2024 |
Deeming S, Dolja-Gore X, Gani J, Carroll R, Lott N, Attia J, et al., 'Optimal antiseptic skin preparation agents for minimizing surgical site infection following surgery: cost and cost-effectiveness analysis', BJS Open, 8 (2024)
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2024 |
Lott N, Douglas JL, Magnusson M, Gani J, Reeves P, Connah D, et al., 'Should intermittent pneumatic compression devices be standard therapy for the prevention of venous thromboembolic events in major surgery? Protocol for a randomised clinical trial (IMPOSTERS)', BMJ Open, 14 (2024)
Introduction Venous thromboembolism (VTE) is a recognised postsurgical risk. Current prevention methods involve low molecular weight heparin (LMWH), graduated compression stocking... [more]
Introduction Venous thromboembolism (VTE) is a recognised postsurgical risk. Current prevention methods involve low molecular weight heparin (LMWH), graduated compression stockings (GCS), and intermittent pneumatic compression devices (IPCDs). Australian guidelines, commonly adopted by surgeons, recommend LMWH with GCS and/or IPCDs. IPCDs pose clinical risks, increase care burden, are poorly tolerated, and are costly single-use plastic items. Utilising only LMWH and GCS, without IPCDs, could be more practical, patient-friendly, and cost-effective, with added environmental benefits. Methods This is a multicentre, prospective, two-arm randomised controlled non-inferiority trial at five New South Wales (NSW) hospitals, in Australia. We propose to randomise 4130 participants in a 1:1 ratio between arm A: LMWH+GCS+IPCDs (n=2065) or arm B: LMWH+GCS (n=2065). The primary outcome of interest is symptomatic VTE (deep vein thrombosis/pulmonary embolism) identified at the day 30 phone follow-up (FU), confirmed by ultrasound or imaging. Radiologists interpreting the lower-extremity ultrasonography will be blinded to intervention allocation. Secondary outcomes are quality of life at baseline, days 30 and 90 FU using the 5-level European Quality of Life Score, compliance and adverse events with IPCDs, GCS, and LMWH, as well as healthcare costs (from the perspective of the patient and the hospital), and all-cause mortality. The trial has 90% power to detect a 2% non-inferiority margin to detect a reduction rate of VTE from 4% to 2%. Ethics and dissemination This study has been approved by the Hunter New England Human Research Ethics Committee (2022/ETH02276) protocol V.10, 13 July 2023. Study findings will be presented at local and national conferences and in scientific research journals. Trial registration number ANZCTR12622001527752
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2023 |
Lott N, Smith S, Gani J, Reeves P, 'Intermittent pneumatic compression devices: time to reassess the evidence', ANZ JOURNAL OF SURGERY, 93 812-814 (2023)
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2023 |
Ameh E, Adams C, Alverdy J, An G, Ashley S, Bandy N, et al., 'Acknowledgment of Reviewers 2022', SURGICAL INFECTIONS, 24 97-97 (2023) [C1]
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2023 |
Peters LE, Zhao J, Gelzinnis S, Smith SR, Martin J, Pockney P, 'Use of caller ID and text messaging from cell phones to increase response rates in patient surveys', Research Methods in Medicine & Health Sciences, 4 150-155 (2023) [C1]
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Nova |
2023 |
Lott N, Senanayake T, Carroll R, Gani J, Smith SR, 'Venous thromboembolic prophylaxis: current practice of surgeons in Australia and New Zealand for major abdominal surgery.', BMC Surg, 23 265 (2023) [C1]
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Nova |
2023 |
Smith S, Abuhassanian I, Attia J, Carroll R, Lott N, Hampton J, Gani J, 'Antiseptic Skin Agents to Prevent Surgical Site Infection After Clean Implant Surgery: Subgroup Analysis of the NEWSkin Prep Trial.', Surg Infect (Larchmt), 24 818-822 (2023) [C1]
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Nova |
2023 |
Kwok AMF, Smith SR, Zhao J, Carroll R, Leigh L, Draganic B, 'Topical Lidocaine or Lidocaine/Diltiazem Ointment Following Rubber Band Ligation of Hemorrhoids: A Prospective 3-Armed Randomized Controlled Trial.', Dis Colon Rectum, 66 1110-1117 (2023) [C1]
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2023 |
Vishnoi V, Hoedt EC, Gould T, Carroll G, Carroll R, Lott N, et al., 'A pilot study: intraoperative 16S rRNA sequencing versus culture in predicting colorectal incisional surgical site infection', ANZ Journal of Surgery, 93 2464-2472 (2023) [C1]
Background: Surgical Site Infection (SSI) of the abdominal incision is a dreaded complication following colorectal surgery. Identifying the intraoperative surgical site microbes m... [more]
Background: Surgical Site Infection (SSI) of the abdominal incision is a dreaded complication following colorectal surgery. Identifying the intraoperative surgical site microbes may provide clarity in the pathogenesis of SSIs. Genomic sequencing has revolutionized the ability to identify microbes from clinical samples. Utilization of 16S rRNA amplicon sequencing to characterize the intraoperative surgical site may provide the critical information required to predict and prevent infection in colorectal surgery. Methods: This is a pilot, prospective observational study of 50 patients undergoing elective colorectal resection. At completion of surgery, prior to skin closure, swabs were taken from the subcutaneous tissue of the abdominal incision to investigate the microbial profile. Dual swabs were taken to compare standard culture technique and 16S rRNA sequencing to establish if a microbial profile was associated with postoperative SSI. Results: 8/50 patients developed an SSI, which was more likely in those undergoing open surgery (5/15 33.3% versus 3/35, 8.6%; P = 0.029). 16S rRNA amplicon sequencing was more sensitive in microbial detection compared to traditional culture. Both culture and 16S rRNA demonstrated contamination of the surgical site, predominantly with anaerobes. Culture was not statistically predictive of infection. 16S rRNA amplicon sequencing was not statistically predictive of infection, however, it demonstrated patients with an SSI had an increased biodiversity (not significant) and a greater relative abundance (not significant) of pathogens such as Bacteroidacaea and Enterobacteriaceae within the intraoperative site. Conclusions: 16S rRNA amplicon sequencing has demonstrated a potential difference in the intraoperative microbial profile of those that develop an infection. These findings require validation through powered experiments to determine the overall clinical significance.
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Nova |
2023 |
Gilbert B, Kaiko G, Smith S, Wark P, 'A systematic review of the colorectal microbiome in adult cystic fibrosis patients.', Colorectal Dis, 25 843-852 (2023) [C1]
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Nova |
2023 |
Ajitsaria P, Lott N, Baker A, Lacey J, Magnusson M, Douglas JL, et al., 'Protocol paper for SMART OPS: Shared decision-making Multidisciplinary Approach - a Randomised controlled Trial in the Older adult Population considering Surgery', BMJ OPEN, 13 (2023)
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2023 |
Wyse R, Smith S, Zucca A, Fakes K, Mansfield E, Johnston S-A, et al., 'Effectiveness and cost-effectiveness of a digital health intervention to support patients with colorectal cancer prepare for and recover from surgery: study protocol of the RecoverEsupport randomised controlled trial', BMJ OPEN, 13 (2023)
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2022 |
Reid FS, Stephensen B, Carroll R, Lott N, Attia JR, Smith SR, 'Antiseptic Skin Preparation Agents to Prevent Surgical Site Infection in Colorectal Surgery: A 3-Armed Randomized Controlled Trial.', Dis Colon Rectum, 65 1391-1396 (2022) [C1]
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Nova |
2022 |
Smith SR, Gani J, Carroll R, Lott N, Hampton J, Oldmeadow C, et al., 'Antiseptic Skin Agents to Prevent Surgical Site Infection After Incisional Surgery', Annals of Surgery, 275 842-848 (2022) [C1]
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Nova |
2022 |
Hancock TJ, Hickman P, Kazerooni N, Kennedy M, Kania SA, Dennis M, et al., 'Possible Cross-Reactivity of Feline and White-Tailed Deer Antibodies against the SARS-CoV-2 Receptor Binding Domain', JOURNAL OF VIROLOGY, 96 (2022) [C1]
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2022 |
Zucca A, Mansfield E, Sanson-Fisher R, Wyse R, Johnston S-A, Fakes K, et al., 'Perceived Provision of Perioperative Information and Care by Patients Who Have Undergone Surgery for Colorectal Cancer: A Cross-Sectional Study', INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 19 (2022) [C1]
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Nova |
2022 |
Knight SR, Shaw CA, Pius R, Drake TM, Norman L, Ademuyiwa AO, et al., 'Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study', The Lancet Global Health, 10 e1003-e1011 (2022) [C1]
Background: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility charact... [more]
Background: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study¿a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58¿5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23¿0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research.
