Staff Profile
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Career Summary
Biography
Dr Spratt leads the stroke translation laboratory within the school of Biomedical Sciences and Pharmacy, and also works as a clinical neurologist at John Hunter Hospital. He sees his role primarily as 'bridging the gap' in translational stroke research, with the aims of moving promising therapies from the laboratory into clinical use, and of answering those important clinical questions best addressed with laboratory research. His group is part of the Hunter Medical Research Institute Centre for Brain and Mental Health stroke stream and work closely with clinical, imaging and epidemiological researchers from this stream.
Qualifications
- PhD (Medicine Denistry & Health Sciences), University of Melbourne, 19/09/2007
- Bachelor of Medicine (Honours), University of Newcastle, 27/04/1995
- Bachelor of Medical Science (Honours), University of Newcastle, 01/05/1993
Research
Research keywords
- Clinical Science
- Enriched Environment
- Experimental Stroke
- Hypothermia
- Neurosciences
- Stroke
- intracranial pressure
Research expertise
- New stroke treatment: Hypothermia
- Intracranial Pressure and CSF flow regulation after stroke
- Leptomeningeal Collateral supply to the stroke ischaemic penumbra - potential therapeutics
- Understanding basic mechanisms of brain injury in stroke role of CaMKII
- Sonothrombolysis for acute stroke.
- Acute stroke clinical trials - new thrombolytics, new therapies for intracranial haemorrhage
- Improved patient selection for stroke therapy with advanced CT imaging
- Evaluation and translation of effective stroke rehabilitation strategies from the laboratory into the rehabilitation hospital:
- Environmental Enrichment
- Improving cardiovascular fitness
Fields of Research
| Code | Description | Percentage |
|---|---|---|
| 110904 | Neurology And Neuromuscular Diseases | 40 |
| 060805 | Animal Neurobiology | 35 |
| 060603 | Animal Physiology - Systems | 25 |
Appointments
| Health Professional Research Fellowship (Part-time) School of Biomedical Sciences and Pharmacy (Australia) | 01/01/2007 - 01/01/2011 |
| Fellow NHMRC School of Biomedical Sciences and Pharmacy (Australia) | 01/01/2012 - 01/12/2015 |
Administrative
Administrative expertise
Course Co-ordinator Yr 1 Semester 2 Medical Science
Co-chair - Stroke Stream - Priority Research Centre for Translational Neuroscience and Mental Health
Teaching
Teaching keywords
- Biomedical Sciences - Neuroscience
- Medical Physiology
- Pharmacy - Stroke
Teaching expertise
Neuroscience - Stroke
Pharmacology of Stroke
Medical Science - Physiology
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Publications
For publications that are currently unpublished or in-press, details are shown in italics.
Click on a category title below to expand the list of citations for that specific category.
Journal article (49 outputs)
| Year | Citation | Altmetrics | Link |
|---|---|---|---|
| 2015 | Dunn A, Marsden DL, Nugent E, Van Vliet P, Spratt NJ, Attia J, Callister R, 'Protocol variations and six-minute walk test performance in stroke survivors: A systematic review with meta-analysis', Stroke Research and Treatment, 2015 (2015) DOI: 10.1155/2015/484813 Co-authors: JOHN ATTIA, PAULETTE VANVLIET, ROBIN CALLISTER | ||
| 2015 | Beard DJ, McLeod DD, Logan CL, Murtha LA, Imtiaz MS, van Helden DF, Spratt NJ, 'Intracranial pressure elevation reduces flow through collateral vessels and the penetrating arterioles they supply. A possible explanation for 'collateral failure' and infarct expansion after ischemic stroke.', J Cereb Blood Flow Metab, (2015) DOI: 10.1038/jcbfm.2015.2 | Author URL Co-authors: DAMIAN MCLEOD | ||
| 2015 | Tomkins AJ, Schleicher N, Murtha L, Kaps M, Levi CR, Nedelmann M, Spratt NJ, 'Platelet rich clots are resistant to lysis by thrombolytic therapy in a rat model of embolic stroke.', Exp Transl Stroke Med, 7 2 (2015) DOI: 10.1186/s13231-014-0014-y | Author URL Co-authors: CHRIS LEVI | ||
| 2014 | Spratt NJ, Tomkins AJ, Pepperall D, McLeod DD, Calford MB, 'Allopregnanolone and its precursor progesterone do not reduce injury after experimental stroke in hypertensive rats - role of postoperative temperature regulation?', PLoS One, 9 e107752 (2014) [C1] DOI: 10.1371/journal.pone.0107752 | Author URL Co-authors: DAMIAN MCLEOD | ||
| 2014 | Egan KJ, Janssen H, Sena ES, Longley L, Speare S, Howells DW, et al., 'Exercise reduces infarct volume and facilitates neurobehavioral recovery: Results from a systematic review and meta-analysis of exercise in experimental models of focal ischemia', Neurorehabilitation and Neural Repair, 28 800-812 (2014) [C1] | ||
| 2014 | Murtha LA, Yang Q, Parsons MW, Levi CR, Beard DJ, Spratt NJ, McLeod DD, 'Cerebrospinal fluid is drained primarily via the spinal canal and olfactory route in young and aged spontaneously hypertensive rats', Fluids and Barriers of the CNS, 11 (2014) [C1] Co-authors: CHRIS LEVI, DAMIAN MCLEOD, mark parsons | ||
| 2014 | White JH, Alborough K, Janssen H, Spratt N, Jordan L, Pollack M, 'Exploring staff experience of an "enriched environment" within stroke rehabilitation: a qualitative sub-study.', Disabil Rehabil, 36 1783-1789 (2014) [C1] | ||
| 2014 | Bivard A, Krishnamurthy V, Stanwell P, Yassi N, Spratt NJ, Nilsson M, et al., 'Spectroscopy of reperfused tissue after stroke reveals heightened metabolism in patients with good clinical outcomes', JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 34 1944-1950 (2014) [C1] DOI: 10.1038/jcbfm.2014.166 | Author URL Co-authors: CHRIS LEVI, PETER STANWELL, mark parsons | ||
| 2014 | Janssen H, Ada L, Bernhardt J, McElduff P, Pollack M, Nilsson M, Spratt NJ, 'An enriched environment increases activity in stroke patients undergoing rehabilitation in a mixed rehabilitation unit: a pilot non-randomized controlled trial', DISABILITY AND REHABILITATION, 36 255-262 (2014) [C1] | ||
| 2014 | Murtha LA, Mcleod DD, Mccann SK, Pepperall D, Chung S, Levi CR, et al., 'Short-duration hypothermia after ischemic stroke prevents delayed intracranial pressure rise', International Journal of Stroke, 9 553-559 (2014) [C1] DOI: 10.1111/ijs.12181 Co-authors: CHRIS LEVI, DAMIAN MCLEOD | ||
