2023 |
Samaranayake S, Barker D, Windsor A, 'Optimal cancer care pathways - the ideal versus reality for patient-centric cancer care during COVID-19', AUSTRALIAN HEALTH REVIEW, 47 472-479 (2023) [C1]
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Nova |
2023 |
Holliday EG, Weaver N, Barker D, Oldmeadow C, 'Adaptations to clinical trials in health research: a guide for clinical researchers', MEDICAL JOURNAL OF AUSTRALIA, 218 451-454 (2023)
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2023 |
Woolard A, Benders T, Campbell LE, Whalen OM, Mallise C, Karayanidis F, et al., 'The relationship between pitch contours in infant-directed speech and early signs of autism in infancy.', Infant Behav Dev, 72 101860 (2023) [C1]
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Nova |
2023 |
Kiross G, Chojenta C, Barker D, Loxton D, 'Health-seeking behaviour of Ethiopian caregivers when infants are unwell: a descriptive qualitative study.', BMJ Open, 13 e051462 (2023) [C1]
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Nova |
2023 |
Russo MA, Volschenk W, Bailey D, Santarelli DM, Holliday E, Barker D, et al., 'A Novel, Paresthesia-Free Spinal Cord Stimulation Waveform for Chronic Neuropathic Low Back Pain: Six-Month Results of a Prospective, Single-Arm, Dose-Response Study.', Neuromodulation : journal of the International Neuromodulation Society, 26 1412-1423 (2023) [C1]
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Nova |
2023 |
Ajitsaria P, Lott N, Baker A, Lacey J, Magnusson M, Douglas JL, et al., 'Protocol paper for SMART OPS: Shared decision-making Multidisciplinary Approach - a Randomised controlled Trial in the Older adult Population considering Surgery', BMJ OPEN, 13 (2023)
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2023 |
Jackson MA, Brown AL, Baker AL, Bonevski B, Haber P, Bonomo Y, et al., 'Tobacco treatment incorporating contingency management, nicotine replacement therapy, and behavioral counseling for pregnant women who use substances: a feasibility trial.', Front Psychiatry, 14 1207955 (2023) [C1]
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Nova |
2022 |
Robijn AL, Bokern MP, Jensen ME, Barker D, Baines KJ, Murphy VE, 'Risk factors for asthma exacerbations during pregnancy: a systematic review and meta-analysis', EUROPEAN RESPIRATORY REVIEW, 31 (2022) [C1]
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Nova |
2022 |
Woolard A, Lane AE, Campbell LE, Whalen OM, Swaab L, Karayanidis F, et al., 'Infant and Child-Directed Speech Used with Infants and Children at Risk or Diagnosed with Autism Spectrum Disorder: a Scoping Review', Review Journal of Autism and Developmental Disorders, 9 290-306 (2022) [C1]
Infants diagnosed with autism spectrum disorder (autism) have difficulty engaging in social communication and interactions with others and often experience language impairment. Th... [more]
Infants diagnosed with autism spectrum disorder (autism) have difficulty engaging in social communication and interactions with others and often experience language impairment. The use of infant-directed speech (IDS), which is the speech register used when interacting with infants, is associated with infant language and socio-communicative development. The aim of this study was twofold; the first aim was to scope the literature to determine if evidence exists for differences between the IDS caregivers use to infants at high-risk or those later diagnosed with autism, and the IDS typically spoken to neurotypical infants. The second aim was to investigate if any IDS characteristics used by caregivers of high-risk or diagnosed infant populations predicted language development. Twenty-six studies were included and provided evidence that high-risk and later diagnosed infants are exposed to similar amounts of IDS as their neurotypical peers. There is evidence, however, that the IDS used with high-risk and later diagnosed infants may comprise shorter utterances, more action-directing content, fewer questions, more attention bids, and more follow-in commenting. There is also evidence that more attention bids and follow-in commenting used to infants at high risk or those later diagnosed with autism were associated with better language abilities longitudinally.
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Nova |
2022 |
Howard BC, McRobbie H, Petrie D, Barker D, Mendelsohn C, Anderson J, et al., 'Effectiveness, safety and cost-effectiveness of vaporized nicotine products versus nicotine replacement therapy for tobacco smoking cessation in a low-socioeconomic status Australian population: a study protocol for a randomized controlled trial', TRIALS, 23 (2022)
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2022 |
Baker AL, McCarter K, Brophy L, Castle D, Kelly PJ, Cocks N, et al., 'Adapting Peer Researcher Facilitated Strategies to Recruit People Receiving Mental Health Services to a Tobacco Treatment Trial', FRONTIERS IN PSYCHIATRY, 13 (2022) [C1]
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Nova |
2022 |
Miller P, Vakidis T, Taylor N, Baker T, Stella J, Egerton-Warburton D, et al., 'Most common principal diagnoses assigned to Australian emergency department presentations involving alcohol use: a multi-centre study', AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH, 46 903-909 (2022) [C1]
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Nova |
2022 |
Bokern MP, Robijn AL, Jensen ME, Barker D, Baines KJ, Murphy VE, 'Risk factors for asthma exacerbation during pregnancy: protocol for a systematic review and meta-analysis', SYSTEMATIC REVIEWS, 11 (2022)
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2022 |
Robinson KJ, Lubans DR, Mavilidi MF, Hillman CH, Benzing V, Valkenborghs SR, Barker D, 'Effects of Classroom-Based Resistance Training With and Without Cognitive Training on Adolescents Cognitive Function, On-task Behavior, and Muscular Fitness', Frontiers in Psychology, 13 (2022) [C1]
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Nova |
2022 |
Barnes LAJ, Longman J, Adams C, Paul C, Atkins L, Bonevski B, et al., 'The MOHMQuit (Midwives and Obstetricians Helping Mothers to Quit Smoking) Trial: protocol for a stepped-wedge implementation trial to improve best practice smoking cessation support in public antenatal care services', IMPLEMENTATION SCIENCE, 17 (2022)
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2022 |
Tyagi S, Chan E-C, Barker D, McElduff P, Taylor KA, Riveros C, et al., 'Transcriptomic analysis reveals myometrial topologically associated domains linked to the onset of human term labour.', Mol Hum Reprod, 28 (2022) [C1]
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Nova |
2022 |
Sánchez-Ovando S, Pavlidis S, Kermani NZ, Baines KJ, Barker D, Gibson PG, et al., 'Pathways linked to unresolved inflammation and airway remodelling characterize the transcriptome in two independent severe asthma cohorts.', Respirology (Carlton, Vic.), 27 730-738 (2022) [C1]
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Nova |
2021 |
Bokern MP, Robijn AL, Jensen ME, Barker D, Callaway L, Clifton V, et al., 'Factors Associated with Asthma Exacerbations During Pregnancy', JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 9 4343-+ (2021) [C1]
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Nova |
2021 |
Niessen NM, Gibson PG, Baines KJ, Barker D, Yang IA, Upham JW, et al., 'Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment', ALLERGY, 76 2090-2101 (2021) [C1]
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Nova |
2021 |
Tenzin T, Karki R, Duba T, Jamphel K, Dhendup S, Subba DK, et al., 'Prevalence of drink-driving in Thimphu, Bhutan: Targeted surveillance at sentinel sites', Drug and Alcohol Review, 40 454-458 (2021) [C1]
Introduction and Aims: Bhutan has a high incidence of alcohol-related disease. With economic development, motorised transport is proliferating, increasing the potential for traffi... [more]
Introduction and Aims: Bhutan has a high incidence of alcohol-related disease. With economic development, motorised transport is proliferating, increasing the potential for traffic injury. We investigated drink-driving in the country's largest urban environment. Methods: Working with police, we set up checkpoints at major thoroughfares in Thimphu, on Tuesday, Friday and Saturday nights, from May to July 2017. Police directed cars to testing bays where drivers were breathalysed and interviewed. Results: All 1596 drivers stopped by police were breathalysed, and 212 (13%) tested positive. Blood alcohol of >0.02 g/dL (which we defined as ¿probable impairment¿) was detected in 178 drivers (11%), while 67 (4.2%) exceeded the legal limit of 0.08 g/dL. Probable impairment was more common in men, older drivers, on Tuesdays (versus Fridays or Saturdays) and later at night. Conclusion: Drink-driving is very common at night-time in Bhutan. Routine roadside random breath-testing, and media campaigns emphasising the risk of apprehension and consequent serious financial and social penalties, should be considered to deter drink-driving.
