Dr Saadallah Ramadan

Dr Saadallah Ramadan

Research Academic

Faculty of Health and Medicine (Medical Radiation Science)

Career Summary

Biography

Biography

Dr Ramadan is a Senior Lecturer within the School of Health Sciences, Faculty of Health. He received his PhD from the School of Chemistry, The University of Sydney in 2000. He spent two years studying red blood cells by NMR techniques, followed by studying the effect of non-steroidal anti-inflammatory drugs on rat stomach using NMR. He was then appointed as senior researcher at the Institute for Magnetic Resonance Research at Royal North Shore Hospital. In 2007, he moved to Boston, MA to take a position of Physicist at the Brigham and Women's Hospital, and became an Instructor in Radiology at Harvard Medical School. He was integrally involved in the development of MRI Research Policy at Brigham and Women’s Hospital. Technical interests include MRI/MRS pulse sequence development for Siemens (Syngo) platforms, where he worked on many different platforms. Spectroscopic as well as MRI diffusion-weighted sequences were developed for Syngo platforms. His research activities involve programming and evaluating novel MR imaging and spectroscopic techniques for investigation of human disease, as well as analysis and data post processing. Current focus areas include: breast, brain and prostate MR imaging and spectroscopy. Dr. Ramadan commenced a full-time position at the University of Newcastle in 2011.

Research Expertise

Dr Ramadan was initially trained in the field of NMR of partially aligned molecules in liquid crystal on a Bruker 400MHz, where he programmed many pulse sequence programs for his PHD program. He was also responsible for writing complex programs in Fortran77 and C++.  Dr Ramadan has renewed interest in NMR metabolomics in search of “bio-marker” of prostate disease as well as other human diseases. In 2004, Dr Ramadan travelled to North Carolina to learn pulse sequence programming and image reconstruction environment algorithms on Siemens whole body human MRI scanners. He has worked on 1.5, 3 and 7 tesla whole body magnets. He also designed many complex pulse sequences in spectroscopy, diffusion and exchange. He also has experience in designing new RF shapes, designing spectroscopic editing sequences, as well as localised two-dimensional correlation spectroscopy (L-COSY), and other variants of localised two-dimensional in vivo MRS, single voxel and multi-voxel (EP-COSI). Dr Ramadan has deep interest in the development and application of new magnetic resonance imaging/spectroscopic sequences to human disease. He is also interested in data post processing, development of automated processing pipelines for two-dimensional spectroscopic techniques, and designing sparse acquisition techniques to shorten long acquisition times.

Teaching Expertise

Dr Ramadan has experience in teaching Nuclear Magnetic Resonance (NMR), Magnetic Resonance Imaging (MRI), Magnetic Resonance Spectroscopy (MRS), Pulse Sequence Development, Data Post Processing, and Research Methodology.

Collaborations

Dr Ramadan is collaborating with a number of world leading researchers including:

  • Prof Albert Thomas, UCLA, CA, USA. Ongoing.
  • Dr Alex Lin, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA. Ongoing.
  • Prof John Aitken, University of Newcastle, Ongoing.
  • A/Prof Jeannette Lechner-Scott, Hunter Medical Research Institute. Ongoing.
  • Dr Ovidiu Andronesi, Martinos Center, Mass General Hospital, Boston, USA. Ongoing.

Qualifications

  • Doctor of Philosophy, University of Sydney

Keywords

  • Breast cancer
  • Data post processing
  • Glioma
  • In vivo diffusion studies
  • In vivo diffusion studies
  • Magnetic Resonance Imaging
  • Magnetic Resonance Spectroscopy
  • Muscle spectroscopy
  • One/Two-dimensional spectroscopy
  • Pulse sequence programming

Languages

  • English (Fluent)
  • Arabic (Mother)

Fields of Research

Code Description Percentage
029903 Medical Physics 30
030606 Structural Chemistry and Spectroscopy 30
110320 Radiology and Organ Imaging 40

Professional Experience

UON Appointment

Title Organisation / Department
Research Academic University of Newcastle
Faculty of Health and Medicine
Australia
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (3 outputs)

Year Citation Altmetrics Link
2014 Merugumala S, Ramadan S, Keenan W, Liao H, Wang LYJ, Lin A, 'Magnetic Resonance Spectroscopy', MRI in Psychiatry, Springer, New York 87-116 (2014) [B2]
DOI 10.1007/978-3-642-54542-9
2007 Ramadan S, Thomas MA, Mountford CE, 'Phase-rotated MR spectroscopy using dual-PRESS: theory and application in human brain', DataMining, Systems Analysis, and Optimization in Biomedicine, American Institute of Physics, Gainesvile, Florida, USA 277-291 (2007)
2006 Bourgeat P, Fripp J, Stanwell P, Ramadan S, Ourselin S, 'MR image segmentation using phase information and a novel multiscale scheme', Medical Image Computing and Computer-Assisted Intervention - Miccai 2006, Pt 2, Springer-Verlag Berlin, Berlin 920-927 (2006)

Journal article (38 outputs)