| 2014 | Janssen H, Ada L, Bernhardt J, McElduff P, Pollack M, Nilsson M, Spratt N, 'Physical, cognitive and social activity levels of stroke patients undergoing rehabilitation within a mixed rehabilitation unit', Clinical Rehabilitation, 28 91-101 (2014) [C1] | ||
| 2014 | Bivard A, Krishnamurthy V, Stanwell P, Levi C, Spratt NJ, Davis S, Parsons M, 'Arterial Spin Labeling Versus Bolus-Tracking Perfusion in Hyperacute Stroke', Stroke, 45 127-133 (2014) [C1] DOI: 10.1161/STROKEAHA.113.003218 | Author URL Co-authors: CHRIS LEVI, PETER STANWELL, mark parsons | ||
| 2014 | Murtha LA, McLeod DD, Pepperall D, McCann SK, Beard DJ, Tomkins AJ, et al., 'Intracranial pressure elevation after ischemic stroke in rats: cerebral edema is not the only cause, and short-duration mild hypothermia is a highly effective preventive therapy.', J Cereb Blood Flow Metab, (2014) DOI: 10.1038/jcbfm.2014.230 | Author URL Co-authors: DAMIAN MCLEOD | ||
| 2014 | Bhaskar S, Evans M, Kitsos G, Russel M, Stanwell P, Walker R, et al., 'The influence of initial stroke severity on the likelihood of death at 90 days following acute stroke: A tertiary hospital stroke register study', INTERNATIONAL JOURNAL OF STROKE, 9 5-5 (2014) Co-authors: PETER STANWELL | ||
| 2013 | McLeod DD, Beard DJ, Parsons MW, Levi CR, Calford MB, Spratt NJ, 'Inadvertent Occlusion of the Anterior Choroidal Artery Explains Infarct Variability in the Middle Cerebral Artery Thread Occlusion Stroke Model', PLOS ONE, 8 (2013) [C1] DOI: 10.1371/journal.pone.0075779 | Author URL Co-authors: CHRIS LEVI, DAMIAN MCLEOD, mark parsons | ||
| 2013 | Magin P, Lasserson D, Parsons M, Spratt N, Evans M, Russell M, et al., 'Referral and triage of patients with transient ischemic attacks to an acute access clinic: Risk stratification in an Australian setting', International Journal of Stroke, 8 81-89 (2013) [C1] DOI: 10.1111/ijs.12014 Co-authors: CHRIS LEVI, Parker magin, mark parsons | ||
| 2013 | Menon BK, O'Brien B, Bivard A, Spratt NJ, Demchuk AM, Miteff F, et al., 'Assessment of leptomeningeal collaterals using dynamic CT angiography in patients with acute ischemic stroke', Journal of Cerebral Blood Flow and Metabolism, 33 365-371 (2013) [C1] Co-authors: CHRIS LEVI, mark parsons | ||
| 2013 | Bivard A, Levi C, Spratt N, Parsons M, 'Perfusion CT in Acute Stroke: A Comprehensive Analysis of Infarct and Penumbra', RADIOLOGY, 267 543-550 (2013) [C1] DOI: 10.1148/radiol.12120971 | Author URL Co-authors: CHRIS LEVI, mark parsons | ||
| 2013 | Marsden DL, Dunn A, Callister R, Levi CR, Spratt NJ, 'Characteristics of Exercise Training Interventions to Improve Cardiorespiratory Fitness After Stroke: A Systematic Review With Meta-analysis', NEUROREHABILITATION AND NEURAL REPAIR, 27 775-788 (2013) [C1] DOI: 10.1177/1545968313496329 | Author URL Co-authors: CHRIS LEVI, ROBIN CALLISTER | ||
| 2013 | Janssen H, Speare S, Spratt NJ, Sena ES, Ada L, Hannan AJ, et al., 'Exploring the Efficacy of Constraint in Animal Models of Stroke: Meta-analysis and Systematic Review of the Current Evidence', NEUROREHABILITATION AND NEURAL REPAIR, 27 3-12 (2013) [C1] | ||
| 2013 | Zareie H, Quain DA, Parsons M, Inder KJ, McElduff P, Miteff F, et al., 'The influence of anterior cerebral artery flow diversion measured by transcranial Doppler on acute infarct volume and clinical outcome in anterior circulation stroke', INTERNATIONAL JOURNAL OF STROKE, 8 228-234 (2013) [C1] DOI: 10.1111/j.1747-4949.2012.00801.x | Author URL Co-authors: CHRIS LEVI, KERRY INDER, mark parsons | ||
| 2013 | Meretoja A, Davis SM, Campbell BCV, Yassi N, Yan B, Churilov L, et al., 'The Spot sign and Tranexamic acid On Preventing ICH growth - AUStralasia Trial (STOP-AUST): Protocol of a phase II randomized, placebo-controlled, double-blind, multicenter trial', International Journal of Stroke, (2013) [C3] DOI: 10.1111/ijs.12132 Co-authors: CHRIS LEVI, mark parsons | ||
| 2013 | Mcleod DD, Parsons MW, Hood R, Hiles B, Allen J, Mccann SK, et al., 'Perfusion computed tomography thresholds defining ischemic penumbra and infarct core: Studies in a rat stroke model', International Journal of Stroke, (2013) DOI: 10.1111/ijs.12147 Co-authors: CHRIS LEVI, DAMIAN MCLEOD, mark parsons | ||
| 2012 | Parsons MW, Spratt NJ, Bivard A, Campbell B, Chung K, Miteff F, et al., 'A randomized trial of tenecteplase versus alteplase for acute ischemic stroke', New England Journal of Medicine, 366 1099-1107 (2012) [C1] Co-authors: CHRIS LEVI, mark parsons | ||
| 2012 | Skelding KA, Spratt NJ, Fluechter L, Dickson PW, Rostas JA, 'alpha CaMKII is differentially regulated in brain regions that exhibit differing sensitivities to ischemia and excitotoxicity', Journal of Cerebral Blood Flow and Metabolism, 32 2181-2192 (2012) [C1] Co-authors: JOHN ROSTAS, KATHRYN SKELDING, PHIL DICKSON | ||
| 2012 | Janssen H, Ada L, Karayanidis F, Drysdale K, McElduff P, Pollack MR, et al., 'Translating the use of an enriched environment poststroke from bench to bedside: study design and protocol used to test the feasibility of environmental enrichment on stroke patients in rehabilitation', International Journal of Stroke, 7 521-526 (2012) [C3] Co-authors: FRINI KARAYANIDIS, KAREN DRYSDALE | ||
| 2011 | Spratt NJ, Donnan GA, McLeod DD, Howells DW, ''Salvaged' stroke ischaemic penumbra shows significant injury: Studies with the hypoxia tracer FMISO', Journal of Cerebral Blood Flow and Metabolism, 31 934-943 (2011) [C1] Co-authors: DAMIAN MCLEOD | ||
| 2011 | Bivard A, Spratt NJ, Levi CR, Parsons MW, 'Acute stroke thrombolysis: Time to dispense with the clock and move to tissue-based decision making?', Expert Review of Cardiovascular Therapy, 9 451-461 (2011) [C1] Co-authors: CHRIS LEVI, mark parsons | ||
| 2011 | McLeod DD, Parsons MW, Levi CR, Beautement S, Buxton D, Roworth B, Spratt NJ, 'Establishing a rodent stroke perfusion computed tomography model', International Journal of Stroke, 6 284-289 (2011) [C1] DOI: 10.1111/j.1747-4949.2010.00564.x Co-authors: CHRIS LEVI, DAMIAN MCLEOD, mark parsons | ||
| 2011 | Bivard A, Spratt NJ, Levi CR, Parsons MW, 'Perfusion computer tomography: Imaging and clinical validation in acute ischaemic stroke', Brain, 134 3408-3416 (2011) [C1] Co-authors: CHRIS LEVI, mark parsons | ||
