Dr Cino Bendinelli

Dr Cino Bendinelli

Conjoint Professor

School of Medicine and Public Health

Career Summary

Biography

I am a double-certified General Surgeon specialising in trauma and endocrine surgery at John Hunter Hospital and a Conjoint Associate Professor at the University of Newcastle. I obtained my Medical Degree with honours from the University of Pisa, Italy, and am a Fellow of the Royal Australasian College of Surgeons. I have a strong interest in trauma and surgery education and am coordinator and lecturer of the Torso Trauma module in the Master of Traumatology program, at the University of Newcastle.

Current research projects focus on surgical outcomes, trauma management and thyroid cancer surgery, parathyroid disease:
1. Multicentre international randomised controlled trial: Closed Or Open after Laparotomy for source control laparotomy in severe complicated intra-abdominal sepsis (COOL). National Lead Investigator.
2. Multicentre randomised controlled trial: Operative fixation of displaced, painful rib fractures – outcomes & quality of life.
3. Randomised controlled trial: Scalpel vs electrocautery skin incisions in thyroid surgery to compare cosmesis and wound healing. Principal Investigator.
4. Blood brain barrier permeability disturbance after traumatic brain injury.
5. Randomised controlled trial: High-dose preoperative cholecalciferol to prevent long term post-thyroidectomy hypoparathyroidism. Principal Investigator.
6. Quality of life after thyroid surgery for benign and malignant disease
7. Mitocondria activity in parathyroid disease.

I have also published in areas including the role of prehospital intubation and advanced brain imaging in severe traumatic brain injury (PhD); post-operative outcomes in patients undergoing parathyroid surgery, minimally-invasive video-assisted thyroid and parathyroid surgery; traditional versus laparoscopic approaches to adrenal surgery; minimally-invasive parathyroidectomy in pregnancy; and acute management of retrosternal goitre.


Qualifications

  • Post Graduate Diploma in General Surgery, University of Pisa - Italy
  • Bachelor of Medicine, University of Pisa - Italy

Keywords

  • Parathyroid
  • Thyroid cancer
  • Trauma

Languages

  • Italian (Mother)

Fields of Research

Code Description Percentage
110323 Surgery 50
110399 Clinical Sciences not elsewhere classified 50
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (3 outputs)

Year Citation Altmetrics Link
2017 Weber DG, Bendinelli C, 'Damage control surgery for emergency general surgery', Acute Care Surgery Handbook 387-401 (2017)
DOI 10.1007/978-3-319-15341-4_22
2014 Bendinelli C, Yoshino O, 'Surgical treatment of duodenal trauma', Trauma Surgery: Volume 2: Thoracic and Abdominal Trauma 135-149 (2014)

© Springer-Verlag Italia 2014. Duodenal injury remains to be a lethal injury. The high mortality and complication rates are due to difficulties in diagnosis resulting in delayed r... [more]

© Springer-Verlag Italia 2014. Duodenal injury remains to be a lethal injury. The high mortality and complication rates are due to difficulties in diagnosis resulting in delayed recognition and associated injuries such as pancreatic injury and retroperitoneal vascular injuries. Diagnosis can be done perioperatively or intraoperatively. Importantly, clinical judgments have to be based on the combination of mechanisms, clinical signs, and radiological evaluations if possible. In the operation, the strategy is usually simple including primary repair and omentum patch. Nevertheless, if more complicated procedures are required, the principles of damage control surgery need to be followed since definitive repair can be performed later. Although conservative treatment is possible, surgeons need to be aware of alternative options available.

DOI 10.1007/978-88-470-5459-2_10
2012 Bendinelli C, Balogh ZJ, 'Laparoscopy in trauma patients', Advances in Laparoscopic Surgery, InTech, Rijeka, Croatia 43-52 (2012) [B2]
Co-authors Zsolt Balogh

Journal article (75 outputs)

Year Citation Altmetrics Link
2020 Amico F, Anning R, Bendinelli C, Balogh ZJ, Participants of the 2019 World Society of Emergency Surgery (WSES) Nijmegen splenic injury collaboration group, 'Grade III blunt splenic injury without contrast extravasation - World Society of Emergency Surgery Nijmegen consensus practice.', World J Emerg Surg, 15 46 (2020)
DOI 10.1186/s13017-020-00319-y
Co-authors Zsolt Balogh
2020 Bendinelli C, 'Gunshot wounds to the colon', ANZ JOURNAL OF SURGERY, 90 408-409 (2020)
DOI 10.1111/ans.15749
2020 Bendinelli C, Ku D, King KL, Nebauer S, Balogh ZJ, 'Trauma patients with prehospital Glasgow Coma Scale less than nine: not a homogenous group', European Journal of Trauma and Emergency Surgery, 46 873-878 (2020) [C1]

© 2019, Springer-Verlag GmbH Germany, part of Springer Nature. Purpose: Prehospital guidelines stratify and manage patients with Glasgow Coma Scale (GCS) less than nine and any si... [more]

© 2019, Springer-Verlag GmbH Germany, part of Springer Nature. Purpose: Prehospital guidelines stratify and manage patients with Glasgow Coma Scale (GCS) less than nine and any sign of head injury as affected by severe traumatic brain injury (STBI). We hypothesized that this group of patients is so inhomogeneous that uniform treatment guidelines cannot be advocated. Methods: Patients (2005¿2012) with prehospital GCS below nine and abbreviated injury scale head and neck above two were identified from trauma registry. Patients with acute lethal injuries, isolated neck injuries, extubated within 24¿h or transferred interhospitally were excluded. Patients were dichotomized based on the worst prehospital GCS (recorded before sedatives) into two groups: GCS 3¿5 and GCS 6¿8. These were statistically compared using univariate analysis. Results: The GCS 3¿5 group (99 patients) when compared with the GCS 6¿8 group (49 patients) had shorter prehospital times (63 vs. 79¿min; p < 0.05), more frequent episodes of both hypoxia (30.3% vs. 7.7%; p < 0.05) and hypotension (26.7% vs. 6.4%; p < 0.05), more often required craniectomy (15.1% vs. 4.0%; p = 0.05) and higher mortality (33.3% vs. 2%; p < 0.05). In the GCS 3¿5 group, prehospital endotracheal intubation was attempted more often (57.5% vs. 28.6%, p < 0.05) and was more often successful (39.3% vs. 10.2%; p = 0.05). Length of stay in ICU did not differ. Conclusions: STBI patients are fundamentally different based on whether their initial GCS falls into 3¿5 or 6¿8 category. Recommendations from trials investigating trauma patients with GCS less than nine as one group should be translated with caution to clinical practice.