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Nova |
2021 |
Kiross GT, Chojenta C, Barker D, Loxton D, 'Individual-, household- and community-level determinants of infant mortality in Ethiopia', PLOS ONE, 16 (2021) [C1]
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Nova |
2021 |
Robijn AL, Barker D, Gibson PG, Giles WB, Clifton VL, Mattes J, et al., 'Factors Associated with Nonadherence to Inhaled Corticosteroids for Asthma During Pregnancy', JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 9 1242-+ (2021) [C1]
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Nova |
2021 |
Vyslysel G, Barker D, Hubbard IJ, 'The Canadian Occupational Performance Measure (COPM) as Routine Practice in Community-Based Rehabilitation: A Retrospective Chart Review.', Archives of rehabilitation research and clinical translation, 3 100134 (2021) [C1]
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Nova |
2021 |
Campbell MJ, Green D, Barker D, 'Understanding basic numbers: examples from Brexit, Covid and common medical conditions', Research Methods in Medicine & Health Sciences, 2 31-38 (2021) [C1]
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Nova |
2021 |
Pursey KM, Burrows TL, Barker D, Hart M, Paxton SJ, 'Disordered eating, body image concerns, and weight control behaviors in primary school aged children: A systematic review and meta-analysis of universal-selective prevention interventions', INTERNATIONAL JOURNAL OF EATING DISORDERS, 54 1730-1765 (2021) [C1]
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Nova |
2021 |
Shukla SD, Taylor SL, Gibson PG, Barker D, Upham JW, Yang IA, et al., 'Add-on azithromycin reduces sputum cytokines in non-eosinophilic asthma: an AMAZES substudy', THORAX, 76 733-736 (2021)
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2021 |
Paul CL, Warren G, Vinod S, Meiser B, Stone E, Barker D, et al., 'Care to Quit: a stepped wedge cluster randomised controlled trial to implement best practice smoking cessation care in cancer centres', IMPLEMENTATION SCIENCE, 16 (2021)
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2021 |
Kiross GT, Chojenta C, Barker D, Loxton D, 'Optimum maternal healthcare service utilization and infant mortality in Ethiopia.', BMC Pregnancy Childbirth, 21 390 (2021) [C1]
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Nova |
2021 |
Sanchez-Ovando S, Simpson JL, Barker D, Baines KJ, Wark PAB, 'Transcriptomics of biopsies identifies novel genes and pathways linked to neutrophilic inflammation in severe asthma', CLINICAL AND EXPERIMENTAL ALLERGY, 51 1279-1294 (2021) [C1]
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Nova |
2020 |
Tong K, Barker D, France M, Burr L, Greville H, Visser S, et al., 'Lumacaftor/ivacaftor reduces exacerbations in adults homozygous for Phe508del mutation with severe lung disease', Journal of Cystic Fibrosis, 19 415-420 (2020) [C1]
Background: Lumacaftor/ivacaftor (LUM/IVA) improves outcomes in cystic fibrosis (CF) patients homozygous for Phe508del with ppFEV1 > 40%. There is limited safety or efficacy da... [more]
Background: Lumacaftor/ivacaftor (LUM/IVA) improves outcomes in cystic fibrosis (CF) patients homozygous for Phe508del with ppFEV1 > 40%. There is limited safety or efficacy data in patients with ppFEV1 < 40%. We determined whether LUM/IVA in patients with ppFEV1 < 40 would reduce the rate of pulmonary exacerbations. Methods: This was a case control study performed on patients > 12 years, homozygous for Phe508del CFTR mutation and with ppFEV1 < 40%. Control subjects were matched for age, sex and ppFEV1, and had mutations ineligible for LUM/IVA. We assessed the rate of pulmonary exacerbations requiring intravenous antibiotics, the mean rate of change in ppFEV1 over 12 months and all adverse events. Results: Data was collected from 7 Australian CF centres on 105 patients; 72 on LUM/IVA and 33 controls. LUM/IVA demonstrated a large reduction in exacerbations with an incident rate ratio of 0.455 (95%CI; 0.306 ¿ 0.676), p < 0.001 after adjusting for the number of exacerbations in the previous 12 months. LUM/IVA prolonged the time to first exacerbation and reduced the rate of decline in ppFEV1 over 12 months. Adverse events were common; chest tightness or dyspnoea was experienced by 55% and resulted in cessation of treatment in 32%. Conclusions: Treatment with LUM/IVA resulted in a substantially lower rate of pulmonary exacerbations, prolonged time to first exacerbation and slowed the rate of decline of ppFEV1 in participants with severe lung disease. Adverse reactions to LUM/IVA however were unacceptably frequent, and resulted in a very high discontinuation rate.