| 2011 | Parsons MW, Bivard A, McElduff P, Spratt NJ, Levi CR, 'Defining the extent of irreversible brain ischemia using perfusion computed tomography', Cerebrovascular Diseases, 31 238-245 (2011) [C1] DOI: 10.1159/000321897 Co-authors: CHRIS LEVI, mark parsons | ||
| 2010 | Marsden DL, Spratt NJ, Walker R, Barker DJ, Attia JR, Pollack MR, et al., 'Trends in stroke attack rates and case fatality in the Hunter Region, Australia 1996-2008', Cerebrovascular Diseases, 30 500-507 (2010) [C1] DOI: 10.1159/000319022 Co-authors: CHRIS LEVI, JOHN ATTIA, mark parsons | ||
| 2010 | Garnett AR, Marsden DL, Parsons MW, Quain DA, Spratt NJ, Loudfoot AR, et al., 'The rural Prehospital Acute Stroke Triage (PAST) trial protocol: A controlled trial for rapid facilitated transport of rural acute stroke patients to a regional stroke centre', International Journal of Stroke, 5 506-513 (2010) [C1] DOI: 10.1111/j.1747-4949.2010.00522.x Co-authors: CHRIS LEVI, mark parsons | ||
| 2010 | Janssen H, Bernhardt J, Collier JM, Sena ES, McElduff P, Attia JR, et al., 'An enriched environment improves sensorimotor function post-ischemic stroke', Neurorehabilitation and Neural Repair, 24 802-813 (2010) [C1] Co-authors: JOHN ATTIA | ||
| 2010 | Abed H, Barlow MA, Wellings TP, Spratt NJ, Collins N, 'Cardiogenic shock complicating subarachnoid haemorrhage diagnosed as Tako Tsubo Cardiomyopathy: A cautionary tale', Heart Lung and Circulation, 19 476-479 (2010) [C3] | ||
| 2009 | Levi CR, Bateman GA, Spratt NJ, McElduff P, Parsons MW, Miteff F, 'The independent predictive utility of computed tomography angiographic collateral status in acute ischaemic stroke', Brain, 132 2231-2238 (2009) [C1] DOI: 10.1093/brain/awp155 Co-authors: CHRIS LEVI, mark parsons | ||
| 2009 | Parsons MW, Miteff F, Bateman GA, Spratt NJ, Loiselle A, Attia JR, Levi CR, 'Acute ischemic stroke imaging-guided tenecteplase treatment in an extended time window', Neurology, 72 915-921 (2009) [C1] DOI: 10.1212/01.wnl.0000344168.05315.9d Co-authors: CHRIS LEVI, JOHN ATTIA, mark parsons | ||
| 2008 | Quain DA, Parsons MW, Loudfoot AR, Spratt NJ, Evans MK, Russell ML, et al., 'Improving access to acute stroke therapies: A controlled trial of organised pre-hospital and emergency care', Medical Journal of Australia, 189 429-433 (2008) [C1] Co-authors: CHRIS LEVI, JOHN ATTIA, mark parsons | ||
| Show 46 more | |||
Review (1 outputs)
| Year | Citation | Altmetrics | Link |
|---|---|---|---|
| 2003 | Spratt N, Howells DW, 'Ischaemic tolerance and mitochondrial uncoupling - can we learn from the cell', Cerebrovascular Diseases (2003) [C1] DOI: 10.1159/000083878 |
Conference (78 outputs)
| Year | Citation | Altmetrics | Link |
|---|---|---|---|
| 2014 | Marsden D, Dunn A, Callister R, McElduff P, Levi CR, Spratt NJ, 'Can independently ambulant stroke survivors exercise for thirty minutes at a moderate intensity? An observational study', INTERNATIONAL JOURNAL OF STROKE (2014) [E3] Co-authors: CHRIS LEVI, ROBIN CALLISTER | ||
| 2014 | Dunn A, Marsden D, Van Vliet P, Spratt NJ, Callister R, 'How do the shuttle walk test and 6-minute walk test compare as measures of cardiorespiratory fitness in stroke survivors?', INTERNATIONAL JOURNAL OF STROKE (2014) [E3] Co-authors: PAULETTE VANVLIET, ROBIN CALLISTER | ||
| 2014 | Zareie H, Selmes C, Kawano H, Parsons M, Spratt N, Miteff F, et al., 'Feasibility and accuracy of fusion TCCD in acute stroke treatment', INTERNATIONAL JOURNAL OF STROKE (2014) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2014 | Zareie H, Selmes C, Kawano H, Parsons M, Spratt N, Miteff F, et al., 'Feasibility and accuracy of fusion TCCD in monitoring acute stroke treatment', INTERNATIONAL JOURNAL OF STROKE (2014) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2014 | Bivard A, Krishnamurthy V, Levi C, McElduff P, Miteff F, Spratt N, et al., 'Better stroke outcomes despite worse baseline stroke severity - The value of a combined clinical and advanced CT selection approach to thrombolysis', INTERNATIONAL JOURNAL OF STROKE (2014) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2014 | Bivard A, Krishnamurthy V, Levi C, McElduff P, Miteff F, Spratt N, et al., 'Does the presence of CTP mismatch predict better outcomes in thrombolysis-treated patients?', INTERNATIONAL JOURNAL OF STROKE (2014) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2014 | Marsden D, Dunn A, Callister R, McElduff P, Levi C, Spratt N, 'Cardiorespiratory fitness testing and training in stroke survivors: A comparison of peak oxygen consumption results from the upright cycle test, six minute walk test and circuit exercise stations', INTERNATIONAL JOURNAL OF STROKE (2014) [E3] Co-authors: CHRIS LEVI, ROBIN CALLISTER | ||
| 2014 | Bivard A, Krishnamurthy V, Levi C, Mcelduff P, Miteff F, Spratt N, et al., 'Stroke Thrombolysis: Tissue Is More Important Than Time', CEREBROVASCULAR DISEASES (2014) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2014 | Bivard A, Krishnamurthy V, Levi C, Mcelduff P, Miteff F, Spratt N, et al., 'Better Stroke Outcomes Despite Worse Baseline Stroke Severity with Combined Clinical and CTP Assessment', CEREBROVASCULAR DISEASES (2014) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2014 | Bivard A, Krishnamurthy V, Levi C, McElduff P, Miteff F, Spratt N, et al., 'Stroke thrombolysis: Tissue is more important than time', INTERNATIONAL JOURNAL OF STROKE (2014) | ||
| 2013 | Callister R, Dunn A, Marsden DL, Spratt NJ, Van Vliet P, 'How has the 6 minute walk test been used in the stroke population? A Systematic Review with meta-analysis', International Journal of Stroke, Brisbane (2013) [E3] DOI: 10.1111/ijs.12172 Co-authors: PAULETTE VANVLIET | ||
| 2013 | Schleicher N, Tomkins AJ, Kampschulte M, Yan F, Hyvelin J-M, Juenemann M, et al., 'Efficacy of the novel therapeutic microbubble preparation BR38 in sonothrombolysis (ST) of acute cerebral small artery occlusion', CEREBROVASCULAR DISEASES (2013) [E3] | ||
