Associate Professor Mark McEvoy

Associate Professor Mark McEvoy

Associate Professor

School of Medicine and Public Health (Public Health)

Career Summary

Biography

Dr Mark McEvoy is an Epidemiologist/Senior Lecturer with an active research program in the molecular and genetic epidemiology of chronic disease. Previously he was the recipient of the Vincent Fairfax Foundation Research Fellowship in Epidemiology where he worked as the principal Research Fellow on the Hunter Community (Cohort) Study, the Hunter’s largest and most comprehensive population-based prospective longitudinal study of ageing and chronic disease.

High quality research and innovation

As an Epidemiologist with a primary interest in chronic disease he has successfully developed five key areas of research aimed at identifying new risk factors and developing prevention strategies for chronic diseases that fall within the National Health Priority areas. To achieve this he has established cross-disciplinary collaborations with national and international researchers in genetics, nutrition, mental health, cardiovascular medicine, and gastroenterology. This has resulted in collaborations across Australia, Asia, USA, and Europe and culminated in a total of 120 publications; over half of these are in moderate or high impact journals including Nature Genetics and JAMA. The impact of this research has been significant having received over 2200 citations and an H-index of 26 (Google Scholar). Overall since commencing at the University of Newcastle he has attracted over $3.2 million in research funds.

He has a particular interest in methylarginine and nitric oxide/nitrate in relation to chronic disease and has produced ‘world-first’ publications in this field. His interest in Gastroenterology and the gut microbiome has led to a number of research projects currently examining the role of the gut microbiota in neurological disease. He recently published an article in Gastroenterology demonstrating an association between Irritable Bowel Syndrome (a marker of gut dysbiosis) and the eye disease - glaucoma. This is the very first report in the scientific literature of a disease link between the gut and the eye and this has facilitated collaboration between the University of Newcastle, Karolinska Institute, Sweden, Aarhus University, Denmark, Flinders University, and UNSW to investigate the biological basis of this association further.

Dr McEvoy is currently supervising 10 research higher degree students (7 PhD, 1 MPhil., 2 Honours). Since his appointment to Senior lecturer at the end of 2013 he has supervised 7 RHD students to completion (2 PhD, 5 Honours). Five of the seven PhD projects and 1 honours project were conceptualised by Dr McEvoy. He developed the ideas and recruited the appropriate students to conduct the research and the co-supervisors to help supervise the projects.

Research collaboration and partnerships

As a chronic disease epidemiologist cross-disciplinary collaborations are essential to identifying new modifiable risk factors and prevention strategies for chronic disease. As a result, Dr McEvoy has actively pursued research leaders in the disciplines of genetics, nutrition, mental health, cardiovascular medicine, and gastroenterology and established collaborations across Australia, Asia, USA, and Europe to facilitate this research. These initiatives have resulted in 16 international research partnerships with institutions such as Oxford University, Cambridge University, Imperial College London, Harvard Medical School, and Karolinska Institute. These collaborations have made significant achievements in identifying new genetic variants associated with Stroke, Irritable Bowel Syndrome, Chronic kidney disease, bone mineral density, endometrial cancer, and graft rejection in liver transplantation and have been published in high impact journals including American Journal of Gastroenterology and Stroke. In the area of nutrition he has made important contributions to understanding the role of fatty acids, dietary patterns, and dietary zinc to conditions such as type 2 diabetes and depression. This includes a highly cited publication in the American Journal of Clinical Nutrition - the field’s top journal. Each year he receives invitations from international research groups to contribute to the development of systematic reviews. For example, an ongoing collaboration with Mahidol University, Thailand has resulted in two systematic reviews since 2014 and 15 overall published in journals like American Journal of Epidemiology since 2007.

Research – Future Directions

As a chronic disease Epidemiologist Dr McEvoy has successfully developed research aimed at identifying new risk factors and developing prevention strategies for chronic diseases. Over the next 2-3 years he will continue to focus on identifying risk factors and developing prevention strategies for chronic disease. To achieve this he will continue to develop international cross-disciplinary collaborations. Research projects currently underway or being developed include:

  1. Investigating the role dietary nitric oxide donors (nitrate, nitrite) for disease prevention (CVD, GI disorders).
  2. An examination of the association of early life exposures (e.g. antibiotics, caesarean section, infection) that modify the gastrointestinal microbiota with mental health outcomes in young adults using data from the Avon Longitudinal Study of Parents & Children; a collaboration with Bristol university in the UK.
  3. Animal and human research to validate and characterise the epidemiological association between IBS (gut dysbiosis) and glaucoma.
  4. Animal and human research to examine the role of the gut microbiota in neuroprotection after stroke and in Cardio-protection after ischaemia/myocardial infarction.

Qualifications

  • Doctor of Philosophy, University of Newcastle
  • Bachelor of Science, University of Newcastle
  • Graduate Diploma in Genetic Counselling, University of Newcastle
  • Master of Medical Science (Clinical Epidemiology), University of Newcastle

Keywords

  • Cardiovascular disease
  • Chronic disease
  • Epidemiology
  • Gastrointestinal disorders
  • Genetic Epidemiology
  • Methylarginines
  • Microbiome
  • Molecular Epidemiology
  • Public health

Fields of Research

Code Description Percentage
110399 Clinical Sciences not elsewhere classified 30
111799 Public Health and Health Services not elsewhere classified 60
130299 Curriculum and Pedagogy not elsewhere classified 10

Professional Experience

UON Appointment

Title Organisation / Department
Associate Professor University of Newcastle
School of Medicine and Public Health
Australia

Academic appointment

Dates Title Organisation / Department
1/01/2007 -  Lecturer University of Newcastle
School of Medicine and Public Health
Australia
1/01/2004 - 1/12/2006 Research fellow University of Newcastle
School of Medicine and Public Health-Epidemiology
Australia
1/08/2001 - 1/12/2003 Research officer University of Newcastle
Newcastle Institute of Public Health
Australia
Edit

Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Journal article (110 outputs)

Year Citation Altmetrics Link
2016 Islam MR, Attia J, Ali L, McEvoy M, Selim S, Sibbritt D, et al., 'Zinc supplementation for improving glucose handling in pre-diabetes: A double blind randomized placebo controlled pilot study', Diabetes Research and Clinical Practice, 115 39-46 (2016)

© 2016 Elsevier Ireland Ltd.Aims: There are a number of studies showing that zinc supplementation may improve glucose handling in people with established diabetes. We sought to i... [more]

© 2016 Elsevier Ireland Ltd.Aims: There are a number of studies showing that zinc supplementation may improve glucose handling in people with established diabetes. We sought to investigate whether this zinc-dependent improvement in glucose handling could potentially be harnessed to prevent the progression of pre-diabetes to diabetes. In this double-blind randomized placebo-controlled trial, we determined participants' fasting blood glucose levels, (FBG) and Homeostasis Model Assessment (HOMA) parameters (beta cell function, insulin sensitivity and insulin resistance) at baseline and after 6 months of zinc supplementation. Methods: The Bangladesh Institute of Health Sciences Hospital (BIHS) (Mirpur, Dhaka, Bangladesh) database was used to identify 224 patients with prediabetes, of whom 55 met the inclusion criteria and agreed to participate. The participants were randomized either to the intervention or control group using block randomization. The groups received either 30 mg zinc sulphate dispersible tablet or placebo, once daily for six months. Results: After six months, the intervention group significantly improved their FBG concentration compared to the placebo group (5.37 ± 0.20 mmol/L vs 5.69 ± 0.26, p < 0.001) as well as compared to their own baseline (5.37 ± 0.20 mmol/L vs 5.8 ± 0.09, p < 0.001). Beta cell function, insulin sensitivity and insulin resistance all showed a statistically significant improvement as well. Conclusion: To our knowledge this is the first trial to show an improvement in glucose handling using HOMA parameters in participants with prediabetes. Larger randomized controlled trials are warranted to confirm these findings and to explore clinical endpoints.

DOI 10.1016/j.diabres.2016.03.010
Co-authors Roseanne Peel, Milton Hasnat, John Attia
2016 Gunathilake R, Oldmeadow C, McEvoy M, Inder KJ, Schofield PW, Nair BR, Attia J, 'The Association Between Obesity and Cognitive Function in Older Persons: How Much Is Mediated by Inflammation, Fasting Plasma Glucose, and Hypertriglyceridemia?', J Gerontol A Biol Sci Med Sci, (2016)
DOI 10.1093/gerona/glw070
Co-authors Kerry Inder, Peter Schofield, Christopher Oldmeadow, John Attia
2016 Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, et al., 'Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.', Nat Commun, 7 10023 (2016)
DOI 10.1038/ncomms10023
Co-authors Rodney Scott, Liz Holliday, John Attia
2016 Ren S, Hure A, Peel R, D'Este C, Abhayaratna W, Tonkin A, et al., 'Rationale and design of a randomized controlled trial of pneumococcal polysaccharide vaccine for prevention of cardiovascular events: The Australian Study for the Prevention through Immunization of Cardiovascular Events (AUSPICE)', American Heart Journal, 177 58-65 (2016)

© 2016 Elsevier, Inc.Background Research has shown that vaccination with Streptococcus pneumoniae reduced the extent of atherosclerosis in experimental animal models. It is thoug... [more]

© 2016 Elsevier, Inc.Background Research has shown that vaccination with Streptococcus pneumoniae reduced the extent of atherosclerosis in experimental animal models. It is thought that phosphorylcholine lipid antigens in the S. pneumoniae cell wall induce the production of antibodies that cross-react with oxidized low-density lipoprotein, a component of atherosclerotic plaques. These antibodies may bind to and facilitate the regression of the plaques. Available data provide evidence that similar mechanisms also occur in humans, leading to the possibility that pneumococcal vaccination protects against atherosclerosis. A systematic review and meta-analysis, including 8 observational human studies, of adult pneumococcal polysaccharide vaccination for preventing cardiovascular disease in people older than 65 years, showed a 17% reduction in the odds (odds ratio 0.83, 95% CI 0.71-0.97) of having an acute coronary syndrome event. Methods/Design The AUSPICE is a multicenter, randomized, placebo-controlled, double-blind, clinical trial to formally test whether vaccination with the pneumococcal polysaccharide vaccine protects against cardiovascular events (fatal and nonfatal acute coronary syndromes and ischemic strokes). Cardiovascular outcomes will be obtained during 4 to 5 years of follow-up, through health record linkage with state and national administrative data sets. Conclusion This is the first registered randomized controlled trial (on US, World Health Organization, Australia and New Zealand trial registries) to be conducted to test whether vaccination with the pneumococcal polysaccharide vaccine will reduce cardiovascular events. If successful, vaccination can be readily extended to at-risk groups to reduce the risk of cardiovascular diseases.

DOI 10.1016/j.ahj.2016.04.003
Co-authors Philip Hansbro, Chris Levi, Alexis Hure, John Attia, David Durrheim
2016 Mather KA, Thalamuthu A, Oldmeadow C, Song F, Armstrong NJ, Poljak A, et al., 'Genome-wide significant results identified for plasma apolipoprotein H levels in middle-aged and older adults.', Sci Rep, 6 23675 (2016)
DOI 10.1038/srep23675
Co-authors Liz Holliday, Rodney Scott, John Attia, Peter Schofield, Christopher Oldmeadow
2016 Lai JS, Oldmeadow C, Hure AJ, McEvoy M, Byles J, Attia J, 'Longitudinal diet quality is not associated with depressive symptoms in a cohort of middle-aged Australian women', British Journal of Nutrition, 1-9 (2016)

Copyright © The Authors 2016 There is increasing evidence for the role of nutrition in the prevention of depression. This study aims to describe changes in diet quality over 12 y... [more]

Copyright © The Authors 2016 There is increasing evidence for the role of nutrition in the prevention of depression. This study aims to describe changes in diet quality over 12 years among participants in the Australian Longitudinal Study on Women¿s Health in relation to changes in depressive symptoms. Women born between 1946 and 1951 were followed-up for 12 years (2001¿2013). Dietary intake was assessed using the Dietary Questionnaire for Epidemiological Studies (version 2) in 2001, 2007 and every 2¿3 years after that until 2013. Diet quality was summarised using the Australian Recommended Food Score (ARFS). Depressive symptoms were measured using the ten-item Centre for Epidemiologic Depression Scale at every 2¿3-year intervals during 2001¿2013. Linear mixed models were used to examine trends in diet quality and its sub-components. The same model including time-varying covariates was used to examine associations between diet quality and depressive symptoms adjusting for confounders. Sensitivity analyses were carried out using the Mediterranean dietary pattern (MDP) index to assess diet quality. Minimal changes in overall diet quality and its sub-components over 12 years were observed. There was a significant association between baseline diet quality and depression (ß=-0·24, P=0·001), but this was lost when time-varying covariates were added (ß=-0·04, P=0·10). Sensitivity analyses showed similar performance for both ARFS and MDP in predicting depressive symptoms. In conclusion, initial associations seen when using baseline measures of diet quality and depressive symptoms disappear when using methods that handle time-varying covariates, suggesting that previous studies indicating a relationship between diet and depression may have been affected by residual confounding.