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Nova |
2020 |
Kiross GT, Chojenta C, Barker D, Loxton D, 'The effects of health expenditure on infant mortality in sub-Saharan Africa: evidence from panel data analysis', HEALTH ECONOMICS REVIEW, 10 (2020) [C1]
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Nova |
2020 |
Sánchez-Ovando S, Baines KJ, Barker D, Wark PA, Simpson JL, 'Six gene and TH2 signature expression in endobronchial biopsies of participants with asthma', Immunity, Inflammation and Disease, 8 40-49 (2020) [C1]
Background: Both the six gene signature (6GS: CPA3, DNASE1L3, CLC, IL1B, ALPL, and CXCR2) and T-helper 2 signature (TH2S: CLCA1, SERPINB2, and POSTN) are proposed as biomarkers in... [more]
Background: Both the six gene signature (6GS: CPA3, DNASE1L3, CLC, IL1B, ALPL, and CXCR2) and T-helper 2 signature (TH2S: CLCA1, SERPINB2, and POSTN) are proposed as biomarkers in the identification of inflammatory phenotypes of asthma in induced sputum and epithelial brushings, respectively. The aim of this study was to explore patterns of gene expression of known signatures, 6GS and TH2S in endobronchial biopsies. Methods: This was an exploratory cross-sectional study of gene expression in endobronchial biopsies of 55 adults with asthma and 9 healthy controls (HC). The expression of the 6GS and TH2S was determined by quantitative polymerase chain reaction. Correlations with clinical and cellular characteristics were performed, and receiver operating characteristic was utilized to assess signatures' ability to predict asthma from HC and inflammatory phenotypes. Results: Gene expression of DNASE1L3 (P =.045) was upregulated in asthma compared with HC, and IL1B (P =.017) was upregulated in neutrophilic asthma compared with non-neutrophilic asthma. In asthma, the expression of CPA3 was negatively associated with ICS daily dose (r = -.339; P =.011), IL1B expression was positively associated with bronchial lavage fluid (BLF) total cell count (r =.340; P =.013) and both CLC and POSTN expression were associated with lymphocytes percentage in BLF (r = -.355, P =.009; r = -.300, P =.025, respectively). Both 6GS (area under curve [AUC] = 86.3%; P =.017) and TH2S (AUC = 72.7%; P =.037) could significantly predict asthma from HC. In addition, 6GS can identify neutrophilic (AUC = 93.2%; P =.005) and TH2S identifies eosinophilic (AUC = 62.7%; P =.033) asthma. Conclusions and Clinical Relevance: There was increased expression of DNASE1L3 in asthma and IL1B in neutrophilic asthma. These results show similar upregulated patterns of expression in two genes of the 6GS in endobronchial biopsies, previously identified in sputum. The upregulation of DNASE1L3 and IL1B suggests that common mechanisms may be at play throughout the airway.
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Nova |
2020 |
Plotnikoff RC, Stacey FG, Jansson AK, Ewald B, Johnson NA, Brown WJ, et al., 'Does Patient Preference for Mode of Intervention Delivery Impact Intervention Efficacy and Attrition?', American Journal of Health Promotion, 34 63-66 (2020) [C1]
Purpose: To explore whether there was a difference in objectively measured physical activity and study participation between people who received their preferred study group alloca... [more]
Purpose: To explore whether there was a difference in objectively measured physical activity and study participation between people who received their preferred study group allocation (matched) and those who did not receive their preferred study group (mismatched). Design: Secondary data from the NewCOACH randomized controlled trial. Setting: Insufficiently active patients in the primary care settings in Sydney and Newcastle, Australia. Participants: One hundred seventy-two adults aged 20 to 81 years. Intervention: Participants indicated their intervention preference at baseline for (1) five face-to-face visits with an exercise specialist, (2) one face-to-face visit and 4 telephone follow-ups with an exercise specialist, (3) written material, or (4) slight-to-no preference. Participants were then allocated to an intervention group and categorized as either ¿matched¿ or ¿mismatched¿ based on their indications. Participants who reported a slight-to-no preference was categorized as ¿matched.¿ Measures: Daily step count as measured by pedometers and study participation. Analysis: Mean differences between groups in daily step count at 3 and 12 months (multiple linear regression models) and study participation at baseline, 3 months, and 12 months (¿2 tests). Results: Preference for an intervention group prior to randomization did not significantly (all P¿s >.05 using 95% confidence interval) impact step counts (differences of <600 steps/day between groups) or study participation. Conclusion: Future research should continue to address whether the strength of preferences influence study outcome and participation and whether the study preferences change over time.
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Nova |
2020 |
Drovandi A, Salem S, Barker D, Booth D, Kairuz T, 'Human Biomarker Exposure from Cigarettes Versus Novel Heat-Not-Burn Devices: A Systematic Review and Meta-Analysis', Nicotine and Tobacco Research, 22 1077-1085 (2020) [C1]
Introduction: Novel tobacco products require independent research to assess their safety. This study assessed the current literature for trials comparing levels of biomarkers of e... [more]
Introduction: Novel tobacco products require independent research to assess their safety. This study assessed the current literature for trials comparing levels of biomarkers of exposure (BoE) between conventional cigarettes (CC) and heat-not-burn (HNB) devices. Methods: Ten databases were searched using terms including: "heat not burn,""iqos,""teeps,""mrtp,""tobacco heating,"and "glo"between January 1, 2010 and August 13, 2019. Randomized controlled trials (RCTs) assessing comparative BoE levels in humans using either CC or novel HNB devices were eligible. BoE were tabulated, and differences between the intervention and control groups were analyzed and combined using a random-effects meta-analysis. Results: Ten nonblinded, RCTs were eligible, involving a total of 1766 participants. Studies regularly reported on 12 BoE (including nicotine). HNB devices assessed included the "IQOS"and "glo"devices and "precursor"(being developed) HNB devices. In comparison to CC, all 12 BoEs assessed were significantly lower for participants assigned to an HNB device. In comparison to smoking abstinence, HNB devices were statistically equivalent for eight BoEs and significantly elevated for four BoEs. Conclusions: This review found that the potential for harm to humans is reduced when using HNB devices compared to CC as indicated by significant reductions in BoE levels. Whilst these results support tobacco manufacturer claims of improved safety, the small number of studies included, limited range of BoE assessed, and involvement of the tobacco industry necessitate further independent research to confirm the HNB devices as being a safer alternative to CC. Implications: This study supports claims made by tobacco manufacturers on the improved safety of HNB tobacco devices in comparison to CC. These novel devices lead to reduced exposure to key biomarkers, which are linked to the health consequences attributed to tobacco use. This has strong implications for international public health as well as further research and policy development relating to the safety aspects and legalities of novel tobacco products.