| 2013 | Bivard A, Stanwell P, Spratt N, Levi C, Krishnamurthy V, Davis S, Parsons M, 'Arterial spin labelling versus bolus-tracking CT and MR in hyper-acute ischemic stroke', CEREBROVASCULAR DISEASES (2013) [E3] Co-authors: CHRIS LEVI, PETER STANWELL, mark parsons | ||
| 2013 | Beard D, McLeod D, Spratt N, 'The collateral circulation: key to outcome in mice and men', INTERNATIONAL JOURNAL OF STROKE (2013) [E3] Co-authors: DAMIAN MCLEOD | ||
| 2013 | Marsden DL, Dunn A, Callister R, Levi CR, Spratt NJ, 'Exercise training interventions that are aerobic or include an aerobic component can improve cardiorespiratory fitness after stroke: a systematic review with meta-analysis', CEREBROVASCULAR DISEASES (2013) [E3] Co-authors: CHRIS LEVI, ROBIN CALLISTER | ||
| 2013 | Janssen H, Speare S, Spratt NJ, Sena ES, Ada L, Hannan AJ, et al., 'Exploring the efficacy of constraint in animal models of stroke: meta-analysis and systematic review of the current evidence', INTERNATIONAL JOURNAL OF STROKE (2013) [E3] | ||
| 2013 | Dunn A, Marsden DL, Spratt NJ, Van Vliet P, Callister R, 'How has the 6 minute walk test been used in the stroke population? A Systematic Review with meta-analysis', INTERNATIONAL JOURNAL OF STROKE (2013) [E3] Co-authors: PAULETTE VANVLIET, ROBIN CALLISTER | ||
| 2013 | Marsden DL, Dunn A, Callister R, Levi CR, Spratt NJ, 'Improving cardiorespiratory fitness after stroke by using exercise interventions that are aerobic or include an aerobic component: A systematic review with meta-analysis', INTERNATIONAL JOURNAL OF STROKE (2013) [E3] Co-authors: CHRIS LEVI, ROBIN CALLISTER | ||
| 2013 | Egan KJ, Janssen H, Sena ES, Bernhardt J, Longley L, Speare S, et al., 'Exercise reduces infarct volume and facilitates neurobehavioural recovery: systematic review and meta-analysis of exercise in animal models of stroke', INTERNATIONAL JOURNAL OF STROKE (2013) [E3] | ||
| 2013 | Lillicrap T, Stanwell P, Neeman T, Parsons M, Spratt N, Levi CR, Lueck C, 'Variation in regional brain temperature as measured by MR thermography in healthy volunteers', INTERNATIONAL JOURNAL OF STROKE (2013) [E3] Co-authors: CHRIS LEVI, PETER STANWELL, mark parsons | ||
| 2013 | Tomkins AJ, Schleicher N, Nedelmann M, Spratt NJ, 'PLATELET RICH CLOTS ARE RESISTANT TO LYSIS BY THROMBOLYTIC THERAPY IN A RAT MODEL OF EMBOLIC STROKE', CEREBROVASCULAR DISEASES (2013) [E3] | ||
| 2013 | Marsden DL, Dunn A, Callister R, Levi CR, Spratt NJ, 'Interventions to improve cardiorespiratory fitness after stroke: a systematic review with meta-analysis', INTERNATIONAL JOURNAL OF STROKE (2013) [E3] Co-authors: CHRIS LEVI, ROBIN CALLISTER | ||
| 2012 | Janssen H, Ada L, Bernhardt J, Karayanidis F, Drysdale K, McElduff P, et al., 'The use of an enriched environment post stroke: Translating from bench to bedside', Neurorehabilitation & Neural Repair: WCNR 2012 Oral Abstracts, Melbourne, VIC (2012) [E3] Co-authors: FRINI KARAYANIDIS, KAREN DRYSDALE | ||
| 2012 | Rostas JA, Skelding KA, Fluechter L, Dickson PW, Spratt NJ, 'CaMKII is differentially regulated in striatum and cortex', Journal of Molecular Neuroscience: Abstracts The 21st Annual Meeting of the Israel Society for Neuroscience & The First Binational Australian-Israeli Meeting in Neuroscience, Eilat, Israel (2012) [E3] Co-authors: JOHN ROSTAS, KATHRYN SKELDING, PHIL DICKSON | ||
| 2012 | Marsden DL, Garnett AR, Parsons MW, Spratt NJ, Watson T, Loudfoot A, et al., 'No thrombolysis service? No worries. A controlled trial of facilitated access for rural stroke patients to a regional thrombolysis centre - The Hunter Rural PAST Protocol', Abstract E-book. 2012 European Stroke Conference, Lisbon, Portugal (2012) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2012 | Marsden DL, Callister R, Dunn A, Levi CR, Spratt NJ, 'How fit is the stroke survivor? Assessing the fitness levels of stroke survivors by comparing four methods available in the clinical setting. The 'HowFITSS' Trial', Abstract E-book. 2012 European Stroke Conference, Lisbon, Portugal (2012) [E3] Co-authors: CHRIS LEVI, ROBIN CALLISTER | ||
| 2012 | Bernhardt J, Janssen H, Ada L, McElduff P, Pollack M, Spratt NJ, 'Exposure to an enriched environment increases post stroke activity and decreases time spent alone', Abstract E-book. 2012 European Stroke Conference, Lisbon, Portugal (2012) [E3] | ||
| 2012 | Arulampalam A, McLeod DD, Spratt NJ, 'Fluid shifts in the rat brain after ischaemic stroke', Abstracts. Australian Neuroscience Society 32nd Annual Meeting, Gold Coast, Queensland (2012) [E3] Co-authors: DAMIAN MCLEOD | ||
| 2012 | Murtha LA, McLeod DD, Spratt NJ, 'The effects of therapeutic hypothermia on intracranial pressure after experimental ischemic stroke', Abstracts. Australian Neuroscience Society 32nd Annual Meeting, Gold Coast, Queensland (2012) [E3] Co-authors: DAMIAN MCLEOD | ||
| 2012 | Skelding KA, Abdul Majeed ABB, Dickson PW, Spratt NJ, Rostas JA, 'CAMKII is regulated differently in brains regions with differing sensitivities to ischaemia/excitotoxicity', Abstracts. Australian Neuroscience Society 32nd Annual Meeting, Gold Coast, Queensland (2012) [E3] Co-authors: JOHN ROSTAS, KATHRYN SKELDING, PHIL DICKSON | ||
| 2012 | McLeod DD, Beard DJ, Imtiaz MS, Spratt NJ, 'Validating a novel method for measuring leptomeningeal collateral flow in experimental stroke', The Stroke Interventionalist, Los Angeles, CA (2012) [E3] Co-authors: DAMIAN MCLEOD | ||
| 2012 | Beard DJ, McLeod DD, Imtiaz MS, Spratt NJ, 'Quantitative assessment of leptomeningeal collateral flow in experimental stroke', The Stroke Interventionalist, Los Angeles, CA (2012) [E3] Co-authors: DAMIAN MCLEOD | ||
| 2012 | Garnett AR, Marsden DL, Parsons MW, Spratt NJ, Watson T, Loudfoot AR, et al., 'The Hunter Rural PAST Protocol: An innovative and effective partnership between ambulance and a regional thrombolysis centre to facilitate access for rural stroke patient to thrombolysis', International Journal of Stroke, Darling Harbour, Sydney (2012) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2012 | Alborough K, White JH, Janssen H, Spratt NJ, Jordan L, Pollack MR, 'Exploring staff experience of an 'Enriched Environment' within stroke rehabilitation: A qualitative sub-study', International Journal of Stroke, Darling Harbour, Sydney (2012) [E3] | ||