Year Citation Altmetrics Link
2015 Ramadan S, Arm J, Silcock J, Santamaria G, Buck J, Roy M, et al., 'Lipid and Metabolite Deregulation in BRCA1 and BRCA2 Genetic Mutations Response', RADIOLOGY, 277 615-616 (2015) [C3]
Co-authors Carolyn Mountford, Peter Stanwell
2015 Lin AP, Ramadan S, Stern RA, Box HC, Nowinski CJ, Ross BD, Mountford CE, 'Changes in the neurochemistry of athletes with repetitive brain trauma: preliminary results using localized correlated spectroscopy.', Alzheimers Res Ther, 7 13 (2015) [C1]
DOI 10.1186/s13195-015-0094-5
Citations Scopus - 6Web of Science - 2
Co-authors Carolyn Mountford
2015 Mountford C, Quadrelli S, Lin A, Ramadan S, 'Six fucose-alpha(1-2) sugars and alpha-fucose assigned in the human brain using in vivo two-dimensional MRS', NMR IN BIOMEDICINE, 28 291-296 (2015) [C1]
DOI 10.1002/nbm.3239
Co-authors Carolyn Mountford
2015 Leong KM, Lau P, Ramadan S, 'Utilisation of MR spectroscopy and diffusion weighted imaging in predicting and monitoring of breast cancer response to chemotherapy', Journal of Medical Imaging and Radiation Oncology, (2015) [C1]

Summary: Neoadjuvant chemotherapy (NACT) is the standard treatment option for breast cancer as more data shows that pathologic complete response (pCR) after NACT correlates with i... [more]

Summary: Neoadjuvant chemotherapy (NACT) is the standard treatment option for breast cancer as more data shows that pathologic complete response (pCR) after NACT correlates with improved prognosis. MRI is accepted as the best imaging modality for evaluating the response to NACT in many studies as compared with clinical examination and other imaging modalities. In vivo magnetic resonance spectroscopy (MRS) and diffusion-weighted imaging (DWI) studies have both emerged as potential tools to provide early response indicators based on the changes in the metabolites and the apparent diffusion coefficient (ADC) respectively. In this review article, we aim to discuss the strength and limitations of MRS and DWI in monitoring of early response breast cancer to NACT.

DOI 10.1111/1754-9485.12310
2015 Ramadan S, Arm J, Silcock J, Santamaria G, Buck J, Roy M, et al., 'Lipid and metabolite deregulation in the breast tissue of women carrying BRCA1 and BRCA2 genetic mutations', Radiology, 275 675-682 (2015) [C1]

© RSNA, 2015. Purpose: To use localized correlated spectroscopy (COSY) to assess for an altered biochemical state or states in breast tissue of women with BRCA gene mutations tha... [more]

© RSNA, 2015. Purpose: To use localized correlated spectroscopy (COSY) to assess for an altered biochemical state or states in breast tissue of women with BRCA gene mutations that potentially constitute preinvasive conditions. Materials and Methods: Institutional review board approval was obtained. Participants provided written informed consent. In vivo localized COSY images were recorded at 3 T in the breast tissue of women carrying BRCA1 (n = 9) or BRCA2 (n = 14) gene mutations and were compared with images in healthy control subjects with no family history of breast cancer (n = 10). All participants underwent contrast material-enhanced MR imaging and ultrasonography (US). Statistical significance was calculated with the Mann-Whitney two-sided nonparametric test. Results: No abnormality was recorded with MR imaging or US. Metabolite levels in the BRCA1 cohort were reduced by 79% (P = .014) when compared with triglycerides level, and there was a 19% increase in lipid unsaturation and triglyceride levels (P = .027 and P = .086, respectively) when compared with cellular cholesterol level. Cholesterol level was reduced by 47% (P = .027) when compared with diallylic lipid level. Metabolite levels in the BRCA2 cohort showed increased unsaturation of 21% (P = .030) relative to triglycerides level. Comparison of the BRCA1 and BRCA2 cohorts showed a 47% (P = .002) increase in cholesterol level in the BRCA2 cohort when compared with diallylic lipid level and a 52% (P = .003) increase when compared with triglycerides level. Levels of diallylic lipid, unsaturated lipid, triglycerides, and terminal methyl on the acyl chain are reduced by 46% (P = .002), 57% (P = .003), 66% (P = .003), and 29% (P = .010), respectively, when compared with cholesterol level. Conclusion: Localized COSY recorded significant changes in women with BRCA1 and BRCA2 gene mutations when compared with control subjects. If these changes are ultimately proven to be a premalignant stage, this method may prove useful in screening.

DOI 10.1148/radiol.15140967
Citations Scopus - 1
Co-authors Carolyn Mountford
2015 Ramadan S, Arm J, Silcock J, Santamaria G, Buck J, Roy M, et al., 'Response', Radiology, 277 615-616 (2015) [C3]
DOI 10.1148/radiol.2015151153
Co-authors Carolyn Mountford, Peter Stanwell
2015 Stanwell P, Gluch L, 'Lipid and metabolite deregulation in BRCA1 and BRCA2 genetic mutations', Radiology, 277 614-615 (2015) [C3]
DOI 10.1148/radiol.2015151153
Co-authors Peter Stanwell
2014 Knechtel L, Schall U, Cooper G, Ramadan S, Stanwell P, Jolly T, Thienel R, 'Transcranial direct current stimulation of prefrontal cortex: An auditory event-related potential and proton magnetic resonance spectroscopy study', Neurology Psychiatry and Brain Research, (2014) [C1]