DOI 10.1017/S000711451500519X
Co-authors John Attia, Alexis Hure, Julie Byles, Christopher Oldmeadow
2016 de Vries PS, Chasman DI, Sabater-Lleal M, Chen MH, Huffman JE, Steri M, et al., 'A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.', Hum Mol Genet, 25 358-370 (2016)
DOI 10.1093/hmg/ddv454
Co-authors John Attia, Rodney Scott, Christopher Oldmeadow, Liz Holliday
2016 Cheng TH, Thompson DJ, O'Mara TA, Painter JN, Glubb DM, Flach S, et al., 'Five endometrial cancer risk loci identified through genome-wide association analysis.', Nat Genet, 48 667-674 (2016)
DOI 10.1038/ng.3562
Citations Scopus - 1
Co-authors Liz Holliday, John Attia
2016 Chen MM, O'Mara TA, Thompson DJ, Painter JN, Australian National Endometrial Cancer Study Group (ANECS), Attia J, et al., 'GWAS meta-analysis of 16 852 women identifies new susceptibility locus for endometrial cancer.', Hum Mol Genet, (2016)
DOI 10.1093/hmg/ddw092
Co-authors John Attia, Liz Holliday
2016 Jackson J, Williams R, McEvoy M, MacDonald-Wicks L, Patterson A, 'Is higher consumption of animal flesh foods associated with better iron status among adults in developed countries? A systematic review', Nutrients, 8 (2016)

© 2016 by the authors; licensee MDPI, Basel, Switzerland.Iron deficiency (ID) is the most prevalent nutrient deficiency within the developed world. This is of concern as ID has b... [more]

© 2016 by the authors; licensee MDPI, Basel, Switzerland.Iron deficiency (ID) is the most prevalent nutrient deficiency within the developed world. This is of concern as ID has been shown to affect immunity, thermoregulation, work performance and cognition. Animal flesh foods provide the richest and most bioavailable source of dietary (haem) iron, however, it is unclear whether low animal flesh diets contribute to ID. This systematic review aimed to investigate whether a higher consumption of animal flesh foods is associated with better iron status in adults. CINAHL, Cochrane, EMBASE and MEDLINE were searched for published studies that included adults (¥18 years) from developed countries and measured flesh intakes in relation to iron status indices. Eight experimental and 41 observational studies met the inclusion criteria. Generally, studies varied in population and study designs and results were conflicting. Of the seven high quality studies, five showed a positive association between animal flesh intake (85¿300 g/day) and iron status. However, the optimum quantity or frequency of flesh intake required to maintain or achieve a healthy iron status remains unclear. Results show a promising relationship between animal flesh intake and iron status, however, additional longitudinal and experimental studies are required to confirm this relationship and determine optimal intakes to reduce ID development.

DOI 10.3390/nu8020089
Co-authors Amanda Patterson, Lesley Wicks
2016 Thompson DJ, O'Mara TA, Glubb DM, Painter JN, Cheng T, Folkerd E, et al., 'CYP19A1 fine-mapping and Mendelian randomization: Estradiol is causal for endometrial cancer', Endocrine-Related Cancer, 23 77-91 (2016)

© 2016 The authors.Candidate gene studies have reported CYP19A1 variants to be associated with endometrial cancerandwith estradiol (E2) concentrations.We analyzed2937singlenucleo... [more]

© 2016 The authors.Candidate gene studies have reported CYP19A1 variants to be associated with endometrial cancerandwith estradiol (E2) concentrations.We analyzed2937singlenucleotidepolymorphisms (SNPs) in 6608 endometrial cancer cases and 37 925 controls and report the first genome widesignificant association between endometrial cancer and a CYP19A1 SNP (rs727479 in intron 2, P=4.8×10-11). SNP rs727479 was also among those most strongly associated with circulating E2 concentrations in 2767 post-menopausal controls (P=7.4×10-8). The observed endometrial cancer odds ratio per rs727479 A-allele (1.15, CI=1.11-1.21) is compatible with that predicted by theobservedeffectonE2 concentrations (1.09, CI=1.03-1.21), consistentwith the hypothesis that endometrial cancer risk is driven by E2. From 28 candidate-causal SNPs, 12 co-located with three putative gene-regulatory elements and their risk alleles associated with higher CYP19A1 expression in bioinformatical analyses. For both phenotypes, the associationswith rs727479 were stronger amongwomen with a higher BMI (PinteractionZ0.034 and 0.066 respectively), suggesting a biologically plausible gene-environment interaction.

DOI 10.1530/ERC-15-0386
Citations Scopus - 2
Co-authors Katie Ashton, Rodney Scott, Liz Holliday, John Attia
2016 Lai JS, Oldmeadow C, Hure AJ, McEvoy M, Hiles SA, Boyle M, Attia J, 'Inflammation mediates the association between fatty acid intake and depression in older men and women', Nutrition Research, 36 234-245 (2016)

© 2016 Elsevier Inc.Antioxidants and fatty acids are associated with depression and inflammation, and inflammation appears to predict depression risk; hence, the associations bet... [more]

© 2016 Elsevier Inc.Antioxidants and fatty acids are associated with depression and inflammation, and inflammation appears to predict depression risk; hence, the associations between these nutrients and depression may be mediated by inflammation. We hypothesized that inflammatory markers interleukin (IL)-6 and C-reactive protein (CRP) mediate the associations between antioxidant and fatty acid intakes, and depression. Participants were from the Hunter Community Study, a longitudinal cohort of adults aged 55-85 years. Dietary intake was assessed using the Older Australian's Food Frequency Questionnaire. Fasting blood samples were drawn for analysis of nutrient and inflammatory biomarkers. Depressive symptoms were assessed using the 20-item Center for Epidemiologic Studies-Depression scale at baseline and at 5-year follow-up. Linear mixed models were used to investigate longitudinal associations between dietary intakes and depression, and mediation analyses were carried out to determine if IL-6 and/or CRP were the mediators. Analyses were conducted on men and women separately and adjusted for potential confounders. Fruit and monounsaturated fat intakes were negatively associated with depression, whereas total fat and saturated fat intakes were positively associated with depression in both sexes. Omega-3 polyunsaturated fat was inversely associated with depression in men only. IL-6 was a significant mediator of the association between fruits with low carotenoid content and depression in women. CRP significantly mediated the relationship between total fat, saturated fat, and monounsaturated fat intakes and depression in women, and saturated fat intake and depression in men. Our findings raise the possibility that the association between fatty acid intake and depression is partially mediated by inflammatory markers.

DOI 10.1016/j.nutres.2015.11.017
Co-authors Christopher Oldmeadow, John Attia, Alexis Hure
2015 Cheng TH, Thompson D, Painter J, O'Mara T, Gorman M, Martin L, et al., 'Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.', Sci Rep, 5 17369 (2015) [C1]
DOI 10.1038/srep17369
Citations Scopus - 1
Co-authors Rodney Scott, Katie Ashton, Liz Holliday, John Attia
2015 Chan JPL, Thalamuthu A, Oldmeadow C, Armstrong NJ, Holliday EG, McEvoy M, et al., 'Genetics of hand grip strength in mid to late life', Age, 37 1-10 (2015) [C1]

© 2015, American Aging Association.Hand grip strength (GS) is a predictor of mortality in older adults and is moderately to highly heritable, but no genetic variants have been co... [more]

© 2015, American Aging Association.Hand grip strength (GS) is a predictor of mortality in older adults and is moderately to highly heritable, but no genetic variants have been consistently identified. We aimed to identify single nucleotide polymorphisms (SNPs) associated with GS in middle-aged to older adults using a genome-wide association study (GWAS). GS was measured using handheld dynamometry in community-dwelling men and women aged 55¿85 from the Hunter Community Study (HCS, N = 2088) and the Sydney Memory and Ageing Study (Sydney MAS, N = 541). Genotyping was undertaken using Affymetrix microarrays with imputation to HapMap2. Analyses were performed using linear regression. No genome-wide significant results were observed in HCS nor were any of the top signals replicated in Sydney MAS. Gene-based analyses in HCS identified two significant genes (ZNF295, C2CD2), but these results were not replicated in Sydney MAS. One out of eight SNPs previously associated with GS, rs550942, located near the CNTF gene, was significantly associated with GS (p = 0.005) in the HCS cohort only. Study differences may explain the lack of consistent results between the studies, including the smaller sample size of the Sydney MAS cohort. Our modest sample size also had limited power to identify variants of small effect. Our results suggest that similar to various other complex traits, many genetic variants of small effect size may influence GS. Future GWAS using larger samples and consistent measures may prove more fruitful at identifying genetic contributors for GS in middle-aged to older adults.

DOI 10.1007/s11357-015-9745-5
Co-authors Rodney Scott, John Attia, Liz Holliday, Christopher Oldmeadow, Roseanne Peel
2015 Lai JS, Hure AJ, Oldmeadow C, McEvoy M, Byles J, Attia J, 'Prospective study on the association between diet quality and depression in mid-aged women over 9 years', European Journal of Nutrition, (2015)

© 2015 Springer-Verlag Berlin HeidelbergPurpose: To examine the longitudinal association between diet quality and depression using prospective data from the Australian Longitudin... [more]

© 2015 Springer-Verlag Berlin HeidelbergPurpose: To examine the longitudinal association between diet quality and depression using prospective data from the Australian Longitudinal Study on Women¿s Health. Methods: Women born in 1946¿1951 (n = 7877) were followed over 9 years starting from 2001. Dietary intake was assessed using the Dietary Questionnaire for Epidemiological Studies (version 2) in 2001 and a shortened form in 2007 and 2010. Diet quality was summarised using the Australian Recommended Food Score. Depression was measured using the 10-item Centre for Epidemiologic Depression Scale and self-reported physician diagnosis. Pooled logistic regression models including time-varying covariates were used to examine associations between diet quality tertiles and depression. Women were also categorised based on changes in diet quality during 2001¿2007. Analyses were adjusted for potential confounders. Results: The highest tertile of diet quality was associated marginally with lower odds of depression (OR 0.94; 95 % CI 0.83, 1.00; P = 0.049) although no significant linear trend was observed across tertiles (OR 1.00; 95 % CI 0.94, 1.10; P = 0.48). Women who maintained a moderate or high score over 6 years had a 6¿14 % reduced odds of depression compared with women who maintained a low score (moderate vs low score¿OR 0.94; 95 % CI 0.80, 0.99; P = 0.045; high vs low score¿OR 0.86; 95 % CI 0.77, 0.96; P = 0.01). Similar results were observed in analyses excluding women with prior history of depression. Conclusion: Long-term maintenance of good diet quality may be associated with reduced odds of depression. Randomised controlled trials are needed to eliminate the possibility of residual confounding.

