conjoint Professor Jonathan Gani, Professor Mariko Carey, Doctor Sancha Robinson, Sancha Robinson, Professor Andrew Searles, Conjoint Professor Andrew Searles, Doctor Peter Pockney, Mr Chris Oldmeadow, Doctor Christopher Oldmeadow, Conjoint Associate Professor Ross Kerridge |
Scheme | Partnership Projects Partner Funding |
Role | Lead |
Funding Start | 2019 |
Funding Finish | 2024 |
GNo | G1801077 |
Type Of Funding | C2220 - Aust StateTerritoryLocal - Other |
Category | 2220 |
UON | Y |
A Double-Blind Randomised Placebo-Controlled Trial Assessing the Effect of Peri-Operative Intravenous Lignocaine and Post-Operative Lignocaine Neurovascular Plane Infusion on Natural Killer Ce$60,000
Funding body: Colorectal Surgical Society of Australia and New Zealand Foundation Pty Ltd
Funding body | Colorectal Surgical Society of Australia and New Zealand Foundation Pty Ltd |
---|---|
Project Team | Doctor Steve Smith, Professor Simon Keely, Conjoint Professor Jonathan Gani, Doctor Gang Liu, Doctor Peter Pockney |
Scheme | Research Grant |
Role | Lead |
Funding Start | 2019 |
Funding Finish | 2019 |
GNo | G1901026 |
Type Of Funding | C3112 - Aust Not for profit |
Category | 3112 |
UON | Y |
Randomised clinical trial to assess the feasibility for a larger study comparing the use of three Veno-thrombo-embolic prophylaxis treatments in patients undergoing major abdominal surgery$20,063
Funding body: John Hunter Hospital/ Hunter New England Health
Funding body | John Hunter Hospital/ Hunter New England Health |
---|---|
Project Team | Dr Steve Smith, Natalie Lott, Rosemary Carroll, Dr Nicole Organ, Dr Matthew Sebastian |
Scheme | Research Funding |
Role | Lead |
Funding Start | 2019 |
Funding Finish | 2019 |
GNo | |
Type Of Funding | Internal |
Category | INTE |
UON | N |
FHEAM Equipment Grant to Support Research Activities$14,933
Funding body: Faculty of Health and Medicine, The University of Newcastle
Funding body | Faculty of Health and Medicine, The University of Newcastle |
---|---|
Project Team | Dr Steve Smith, Dr Georgia Carroll |
Scheme | Equipment grant |
Role | Lead |
Funding Start | 2019 |
Funding Finish | 2019 |
GNo | |
Type Of Funding | Internal |
Category | INTE |
UON | N |
The Microbiome of Surgical Site Infections$14,250
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
---|---|
Project Team | Professor Simon Keely, Doctor Steve Smith, Doctor Peter Pockney |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2019 |
Funding Finish | 2019 |
GNo | G1901238 |
Type Of Funding | C3120 - Aust Philanthropy |
Category | 3120 |
UON | Y |
Statistical Analysis Support Grant$6,000
Funding body: Hunter New England Local Health District NSW Health
Funding body | Hunter New England Local Health District NSW Health |
---|---|
Project Team | Dr Steve Smith, Doctor Peter Pockney, Dr Jon Gani, Rosemary Carroll, Natalie Lott |
Scheme | Hunter New England LHD Research and Development Office |
Role | Lead |
Funding Start | 2019 |
Funding Finish | 2019 |
GNo | |
Type Of Funding | Internal |
Category | INTE |
UON | N |
Statistical Support Grant Skin Prep Study Meta-Analysis$5,050
Funding body: Hunter New England Local Health District NSW Health
Funding body | Hunter New England Local Health District NSW Health |
---|---|
Project Team | Dr Steve Smith, Dr Peter Pockney, Conjoint Professor Jon Gani, Dr Jacob Hampton, Dr Sean Park |
Scheme | Hunter New England LHD Research and Development Office |
Role | Lead |
Funding Start | 2019 |
Funding Finish | 2020 |
GNo | |
Type Of Funding | Internal |
Category | INTE |
UON | N |
Statistical Support Grant PIMCO Study$5,050
Funding body: Hunter New England Local Health District
Funding body | Hunter New England Local Health District |
---|---|
Project Team | Dr Steve Smith, Dr Georgia Carroll, Dr Peter Pockney, Associate Professor Simon Keely, Professor Majorie Walker |
Scheme | Research Support and Development Grant |
Role | Lead |
Funding Start | 2019 |
Funding Finish | 2019 |
GNo | |
Type Of Funding | Internal |
