Dr Madeleine Hinwood

Dr Madeleine Hinwood

Research Academic

School of Medicine and Public Health

Career Summary

Biography

I am an Early Career Researcher who completed my PhD studies at the University of Newcastle in 2013. My PhD examined the relationship between psychological stress, neuroinflammation and glial changes in the prefrontal cortex in an effort to understand the potential neurobiology of illnesses such as depression.  This work included a focus on the impact of antidepressants and other compounds on these processes. 

Most recently, I have spent three years working in public health and health planning for a federal government program.  This experience, combined with the research work completed during my PhD provided a natural progression into my current role as a research academic in clinical pharmacology.  In this role I provide external evaluations of submissions to the Pharmaceutical Benefits Advisory Committee, and am currently developing a research profile in pharmacoepidemiology and medicines policy, with a particular focus on mental health care.


Qualifications

  • Doctor of Philosophy, University of Newcastle
  • Bachelor of Psychology (Honours), University of Newcastle

Keywords

  • Epidemiology
  • Mental Health
  • Pharmacoeconomics
  • Pharmacology
  • Preventative health care
  • Public health
  • Social determinants of health

Languages

  • English (Mother)

Fields of Research

Code Description Percentage
111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified 40
119999 Medical and Health Sciences not elsewhere classified 30
170199 Psychology not elsewhere classified 30

Professional Experience

UON Appointment

Title Organisation / Department
Research Academic University of Newcastle
School of Medicine and Public Health
Australia
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Journal article (8 outputs)

Year Citation Altmetrics Link
2013 Tynan RJ, Beynon SB, Hinwood M, Johnson SJ, Nilsson M, Woods JJ, Walker FR, 'Chronic stress-induced disruption of the astrocyte network is driven by structural atrophy and not loss of astrocytes', Acta Neuropathologica, 126 75-91 (2013) [C1]
DOI 10.1007/s00401-013-1102-0
Citations Scopus - 38Web of Science - 38
Co-authors Michael Nilsson, Rohan Walker, Sarah Johnson
2013 Hinwood M, Tynan RJ, Charnley JL, Beynon SB, Day TA, Walker FR, 'Chronic Stress Induced Remodeling of the Prefrontal Cortex: Structural Re-Organization of Microglia and the Inhibitory Effect of Minocycline', CEREBRAL CORTEX, 23 1784-1797 (2013) [C1]
DOI 10.1093/cercor/bhs151
Citations Scopus - 64Web of Science - 57
Co-authors Rohan Walker
2012 Tynan R, Weidenhofer JC, Hinwood M, Cairns MJ, Day TA, Walker FR, 'A comparative examination of the anti-inflammatory effects of SSRI and SNRI antidepressants on LPS stimulated microglia', Brain Behavior and Immunity, 26 469-479 (2012) [C1]
Citations Scopus - 108Web of Science - 101
Co-authors Rohan Walker, Judith Weidenhofer, Murray Cairns
2012 Hinwood M, Morandini J, Day TA, Walker FR, 'Evidence that microglia mediate the neurobiological effects of chronic psychological stress on the medial prefrontal cortex', Cerebral Cortex, 22 1442-1454 (2012) [C1]
Citations Scopus - 147Web of Science - 133
Co-authors Rohan Walker
2011 Hinwood M, Tynan R, Day TA, Walker FR, 'Repeated social defeat selectively increases DeltaFosB expression and histone H3 acetylation in the infralimbic medial prefrontal cortex', Cerebral Cortex, 21 262-271 (2011) [C1]
DOI 10.1093/cercor/bhq080
Citations Scopus - 27Web of Science - 22
Co-authors Rohan Walker
2010 Tynan R, Naicker S, Hinwood M, Nalivaiko E, Buller KM, Pow DV, et al., 'Chronic stress alters the density and morphology of microglia in a subset of stress-responsive brain regions', Brain Behavior and Immunity, 24 1058-1068 (2010) [C1]
DOI 10.1016/j.bbi.2010.02.001
Citations Scopus - 151Web of Science - 149
Co-authors Rohan Walker, Eugene Nalivaiko
2009 Walker FR, Naicker S, Hinwood M, Dunn N, Day TA, 'Strain differences in coping behaviour, novelty seeking behaviour, and susceptibility to socially conditioned fear: A comparison between Wistar and Sprague Dawley rats', Stress: The International Journal on the Biology of Stress, 12 507-516 (2009) [C1]
DOI 10.3109/10253890802673134
Citations Scopus - 9Web of Science - 8
Co-authors Rohan Walker
2008 Walker FR, Hinwood M, Masters LM, Dielenberg R, Day TA, 'Individual differences predict susceptibility to conditioned fear arising from psychosocial trauma', Journal of Psychiatric Research, 42 371-383 (2008) [C1]
DOI 10.1016/j.jpsychires.2007.01.007
Citations Scopus - 19Web of Science - 16
Co-authors Rohan Walker
Show 5 more journal articles