Transcranial direct current stimulation (tDCS) is a non-invasive intervention altering neural plasticity by modulating neuronal excitability of pre- and postsynaptic neuron popula... [more]

Transcranial direct current stimulation (tDCS) is a non-invasive intervention altering neural plasticity by modulating neuronal excitability of pre- and postsynaptic neuron populations, which has been shown to improve depression symptoms and cognition. We investigated the effects of a single session of 20 min of 2 mA left-prefrontal anodal versus sham stimulation on auditory event-related potentials (ERPs) in 11 male and 5 female healthy subjects (mean age of 28.6 [SD 6.2] years) by employing a randomized single-blind crossover design. Stimulation effects on cortical glutamate (Glu) and glutamine (Glx) levels were subsequently measured in 12 of the 16 healthy subjects in a 3 T proton magnetic resonance spectroscopy scan. tDCS was associated with a significant increase of N1 amplitudes while smaller P3b amplitudes correlated with higher cortical Glu and Glx levels in the stimulated brain area when performing an auditory go/no-go discrimination task. tDCS did not change mismatch negativity, nor task performance or cortical Glu/Glx levels which, together with N1 amplitudes, depended on stimulation order ("sham" versus "active"). Increased N1 amplitudes are consistent with higher levels of cortical excitability following prefrontal anodal tDCS. The failure to replicate Glu/Glx changes with tDCS may have been masked by between-session carry-over effects while ceiling effects may have masked tDCS effects on task performance. © 2014 Elsevier GmbH. All rights reserved.

DOI 10.1016/j.npbr.2014.06.001
Citations Scopus - 3
Co-authors Peter Stanwell, Ulrich Schall, Renate Thienel
2013 Ramadan S, Lin A, Stanwell P, 'Glutamate and glutamine: A review of in vivo MRS in the human brain', NMR in Biomedicine, 26 1630-1646 (2013) [C1]

Our understanding of the roles that the amino acids glutamate (Glu) and glutamine (Gln) play in the mammalian central nervous system has increased rapidly in recent times. Many co... [more]

Our understanding of the roles that the amino acids glutamate (Glu) and glutamine (Gln) play in the mammalian central nervous system has increased rapidly in recent times. Many conditions are known to exhibit a disturbance in Glu-Gln equilibrium, and the exact relationships between these changed conditions and these amino acids are not fully understood. This has led to increased interest in Glu/Gln quantitation in the human brain in an array of conditions (e.g. mental illness, tumor, neuro-degeneration) as well as in normal brain function. Accordingly, this review has been undertaken to describe the increasing number of in vivo techniques available to study Glu and Gln separately, or pooled as 'Glx'. The present MRS methods used to assess Glu and Gln vary in approach, complexity, and outcome, thus the focus of this review is on a description of MRS acquisition approaches, and an indication of relative utility of each technique rather than brain pathologies associated with Glu and/or Gln perturbation. Consequently, this review focuses particularly on (1) one-dimensional 1H MRS, (2) two-dimensional 1H MRS, and (3) one-dimensional 13C MRS techniques. © 2013 John Wiley & Sons, Ltd.