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Nova |
2020 |
Leahy AA, Mavilidi MF, Smith JJ, Hillman CH, Eather N, Barker D, Lubans DR, 'Review of High-Intensity Interval Training for Cognitive and Mental Health in Youth.', Medicine and science in sports and exercise, 52 2224-2234 (2020) [C1]
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Nova |
2019 |
Kiross GT, Chojenta C, Barker D, Tiruye TY, Loxton D, 'The effect of maternal education on infant mortality in Ethiopia: A systematic review and meta-analysis', PLoS ONE, 14 (2019) [C1]
Introduction Some studies in developing countries have shown that infant mortality is highly associated with maternal education, implying that maternal education might play an imp... [more]
Introduction Some studies in developing countries have shown that infant mortality is highly associated with maternal education, implying that maternal education might play an important role in the reduction of infant mortality. However, other research has shown that lower levels of maternal education does not have any significant contribution to infant survival. In this systematic review, we focus on the effect of different levels of maternal education on infant mortality in Ethiopia. Methods MEDLINE, EMBASE, CINAHL, Scopus, and Maternity and Infant Care databases were searched between November 15, 2017 and February 20, 2018. All articles published until February 20, 2018 were included in the study. The data extraction was conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA 2009) guidelines. An I2 test was used to assess heterogeneity and a funnel plot was used to check publication bias. Findings We retrieved 441 records after removing duplications. During screening, 31 articles were fully accessed for data extraction. Finally, five articles were included for analysis. The overall pooled estimate indicated that attending primary education was associated with a 28% reduction in the odds of infant mortality compared to those infants born to mothers who were illiterate, OR: 0.72 (95% CI = 0.66, 0.78). Another pooled estimate indicated that attending secondary education and above was associated with a 45% reduction in the odds of infant mortality compared to those infants born to mothers who were illiterate, OR: 0.55 (95% CI = 0.47, 0.64).
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Nova |
2019 |
Lokwani R, Wark PAB, Baines KJ, Barker D, Simpson JL, 'Hypersegmented airway neutrophils and its association with reduced lung function in adults with obstructive airway disease: An exploratory study', BMJ Open, 9 (2019) [C1]
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Nova |
2019 |
Miller P, Droste N, Egerton-Warburton D, Caldicott D, Fulde G, Ezard N, et al., 'Driving change: A partnership study protocol using shared emergency department data to reduce alcohol-related harm', EMERGENCY MEDICINE AUSTRALASIA, 31 942-947 (2019)
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2019 |
Williamson A, Barker D, Green S, D'Este C, Davies HTO, Jorm L, et al., 'Increasing the capacity of policy agencies to use research findings: a stepped-wedge trial', HEALTH RESEARCH POLICY AND SYSTEMS, 17 (2019) [C1]
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Nova |
2019 |
Fradgley EA, Boltong A, O'Brien L, Boyes AW, Lane K, Beattie A, et al., 'Implementing Systematic Screening and Structured Care for Distressed Callers Using Cancer Council's Telephone Services: Protocol for a Randomized Stepped-Wedge Trial', JMIR RESEARCH PROTOCOLS, 8 93-103 (2019)
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2019 |
Dundas K, Johnson NA, Paras L, Hancock S, Barker D, Chiu S, James EL, 'Does Increasing the Experiential Component Improve Efficacy of the This Is Public Health Photo Essay Task? A Nonrandomized Trial', Pedagogy in Health Promotion, 5 178-189 (2019) [C1]
Opportunities for evaluating experiential learning activities in tertiary public health education are growing. It has previously been shown that utilizing the ¿This is Public Heal... [more]
Opportunities for evaluating experiential learning activities in tertiary public health education are growing. It has previously been shown that utilizing the ¿This is Public Health¿ (TIPH) sticker campaign as an experiential photo essay task led to increased understanding of public health. Emerging mobile technologies such as geocaching, which provide an opportunity to increase the experiential component of the TIPH photo essay task, have not been evaluated. This study aimed to determine whether adding geocaching to the TIPH photo essay task increased the efficacy of learning about public health, when compared with the TIPH photo essay task alone. A two-arm nonrandomized trial was conducted with 785 allied health and preprofessional teaching students studying first-year public health courses. Students were allocated to either the TIPH photo essay task (n = 210) or the TIPH photo task plus geocaching (n = 92) according to the course they were enrolled into. The primary outcome was the quality of the definition of public health provided by students, which was assessed using the Definition of Public Health Rating Scale. Data were analyzed using a linear mixed model. Of 302 (39%) students who consented to participate, 212 (70%) provided baseline and follow-up data. After adjusting for baseline demographic differences, the geocaching group had improved knowledge of public health at follow-up according to the Definition of Public Health Rating Scale (increasing 0.29 units more than the traditional group; p =.03). As this increase in knowledge score is unlikely to be of practical significance, the additional burden of implementing geocaching may not be justified.
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Nova |
2019 |
Preece K, Ang M, Barker D, Craig A, Schultz A, Sinclair J, et al., 'Regional centres conduct food challenges with outcomes equivalent to a tertiary pediatric hospital', PEDIATRIC ALLERGY AND IMMUNOLOGY, 30 764-767 (2019) [C1]
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Nova |
2019 |
Dunn A, Marsden DL, Barker D, van Vliet P, Spratt NJ, Callister R, 'Evaluation of three measures of cardiorespiratory fitness in independently ambulant stroke survivors', Physiotherapy Theory and Practice, 35 622-632 (2019) [C1]
Measuring cardiorespiratory fitness (CRF) in the stroke population is challenging. Currently, the recommended method is a graded exercise test (GXT) on an ergometer such as a trea... [more]
Measuring cardiorespiratory fitness (CRF) in the stroke population is challenging. Currently, the recommended method is a graded exercise test (GXT) on an ergometer such as a treadmill or cycle, which may not always be possible. We investigated whether walking tests such as the six-minute walk test (6MWT) and the shuttle walk test (SWT) may be appropriate indicators of CRF in the stroke population. Twenty-three independently ambulant stroke survivors (11 men, age 61.5¿±¿18.4¿years) within one-year post stroke performed the 6MWT, SWT, and cycle GXT, during which peak oxygen consumption (VO2peak) and heart rate (HRpeak) were recorded. There were no differences (p¿>¿0.05) in mean VO2peak among the three tests (min-max: 17.08¿18.09¿mL¿kg-1¿min-1). For individuals, small discrepancies in VO2peak between the 6MWT and other tests were greater with higher fitness levels. HRpeak was significantly (p¿=¿0.005) lower during the 6MWT. Correlations between VO2peak and performance measures within each test were high (6MWT VO2peak and distance: r¿=¿0.78, SWT VO2peak and shuttles: r¿=¿0.73, cycle GXT VO2peak and workload: r¿=¿0.77) suggesting the performance measures may be clinically useful as proxy measures of CRF. Common comorbidities, such as lower-limb joint pain and poor balance, and participant¿s fastest walking speed, should inform the choice of CRF test.