Category | INTE |
UON | N |
Ice Machine$4,153
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
---|---|
Project Team | Doctor Steve Smith |
Scheme | Early and Mid-Career Equipment Grant |
Role | Lead |
Funding Start | 2019 |
Funding Finish | 2019 |
GNo | G1900167 |
Type Of Funding | C3120 - Aust Philanthropy |
Category | 3120 |
UON | Y |
20185 grants / $319,268
The role of microbial oxygen sensing in the development of anastomotic leaks$121,525
Funding body: Fisher & Paykel Healthcare Limited
Funding body | Fisher & Paykel Healthcare Limited |
---|---|
Project Team | Professor Simon Keely, Doctor Peter Pockney, Doctor Steve Smith |
Scheme | Research Consultancy |
Role | Investigator |
Funding Start | 2018 |
Funding Finish | 2019 |
GNo | G1701624 |
Type Of Funding | C3211 - International For profit |
Category | 3211 |
UON | Y |
Mary Sawyer Postgraduate Scholarship in Cancer Research$99,750
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
---|---|
Project Team | Dr Georgia Carroll, Professor Simon Keely, Doctor Peter Pockney, Professor Marjorie Walker, Doctor Steve Smith, Doctor Andrea Johns |
Scheme | Postgraduate Research Scholarship |
Role | Investigator |
Funding Start | 2018 |
Funding Finish | 2021 |
GNo | G1800612 |
Type Of Funding | C3120 - Aust Philanthropy |
Category | 3120 |
UON | Y |
Lignocaine Infusion in Colorectal Cancer Patient Immune Cells LICPIC Study$59,993
Funding body: Hunter New England Local Health District
Funding body | Hunter New England Local Health District |
---|---|
Project Team | Doctor Steve Smith, Doctor Peter Pockney |
Scheme | Research Funding |
Role | Lead |
Funding Start | 2018 |
Funding Finish | 2019 |
GNo | G1801298 |
Type Of Funding | C2220 - Aust StateTerritoryLocal - Other |
Category | 2220 |
UON | Y |
Analysis of luminal bacteria at the site of colorectal anastomoses and their association with anastomotic leaks$20,000
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
---|---|
Project Team | Professor Simon Keely, Doctor Peter Pockney, Doctor Steve Smith, Associate Professor Ian Grainge, Doctor Andrea Johns |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2018 |
Funding Finish | 2018 |
GNo | G1701630 |
Type Of Funding | C3120 - Aust Philanthropy |
Category | 3120 |
UON | Y |
Surgicure$18,000
Funding body: Surgicure
Funding body | Surgicure |
---|---|
Project Team | Steve Smith, Stan Chen, Peter Pockney Jon Gani |
Scheme | Donation |
Role | Lead |
Funding Start | 2018 |
Funding Finish | 2019 |
GNo | |
Type Of Funding | Donation - Aust Non Government |
Category | 3AFD |
UON | N |
20175 grants / $414,969
HMRI MRSP Cancer Research Program 2017$358,478
Funding body: NSW Ministry of Health
Funding body | NSW Ministry of Health |
---|---|
Project Team | Conjoint Professor Stephen Ackland, Professor Xu Dong Zhang, Laureate Professor Rodney Scott, Associate Professor Nikki Verrills, Conjoint Professor Jarad Martin, Doctor Steve Smith, Professor Christine Paul, Conjoint Professor Peter Greer, Doctor Anthony Proietto, Doctor Fiona Day, Professor Christopher Scarlett |
Scheme | Medical Research Support Program (MRSP) |
Role | Investigator |
Funding Start | 2017 |
Funding Finish | 2017 |
GNo | G1700603 |
Type Of Funding | C2220 - Aust StateTerritoryLocal - Other |
Category | 2220 |
UON | Y |
CSSANZ Foundation Research Support Grant$27,000
Funding body: Colorectal Surgical Society of Australia and New Zealand Foundation
Funding body | Colorectal Surgical Society of Australia and New Zealand Foundation |
---|---|
Project Team | Dr Steve Smith, Doctor Peter Pockney, Dr Bree Stephensen, Rosemary Carroll |
Scheme | Colorectal Surgical Society of Australia and New Zealand Foundation |
Role | Lead |
Funding Start | 2017 |
Funding Finish | 2018 |
GNo | |
Type Of Funding | External |
Category | EXTE |
UON | N |
John Hunter Hospital Charitable Trust$20,000
Funding body: John Hunter Charitable Trust Grant
Funding body | John Hunter Charitable Trust Grant |
---|---|