DOI 10.1007/s00394-015-1078-8
Citations Scopus - 1
Co-authors Alexis Hure, Julie Byles, Christopher Oldmeadow, John Attia
2015 Kongtharvonskul J, Anothaisintawee T, McEvoy M, Attia J, Woratanarat P, Thakkinstian A, 'Efficacy and safety of glucosamine, diacerein, and NSAIDs in osteoarthritis knee: a systematic review and network meta-analysis.', European journal of medical research, 20 24 (2015)
2015 Sharpley C, Hussain R, Wark S, Mcevoy M, Attia J, 'THE INFLUENCE OF SOCIAL SUPPORT ON PSYCHOLOGICAL DISTRESS IN OLDER PERSONS: AN EXAMINATION OF INTERACTION PROCESSES IN AUSTRALIA.', Psychol Rep, 117 883-896 (2015) [C1]
DOI 10.2466/21.10.PR0.117c27z5
Co-authors John Attia
2015 Sapkota Y, Attia J, Gordon SD, Henders AK, Holliday EG, Rahmioglu N, et al., 'Genetic burden associated with varying degrees of disease severity in endometriosis', MOLECULAR HUMAN REPRODUCTION, 21 594-602 (2015) [C1]
DOI 10.1093/molehr/gav021
Citations Scopus - 3Web of Science - 1
Co-authors Liz Holliday, John Attia, Rodney Scott
2015 Hiles SA, Baker AL, de Malmanche T, McEvoy M, Boyle M, Attia J, 'Unhealthy lifestyle may increase later depression via inflammation in older women but not men', Journal of Psychiatric Research, 63 65-74 (2015) [C1]

© 2015 Elsevier Ltd.Depression and inflammatory markers have a reliable cross-sectional association although less is known about the prospective relationship. The current study i... [more]

© 2015 Elsevier Ltd.Depression and inflammatory markers have a reliable cross-sectional association although less is known about the prospective relationship. The current study investigated whether pro-inflammatory markers are prospectively associated with depression, and whether indicators of unhealthy lifestyle, physical health and psychosocial functioning may drive this association. Participants were drawn from the Hunter Community Study, a community-dwelling cohort of individuals aged 55-85 years (N=1410). Participants completed baseline physiological assessment, health-related questionnaires, and blood sampling for the analysis of inflammatory markers, C-reactive protein (CRP) and interleukin (IL)-6. Participants completed the same depressive symptom questionnaire again after 3.5-5.5 years. Depression outcomes at follow-up were analysed dichotomously using established scale cut-off scores and continuously as a "residual score", representing the variation in follow-up depressive symptoms not explained by baseline symptoms and age. Analyses were conducted on males and females separately. At baseline, indicators of unhealthy lifestyle, physical health and psychosocial functioning were associated with depressive symptoms and inflammatory markers. For males, there were no relationships between inflammatory markers and follow-up depression outcomes. In females, IL-6 was significantly associated with depression outcomes in univariate, but not multivariate analyses. However, IL-6 significantly mediated the association between the predictors of waist-to-hip ratio, smoking and psychological coping at baseline, and follow-up depression outcomes. The results support the inflammatory hypothesis of depression, although females may be more vulnerable to effects. The findings raise the possibility that unhealthy lifestyle and psychosocial stress may drive inflammation and subsequent depressive symptoms.

DOI 10.1016/j.jpsychires.2015.02.010
Citations Scopus - 2Web of Science - 1
Co-authors Amanda Baker, John Attia
2015 Nead KT, Sharp SJ, Thompson DJ, Painter JN, Savage DB, Semple RK, et al., 'Evidence of a Causal Association Between Insulinemia and Endometrial Cancer: A Mendelian Randomization Analysis.', Journal of the National Cancer Institute, 107 (2015) [C1]
Citations Scopus - 6Web of Science - 1
Co-authors John Attia, Liz Holliday, Rodney Scott
2015 van Dyk M, Mangoni AA, McEvoy M, Attia JR, Sorich MJ, Rowland A, 'Targeted arginine metabolomics: A rapid, simple UPLC-QToF-MS

© 2015 Elsevier B.V..Background: Nitric oxide synthase (NOS) mediated conversion of arginine (ARG) to citrulline (CIT) is a key pathway for nitric oxide synthesis. ARG is also me... [more]

© 2015 Elsevier B.V..Background: Nitric oxide synthase (NOS) mediated conversion of arginine (ARG) to citrulline (CIT) is a key pathway for nitric oxide synthesis. ARG is also metabolised by alternate pathways to ornithine (ORN), homoarginine (HMA), NG-monomethyl-L-arginine (MMA), NG,. NG-dimethyl-L-arginine (ADMA) and NG,. NG'-dimethyl-L-arginine (SDMA), all of which have the capacity to alter NOS activity. Simultaneous assessment of these analytes, when assessing the impact of arginine metabolism in human disease states, is desirable. Methods: Analytes (ARG, ADMA, SDMA, MMA, HMA, CIT and ORN) were isolated from human plasma by solvent extraction, evaporated and reconstituted. Ultra-performance liquid chromatography (UPLC) was performed on a 150mm×2.1mm T3 HSS column using a gradient mobile phase comprising ammonium formate (10mM, pH3.8) in methanol (1% to 63%). Analytes were detected by time-of-flight mass spectrometry (Q-ToF-MS) in positive ion mode with electrospray ionisation (ESI+). Data were collected using MSE. Results: Solvent extraction provided high recovery (>95%). UPLC-QToF-MSE facilitated the separation and quantification of the 7 analytes in an analysis time of 6min. The approach has high sensitivity; LOQ range from 0.005µM (NMMA) to 0.25µM (ARG and ORN), and good precision; intra- and inter-day %RSD are <6% for all analytes. Conclusions: This approach provides the capacity to quantify 7 key compounds involved in ARG metabolism in a small sample volume, with a short total analysis time. These characteristics make this approach ideal for undertaking a comprehensive characterisation of this pathway in large data sets (e.g. population studies).

DOI 10.1016/j.cca.2015.05.014
Citations Scopus - 1
Co-authors John Attia
2015 Vashum KP, McEvoy MA, Hancock SJ, Islam MR, Peel R, Attia JR, Milton AH, 'Prevalence of and associations with excessive daytime sleepiness in an Australian older population', Asia-Pacific Journal of Public Health, 27 NP2275-NP2284 (2015) [C1]

© 2013 APJPH.The aim of this research is to estimate the prevalence of excessive daytime sleepiness in an older population and associations with sociodemographic, health, and lif... [more]

© 2013 APJPH.The aim of this research is to estimate the prevalence of excessive daytime sleepiness in an older population and associations with sociodemographic, health, and lifestyle factors using a cross-sectional, population-based study. Participants were men (1560) and women (1759), aged 55 to 85 years, enrolled in the Hunter Community Study, a longitudinal study of aging. Measurements were self-reported questionnaires, biochemical measures, and clinical measures. Of the 3319 participants, 3053 participants completed the Epworth Sleepiness Scale questionnaire. The prevalence of excessive daytime sleepiness was 15.3% overall and this was higher in males. In adjusted multivariate analysis, gender, working full time, body mass index, high-density and low-density lipoprotein cholesterol, Center for Epidemiologic Studies-Depression scale score, and Kessler psychological distress score were associated with excessive daytime sleepiness. Given the high prevalence of excessive daytime sleepiness observed in this study, further investigation and/or interventions to reduce adverse health outcomes, especially in males is warranted.

DOI 10.1177/1010539513497783
Citations Scopus - 2
Co-authors Roseanne Peel, John Attia, Milton Hasnat
2015 Hiles SA, Baker AL, de Malmanche T, McEvoy M, Boyle M, Attia J, 'The role of inflammatory markers in explaining the association between depression and cardiovascular hospitalisations', Journal of Behavioral Medicine, 38 609-619 (2015) [C1]

© 2015, Springer Science+Business Media New York.This study investigated whether inflammation may explain the relationship between depression and incident cardiovascular hospital... [more]

© 2015, Springer Science+Business Media New York.This study investigated whether inflammation may explain the relationship between depression and incident cardiovascular hospitalisations. Participants (55¿85¿years) completed baseline depression and physical assessment. Those without self-reported cardiovascular events were followed prospectively for hospital admissions for angina, myocardial infarction and cerebral infarction (median 937¿days). Across 5140 person-years of risk (N¿=¿1692), there were 47 incident cardiovascular hospitalisations (2.8¿%). Controlling for age and gender, interleukin (IL)-6, C-reactive protein (CRP), body mass index (BMI) and waist-to-hip ratio were associated with future cardiovascular events. Mediation analysis showed that CRP accounted for 8.1¿% and IL-6 10.9¿% of the effect of depression on cardiovascular events, and including the indirect effect in the model substantially reduced the direct relationship between depression and cardiovascular hospitalisations. BMI and waist-to-hip ratio accounted for indirect effects of 7.7 and 10.4¿%, respectively. Inflammatory markers partly explain the association between depression and cardiovascular events, although other shared factors also likely contribute.

DOI 10.1007/s10865-015-9637-2
Co-authors Amanda Baker, John Attia
2015 Debette S, Ibrahim Verbaas CA, Bressler J, Schuur M, Smith A, Bis JC, et al., 'Genome-wide studies of verbal declarative memory in nondemented older people: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium', Biological Psychiatry, 77 749-763 (2015) [C1]

© 2015 Society of Biological Psychiatry.BACKGROUND: Memory performance in older persons can reflect genetic influences on cognitive function and dementing processes. We aimed to ... [more]

© 2015 Society of Biological Psychiatry.BACKGROUND: Memory performance in older persons can reflect genetic influences on cognitive function and dementing processes. We aimed to identify genetic contributions to verbal declarative memory in a community setting. METHODS: We conducted genome-wide association studies for paragraph or word list delayed recall in 19 cohorts from the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium, comprising 29,076 dementia- and stroke-free individuals of European descent, aged =45 years. Replication of suggestive associations (p < 5 × 10-6) was sought in 10,617 participants of European descent, 3811 African-Americans, and 1561 young adults. RESULTS: rs4420638, near APOE, was associated with poorer delayed recall performance in discovery (p = 5.57 × 10-10) and replication cohorts (p = 5.65 × 10-8). This association was stronger for paragraph than word list delayed recall and in the oldest persons. Two associations with specific tests, in subsets of the total sample, reached genome-wide significance in combined analyses of discovery and replication (rs11074779 [HS3ST4], p = 3.11 × 10-8, and rs6813517 [SPOCK3], p = 2.58 × 10-8) near genes involved in immune response. A genetic score combining 58 independent suggestive memory risk variants was associated with increasing Alzheimer disease pathology in 725 autopsy samples. Association of memory risk loci with gene expression in 138 human hippocampus samples showed cis-associations with WDR48 and CLDN5, both related to ubiquitin metabolism. CONCLUSIONS: This largest study to date exploring the genetics of memory function in ~40,000 older individuals revealed genome-wide associations and suggested an involvement of immune and ubiquitin pathways.

DOI 10.1016/j.biopsych.2014.08.027
Citations Scopus - 6Web of Science - 1
Co-authors Peter Schofield, Christopher Oldmeadow, Rodney Scott, Liz Holliday, John Attia
2015 Sansanayudh N, Numthavaj P, Muntham D, Yamwong S, McEvoy M, Attia J, et al., 'Prognostic effect of mean platelet volume in patients with coronary artery disease: A systematic review and meta-analysis', Thrombosis and Haemostasis, 114 1299-1309 (2015) [C1]
DOI 10.1160/TH15-04-0280
Citations Scopus - 2
Co-authors John Attia
2015 Moir-Meyer GL, Pearson JF, Lose F, The ANECSG, Scott RJ, McEvoy M, et al., 'Rare germline copy number deletions of likely functional importance are implicated in endometrial cancer predisposition', Human Genetics, 134 269-278 (2015) [C1]

© 2014, Springer-Verlag Berlin Heidelberg.Endometrial cancer is the most common invasive gynaecological cancer in women, and relatively little is known about inherited risk facto... [more]

© 2014, Springer-Verlag Berlin Heidelberg.Endometrial cancer is the most common invasive gynaecological cancer in women, and relatively little is known about inherited risk factors for this disease. This is the first genome-wide study to explore the role of common and rare germline copy number variants (CNVs) in predisposition to endometrial cancer. CNVs were called from germline DNA of 1,209 endometrioid endometrial cancer cases and 528 cancer-unaffected female controls. Overall CNV load of deletions or DNA gains did not differ significantly between cases and controls (P¿>¿0.05), but cases presented with an excess of rare germline deletions overlapping likely functional genomic regions including genes (P¿=¿8¿×¿10-10), CpG islands (P¿=¿1¿×¿10-7) and sno/miRNAs regions (P¿=¿3¿×¿10-9). On average, at least one additional gene and two additional CpG islands were disrupted by rare deletions in cases compared to controls. The most pronounced difference was that over 30 sno/miRNAs were disrupted by rare deletions in cases for every single disruption event in controls. A total of 13 DNA repair genes were disrupted by rare deletions in 19/1,209 cases (1.6¿%) compared to one gene in 1/528 controls (0.2¿%; P¿=¿0.007), and this increased DNA repair gene loss in cases persisted after excluding five individuals carrying CNVs disrupting mismatch repair genes MLH1, MSH2 and MSH6 (P¿=¿0.03). There were 34 miRNA regions deleted in at least one case but not in controls, the most frequent of which encompassed hsa-mir-661 and hsa-mir-203. Our study implicates rare germline deletions of functional and regulatory regions as possible mechanisms conferring endometrial cancer risk, and has identified specific regulatory elements as candidates for further investigation.

