Dr Madeleine Hinwood
Research Academic
School of Medicine and Public Health
- Email:madeleine.hinwood@newcastle.edu.au
- Phone:(02) 4014 3013
Career Summary
Biography
I am an Early Career Researcher who completed my PhD studies at the University of Newcastle in 2013. My PhD examined the relationship between psychological stress, neuroinflammation and glial changes in the prefrontal cortex in an effort to understand the potential neurobiology of illnesses such as depression. This work included a focus on the impact of antidepressants and other compounds on these processes.
Most recently, I have spent three years working in public health and health planning for a federal government program. This experience, combined with the research work completed during my PhD provided a natural progression into my current role as a research academic in clinical pharmacology. In this role I provide external evaluations of submissions to the Pharmaceutical Benefits Advisory Committee, and am currently developing a research profile in pharmacoepidemiology and medicines policy, with a particular focus on mental health care.
Qualifications
- Doctor of Philosophy, University of Newcastle
- Bachelor of Psychology (Honours), University of Newcastle
Keywords
- Mental Health
- Public health
- Epidemiology
- Pharmacoeconomics
- Preventative health care
- Pharmacology
- Social determinants of health
Languages
- English (Mother)
Fields of Research
| Code | Description | Percentage |
|---|---|---|
| 111599 | Pharmacology and Pharmaceutical Sciences not elsewhere classified | 40 |
| 119999 | Medical and Health Sciences not elsewhere classified | 30 |
| 170199 | Psychology not elsewhere classified | 30 |
Professional Experience
UON Appointment
| Title | Organisation / Department |
|---|---|
| Research Academic | University of Newcastle School of Medicine and Public Health Australia |
| Research Academic | Priority Research Centre (PRC) for Healthy Lungs | The University of Newcastle School of Medicine and Public Health Australia |
| Research Academic | University of Newcastle School of Medicine and Public Health Australia |
Publications
For publications that are currently unpublished or in-press, details are shown in italics.
Journal article (8 outputs)
| Year | Citation | Altmetrics | Link | ||||||||
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| 2013 |
Tynan RJ, Beynon SB, Hinwood M, Johnson SJ, Nilsson M, Woods JJ, Walker FR, 'Chronic stress-induced disruption of the astrocyte network is driven by structural atrophy and not loss of astrocytes', Acta Neuropathologica, 126 75-91 (2013) [C1]
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| 2013 |
Hinwood M, Tynan RJ, Charnley JL, Beynon SB, Day TA, Walker FR, 'Chronic Stress Induced Remodeling of the Prefrontal Cortex: Structural Re-Organization of Microglia and the Inhibitory Effect of Minocycline', CEREBRAL CORTEX, 23 1784-1797 (2013) [C1]
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| 2012 |
Tynan R, Weidenhofer JC, Hinwood M, Cairns MJ, Day TA, Walker FR, 'A comparative examination of the anti-inflammatory effects of SSRI and SNRI antidepressants on LPS stimulated microglia', Brain Behavior and Immunity, 26 469-479 (2012) [C1]
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| 2012 |
Hinwood M, Morandini J, Day TA, Walker FR, 'Evidence that microglia mediate the neurobiological effects of chronic psychological stress on the medial prefrontal cortex', Cerebral Cortex, 22 1442-1454 (2012) [C1]
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| 2011 |
Hinwood M, Tynan R, Day TA, Walker FR, 'Repeated social defeat selectively increases DeltaFosB expression and histone H3 acetylation in the infralimbic medial prefrontal cortex', Cerebral Cortex, 21 262-271 (2011) [C1]
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| 2010 |
Tynan R, Naicker S, Hinwood M, Nalivaiko E, Buller KM, Pow DV, et al., 'Chronic stress alters the density and morphology of microglia in a subset of stress-responsive brain regions', Brain Behavior and Immunity, 24 1058-1068 (2010) [C1]
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| 2009 |
Walker FR, Naicker S, Hinwood M, Dunn N, Day TA, 'Strain differences in coping behaviour, novelty seeking behaviour, and susceptibility to socially conditioned fear: A comparison between Wistar and Sprague Dawley rats', Stress: The International Journal on the Biology of Stress, 12 507-516 (2009) [C1]