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Nova |
2019 |
Berry J, Jacomb I, Lunn J, Sedwell A, Shakeshaft A, Kelly PJ, et al., 'A stepped wedge cluster randomised trial of a cognitive remediation intervention in alcohol and other drug (AOD) residential treatment services', BMC PSYCHIATRY, 19 (2019)
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2019 |
Boland VC, Mattick RP, Siahpush M, Barker D, Doran CM, Martire KA, et al., 'Factors associated with Quitline and pharmacotherapy utilisation among low-socioeconomic status smokers', Addictive Behaviors, 89 113-120 (2019) [C1]
Aims: To examine factors associated with Quitline and pharmacotherapy utilisation in low socioeconomic status (low-SES) smokers enrolled in a smoking cessation trial. Methods: Bas... [more]
Aims: To examine factors associated with Quitline and pharmacotherapy utilisation in low socioeconomic status (low-SES) smokers enrolled in a smoking cessation trial. Methods: Baseline data was used from a large-scale smoking cessation randomised controlled trial (RCT). Logistic regression models were used to examine predictors of treatment utilisation prior to entering the RCT and perceived effectiveness of past and future use. Results: A total of 1047 smokers consented and prior to enrolment 92% had previously tried to quit smoking, 86% had ever used quit support, 83% had used pharmacotherapy at least once and 38% had ever utilised Quitline. For those who had used pharmacotherapies, 71% used NRT, of which 21% had used dual NRT products. In the last 12-months, 27% utilised Quitline and 50% utilised NRT. Ever use of Quitline was negatively associated with self-efficacy to quit (OR: 0.80; 95% CI: 0.68, 0.94 p <.01) and positively associated with being diagnosed with a mental health condition (OR: 1.50; 95% CI: 1.01, 2.25 p <.05). Recent use of NRT was positively associated with mental health condition (OR: 1.39; 95% CI: 1.02, 1.90 p <.05) and negatively associated with alcohol consumption (OR: 0.69; 95% CI: 0.52, 0.92 p <.01). Conclusion: Past use of Quitline and pharmacotherapy treatment was associated with self-efficacy to quit, sociodemographic variables, mental health conditions and alcohol consumption. Community-based strategies that target smoking, mental health and drug and alcohol problems may overcome some of the barriers that prevent low-SES populations from engaging with smoking cessation support.
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Nova |
2019 |
Lokwani R, Wark PAB, Baines KJ, Fricker M, Barker D, Simpson JL, 'Blood neutrophils in copd but not asthma exhibit a primed phenotype with downregulated cd62l expression', International Journal of COPD, 14 2517-2525 (2019) [C1]
Purpose: To characterize neutrophils in obstructive airway disease by measuring their surface adhesion molecules and oxidative burst along with characterizing them into different ... [more]
Purpose: To characterize neutrophils in obstructive airway disease by measuring their surface adhesion molecules and oxidative burst along with characterizing them into different subsets as per their adhesion molecule expression. Patients and methods: Peripheral blood from adults with COPD (n=17), asthma (n=20), and healthy participants (n=19) was examined for expression of CD16, CD62L, CD11b, CD11c, and CD54, and analyzed by flow cytometry. For oxidative burst and CD62L shedding analysis, CD16 and CD62L stained leukocytes were loaded with Dihydrorhodamine-123 (DHR-123) and stimulated with N-Formylmethionine-leucyl-phenylalanine (fMLF). Neutrophil subsets were characterized based on CD16 and CD62L expression. Marker surface expression was recorded on CD16+ neutrophils as median fluorescence intensity (MFI). Results: Neutrophil surface expression of CD62L was significantly reduced in COPD (median (IQR) MFI: 1156 (904, 1365)) compared with asthma (1865 (1157, 2408)) and healthy controls (2079 (1054, 2960)); p=0.028. COPD neutrophils also demonstrated a significant reduction in CD62L expression with and without fMLF stimulation. Asthma participants had a significantly increased proportion and number of CD62Lbright/CD16dim neutrophils (median: 5.4% and 0.14 × 109/L, respectively), in comparison with healthy (3.54% and 0.12 × 109/L, respectively); p<0.017. Conclusion: Reduced CD62L expression suggests blood neutrophils have undergone priming in COPD but not in asthma, which may be the result of systemic inflammation. The increased shedding of CD62L receptor by COPD blood neutrophils suggests a high sensitivity for activation.
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Nova |
2018 |
Morten M, Collison A, Murphy VE, Barker D, Oldmeadow C, Attia J, et al., 'Managing Asthma in Pregnancy (MAP) trial: FENO levels and childhood asthma', Journal of Allergy and Clinical Immunology, 142 1765-1772.e4 (2018) [C1]
Background: The single-center double-blind, randomized controlled Managing Asthma in Pregnancy (MAP) trial in Newcastle, Australia, compared a treatment algorithm using the fracti... [more]
Background: The single-center double-blind, randomized controlled Managing Asthma in Pregnancy (MAP) trial in Newcastle, Australia, compared a treatment algorithm using the fraction of exhaled nitric oxide (FENO) in combination with asthma symptoms (FENO group) against a treatment algorithm using clinical symptoms only (clinical group) in pregnant asthmatic women (Australian New Zealand Clinical Trials Registry, no. 12607000561482). The primary outcome was a 50% reduction in asthma exacerbations during pregnancy in the FENO group. However, the effect of FENO-guided management on the development of asthma in the offspring is unknown. Objective: We sought to investigate the effect of FENO-guided asthma management during pregnancy on asthma incidence in childhood. Methods: A total of 179 mothers consented to participate in the Growing into Asthma (GIA) double-blind follow-up study with the primary aim to determine the effect of FENO-guided asthma management on childhood asthma incidence. Results: A total of 140 children (78%) were followed up at 4 to 6 years of age. FENO-guided as compared to symptoms-only approach significantly reduced doctor-diagnosed asthma (25.9% vs 43.2%; odds ratio [OR], 0.46, 95% CI, 0.22-0.96; P =.04). Furthermore, frequent wheeze (OR, 0.27; 95% CI, 0.09-0.87; P =.03), use of short-acting ß-agonists (OR, 0.49; 95% CI, 0.25-0.97; P =.04), and emergency department visits for asthma (OR, 0.17; 95% CI, 0.04-0.76; P =.02) in the past 12 months were less common in children born to mothers from the FENO group. Doctor-diagnosed asthma was associated with common risk alleles for early onset asthma at gene locus 17q21 (P =.01 for rs8069176; P =.03 for rs8076131), and higher airways resistance (P =.02) and FENO levels (P =.03). A causal mediation analysis suggested natural indirect effects of FENO-guided asthma management on childhood asthma through ¿any use¿ and ¿time to first change in dose¿ of inhaled corticosteroids during the MAP trial (OR: 0.83; 95% CI: 0.59-0.99, and OR: 0.90; 95% CI: 0.70-1.03, respectively). Conclusions: FENO-guided asthma management during pregnancy prevented doctor-diagnosed asthma in the offspring at preschool age, in part mediated through changes in use and dosing of inhaled corticosteroids during the MAP trial.