DOI 10.1007/s00439-014-1507-4
Citations Scopus - 1
Co-authors Rodney Scott, Liz Holliday, John Attia
2015 Painter JN, O'Mara TA, Batra J, Cheng T, Lose FA, Dennis J, et al., 'Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk', HUMAN MOLECULAR GENETICS, 24 1478-1492 (2015) [C1]
DOI 10.1093/hmg/ddu552
Citations Scopus - 7Web of Science - 1
Co-authors John Attia, Katie Ashton, Rodney Scott, Liz Holliday
2015 Hancock DB, Levy JL, Gaddis NC, Glasheen C, Saccone NL, Page GP, et al., 'Cis-Expression Quantitative Trait Loci Mapping Reveals Replicable Associations with Heroin Addiction in OPRM1', Biological Psychiatry, 78 474-484 (2015) [C1]
DOI 10.1016/j.biopsych.2015.01.003
Citations Scopus - 3Web of Science - 1
Co-authors Liz Holliday, Rodney Scott, John Attia
2015 Sapkota Y, Low SK, Attia J, Gordon SD, Henders AK, Holliday EG, et al., 'Association between endometriosis and the interleukin 1A (IL1A) locus.', Human Reproduction, 30 239-248 (2015) [C1]
DOI 10.1093/humrep/deu267
Citations Scopus - 8Web of Science - 4
Co-authors Liz Holliday, John Attia, Rodney Scott
2015 Iseme RA, McEvoy M, Kelly B, Agnew L, Attia J, Walker FR, et al., 'Autoantibodies are not predictive markers for the development of depressive symptoms in a population-based cohort of older adults', European Psychiatry, 30 694-700 (2015) [C1]
DOI 10.1016/j.eurpsy.2015.06.006
Co-authors Christopher Oldmeadow, John Attia, Rohan Walker, Brian Kelly
2015 Alsalami MO, Forder PM, Milton AH, McEvoy MA, Byles JE, 'Associations Between Medication Use and Mental Health in Older Women: A Cross-Sectional Analysis of 5,502 Women Aged 76 to 81.', J Am Geriatr Soc, 63 1254-1255 (2015) [C3]
DOI 10.1111/jgs.13497
Co-authors Milton Hasnat, Julie Byles, Peta Forder
2015 O'Mara TA, Glubb DM, Painter JN, Cheng T, Dennis J, Australian National Endometrial Cancer Study Group (ANECS), et al., 'Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer.', Endocr Relat Cancer, 22 851-861 (2015) [C1]
DOI 10.1530/ERC-15-0319
Citations Scopus - 3
Co-authors John Attia, Katie Ashton, Rodney Scott, Liz Holliday
2014 Vashum KP, McEvoy M, Milton AH, McElduff P, Hure A, Byles J, Attia J, 'Dietary zinc is associated with a lower incidence of depression: findings from two Australian cohorts.', J Affect Disord, 166 249-257 (2014) [C1]
DOI 10.1016/j.jad.2014.05.016
Citations Scopus - 14Web of Science - 9
Co-authors Julie Byles, Alexis Hure, John Attia, Milton Hasnat
2014 Sotgia S, Zinellu A, Mangoni AA, Pintus G, Attia J, Carru C, McEvoy M, 'Clinical and biochemical correlates of serum L-ergothioneine concentrations in community-dwelling middle-aged and older adults', PLoS ONE, 9 (2014) [C1]

Background: Despite the increasing interest towards the biological role of L-ergothioneine, little is known about the serum concentrations of this unusual aminothiol in older adul... [more]

Background: Despite the increasing interest towards the biological role of L-ergothioneine, little is known about the serum concentrations of this unusual aminothiol in older adults. We addressed this issue in a representative sample of community-dwelling middle-aged and older adults. Methods: Body mass index, estimated glomerular filtration rate, serum concentrations of L-ergothioneine, taurine, homocysteine, cysteine, glutathione, cysteinylglycine, and glutamylcysteine were evaluated in 439 subjects (age 55-85 years) randomly selected from the Hunter Community Study. Results: Median L-ergothioneine concentration in the entire cohort was 1.01 IQR 0.78-1.33 µmol/L. Concentrations were not affected by gender (P = 0.41) or by presence of chronic medical conditions (P = 0.15). By considering only healthy subjects, we defined a reference interval for L-ergothioneine serum concentrations from 0.36 (90% CI 0.31-0.44) to 3.08 (90% CI 2.45-3.76) µmol/L. Using stepwise multiple linear regression analysis L-ergothioneine was negatively correlated with age (rpartial = 20.15; P = 0.0018) and with glutamylcysteine concentrations (rpartial = 20.13; P = 0.0063). Conclusions: A thorough analysis of serum L-ergothioneine concentrations was performed in a large group of community-dwelling middle-aged and older adults. Reference intervals were established. Age and glutamylcysteine were independently negatively associated with L-ergothioneine serum concentration. © 2014 Sotgia et al.

DOI 10.1371/journal.pone.0084918
Citations Scopus - 4Web of Science - 2
Co-authors John Attia
2014 Vashum KP, McEvoy M, Milton AH, Islam MR, Hancock S, Attia J, 'Is serum zinc associated with pancreatic beta cell function and insulin sensitivity in pre-diabetic and normal individuals? Findings from the hunter community study', PLoS ONE, 9 (2014) [C1]

Aim: To determine if there is a difference in serum zinc concentration between normoglycaemic, pre-diabetic and type-2 diabetic groups and if this is associated with pancreatic be... [more]

Aim: To determine if there is a difference in serum zinc concentration between normoglycaemic, pre-diabetic and type-2 diabetic groups and if this is associated with pancreatic beta cell function and insulin sensitivity in the former 2 groups. Method: Cross sectional study of a random sample of older community-dwelling men and women in Newcastle, New South Wales, Australia. Beta cell function, insulin sensitivity and insulin resistance were calculated for normoglycaemic and prediabetes participants using the Homeostasis Model Assessment (HOMA-2) calculator. Result: A total of 452 participants were recruited for this study. Approximately 33% (N = 149) had diabetes, 33% (N = 151) had prediabetes and 34% (N = 152) were normoglycaemic. Homeostasis Model Assessment (HOMA) parameters were found to be significantly different between normoglycaemic and prediabetes groups (p<0.001). In adjusted linear regression, higher serum zinc concentration was associated with increased insulin sensitivity (p = 0.01) in the prediabetic group. There was also a significant association between smoking and worse insulin sensitivity. Conclusion: Higher serum zinc concentration is associated with increased insulin sensitivity. Longitudinal studies are required to determine if low serum zinc concentration plays a role in progression from pre-diabetes to diabetes. © 2014 Vashum et al.

DOI 10.1371/journal.pone.0083944
Citations Scopus - 6Web of Science - 3
Co-authors John Attia, Milton Hasnat
2014 Alhazmi A, Stojanovski E, Garg ML, McEvoy M, 'Fasting whole blood fatty acid profile and risk of type 2 diabetes in adults: a nested case control study.', PLoS One, 9 e97001 (2014) [C1]
DOI 10.1371/journal.pone.0097001
Citations Scopus - 6Web of Science - 4
Co-authors Manohar Garg, Elizabeth Stojanovski
2014 Lai JS, Hiles S, Bisquera A, Hure AJ, McEvoy M, Attia J, 'A systematic review and meta-analysis of dietary patterns and depression in community-dwelling adults', AMERICAN JOURNAL OF CLINICAL NUTRITION, 99 181-197 (2014) [C1]
DOI 10.3945/ajcn.113.069880
Citations Scopus - 63Web of Science - 34
Co-authors John Attia, Alexis Hure
2014 Holliday EG, Attia J, Hancock S, Koloski N, McEvoy M, Peel R, et al., 'Genome-wide association study identifies two novel genomic regions in irritable bowel syndrome', American Journal of Gastroenterology, 109 770-772 (2014) [C1]
DOI 10.1038/ajg.2014.56
Citations Scopus - 4Web of Science - 2
Co-authors Liz Holliday, Rodney Scott, Roseanne Peel, John Attia, Nicholas Talley
2014 Iseme RA, McEvoy M, Kelly B, Agnew L, Attia J, Walker FR, 'Autoantibodies and depression. Evidence for a causal link?', Neuroscience and Biobehavioral Reviews, 40 62-79 (2014) [C1]

Depression is a leading contributor to the global burden of diseases. Despite advances in research, challenges still exist in managing this disorder. Sufferers of autoimmune disea... [more]

Depression is a leading contributor to the global burden of diseases. Despite advances in research, challenges still exist in managing this disorder. Sufferers of autoimmune diseases are often observed to suffer from depression more often than healthy individuals, an association that cannot be completely accounted for by the impact of the disease on the individual. An association between autoimmunity and depressive symptoms also appears to exist in populations with subclinical symptoms. Moreover, researchers have successfully developed murine models illustrating the ability of autoantibodies to induce depressive-like symptoms. This paper will provide an overview of the association between autoantibodies and occurrence of depressive symptoms. Though current evidence appears to support a role for autoantibodies in the pathogenesis of depression, the majority of studies have examined this relationship cross-sectionally, therefore failing to establish a temporal association. Nonetheless, this novel theory meshes with older and newer neurochemical theories of depression. A better understanding of the immuno-pathogenesis underlying depression presents opportunities for more targeted treatment approaches and more timely and appropriate measures of detection. © 2014 Elsevier Ltd.

DOI 10.1016/j.neubiorev.2014.01.008
Citations Scopus - 10Web of Science - 4
Co-authors Brian Kelly, Rohan Walker, John Attia
2014 De Vivo I, Prescott J, Setiawan VW, Olson SH, Wentzensen N, Attia J, et al., 'Genome-wide association study of endometrial cancer in E2C2', HUMAN GENETICS, 133 211-224 (2014) [C1]
DOI 10.1007/s00439-013-1369-1
Citations Scopus - 12Web of Science - 9
Co-authors Rodney Scott, John Attia, Liz Holliday
2014 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'The association between dietary patterns and type 2 diabetes: a systematic review and meta-analysis of cohort studies', JOURNAL OF HUMAN NUTRITION AND DIETETICS, 27 251-260 (2014) [C1]
DOI 10.1111/jhn.12139
Citations Scopus - 17Web of Science - 9
Co-authors Manohar Garg, Elizabeth Stojanovski
2014 Moayyeri A, Hsu Y-H, Karasik D, Estrada K, Xiao S-M, Nielson C, et al., 'Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium', HUMAN MOLECULAR GENETICS, 23 3054-3068 (2014) [C1]
DOI 10.1093/hmg/ddt675
Citations Scopus - 23Web of Science - 6
Co-authors John Attia, Christopher Oldmeadow, Liz Holliday, Rodney Scott, Roseanne Peel
2014 Wilasrusmee C, Anothaisintawee T, Poprom N, McEvoy M, Attia J, Thakkinstian A, 'Diagnostic Scores for Appendicitis: A Systematic Review of Scores¿ Performance', British Journal of Medicine and Medical Research, 4 711-730 (2014) [C1]
DOI 10.9734/BJMMR/2014/5255
Co-authors John Attia
2014 Handley TE, Hiles SA, Inder KJ, Kay-Lambkin FJ, Kelly BJ, Lewin TJ, et al., 'Predictors of Suicidal Ideation in Older People: A Decision Tree Analysis', AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 22 1325-1335 (2014) [C1]
DOI 10.1016/j.jagp.2013.05.009
Citations Scopus - 5Web of Science - 2
Co-authors Brian Kelly, Roseanne Peel, John Attia, Terry Lewin, Kerry Inder
2014 Holliday EG, Traylor M, Malik R, Bevan S, Maguire J, Koblar SA, et al., 'Polygenic Overlap Between Kidney Function and Large Artery Atherosclerotic Stroke', STROKE, 45 3508-+ (2014) [C1]
DOI 10.1161/STROKEAHA.114.006609
Citations Scopus - 1
Co-authors Jane Maguire, Chris Levi, Christopher Oldmeadow, Liz Holliday, Rodney Scott, John Attia
2014 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'Macronutrient intake and type 2 diabetes risk in middle-aged Australian women. Results from the Australian Longitudinal Study on Women's Health', PUBLIC HEALTH NUTRITION, 17 1587-1594 (2014) [C1]
DOI 10.1017/S1368980013001870
Citations Scopus - 7Web of Science - 4
Co-authors Manohar Garg, Elizabeth Stojanovski
2014 Oldmeadow C, Holliday EG, McEvoy M, Scott R, Kwok JBJ, Mather K, et al., 'Concordance between direct and imputed APOE genotypes using 1000 genomes data', Journal of Alzheimer's Disease, 42 391-393 (2014) [C1]

© 2014 - IOS Press and the authors. All rights reserved.There are a growing number of large cohorts of older persons with genome-wide genotyping data available, but APOE is not i... [more]

© 2014 - IOS Press and the authors. All rights reserved.There are a growing number of large cohorts of older persons with genome-wide genotyping data available, but APOE is not included in any of the common microarray platforms. We compared directly measured APOE genotypes with those imputed using microarray data and the '1000 Genomes' dataset in a sample of 320 Caucasians. We find 90% agreement for e2/e3/e4 genotypes and 93% agreement for predicting e4 status, yielding kappa values of 0.81 and 0.84, respectively. More stringent thresholds around allele number estimates can increase this agreement to 90-97% and kappas of 0.90-0.93.