DOI 10.1007/s00068-019-01139-9
Citations Scopus - 2Web of Science - 2
Co-authors Zsolt Balogh
2020 Di Saverio S, Podda M, De Simone B, Ceresoli M, Augustin G, Gori A, et al., 'Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines', WORLD JOURNAL OF EMERGENCY SURGERY, 15 (2020) [C1]
DOI 10.1186/s13017-020-00306-3
Citations Scopus - 13Web of Science - 8
Co-authors Zsolt Balogh
2020 Balogh ZJ, Way TL, Bendinelli C, Warren K-RJ, 'Current concepts on haemorrhage control in severe trauma', ANZ JOURNAL OF SURGERY, 90 406-408 (2020)
DOI 10.1111/ans.15873
Co-authors Zsolt Balogh
2019 Rowe CW, Arthurs S, O Neill CJ, Hawthorne J, Carroll R, Wynne K, Bendinelli C, 'High-dose preoperative cholecalciferol to prevent post-thyroidectomy hypocalcaemia: A randomized, double-blinded placebo-controlled trial', Clinical Endocrinology, 90 343-350 (2019) [C1]

© 2018 John Wiley &amp; Sons Ltd. Objective: Post-thyroidectomy hypocalcaemia is a significant cause of morbidity and prolonged hospitalization, usually due to transient parathy... [more]

© 2018 John Wiley & Sons Ltd. Objective: Post-thyroidectomy hypocalcaemia is a significant cause of morbidity and prolonged hospitalization, usually due to transient parathyroid gland damage, treated with calcium and vitamin D supplementation. We present a randomized, double-blinded placebo-controlled trial of preoperative loading with high-dose cholecalciferol (300¿000 IU) to reduce post-thyroidectomy hypocalcaemia. Patients and Measurements: Patients (n¿=¿160) presenting for thyroidectomy at tertiary hospitals were randomized 1:1 to cholecalciferol (300¿000¿IU) or placebo 7¿days prior to thyroidectomy. Ten patients withdrew prior to surgery. The primary outcome was post-operative hypocalcaemia (corrected calcium <2.1¿mmol/L in first 180¿days). Results: The study included 150 patients undergoing thyroidectomy for Graves¿ disease (31%), malignancy (20%) and goitre (49%). Mean pre-enrolment vitamin D was 72¿±¿26¿nmol/L. Postoperative hypocalcaemia occurred in 21/72 (29%) assigned to cholecalciferol and 30/78 (38%) participants assigned to placebo (P¿=¿0.23). There were no differences in secondary end-points between groups. In pre-specified stratification, baseline vitamin D status did not predict hypocalcaemia, although most individuals were vitamin D replete at baseline. Post-hoc stratification by day 1 parathyroid hormone (PTH) (<10¿pg/mL, low vs =10¿pg/mL, normal) was explored due to highly divergent rates of hypocalcaemia in these groups. Using a Cox regression model, the hazard ratio for hypocalcaemia in the cholecalciferol group was 0.56 (95%CI 0.32-0.98, P¿=¿0.04) after stratification for Day 1 PTH. Further clinical benefits were observed in these subgroups. Conclusions: Pre-thyroidectomy treatment with high-dose cholecalciferol did not reduce the overall rate of hypocalcaemia following thyroidectomy. In subgroups stratified by day 1 PTH status, improved clinical outcomes were noted.

DOI 10.1111/cen.13897
Citations Web of Science - 1
Co-authors Katie-Jane Wynne, Christopher W Rowe
2019 Cooper S, Bendinelli C, Bivard A, Parsons M, Balogh ZJ, 'When a Slice Is Not Enough! Comparison of Whole-Brain versus Standard Limited-Slice Perfusion Computed Tomography in Patients with Severe Traumatic Brain Injury', JOURNAL OF CLINICAL MEDICINE, 8 (2019) [C1]
DOI 10.3390/jcm8050701
Co-authors Mark Parsons, Zsolt Balogh, Andrew Bivard
2019 Ferreira D, Vilayur E, Gao M, Sankoorikal C, Bendinelli C, 'Calcitriol loading before total parathyroidectomy with autotransplant in patients with end-stage kidney disease: does it prevent postoperative hypocalcaemia?', INTERNAL MEDICINE JOURNAL, 49 886-893 (2019)
DOI 10.1111/imj.14209
2019 Rowe CW, Faulkner S, Paul JW, Tolosa JM, Gedye C, Bendinelli C, et al., 'The precursor for nerve growth factor (proNGF) is not a serum or biopsy-rinse biomarker for thyroid cancer diagnosis.', BMC endocrine disorders, 19 128 (2019) [C1]
DOI 10.1186/s12902-019-0457-1
Co-authors John Attia, Jonathan Paul, Craig Gedye, Sam Faulkner, Hubert Hondermarck, Christopher W Rowe, Katie-Jane Wynne, Roger Smith
2019 Henegan J, McGrath S, Shah K, Bendinelli C, 'On the use of autofluorescence for detection of intrathyroidal parathyroid adenoma', ANZ JOURNAL OF SURGERY, 90 916-917 (2019)
DOI 10.1111/ans.15425
Citations Scopus - 1Web of Science - 1
2019 Doig CJ, Page SA, McKee JL, Moore EE, Abu-Zidan FM, Carroll R, et al., 'Ethical considerations in conducting surgical research in severe complicated intra-abdominal sepsis', World Journal of Emergency Surgery, 14 (2019)

© 2019 The Author(s). Background: Severe complicated intra-abdominal sepsis (SCIAS) has high mortality, thought due in part to progressive bio-mediator generation, systemic inflam... [more]

© 2019 The Author(s). Background: Severe complicated intra-abdominal sepsis (SCIAS) has high mortality, thought due in part to progressive bio-mediator generation, systemic inflammation, and multiple organ failure. Treatment includes early antibiotics and operative source control. At surgery, open abdomen management with negative-peritoneal-pressure therapy (NPPT) has been hypothesized to mitigate MOF and death, although clinical equipoise for this operative approach exists. The Closed or Open after Laparotomy (COOL) study (https://clinicaltrials.gov/ct2/show/NCT03163095) will prospectively randomize eligible patients intra-operatively to formal abdominal closure or OA with NPTT. We review the ethical basis for conducting research in SCIAS. Main body: Research in critically ill incapacitated patients is important to advance care. Conducting research among SCIAS is complicated due to the severity of illness including delirium, need for emergent interventions, diagnostic criteria confirmed only at laparotomy, and obtundation from anaesthesia. In other circumstances involving critically ill patients, clinical experts have worked closely with ethicists to apply principles that balance the rights of patients whilst simultaneously permitting inclusion in research. In Canada, the Tri-Council Policy Statement-2 (TCPS-2) describes six criteria that permit study enrollment and randomization in such situations: (a) serious threat to the prospective participant requires immediate intervention; (b) either no standard efficacious care exists or the research offers realistic possibility of direct benefit; (c) risks are not greater than that involved in standard care or are clearly justified by prospect for direct benefits; (d) prospective participant is unconscious or lacks capacity to understand the complexities of the research; (e) third-party authorization cannot be secured in sufficient time; and (f) no relevant prior directives are known to exist that preclude participation. TCPS-2 criteria are in principle not dissimilar to other (inter)national criteria. The COOL study will use waiver of consent to initiate enrollment and randomization, followed by surrogate or proxy consent, and finally delayed informed consent in subjects that survive and regain capacity. Conclusions: A delayed consent mechanism is a practical and ethical solution to challenges in research in SCIAS. The ultimate goal of consent is to balance respect for patient participants and to permit participation in new trials with a reasonable opportunity for improved outcome and minimal risk of harm.