| 2012 | Bartley E, White JH, Janssen H, Spratt NJ, Pollack M, 'Exploring the experience of stroke rehabilitation following exposure to an enriched environment', International Journal of Stroke, Darling Harbour, Sydney (2012) [E3] | ||
| 2012 | Dunn A, Marsden DL, Spratt NJ, Levi CR, Callister R, 'Does knee strength affect walking speed, distance and fitness levels following stroke? Preliminary results from the 'How Fit is the Stroke Survivor?' (HowFITSS?) trial', International Journal of Stroke, Darling Harbour, Sydney (2012) [E3] Co-authors: CHRIS LEVI, ROBIN CALLISTER | ||
| 2012 | Marsden DL, Dunn A, Callister R, Levi CR, Spratt NJ, 'Assessing stroke survivors' cardiorespiratory fitness - A comparison of four methods available in the clinical setting: Preliminary results from the 'How Fit is the Stroke Survivor?' (HowFITSS?) trial', International Journal of Stroke, Darling Harbour, Sydney (2012) [E3] Co-authors: CHRIS LEVI, ROBIN CALLISTER | ||
| 2012 | Marsden DL, Dunn A, Callister R, Levi CR, Spratt NJ, 'Measuring cardiorespiratory fitness and oxygen consumption after stroke - A Systematic Review', International Journal of Stroke, Darling Harbour, Sydney (2012) [E3] Co-authors: CHRIS LEVI, ROBIN CALLISTER | ||
| 2011 | Shiue I, Marsden DL, Spratt NJ, Matzarakis A, McElduff P, Anderson CS, Levi CR, 'Psychologically equivalent temperature and stroke attack rates', Cerebrovascular Diseases, Hamburg, Germany (2011) [E3] Co-authors: CHRIS LEVI | ||
| 2011 | Menon BK, O'Brien W, Bivard A, Levi CR, Spratt NJ, Parsons MW, 'Anatomic and physiologic assessment of leptomeningeal collaterals in acute ischemic stroke patients using dynamic time resolved 320 slice CT angiography', Stroke, Ottawa, Canada (2011) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2011 | Janssen H, Ada L, Bernhardt J, McElduff P, Pollack MR, Spratt NJ, 'Levels of physical, cognitive and social activity are low and stable during a two week period of stroke rehabilitation', APA Physiotherapy Conference 2011 Abstract Presentations, Brisbane (2011) [E3] | ||
| 2011 | Bivard A, Levi CR, Spratt NJ, Parsons MW, 'Delayed perfusion predicts the volume of the perfusion lesion', Stroke, Los Angeles, CA (2011) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2011 | Tomkins AJ, Chung S, Pepperall D-G, Beard D, Calford MB, Spratt NJ, 'Distribution and quantification of the neurosteroid allopregnanolone in response to stroke', Oral abstracts. Australian Neuroscience Society Annual Meeting, Auckland, NZ (2011) [E3] | ||
| 2011 | Skelding KA, Chung S, Pepperall D-G, Tomkins AJ, Spratt NJ, Rostas JA, 'The role of CaMKII in neuronal sensitivity to ischaemia', Oral abstracts. Australian Neuroscience Society Annual Meeting, Auckland, NZ (2011) [E3] Co-authors: JOHN ROSTAS, KATHRYN SKELDING | ||
| 2011 | Bivard A, Spratt NJ, Levi CR, Parsons MW, 'Perfusion CT predicts subsequent tissue and clinical outcome in hyperacute ischemic stroke', Cerebrovascular Diseases, Hamburg, Germany (2011) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2011 | Russell ML, Evans MK, Royan AT, Magin PJ, Lasserson D, Attia JR, et al., 'Referral and triage of patients with TIAs to an acute access clinic: Risk-stratification performance in an Australian setting', International Journal of Stroke, Adelaide, SA (2011) [E3] Co-authors: CHRIS LEVI, JOHN ATTIA, Parker magin, mark parsons | ||
| 2011 | O'Brien W, Chung K, Levi CR, Spratt NJ, Parsons MW, 'Comparative study of Multimodal Computed Tomography (MdCT) and Magnetic resonance imaging (MRI) in Transient ischaemic attack and minor stroke patient', International Journal of Stroke, Adelaide, SA (2011) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2011 | Murtha LA, McLeod DD, McCann S, Pepperall D-G, Spratt NJ, 'Short duration hypothermia results in sustained prevention of intracranial pressure elevation following experimental stroke', International Journal of Stroke, Adelaide, SA (2011) [E3] Co-authors: DAMIAN MCLEOD | ||
| 2011 | Menon B, O'Brien W, Bivard A, Levi CR, Spratt NJ, Parsons MW, 'Detailed anatomic and physiologic assessment of leptomeningeal collaterals in acute ischemic stroke patients using dynamic time resolved 320 slice CT angiography', International Journal of Stroke, Adelaide, SA (2011) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2011 | Lillicrap T, Jyoti R, Levi CR, Parsons MW, Spratt NJ, Stanwell P, Lueck C, 'Temperature measurements using MR spectroscopy: Validation and calibration in healthy volunteers', International Journal of Stroke, Adelaide, SA (2011) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2011 | Bivard A, Spratt NJ, Levi CR, Parsons MW, 'CTP thresholds to detect acute ischeamic stroke tissue pathophysiology', International Journal of Stroke, Adelaide, SA (2011) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2010 | Skelding KA, Tomkins AJ, Fluechter L, Pepperall D-G, Spratt NJ, Rostas JA, 'Ischaemia-induced CaMKII phosphorylation in hypertensive and normotensive rats', Proceding of the Australian Neuroscience Society, Sydney, NSW (2010) [E3] Co-authors: JOHN ROSTAS, KATHRYN SKELDING | ||
| 2010 | Lillicrap T, Stanwell P, Parsons MW, Spratt NJ, Hudson S, Levi CR, 'MR spectroscopy in brain temperature measurement and application to induced hypothermia therapy', Circulation, Beijing (2010) [E3] Co-authors: CHRIS LEVI, PETER STANWELL, mark parsons | ||
| 2010 | Lillicrap TP, Hudson S, Stanwell P, Parsons MW, Spratt NJ, Levi CR, 'MR spectroscopy and diffusion-weighted MRI can accurately measure both reduced and increased brain temperature', Stroke, San Antonio, Texas (2010) [E3] Co-authors: CHRIS LEVI, PETER STANWELL, mark parsons | ||
| 2010 | Bivard A, McElduff P, Spratt NJ, Levi CR, Parsons MW, 'Validating perfusion-computed tomography in defining extent of irreversible brain ischemia', Circulation, Beijing (2010) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2010 | Bivard A, McElduff P, Levi CR, Spratt NJ, Parsons MW, 'Defining the extent of irreversible brain ischemia using perfusion computed tomography', Stroke, San Antonio, Texas (2010) [E3] Co-authors: CHRIS LEVI, mark parsons | ||