DOI 10.3233/JAD-140846
Co-authors John Attia, Rodney Scott, Christopher Oldmeadow, Liz Holliday, Peter Schofield
2014 Muenchhoff J, Poljak A, Song F, Raftery M, Brodaty H, Duncan M, et al., 'Plasma protein profiling of mild cognitive impairment and Alzheimer's disease across two independent cohorts', Journal of Alzheimer's Disease, 43 1355-1373 (2014) [C1]

© 2015 - IOS Press and the authors.To unlock the full potential of disease modifying treatments, it is essential to develop early biomarkers for Alzheimer's disease (AD). For pra... [more]

© 2015 - IOS Press and the authors.To unlock the full potential of disease modifying treatments, it is essential to develop early biomarkers for Alzheimer's disease (AD). For practical reasons, blood-based markers that could provide a signal at the stage of mild cognitive impairment (MCI) or even earlier would be ideal. Using the proteomic approach of isobaric tagging for relative and absolute quantitation (iTRAQ), we compared the plasma protein profiles of MCI, AD, and cognitively normal control subjects from two independent cohorts: the Sydney Memory and Ageing Study (261 MCI subjects, 24 AD subjects, 411 controls) and the Hunter Community Study (180 MCI subjects, 153 controls). The objective was to identify any proteins that are differentially abundant in MCI and AD plasma in both cohorts, since they might be of interest as potential biomarkers, or could help direct future mechanistic studies. Proteins representative of biological processes relevant to AD pathology, such as the complement system, the coagulation cascade, lipid metabolism, and metal and vitamin D and E transport, were found to differ in abundance in MCI. In particular, levels of complement regulators C1 inhibitor and factor H, fibronectin, ceruloplasmin, and vitamin D-binding protein were significantly decreased in MCI participants from both cohorts. Several apolipoproteins, including apolipoprotein AIV, B-100, and H were also significantly decreased in MCI. Most of these proteins have previously been reported as potential biomarkers for AD; however, we show for the first time that a significant decrease in plasma levels of two potential biomarkers (fibronectin and C1 inhibitor) is evident at the MCI stage.

DOI 10.3233/JAD-141266
Citations Scopus - 8Web of Science - 1
Co-authors Peter Schofield, John Attia
2014 Lai JS, Attia JR, McEvoy M, Hure AJ, 'Biochemical Validation of the Older Australian¿s Food Frequency Questionnaire Using Carotenoids and Vitamin E', Nutrients, 6 4906-4917 (2014) [C1]
DOI 10.3390/nu6114906
Citations Scopus - 2
Co-authors John Attia, Alexis Hure
2014 Atiksawedparit P, Rattanasiri S, McEvoy M, Graham CA, Sittichanbuncha Y, Thakkinstian A, 'Effects of prehospital adrenaline administration on out-of-hospital cardiac arrest outcomes: a systematic review and meta-analysis', CRITICAL CARE, 18 (2014) [C1]
DOI 10.1186/s13054-014-0463-7
Citations Scopus - 5Web of Science - 2
2014 Islam MR, Attia J, Alauddin M, McEvoy M, McElduff P, Slater C, et al., 'Availability of arsenic in human milk in women and its correlation with arsenic in urine of breastfed children living in arsenic contaminated areas in Bangladesh.', Environmental Health: A Global Access Science Source, 13 1-10 (2014) [C1]
Co-authors Wayne Smith, Catherine Deste, John Attia, Roseanne Peel, Milton Hasnat
2014 McEvoy M, Schofield P, Smith W, Agho K, Mangoni AA, Soiza RL, et al., 'Memory Impairment is Associated with Serum Methylarginines in Older Adults', CURRENT ALZHEIMER RESEARCH, 11 97-106 (2014) [C1]
Citations Scopus - 4Web of Science - 3
Co-authors Peter Schofield, Roseanne Peel, John Attia, Wayne Smith
2014 Golledge J, Clancy P, Maguire J, Lincz L, Koblar S, Mcevoy M, et al., 'Plasma angiopoietin-1 is lower after ischemic stroke and associated with major disability but not stroke incidence', Stroke, 45 1064-1068 (2014) [C1]

BACKGROUND AND PURPOSE - : Studies in rodent models suggest that upregulating angiopoietin-1 (Angpt1) improves stroke outcomes. The aims of this study were to assess the associati... [more]

BACKGROUND AND PURPOSE - : Studies in rodent models suggest that upregulating angiopoietin-1 (Angpt1) improves stroke outcomes. The aims of this study were to assess the association of plasma Angpt1 with stroke occurrence and outcome. METHODS - : Plasma Angpt1 was measured in 336 patients who had experienced a recent stroke and 321 healthy controls with no stroke history. Patients with stroke (n=285) were reassessed at 3 months and plasma Angpt1 concentration on admission compared between those with severe and minor disability as assessed by the modified Rankin scale. In a separate cohort of 4032 community-acquired older men prospectively followed for a minimum of 6 years, the association of plasma Angpt1 with stroke incidence was examined. RESULTS - : Median plasma Angpt1 was 3-fold lower in patients who had experienced a recent stroke (6.42, interquartile range, 4.26-9.53 compared with 17.36; interquartile range, 14.01-22.46 ng/mL; P<0.001) and remained associated with stroke after adjustment for other risk factors. Plasma Angpt1 concentrations on admission were lower in patients who had severe disability or died at 3 months (median, 5.52; interquartile range, 3.81-8.75 ng/mL for modified Rankin scale 3-6; n=91) compared with those with minor disability (median, 7.04; interquartile range, 4.75-9.92 ng/mL for modified Rankin scale 0-2; n=194), P=0.012, and remained negatively associated with severe disability or death after adjusting for other risk factors. Plasma Angpt1 was not predictive of stroke incidence in community-dwelling older men. CONCLUSIONS - : Plasma Angpt1 concentrations are low after ischemic stroke particularly in patients with poor stroke outcomes at 3 months. Interventions effective at upregulating Angpt1 could potentially improve stroke outcomes. © 2014 American Heart Association, Inc.