DOI 10.1186/s13017-019-0259-9
Citations Scopus - 3
Co-authors Zsolt Balogh
2019 Ioannou LJ, Serpell J, Dean J, Bendinelli C, Gough J, Lisewski D, et al., 'Development of a binational thyroid cancer clinical quality registry: A protocol paper', BMJ Open, 9 (2019)

© 2019 Author(s) (or their employer(s)). Introduction The occurrence of thyroid cancer is increasing throughout the developed world and since the 1990s has become the fastest incr... [more]

© 2019 Author(s) (or their employer(s)). Introduction The occurrence of thyroid cancer is increasing throughout the developed world and since the 1990s has become the fastest increasing malignancy. In 2014, a total of 2693 Australians and 302 New Zealanders were diagnosed with thyroid cancer, with this number projected to rise to 3650 in 2018. The purpose of this protocol is to establish a binational population-based clinical quality registry with the aim of monitoring and improving the quality of care provided to patients diagnosed with thyroid cancer in Australia and New Zealand. Methods and analysis The Australian and New Zealand Thyroid Cancer Registry (ANZTCR) aims to capture clinical data for all patients over the age of 16 years with thyroid cancer, confirmed by histopathology report, who have been diagnosed, assessed or treated at a contributing hospital. A multidisciplinary steering committee was formed which, with operational support from Monash University, established the ANZTCR in early 2017. The pilot phase of the registry is currently operating in Victoria, New South Wales, Queensland, Western Australia and South Australia, with over 20 sites expected to come on board across Australia in 2018. A modified Delphi process was undertaken to determine the clinical quality indicators to be reported by the registry, and a minimum data set was developed comprising information regarding thyroid cancer diagnosis, pathology, surgery and 90-day follow-up. Future plans The establishment of the ANZTCR provides the opportunity for Australia and New Zealand to further understand current practice in the treatment of thyroid cancer and identify variation in outcomes. The engagement of endocrine surgeons in supporting this initiative is crucial. While the pilot registry has a focus on early clinical outcomes, it is anticipated that future collection of longer term outcome data particularly for patients with poor prognostic disease will add significant further value to the registry.

DOI 10.1136/bmjopen-2018-023723
2018 Smith SR, Murray D, Pockney PG, Bendinelli C, Draganic BD, Carroll R, 'Tranexamic Acid for Lower GI Hemorrhage: A Randomized Placebo-Controlled Clinical Trial', Diseases of the Colon and Rectum, 61 99-106 (2018) [C1]

© 2017 The American Society of Colon and Rectal Surgeons, Inc. BACKGROUND: Lower GI hemorrhage is a common source of morbidity and mortality. Tranexamic acid is an antifibrinolyti... [more]

© 2017 The American Society of Colon and Rectal Surgeons, Inc. BACKGROUND: Lower GI hemorrhage is a common source of morbidity and mortality. Tranexamic acid is an antifibrinolytic that has been shown to reduce blood loss in a variety of clinical conditions. Information regarding the use of tranexamic acid in treating lower GI hemorrhage is lacking. OBJECTIVE: The aim of this trial was to determine the clinical efficacy of tranexamic acid when used for lower GI hemorrhage. DESIGN: This was a prospective, double-blind, placebo-controlled, randomized clinical trial. SETTINGS: The study was conducted at a tertiary referral university hospital in Australia. PATIENTS: Consecutive patients aged >18 years with lower GI hemorrhage requiring hospital admission from November 2011 to January 2014 were screened for trial eligibility (N = 265). INTERVENTIONS: A total of 100 patients were recruited after exclusions and were randomly assigned 1:1 to either tranexamic acid or placebo. MAIN OUTCOME MEASURES: The primary outcome was blood loss as determined by reduction in hemoglobin levels. The secondary outcomes were transfusion rates, transfusion volume, intervention rates for bleeding, length of hospital stay, readmission, and complication rates. RESULTS: There was no difference between groups with respect to hemoglobin drop (11 g/L of tranexamic acid vs 13 g/L of placebo; p = 0.9445). There was no difference with respect to transfusion rates (14/49 tranexamic acid vs 16/47 placebo; p = 0.661), mean transfusion volume (1.27 vs 1.93 units; p = 0.355), intervention rates (7/49 vs 13/47; p = 0.134), length of hospital stay (4.67 vs 4.74 d; p = 0.934), readmission, or complication rates. No complications occurred as a direct result of tranexamic acid use. LIMITATIONS: A larger multicenter trial may be required to determine whether there are more subtle advantages with tranexamic acid use in some of the secondary outcomes. CONCLUSIONS: Tranexamic acid does not appear to decrease blood loss or improve clinical outcomes in patients presenting with lower GI hemorrhage in the context of this trial. see Video Abstract at http://links.lww.com/DCR/A453.

DOI 10.1097/DCR.0000000000000943
Citations Scopus - 6Web of Science - 7
Co-authors Peter Pockney, Stephen Smith
2018 Bendinelli C, Ku D, Nebauer S, King KL, Howard T, Gruen R, et al., 'A tale of two cities: prehospital intubation with or without paralysing agents for traumatic brain injury.', ANZ journal of surgery, 88 455-459 (2018) [C1]
DOI 10.1111/ans.14479
Citations Scopus - 2Web of Science - 1
Co-authors Zsolt Balogh
2018 Ten Broek RPG, Krielen P, Di Saverio S, Coccolini F, Biffl WL, Ansaloni L, et al., 'Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2017 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group', WORLD JOURNAL OF EMERGENCY SURGERY, 13 (2018) [C1]
DOI 10.1186/s13017-018-0185-2
Citations Scopus - 37Web of Science - 40
Co-authors Zsolt Balogh
2018 Bendinelli C, Gray A, Suradi H, Weber DG, Acharya S, Price A, Mcgrath S, 'Pursuing the second ipsilateral gland during minimally invasive video-assisted parathyroidectomy', ANZ Journal of Surgery, 88 E308-E312 (2018) [C1]
DOI 10.1111/ans.13956
2017 De Simone B, Del Rio P, Catena F, Fallani G, Bendinelli C, Napoli JA, et al., 'Preoperative localization of parathyroid adenoma in video-assisted era: is cervical ultrasound or Tc-99m Sesta MIBI scintigraphy better?', MINERVA CHIRURGICA, 72 375-382 (2017)
DOI 10.23736/S0026-4733.17.07359-X
2017 Rowe CW, Paul JW, Gedye C, Tolosa JM, Bendinelli C, McGrath S, Smith R, 'Targeting the TSH receptor in thyroid cancer', Endocrine-Related Cancer, 24 R191-R202 (2017) [C1]