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Nova |
2017 |
Barker D, D'Este C, Campbell MJ, McElduff P, 'Minimum number of clusters and comparison of analysis methods for cross sectional stepped wedge cluster randomised trials with binary outcomes: A simulation study', TRIALS, 18 (2017) [C1]
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Nova |
2017 |
Dunlop AJ, Brown AL, Oldmeadow C, Harris A, Gill A, Sadler C, et al., 'Effectiveness and cost-effectiveness of unsupervised buprenorphine-naloxone for the treatment of heroin dependence in a randomized waitlist controlled trial', Drug and Alcohol Dependence, 174 181-191 (2017) [C1]
Background Access to opioid agonist treatment can be associated with extensive waiting periods with significant health and financial burdens. This study aimed to determine whether... [more]
Background Access to opioid agonist treatment can be associated with extensive waiting periods with significant health and financial burdens. This study aimed to determine whether patients with heroin dependence dispensed buprenorphine-naloxone weekly have greater reductions in heroin use and related adverse health effects 12-weeks after commencing treatment, compared to waitlist controls and to examine the cost-effectiveness of this strategy. Methods An open-label waitlist RCT was conducted in an opioid treatment clinic in Newcastle, Australia. Fifty patients with DSM-IV-TR heroin dependence (and no other substance dependence) were recruited. The intervention group (n = 25) received take-home self-administered sublingual buprenorphine-naloxone weekly (mean dose, 22.7 ± 5.7 mg) and weekly clinical review. Waitlist controls (n = 25) received no clinical intervention. The primary outcome was heroin use (self-report, urine toxicology verified) at weeks four, eight and 12. The primary cost-effectiveness outcome was incremental cost per additional heroin-free-day. Results Outcome data were available for 80% of all randomized participants. Across the 12-weeks, treatment group heroin use was on average 19.02 days less/month (95% CI -22.98, -15.06, p < 0.0001). A total 12-week reduction in adjusted costs including crime of $A5,722 (95% CI 3299, 8154) in favor of treatment was observed. Excluding crime, incremental cost per heroin-free-day gained from treatment was $A18.24 (95% CI 4.50, 28.49). Conclusion When compared to remaining on a waitlist, take-home self-administered buprenorphine-naloxone treatment is associated with significant reductions in heroin use for people with DSM-IV-TR heroin dependence. This cost-effective approach may be an efficient strategy to enhance treatment capacity.
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Nova |
2017 |
Dunn A, Marsden DL, Barker D, Van Vliet P, Spratt NJ, Callister R, 'Cardiorespiratory fitness and walking endurance improvements after 12 months of an individualised home and community-based exercise programme for people after stroke.', Brain injury, 31 1617-1624 (2017) [C1]
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Nova |
2017 |
Wiggers J, McElwaine K, Freund M, Campbell L, Bowman J, Wye P, et al., 'Increasing the provision of preventive care by community healthcare services: a stepped wedge implementation trial', IMPLEMENTATION SCIENCE, 12 (2017) [C1]
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Nova |
2017 |
Collins CE, Morgan PJ, Hutchesson MJ, Oldmeadow C, Barker D, Callister R, 'Efficacy of Web-Based Weight Loss Maintenance Programs: A Randomized Controlled Trial Comparing Standard Features Versus the Addition of Enhanced Personalized Feedback over 12 Months.', Behavioral sciences (Basel, Switzerland), 7 (2017) [C1]
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Nova |
2017 |
Reeves AJ, McEvoy MA, MacDonald-Wicks LK, Barker D, Attia J, Hodge AM, Patterson AJ, 'Calculation of Haem Iron Intake and Its Role in the Development of Iron Deficiency in Young Women from the Australian Longitudinal Study on Women's Health', NUTRIENTS, 9 (2017) [C1]
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Nova |
2016 |
Barker D, McElduff P, D'Este C, Campbell MJ, 'Stepped wedge cluster randomised trials: a review of the statistical methodology used and available', BMC MEDICAL RESEARCH METHODOLOGY, 16 (2016) [C1]
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Nova |
2016 |
Bartlem KM, Bowman J, Freund M, Wye PM, Barker D, McElwaine KM, et al., 'Effectiveness of an intervention in increasing the provision of preventive care by community mental health services: a non-randomized, multiple baseline implementation trial', IMPLEMENTATION SCIENCE, 11 (2016) [C1]
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Nova |
2016 |
Paul CL, Boyes AW, O'Brien L, Baker AL, Henskens FA, Roos I, et al., 'Protocol for a Randomized Controlled Trial of Proactive Web-Based Versus Telephone-Based Information and Support: Can Electronic Platforms Deliver Effective Care for Lung Cancer Patients?', JMIR RESEARCH PROTOCOLS, 5 (2016)
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2016 |
Paul CL, Piterman L, Shaw JE, Kirby C, Barker D, Robinson J, et al., 'Patterns of type 2 diabetes monitoring in rural towns: How does frequency of HbA1c and lipid testing compare with existing guidelines?', Australian Journal of Rural Health, 24 371-377 (2016) [C1]
Objective: To indicate levels of monitoring of type 2 diabetes in rural and regional Australia by examining patterns of glycated haemoglobin (HbA1c) and blood lipid testing. Desig... [more]
Objective: To indicate levels of monitoring of type 2 diabetes in rural and regional Australia by examining patterns of glycated haemoglobin (HbA1c) and blood lipid testing. Design and Setting: Retrospective analysis of pathology services data from twenty regional and rural towns in eastern Australia over 24 months. Participants: Of 13 105 individuals who had either a single HbA1c result =7.0% (53 mmol mol-1); or two or more HbA1c tests within the study period. Main outcome measures: Frequency of testing of HbA1c and blood lipids (cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol and triglycerides) were compared with guideline recommendations. Results: About 58.3% of patients did not have the recommended 6-monthly HbA1c tests and 30.6% did not have annual lipid testing. For those who did not receive tests at the recommended interval, the mean between-test interval was 10.5 months (95% CI = 7.5¿13.5) rather than 6 months for HbA1c testing; and 15.7 (95% CI = 13.3¿18.1) months rather than annually for blood lipids. For those with at least one out-of-range test result, 77% of patients failed to receive a follow-up HbA1c test and 86.5% failed to receive a follow-up blood lipid test within the recommended 3 months. Patients less than 50 years of age, living in a more remote area and with poor diabetes control were less likely to have testing at the recommended intervals (P < 0.0001). Conclusions: Although poor diabetes testing is not limited to rural areas, more intensive diabetes monitoring is likely to be needed for patients living in non-metropolitan areas, particularly for some subgroups.
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Nova |
2015 |
Magin P, Dunbabin J, Goode S, Valderas JM, Levi C, D'Souza M, et al., 'Patients' responses to transient ischaemic attack symptoms: A cross-sectional questionnaire study in Australian general practices', British Journal of General Practice, 65 e24-e31 (2015) [C1]
Background Consensus guidelines for transient ischaemic attack (TIA) recommend urgent investigation and management, but delays in management occur and are attributable to patient ... [more]
Background Consensus guidelines for transient ischaemic attack (TIA) recommend urgent investigation and management, but delays in management occur and are attributable to patient and health system factors. Aim To establish general practice patients' anticipated responses to TIA symptoms, and associations of appropriate responses. Design and setting A cross-sectional questionnaire-based study in Australian general practices. Method Consecutive patients attending general practices completed questionnaires that contained the Stroke Action Test (STAT) adapted for TIA about demographic, health system use, and stroke risk factors. STAT elicits appropriate or inappropriate anticipated responses to 28 symptom complexes. Anticipated actions in-hours and out-of-hours were elicited. Associations of independent variables with adapted-STAT scores were tested with multiple linear regression. Results There were 854 participants (response rate 76.9%). Urgent healthcare-seeking responses to transient neurological symptoms ranged from 96.8% for right-sided weakness with dysphasia to 59.1% for sudden dizziness. Associations of higher adapted-STAT scores were older age, Indigenous status, previous after-hours services use, self-perception of health as poor, and familiarity with a stroke public awareness campaign. A personal or family history of stroke, smoking status, and time of event (in-hours/out-of-hours) were not significantly associated with adapted-STAT scores. Conclusion Most general practice attendees expressed intentions to seek health care urgently for most symptoms suggestive of TIA, with highest levels of urgency observed in high stroke-risk scenarios. Intentions were not associated with a number of major risk factors for TIA and might be improved by further educational interventions, either targeted or at population level.