DOI 10.1161/STROKEAHA.113.004339
Citations Scopus - 2Web of Science - 1
Co-authors Chris Levi, Jane Maguire, Lisa Lincz, John Attia
2014 Alhazmi A, Stojanovski E, McEvoy M, Brown W, Garg ML, 'Diet quality score is a predictor of type 2 diabetes risk in women: the Australian Longitudinal Study on Women's Health.', Br J Nutr, 112 945-951 (2014) [C1]
DOI 10.1017/S0007114514001688
Citations Scopus - 4
Co-authors Elizabeth Stojanovski, Manohar Garg
2014 Clancy P, Lincz LF, Maguire J, McEvoy M, Koblar SA, Golledge J, 'Tenascin-C is increased in atherothrombotic stroke patients and has an anti-inflammatory effect in the human carotid artery.', BioFactors (Oxford, England), 40 448-457 (2014) [C1]
Citations Scopus - 3Web of Science - 2
Co-authors Lisa Lincz, Jane Maguire
2014 Napthali K, Boyle M, Tran H, Schofield PW, Peel R, McEvoy M, et al., 'Thyroid antibodies, autoimmunity and cognitive decline: is there a population-based link?', Dement Geriatr Cogn Dis Extra, 4 140-146 (2014) [C1]
DOI 10.1159/000362716
Co-authors Peter Schofield, Christopher Oldmeadow, Roseanne Peel, John Attia
2013 Vashum KP, McEvoy M, Shi Z, Milton AH, Islam MR, Sibbritt D, et al., 'Is dietary zinc protective for type 2 diabetes? Results from the Australian longitudinal study on women's health', BMC Endocrine Disorders, 13 (2013) [C1]
DOI 10.1186/1472-6823-13-40
Citations Scopus - 4Web of Science - 3
Co-authors Julie Byles, John Attia, Milton Hasnat, Deborah Loxton, Amanda Patterson
2013 Gunathilake R, Oldmeadow C, McEvoy M, Kelly B, Inder K, Schofield P, Attia J, 'Mild Hyponatremia Is Associated With Impaired Cognition And Falls In Community-Dwelling Older Persons', Journal of the American Geriatrics Society, 61 1838-1839 (2013) [C1]
DOI 10.1111/jgs.12468
Citations Scopus - 15Web of Science - 10
Co-authors John Attia, Kerry Inder, Peter Schofield, Christopher Oldmeadow, Brian Kelly
2013 Yadav S, Cotlarciuc I, Munroe PB, Khan MS, Nalls MA, Bevan S, et al., 'Genome-Wide Analysis of Blood Pressure Variability and Ischemic Stroke', Stroke, 44 2703-2709 (2013) [C1]
DOI 10.1161/STROKEAHA.113.002186
Citations Scopus - 5Web of Science - 4
Co-authors John Attia, Jane Maguire, Rodney Scott, Liz Holliday
2013 McEvoy MA, Schofield P, Smith W, Agho K, Mangoni AA, Soiza RL, et al., 'Serum methylarginines and incident depression in a cohort of older adults', Journal of Affective Disorders, 151 493-499 (2013) [C1]
DOI 10.1016/j.jad.2013.06.033
Citations Scopus - 6Web of Science - 4
Co-authors Roseanne Peel, John Attia, Wayne Smith, Brian Kelly, Kerry Inder, Peter Schofield
2013 Rattanasiri S, McDaniel DO, McEvoy M, Anothaisintawee T, Sobhonslidsuk A, Attia J, Thakkinstian A, 'The association between cytokine gene polymorphisms and graft rejection in liver transplantation: A systematic review and meta-analysis', TRANSPLANT IMMUNOLOGY, 28 62-70 (2013) [C1]
DOI 10.1016/j.trim.2012.10.003
Citations Scopus - 3Web of Science - 1
Co-authors John Attia
2013 Courtney RJ, Paul CL, Sanson-Fisher RW, Macrae FA, Carey ML, Attia J, McEvoy M, 'Individual- and provider-level factors associated with colorectal cancer screening in accordance with guideline recommendation: a community-level perspective across varying levels of risk', BMC PUBLIC HEALTH, 13 (2013) [C1]
DOI 10.1186/1471-2458-13-248
Citations Scopus - 6Web of Science - 1
Co-authors Chris Paul, Mariko Carey, John Attia, Rob Sanson-Fisher
2013 Mangoni AA, Zinellu A, Carru C, Attia JR, McEvoy M, 'Serum thiols and cardiovascular risk scores: a combined assessment of transsulfuration pathway components and substrate/product ratios', JOURNAL OF TRANSLATIONAL MEDICINE, 11 (2013) [C1]
DOI 10.1186/1479-5876-11-99
Citations Scopus - 6Web of Science - 5
Co-authors John Attia
2013 Asif M, Soiza RL, McEvoy M, Mangoni AA, 'Asymmetric Dimethylarginine: A Possible Link between Vascular Disease and Dementia', CURRENT ALZHEIMER RESEARCH, 10 347-356 (2013) [C1]
Citations Scopus - 9Web of Science - 6
2013 Numthavaj P, Tanjararak K, Roongpuvapaht B, McEvoy M, Attia J, Thakkinstian A, 'Efficacy of Mitomycin C for postoperative endoscopic sinus surgery: a systematic review and meta-analysis', CLINICAL OTOLARYNGOLOGY, 38 198-207 (2013) [C1]
DOI 10.1111/coa.12114
Citations Scopus - 2Web of Science - 3
Co-authors John Attia
2013 Talseth-Palmer B, Holliday EG, Evans T-J, McEvoy MA, Attia JR, Grice DM, et al., 'Continuing difficulties in interpreting CNV data: Lessons from a genome-wide CNV association study of Australian HNPCC/lynch syndrome patients', BMC Medical Genomics, 6 1-13 (2013) [C1]
Citations Scopus - 7Web of Science - 4
Co-authors Liz Holliday, Bente Talseth-Palmer, Rodney Scott, John Attia
2013 Mangoni AA, Zinellu A, Carru C, Attia JR, McEvoy M, 'Transsulfuration Pathway Thiols and Methylated Arginines: The Hunter Community Study', PLOS ONE, 8 (2013) [C1]
DOI 10.1371/journal.pone.0054870
Citations Scopus - 2Web of Science - 2
Co-authors John Attia
2013 Islam MR, Arslan I, Attia J, McEvoy M, McElduff P, Basher A, et al., 'Is Serum Zinc Level Associated with Prediabetes and Diabetes?: A Cross-Sectional Study from Bangladesh', PLOS ONE, 8 (2013) [C1]
DOI 10.1371/journal.pone.0061776
Citations Scopus - 10Web of Science - 5
Co-authors Milton Hasnat, Roseanne Peel, John Attia
2013 McEvoy MA, Schofield PW, Smith WT, Agho K, Mangoni AA, Soiza RL, et al., 'Serum Methylarginines and Spirometry-Measured Lung Function in Older Adults', PLOS ONE, 8 (2013) [C1]
DOI 10.1371/journal.pone.0058390
Citations Scopus - 1
Co-authors John Attia, Roseanne Peel, Peter Schofield, Wayne Smith
2013 Sukrat B, Wilasrusmee C, Siribumrungwong B, McEvoy M, Okascharoen C, Attia J, Thakkinstian A, 'Hemoglobin Concentration and Pregnancy Outcomes: A Systematic Review and Meta-Analysis', BIOMED RESEARCH INTERNATIONAL, 1-9 (2013) [C1]
DOI 10.1155/2013/769057
Citations Scopus - 4Web of Science - 1
Co-authors John Attia
2013 Yongcharoen S, Rattanasiri S, McDaniel DO, McEvoy M, Viwatwongkaseam C, Rojanavipart P, Thakkinstian A, 'Meta-Analysis of Cytokine Gene Polymorphisms and Outcome of Heart Transplantation', BIOMED RESEARCH INTERNATIONAL, (2013) [C1]
DOI 10.1155/2013/387184
2012 Thakkinstian A, McEvoy MA, Chakravarthy U, Chakrabarti S, McKay GJ, Ryu E, et al., 'The association between complement component 2/complement factor B polymorphisms and age-related macular degeneration: A HuGE review and meta-analysis', American Journal of Epidemiology, 176 361-372 (2012) [C1]
Citations Scopus - 29Web of Science - 23
Co-authors John Attia
2012 Wilasrusmee C, Sukrat B, McEvoy MA, Attia JR, Thakkinstian A, 'Systematic review and meta-analysis of safety of laparoscopic versus open appendicectomy for suspected appendicitis in pregnancy', British Journal of Surgery, 99 1470-1478 (2012) [C1]
Citations Scopus - 24Web of Science - 17
Co-authors John Attia
2012 Courtney RJ, Paul CL, Sanson-Fisher RW, Macrae FA, Carey ML, Attia JR, McEvoy MA, 'Colorectal cancer screening in Australia: A community-level perspective', Medical Journal of Australia, 196 516-520 (2012) [C1]
Citations Scopus - 9Web of Science - 8
Co-authors Mariko Carey, John Attia, Rob Sanson-Fisher, Chris Paul
2012 Lai JS, Moxey AJ, Nowak G, Vashum KP, Bailey KA, McEvoy MA, 'The efficacy of zinc supplementation in depression: Systematic review of randomised controlled trials', Journal of Affective Disorders, 136 e31-e39 (2012) [C1]
DOI 10.1016/j.jad.2011.06.022
Citations Scopus - 40Web of Science - 29
2012 Suthers B, Hansbro PM, Thambar S, McEvoy MA, Peel R, Attia JR, 'Pneumococcal vaccination may induce anti-oxidized low-density lipoprotein antibodies that have potentially protective effects against cardiovascular disease', Vaccine, 30 3983-3985 (2012) [C1]
Citations Scopus - 6Web of Science - 5
Co-authors Roseanne Peel, John Attia, Philip Hansbro
2012 Nyholt DR, Low S-K, Anderson CA, Painter JN, Uno S, Morris AP, et al., 'Genome-wide association meta-analysis identifies new endometriosis risk loci', Nature Genetics, 44 1355-1359 (2012) [C1]
Citations Scopus - 77Web of Science - 54
Co-authors Rodney Scott, John Attia, Liz Holliday
2012 Holliday EG, Maguire JM, Evans T-J, Koblar SA, Jannes J, Sturm J, et al., 'Common variants at 6p21.1 are associated with large artery atherosclerotic stroke', Nature Genetics, 44 1147-1153 (2012) [C1]
Citations Scopus - 64Web of Science - 54
Co-authors Jane Maguire, Wayne Smith, Rodney Scott, Chris Levi, Lisa Lincz, Pablo Moscato, John Attia, Mark Parsons, Roseanne Peel, Christopher Oldmeadow, Liz Holliday
2012 Jenkins L, McEvoy MA, Patterson AJ, Sibbritt DW, 'Higher unprocessed red meat, chicken and fish intake is associated with a higher vegetable intake in mid-age non-vegetarian women', Nutrition and Dietetics, 69 293-299 (2012) [C1]
Citations Scopus - 1Web of Science - 1
Co-authors Amanda Patterson
2012 Courtney RJ, Paul CL, Sanson-Fisher RW, Macrae F, Attia JR, McEvoy MA, 'Current state of medical-advice-seeking behaviour for symptoms of colorectal cancer: determinants of failure and delay in medical consultation', Colorectal Disease, 14 e222-e229 (2012) [C1]
Citations Scopus - 11Web of Science - 5
Co-authors Rob Sanson-Fisher, Chris Paul, John Attia
2012 Courtney RJ, Paul CL, Sanson-Fisher RW, Macrae FA, Carey ML, Attia JR, McEvoy MA, 'Colorectal cancer risk assessment and screening recommendation: A community survey of healthcare providers' practice from a patient perspective', BMC Family Practice, 13 1-9 (2012) [C1]
Citations Scopus - 2Web of Science - 2
Co-authors Rob Sanson-Fisher, Chris Paul, John Attia, Mariko Carey
2012 Courtney RJ, Paul CL, Sanson-Fisher RW, Macrae FA, Attia JR, McEvoy MA, 'Factors associated with consultation behaviour for primary symptoms potentially indicating colorectal cancer: A cross-sectional study on response to symptoms', BMC Gastroenterology, 12 1-9 (2012) [C1]
Citations Scopus - 8Web of Science - 5
Co-authors Chris Paul, John Attia, Rob Sanson-Fisher
2012 Islam MR, Khan I, Hassan SMN, McEvoy MA, D'Este CA, Attia JR, et al., 'Association between type 2 diabetes and chronic arsenic exposure in drinking water: A cross sectional study in Bangladesh', Environmental Health, 11 1-8 (2012) [C1]
Citations Scopus - 27Web of Science - 8
Co-authors Milton Hasnat, John Attia, Roseanne Peel, Catherine Deste
2012 Alhazmi AH, Stojanovski E, McEvoy MA, Garg ML, 'Macronutrient intakes and development of type 2 diabetes: A systematic review and meta-analysis of cohort studies', Journal of the American College of Nutrition, 31 243-258 (2012) [C1]
Citations Scopus - 16Web of Science - 8
Co-authors Elizabeth Stojanovski, Manohar Garg
2012 Islam MR, Khan I, Attia JR, Hassan SMN, McEvoy MA, D'Este CA, et al., 'Association between hypertension and chronic arsenic exposure in drinking water: A cross-sectional study in Bangladesh', International Journal of Environmental Research and Public Health, 9 4522-4536 (2012) [C1]
Citations Scopus - 11Web of Science - 5
Co-authors Milton Hasnat, John Attia, Catherine Deste
2011 Moxey AJ, McEvoy MA, Bowe SJ, Attia JR, 'Spirituality, religion, social support and health among older Australian adults', Australasian Journal on Ageing, 30 82-88 (2011) [C1]
DOI 10.1111/j.1741-6612.2010.00453.x
Citations Scopus - 8Web of Science - 3
Co-authors John Attia
2011 Thakkinstian A, McKay GJ, McEvoy MA, Chakravarthy U, Chakrabarti S, Silvestri G, et al., 'Systematic review and meta-analysis of the association between complement component 3 and age-related macular degeneration: A HuGE review and meta-analysis', American Journal of Epidemiology, 173 1365-1379 (2011) [C1]
DOI 10.1093/aje/kwr025
Citations Scopus - 53Web of Science - 41
Co-authors John Attia
2011 Anothaisintawee T, Attia JR, Nickel JC, Thammakraisorn S, Numthavaj P, McEvoy MA, Thakkinstian A, 'Management of chronic prostatitis/ Chronic pelvic pain syndrome: A systematic review and network meta-analysis', JAMA: The Journal of the American Medical Association, 305 78-86 (2011) [C1]
DOI 10.1001/jama.2010.1913
Citations Scopus - 79Web of Science - 57
Co-authors John Attia
2010 Proietto AM, Otton GR, Symonds IM, McEvoy MA, Attia JR, Gilbert M, et al., 'Polymorphisms in genes of the steroid hormone biosynthesis and metabolism pathways and endometrial cancer risk', Cancer Epidemiology, 34 328-337 (2010) [C1]
DOI 10.1016/j.canep.2010.03.005
Citations Scopus - 31Web of Science - 27
Co-authors Rodney Scott, John Attia, Ian Symonds, Katie Ashton
2010 Smith DR, Attia JR, McEvoy MA, 'Exploring new frontiers in occupational epidemiology: The Hunter Community Study (HCS) from Australia', Industrial Health, 48 244-248 (2010) [C1]
DOI 10.2486/indhealth.48.244
Citations Scopus - 5Web of Science - 5
Co-authors John Attia
2010 Schofield PW, Lee SJ, Lewin TJ, Lyall G, Moyle J, Attia JR, McEvoy MA, 'The Audio Recorded Cognitive Screen (ARCS): A flexible hybrid cognitive test instrument', Journal of Neurology Neurosurgery and Psychiatry, 81 602-607 (2010) [C1]
DOI 10.1136/jnnp.2009.188003
Citations Scopus - 15Web of Science - 11
Co-authors John Attia, Peter Schofield, Terry Lewin
2010 Kamanamool N, McEvoy MA, Attia JR, Ingsathit A, Ngamjanyaporn P, Thakkinstian A, 'Efficacy and adverse events of mycophenolate mofetil versus cyclophosphamide for induction therapy of lupus nephritis: Systematic review and meta-analysis', Medicine, 89 227-235 (2010) [C1]
DOI 10.1097/MD.0b013e3181e93d00
Citations Scopus - 38Web of Science - 25
Co-authors John Attia
2010 McEvoy MA, Smith WT, D'Este CA, Duke JM, Peel R, Schofield PW, et al., 'Cohort Profile: The Hunter Community Study', International Journal of Epidemiology, 39 1452-1463 (2010) [C1]
DOI 10.1093/ije/dyp343
Citations Scopus - 67Web of Science - 58
Co-authors Julie Byles, Wayne Smith, Catherine Deste, Peter Schofield, Mddah01, Roseanne Peel, John Attia, Ben Ewald, Rodney Scott
2010 Ewald BD, McEvoy MA, Attia JR, 'Pedometer counts superior to physical activity scale for identifying health markers in older adults', British Journal of Sports Medicine, 44 756-761 (2010) [C1]
DOI 10.1136/bjsm.2008.048827
Citations Scopus - 15Web of Science - 9
Co-authors John Attia, Ben Ewald
2010 Wood LG, Attia JR, McElduff P, McEvoy MA, Gibson PG, 'Assessment of dietary fat intake and innate immune activation as risk factors for impaired lung function', European Journal of Clinical Nutrition, 64 818-825 (2010) [C1]
DOI 10.1038/ejcn.2010.68
Citations Scopus - 6Web of Science - 5
Co-authors John Attia, Lisa Wood, Peter Gibson
2010 Arj-Ong S, Thakkinstian A, McEvoy MA, Attia JR, 'A systematic review and meta-analysis of tumor necrosis factor alpha-308 polymorphism and Kawasaki disease', Pediatrics International, 52 527-532 (2010) [C1]
DOI 10.1111/j.1442-200X.2010.03105.x
Citations Scopus - 13Web of Science - 10
Co-authors John Attia
2010 Ashton KA, Proietto AM, Otton GR, Symonds IM, McEvoy MA, Attia JR, Scott R, 'Toll-Like Receptor (TLR) and Nucleosome-binding Oligomerization Domain (NOD) gene polymorphisms and endometrial cancer risk', BMC Cancer, 10 1-7 (2010) [C1]
DOI 10.1186/1471-2407-10-382
Citations Scopus - 26Web of Science - 24
Co-authors Katie Ashton, Ian Symonds, John Attia, Rodney Scott
2009 Ashton KA, Proietto AM, Otton GR, Symonds IM, McEvoy MA, Attia JR, et al., 'Estrogen receptor polymorphisms and the risk of endometrial cancer', BJOG: An International Journal of Obstetrics and Gynaecology, 116 1053-1061 (2009) [C1]
DOI 10.1111/j.1471-0528.2009.02185.x
Citations Scopus - 30Web of Science - 26
Co-authors John Attia, Ian Symonds, Katie Ashton, Rodney Scott
2009 Ashton KA, Proietto AM, Otton GR, Symonds IM, McEvoy MA, Attia JR, et al., 'Polymorphisms in TP53 and MDM2 combined are associated with high grade endometrial cancer', Gynecologic Oncology, 113 109-114 (2009) [C1]
DOI 10.1016/j.ygyno.2008.12.036
Citations Scopus - 28Web of Science - 26
Co-authors Katie Ashton, Rodney Scott, John Attia, Ian Symonds
2009 Attia JR, Ioannidis JPA, Thakkinstian A, McEvoy MA, Scott R, Minelli C, et al., 'How to use an article about genetic association A: Background concepts', JAMA: Journal of the American Medical Association, 301 74-81 (2009) [C1]
DOI 10.1001/jama.2008.901
Citations Scopus - 61Web of Science - 56
Co-authors Rodney Scott, John Attia
2009 Attia JR, Ioannidis JPA, Thakkinstian A, McEvoy MA, Scott R, Minelli C, et al., 'How to use an article about genetic association B: Are the results of the study valid?', JAMA: Journal of the American Medical Association, 301 191-197 (2009) [C1]
DOI 10.1001/jama.2008.946
Citations Scopus - 91Web of Science - 87
Co-authors Rodney Scott, John Attia
2009 Attia JR, Ioannidis JPA, Thakkinstian A, McEvoy MA, Scott R, Minelli C, et al., 'How to use an article about genetic association C: What are the results and will they help me in caring for my patients?', JAMA: Journal of the American Medical Association, 301 304-308 (2009) [C1]
DOI 10.1001/jama.2008.993
Citations Scopus - 46Web of Science - 39
Co-authors John Attia, Rodney Scott
2008 Ashton KA, Proietto AM, Otton GR, Symonds IM, McEvoy MA, Attia JR, et al., 'The influence of the Cyclin D1 870 G>A polymorphism as an endometrial cancer risk factor', BMC Cancer, 8 1-6 (2008) [C1]
DOI 10.1186/1471-2407-8-272
Citations Scopus - 8Web of Science - 6
Co-authors John Attia, Ian Symonds, Katie Ashton, Rodney Scott
2008 Shi Z, McEvoy MA, Luu J, Attia JR, 'Dietary fat and sleep duration in Chinese men and women', International Journal of Obesity, 32 1835-1840 (2008) [C1]
DOI 10.1038/ijo.2008.191
Citations Scopus - 32Web of Science - 26
Co-authors John Attia
2008 Thakkinstian A, Dmitrienko S, Gerbase-Delima M, McDaniel DO, Inigo P, Chow KM, et al., 'Association between cytokine gene polymorphisms and outcomes in renal transplantation: A meta-analysis of individual patient data', Nephrology Dialysis Transplantation, 23 3017-3023 (2008) [C1]
DOI 10.1093/ndt/gfn185
Citations Scopus - 34Web of Science - 30
Co-authors John Attia
2007 Honoki K, Stojanovski E, McEvoy MA, Fujii H, Tsujiuchi T, Kido A, et al., 'Prognostic significance of p16(INK4a) alteration for Ewing sarcoma - A meta-analysis', Cancer, 110 1351-1360 (2007) [C1]
DOI 10.1002/cncr.22908
Citations Scopus - 21Web of Science - 16
Co-authors Elizabeth Stojanovski, John Attia
2007 Duke JM, McEvoy MA, Sibbritt DW, Guest M, Smith WT, Attia JR, 'Vibrotactile threshold measurement for detecting peripheral neuropathy: Defining variability and a normal range for clinical and research use', Diabetologia, 50 2305-2312 (2007) [C1]
DOI 10.1007/s00125-007-0813-y
Citations Scopus - 18Web of Science - 16
Co-authors John Attia, Wayne Smith
2006 Thakkinstian A, Han PY, McEvoy MA, Smith WT, Hoh J, Magnusson K, et al., 'Systematic review and meta-analysis of the association between complementary factor HY402H polymorphisms and age-related macular degeneration', Human Molecular Genetics, 15 2784-2790 (2006) [C1]
DOI 10.1093/hmg/ddl220
Citations Scopus - 155Web of Science - 134
Co-authors Wayne Smith, John Attia
2006 Thakkinstian A, Bowe SJ, McEvoy MA, Smith WT, Attia JR, 'Association between apolipoprotein E polymorphisms and age-related macular degeneration: A HuGE review and meta-analysis', American Journal of Epidemiology, 164 813-822 (2006) [C1]
DOI 10.1093/aje/kwj279
Citations Scopus - 58Web of Science - 46
Co-authors John Attia, Wayne Smith
2005 Thakkinstian A, McEvoy MA, Minelli C, Gibson PG, Hancox B, Duffy D, et al., 'Systematic review and meta-analysis of the association between beta(2)-adrenoceptor polymorphisms and asthma: A HuGE review', American Journal of Epidemiology, 162 201-211 (2005) [C1]
DOI 10.1093/aje/kwi184
Citations Scopus - 248Web of Science - 229
Co-authors Peter Gibson, John Attia
Show 107 more journal articles