© 2017 Society for Endocrinology Printed in Great Britain. Recent advances in the arena of theranostics have necessitated a re-examining of previously established fields. The exis... [more]

© 2017 Society for Endocrinology Printed in Great Britain. Recent advances in the arena of theranostics have necessitated a re-examining of previously established fields. The existing paradigm of therapeutic thyroid-stimulating hormone receptor (TSHR) targeting in the post-surgical management of differentiated thyroid cancer using levothyroxine and recombinant human thyroid-stimulating hormone (TSH) is well understood. However, in an era of personalized medicine, and with an increasing awareness of the risk profile of longstanding pharmacological hyperthyroidism, it is imperative clinicians understand the molecular basis and magnitude of benefit for individual patients. Furthermore, TSHR has been recently re-conceived as a selective target for residual metastatic thyroid cancer, with pilot data demonstrating effective targeting of nanoparticles to thyroid cancers using this receptor as a target. This review examines the evidence for TSHR signaling as an oncogenic pathway and assesses the evidence for ongoing TSHR expression in thyroid cancer metastases. Priorities for further research are highlighted.

DOI 10.1530/ERC-17-0010
Citations Scopus - 12Web of Science - 14
Co-authors Jonathan Paul, Roger Smith, Craig Gedye, Christopher W Rowe
2017 Sugrue M, Maier R, Moore EE, Boermeester M, Catena F, Coccolini F, et al., 'Proceedings of resources for optimal care of acute care and emergency surgery consensus summit Donegal Ireland', WORLD JOURNAL OF EMERGENCY SURGERY, 12 (2017)
DOI 10.1186/s13017-017-0158-x
Citations Scopus - 8Web of Science - 8
2017 Di Saverio S, Biscardi A, Tugnoli G, Coniglio C, Gordini G, Bendinelli C, 'The Brave Challenge of NOM for Abdominal GSW Trauma and the Role of Laparoscopy As an Alternative to CT Scan', ANNALS OF SURGERY, 265 E37-E38 (2017)
DOI 10.1097/SLA.0000000000001301
Citations Scopus - 3Web of Science - 3
2017 Di Saverio S, Biscardi A, Tugnoli G, Coniglio C, Gordini G, Bendinelli C, 'The Brave Challenge of NOM for Abdominal GSW Trauma and the Role of Laparoscopy As an Alternative to CT Scan.', Annals of surgery, 265 e37-e38 (2017)
DOI 10.1097/sla.0000000000001301
2017 Bendinelli C, Cooper S, Evans T, Bivard A, Pacey D, Parson M, Balogh ZJ, 'Perfusion Abnormalities are Frequently Detected by Early CT Perfusion and Predict Unfavourable Outcome Following Severe Traumatic Brain Injury', World Journal of Surgery, 41 2512-2520 (2017) [C1]

© 2017, Société Internationale de Chirurgie. Background: In patients with severe traumatic brain injury (TBI), early CT perfusion (CTP) provides additional information beyond the ... [more]

© 2017, Société Internationale de Chirurgie. Background: In patients with severe traumatic brain injury (TBI), early CT perfusion (CTP) provides additional information beyond the non-contrast CT (NCCT) and may alter clinical management. We hypothesized that this information may prognosticate functional outcome. Methods: Five-year prospective observational study was performed in a level-1 trauma centre on consecutive severe TBI patients. CTP (obtained in conjunction with first routine NCCT) was interpreted as: abnormal, area of altered perfusion more extensive than on NCCT, and the presence of ischaemia. Six months Glasgow Outcome Scale-Extended of four or less was considered an unfavourable outcome. Logistic regression analysis of CTP findings and core variables [preintubation Glasgow Coma Scale (GCS), Rotterdam score, base deficit, age] was conducted using Bayesian model averaging to identify the best predicting model for unfavourable outcome. Results: Fifty patients were investigated with CTP (one excluded for the absence of TBI) [male: 80%, median age: 35 (23¿55), prehospital intubation: 7 (14.2%); median GCS: 5 (3¿7); median injury severity score: 29 (20¿36); median head and neck abbreviated injury scale: 4 (4¿5); median days in ICU: 10 (5¿15)]. Thirty (50.8%) patients had an unfavourable outcome. GCS was a moderate predictor of unfavourable outcome (AUC¿=¿0.74), while CTP variables showed greater predictive ability (AUC for abnormal CTP¿=¿0.92; AUC for area of altered perfusion more extensive than NCCT¿=¿0.83; AUC for the presence of ischaemia¿=¿0.81). Conclusion: Following severe TBI, CTP performed at the time of the first follow-up NCCT, is a non-invasive and extremely valuable tool for early outcome prediction. The potential impact on management and its cost effectiveness deserves to be evaluated in large-scale studies. Level of evidence III: Prospective study.

DOI 10.1007/s00268-017-4030-7
Citations Scopus - 4Web of Science - 5
Co-authors Andrew Bivard, Mark Parsons, Zsolt Balogh
2016 Di Saverio S, Birindelli A, Kelly MD, Catena F, Weber DG, Sartelli M, et al., 'WSES Jerusalem guidelines for diagnosis and treatment of acute appendicitis.', World J Emerg Surg, 11 34 (2016) [C1]
DOI 10.1186/s13017-016-0090-5
Citations Scopus - 153Web of Science - 144
Co-authors Zsolt Balogh
2016 Rowe CW, Bendinelli C, McGrath S, 'Charting a course through the CEAs: diagnosis and management of medullary thyroid cancer', Clinical Endocrinology, 85 340-343 (2016) [C3]
DOI 10.1111/cen.13114
Citations Scopus - 1Web of Science - 1
Co-authors Christopher W Rowe
2016 Ansaloni L, Pisano M, Coccolini F, Peitzmann AB, Fingerhut A, Catena F, et al., '2016 WSES guidelines on acute calculous cholecystitis (vol 11, 25, 2016)', WORLD JOURNAL OF EMERGENCY SURGERY, 11 (2016)
DOI 10.1186/s13017-016-0088-z
Citations Scopus - 4Web of Science - 3
Co-authors Zsolt Balogh
2016 Ansaloni L, Pisano M, Coccolini F, Peitzmann AB, Fingerhut A, Catena F, et al., '2016 WSES guidelines on acute calculous cholecystitis', WORLD JOURNAL OF EMERGENCY SURGERY, 11 (2016) [C1]
DOI 10.1186/s13017-016-0082-5
Citations Scopus - 86Web of Science - 81
Co-authors Zsolt Balogh
2015 Pereira BMT, Chiara O, Ramponi F, Weber DG, Cimbanassi S, De Simone B, et al., 'WSES position paper on vascular emergency surgery', WORLD JOURNAL OF EMERGENCY SURGERY, 10 (2015) [C1]
DOI 10.1186/s13017-015-0037-2
Citations Scopus - 6Web of Science - 5
2014 Sartelli M, Catena F, Ansaloni L, Coccolini F, Corbella D, Moore EE, et al., 'Complicated intra-abdominal infections worldwide: The definitive data of the CIAOW Study', World Journal of Emergency Surgery, 9 (2014) [C1]