DOI 10.1002/nbm.3045
Citations Scopus - 7Web of Science - 3
Co-authors Peter Stanwell
2013 Woodhams R, Inoue Y, Ramadan S, Hata H, Ozaki M, 'Diffusion-weighted Imaging of the Breast: Comparison of B-values 1000 s/mm(2) and 1500 s/mm(2)', MAGNETIC RESONANCE IN MEDICAL SCIENCES, 12 229-234 (2013) [C1]
DOI 10.2463/mrms.2012-0028
Citations Scopus - 1Web of Science - 1
2012 Biswas TK, Ramadan S, Ghosh SN, Bhattacharya RN, 'Uniqueness Of Refractive Index As An Effective Diagnostic Parameter For Brain Lesions: A Novel Noninvasive Technique To Predict Refractive Index From CT-MR Fusion Image By Applying Feynman¿s Equation', The Internet Journal of Radiology, 14 DOI-10.5580/2afa (2012)
DOI 10.5580/2afa
2011 Ramadan S, Andronesi A, Stanwell P, Lin A, Sorensen G, Mountford C, 'In Vivo Two Dimensional MR Spectroscopy Compares the Biochemistry of the Human Brain and Glioblastoma', Radiology, 259 540-549 (2011) [C1]
Citations Scopus - 14Web of Science - 9
Co-authors Peter Stanwell, Carolyn Mountford
2011 Woodhams R, Ramadan S, Stanwell PT, Sakamoto S, Hata H, Ozaki M, et al., 'Diffusion-weighted imaging of the breast: Principles and clinical applications', Radiographics, 31 1059-1084 (2011) [C1]
DOI 10.1148/rg.314105160
Citations Scopus - 56Web of Science - 40
Co-authors Peter Stanwell
2011 Verma G, Lipnick S, Ramadan S, Nagarajan R, Thomas M, 'Implementation of multi-echo-based correlated spectroscopic imaging and pilot findings in human brain and calf muscle', Journal of Magnetic Resonance Imaging, 34 262-269 (2011) [C1]
Citations Scopus - 2Web of Science - 1
2011 Ramadan S, Mountford C, 'Adiabatic Localized Correlation Spectroscopy (AL-COSY) - Application in Muscle and Brain', Journal of Magnetic Resonance Imaging, 33 1447-1455 (2011) [C1]
Citations Scopus - 4Web of Science - 4
Co-authors Carolyn Mountford
2010 Mountford CE, Stanwell PT, Lin A, Ramadan S, Ross B, 'Neurospectroscopy: The past, present and future', Chemical Reviews, 110 3060-3086 (2010) [D1]
DOI 10.1021/cr900250y
Citations Scopus - 48Web of Science - 36
Co-authors Carolyn Mountford, Peter Stanwell
2010 Andronesi OC, Ramadan S, Mountford CE, Sorensen AG, 'Low-power adiabatic sequences for in vivo localized two-dimensional chemical shift correlated MR spectroscopy', Magnetic Resonance in Medicine, 64 1542-1556 (2010) [C1]
DOI 10.1002/mrm.22535
Citations Scopus - 13Web of Science - 13
Co-authors Carolyn Mountford
2010 Lipnick S, Verma G, Ramadan S, Furuyama J, Thomas MA, 'Echo Planar Correlated Spectroscopic Imaging:Implementation and Pilot Evaluation in Human Calf In Vivo', Magnetic Resonance in Medicine, 64 947-956 (2010) [C1]
DOI 10.1002/mrm.22499
Citations Scopus - 17
2010 Ramadan S, Mulkern R, 'Comment on ADC Reductions in Post-Contrast Breast Tumors', Journal of Magnetic Resonance Imaging, 31 262-262 (2010) [C3]
DOI 10.1002/jmri.21972
2010 Stanwell PT, Siddall P, Keshava N, Cocuzzo D, Ramadan S, Lin A, et al., 'Neuro magnetic resonance spectroscopy using wavelet decomposition and statistical testing identifies biochemical changes in people with spinal cord injury and pain', Neuroimage, 53 544-552 (2010) [C1]
DOI 10.1016/j.neuroimage.2010.06.051
Citations Scopus - 27Web of Science - 20
Co-authors Carolyn Mountford, Peter Stanwell
2010 Andronesi OC, Ramadan S, Ratai EM, Jennings D, Mountford CE, Sorensen GA, 'Spectroscopic imaging with improved gradient modulated constant adiabaticity pulses on high-field clinical scanners', Journal of Magnetic Resonance, 203 283-293 (2010) [C1]
Citations Scopus - 24Web of Science - 23
Co-authors Carolyn Mountford
2010 Ramadan S, Ratai EM, Wald LL, Mountford CE, 'IN VIVO 1D and 2D Correlation MR Spectroscopy of the Soleus Muscle at 7T', Journal of Magnetic Resonance, 204 91-98 (2010) [C1]
Citations Scopus - 19Web of Science - 16
Co-authors Carolyn Mountford
2010 Nagarajan R, Ramadan S, Thomas MA, 'Detection of Amide and Aromatic Proton Resonances of Human Brain Metabolites Using Localized Correlated Spectroscopy Combined with Two Different Water Suppression Schemes', Magnetic Resonance Insights, 4 1-9 (2010) [C1]
2009 Ramadan S, 'Diffusion-Exchange Weighted Imaging', Magnetic Resonance Insights, 11-19 (2009) [C1]
2009 Ramadan S, Mountford C, 'Two-Dimensional Magnetic Resonance Spectroscopy in Biopsy and In Vivo 161-199 (2009)
Citations Scopus - 6Web of Science - 4
Co-authors Carolyn Mountford
2009 Thomas MA, Lipnick S, Velan S, Liu S, Banakar S, Binesh N, et al., 'Investigation of breast cancer using two-dimensional MRS', NMR in Biomedicine, 22 77-91 (2009) [C1]
Citations Scopus - 20
2009 Mountford CE, Ramadan SA, Stanwell PT, Malycha PL, 'Proton MRS of the Breast in the clinical setting.', NMR in Biomedicine, 22 54-64 (2009) [C1]
DOI 10.1002/nbm.1301
Citations Scopus - 35Web of Science - 27
Co-authors Carolyn Mountford, Peter Stanwell
2008 Mountford CE, Stanwell P, Ramadan S, 'Breast MR Imaging at 3.0T', Radiology, 248 319-320 (2008) [C3]
2008 Swindle P, Ramadan S, Stanwell PT, McCredie S, Russell P, Mountford C, 'Proton magnetic resonance spectroscopy of the central, transition and peripheral zones of the prostate: Assignments and correlation with histopathology.', Magnetic Resonance Materials in Physics Biology and Medicine, 21 423-434 (2008) [C1]
DOI 10.1007/s10334-008-0136-0
Citations Scopus - 19Web of Science - 13
Co-authors Carolyn Mountford, Peter Stanwell
2007 Bourgeat P, Fripp J, Stanwell P, Ramadan S, Ourselin S, 'MR image segmentation of the knee bone using phase information', Med Image Anal, 11 325-335 (2007)
DOI 10.1016/j.media.2007.03.003
2007 Ramadan S, 'Phase-Rotation in In-vivo Localised Spectroscopy', Concepts in Magnetic Resonance, 30 147-153 (2007)
2005 Ramadan S, Bonin AM, Kennedy BJ, Hambley TW, Lay PA, 'Nuclear magnetic resonance analysis of indomethacin-induced gastric ulcers', Chemical Research in Toxicology, 18 123-128 (2005)
2004 Ramadan S, Hambley TW, Kennedy BJ, Lay PA, 'NMR spectroscopic characterization of copper(II) and zinc(II) complexes of indomethacin', Inorganic Chemistry, 43 2943-2946 (2004)
2004 Kuchel PW, Bubb WA, Ramadan S, Chapman BE, Philp DJ, Coen M, et al., 'P-31 MAS-NMR of human erythrocytes: Independence of cell volume from angular velocity', Magnetic Resonance in Medicine, 52 663-668 (2004)
2003 Ramadan S, Field LD, Pierens GK, 'Multiple quantum nuclear magnetic resonance spectra of partially oriented styrene in a nematic phase', Molecular Physics, 101 1813-1818 (2003)
2003 Field LD, Ramadan S, 'Multiple quantum NMR spectra of toluene and p-bromotoluene partially aligned in a nematic phase', Magnetic Resonance in Chemistry, 41 933-938 (2003)
2002 Field LD, Ramadan S, Pierens GK, 'Multiple-quantum NMR spectra of partially oriented indene: A new approach to estimating order in a nematic phase', Journal of Magnetic Resonance, 156 64-71 (2002)
1995 Atkinson EJ, Clezy PS, Leung CWF, Ramadan S, Salek A, Zhuo MX, 'The Chemistry of Pyrrolic Compounds .70. the Synthesis of Model Porphyrins as an Aid to the Recognition of Chlorobium-Derived Petroporphyrins in the Julia-Creek Oil-Shale Deposit', Australian Journal of Chemistry, 48 1873-1885 (1995)
Show 35 more journal articles