Project Team | Dr Steve Smith, Doctor Peter Pockney, Dr Bree Stephensen, Rosemary Carroll |
Scheme | John Hunter Charitable Trust Grant |
Role | Lead |
Funding Start | 2017 |
Funding Finish | 2017 |
GNo | |
Type Of Funding | Internal |
Category | INTE |
UON | N |
Colorectal Surgical Society of Australia and New Zealand Foundation$5,308
Funding body: Colorectal Surgical Society of Australia and New Zealand Foundation
Funding body | Colorectal Surgical Society of Australia and New Zealand Foundation |
---|---|
Project Team | Dr Steve Smith, Doctor Peter Pockney, Dr Bree Stephensen, Rosemary Carroll |
Scheme | Colorectal Surgical Society of Australia and New Zealand Foundation |
Role | Lead |
Funding Start | 2017 |
Funding Finish | 2018 |
GNo | |
Type Of Funding | External |
Category | EXTE |
UON | N |
HMRI MRSP Secial Infrastructure Scheme - Early and Mid-Career Equipment Grant$4,183
Funding body: NSW Ministry of Health
Funding body | NSW Ministry of Health |
---|---|
Project Team | Professor Zsolt Balogh, Doctor Gabrielle Briggs, Doctor Steve Smith |
Scheme | Medical Research Support Program (MRSP) |
Role | Investigator |
Funding Start | 2017 |
Funding Finish | 2017 |
GNo | G1701285 |
Type Of Funding | C2220 - Aust StateTerritoryLocal - Other |
Category | 2220 |
UON | Y |
20161 grants / $150,000
Oesophageal Cancer Research Donation$150,000
Funding body: Private Donation
Funding body | Private Donation |
---|---|
Project Team | Steve Smith, Vanessa Wills |
Scheme | Private Donation |
Role | Investigator |
Funding Start | 2016 |
Funding Finish | 2018 |
GNo | |
Type Of Funding | Donation - Aust Non Government |
Category | 3AFD |
UON | N |
20151 grants / $100,000
Hunter Cancer Research Alliance Staffing Infrastructure Grant$100,000
Funding body: Hunter Cancer Research Alliance (HCRA)
Funding body | Hunter Cancer Research Alliance (HCRA) |
---|---|
Project Team | Dr Steve Smith, Dr James Lynam, Doctor Peter Pockney |
Scheme | Infrastructure Funding |
Role | Investigator |
Funding Start | 2015 |
Funding Finish | 2015 |
GNo | |
Type Of Funding | External |
Category | EXTE |
UON | N |
20141 grants / $8,749,482
Hunter Cancer Research Alliance; HCRA$8,749,482
Funding body: Cancer Institute NSW
Funding body | Cancer Institute NSW |
---|---|
Project Team | Laureate Professor Rodney Scott, Conjoint Professor Stephen Ackland, Conjoint Professor Stephen Ackland, Conjoint Professor Stephen Ackland, Conjoint Professor Stephen Ackland, Doctor Steve Smith, Laureate Professor Robert Sanson-Fisher, Professor Xu Dong Zhang, Doctor Anthony Proietto, Conjoint Professor Peter Greer, Professor Christine Paul, Doctor Stephen Smith, Conjoint Professor Stephen Ackland, Conjoint Professor Stephen Ackland, Conjoint Professor Stephen Ackland, Conjoint Professor Stephen Ackland, Conjoint Professor Stephen Ackland, Conjoint Professor Stephen Ackland |
Scheme | Translational Cancer Research Centre Grants |
Role | Investigator |
Funding Start | 2014 |
Funding Finish | 2021 |
GNo | G1301098 |
Type Of Funding | C2210 - Aust StateTerritoryLocal - Own Purpose |
Category | 2210 |
UON | Y |
20131 grants / $48,656
Providing tailored web-based information to support colorectal cancer patients in their preparation for and recovery from surgery: A feasibility study$48,656
Funding body: Cancer Institute NSW
Funding body | Cancer Institute NSW |
---|---|
Project Team | Laureate Professor Robert Sanson-Fisher, Doctor Steve Smith, Doctor Sancha Robinson, Ms Gill Batt, Conjoint Professor Frans Henskens, Conjoint Associate Professor Ross Kerridge, Doctor Christopher Oldmeadow, Doctor Peter Pockney, Doctor Christopher Hayes |
Scheme | Evidence to Practice Grant |
Role | Investigator |
Funding Start | 2013 |
Funding Finish | 2013 |
GNo | G1300868 |
Type Of Funding | Other Public Sector - State |
Category | 2OPS |
UON | Y |
Dr Steve Smith
Position
Conjoint Associate Professor
School of Medicine and Public Health
College of Health, Medicine and Wellbeing
Contact Details
stephen.smith@newcastle.edu.au |