The CIAOW study (Complicated intra-abdominal infections worldwide observational study) is a multicenter observational study underwent in 68 medical institutions worldwide during a... [more]

The CIAOW study (Complicated intra-abdominal infections worldwide observational study) is a multicenter observational study underwent in 68 medical institutions worldwide during a six-month study period (October 2012-March 2013). The study included patients older than 18 years undergoing surgery or interventional drainage to address complicated intra-abdominal infections (IAIs).1898 patients with a mean age of 51.6 years (range 18-99) were enrolled in the study. 777 patients (41%) were women and 1,121 (59%) were men. Among these patients, 1,645 (86.7%) were affected by community-acquired IAIs while the remaining 253 (13.3%) suffered from healthcare-associated infections. Intraperitoneal specimens were collected from 1,190 (62.7%) of the enrolled patients.827 patients (43.6%) were affected by generalized peritonitis while 1071 (56.4%) suffered from localized peritonitis or abscesses.The overall mortality rate was 10.5% (199/1898).According to stepwise multivariate analysis (PR = 0.005 and PE = 0.001), several criteria were found to be independent variables predictive of mortality, including patient age (OR = 1.1; 95%CI = 1.0-1.1; p < 0.0001), the presence of small bowel perforation (OR = 2.8; 95%CI = 1.5-5.3; p < 0.0001), a delayed initial intervention (a delay exceeding 24 hours) (OR = 1.8; 95%CI = 1.5-3.7; p < 0.0001), ICU admission (OR = 5.9; 95%CI = 3.6-9.5; p < 0.0001) and patient immunosuppression (OR = 3.8; 95%CI = 2.1-6.7; p < 0.0001). © 2014 Sartelli et al.; licensee BioMed Central Ltd.

DOI 10.1186/1749-7922-9-37
Citations Scopus - 118Web of Science - 103
Co-authors Zsolt Balogh
2014 Weber DG, Bendinelli C, Balogh ZJ, 'Damage control surgery for abdominal emergencies', British Journal of Surgery, 101 (2014) [C1]

Background: Damage control surgery is a management sequence initiated to reduce the risk of death in severely injured patients presenting with physiological derangement. Damage co... [more]

Background: Damage control surgery is a management sequence initiated to reduce the risk of death in severely injured patients presenting with physiological derangement. Damage control principles have emerged as an approach in non-trauma abdominal emergencies in order to reduce mortality compared with primary definitive surgery. Methods: A PubMed/MEDLINE literature review was conducted of data available over the past decade (up to August 2013) to gain information on current understanding of damage control surgery for abdominal surgical emergencies. Future directions for research are discussed. Results: Damage control surgery facilitates a strategy for life-saving intervention for critically ill patients by abbreviated laparotomy with subsequent reoperation for delayed definitive repair after physiological resuscitation. The six-phase strategy (including damage control resuscitation in phase 0) is similar to that for severely injured patients, although non-trauma indications include shock from uncontrolled haemorrhage or sepsis. Minimal evidence exists to validate the benefit of damage control surgery in general surgical abdominal emergencies. The collective published experience over the past decade is limited to 16 studies including a total of 455 (range 3-99) patients, of which the majority are retrospective case series. However, the concept has widespread acceptance by emergency surgeons, and appears a logical extension from pathophysiological principles in trauma to haemorrhage and sepsis. The benefits of this strategy depend on careful patient selection. Damage control surgery has been performed for a wide range of indications, but most frequently for uncontrolled bleeding during elective surgery, haemorrhage from complicated gastroduodenal ulcer disease, generalized peritonitis, acute mesenteric ischaemia and other sources of intra-abdominal sepsis. Conclusion: Damage control surgery is employed in a wide range of abdominal emergencies and is an increasingly recognized life-saving tactic in emergency surgery performed on physiologically deranged patients. © 2013 BJS Society Ltd.