Conference (26 outputs)

Year Citation Altmetrics Link
2015 Percival E, Bhatia R, McElduff P, McEvoy M, Collison A, Mattes J, 'REPRODUCIBILITY OF ARA h2 SKIN PRICK TESTING AND FRACTION OF EXHALED NITRIC OXIDE IN THE ASSESSMENT OF PAEDIATRIC PEANUT ALLERGY', INTERNAL MEDICINE JOURNAL (2015) [E3]
Co-authors Joerg Mattes
2014 Alsalami M, Forder P, Byles J, Hasnat MA, McEvoy M, 'The association between classes of different medications and mental health outcome in 5502 women aged 76-81 years old', 15th International Mental Health Conference (2014) [E3]
Co-authors Peta Forder, Milton Hasnat, Julie Byles
2014 Mather KA, Thalamuthu A, Oldmeadow C, Song F, Armstrong NJ, Poljak A, et al., 'Genome-wide significant results identified for plasma apolipoprotein h levels', Alzheimer's & Dementia (2014) [E3]
DOI 10.1016/j.jalz.2014.05.1526
Co-authors Peter Schofield, Liz Holliday, Christopher Oldmeadow, John Attia, Rodney Scott
2014 Bolton KA, Holliday EG, McEvoy M, Attia J, Proietto A, Otton G, et al., 'A highly polymorphic AG repeat in the upstream regulatory region of the estrogen gene EIG121 is a potential modifier of endometrial cancer risk.', Asia-Pacific Journal of Clinical Oncology (2014) [E3]
DOI 10.1111/ajco.12335
Co-authors Liz Holliday, Nikola Bowden, Kelly Kiejda, Rodney Scott, John Attia
2014 Lai J, Hure A, McEvoy M, Byles J, Attia J, 'Diet Quality And Depressive Symptoms In Mid-age Australian Women: Results From Preliminary Analysis', International Society for Affective Disorders Oral Abstract Book (2014) [E3]
Co-authors John Attia, Julie Byles, Alexis Hure
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'High quality diet associated with a lower risk of type 2 diabetes', Proceedings of The Australian Diabetes Society (ADS) and Australian Diabetes Educators Association (ADEA) annual scientific meeting (2013) [E3]
Co-authors Manohar Garg, Elizabeth Stojanovski
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'Australian diet quality scores as predictors of type 2 diabetes risk', Proceedings of The Nutrition Society of Australia and Nutrition Society of New Zealand Joint Annual Scientific Meeting (2013) [E3]
Co-authors Manohar Garg, Elizabeth Stojanovski
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'Dietary fatty acid intake in relation to type 2 diabetes risk', Proceedings of the 2nd American Society For Nutrition (2013) [E3]
Co-authors Elizabeth Stojanovski, Manohar Garg
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'Is macronutrient intake associated with development of type 2 diabetes?', Proceedings of the 2nd American Society For Nutrition Middle East Congress, Dubai, UAE, February 2013, Meeting (2013) [E3]
Co-authors Manohar Garg, Elizabeth Stojanovski
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'Evaluation of macronutrient intake in relation to type 2 diabetes risk', Proceedings of the 7th International DIP Symposium on Diabetes, Hypertension, Metabolic Syndrome, and Pregnancy (2013) [E3]
Co-authors Elizabeth Stojanovski, Manohar Garg
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'Association between whole blood omega-3 fatty acids and type 2 diabetes', Proceedings of the Australasian Section of the American Oil Chemists' Society Biannual meeting (2013) [E3]
Co-authors Manohar Garg, Elizabeth Stojanovski
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'Whole blood fatty acid profile and incidence of type 2 diabetes in older Australians', Proceedings of the Nutrition Society of Australia and Nutrition Society of New Zealand Joint Annual Scientific Meeting (2013) [E3]
Co-authors Elizabeth Stojanovski, Manohar Garg
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'Total carbohydrate intake does not predict type 2 diabetes risk in mid-age women', Proceedings of the The Australian Diabetes Society (ADS) and Australian Diabetes Educators Association (ADEA) annual scientific meeting (2013) [E3]
Co-authors Manohar Garg, Elizabeth Stojanovski
2013 Alhazmi A, Stojanovski E, McEvoy M, Garg ML, 'A prospective analysis of diet quality and type 2 diabetes risk', Proceedings of the World Diabetes Congress (2013) [E3]
Co-authors Elizabeth Stojanovski, Manohar Garg
2013 Lai JS, Hiles S, Hure AJ, McEvoy M, Attia J, 'SYSTEMATIC REVIEW AND META-ANALYSIS OF DIETARY PATTERNS AND DEPRESSION: OBSERVATIONAL STUDIES', ANNALS OF NUTRITION AND METABOLISM (2013) [E3]
Co-authors Alexis Hure, John Attia
2013 Nyholt DR, Low S-K, Anderson CA, Painter JN, Uno S, Morris AP, et al., 'Meta-Analysis of GWA Studies Identifies New Endometriosis Risk Loci', REPRODUCTIVE SCIENCES (2013) [E3]
Co-authors Liz Holliday, John Attia, Rodney Scott
2012 Islam MR, Khan I, Hassan SMN, McEvoy MA, D'Este CA, Attia JR, et al., 'Association between hypertension and chronic exposure in Bangladesh', Hypertension (2012) [E3]
Co-authors John Attia, Catherine Deste, Milton Hasnat
2012 Talseth-Palmer B, Holliday EG, Evans T-J, McEvoy MA, Attia JR, Grice DM, et al., 'A genome-wide CNV association study of Australian HNPCC/Lynch syndrome patients', Proceedings of the Australian Health & Medical Research Congress 2012 (2012) [E3]
Co-authors John Attia, Rodney Scott, Bente Talseth-Palmer, Liz Holliday
2011 Courtney RJ, Paul CL, Sanson-Fisher RW, Macrae FA, Carey ML, Attia JR, McEvoy MA, 'Colorectal cancer screening in Australia: A community-level perspective', Asia-Pacific Journal of Clinical Oncology: COSA 38th Annual Scientific Meeting Poster Abstracts (2011) [E3]
DOI 10.5694/mja11.10661
Co-authors John Attia, Mariko Carey, Rob Sanson-Fisher, Chris Paul
2011 Alhazmi AH, Stojanovski E, McEvoy MA, Garg ML, 'Omega-3 fatty acid intake and incidence of type 2 diabetes', Australasian Medical Journal (2011) [E3]
Co-authors Elizabeth Stojanovski, Manohar Garg
2011 Alhazmi AH, Stojanovski E, McEvoy MA, Garg ML, 'Association between dietary pattern and type 2 diabetes: A systematic literature review and meta-analysis', Australasian Medical Journal (2011) [E3]
Co-authors Manohar Garg, Elizabeth Stojanovski
2011 Patterson AJ, Jenkins L, McEvoy MA, Sibbritt DW, 'Fresh meat and fish intake is associated with a higher vegetable intake in mid-age non-vegetarian women', 2011 Annual Meeting of the International Society for Behavioral Nutrition and Physical Activity (ISBNPA) eProceedings (2011) [E3]
Co-authors Amanda Patterson
2011 Khan I, Hassan S, McEvoy MA, D'Este CA, Attia JR, Peel R, Hasnat MA, 'Association between type 2 diabetes and chronic arsenic exposure in Bangladesh', Epidemiology (2011) [E3]
Citations Web of Science - 2
Co-authors John Attia, Roseanne Peel, Milton Hasnat, Catherine Deste
2010 Talseth-Palmer B, Holliday EG, Evans T-J, McPhillips M, McEvoy MA, Attia JR, Scott R, 'A modern approach to the search for modifying genetic loci infleuncing the high breast cancer incidence seen in an Australian HNPCC/Lynch Syndrome cohort', Proceedings of the Australian Health and Medical Research Congress 2010 (2010) [E3]
Co-authors John Attia, Rodney Scott, Bente Talseth-Palmer, Liz Holliday
2008 Wood LG, Attia JR, McElduff P, McEvoy MA, Flood V, Gibson PG, 'Dietary fat and an activated innate immune response are associated with reduced FEV1', Asia Pacific Journal of Clinical Nutrition (2008) [E3]
Co-authors John Attia, Lisa Wood, Peter Gibson
2008 Ashton KA, Proietto AM, Otton GR, Symonds IM, McEvoy MA, Attia JR, et al., 'Combined tp53 r72p and mdm2 snp309 genotypes are associated with high grade endometrial cancer', ASMR XVII NSW Scientific Meeting: Programme and Abstracts (2008) [E3]
Co-authors Katie Ashton, Ian Symonds, Rodney Scott, John Attia
Show 23 more conferences
Edit