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Nova |
2015 |
Kodur S, Ahmad W, Heittarachi M, Reeves G, Attia J, Barker D, Collins N, 'Influence of age on outcome in patients with pulmonary arterial hypertension', Heart Lung and Circulation, 24 719-723 (2015) [C1]
Background: The development of effective orally administered medical therapy for pulmonary arterial hypertension (PAH) has made a significant impact on outcome in patients with PA... [more]
Background: The development of effective orally administered medical therapy for pulmonary arterial hypertension (PAH) has made a significant impact on outcome in patients with PAH. Identification of patient groups likely to derive optimal benefit is important, given cost and potential side effects; the clinical effectiveness of these therapies in older patients with PAH is unclear as the presence of co-morbidity may limit benefits of therapy. Aims: We evaluated the epidemiology of PAH in a contemporary cohort to assess the influence of age on long-term outcome using PAH-specific therapies. Results: A total of 119 patients (88% female; mean age 65±12 years) were reviewed, comprising 52% with underlying connective tissue disease. Bosentan was the PAH specific agent most frequently used. The baseline 6MWT distance in the entire cohort was 304m with age associated with a significant decline in 6MWT. Conclusions: In a large cohort of patients treated with PAH-specific therapies, patients less than 55 years of age showed improvement in 6MWT with older patients demonstrating stabilisation or decline.
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Nova |
2014 |
Campbell HS, Hall AE, Sanson-Fisher RW, Barker D, Turner D, Taylor-Brown J, 'Development and validation of the Short-Form Survivor Unmet Needs Survey (SF-SUNS)', Supportive Care in Cancer, 22 1071-1079 (2014) [C1]
Purpose: The Survivor Unmet Needs Survey (SUNS) is one of the only unmet needs measures that was developed and evaluated utilising a population-based sample of cancer survivors. A... [more]
Purpose: The Survivor Unmet Needs Survey (SUNS) is one of the only unmet needs measures that was developed and evaluated utilising a population-based sample of cancer survivors. At 89 items, the current scale is quite burdensome. The current study aimed to develop a valid and reliable short version of this survey. Methods: A heterogeneous sample of 1,589 cancer survivors, aged 19 years or over at diagnosis, diagnosed with a histologically confirmed cancer in the previous 12 to 60 months, completed the SUNS. Using these data, we employed a combined theoretical and statistical method of reducing the number of items in the SUNS. The shortened survey was examined for construct validity, internal consistency, discriminant validity and floor and ceiling effects. Results: Fifty-nine items were removed. Construct validity closely reflected the original structure of the SUNS. However, all items from the Emotional health and Relationships domains loaded onto one factor. Cronbach's alpha for the final four domains were 0.85 or above, demonstrating strong internal consistency. Intra-class correlations of the three domains from the original survey (Financial concerns, Information and Access and continuity of care) and shortened survey were high (>0.9). Discriminant validity illustrated the short-form SUNS' ability to discriminate between those who had recently received treatment and those who had not. Conclusions: This study describes the development and psychometric evaluation of the short-form SUNS (SF-SUNS). Future studies should confirm the test-retest reliability and predictive validity of the SF-SUNS utilising large, independent, population-based samples of cancer survivors. © 2013 Springer-Verlag.
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Nova |
2014 |
Campbell SH, Carey M, Sanson-Fisher R, Barker D, Turner D, Taylor-Brown J, Hall A, 'Measuring the unmet supportive care needs of cancer support persons: The development of the Support Person's Unmet Needs Survey - short form', European Journal of Cancer Care, 23 255-262 (2014) [C1]
Few rigorous measures of unmet needs have been developed for cancer support persons. This study describes the development of a short version of the Support Person's Unmet Nee... [more]
Few rigorous measures of unmet needs have been developed for cancer support persons. This study describes the development of a short version of the Support Person's Unmet Needs Survey (SPUNS). Cancer survivors [n = 1589, 612 (52%) men, mean age of 62.5 years, SD 11.5] 1-5 years post diagnosis and recruited through three Canadian population-based cancer registries were asked to pass a survey package on to their principal support person. Surveys were returned by 1183 support persons. The survey included the long form of the SPUNS, which contains 78 items. Fifty-two items were deleted using a combination of expert opinion and statistical criteria. Analysis of the remaining items revealed a five-factor structure. The original factors were retained with the exception of a merging of the personal and emotional needs subscales. Cronbach's alpha co-efficients for all subscales were =0.87, and intraclass correlation of domain scores of the short and long versions of the SPUNS were high. The SPUNS short form was able to discriminate between support persons of survivors who had (n = 147), and those who had not received treatment in the past month (n = 969). At just 26 items, it is likely to have strong clinical and research applicability. © 2013 John Wiley & Sons Ltd.
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Nova |
2014 |
Williamson A, Redman S, Haynes A, Barker D, Jorm L, Green S, et al., 'Supporting Policy In health with Research: an Intervention Trial (SPIRIT) protocol for a stepped wedge trial', BMJ Open, 4 (2014)
Introduction: Governments in different countries have committed to better use of evidence from research in policy. Although many programmes are directed at assisting agencies to b... [more]
Introduction: Governments in different countries have committed to better use of evidence from research in policy. Although many programmes are directed at assisting agencies to better use research, there have been few tests of the effectiveness of such programmes. This paper describes the protocol for SPIRIT (Supporting Policy In health with Research: an Intervention Trial), a trial designed to test the effectiveness of a multifaceted programme to build organisational capacity for the use of research evidence in policy and programme development. The primary aim is to determine whether SPIRIT results in an increase in the extent to which research and research expertise is sought, appraised, generated and used in the development of specific policy products produced by health policy agencies. Methods and analysis: A stepped wedge cluster randomised trial involving six health policy agencies located in Sydney, Australia. Policy agencies are the unit of randomisation and intervention. Agencies were randomly allocated to one of three start dates (steps) to receive the 1-year intervention programme, underpinned by an action framework. The SPIRIT intervention is tailored to suit the interests and needs of each agency and includes audit, feedback and goal setting; a leadership programme; staff training; the opportunity to test systems to assist in the use of research in policies; and exchange with researchers. Outcome measures will be collected at each agency every 6 months for 30 months (starting at the beginning of step 1). Ethics and dissemination: Ethics approval was granted by the University of Western Sydney Human Research and Ethics Committee HREC Approval H8855. The findings of this study will be disseminated broadly through peer-reviewed publications and presentations at conferences and used to inform future strategies.