DOI 10.1002/bjs.9360
Citations Scopus - 98Web of Science - 84
Co-authors Zsolt Balogh
2013 Bendinelli C, Bivard A, Nebauer S, Parsons MW, Balogh ZJ, 'Brain CT perfusion provides additional useful information in severe traumatic brain injury', INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 44 1208-1212 (2013) [C1]
DOI 10.1016/j.injury.2013.03.039
Citations Scopus - 10Web of Science - 13
Co-authors Andrew Bivard, Mark Parsons, Zsolt Balogh
2013 Sartelli M, Catena F, Ansaloni L, Moore E, Malangoni M, Velmahos G, et al., 'Complicated intra-abdominal infections in a worldwide context: an observational prospective study (CIAOW Study)', WORLD JOURNAL OF EMERGENCY SURGERY, 8 (2013) [C1]
DOI 10.1186/1749-7922-8-1
Citations Scopus - 32Web of Science - 34
Co-authors Zsolt Balogh
2013 Sartelli M, Viale P, Catena F, Ansaloni L, Moore E, Malangoni M, et al., '2013 WSES guidelines for management of intra-abdominal infections', WORLD JOURNAL OF EMERGENCY SURGERY, 8 (2013) [C2]
DOI 10.1186/1749-7922-8-3
Citations Scopus - 150Web of Science - 127
Co-authors Zsolt Balogh
2013 Sisak K, Manolis M, Hardy BM, Enninghorst N, Bendinelli C, Balogh ZJ, 'Acute transfusion practice during trauma resuscitation: Who, when, where and why?', INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 44 581-586 (2013) [C1]
DOI 10.1016/j.injury.2012.08.031
Citations Scopus - 24Web of Science - 19
Co-authors Zsolt Balogh
2013 Soederlund T, Yoshino O, Bendinelli C, Enninghorst N, Balogh ZJ, 'Acute repair of traumatic abdominal muscle avulsion from iliac crest: A mesh-free technique using suture anchors', INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 44 1257-1259 (2013) [C3]
DOI 10.1016/j.injury.2013.03.028
Citations Scopus - 1Web of Science - 1
Co-authors Zsolt Balogh
2013 Bendinelli C, Nebauer S, Tuan Q, Mcgrath S, Acharya S, 'Is minimally invasive parathyroid surgery an option for patients with gestational primary hyperparathyroidism?', BMC PREGNANCY AND CHILDBIRTH, 13 (2013) [C2]
DOI 10.1186/1471-2393-13-130
Citations Scopus - 5Web of Science - 6
2013 Di Saverio S, Coccolini F, Galati M, Smerieri N, Biffl WL, Ansaloni L, et al., 'Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2013 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group', WORLD JOURNAL OF EMERGENCY SURGERY, 8 (2013) [C1]
DOI 10.1186/1749-7922-8-42
Citations Scopus - 110Web of Science - 106
2012 Raychaudhuri P, Cheung NK, Bendinelli C, Puvaneswary M, Ferch R, Kumar R, 'Seatbelt: A Double-Edged Sword', CASE REPORTS IN PEDIATRICS, (2012)
DOI 10.1155/2012/326936
2012 Easton RM, Bendinelli C, Sisak K, Enninghorst N, Regan D, Evans J, Balogh ZJ, 'Recalled pain scores are not reliable after acute trauma', Injury: International Journal of the Care of the Injured, 43 1029-1032 (2012) [C1]
Citations Scopus - 4Web of Science - 3
Co-authors Zsolt Balogh
2012 Bendinelli C, Easton RM, Parr M, 'Focused assessment with sonography for trauma (FAST) after successful cardiopulmonary resuscitation', Resuscitation, 83 E17 (2012) [C3]
Citations Scopus - 3Web of Science - 4
2012 Alrahbi R, Easton RM, Bendinelli C, Enninghorst N, Sisak K, Balogh ZJ, 'Intercostal catheter insertion: Are we really doing well?', ANZ Journal of Surgery, 82 392-394 (2012) [C1]
Citations Scopus - 13Web of Science - 13
Co-authors Zsolt Balogh
2012 Ramponi F, Meredith GT, Bendinelli C, Soderlund T, 'Operative management of flail chest with anatomical locking plates (MatrixRib)', ANZ Journal of Surgery, 82 658-659 (2012) [C3]
Citations Scopus - 2Web of Science - 2
2012 Bendinelli C, Martin A, Nebauer SD, Balogh ZJ, 'Strangulated intercostal liver herniation subsequent to blunt trauma. First report with review of the world literature', World Journal of Emergency Surgery, 7 23 (2012) [C3]
Citations Scopus - 11Web of Science - 12
Co-authors Zsolt Balogh
2012 Easton RM, Bendinelli C, Sisak K, Enninghorst N, Balogh ZJ, 'Prehospital nausea and vomiting after trauma: Prevalence, risk factors, and development of a predictive scoring system', Journal of Trauma and Acute Care Surgery, 72 1249-1253 (2012) [C1]
Citations Scopus - 4Web of Science - 4
Co-authors Zsolt Balogh
2011 Sisak K, Dewar D, Butcher N, King K, Evans J, Miller M, et al., 'The treatment of traumatic shock: Recent advances and unresolved questions', European Journal of Trauma and Emergency Surgery, 37 567-575 (2011) [C1]
Citations Scopus - 2Web of Science - 1
Co-authors Zsolt Balogh
2011 Nolan GJ, Bendinelli C, Gani J, 'Laparoscopic drainage of an intramural duodenal haematoma: a novel technique and review of the literature', WORLD JOURNAL OF EMERGENCY SURGERY, 6 (2011)
DOI 10.1186/1749-7922-6-42
Citations Scopus - 11Web of Science - 11
Co-authors Jonathan Gani
2009 Bendinelli C, 'Effects of Land Mines and Unexploded Ordnance on the Pediatric Population and Comparison with Adults in Rural Cambodia', WORLD JOURNAL OF SURGERY, 33 1070-1074 (2009)
DOI 10.1007/s00268-009-9978-5
Citations Scopus - 22Web of Science - 17
2008 Bendinelli C, Balogh ZJ, 'Postinjury thromboprophylaxis', Current Opinion in Critical Care, 14 673-678 (2008) [C1]
DOI 10.1097/mcc.0b013e3283196538
Citations Scopus - 17Web of Science - 11
Co-authors Zsolt Balogh
2008 Balogh ZJ, Bendinelli C, Pollitt T, Kozar RA, Moore FA, 'Postinjury primary abdominal compartment syndrome', European Journal of Trauma and Emergency Surgery, 34 369-377 (2008) [C1]
DOI 10.1007/s00068-008-8106-9
Citations Scopus - 2Web of Science - 2
Co-authors Zsolt Balogh
2002 Bendinelli C, Leal T, Moncade F, Dieng M, Toure CT, Miccoli P, 'Endoscopic surgery in Senegal - Benefits, costs, and limits', SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 16 1488-1492 (2002)
DOI 10.1007/s00464-001-9188-1
Citations Scopus - 17Web of Science - 16
2000 Miccoli P, Berti P, Bendinelli C, Conte M, Fasolini F, Martino E, 'Minimally invasive video-assisted surgery of the thyroid: a preliminary report', LANGENBECKS ARCHIVES OF SURGERY, 385 261-264 (2000)
DOI 10.1007/s004230000141
Citations Scopus - 104Web of Science - 83
1999 Miccoli P, Berti P, Puccini M, Bendinelli C, Conte M, Picone A, Marcocci C, '[Video-assisted parathyroidectomy: a series of 85 cases].', Chirurgie; memoires de l'Academie de chirurgie, 124 511-515 (1999)
DOI 10.1016/s0001-4001(00)88273-2
1999 Miccoli P, Berti P, Piccone A, Puccini M, Bendinelli C, 'Video-guided parathyroid dissection without insufflation.', ANNALES DE CHIRURGIE, 53 934-935 (1999)
Citations Web of Science - 2
1999 Iacconi P, Bendinelli C, Miccoli P, Bernini GP, 'A case of Cushing's syndrome due to adrenocortical carcinoma with recurrence 19 months after laparoscopic adrenalectomy - T. Ushiyama, K. Suzuki, S. Kageyama K. Fujita, Y. Oki and T. Yoshimi - J. Urol., 157 : 2239, 1997 and J. B. Nelson, L. R. Kavoussi and M. N. Walther - J. Urol., 159 : 1310, 1998', JOURNAL OF UROLOGY, 161 1580-1580 (1999)
DOI 10.1016/S0022-5347(05)68968-9
Citations Web of Science - 16
1999 Miccoli P, Berti P, Puccini M, Bendinelli C, Conte M, Picone A, Marcocci C, 'Video-assisted parathyroidectomy: A series of 85 cases', Chirurgie, 124 511-515 (1999)