Conference (43 outputs)

Year Citation Altmetrics Link
2015 Ribbons K, Quadrelli S, Lechner-Scott J, Al-Iedani O, Arm J, Ramadan S, '2D MR spectroscopy can identify molecules differentiating MS from healthy controls', MULTIPLE SCLEROSIS JOURNAL (2015) [O1]
2015 Ribbons K, Quadrelli S, Lechner-Scott J, Al-Iedani O, Arm J, Mountford C, Ramadan S, '2D MR spectroscopy can identify molecules differentiating MS from healthy controls', MULTIPLE SCLEROSIS JOURNAL (2015) [E3]
Co-authors Carolyn Mountford
2014 Ramadan S, Arm J, Silcock J, Santamaria G, Buck J, Roy M, et al., 'Lipid Deregulation in Women Carrying the BRCA Mutations: Non invasive evaluation by two-dimensional Spectroscopy' (2014) [E3]
2014 Ramadan S, Arm J, Silcock J, Santamaria G, Buck J, Roy M, et al., 'LIPID AND METABOLITE DEREGULATION IN THE BREAST TISSUE OF WOMEN CARRYING BRCA1 AND BRCA2 GENETIC MUTATIONS', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2014) [E3]
DOI 10.1111/ajco.12336
Co-authors Carolyn Mountford
2013 Ramadan S, Burrows TL, Pursey KM, Stanwell PT, 'Brain MRS after consumption of commercially available energy drink', Proceedings of the International Society for Magnetic Resonance in Medicine (2013) [E3]
Co-authors Peter Stanwell, Tracy Burrows
2013 Sun Y, Dunn MC, Ramadan S, Jones KL, Green A, Ligon K, Kung AL, 'MR Imaging and Spectroscopy for evaluation of brain tumor metabolic profiles in primary glioblastoma multiforme xenografts', Proceedings of the International Society of Magnetic Resonance in Medicine (2013) [E3]
2012 Ramadan S, Liao HJ, Lin A, Mountford C, 'Different Types of COSY Applied To Study Glutamate and Glutamine in a Clinical Scanner' (2012) [E3]
2012 Lin A, Liao HJ, Cadena A, Ramadan S, Molina I, McCarley R, 'Comparison of Cerebral Glutamate and GABA in Schizotypal Personality Disorder using Spectral Editing and 2D Correlated Spectroscopy' (2012) [E3]
2012 Peled S, Ramadan S, Westin CF, 'Measuring Cell Permeability with Diffusion-Weighted Simultaneous Spin-Echo and Stimulated Echo EPI' (2012) [E3]
2012 Ramadan S, Burrows T, Pursey K, Stanwell P, 'Brain MRS after Consumption of Commercially Available Energy Drink' (2012) [E3]
2012 Ramadan S, Biswas T, Heberlein K, Brown M, Lin A, 'Estimation of GABA and Glutamergic Contents in Occipital Lobe and Cerebellum By1H MR Spectroscopy' (2012)
2012 Lin A, Merugumala S, Ramadan S, Liao HJ, Fiorina P, Chandraker AK, Mountford C, 'Optimization and Characterization of Two-Dimensional Correlated Spectroscopy of Transplanted Kidney' (2012) [E3]
2012 Ramadan S, Baltzer PAT, Lin A, Stanwell PT, Box H, Kaiser WA, Mountford CE, 'L-COSY of breast cancer at 3T', European Journal of Radiology (2012) [E1]
Co-authors Peter Stanwell, Carolyn Mountford
2011 Ramadan S, Andronesi OC, Stanwell P, Lin A, Sorensen AG, Mountford C, 'In vivo L-COSY MRS of Healthy Brain and Glioblastoma' (2011) [E3]
2011 Ramadan S, Box H, Baltzer PAT, Lin A, Stanwell P, Gombos E, et al., 'Distinction of Invasive Lobular Carcinoma, Invasive Ductal Carcinoma, and Healthy Breast Tissue In Vivo With L-COSY at 3T' (2011) [E3]
2011 Shic F, Lin A, Stanwell P, Ramadan S, Gombos E, Mountford C, 'Time-Frequency Analysis of In Vivo MRS of the Breast Improves Cancer Detection' (2011) [E3]
Co-authors Peter Stanwell
2011 Cocuzzo D, Keshava N, Lin AP, Ramadan S, Mountford C, 'Algorithms for Characterizing Brain Metabolites in Two-Dimensional in Vivo MR Correlation Spectroscopy', Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (2011) [E1]
Citations Scopus - 2
Co-authors Carolyn Mountford
2010 Lin A, Ramadan S, Stanwell P, Luu T, Celestin J, Bajwa Z, Mountford C, 'In vivo L-COSY MR Distinguishes Glutamate from Glutamine and Shows Neuropathic Pain to Cause a Buildup of Glutamine' (2010) [E3]
2010 Ramadan S, Mulkern RV, Mountford CE, '¿-3 fatty acid detection by L-COSY in human bone marrow at 3T' (2010)