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2022 |
Toh JWT, Collins GP, Pathma-Nathan N, El-Khoury T, Engel A, Smith S, et al., 'Attitudes towards Enhanced Recovery after Surgery (ERAS) interventions in colorectal surgery: nationwide survey of Australia and New Zealand colorectal surgeons', Langenbeck's Archives of Surgery, 407 1637-1646 (2022) [C1]
Background: Whilst Enhanced Recovery after Surgery (ERAS) has been widely accepted in the international colorectal surgery community, there remains significant variations in ERAS ... [more]
Background: Whilst Enhanced Recovery after Surgery (ERAS) has been widely accepted in the international colorectal surgery community, there remains significant variations in ERAS programme implementations, compliance rates and best practice recommendations in international guidelines. Methods: A questionnaire was distributed to colorectal surgeons from Australia and New Zealand after ethics approval. It evaluated specialist attitudes towards the effectiveness of specific ERAS interventions in improving short term outcomes after colorectal surgery. The data were analysed using a rating scale and graded response model in item response theory (IRT) on Stata MP, version 15 (StataCorp LP, College Station, TX). Results: Of 300 colorectal surgeons, 95 (31.7%) participated in the survey. Of eighteen ERAS interventions, this study identified eight strategies as most effective in improving ERAS programmes alongside early oral feeding and mobilisation. These included pre-operative iron infusion for anaemic patients (IRT score = 7.82 [95% CI: 6.01¿9.16]), minimally invasive surgery (IRT score = 7.77 [95% CI: 5.96¿9.07]), early in-dwelling catheter removal (IRT score = 7.69 [95% CI: 5.83¿9.01]), pre-operative smoking cessation (IRT score = 7.68 [95% CI: 5.49¿9.18]), pre-operative counselling (IRT score = 7.44 [95% CI: 5.58¿8.88]), avoiding drains in colon surgery (IRT score = 7.37 [95% CI: 5.17¿8.95]), avoiding nasogastric tubes (IRT score = 7.29 [95% CI: 5.32¿8.8]) and early drain removal in rectal surgery (IRT score = 5.64 [95% CI: 3.49¿7.66]). Conclusions: This survey has demonstrated the current attitudes of colorectal surgeons from Australia and New Zealand regarding ERAS interventions. Eight of the interventions assessed in this study including pre-operative iron infusion for anaemic patients, minimally invasive surgery, early in-dwelling catheter removal, pre-operative smoking cessation, pre-operative counselling, avoidance of drains in colon surgery, avoiding nasogastric tubes and early drain removal in rectal surgery should be considered an important part of colorectal ERAS programmes.
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2022 |
Lott N, Robb F, Nolan E, Attia J, Reeves P, Gani J, Smith S, 'Efficacy of intermittent compression devices for thromboembolic prophylaxis in major abdominal surgery: a systematic review and meta-analysis', ANZ JOURNAL OF SURGERY, 92 2926-2934 (2022) [C1]
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Nova |
2022 |
Hampton J, Park SSW, Palazzi K, Oldmeadow C, Carroll R, Attia J, Smith SR, 'The effect of preoperative skin preparation on clinical outcomes with incisional surgery: a network meta-analysis', ANZ JOURNAL OF SURGERY, 92 2859-2867 (2022) [C1]
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Nova |
2022 |
Senanayake T, Loh EJ, Carroll R, Chan V, Smith SR, 'C1q and mobility score in predicting sarcopenia in an Australian cohort of cancer surgery patients', ANZ Journal of Surgery, 92 3204-3208 (2022) [C1]
Background: Sarcopenia has been shown to have significant adverse health outcomes in a range of patient populations. Particularly, sarcopenic patients having cancer surgery are a ... [more]
Background: Sarcopenia has been shown to have significant adverse health outcomes in a range of patient populations. Particularly, sarcopenic patients having cancer surgery are a unique group who demonstrate poorer post-operative outcomes. Currently, the gold standard in diagnosing sarcopenia is through the use of computed tomography. However, the widespread use of imaging to diagnose patients with sarcopenia is neither cost-effective nor practical. Identifying a serum biomarker or a simple mobility scoring system as an alternative diagnostic tool may aid in identifying more patients at risk of sarcopenia. C1q, a novel biomarker, has previously been shown to correlate with sarcopenia. Similarly, we sought to explore whether mobility scores may provide a useful surrogate marker for sarcopenia. Methods: This was a prospective cohort study of patients who presented for colorectal cancer surgery between the dates of 6/10/2016 and 4/10/2017 at John Hunter Hospital. Computed tomography was utilized to calculate the psoas area at the L3 spinal level. Pre-operative blood samples were obtained for C1q analysis and de Morton Mobility Index (DEMMI) was also performed. Results: A total of 51 patients were included in the study. The median age of the patients were 69 years old. We did not demonstrate a correlation between serum C1q and DEMMI scores with psoas area. Conclusion: Our findings suggest that neither C1q nor DEMMI scores are correlated with psoas area in a colorectal cancer population.
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Nova |
2022 |
Bradley C, Hee SW, Andronis L, Persaud K, Hull MA, Todd J, et al., 'REducing Colonoscopies in patients without significant bowEl DiseasE: the RECEDE Study - protocol for a prospective diagnostic accuracy study', BMJ OPEN, 12 (2022)
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2021 |
Knight SR, Shaw CA, Pius R, Drake TM, Norman L, Ademuyiwa AO, et al., 'Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries', LANCET, 397 387-397 (2021) [C1]
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2021 |
Reid FSW, Egoroff N, Pockney PG, Smith SR, 'A systematic scoping review on natural killer cell function in colorectal cancer', Cancer Immunology, Immunotherapy, 70 597-606 (2021) [C1]
Purpose: Natural Killer (NK) cells are a vital part of immune surveillance and have been implicated in colorectal cancer development and prognosis. This systematic review aims to ... [more]
Purpose: Natural Killer (NK) cells are a vital part of immune surveillance and have been implicated in colorectal cancer development and prognosis. This systematic review aims to distil the literature on NK cells as it relates to colorectal cancer. Methods: All published studies over 10¿years relating to NK cells and colorectal cancer were reviewed. All studies publishing in English, searchable via pubmed or through reference review and reporting directly on the nature or function of NK cells in colorectal cancer patients were included. Outcomes were determined as alterations or new information regarding NK cells in colorectal cancer patients. Results: Natural killer cells may be implicated in the development of colorectal cancer and may play a role in prognostication of the disease. NK cells are altered by the treatment (both surgical and medical) of colorectal cancer and it seems likely that they will also be a target for manipulation to improve colorectal cancer survival. Conclusions: NK cell morphology and function are significantly affected by the development of colorectal cancer. Observation of NK cell changes may lead to earlier detection and better prognostication in colorectal cancer. Further study is needed into immunological manipulation of NK cells which may lead to improved colorectal cancer survival.