| 2009 | McLeod DD, Parsons MW, Levi CR, Beautement S, Roworth B, Buxton D, et al., 'An experimental model to investigate CT brain perfusion after stroke', ANS 2009 Abstracts: Posters, Canberra, ACT (2009) [E3] Co-authors: CHRIS LEVI, DAMIAN MCLEOD, mark parsons | ||
| 2009 | McLeod DD, Spratt NJ, Levi CR, Beautement S, Roworth B, Buxton D, et al., 'Experimental validation of perfusion computed tomography in acute middle cerebral artery occlusion', ACBRC 2009 Abstracts, Tianjin, China (2009) [E3] Co-authors: CHRIS LEVI, DAMIAN MCLEOD, mark parsons | ||
| 2009 | Tomkins AJ, Rostas JA, Pepperall D-G, Calford MB, Spratt NJ, 'Infarction occurs more rapidly in hypertensive rats', ANS 2009 Abstracts: Posters, Canberra, ACT (2009) [E3] Co-authors: JOHN ROSTAS | ||
| 2009 | McLeod DD, Spratt NJ, Levi CR, Beautement S, Roworth B, Buxton D, et al., 'Perfusion computed tomography for acute stroke: A model for experimental validation', Cerebrovascular Diseases, Stockholm, Sweden (2009) [E3] DOI: 10.1159/000221776 Co-authors: CHRIS LEVI, DAMIAN MCLEOD, mark parsons | ||
| 2008 | Tomkins AJ, Pepperall D-G, Calford MB, Spratt NJ, 'Investigation of the putative neuroprotectant effect of the neurosteroid allopregnanolone after stroke', Internal Medicine Journal, Sydney, NSW (2008) [E3] | ||
| 2008 | Miteff F, Parsons MW, Bateman GA, Spratt NJ, Levi CR, 'Does collateral vessel status on CT angiography add to perfusion CT in the prediction of outcome after acute ischaemc stroke?', Internal Medicine Journal, Sydney, NSW (2008) [E3] DOI: 10.1111/j.1445-5994.2008.01755_7.x Co-authors: CHRIS LEVI, mark parsons | ||
| 2008 | Spratt NJ, 'Locating the target, and identifying mechanisms and therapies for neuroprotection in stroke', Journal of Neurochemistry, Shanghai, China (2008) [E3] | ||
| 2008 | Janssen H, Collier J, Bernhardt J, Pollack MR, Sena E, Spratt NJ, 'Gathering the evidence: The use of an enriched environment post stroke', Internal Medicine Journal, Sydney, NSW (2008) [E3] | ||
| 2008 | Pepperall D-G, Tomkins AJ, Calford MB, Spratt NJ, 'The effectiveness of neurological tests of somatosensory function following stroke in rats', Internal Medicine Journal, Sydney, NSW (2008) [E3] | ||
| Show 75 more | |||
Other (1 outputs)
| Year | Citation | Altmetrics | Link |
|---|---|---|---|
| 2010 | Spratt NJ, 'Where next for stroke?', ( issue.7 pp.660): The Lancet Publishing Group (2010) [C3] |
Edit
- Indicates that the researcher may be seeking students for this project.Characterising a newly identified mechanism causing elevation of intracranial pressure after acute neurological injury$494,400
Altering the Rehabililtation Environment to Improve Stroke Survivor Activity (AREISSA): A Phase II Trial.$264,242
Determining factors within cerebrospinal fluid that influence intracranial pressure post-stroke$35,000
Improving Fitness, Function, Fatigue and Feelings through physcial Fun: a pilot trial for stroke survivors $20,000
Tablets and Technology During Stroke Recovery (TNT)$19,924
Cooling the brain via the skin to prevent intracranial pressure elevation after stroke$19,275
Effects of intracranial pressure on collateral blood flow after stroke: a new pathophysiological mechanism and potential therapy
$10,000
Quantifying Physical, Cognitive and Social Activity Early After Stroke$3,000
2013 Vice Chancellor's Award for Supervision Excellence$2,000
Greater Charitable Foundation Fellows in Stroke Research$100,000
Enriched Environment in Rehabilitation - A Phase II Trial$70,000
Novel mechanisms of ‘Stroke-in-Progression’: Intracranial pressure elevation and collateral blood vessel failure after minor stroke$20,000
Introduction to research and scientific methods$2,000
An international comparison of systems of care, risk stratification and outcomes in TIA and minor stroke$1,149,593
Short duration hypothermia to prevent subsequent intracranial pressure rise.$429,453
A new paradigm to prevent intracranial hypertension$391,076
Experimental brain imaging to investigate novel protective mechanisms of short duration body cooling after stroke$20,000
Role of CaMKII targeting in neuronal susceptibility to excitotoxic cell death$20,000
Telemetry measurement of Intracranial Pressure in Stroke and Hypothermia$15,000
Fitness Training In Stroke Trial (FiTIST): a randomised controlled assessor blind multicentre cross-over trial$85,600
Role of CaMKII targeting in stroke susceptibility and outcome$18,200
Role of CaMKII targeting in stroke susceptibility and outcome$15,000
HMRI PhD Scholarship Travel Grant, Sponsored by Jennie Thomas$10,000
The effect of stroke on cranial compartment volumes and intracranial pressure$2,600
Testing stroke sonothrombolysis using an improved experimental model of thromboembolic stroke$81,386
Improving patient selection for acute stroke therapies - an experimental model of CT brain perfusion after stroke$50,000
Environmental enrichment post stroke$46,848
The use of an enriched environment to improve recovery after stroke$20,000
Effects of therapeutic hypothermia and rewarming on intracranial pressure in experimental stroke$2,064
Improving Patient Slection of rHighley Effective Stroke Therapy$240,000
China-Australia therapeutic hypothermia in stroke (CATHS) research program: identification of diagnostic molecular markers and therapeutic targets involved in re-warming related brain injury$230,275
Establishing Computed Tomography Perfusion (CTP) imaging in an animal stroke model$20,000
Towards better early imaging in stroke: Use of an experimental model to investigate CT brain perfusion$13,000
A randomised controlled trial of mild hypothermia in acute ischaemic stroke$117,176
Is CaMKII autophosphorylation a mechanism of endogenous neuroprotection after stroke?$14,417
Hypoxic culture chamber and low-pressure gas regulators$11,500
Translation of novel neuroprotection and stroke recovery strategies from the laboratory to the clinic$171,750
Translation of novel neuroprotection and stroke recovery strategies from laboratory to the clinic$60,000
Foundation for High Blood Pressure award.$60,000
Grants and Funding
Summary
| Number of grants | 39 |
|---|---|
| Total funding | $4,354,779 |
Click on a grant title below to expand the full details for that specific grant.