2010 Andronesi OC, Ramadan S, Mountford CE, Sorensen AG, 'Towards a localized low power adiabatic 2D TOCSY for in-vivo use on clinical platforms' (2010) [E3]
2010 Huda A, Ramadan S, Kumar R, Thomas MA, 'Clinical Dosimetry via MRS at 3T' (2010) [E3]
2010 Verma G, Lipnick SL, Rajakumar N, Ramadan S, Thomas MA, 'Reproducibility of ME-COSI in Human Brain and Phantom' (2010) [E3]
2009 Rajakumar N, Ramadan S, 'Detection of J-Coupled Cross Peaks Between Amide and Aliphatic Protons of N-Acetylaspartate in Human Brain using Localized Correlated Spectroscopy' (2009) [E3]
2009 Ramadan S, Ratai EM, Andronesi OC, Sorensen AG, Mountford CE, 'Adiabatic L-COSY at 7T' (2009) [E3]
2009 Ramadan S, Ratai EM, Seethamraju R, Mountford CE, 'Phase-Rotation for Spectroscopic Motion Correction' (2009) [E3]
2009 Thomas MA, Lipnick S, Verma G, Rajakumar N, Wilson N, Singhal A, et al., 'Recent Progress on the Implementation and Evaluation of Single- and Multi-voxel versions of 2D MR Spectroscopy Using Whole Body MRI Scanners' (2009) [E3]
2009 Ramadan S, Mountford C, 'Cross Peak Enhancement in Constant-Time COSY (CT-COSY)' (2009) [E3]
2009 Verma G, Rajakumar N, Lipnick S, Ramadan S, Thomas MA, 'Two dimensional Localized Correlated spectroscopy: Detection of J-coupled Cross Peaks between Amide and Aliphatic Protons in Human Brain and Elimination of Artifactual Diagonals' (2009) [E3]
2009 Ramadan S, Thomas MA, 'Phase-sensitive Localized COSY (PS-LCOSY)', ISMRM 17th Scientific Meeting & Exhibition 2009 Proceedings (2009) [E3]
2009 Verma G, Ramadan S, Rajakumar N, Lipnick SL, Liu XS, Thomas MA, 'Multi-Echo Acquisition Based J-Resolved Spectroscopic Imaging on a Whole-Body 3T Scanner' (2009) [E3]
2009 Liu X, Verma G, Lipnick S, Ramadan S, Debruhl N, Thomas MA, 'Turbo-Spin-Echo Based Correlated Spectroscopic Imaging of Breast Tissues In Vivo: A Preliminary Study' (2009) [E3]
2009 Andronesi OC, Ramadan S, Ratai EM, Mountford C, Sorensen AG, 'Gradient offset independent adiabatic pulses for high-field MR spectroscopy on clinical scanners' (2009) [E3]
2009 Lipnick S, Ramadan S, Verma G, Thomas MA, 'Echo-Planar based Correlated Spectroscopic Imaging (EP-COSI): Implementation and Evaluation in Human Skeletal Muscle Using a 3T MRI Scanner and an 8-channel Knee Coil' (2009) [E3]
2008 Frias-Martinez E, Rajakumar N, Ramadan S, Banakar S, Liu X, Singhal A, Thomas MA, 'A Pilot Comparison of 2D and 1D MR Spectroscopic Quantitation of Metabolites in Healthy Human Brain at 3T' (2008) [E3]
2008 Ramadan S, Ratai EM, Wald LL, Wiggins GC, Mountford CE, '1D and 2D Correlation Spectroscopy of Muscle at 7T' (2008) [E3]
2008 Thomas MA, Velan S, Ramadan S, Rajakumar N, Margolis DJ, Gomez M, et al., 'MEGA-editing of Spermine/Spermidine in Healthy Human Prostates using External Phased-Array Coil Assembly' (2008) [E3]
2008 Verma G, Ramadan S, Lipnick S, Rajakumar N, Thomas MA, 'Applications of Turbo Spin Echo Enhanced 2D Correlated Spectroscopic Imaging' (2008) [E3]
2008 Thomas MA, Lipnick S, Verma G, Rajakumar N, Liu X, Ramadan S, et al., 'Adding 2nd Spectral Dimension to Single- and Multi-Voxel Based MR Spectroscopy' (2008) [E3]
2008 Verma G, Ramadan S, Lipnick S, Rajakumar N, Thomas MA, 'Turbo Spin Echo Based Spatially Resolved Correlated Spectroscopic Imaging' (2008) [E3]
2008 Frias-Martinez E, Rajakumar N, Liu X, Singhal A, Banakar S, Lipnick S, et al., 'ProFit-based Quantitation of Cerebral Metabolites using 2D L-COSY at 3T' (2008) [E3]
2008 Ramadan S, Ratai EM, Wald LL, Wiggins GC, Mountford CE, 'Bone Marrow 1D and 2D Correlation MR Spectroscopy at 7T' (2008) [E3]
2008 Ramadan S, Ratai EM, Wald LL, Wiggins GC, Mountford CE, 'Double Quantum Spectroscopy Using Phase Rotation at 7T' (2008) [E3]
2006 Ramadan S, Mountford C, 'Diffusion Exchange Weighted (DEW) Imaging' (2006)
Show 40 more conferences