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Nova |
2021 |
Stephensen BD, Reid F, Shaikh S, Carroll RNR, Smith SR, Pockney P, 'Comment on: C-reactive protein trajectory to predict colorectal anastomotic leak: PREDICT Study by Plate et al.', BRITISH JOURNAL OF SURGERY, 108 E232-E232 (2021)
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2021 |
Toh JWT, Chen G, Yang P, Reza F, Pathmanathan N, El Khoury T, et al., 'Bowel Preparation and Oral Antibiotic Agents for Selective Decontamination in Colorectal Surgery: Current Practice, Perspectives, and Trends in Australia and New Zealand, 2019-2020', SURGICAL INFECTIONS, 22 836-844 (2021) [C1]
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Nova |
2021 |
Storey B, Zhao J, Chern T, Petersson J, Smith S, 'Single-dermatome single-incision laparoscopic right hemicolectomy', ANZ JOURNAL OF SURGERY, 91 192-193 (2021)
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2021 |
Kwok AMF, Thomas NA, Smith SR, 'Sigmoid mesenteric cyst of urogenital origin: A rare cause of bilateral hydroureter', ANZ JOURNAL OF SURGERY, 92 884-886 (2021)
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2021 |
Peters LE, Zhao J, Smith SR, Pockney P, 'Comment on "Opioids After Surgery in the United States Versus the Rest of the World The International Patterns of Opioid Prescribing Multicenter Study''', ANNALS OF SURGERY, 274 E838-E839 (2021)
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2021 |
Wiadji E, Mackenzie L, Reeder P, Gani JS, Carroll R, Smith S, et al., 'Utilization of telehealth by surgeons during the COVID 19 pandemic in Australia: lessons learnt', ANZ JOURNAL OF SURGERY, 91 507-514 (2021) [C1]
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Nova |
2021 |
Wiadji E, Mackenzie L, Reeder P, Gani JS, Ahmadi S, Carroll R, et al., 'Patient perceptions of surgical telehealth consultations during the COVID 19 pandemic in Australia: Lessons for future implementation', ANZ JOURNAL OF SURGERY, 91 1662-1667 (2021) [C1]
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Nova |
2021 |
Chandrapalan S, Hee SW, Widlak MM, Farrugia A, Alam MT, Smith S, Arasaradnam RP, 'Performance of the faecal immunochemical test for the detection of colorectal neoplasms and the role of proton pump inhibitors in their diagnostic accuracy', COLORECTAL DISEASE, 23 1649-1657 (2021) [C1]
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2020 |
Storey B, Smith S, Bateman G, McLeod N, 'Unusual cause for recurrent epididymo-orchitis: fistula from rectal stump to seminal vesicle', ANZ JOURNAL OF SURGERY, 90 164-166 (2020)
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2020 |
Park SSW, Feng D, Smith S, 'A systematic review and meta-analysis comparing intracorporeal anastomosis and extracorporeal anastomosis in minimally invasive colectomies', Mini-invasive Surgery, 2020 (2020) [C1]
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Nova |
2020 |
Daboub JA, Bergemann AD, Smith SR, 'Rethinking an Admissions Program to Align with the Mission of an Innovative Medical School', MEDICAL SCIENCE EDUCATOR, 30 1655-1659 (2020)
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2020 |
Makanyengo SO, Carroll GM, Goggins BJ, Smith SR, Pockney PG, Keely S, 'Systematic Review on the Influence of Tissue Oxygenation on Gut Microbiota and Anastomotic Healing', JOURNAL OF SURGICAL RESEARCH, 249 186-196 (2020) [C1]
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Nova |
2020 |
Carroll GM, Burns GL, Petit JA, Walker MM, Mathe A, Smith SR, et al., 'Does postoperative inflammation or sepsis generate neutrophil extracellular traps that influence colorectal cancer progression? A systematic review', Surgery Open Science, 2 57-69 (2020) [C1]
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Nova |
2020 |
Stephensen BD, Reid F, Shaikh S, Carroll R, Smith SR, Pockney P, 'C-reactive protein trajectory to predict colorectal anastomotic leak: PREDICT Study', British Journal of Surgery, 107 1832-1837 (2020) [C1]
Background: Anastomotic leak is a common complication after colorectal surgery, associated with increased morbidity and mortality, and poorer long-term survival after oncological ... [more]
Background: Anastomotic leak is a common complication after colorectal surgery, associated with increased morbidity and mortality, and poorer long-term survival after oncological resections. Early diagnosis improves short-term outcomes, and may translate into reduced cancer recurrence. Multiple studies have attempted to identify biomarkers to enable earlier diagnosis of anastomotic leak. One study demonstrated that the trajectory of C-reactive protein (CRP) levels was highly predictive of anastomotic leak requiring intervention, with an area under the curve of 0·961. The aim of the present study was to validate this finding externally. Methods: This was a prospective international multicentre observational study of adults undergoing elective colorectal resection with an anastomosis. CRP levels were measured before operation and for 5 days afterwards, or until day of discharge if earlier than this. The primary outcome was anastomotic leak requiring operative or radiological intervention. Results: Between March 2017 and July 2018, 933 patients were recruited from 20 hospitals across Australia, New Zealand, England and Scotland. Some 833 patients had complete CRP data and were included in the primary analysis, of whom 41 (4·9 per cent) developed an anastomotic leak. A change in CRP level exceeding 50 mg/l between any two postoperative days had a sensitivity of 0·85 for detecting a leak, and a high negative predictive value of 0·99 for ruling it out. A change in CRP concentration of more than 50 mg/l between either days 3 and 4 or days 4 and 5 after surgery had a high specificity of 0·96¿0·97, with positive likelihood ratios of 4·99¿6·44 for a leak requiring intervention. Conclusion: This study confirmed the value of CRP trajectory in accurately ruling out an anastomotic leak after colorectal resection.
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Nova |
2020 |
Zhao J, Peters L, Gelzinnis S, Carroll R, Nolan J, Di Sano S, et al., 'Post-discharge opioid prescribing after laparoscopic appendicectomy and cholecystectomy', ANZ JOURNAL OF SURGERY, 90 1014-1018 (2020) [C1]
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Nova |
2019 |
Carroll GM, Burns GL, Petit JA, Walker MM, Mathe A, Smith SR, et al., 'Does Surgery Generate Neutrophil Extracellular Traps that Influence Colorectal Cancer Progression? A Systematic Review', SSRN Electronic Journal,
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2019 |
Tepper J, Corelli K, Navathe R, Smith S, Baxter JK, 'A retrospective cohort study of fetal assessment following preterm premature rupture of membranes', INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 145 83-90 (2019)
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2019 |
Stevenson ARL, Solomon MJ, Brown CSB, Lumley JW, Hewett P, Clouston AD, et al., 'Disease-free Survival and Local Recurrence After Laparoscopic-assisted Resection or Open Resection for Rectal Cancer The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial', ANNALS OF SURGERY, 269 596-602 (2019)
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2019 |
Weiner DE, Park M, Tighiouart H, Joseph AA, Carpenter MA, Goyal N, et al., 'Albuminuria and Allograft Failure, Cardiovascular Disease Events, and All-Cause Death in Stable Kidney Transplant Recipients: A Cohort Analysis of the FAVORIT Trial', AMERICAN JOURNAL OF KIDNEY DISEASES, 73 51-61 (2019)
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2019 |
Fildes J, Smith S, Neumayer L, Madura J, Fry D, Talamonti M, 'Persistently Elevated Glucagon-Like Peptide-1 Levels among Critically Ill Surgical Patients after Sepsis and Development of Chronic Critical Illness and Dismal Long-Term Outcomes Discussion', JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 229 67-68 (2019) |
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2019 |
Ade P, Aguirre J, Ahmed Z, Aiola S, Ali A, Alonso D, et al., 'The Simons Observatory: science goals and forecasts', JOURNAL OF COSMOLOGY AND ASTROPARTICLE PHYSICS, (2019)
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2019 |
Stephensen BD, Clarke L, McManus B, Clark S, Carroll R, Holz P, Smith SR, 'The LAPLAP study: a randomized placebo-controlled clinical trial assessing postoperative functional recovery using intraperitoneal local anaesthetic in laparoscopic colorectal surgery', Colorectal Disease, 21 1183-1191 (2019) [C1]
Aim: Postoperative pain remains a major factor in recovery from colorectal resection. There is increasing interest in opioid-sparing analgesia, and intraperitoneal local anaesthet... [more]
Aim: Postoperative pain remains a major factor in recovery from colorectal resection. There is increasing interest in opioid-sparing analgesia, and intraperitoneal local anaesthetic (IPLA) has recently been shown to be useful in minor laparoscopic and open colorectal procedures. The aim of this study was to evaluate the impact of IPLA on functional recovery following major laparoscopic surgery. In this controlled trial, mobility, as measured by the De Morton Mobility Index (DEMMI), was used as a surrogate for postoperative functional recovery. Method: Patients undergoing laparoscopic colorectal resection were randomized either to continuous ropivacaine (0.2% at 4¿6¿ml/h) or to saline (0.9%) which were administered via intraperitoneal catheter for 3¿days postoperatively. Results were analysed in a double-blind manner. DEMMIs were assessed on postoperative days 1, 2, 3, 7 and 30, and data on pain, opioid consumption, gut and respiratory function, length of stay (LOS) and complications were recorded. Results: Ninety-six patients were recruited. There was no difference in primary outcome (i.e., functional recovery) between IPLA and placebo groups. Opioid consumption and LOS were similar between groups, and no differences were found for any secondary outcome measure. There were no adverse events related to ropivacaine. Conclusion: Infusional intraperitoneal local anaesthetic appears to be safe but does not improve functional recovery or analgesic consumption following elective laparoscopic colorectal surgery, in the setting of an established enhanced recovery programme.