Aim of the study: To verify the feasibility of video-assisted parathyroidectomy, set up the indications and report the results in a series of 85 patients. Material and methods: Fr... [more]

Aim of the study: To verify the feasibility of video-assisted parathyroidectomy, set up the indications and report the results in a series of 85 patients. Material and methods: From 1997 to 1999, 85 patients affected by primary hyperparathyroidism due to single gland disease, with an adenoma smaller than 35 mm as demonstrated by preoperative imaging, were referred for video-assisted parathyroidectomy. There were 62 females and 23 males. Mean age was 53 years, (range 23-82). Video-assisted parathyroidectomy was associated with intra-operative PTH quick-assay. Calcium testing was controlled before leaving the hospital, 1 month and 3 months later, and postoperative laryngoscopy was performed in all patients. Results: There were five conversions to open cervicotomy: three due to a contra-lateral second adenoma, two because of an intrathyroidal adenoma. The mean operative time for video-assisted procedure was 59 minutes (range: 25-180). Circulating PTH levels 10 minutes after the removal of the affected gland(s) always dropped significantly, and pathological report confirmed the parathyroid nature of the specimens (mean diameter 13 mm, range 7-35). Morbidity consisted of five cases of transient hypocalcemia and one permanent laryngeal nerve paralysis. We registered no persistent or recurrent disease (mean follow-up 12.8 months, range 1-28). Conclusions: Video-assisted parathyroidectomy is feasible, and its results are similar to those of traditional procedure, while it seems superior as regards postoperative course and aesthetic results. It also allows different strategical decisions even during operation (i.e. bilateral exploration or thyroid lobectomy) by the same approach.

DOI 10.1016/S0001-4001(00)88273-2
Citations Scopus - 12
1999 Miccoli P, Berti P, Picone A, Puccini M, Bendinelli C, Gougard P, 'Video-guided parathyroid dissection without insufflation [2] (multiple letters)', Annales de Chirurgie, 53 934-935 (1999)
Citations Scopus - 3
1999 Ushiyama T, Suzuki K, Kageyama S, Fujita K, Oki Y, Yoshimi T, et al., 'Re: A case of Cushing's syndrome due to adrenocortical carcinoma with recurrence 19 months after laparoscopic adrenalectomy [1] (multiple letters)', Journal of Urology, 161 1580-1581 (1999)
DOI 10.1016/s0022-5347(05)68969-0
Citations Scopus - 2
1999 Bernini G, Moretti A, Lonzi S, Bendinelli C, Miccoli P, Salvetti A, 'Renin-angiotensin-aldosterone system in primary hyperparathyroidism before and after surgery', METABOLISM-CLINICAL AND EXPERIMENTAL, 48 298-300 (1999)
DOI 10.1016/S0026-0495(99)90075-6
Citations Scopus - 32Web of Science - 25
1999 Miccoli P, Bendinelli C, Berti P, Vignali E, Pinchera A, Marcocci C, 'Video-assisted versus conventional parathyroidectomy in primary hyperparathyroidism: A prospective randomized study', SURGERY, 126 1117-1121 (1999)
DOI 10.1067/msy.2099.102269
Citations Scopus - 194Web of Science - 156
1999 Monchik JM, Bendinelli C, Passero MA, Roggin KK, 'Subcutaneous forearm transplantation of autologous parathyroid tissue in patients with renal hyperparathyroidism', SURGERY, 126 1152-1158 (1999)
DOI 10.1067/msy.2099.101427
Citations Scopus - 27Web of Science - 20
1999 Miccoli P, Berti P, Conte M, Bendinelli C, Marcocci C, 'Minimally invasive surgery for thyroid small nodules: Preliminary report', JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 22 849-851 (1999)
DOI 10.1007/BF03343657
Citations Scopus - 226Web of Science - 198
1999 Iacconi P, Bendinelli C, Miccoli P, 'Endoscopic thyroid and parathyroid surgery', SURGICAL ENDOSCOPY-ULTRASOUND AND INTERVENTIONAL TECHNIQUES, 13 314-314 (1999)
DOI 10.1007/s004649900976
Citations Scopus - 7Web of Science - 8
1998 Miccoli P, Bendinelli C, Cecchini GM, Mazzeo S, Picone A, Pinchera A, Marcocci C, 'Endoscopic parathyroidectomy using a gasless procedure', BRITISH JOURNAL OF SURGERY, 85 1300-1300 (1998)
1998 Bendinelli C, Materazzi G, Puccini M, Iacconi P, Buccianti P, Miccoli P, '[Laparoscopic adrenalectomy. A retrospective comparison with traditional methods]', Minerva chirurgica, 53 871-875 (1998)
1998 Bendinelli C, Materazzi G, Puccini M, Iacconi P, Buccianti P, Miccoli P, 'Laparoscopic adrenalectomy. A retrospective comparison with traditional techniques', Minerva Chirurgica, 53 871-875 (1998)

Background. After 3 years from the introduction of laparoscopic adrenalectomy in an endocrine surgery unit the results are retrospectively compared with those achieved by traditio... [more]

Background. After 3 years from the introduction of laparoscopic adrenalectomy in an endocrine surgery unit the results are retrospectively compared with those achieved by traditional techniques with the aim of comparing the respective advantages. Methods. During this period 68 laparoscopic adrenalectomies have been performed. The main pre-, intra- e postoperative parameters of the adrenalectomies for benign neoplasm have been examined. Mean follow-up was 51 months (65.3 for open adrenalectomy and 18.8 for laparoscopic). Results. Statistical studies were homogeneous between the two groups. The laparoscopic adrenalectomy - with the same effectiveness - thanks to less peritoneum and parietal stress, is followed by fewer postoperative complications, faster resumption of biological functions, earlier return to work and better cosmetical results. Conclusions. On the basis of our personal experience laparoscopic adrenalectomy is to be considered the treatment of choice in the majority of adrenal benign neoplasms.