Conference (7 outputs)

Year Citation Altmetrics Link
2012 Walker FR, Tynan R, Hinwood M, Woodworth SB, 'The role of microglia in cognitive disturbance: A new frontier in the neurobiology of stress', Brain, Behavior, and Immunity (2012) [E3]
Co-authors Rohan Walker
2011 Walker FR, Tynan R, Day TA, Ng A, Hinwood M, 'What have microglia got to do with it? New directions in the neurobiology of depression', Brain, Behavior, and Immunity (2011) [E3]
Co-authors Rohan Walker
2008 Hinwood M, Walker R, Day TA, 'Characterisation and cellular specificity of the [triangle symbol] FOSB response to chronic social stress in rat infralimbic cortex', Australian and New Zealand Journal of Psychiatry (2008) [E3]
2007 Hinwood M, Walker FR, Day TA, 'Characterisation of fosB response in rat forebrain following exposure to chronic social stress (Poster)', 7th IBRO 2007 World Congress of Neuroscience Program (2007) [E3]
Co-authors Rohan Walker
2007 Walker FR, Hinwood M, Masters LM, Dielenberg R, Day TA, 'Individual differences predict susceptibility to conditioned fear arising from psychosocial trauma (Poster)', 7th IBRO 2007 World Congress of Neuroscience Program (2007) [E3]
Co-authors Rohan Walker
2006 Paton BK, Hinwood M, Budd TW, 'The effects of MR scanner noise on auditory thresholds: a psychoacoustic study using SAM white noise, pure tones and complex tones', Clinical EEG and Neuroscience V37, April 2006, Proceedings of the 15th Annual Conference of the Australasian Society for Psychophysiology (2006) [E3]
Co-authors Bryan Paton, Bill Budd
2006 Hinwood M, Paton BK, Budd TW, 'Acoustic masking by EPI gradient sounds on detection thresholds for amplitude modulation as a function of a modulation rate', Clinical EEG and Neuroscience V37, April 2006, Proceedings of the 15th Annual Conference of the Australasian Society for Psychophysiology (2006) [E3]
Co-authors Bill Budd, Bryan Paton
Show 4 more conferences
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Grants and Funding

Summary

Number of grants 1
Total funding $5,680,639

Click on a grant title below to expand the full details for that specific grant.


20161 grants / $5,680,639

Provision of external evaluation of Pharmaceutical Benefits Advisory Committee (PBAC) and health technology related submissions$5,680,639

Funding body: Department of Health

Funding body Department of Health
Project Team Ms Danielle Lang, Mr Rob Bell, Mr Marc Bevan, Ms Lynn Goon, Doctor Madeleine Hinwood, Mr Jarrod Bell, Doctor Emily Walkom
Scheme Consultancy/Tender
Role Investigator
Funding Start 2016
Funding Finish 2020
GNo G1601071
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y
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Dr Madeleine Hinwood

Position

Research Academic
Newcastle Evaluation Group
School of Medicine and Public Health
Faculty of Health and Medicine

Contact Details

Email madeleine.hinwood@newcastle.edu.au
Phone (02) 4921 1832

Office

Building Mater Hospital
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