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Nova |
2018 |
Smith SR, Murray D, Pockney PG, Bendinelli C, Draganic BD, Carroll R, 'Tranexamic Acid for Lower GI Hemorrhage: A Randomized Placebo-Controlled Clinical Trial', Diseases of the Colon and Rectum, 61 99-106 (2018) [C1]
BACKGROUND: Lower GI hemorrhage is a common source of morbidity and mortality. Tranexamic acid is an antifibrinolytic that has been shown to reduce blood loss in a variety of clin... [more]
BACKGROUND: Lower GI hemorrhage is a common source of morbidity and mortality. Tranexamic acid is an antifibrinolytic that has been shown to reduce blood loss in a variety of clinical conditions. Information regarding the use of tranexamic acid in treating lower GI hemorrhage is lacking. OBJECTIVE: The aim of this trial was to determine the clinical efficacy of tranexamic acid when used for lower GI hemorrhage. DESIGN: This was a prospective, double-blind, placebo-controlled, randomized clinical trial. SETTINGS: The study was conducted at a tertiary referral university hospital in Australia. PATIENTS: Consecutive patients aged >18 years with lower GI hemorrhage requiring hospital admission from November 2011 to January 2014 were screened for trial eligibility (N = 265). INTERVENTIONS: A total of 100 patients were recruited after exclusions and were randomly assigned 1:1 to either tranexamic acid or placebo. MAIN OUTCOME MEASURES: The primary outcome was blood loss as determined by reduction in hemoglobin levels. The secondary outcomes were transfusion rates, transfusion volume, intervention rates for bleeding, length of hospital stay, readmission, and complication rates. RESULTS: There was no difference between groups with respect to hemoglobin drop (11 g/L of tranexamic acid vs 13 g/L of placebo; p = 0.9445). There was no difference with respect to transfusion rates (14/49 tranexamic acid vs 16/47 placebo; p = 0.661), mean transfusion volume (1.27 vs 1.93 units; p = 0.355), intervention rates (7/49 vs 13/47; p = 0.134), length of hospital stay (4.67 vs 4.74 d; p = 0.934), readmission, or complication rates. No complications occurred as a direct result of tranexamic acid use. LIMITATIONS: A larger multicenter trial may be required to determine whether there are more subtle advantages with tranexamic acid use in some of the secondary outcomes. CONCLUSIONS: Tranexamic acid does not appear to decrease blood loss or improve clinical outcomes in patients presenting with lower GI hemorrhage in the context of this trial. see Video Abstract at http://links.lww.com/DCR/A453.
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Nova |
2018 |
Rutledge A, Carroll G, Smith S, Gani J, 'Response to Re: How to do it: use of the Alexis wound protector as a laparostomy device', ANZ JOURNAL OF SURGERY, 88 117-118 (2018)
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2018 |
Carroll GM, Hampton J, Carroll R, Smith SR, 'Mobility scores as a predictor of length of stay in general surgery: a prospective cohort study', ANZ Journal of Surgery, 88 860-864 (2018) [C1]
Background: Post-operative length of stay (LOS) is an increasingly important clinical indicator in general surgery. Despite this, no tool has been validated to predict LOS or read... [more]
Background: Post-operative length of stay (LOS) is an increasingly important clinical indicator in general surgery. Despite this, no tool has been validated to predict LOS or readiness for discharge in general surgical patients. The de Morton Mobility Index (DEMMI) is a functional mobility assessment tool that has been validated in rehabilitation patient populations. In this prospective cohort study, we aimed to identify if trends in DEMMI scores were associated with discharge within 1 week and overall LOS in general surgical patients. Methods: A total of 161 patients who underwent elective gastrointestinal resections were included. DEMMI scores were performed preoperatively, on days 1, 2, 3 and 30 post-operative. Statistical analysis was performed to identify any association between DEMMI scores and discharge within 1 week and LOS. Results: Functional recovery (measured by achieving 80% of baseline DEMMI score by post-operative day 1) was significantly associated with discharge within 1 week. Presence of a stoma was associated with longer LOS. The area under the receiver operating characteristic curve using functional recovery on post-operative day 1 as a predictor of discharge within 1 week is 0.772. Conclusion: The DEMMI score is a fast, easy and useful tool to, on post-operative day 1, predict discharge within 1 week. The utility of this is to act as an anticipatory trigger for more proactive and efficient discharge planning in the early post-operative period, and there is potential to use the DEMMI as a comparator in clinical trials to assess functional recovery.
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Nova |
2018 |
Fry W, Smith S, Schuerer D, Chapman W, 'Resuscitative Endovascular Balloon Occlusion of the Aorta: Implementation and Preliminary Results at an Academic Level I Trauma Center Discussion', JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 227 133-134 (2018) |
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2018 |
Roberts ST, Patel K, Smith SR, 'Impact of avoiding post-operative urinary catheters on outcomes following colorectal resection in an ERAS programme: No IDUC and ERAS programmes', ANZ Journal of Surgery, 88 E390-E394 (2018) [C1]
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Nova |
2018 |
Burnett D, Smith SR, Young CJ, 'The Surgical Management of Pilonidal Disease is Uncertain Because of High Recurrence Rates', CUREUS JOURNAL OF MEDICAL SCIENCE, 10 (2018)
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2018 |
Smith SR, Pockney P, Holmes R, Doig F, Attia J, Holliday E, et al., 'Biomarkers and anastomotic leakage in colorectal surgery: C-reactive protein trajectory is the gold standard.', ANZ journal of surgery, 88 440-444 (2018) [C1]
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Nova |
2018 |
Holmes R, Smith SR, Carroll R, Holz P, Mehrotra R, Pockney P, 'Randomized clinical trial to assess the ideal mode of delivery for local anaesthetic abdominal wall blocks.', ANZ journal of surgery, 88 786-791 (2018) [C1]
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Nova |
2018 |
Smith SR, Holmes R, Pockney P, Holz P, Carroll R, Mehrotra R, 'Response to Re: Randomized clinical trial to assess the ideal mode of delivery for local anaesthetic abdominal wall blocks', ANZ JOURNAL OF SURGERY, 88 805-806 (2018)
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2018 |
Cooper JA, Parsons N, Stinton C, Mathews C, Smith S, Halloran SP, et al., 'Risk-adjusted colorectal cancer screening using the FIT and routine screening data: development of a risk prediction model', BRITISH JOURNAL OF CANCER, 118 285-293 (2018)
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2018 |
Cavers D, Calanzani N, Orbell S, Vojt G, Steele RJC, Brownlee L, et al., 'Development of an evidence-based brief 'talking' intervention for non-responders to bowel screening for use in primary care: stakeholder interviews', BMC FAMILY PRACTICE, 19 (2018)
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2017 |
Penna M, Hompes R, Arnold S, Wynn G, Austin R, Warusavitarne J, et al., 'Transanal Total Mesorectal Excision: International Registry Results of the First 720 Cases', Annals of Surgery, 266 111-117 (2017) [C1]
Objective: This study aims to report short-term clinical and oncological outcomes from the international transanal Total Mesorectal Excision (taTME) registry for benign and malign... [more]
Objective: This study aims to report short-term clinical and oncological outcomes from the international transanal Total Mesorectal Excision (taTME) registry for benign and malignant rectal pathology. Background: TaTME is the latest minimally invasive transanal technique pioneered to facilitate difficult pelvic dissections. Outcomes have been published from small cohorts, but larger series can further assess the safety and efficacy of taTME in the wider surgical population. Methods: Data were analyzed from 66 registered units in 23 countries. The primary endpoint was "good-quality TME surgery." Secondary endpoints were short-term adverse events. Univariate and multivariate regression analyses were used to identify independent predictors of poor specimen outcome. Results: A total of 720 consecutively registered cases were analyzed comprising 634 patients with rectal cancer and 86 with benign pathology. Approximately, 67% were males with mean BMI 26.5 kg/m 2. Abdominal or perineal conversion was 6.3% and 2.8%, respectively. Intact TME specimens were achieved in 85%, with minor defects in 11% and major defects in 4%. R1 resection rate was 2.7%. Postoperative mortality and morbidity were 0.5% and 32.6% respectively. Risk factors for poor specimen outcome (suboptimal TME specimen, perforation, and/or R1 resection) on multivariate analysis were positive CRM on staging MRI, low rectal tumor <2 cm from anorectal junction, and laparoscopic transabdominal posterior dissection to <4 cm from anal verge. Conclusions: TaTME appears to be an oncologically safe and effective technique for distal mesorectal dissection with acceptable short-term patient outcomes and good specimen quality. Ongoing structured training and the upcoming randomized controlled trials are needed to assess the technique further.