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| 2008 |
Walker FR, Hinwood M, Masters LM, Dielenberg R, Day TA, 'Individual differences predict susceptibility to conditioned fear arising from psychosocial trauma', Journal of Psychiatric Research, 42 371-383 (2008) [C1]
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Conference (7 outputs)
| Year | Citation | Altmetrics | Link | ||
|---|---|---|---|---|---|
| 2012 |
Walker FR, Tynan R, Hinwood M, Woodworth SB, 'The role of microglia in cognitive disturbance: A new frontier in the neurobiology of stress', Brain, Behavior, and Immunity, San Diego, CA (2012) [E3]
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| 2011 |
Walker FR, Tynan R, Day TA, Ng A, Hinwood M, 'What have microglia got to do with it? New directions in the neurobiology of depression', Brain, Behavior, and Immunity, Chicago, Illinois (2011) [E3]
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| 2008 | Hinwood M, Walker R, Day TA, 'Characterisation and cellular specificity of the [triangle symbol] FOSB response to chronic social stress in rat infralimbic cortex', Australian and New Zealand Journal of Psychiatry, Newcastle, NSW (2008) [E3] | ||||
| 2007 |
Hinwood M, Walker FR, Day TA, 'Characterisation of fosB response in rat forebrain following exposure to chronic social stress (Poster)', 7th IBRO 2007 World Congress of Neuroscience Program, Melbourne (2007) [E3]
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| 2007 |
Walker FR, Hinwood M, Masters LM, Dielenberg R, Day TA, 'Individual differences predict susceptibility to conditioned fear arising from psychosocial trauma (Poster)', 7th IBRO 2007 World Congress of Neuroscience Program, Melbourne (2007) [E3]
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| 2006 |
Paton BK, Hinwood M, Budd TW, 'The effects of MR scanner noise on auditory thresholds: a psychoacoustic study using SAM white noise, pure tones and complex tones', Clinical EEG and Neuroscience V37, April 2006, Proceedings of the 15th Annual Conference of the Australasian Society for Psychophysiology, University of Wollongong, Sydney, Australia (2006) [E3]
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| 2006 |
Hinwood M, Paton BK, Budd TW, 'Acoustic masking by EPI gradient sounds on detection thresholds for amplitude modulation as a function of a modulation rate', Clinical EEG and Neuroscience V37, April 2006, Proceedings of the 15th Annual Conference of the Australasian Society for Psychophysiology, University of Wollongong, Sydney, Australia (2006) [E3]
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Grants and Funding
Summary
| Number of grants | 2 |
|---|---|
| Total funding | $5,825,025 |
Click on a grant title below to expand the full details for that specific grant.
20161 grants / $5,810,625
Provision of external evaluation of Pharmaceutical Benefits Advisory Committee (PBAC) and health technology related submissions$5,810,625
Funding body: Department of Health
| Funding body | Department of Health |
|---|---|
| Project Team | Ms Danielle Lang, Mr Rob Bell, Mr Marc Bevan, Ms Lynn Goon, Doctor Madeleine Hinwood, Mr Jarrod Bell, Doctor Emily Walkom |
| Scheme | Consultancy/Tender |
| Role | Investigator |
| Funding Start | 2016 |
| Funding Finish | 2020 |
| GNo | G1601071 |
| Type Of Funding | C2110 - Aust Commonwealth - Own Purpose |
| Category | 2110 |
| UON | Y |
20151 grants / $14,400
Translational Addiction Reseach$14,400
Funding body: Hunter Medical Research Institute
| Funding body | Hunter Medical Research Institute |
|---|---|
| Project Team | Conjoint Associate Professor Adrian Dunlop, Doctor Amanda Brown, Associate Professor Chris Dayas, Professor Jennifer Martin, Doctor Madeleine Hinwood |
| Scheme | Research Grant |
| Role | Investigator |
| Funding Start | 2015 |
| Funding Finish | 2018 |
| GNo | G1500923 |
| Type Of Funding | C3112 - Aust Not for profit |
| Category | 3112 |
| UON | Y |
Dr Madeleine Hinwood
Position
Research Academic
Newcastle Evaluation Group
School of Medicine and Public Health
Faculty of Health and Medicine
Contact Details
| madeleine.hinwood@newcastle.edu.au | |
| Phone | (02) 4014 3013 |
Office
| Building | Level 5, Clinical Sciences Building |
|---|---|
| Location | Mater Hospital, Edith Street Waratah , |
Research Networks
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