Other (1 outputs)

Year Citation Altmetrics Link
2009 Ramadan S, Stanwell P, Seethamraju R, Mountford C, 'TrueForm Retains the Spectral Integrity on the Verio', ( pp.120-123) (2009) [O1]
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Grants and Funding

Summary

Number of grants 15
Total funding $3,867,590

Click on a grant title below to expand the full details for that specific grant.


20161 grants / $20,000

Magnetic resonance spectroscopic GABA scanning of brain of MS patients for biochemical changes$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Saadallah Ramadan, Conjoint Associate Professor Jeannette Lechner-Scott
Scheme Project Grant
Role Lead
Funding Start 2016
Funding Finish 2016
GNo G1600306
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20151 grants / $14,000

Improving head and neck radiation therapy using MRI based treatment $14,000

Funding body: Calvary Mater Newcastle

Funding body Calvary Mater Newcastle
Scheme Project Grant
Role Investigator
Funding Start 2015
Funding Finish 2016
GNo
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON N

20145 grants / $691,090

The effect of Gilenya (Fingolimod) on cognitive performance in multiple sclerosis$416,000

Funding body: Novartis Pharmaceuticals Australia Pty Limited

Funding body Novartis Pharmaceuticals Australia Pty Limited
Project Team

Lechner-Scott, J

Scheme Project Grant
Role Investigator
Funding Start 2014
Funding Finish 2018
GNo
Type Of Funding Aust Competitive - Non Commonwealth
Category 1NS
UON N

Effect of Dimethyl Fumarate (Tecfidera) on microstructure and biochemistry in the brain of MS patients$200,090

Funding body: Biogen Idec Australia Pty Ltd

Funding body Biogen Idec Australia Pty Ltd
Project Team

Lechner-Scott, J

Scheme Research Project
Role Investigator
Funding Start 2014
Funding Finish 2016
GNo
Type Of Funding Aust Competitive - Non Commonwealth
Category 1NS
UON N

Magnetic Resonance Spectroscopic Imaging: improved accuracy of prostate cancer diagnosis and follow-up$25,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Saadallah Ramadan, Associate Professor Peter Stanwell, Dr Peter Lau
Scheme Project Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1400952
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Pilot Study to identify non-invasively a pre-invasive change to the breast in High Risk women$25,000

Funding body: Hunter Cancer Research Alliance

Funding body Hunter Cancer Research Alliance
Project Team

Mountford, C

Scheme Pilot
Role Investigator
Funding Start 2014
Funding Finish 2015
GNo
Type Of Funding External
Category EXTE
UON N

Pilot study to develop technology to monitor the effect of neoadjuvant therapy prior to surgery$25,000

Funding body: Hunter Cancer Research Alliance

Funding body Hunter Cancer Research Alliance
Project Team

Mountford, C

Scheme Pilot
Role Investigator
Funding Start 2014
Funding Finish 2015
GNo
Type Of Funding External
Category EXTE
UON N

20131 grants / $1,050,000

Biomarkers for Mild Traumatic Brain Injury, Blast Injury and Post Traumatic Stress Disorder$1,050,000

Goal: The goal of this project is to examine the clinical presentation and biomarkers that accompany chronic traumatic encephalopathy (CTE; also known as dementia pugilistica), a preventable cause of dementia. CTE is caused by repetitive head trauma, including both concussive and subconcussive blows to the head, such as those experienced by the millions of youth, high school, college, and professional athletes involved in contact sports.