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Nova |
2017 |
Lunyera J, Smith SR, 'Heavy metal nephropathy: considerations for exposure analysis', KIDNEY INTERNATIONAL, 92 548-550 (2017)
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2017 |
Merhi B, Shireman T, Carpenter MA, Kusek JW, Jacques P, Pfeffer M, et al., 'Serum Phosphorus and Risk of Cardiovascular Disease, All-Cause Mortality, or Graft Failure in Kidney Transplant Recipients: An Ancillary Study of the FAVORIT Trial Cohort', AMERICAN JOURNAL OF KIDNEY DISEASES, 70 377-385 (2017)
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2017 |
Gani JS, 'How to do it: Use of the Alexis wound protector as a laparostomy device', ANZJSurg, (2017)
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2017 |
Schmiegel W, Scott RJ, Dooley S, Lewis W, Meldrum CJ, Pockney P, et al., 'Blood-based detection of
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Nova |
2017 |
Moss S, Mathews C, Day J, Smith S, Seaman HE, Snowball J, Halloran SP, 'Increased uptake and improved outcomes of bowel cancer screening with a faecal immunochemical test: results from a pilot study within the national screening programme in England', GUT, 66 1631-1644 (2017)
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2017 |
Smith SG, Wardle J, Atkin W, Raine R, McGregor LM, Vart G, et al., 'Reducing the socioeconomic gradient in uptake of the NHS bowel cancer screening Programme using a simplified supplementary information leaflet: a cluster-randomised trial', BMC CANCER, 17 (2017)
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2017 |
Calanzani N, Cavers D, Vojt G, Orbell S, Steele RJC, Brownlee L, et al., 'Is an opportunistic primary care-based intervention for non-responders to bowel screening feasible and acceptable? A mixed-methods feasibility study in Scotland', BMJ OPEN, 7 (2017)
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2017 |
Lecky DM, Nakiboneka-Ssenabulya D, Nichols T, Hawkey P, Turner K, Chung K-T, et al., 'Informing future research for carriage of multiresistant Gram-negative bacteria: problems with recruiting to an English stool sample community prevalence study', BMJ OPEN, 7 (2017)
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2016 |
Oladeji LO, Raley JA, Smith S, Perez JL, Mcgwin G, Ponce BA, 'Behind the Match Process: Is There Any Financial Difference Lurking Below the Specialty of Choice?', AMERICAN SURGEON, 82 1163-1168 (2016)
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2016 |
Smith J, Moore EE, Smith S, Tyburski J, Rhee P, 'Establishing Benchmarks for Resuscitation of Traumatic Circulatory Arrest: Success-to-Rescue and Survival among 1,708 Patients Discussion', JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 223 50-51 (2016) |
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2016 |
Kost A, Genao I, Lee JW, Smith SR, 'Response: Re: Clinical Decisions Made in Primary Care Clinics Before and After Choosing Wisely (TM)', JOURNAL OF THE AMERICAN BOARD OF FAMILY MEDICINE, 29 167-168
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2016 |
Raine R, Duffy SW, Wardle J, Solmi F, Morris S, Howe R, et al., 'Impact of general practice endorsement on the social gradient in uptake in bowel cancer screening', BRITISH JOURNAL OF CANCER, 114 321-326 (2016)
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2016 |
Raine R, Moss SM, von Wagner C, Atkin W, Hans IK, Howe R, et al., 'A national cluster-randomised controlled trial to examine the effect of enhanced reminders on the socioeconomic gradient in uptake in bowel cancer screening', BRITISH JOURNAL OF CANCER, 115 1479-1486 (2016)
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2016 |
Wardle J, von Wagner C, Kralj-Hans I, Halloran SP, Smith SG, McGregor LM, et al., 'Effects of evidence-based strategies to reduce the socioeconomic gradient of uptake in the English NHS Bowel Cancer Screening Programme (ASCEND): four cluster-randomised controlled trials', LANCET, 387 751-759 (2016)
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2016 |
McGregor LM, von Wagner C, Atkin W, Kralj-Hans I, Halloran SP, Handley G, et al., 'Reducing the Social Gradient in Uptake of the NHS Colorectal Cancer Screening Programme Using a Narrative-Based Information Leaflet: A Cluster-Randomised Trial', GASTROENTEROLOGY RESEARCH AND PRACTICE, 2016 (2016)
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2015 |
Kost A, Genao I, Lee JW, Smith SR, 'Clinical Decisions Made in Primary Care Clinics Before and After Choosing Wisely (TM)', JOURNAL OF THE AMERICAN BOARD OF FAMILY MEDICINE, 28 471-474
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2015 |
Smith S, Pockney P, Attia J, 'Corrigendum: A Meta-analysis on the Effect of Sham Feeding Following Colectomy: Should Gum Chewing Be Included in Enhanced Recovery After Surgery Protocols?', Diseases of the colon and rectum, 58 e416 (2015) [O1]
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2015 |
Smith SR, Draganic B, Pockney P, Holz P, Holmes R, Mcmanus B, Carroll R, 'Transversus abdominis plane blockade in laparoscopic colorectal surgery: a double-blind randomized clinical trial', INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 30 1237-1245 (2015) [C1]
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Nova |
2014 |
Malone AF, Phelan PJ, Hall G, Cetincelik U, Homstad A, Alonso AS, et al., 'Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis', KIDNEY INTERNATIONAL, 86 1253-1259 (2014)
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2014 |
Carpenter MA, John A, Weir MR, Smith SR, Hunsicker L, Kasiske BL, et al., 'BP, Cardiovascular Disease, and Death in the Folic Acid for Vascular Outcome Reduction in Transplantation Trial', JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 25 1554-1562 (2014)
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2014 |
Swensen SJ, Duncan JR, Gibson R, Muething SE, LeBuhn R, Rexford J, et al., 'An Appeal for Safe and Appropriate Imaging of Children', JOURNAL OF PATIENT SAFETY, 10 121-124 (2014)
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2014 |
Ho YM, Smith SR, Pockney P, Lim P, Attia J, 'A Meta-analysis on the Effect of Sham Feeding Following Colectomy: Should Gum Chewing Be Included in Enhanced Recovery After Surgery Protocols?', DISEASES OF THE COLON & RECTUM, 57 115-126 (2014) [C1]
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Nova |
2014 |
Smith SR, 'The author replies', Diseases of the Colon and Rectum, 57 (2014)
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2014 |
Ho YM, Gani J, Draganic BD, Smith SR, 'Bladeless stoma creation using muscle separation technology: a novel technique', TECHNIQUES IN COLOPROCTOLOGY, 18 299-300 (2014) [C3]
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Nova |
2013 |
Wilhelm S, O'Connell K, Berber E, McHenry CR, Smith SR, Prinz RA, Snyder S, 'The utility of routine preoperative cervical ultrasonography in patients undergoing thyroidectomy for differentiated thyroid cancer DISCUSSION', SURGERY, 154 701-703 (2013)
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2013 |
Claridge J, Dwyer C, Smith SR, Marshall SJ, Smith J, 'Radiographic assessment of ground-level falls in elderly patients: Is the "PAN-SCAN" overdoing it? DISCUSSION', SURGERY, 154 820-822 (2013)
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2013 |
Westervelt JD, Alexander BD, Costa SF, Miller SE, Howell DN, Smith SR, 'Detection of BK polyomavirus after kidney transplantation: a comparison of urine electron microscopy with plasma polymerase chain reaction', CLINICAL TRANSPLANTATION, 27 E42-E48
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2013 |
Malone AF, Sparks MA, Howell DN, Middleton JP, Smith SR, Lehrich RW, 'IgG(4)-related tubulointerstitial nephritis associated with chronic lymphocytic leukemia', JOURNAL OF NEPHROLOGY, 26 1195-1198
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2013 |
Lim P, Morris OJ, Nolan G, Moore S, Draganic B, Smith SR, 'Sham Feeding With Chewing Gum After Elective Colorectal Resectional Surgery A Randomized Clinical Trial', ANNALS OF SURGERY, 257 1016-1024 (2013) [C1]
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Nova |
2013 |
Young JM, Butow PN, Walsh J, Durcinoska I, Dobbins TA, Rodwell L, et al., 'Multicenter Randomized Trial of Centralized Nurse-Led Telephone-Based Care Coordination to Improve Outcomes After Surgical Resection for Colorectal Cancer: The CONNECT Intervention', JOURNAL OF CLINICAL ONCOLOGY, 31 3585-+ (2013)
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2013 |
Morris OJ, Smith S, Draganic B, 'Comparison of bulking agents in the treatment of fecal incontinence: A prospective randomized clinical trial', Techniques in Coloproctology, 17 517-523 (2013) [C1]
Background: We sought to compare two synthetic injectable bulking agents, with known efficacy (PTQ¿: a silicone biomaterial and Durasphere ®: pyrolytic carbon-coated beads), in th... [more]
Background: We sought to compare two synthetic injectable bulking agents, with known efficacy (PTQ¿: a silicone biomaterial and Durasphere ®: pyrolytic carbon-coated beads), in the form of a randomised clinical trial. Methods: Circumferential injection of either agent was performed under local anesthesia and sedation as a day-case procedure. The primary outcome measure was the Wexner incontinence scale. Secondary measures were the short-form 36 (SF-36) quality of life assessment and manometry (maximum resting and squeeze pressures). Follow-up was at 6 weeks, 6 and 12 months. Results: Thirty-five patients were randomised, 17 to PTQ® and 18 to Durasphere®. Early closure of the trial occurred, due to the removal of the agent PTQ®, from the Australian Pharmaceutical Benefits scheme. Wexner incontinence scores were significantly better than baseline, in both groups, at 6 weeks and 6 months (P < 0.05), although the improvements were not significant at 12 months. There was no significant improvement for either agent, from baseline, in mean SF-36 scores at any follow-up sessions. There was no significant difference between the two bulking agents, with regard to both Wexner and SF-36 scores, at any of the follow-up sessions. Complications occurred in one patient in the PTQ group (perianal abscess) and did not occur in any of the patients in the Durasphere group. Conclusions: This trial appears to show that both synthetic agents PTQ ® and Durasphere® are effective and safe, although long-term improvement is limited. In this trial, there appears to be no difference in efficacy between the two agents, over a 12-month follow-up period. © 2013 Springer-Verlag Italia.