2015 (1 grants)
Characterising a newly identified mechanism causing elevation of intracranial pressure after acute neurological injury$494,400
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt, Doctor Mark Baker | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $494,400 | 2015 | 2017 |
| GNo:G1400231 | ||
2014 (8 grants)
Altering the Rehabililtation Environment to Improve Stroke Survivor Activity (AREISSA): A Phase II Trial.$264,242
Funding Body: National Heart Foundation of Australia
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt, Associate Professor Louise Ada, Professor Michael Nilsson, Professor Sandy Middleton, Associate Professor Julie Bernhardt, Professor Leonid Churilov, Conjoint Professor Chris Levi, Conjoint Associate Professor Michael Pollack, Associate Professor Steven Faux, Professor Lin Perry, Dr Annie McCluskey | ||
| Scheme | Role | |
| NSW Cardiovascular Research Network Research Development Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $264,242 | 2014 | 2015 |
| GNo:G1301044 | ||
Determining factors within cerebrospinal fluid that influence intracranial pressure post-stroke$35,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Miss Rebecca Hood, Doctor Neil Spratt | ||
| Scheme | Role | |
| Postgraduate Research Scholarship | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $35,000 | 2014 | 2015 |
| GNo:G1401409 | ||
Improving Fitness, Function, Fatigue and Feelings through physcial Fun: a pilot trial for stroke survivors $20,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt, Professor Robin Callister | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $20,000 | 2014 | 2014 |
| GNo:G1400143 | ||
Tablets and Technology During Stroke Recovery (TNT)$19,924
Funding Body: National Stroke Foundation
| Project Team | ||
|---|---|---|
| Ms Heidi Janssen, Doctor Neil Spratt, Ms Louise-Anne Jordan, Doctor Patrick McElduff | ||
| Scheme | Role | |
| Research Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $19,924 | 2014 | 2014 |
| GNo:G1301138 | ||
Cooling the brain via the skin to prevent intracranial pressure elevation after stroke$19,275
Funding Body: National Stroke Foundation
| Project Team | ||
|---|---|---|
| Doctor Damian McLeod, Doctor Neil Spratt | ||
| Scheme | Role | |
| Research Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $19,275 | 2014 | 2014 |
| GNo:G1301145 | ||
Effects of intracranial pressure on collateral blood flow after stroke: a new pathophysiological mechanism and potential therapy
$10,000
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt | ||
| Scheme | Role | |
| Near Miss Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $10,000 | 2014 | 2014 |
| GNo:G1301407 | ||
Quantifying Physical, Cognitive and Social Activity Early After Stroke$3,000
Funding Body: National Stroke Foundation
| Project Team | ||
|---|---|---|
| Mrs Jodie Marquez, Ms Heidi Janssen, Miss Hannah Smith, Doctor Neil Spratt, Doctor Patrick McElduff, Associate Professor Louise Ada | ||
| Scheme | Role | |
| Honours Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $3,000 | 2014 | 2014 |
| GNo:G1301144 | ||
2013 Vice Chancellor's Award for Supervision Excellence$2,000
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt | ||
| Scheme | Role | |
| Award for Supervision Excellence | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $2,000 | 2014 | 2014 |
| GNo:G1400151 | ||
2013 (4 grants)
Greater Charitable Foundation Fellows in Stroke Research$100,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt, Professor Mark Parsons, Conjoint Professor Chris Levi | ||
| Scheme | Role | |
| Stroke Research Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $100,000 | 2013 | 2013 |
| GNo:G1300508 | ||
Enriched Environment in Rehabilitation - A Phase II Trial$70,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Ms Heidi Janssen, Doctor Neil Spratt, Professor Michael Nilsson | ||
| Scheme | Role | |
| Project Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $70,000 | 2013 | 2014 |
| GNo:G1300569 | ||
Novel mechanisms of ‘Stroke-in-Progression’: Intracranial pressure elevation and collateral blood vessel failure after minor stroke$20,000
Funding Body: National Stroke Foundation
| Project Team | ||
|---|---|---|
| Doctor Damian McLeod, Doctor Neil Spratt | ||
| Scheme | Role | |
| Research Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $20,000 | 2013 | 2013 |
| GNo:G1201084 | ||
Introduction to research and scientific methods$2,000
Funding Body: University of Gothenburg
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt | ||
| Scheme | Role | |
| Masters Thesis Project | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $2,000 | 2013 | 2013 |
| GNo:G1201262 | ||
2012 (6 grants)
An international comparison of systems of care, risk stratification and outcomes in TIA and minor stroke$1,149,593
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Conjoint Professor Chris Levi, Conjoint Professor Parker Magin, Dr Daniel Lasserson, Dr Jose Valderas, Associate Professor Helen Dewey, Professor Peter Barber, Professor Peter Rothwell, Doctor Neil Spratt, Dr Dominique Cadilhac, Professor Valery Feigin | ||
| Scheme | Role | |
| Project Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $1,149,593 | 2012 | 2016 |
| GNo:G1100258 | ||
Short duration hypothermia to prevent subsequent intracranial pressure rise.$429,453
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $429,453 | 2012 | 2014 |
| GNo:G1100422 | ||
A new paradigm to prevent intracranial hypertension$391,076
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt | ||
| Scheme | Role | |
| Career Development Fellowships | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $391,076 | 2012 | 2015 |
| GNo:G1100407 | ||
Experimental brain imaging to investigate novel protective mechanisms of short duration body cooling after stroke$20,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Doctor Damian McLeod, Doctor Neil Spratt, Professor Mark Parsons, Conjoint Professor Chris Levi | ||
| Scheme | Role | |
| Project Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $20,000 | 2012 | 2012 |
| GNo:G1101116 | ||
Role of CaMKII targeting in neuronal susceptibility to excitotoxic cell death$20,000
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Emeritus Professor John Rostas, Doctor Neil Spratt, Associate Professor Phillip Dickson, Doctor Nikki Verrills | ||
| Scheme | Role | |
| Near Miss Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $20,000 | 2012 | 2012 |
| GNo:G1200673 | ||
Telemetry measurement of Intracranial Pressure in Stroke and Hypothermia$15,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $15,000 | 2012 | 2012 |
| GNo:G1201131 | ||
2011 (5 grants)
Fitness Training In Stroke Trial (FiTIST): a randomised controlled assessor blind multicentre cross-over trial$85,600
Funding Body: National Heart Foundation of Australia
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt, Conjoint Professor Chris Levi, Professor Robin Callister | ||
| Scheme | Role | |
| Postgraduate Biomedical Research Scholarship | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $85,600 | 2011 | 2014 |
| GNo:G1000862 | ||
Role of CaMKII targeting in stroke susceptibility and outcome$18,200
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Emeritus Professor John Rostas, Doctor Neil Spratt, Doctor Kathryn Skelding | ||
| Scheme | Role | |
| Stroke Research Project Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $18,200 | 2011 | 2011 |
| GNo:G1001013 | ||
Role of CaMKII targeting in stroke susceptibility and outcome$15,000
Funding Body: Brain Foundation (NSW Branch)
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt, Emeritus Professor John Rostas | ||
| Scheme | Role | |
| Research Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $15,000 | 2011 | 2011 |
| GNo:G1000716 | ||
HMRI PhD Scholarship Travel Grant, Sponsored by Jennie Thomas$10,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt | ||
| Scheme | Role | |
| Research Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $10,000 | 2011 | 2011 |