Funding body: U.S. Department of Defense

Funding body U.S. Department of Defense
Project Team

Mountford, C

Scheme Gulf War Illness Research Program (GWIRP): Investigator-Initiated Research Award
Role Investigator
Funding Start 2013
Funding Finish 2016
GNo
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON N

20122 grants / $23,500

Equipment Grant Round $22,000

Funding body: The University of Newcastle

Funding body The University of Newcastle
Scheme Equipment Grant
Role Lead
Funding Start 2012
Funding Finish 2013
GNo
Type Of Funding Internal
Category INTE
UON N

Proceedings of the International Society of Magnetic Resonance in Medicine, Melbourne, Victoria, 5 - 11 May 2011$1,500

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Doctor Saadallah Ramadan
Scheme Travel Grant
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1200421
Type Of Funding Internal
Category INTE
UON Y

20112 grants / $380,000

Metabolism and Perfusion in Autism Spectrum Disorders Using 3 tesla MRI$280,000

Funding body: National Institute of Neurological Disorders (NIH)

Funding body National Institute of Neurological Disorders (NIH)
Project Team

Herbert, M

Scheme Project
Role Investigator
Funding Start 2011
Funding Finish 2013
GNo
Type Of Funding International - Competitive
Category 3IFA
UON N

Neurochemical and Multimodal Biomarkers for Chronic Traumatic Encephalopathy$100,000

Funding body: Center for Integration of Medicine and Innovative Technology (CIMIT)

Funding body Center for Integration of Medicine and Innovative Technology (CIMIT)
Project Team

Lin, A

Scheme Project Grant
Role Investigator
Funding Start 2011
Funding Finish 2012
GNo
Type Of Funding External
Category EXTE
UON N

20101 grants / $1,100,000

Identifying biomarkers that distinguish post-traumatic stress disorder and mild traumatic brain injury using advanced magnetic resonance spectroscopy$1,100,000

We propose a multi-parametric approach using major advances on spectroscopic methods and neuroimaging
to identify biomarkers that can be used to distinguish between post-traumatic stress disorder, traumatic brain injury, and their co-occurrence. This will be achieved in part by correlating quantitative MR spectroscopy results with behavioral and neuropsychological metrics using newly developed algorithmic approaches that are capable of revealing discriminating metabolic markers in MR spectroscopy measurements.

Funding body: U.S. Department of Defense

Funding body U.S. Department of Defense
Project Team

Lin, A

Scheme Traumatic Brain Injury (PH/TBI) Research Program
Role Investigator
Funding Start 2010
Funding Finish 2013
GNo
Type Of Funding External
Category EXTE
UON N

20091 grants / $169,000

Pattern Recognition Methods for Comparison of MR Spectral Data Using Wavelet Decomposition & Statistical Testing: Further Development and Testing In vivo$169,000

Funding body: Draper Laboratory, MA, USA

Funding body Draper Laboratory, MA, USA
Project Team

Keshava, N

Scheme University Research and Development Grant
Role Investigator
Funding Start 2009
Funding Finish 2011
GNo
Type Of Funding International - Competitive
Category 3IFA
UON N

20051 grants / $420,000

Development of Novel Two-dimensional Techniques for Magnetic Resonance In-vivo Spectroscopy$420,000

This project aims to develop novel single-voxel based two dimensional magnetic resonance spectroscopy techniques to allow detailed chemical information to be collected, unambiguously assigned and quantified from a particular volume of interest in situ from human organs initially the brain.

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team

Mountford, C

Scheme Discovery Projects
Role Investigator
Funding Start 2005
Funding Finish 2008
GNo
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON N
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Research Supervision

Number of supervisions

Completed1
Current4

Total current UON EFTSL

PhD1.48

Current Supervision

Commenced Level of Study Research Title / Program / Supervisor Type
2015 PhD Magnetic Resonance Spectroscopy (MRS) in the Diagnosis and Management of Multiple Sclerosis.
PhD (Medical Radiation Sc), Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2015 PhD Improved Prostate Tumour Identification and Delineation Using Multiparametric Magnetic Resonance Imaging
PhD(Magnetic Resonance in Med), Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2014 PhD Magnetic Resonance Spectroscopy (MRS) to Document Changes in Neurochemistry
PhD(Magnetic Resonance in Med), Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
2014 PhD Fast magnetic resonance spectroscopic imaging for whole brain metabolic profiling of multiple sclerosis
PhD (Medical Radiation Sc), Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor

Past Supervision

Year Level of Study Research Title / Program / Supervisor Type
2015 PhD Transcranial Direct Current Stimulation Effects on Auditory Event-Related Potentials in Schizophrenia
PhD (Psychiatry), Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
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Research Opportunities

Development of macromolecules-free GABA editing sequence

Current GABA editing sequences co-edit macromolecules along with GABA. The aim of this project is to develop more selective pulses that can fit within the optimal 68ms TE, that can selectively edit GABA alone.

PHD

Health Sciences

12/04/2016 - 1/12/2016

Contact

Doctor Saadallah Ramadan
University of Newcastle
Faculty of Health and Medicine
saadallah.ramadan@newcastle.edu.au

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Dr Saadallah Ramadan

Position

Research Academic
Faculty of Health and Medicine

Focus area

Medical Radiation Science

Contact Details

Email saadallah.ramadan@newcastle.edu.au
Phone (02) 4042 0573
Mobile 0435 379 732
Links Research Networks
Research Networks
Research Networks
Research Networks

Office

Room Hunter Building
Building Hunter Building
Location Callaghan
University Drive
Callaghan, NSW 2308
Australia
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