Grants and Funding

Summary

Number of grants 13
Total funding $2,107,336

Click on a grant title below to expand the full details for that specific grant.


20151 grants / $20,000

Jennie Thomas Medical Research Travel Grant$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Mark McEvoy, Laureate Professor Nick Talley, Professor Sven Pettersson, Mr Zachary Mcpherson
Scheme Jennie Thomas Medical Research Travel Grant
Role Lead
Funding Start 2015
Funding Finish 2016
GNo G1500643
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20141 grants / $1,815,627

Does pneumococcal vaccination protect against cardiovascular disease? $1,815,627

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor John Attia, Professor Catherine D'Este, Dr Walter Abhayaratna, Professor Andrew Tonkin, Conjoint Professor Chris Levi, Conjoint Professor David Durrheim, Professor Joseph Hung, Associate Professor Mark McEvoy, Doctor Alexis Hure
Scheme Project Grant
Role Investigator
Funding Start 2014
Funding Finish 2018
GNo G1300127
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

20121 grants / $25,000

Validation of the food frequency questionnaire used in the Hunter Community Study using carotenoids and fatty acids$25,000

Funding body: John Hunter Hospital Charitable Trust

Funding body John Hunter Hospital Charitable Trust
Project Team Doctor Alexis Hure, Professor John Attia, Associate Professor Mark McEvoy
Scheme Research Grant
Role Investigator
Funding Start 2012
Funding Finish 2012
GNo G1200266
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

20103 grants / $46,483

Delay in seeking treatment for symptoms of bowel cancer: a community survey of self-reported delay timeframes and triggers for seeking treatment among those aged 55+$21,485

Funding body: Hunter Children`s Research Foundation

Funding body Hunter Children`s Research Foundation
Project Team Associate Professor Christine Paul, Laureate Professor Robert Sanson-Fisher, Doctor Mariko Carey, Mr Ryan Courtney, Conjoint Professor Cate d'Este, Associate Professor Mark McEvoy
Scheme Research Grant
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo G0900147
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Zinc as a target for prevention of type-2 diabetes$15,000

Funding body: Hunter Children`s Research Foundation

Funding body Hunter Children`s Research Foundation
Project Team Professor John Attia, Doctor Milton Hasnat, Associate Professor Mark McEvoy, Doctor Amanda Patterson, Doctor Sham Acharya, Mr Steven Bowe
Scheme Research Grant
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo G1000450
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Genetic influences in colorectal cancer: a global consortium$9,998

Funding body: Hunter Children`s Research Foundation

Funding body Hunter Children`s Research Foundation
Project Team Professor Rodney Scott, Professor John Attia, Associate Professor Mark McEvoy
Scheme Research Grant
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo G0900152
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20091 grants / $48,600

Study of arsenic in human milk and assessment of human milk intake living in arsenic contaminated areas in Bangladesh$48,600

Funding body: International Atomic Energy Agency

Funding body International Atomic Energy Agency
Project Team Doctor Milton Hasnat, Associate Professor Mark McEvoy, Mr Md Rahman, S Shahidullah, Dr Nazmul Hassan
Scheme Coordinated Research Project
Role Investigator
Funding Start 2009
Funding Finish 2011
GNo G0190481
Type Of Funding International - Competitive
Category 3IFA
UON Y

20072 grants / $57,678

Prevention of heart disease by pneumococcal vaccination$50,000

Funding body: Pfizer Australia

Funding body Pfizer Australia
Project Team Professor Phil Hansbro, Dr Sukumaran Thambar, Professor John Attia, Associate Professor Mark McEvoy
Scheme Cardiovascular Lipid Research Grants
Role Investigator
Funding Start 2007
Funding Finish 2007
GNo G0186642
Type Of Funding Aust Competitive - Non Commonwealth
Category 1NS
UON Y

The impact of Asymmetrical Dimethylarginine on Cognition in a population-based cohort$7,678

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Mark McEvoy, Conjoint Professor Wayne Smith, Conjoint Associate Professor Peter Schofield, Professor John Attia
Scheme Pilot Grant
Role Lead
Funding Start 2007
Funding Finish 2007
GNo G0187872
Type Of Funding Internal
Category INTE
UON Y

20064 grants / $93,948

Prevention of heart disease by pneumococcal vaccination$55,000

Funding body: Pfizer Australia

Funding body Pfizer Australia
Project Team

Dr Suku Thambar

Scheme Cardiovascular Lipid Research Grants
Role Investigator
Funding Start 2006
Funding Finish 2007
GNo
Type Of Funding External
Category EXTE
UON N

The impact of Anticholinergic activity, apolipoprotein E and high-affinity choline transporter genotype on cognition in a population-based co-hort: a pilot study$15,500

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Mark McEvoy, Conjoint Associate Professor Peter Schofield, Conjoint Professor Wayne Smith, Doctor Janine Duke, Professor John Attia
Scheme Project Grant
Role Lead
Funding Start 2006
Funding Finish 2006
GNo G0186170
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Is pneumococcal vaccination protective for cardiovascular disease? Elucidating the relationship between pneumococcal vaccination and protective anti-oxidised LDL antibodies.$13,448

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team

Profesor John Attia

Scheme Pilot Scheme
Role Investigator
Funding Start 2006
Funding Finish 2007
GNo
Type Of Funding Internal
Category INTE
UON N

The impact of Anticholinergic Activity on cognition in a population-based cohort$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Conjoint Associate Professor Peter Schofield, Conjoint Professor Wayne Smith, Conjoint Professor Ian Whyte, Conjoint Professor David Sibbritt, Associate Professor Mark McEvoy
Scheme Near Miss Grant
Role Investigator
Funding Start 2006
Funding Finish 2006
GNo G0186077
Type Of Funding Internal
Category INTE
UON Y
Edit

Research Supervision

Number of supervisions

Completed4
Current9

Total current UON EFTSL

Masters0.6
PhD1.95

Current Supervision

Commenced Level of Study Research Title / Program / Supervisor Type
2016 PhD Metabolically Healthy Obesity and Its Association with Adverse Health Outcomes
PhD (CommunityMed & ClinEpid), Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2016 Masters Myelodysplastic Syndromes
M Philosophy (Medicine), Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2016 Masters A Healthy Living Program for Australians Living with Psychosis
M Philosophy (ComMed&ClinEpid), Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2016 Masters A Healthy Living Program for Australians Living with Psychosis
M Philosophy (Nutrition&Diet), Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2016 PhD Which Patients Progress to Diabetes the `Metabolically Healthy Obese' or `Metabolically Unhealthy Normal Weight'? Can this be Predicated by the use of Biomarkers to Identify High Risk Patients at Need of Early Intervention?
PhD (CommunityMed & ClinEpid), Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2015 PhD The Potential Role of the Gastrointestinal Microbiome in Neuroprotection: Analysis of a Potential Risk Factor for Glaucoma and a Potential Prognostic Factor for Stroke, and an Investigation of Potential Mechanisms in Mice
PhD (Medicine), Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2015 PhD Dietary Nitrates and Cardiovascular Health
PhD (Nutrition & Dietetics), Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2012 PhD The Role of Autoantibodies in the Development of Depression
PhD (CommunityMed & ClinEpid), Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2011 PhD Medications Use and Mental Health Outcome
PhD (Gender & Health), Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor

Past Supervision

Year Level of Study Research Title / Program / Supervisor Type
2016 PhD Diet and Depression in Community-Dwelling Adults
PhD (CommunityMed & ClinEpid), Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2015 PhD The Role of Zinc in Chronic Disease
PhD (CommunityMed & ClinEpid), Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2014 PhD Association of Dietary Patterns and Macronutrient Intake with Type 2 Diabetes Risk
PhD (Nutrition & Dietetics), Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2014 PhD Availability of Arsenic in Breast Milk, Effect of Chronic Arsenic Exposure on Type2 Diabetes, Hypertension in Adults and on Children's Nutritional Status in Bangladesh
PhD (CommunityMed & ClinEpid), Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
Edit

Research Collaborations

The map is a representation of a researchers co-authorship with collaborators across the globe. The map displays the number of publications against a country, where there is at least one co-author based in that country. Data is sourced from the University of Newcastle research publication management system (NURO) and may not fully represent the authors complete body of work.

Country Count of Publications
Australia 110
United Kingdom 31
United States 29
Germany 18
Thailand 18
More...
Edit

Associate Professor Mark McEvoy

Position

Associate Professor
CCEB
School of Medicine and Public Health
Faculty of Health and Medicine

Focus area

Public Health

Contact Details

Email mark.mcevoy@newcastle.edu.au
Phone 404 20518

Office

Building Level 3 Hunter Medical Research Institute
Edit