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2013 |
Handley TE, Attia JR, Inder KJ, Kay-Lambkin FJ, Barker D, Lewin TJ, Kelly BJ, 'Longitudinal course and predictors of suicidal ideation in a rural community sample.', Australian & New Zealand Journal of Psychiatry, 47 1032-1040 (2013) [C1]
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Nova |
2013 |
Lambert SD, Girgis A, McElduff P, Turner J, Levesque JV, Kayser K, et al., 'A parallel-group, randomised controlled trial of a multimedia, self-directed, coping skills training intervention for patients with cancer and their partners: Design and rationale', BMJ Open, 3 (2013) [C2]
Introduction: Coping skills training interventions have been found to be efficacious in helping both patients and their partners manage the physical and emotional challenges they ... [more]
Introduction: Coping skills training interventions have been found to be efficacious in helping both patients and their partners manage the physical and emotional challenges they face following a cancer diagnosis. However, many of these interventions are costly and not sustainable. To overcome these issues, a self-directed format is increasingly used. The efficacy of self-directed interventions for patients has been supported; however, no study has reported on the outcomes for their partners. This study will test the efficacy of Coping-Together - a multimedia, self-directed, coping skills training intervention for patients with cancer and their partners. Methods and analysis: The proposed three-group, parallel, randomised controlled trial will recruit patients diagnosed in the past 4 months with breast, prostate, colorectal cancer or melanoma through their treating clinician. Patients and their partners will be randomised to (1) a minimal ethical care (MEC) condition - selected Cancer Council New South Wales booklets and a brochure for the Cancer Council Helpline, (2) Coping-Together generic - MEC materials, the six Coping-Together booklets and DVD, the Cancer Council Queensland relaxation audio CD and login to the Coping-Together website or (3) Coping-Together tailored - MEC materials, the Coping-Together DVD, the login to the website and only those Coping-Together booklet sections that pertain to their direct concerns. Anxiety (primary outcome), distress, depression, dyadic adjustment, quality of life, illness or caregiving appraisal, self-efficacy and dyadic and individual coping will be assessed before receiving the study material (ie, baseline) and again at 3, 6 and 12 months postbaseline. Intention-to-treat and per protocol analysis will be conducted. Ethics and dissemination: This study has been approved by the relevant local area health and University ethics committees. Study findings will be disseminated not only through peer-reviewed publications and conference presentations but also through educational outreach visits, publication of lay research summaries in consumer newsletters and publications targeting clinicians.
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Nova |
2013 |
Talseth-Palmer BA, Wijnen JT, Barker D, Vasen HFA, Scott RJ, 'Is the reported modifying effect of 8q23.3 and 11q23.1 on colorectal cancer risk for MLH1 mutation carriers valid? Reply', INTERNATIONAL JOURNAL OF CANCER, 133 1764-1764 (2013) [C3]
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2013 |
Talseth-Palmer B, Wijnen JT, Brenne IS, Jagmohan-Changur S, Barker DJ, Ashton KA, et al., 'Combined analysis of three Lynch syndrome cohorts confirms the modifying effects of 8q23.3 and 11q23.1 in MLH1 mutation carriers', International Journal of Cancer, 132 1487-1729 (2013) [C1]
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Nova |
2013 |
Bonevski B, O'Brien J, Frost S, Yiow L, Oakes W, Barker D, 'Novel setting for addressing tobacco-related disparities: a survey of community welfare organization smoking policies, practices and attitudes', HEALTH EDUCATION RESEARCH, 28 46-57 (2013) [C1]
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Nova |
2013 |
Carey M, Bryant J, Yoong SL, Russell G, Barker D, Sanson-Fisher R, 'Prostate specific antigen testing in family practice: a cross sectional survey of self-reported rates of and reasons for testing participation and risk disclosure', BMC FAMILY PRACTICE, 14 (2013) [C1]
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Nova |
2013 |
Courtney RJ, Paul CL, Carey ML, Sanson-Fisher RW, Macrae FA, D'Este C, et al., 'A population-based cross-sectional study of colorectal cancer screening practices of first-degree relatives of colorectal cancer patients', BMC CANCER, 13 (2013) [C1]
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Nova |
2013 |
Nathan N, Wolfenden L, Morgan PJ, Bell AC, Barker D, Wiggers J, 'Validity of a self-report survey tool measuring the nutrition and physical activity environment of primary schools', INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY, 10 (2013) [C1]
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Nova |
2013 |
Talseth-Palmer BA, Wijnen JT, Andreassen EK, Barker D, Jagmohan-Changur S, Tops CM, et al., 'The importance of a large sample cohort for studies on modifier genes influencing disease severity in FAP patients.', Hered Cancer Clin Pract, 11 20 (2013) [C1]
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Nova |
2012 |
Wood LG, Garg ML, Smart JM, Scott HA, Barker D, Gibson PG, 'Manipulating antioxidant intake in asthma: A randomized controlled trial', American Journal of Clinical Nutrition, 96 534-543 (2012) [C1]
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Nova |
2011 |
Paul CL, Sanson-Fisher RW, Douglas HE, Clinton-Mcharg TL, Williamson A, Barker DJ, 'Cutting the research pie: A value-weighting approach to explore perceptions about psychosocial research priorities for adults with haematological cancers', European Journal of Cancer Care, 20 345-353 (2011) [C1]
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Nova |
2011 |
Kypri K, Jones C, McElduff P, Barker DJ, 'Effects of restricting pub closing times on night-time assaults in an Australian city', Addiction, 106 303-310 (2011) [C1]
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Nova |
2010 |
Marsden DL, Spratt NJ, Walker R, Barker DJ, Attia JR, Pollack MR, et al., 'Trends in stroke attack rates and case fatality in the Hunter Region, Australia 1996-2008', Cerebrovascular Diseases, 30 500-507 (2010) [C1]
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Nova |
2010 |
Gwynn JD, Hardy LL, Wiggers JH, Smith WT, D'Este CA, Turner N, et al., 'The validation of a self-report measure and physical activity of Australian Aboriginal and Torres Strait Islander and non-Indigenous rural children', Australian and New Zealand Journal of Public Health, 34 S57-S65 (2010) [C1]
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Nova |
2009 |
MacDonald K, Lowe J, Barker DJ, Mensch M, Attia JR, 'Effect of popular takeaway foods on blood glucose levels in type 1 diabetes mellitus patients on intensive insulin therapy', International Journal of Clinical Practice, 63 189-194 (2009) [C1]
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Nova |