Citations Scopus - 11
1998 Miccoli P, Bendinelli C, Vignali E, Mazzeo S, Cecchini GM, Pinchera A, Marcocci C, 'Endoscopic parathyroidectomy: Report of an initial experience', SURGERY, 124 1077-1079 (1998)
DOI 10.1067/msy.1998.92006
Citations Scopus - 145Web of Science - 115
1998 Miccoli P, Bendinelli C, Monzani F, 'Surgical aspects of thyroid nodules previously treated by ethanol injection', EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, 106 S75-S77 (1998)
DOI 10.1055/s-0029-1212063
Citations Scopus - 6Web of Science - 3
1998 Bendinelli C, Lucchi M, Buccianti P, Iacconi P, Angeletti CA, Miccoli P, 'Adrenal masses in non-small cell lung carcinoma patients: Is there any role for laparoscopic procedures?', JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES-PART A, 8 119-124 (1998)
DOI 10.1089/lap.1998.8.119
Citations Scopus - 32Web of Science - 23
1998 Miccoli P, Bendinelli C, Conte M, Pinchera A, Marcocci C, 'Endoscopic parathyroidectomy by a gasless approach', JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES-PART A, 8 189-194 (1998)
DOI 10.1089/lap.1998.8.189
Citations Scopus - 108Web of Science - 93
1997 Miccoli P, Pinchera A, Cecchini G, Conte M, Bendinelli C, Vignali E, et al., 'Minimally invasive, video-assisted parathyroid surgery for primary hyperparathyroidism', JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 20 429-430 (1997)
DOI 10.1007/BF03347996
Citations Scopus - 95Web of Science - 142
1997 Miccoli P, Pinchera A, Cecchini G, Conte M, Bendinelli C, Vignali E, et al., 'Minimally invasive, video-assisted parathyroid surgery for primary hyperparathyroidism', Journal of Endocrinological Investigation, 20 428-429 (1997)

A new video-assisted surgical procedure for treatment of primary hyperparathyroidism combined with intraoperative quick PTH measurement was developed. This procedure was successfu... [more]

A new video-assisted surgical procedure for treatment of primary hyperparathyroidism combined with intraoperative quick PTH measurement was developed. This procedure was successfully used in 6 patients with a single parathyroid adenoma preoperatively localized by neck ultrasound examination.

DOI 10.1007/bf03347996
Citations Scopus - 157
1997 Miccoli P, Bendinelli C, Materazzi G, Iacconi P, Buccianti P, 'Traditional versus laparoscopic surgery in the treatment of pheochromocytoma: A preliminary study', JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES-PART A, 7 167-171 (1997)
DOI 10.1089/lap.1997.7.167
Citations Scopus - 30Web of Science - 25
1996 Iacconi P, Antonelli A, Monzani F, Bendinelli C, Ricci E, Miccoli P, '[Postoperative organotherapy for multinodular goiter]', Annali italiani di chirurgia, 67 347-350 (1996)
1996 Iacconi P, Aldi R, Bucceri R, Bendinelli C, Barsotti F, Miccoli P, '[Total colectomy with ileorectal anastomosis (IRA): our experience in 57 patients]', Il Giornale di chirurgia, 17 231-234 (1996)
1996 Iacconi P, Aldi R, Bucceri R, Bendinelli C, Barsotti F, Miccoli P, 'Total colectomy with ileorectal anastomosis (IRA): our experience in 57 patients', Il Giornale di chirurgia, 17 231-234 (1996)

Total colectomy with IRA in ulcerative colitis, Crohn&apos;s disease, familial polyposis and multicentric colonic cancer is still debated. In this paper the Authors present their ... [more]

Total colectomy with IRA in ulcerative colitis, Crohn's disease, familial polyposis and multicentric colonic cancer is still debated. In this paper the Authors present their experience with a retrospective review of 57 patients, treated in the Surgical Department of Pisa's University from 1978 to 1990. Through the results obtained, it is concluded that total colectomy with IRA is a valid procedure in the treatment of multiple polyposis, but must be associated with a long and careful follow up using fulguration for local recurrence. The usefulness of this treatment in multicentric colonic cancer is confirmed. However, the use of IRA in ulcerative colitis is debatable. This series shows the failure of colectomy with IRA in patients with Crohn's disease, due to the high incidence of local recurrences requiring reoperation.

Citations Scopus - 1
1996 Iacconi P, Antonelll A, Monzani F, Bendinelli C, Ricci E, Miccoli P, 'Levothyroxine suppressive therapy after surgery for multinodular goitre', Annali Italiani di Chirurgia, 67 347-350 (1996)

Post-operative therapy with L-Tiroxine can have a suppressive or substitutional aim. After a total thyroidectomy the patients need a substitutional therapy, while after subtotal t... [more]

Post-operative therapy with L-Tiroxine can have a suppressive or substitutional aim. After a total thyroidectomy the patients need a substitutional therapy, while after subtotal thyroidectomy the aim of the therapy is to suppress the TSH secretion. In the second case we want either to avoid the recurrence, either to give the hormones that residual gland cannot produce. The drug of choice is L-Tiroxine for both suppressive o substitutional therapy: There is a difference in dosage, that must be greater in first case. While there are some doubts in the littérature on the success of the suppressive therapy, we believe that there is enought evidence of his utility.

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Conference (7 outputs)

Year Citation Altmetrics Link
2018 Ferreira D, Gao M, Vilayur E, Bendinelli C, Sankoorikal C, 'HUNGRY BONE SYNDROME FOLLOWING PARATHYROIDECTOMY IN PATIENTS WITH END STAGE RENAL FAILURE', NEPHROLOGY DIALYSIS TRANSPLANTATION, Copenhagen, DENMARK (2018)
2018 Kuehn J, Rowe CW, Amico F, Ward A, Bendinelli C, 'Management of an intrathyroidal cystic parathyroid gland with post-traumatic haemorrhagic transformation causing acute airway compromise', Adelaide, Australia (2018)
Co-authors Christopher W Rowe
2018 Croker E, Chew C, Weigner J, Bendinelli C, McGrath S, Rowe CW, 'The whole is greater than the sum of its parts: synthesised triple-assessment of thyroid nodules optimises pre-operative risk-stratification.', Adeladie (2018)
Co-authors Christopher W Rowe
2011 Sisak K, Balogh ZJ, Bendinelli C, Enninghorst N, 'Acute transfusion practice during trauma resuscitation: Who, when and why?', ANZ Journal of Surgery, Adelaide, SA (2011) [E3]
Co-authors Zsolt Balogh
2011 Easton RM, Bendinelli C, Enninghorst N, Sisak K, Regan D, Balogh ZJ, 'Prehospital nausea and vomiting revisited', ANZ Journal of Surgery, Adelaide, SA (2011) [E3]
Co-authors Zsolt Balogh
2011 Easton RM, Bendinelli C, Powell A, Enninghorst N, Sisak K, Binks D, Balogh ZJ, 'Recall of pain after acute trauma', ANZ Journal of Surgery, Adelaide, SA (2011) [E3]
Co-authors Zsolt Balogh
2011 Alrahbri R, Bendinelli C, Sisak K, Enninghorst N, Balogh ZJ, 'Intercostal catheter insertion: Are we really doing well?', ANZ Journal of Surgery, Adelaide, SA (2011) [E3]
Co-authors Zsolt Balogh
Show 4 more conferences
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Dr Cino Bendinelli

Position

Conjoint Professor
School of Medicine and Public Health
Faculty of Health and Medicine

Contact Details

Email cino.bendinelli@newcastle.edu.au
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