| GNo:G1100898 | ||
The effect of stroke on cranial compartment volumes and intracranial pressure$2,600
Funding Body: National Stroke Foundation
| Project Team | ||
|---|---|---|
| Doctor Damian McLeod, Doctor Neil Spratt | ||
| Scheme | Role | |
| Research Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $2,600 | 2011 | 2011 |
| GNo:G1100727 | ||
2010 (5 grants)
Testing stroke sonothrombolysis using an improved experimental model of thromboembolic stroke$81,386
Funding Body: National Stroke Foundation
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt, Conjoint Professor Chris Levi | ||
| Scheme | Role | |
| Postgraduate Biomedical Scholarship | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $81,386 | 2010 | 2013 |
| GNo:G0190597 | ||
Improving patient selection for acute stroke therapies - an experimental model of CT brain perfusion after stroke$50,000
Funding Body: BellBerry Limited
| Project Team | ||
|---|---|---|
| Professor Mark Parsons, Doctor Neil Spratt, Conjoint Professor Chris Levi, Doctor Damian McLeod, Dr Peter Stanwell | ||
| Scheme | Role | |
| Near Miss | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $50,000 | 2010 | 2012 |
| GNo:G0900222 | ||
Environmental enrichment post stroke$46,848
Funding Body: National Stroke Foundation
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt | ||
| Scheme | Role | |
| Research Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $46,848 | 2010 | 2012 |
| GNo:G1000541 | ||
The use of an enriched environment to improve recovery after stroke$20,000
Funding Body: National Stroke Foundation
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt | ||
| Scheme | Role | |
| Research Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $20,000 | 2010 | 2010 |
| GNo:G1000381 | ||
Effects of therapeutic hypothermia and rewarming on intracranial pressure in experimental stroke$2,064
Funding Body: National Stroke Foundation
| Project Team | ||
|---|---|---|
| Doctor Damian McLeod, Doctor Neil Spratt, Professor Mike Calford | ||
| Scheme | Role | |
| Honours Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $2,064 | 2010 | 2010 |
| GNo:G1000608 | ||
2009 (4 grants)
Improving Patient Slection of rHighley Effective Stroke Therapy$240,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $240,000 | 2009 | 2012 |
| GNo:G0190535 | ||
China-Australia therapeutic hypothermia in stroke (CATHS) research program: identification of diagnostic molecular markers and therapeutic targets involved in re-warming related brain injury$230,275
Funding Body: NSW Office for Science & Medical Research
| Project Team | ||
|---|---|---|
| Conjoint Professor Chris Levi, Doctor Mark Baker, Doctor Neil Spratt, Emeritus Professor John Rostas | ||
| Scheme | Role | |
| China-NSW Collaborative Research Program | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $230,275 | 2009 | 2009 |
| GNo:G0190392 | ||
Establishing Computed Tomography Perfusion (CTP) imaging in an animal stroke model$20,000
Funding Body: National Stroke Foundation
| Project Team | ||
|---|---|---|
| Doctor Damian McLeod, Doctor Neil Spratt, Professor Mike Calford, Conjoint Professor Chris Levi, Professor Mark Parsons | ||
| Scheme | Role | |
| Research Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $20,000 | 2009 | 2009 |
| GNo:G0189942 | ||
Towards better early imaging in stroke: Use of an experimental model to investigate CT brain perfusion$13,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt, Professor Mark Parsons, Doctor Damian McLeod, Conjoint Professor Chris Levi | ||
| Scheme | Role | |
| Stroke Research Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $13,000 | 2009 | 2009 |
| GNo:G0189810 | ||
2008 (3 grants)
A randomised controlled trial of mild hypothermia in acute ischaemic stroke$117,176
Funding Body: National Heart Foundation of Australia
| Project Team | ||
|---|---|---|
| Conjoint Professor Chris Levi, Professor Mark Parsons, Professor Christopher Bladin, Doctor Neil Spratt | ||
| Scheme | Role | |
| Grant-In-Aid | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $117,176 | 2008 | 2009 |
| GNo:G0187644 | ||
Is CaMKII autophosphorylation a mechanism of endogenous neuroprotection after stroke?$14,417
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Emeritus Professor John Rostas, Doctor Neil Spratt | ||
| Scheme | Role | |
| Pilot Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $14,417 | 2008 | 2008 |
| GNo:G0189110 | ||
Hypoxic culture chamber and low-pressure gas regulators$11,500
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt, Emeritus Professor John Rostas, Professor Mike Calford | ||
| Scheme | Role | |
| Equipment Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $11,500 | 2008 | 2008 |
| GNo:G0188544 | ||
2007 (2 grants)
Translation of novel neuroprotection and stroke recovery strategies from the laboratory to the clinic$171,750
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt | ||
| Scheme | Role | |
| Training (Postdoctoral) Fellowships - Health Professional Research Fellowship (Part-time) | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $171,750 | 2007 | 2011 |
| GNo:G0186772 | ||
Translation of novel neuroprotection and stroke recovery strategies from laboratory to the clinic$60,000
Funding Body: Sylvia & Charles Viertel Charitable Foundation
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt | ||
| Scheme | Role | |
| Medical Program - Viertel Clinical Investigators | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $60,000 | 2007 | 2008 |
| GNo:G0187573 | ||
2006 (1 grants)
Foundation for High Blood Pressure award.$60,000
Funding Body: Royal Australasian College of Physicians
| Project Team | ||
|---|---|---|
| Doctor Neil Spratt | ||
| Scheme | Role | |
| Research and Education Foundation | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $60,000 | 2006 | 2006 |
| GNo:G0187214 | ||
Edit
Research Supervision
| Number of current supervisions | 7 |
|---|---|
| Total current UoN PhD EFTSL | 5 |
For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.
Current Supervision
| Commenced | Proposed Completion | Program | Supervisor Type | Research Title |
|---|---|---|---|---|
| 2014 | 2018 | PhD (Human Physiology) | Principal Supervisor | Determining Factors within Cerebro-Spinal Fluid that Influence Intracranial Pressure Post-Stroke |
| 2014 | 2018 | PhD (Human Physiology) | Principal Supervisor | Cooling the Skin While Maintaining Normal Core Temperature to Prevent Intracranial Pressure Elevation and Improve Outcome after Stroke |
| 2012 | 2016 | PhD (Physiotherapy) | Co-Supervisor | Prevention of Stroke Through Improving Fitness |
| 2011 | 2015 | PhD (Human Physiology) | Principal Supervisor | The Effects and Mechanisms of Therapeutic Hypothermia on Intracranial Pressure Regulation Following Ischaemic Stroke in Rats |
| 2011 | 2015 | PhD (Human Physiology) | Principal Supervisor | A New Understanding of Factors Regulating Collateral Blood Flow during Ischaemic Stroke: Elevated Intracranial Pressure is a Potential Cause of Collateral Failure in Patients with Stroke-in-Progression |
| 2011 | 2015 | PhD (Medicine) | Principal Supervisor | Fitness Training in Stroke Trial |
| 2010 | 2014 | PhD (Human Physiology) | Principal Supervisor | Making Clots and Breaking Clots: Modelling Arterial Occlusion to Test Stroke Sonothrombolysis |
Past Supervision
| Year | Program | Supervisor Type | Research Title |
|---|---|---|---|
| 2013 | PhD (Human Physiology) | Principal Supervisor | Use of an Enriched Environment Post-Stroke: Translating from Bench to Bedside |
Edit
Dr Neil Spratt
| Work Phone | (02) 4921 6171 |
|---|---|
| Cell / Mobile Phone | 0403363981 |
| Fax | (02) 4921 7406 |
| Neil.Spratt@newcastle.edu.au | |
| Position | Associate Professor School of Biomedical Sciences and Pharmacy Faculty of Health and Medicine |
| Focus Area | Human Physiology |
| Office | MS502a, Medical Sciences , Callaghan University Drive Callaghan NSW 2308 Australia |
| URL: | www.newcastle.edu.au/profile/neil-spratt |