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Nova |
2012 |
Smith SR, 'What Is Professionalism? reply', ARCHIVES OF INTERNAL MEDICINE, 172 197-197 (2012)
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2012 |
Smith SR, Montgomery LG, Williams JW, 'Treatment of Mild to Moderate Sinusitis', ARCHIVES OF INTERNAL MEDICINE, 172 510-513 (2012)
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2012 |
Smith SR, '"So That's Why They Didn't Get Better!"', ARCHIVES OF INTERNAL MEDICINE, 172 514-515 (2012)
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2012 |
Leung LB, Busch AM, Nottage SL, Arellano N, Glieberman E, Busch NJ, Smith SR, 'Approach to Antihypertensive Adherence: A Feasibility Study on the Use of Student Health Coaches for Uninsured Hypertensive Adults', BEHAVIORAL MEDICINE, 38 19-27 (2012)
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2012 |
Goetzinger AM, Blumenthal JA, O'Hayer CV, Babyak MA, Hoffman BM, Ong L, et al., 'Stress and coping in caregivers of patients awaiting solid organ transplantation', CLINICAL TRANSPLANTATION, 26 97-104
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2012 |
Moore SE, Reid KC, Draganic B, Smith S, 'Randomized clinical trial of ropivacaine wound infusion following laparoscopic colorectal surgery', Techniques in Coloproctology, 16 431-436 (2012) [C1]
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Nova |
2012 |
Mihalik JE, Smith S, Toevs CC, Putnam AT, Foster JE, 'The use of contrast-enhanced ultrasound for the evaluation of solid abdominal organ injury in patients with blunt abdominal trauma', JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 73 1100-1105 (2012)
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2011 |
Aguilar I, Berger ZD, Casher D, Choi RY, Green JB, Harding EG, et al., 'The "Top 5" Lists in Primary Care Meeting the Responsibility of Professionalism', ARCHIVES OF INTERNAL MEDICINE, 171 1385-1390 (2011)
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2011 |
Bostom AG, Carpenter MA, Kusek JW, Levey AS, Hunsicker L, Pfeffer MA, et al., 'Homocysteine-Lowering and Cardiovascular Disease Outcomes in Kidney Transplant Recipients Primary Results From the Folic Acid for Vascular Outcome Reduction in Transplantation Trial', CIRCULATION, 123 1763-1770 (2011)
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2011 |
Smith SR, 'A Recipe for Medical Schools to Produce Primary Care Physicians.', NEW ENGLAND JOURNAL OF MEDICINE, 364 496-497 (2011)
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2011 |
Westervelt JD, Smith SR, 'Can an arteriovenous dialysis access be salvaged when a clinically significant steal develops?', SEMINARS IN DIALYSIS, 24 392-393
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2011 |
Smith S, 'Author's reply: Randomized clinical trial of short-term outcomes following purse-string versus conventional closure of ileostomy wounds (Br J Surg 2010; 97: 1511-1517)', British Journal of Surgery, 98 458 (2011) [C3]
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2011 |
Morris OJ, Draganic B, Smith S, 'Does a learning curve exist in endorectal two-dimensional ultrasound accuracy?', Techniques in Coloproctology, 15 301-311 (2011) [C1]
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Nova |
2010 |
Reid K, Pockney PG, Pollitt T, Draganic B, Smith SR, 'Randomized clinical trial of short-term outcomes following purse-string versus conventional closure of ileostomy wounds', British Journal of Surgery, 97 1511-1517 (2010) [C1]
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2010 |
Reid K, Pockney P, Draganic B, Smith S, 'Barrier wound protection decreases surgical site infection in open elective colorectal surgery: A randomized clinical trial', Diseases of the Colon & Rectum, 53 1374-1380 (2010) [C1]
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Nova |
2010 |
Smith S, Solomon M, 'Functional comparisons between open and laparoscopic rectopexy', Gastroenterologie Clinique Et Biologique, 34 505-507 (2010) [C3]
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2010 |
Smith S, 'Will a market deliver quality and efficiency in health care better than central planning ever could? Yes', BRITISH MEDICAL JOURNAL, 340 (2010)
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2009 |
Harvey I, Smith S, Patterson I, 'The use of quilted full thickness skin grafts in the lower limb - reliable results with early mobilization', JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, 62 969-972 (2009)
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2008 |
Gopalratnam PC, Smith SR, 'Process Safety Progress: Continuity and Transition', PROCESS SAFETY PROGRESS, 27 265-265 (2008)
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2008 |
Smith SR, 'What Does a Clinical Competency Curriculum Look Like?', JOURNAL OF VETERINARY MEDICAL EDUCATION, 35 354-358
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2008 |
Byrne CM, Smith SR, Solomon MJ, Young JM, Eyers AA, Young CJ, 'Long-Term Functional Outcomes After Laparoscopic and Open Rectopexy for the Treatment of Rectal Prolapse', DISEASES OF THE COLON & RECTUM, 51 1597-1604 (2008)
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2008 |
Wilkes A, Wills V, Smith S, 'PATIENT KNOWLEDGE OF THE RISKS OF POST-SPLENECTOMY SEPSIS', ANZ JOURNAL OF SURGERY, 78 867-870 (2008)
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2007 |
Scherzinger M, Smith S, 'From blatant to latent protest (and back again): on the politics of theatrical spectacle in Madonna's 'American Life'', POPULAR MUSIC, 26 211-229 (2007)
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2007 |
Smith S, Brasel KJ, Hoyt DB, Petersen SR, Talamonti M, Jurkovich GJ, Low DE, 'Length of stay - An appropriate quality measure? Discussion', ARCHIVES OF SURGERY, 142 465-466 (2007)
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2007 |
Smith SR, Cookson J, Mckendree J, Harden RM, 'Patient-centred learning - back to the future', MEDICAL TEACHER, 29 33-37 (2007)
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2007 |
Lehrich RW, Pun PH, Tanenbaum ND, Smith SR, Middleton JP, 'Automated external defibrillators and survival from cardiac arrest in the outpatient hemodialysis clinic', JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 18 312-320 (2007)
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2007 |
Smith SR, 'Online availability of PSP articles', PROCESS SAFETY PROGRESS, 26 262-262 (2007)
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2007 |
Dineen S, Smith S, Arko FR, 'Successful percutaneous angioplasty and stenting of the radial artery in a patient with chronic upper extremity ischemia and digital gangrene', JOURNAL OF ENDOVASCULAR THERAPY, 14 426-428 (2007)
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2006 |
Plumb TJ, Greenberg A, Smith SR, Butterly DW, Pham TTN, Fields TA, Howell DN, 'Postinfectious glomerulonephritis in renal allograft recipients', TRANSPLANTATION, 82 1224-1228 (2006)
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2006 |
Palmer SM, Burch LH, Mir S, Smith SR, Kuo PC, Herczyk WF, et al., 'Donor polymorphisms in Toll-like receptor-4 influence the development of rejection after renal transplantation', CLINICAL TRANSPLANTATION, 20 30-36
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2005 |
Lehrich RW, Rocha PN, Reinsmoen N, Greenberg A, Butterly DW, Howell DN, Smith SR, 'Intravenous immunoglobulin and plasmapheresis in acute humoral rejection: Experience in renal allograft transplantation', HUMAN IMMUNOLOGY, 66 350-358 (2005)
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2004 |
Nelson R, Solomon M, Smith S, 'Review: Medical therapies are less effective than surgery for anal fissure', Evidence-Based Medicine, 9 112 (2004)
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2003 |
Rocha PN, Butterly DW, Greenberg A, Reddan DN, Tuttle-Newhall J, Collins BH, et al., 'Beneficial effect of plasmapheresis and intravenous immunoglobulin on renal allograft survival of patients with acute humoral rejection', TRANSPLANTATION, 75 1490-1495 (2003)
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2003 |
Smith SR, Dollase RH, Boss JA, 'Assessing students' performances in a competency-based curriculum', ACADEMIC MEDICINE, 78 97-107 (2003)
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2002 |
Smith SR, Butterly DW, 'Declining influence of race on the outcome of living-donor renal transplantation', AMERICAN JOURNAL OF TRANSPLANTATION, 2 282-286 (2002)
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2001 |
Smith SR, Butterly DW, Alexander BD, Greenberg A, 'Viral infections after renal transplantation', AMERICAN JOURNAL OF KIDNEY DISEASES, 37 659-676 (2001)
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1999 |
Howell DN, Smith SR, Butterly DW, Klassen PS, Krigman HR, Burchette JL, Miller SE, 'Diagnosis and management of BK polyomavirus interstitial nephritis in renal transplant recipients', TRANSPLANTATION, 68 1279-1288 (1999)
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1999 |
Smith SR, Dollase R, 'AMEE guide No. 14: Outcome-based education: Part 2 - Planning, implementing and evaluating a competency-based curriculum', MEDICAL TEACHER, 21 15-22 (1999)
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1997 |
vanderPoll T, Jansen PM, Montegut WJ, Braxton CC, Calvano SE, Stackpole SA, et al., 'Effects of IL-10 on systemic inflammatory responses during sublethal primate endotoxemia', JOURNAL OF IMMUNOLOGY, 158 1971-1975 (1997)
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1995 |
SMITH SR, MINDA SA, SAMSA GP, HARRELL FE, GUNNELLS JC, COFFMAN TM, BUTTERLY DW, 'LATE WITHDRAWAL OF CYCLOSPORINE IN STABLE RENAL-TRANSPLANT RECIPIENTS', AMERICAN JOURNAL OF KIDNEY DISEASES, 26 487-494 (1995)
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1995 |
CONLON PJ, HOWELL DN, MACIK G, KOVALIK EC, SMITH SR, 'THE RENAL MANIFESTATIONS AND OUTCOME OF THROMBOTIC THROMBOCYTOPENIC PURPURA HEMOLYTIC-UREMIC SYNDROME IN ADULTS', NEPHROLOGY DIALYSIS TRANSPLANTATION, 10 1189-1193 (1995)
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1995 |
CONLON PJ, SMITH SR, 'TRANSMISSION OF CANCER WITH CADAVERIC DONOR ORGANS', JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 6 54-60 (1995)
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1994 |
SMITH SR, UTTERBACK CM, PARR DD, 'ALABAMA SOCIETY HELPS MEMBERS DOCUMENT PHARMACEUTICAL CARE (APRIL 1, 1994, ASHP AFFILIATES) (VOL 13, PG 1, 1993)', AMERICAN JOURNAL OF HOSPITAL PHARMACY, 51 1474-1474 (1994) |
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1992 |
TILTON RG, BAIER LD, HARLOW JE, SMITH SR, OSTROW E, WILLIAMSON JR, 'DIABETES-INDUCED GLOMERULAR DYSFUNCTION - LINKS TO A MORE REDUCED CYTOSOLIC RATIO OF NADH/NAD+', KIDNEY INTERNATIONAL, 41 778-788 (1992)
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1991 |
SMITH SR, SVETKEY LP, DENNIS VW, 'RACIAL-DIFFERENCES IN THE INCIDENCE AND PROGRESSION OF RENAL DISEASES', KIDNEY INTERNATIONAL, 40 815-822 (1991)
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1990 |
PENNLINE KJ, PELLERITO F, DAFONSECA M, MONAHAN P, SIEGEL MI, SMITH SR, 'FLOW CYTOMETRIC ANALYSIS OF RECOMBINANT MURINE GM-CSF (RMUGM-CSF) INDUCED CHANGES IN THE DISTRIBUTION OF SPECIFIC CELL-POPULATIONS INVIVO', CYTOMETRY, 11 283-291 (1990)
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1989 |
WALLER DJ, SMITH SR, WARNOCK JT, 'SITUATIONAL THEORY OF LEADERSHIP', AMERICAN JOURNAL OF HOSPITAL PHARMACY, 46 2336-2341 (1989)
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1989 |
SMITH SR, HAFFNER CA, KENDALL MJ, 'THE INFLUENCE OF NIFEDIPINE AND DILTIAZEM ON SERUM THEOPHYLLINE CONCENTRATION-TIME PROFILES', JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 14 403-408 (1989)
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1989 |
LEWIS HM, KENDALL MJ, SMITH SR, BRATTY JR, 'A COMPARISON OF THE EFFECTS OF FLOSEQUINAN, A NEW VASODILATOR, AND PROPRANOLOL ON SUB-MAXIMAL EXERCISE IN HEALTHY-VOLUNTEERS', BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 27 547-552 (1989)
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1988 |
WALLER DJ, SMITH SR, 'MEDICATION HISTORIES SHOULD NOT BE INCLUDED IN MEASURES OF COMPREHENSIVE CLINICAL SERVICES', AMERICAN JOURNAL OF HOSPITAL PHARMACY, 45 1668-1668 (1988)
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1988 |
SMITH SR, KENDALL MJ, 'RANITIDINE VERSUS CIMETIDINE - A COMPARISON OF THEIR POTENTIAL TO CAUSE CLINICALLY IMPORTANT DRUG-INTERACTIONS', CLINICAL PHARMACOKINETICS, 15 44-56 (1988)
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1987 |
WALLER DJ, SMITH SR, 'USE OF INFUSION DEVICES WITH TOTAL NUTRIENT ADMIXTURES', AMERICAN JOURNAL OF HOSPITAL PHARMACY, 44 1570-& (1987)
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1987 |
UMLAND SP, SMITH SR, STRAUSSER HR, 'PRODUCTION OF AND RESPONSIVENESS TO INTERLEUKIN-2 IN AUTOIMMUNE BXSB MICE', CELLULAR IMMUNOLOGY, 107 158-171 (1987)
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1987 |
SMITH SR, WILKINS MR, JACK DB, KENDALL MJ, LAUGHER S, 'PHARMACOKINETIC INTERACTIONS BETWEEN FELODIPINE AND METOPROLOL', EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 31 575-578 (1987)
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1987 |
HALL PE, SMITH SR, KENDALL MJ, 'THE EFFECT OF PROPRANOLOL ON THE RISE IN PLASMA AMMONIA DURING MODEST EXERCISE', EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 32 149-151 (1987)
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1987 |
GREGG MR, JACK DB, SMITH SR, KENDALL MJ, 'THE PHARMACOKINETICS OF OXPRENOLOL FOLLOWING ORAL AND RECTAL DOSING - A COMPARISON OF DELIVERY SYSTEMS AND ROUTES OF ADMINISTRATION', JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 12 91-99 (1987)
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1987 |
HALL PE, SMITH SR, JACK DB, KENDALL MJ, 'THE INFLUENCE OF BETA-ADRENOCEPTOR BLOCKADE ON THE LIPOLYTIC RESPONSE TO EXERCISE', JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 12 101-106 (1987)
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1987 |
SMITH SR, 'TOLERANCE - A RESPONSE TO LONG-TERM TREATMENT WITH BETA-2-RECEPTOR STIMULANTS', JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 12 137-139 (1987)
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1987 |
SMITH SR, KENDALL MJ, LOBO J, BEERAHEE A, JACK DB, WILKINS MR, 'RANITIDINE AND CIMETIDINE - DRUG-INTERACTIONS WITH SINGLE DOSE AND STEADY-STATE NIFEDIPINE ADMINISTRATION', BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 23 311-315 (1987)
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1986 |
WALLER DJ, SMITH SR, 'ASSURING THE QUALITY OF A CLINICAL PHARMACOKINETICS SERVICE', AMERICAN JOURNAL OF HOSPITAL PHARMACY, 43 2184-2188 (1986)
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1986 |
SMITH SR, KENDALL MJ, 'POTENTIATION OF THE ADVERSE-EFFECTS OF INTRAVENOUS TERBUTALINE BY ORAL THEOPHYLLINE', BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 21 451-453 (1986)
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1986 |
SMITH SR, KENDALL MJ, 'DOWNGRADING OF BIOCHEMICAL AND CARDIOVASCULAR-RESPONSES TO AN INTRAVENOUS-INFUSION OF TERBUTALINE FOLLOWING CHRONIC TREATMENT WITH ORAL TERBUTALINE', INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 24 1-3 (1986)
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1985 |
SMITH SR, GOVE I, KENDALL MJ, 'BETA-AGONISTS AND POTASSIUM', LANCET, 1 1394-1394 (1985)
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1985 |
SMITH SR, GOVE RI, STOCKLEY RA, 'CHEST INFECTIONS - ARE WE MAKING PROGRESS', JOURNAL OF CLINICAL AND HOSPITAL PHARMACY, 10 243-255 (1985)
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1985 |
BOBER LA, TIVEY LC, DAFONSECA M, SMITH SR, WATNICK AS, 'INHIBITION OF COLLAGEN-II ARTHRITIS BY SIMULTANEOUS ADMINISTRATION OF CONCANAVALIN-A AND OTHER SUBSTANCES WITH ANTIGEN EMULSION', IMMUNOPHARMACOLOGY, 9 97-107 (1985)
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1985 |
JACK DB, KENDALL MJ, LAUGHER SJ, SMITH SR, 'REPRODUCIBILITY OF OXPRENOLOL PLASMA-CONCENTRATIONS IN YOUNG FEMALE VOLUNTEERS FOLLOWING ORAL-ADMINISTRATION OF AN OXPRENOLOL OROS DOSAGE FORM', BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 19 S185-S190 (1985)
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1984 |
SMITH SR, UMLAND S, TERMINELLI C, WATNICK AS, 'A STUDY OF THE MECHANISM OF CON A-INDUCED IMMUNOSUPPRESSION INVIVO', CELLULAR IMMUNOLOGY, 87 147-158 (1984)
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1984 |
SMITH SR, KENDALL MJ, RYDER C, LAUGHER S, 'LACK OF INFLUENCE OF BETA-ADRENERGIC-BLOCKADE ON SERUM POTASSIUM DURING AN INFUSION OF POTASSIUM', EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 26 425-427 (1984)
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1984 |
HALL PE, KENDALL MJ, SMITH SR, 'BETA-BLOCKERS AND FATIGUE', JOURNAL OF CLINICAL AND HOSPITAL PHARMACY, 9 283-291 (1984)
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1984 |
KENDALL MJ, JACK DB, QUARTERMAN CP, SMITH SR, ZAMAN R, 'BETA-ADRENOCEPTOR BLOCKER PHARMACOKINETICS AND THE ORAL-CONTRACEPTIVE PILL', BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 17 S87-S89 (1984)
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1984 |
KENDALL MJ, JACK DB, LAUGHER SJ, LOBO J, SMITH SR, 'LACK OF A PHARMACOKINETIC INTERACTION BETWEEN NIFEDIPINE AND THE BETA-ADRENOCEPTOR BLOCKERS METOPROLOL AND ATENOLOL', BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 18 331-335 (1984)
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1984 |
SMITH SR, RYDER C, KENDALL MJ, HOLDER R, 'CARDIOVASCULAR AND BIOCHEMICAL RESPONSES TO NEBULIZED SALBUTAMOL IN NORMAL SUBJECTS', BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 18 641-644 (1984)
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1983 |
SMITH SR, BLACKLEDGE G, 'THERAPEUTIC PROGRESS .8. DO THE NEWER CYTO-TOXIC DRUGS REPRESENT A SIGNIFICANT ADVANCE IN THE TREATMENT OF CANCER', JOURNAL OF CLINICAL AND HOSPITAL PHARMACY, 8 103-113 (1983)
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1983 |
KENDALL MJ, SMITH SR, 'ADRENERGIC BLOCKING-AGENTS', JOURNAL OF CLINICAL AND HOSPITAL PHARMACY, 8 155-173 (1983)
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1983 |
SMITH SR, 'ALPHA-ADRENERGIC BLOCKING-AGENTS IN THE TREATMENT OF ASTHMA', JOURNAL OF CLINICAL AND HOSPITAL PHARMACY, 8 201-208 (1983)
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1983 |
SMITH SR, GIBSON R, BRADLEY D, KENDALL MJ, 'FAILURE OF INDOMETHACIN TO MODIFY BETA-ADRENOCEPTOR BLOCKADE', BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 15 267-268 (1983)
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1983 |
SMITH SR, KENDALL MJ, WORTHINGTON DJ, HOLDER R, 'CAN THE BIOCHEMICAL RESPONSES TO A BETA-2-ADRENOCEPTOR STIMULANT BE USED TO ASSESS THE SELECTIVITY OF BETA-ADRENOCEPTOR BLOCKERS', BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 16 557-560 (1983)
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1982 |
KENDALL MJ, SMITH SR, THOMSON MH, 'CAPTOPRIL - A NEW TREATMENT FOR SEVERE CONGESTIVE HEART-FAILURE', JOURNAL OF CLINICAL AND HOSPITAL PHARMACY, 7 231-244 (1982)
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1982 |
SMITH SR, 'COMPETITION, PROFIT, AND THE HMO', NEW ENGLAND JOURNAL OF MEDICINE, 307 503-504 (1982)
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1981 |
SMITH SR, TERMINELLI C, KIPILMAN CT, SMITH Y, 'COMPARATIVE EFFECTS OF AZATHIOPRINE, CYCLOPHOSPHAMIDE AND FRENTIZOLE ON CELLULAR-IMMUNITY IN MICE', JOURNAL OF IMMUNOPHARMACOLOGY, 3 133-170 (1981)
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1976 |
SMITH SR, PETILLO J, 'IGE PRODUCTION IN 5 INBRED RAT STRAINS FOLLOWING IMMUNIZATION WITH ALUM-PRECIPITATED EGG-ALBUMIN', INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY, 52 21-31 (1976)
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1976 |
SMITH SR, 'POLITICAL TORTURE AND PHYSICIANS', NEW ENGLAND JOURNAL OF MEDICINE, 295 1019-1019 (1976)
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1975 |
SMITH SR, LAMM ME, POWERS ML, 'SPLEEN-CELLS OF PHENOTYPICALLY TL+ MICE DO NOT CONTAIN INTRACELLULAR TL ANTIGENS', IMMUNOGENETICS, 1 591-594 (1975)
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1974 |
SMITH SR, LAMM ME, POWERS ML, BOYSE EA, 'SUBCELLULAR REPRESENTATION OF MURINE THYMUS LEUKEMIA (TL) ANTIGENS IN PHENOTYPICALLY TL+ AND TL- CELLS', JOURNAL OF IMMUNOLOGY, 113 1098-1106 (1974)
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1973 |
PETILLO J, SMITH SR, 'REAGINIC RESPONSE IN RATS TO ALUM PRECIPITATED ANTIGENS .1. TIME COURSE OF APPEARANCE OF ANTI-EGG ALBUMIN REAGINS AND POTENTIATION OF RESPONSE WITH NIPPOSTRONGYLUS-BRASILIENSIS', INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY, 44 309-320 (1973)
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1973 |
SMITH SR, HWANG A, EICHELBERGER J, RANDELL P, 'REAGINIC RESPONSE IN RATS TO ALUM PRECIPITATED ANTIGENS .2. POTENTIATION OF IGGA AND IGE RESPONSES TO DINITROPHENYLATED BOVINE GAMMA-GLOBULIN WITH NIPPOSTRONGYLUS-BRASILIENSIS', INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY, 44 382-395 (1973)
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1972 |
SMITH SR, LOWRANCE JL, 'SINGLE PHOTOELECTRON EXCITATION OF PHOSPHORS', PUBLICATIONS OF THE ASTRONOMICAL SOCIETY OF THE PACIFIC, 84 154-+ (1972)
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1972 |
SMITH SR, HWANG A, PETILLO J, 'FURTHER STUDIES WITH POTENTIATED REAGIN RESPONSE TO EGG ALBUMIN', INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY, 43 145-& (1972)
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CLARKE AF, JACK DB, KENDALL MJ, SMITH SR, 'THE PHARMACOKINETICS OF ORAL AND INTRAVENOUS PRENALTEROL IN YOUNG, HEALTHY-VOLUNTEERS', BIOPHARMACEUTICS & DRUG DISPOSITION, 7 47-52
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