Dr Vanessa Murphy

Dr Vanessa Murphy

Senior Lecturer

School of Medicine and Public Health

Career Summary

Biography

Dr Vanessa Murphy is a postdoctoral research scientist investigating the characteristics, mechanisms and consequences of asthma exacerbations during pregnancy and their health impact on both the mother and the baby. She began in this field full-time in 1999, with her PhD studies on the effects of maternal asthma on placental function and fetal development winning numerous awards, nationally and internationally. In 2004, with a competitive 3 year fellowship from the Hunter Medical Research Institute, she commenced her post-doctoral studies with the Centre for Asthma and Respiratory Diseases, under the supervision of Prof Peter Gibson, where she is continuing to build on her expertise in the area of asthma exacerbations and airway inflammation during pregnancy. Since 2006, Dr Murphy has pursued her research career part-time, and has taken three significant breaks from her career while having children. In 2007 she received her first project grant from the NHMRC, which investigated the mechanisms, characteristics and consequences of viral infections on asthma exacerbations during pregnancy, and she is currently funded by a part-time NHMRC fellowship which was also awarded in 2007. She is involved as an associate investigator on the NHMRC funded “Managing asthma in pregnancy” (MAP) randomised controlled trial, which successfully reduced the rate of severe exacerbations in pregnancy by managing treatment changes with the use of an objective marker of airway inflammation. This resulted in a high impact publication in Lancet in 2011. With pilot funding from HMRI, this study has now been extended to a birth cohort follow-up study, investigating the links between maternal asthma in pregnancy and the development of asthma in childhood, in collaboration with Paediatrician A/Prof Joerg Mattes and Prof Peter Gibson. A further highlight of recent years has been working on an exciting collaboration with the world leader in the field of asthma during pregnancy, Prof Michael Schatz and colleagues in San Diego, USA. Together, we have completed the first systematic review and meta-analysis examining the risks of adverse perinatal outcomes in women with asthma, which has resulted in a publication in the British Journal of Obstetrics and Gynaecology in 2011. Dr Murphy has been invited to write reviews several times, and this year was invited to speak at the European Respiratory Society Conference in Amsterdam in September on the management of asthma during pregnancy, demonstrating her recognition internationally in the field of asthma during pregnancy.

Research Expertise

Vanessa's research expertise is in the area of asthma during pregnancy, covering the effects of asthma on pregnancy outcomes, the management of asthma during pregnancy, and the mechanisms of viral infection in pregnancy. 


Qualifications

  • PhD, University of Newcastle
  • Bachelor of Medicinal Chemistry (Honours), University of Wollongong

Keywords

  • asthma
  • pregnancy

Fields of Research

Code Description Percentage
110299 Cardiorespiratory Medicine and Haematology not elsewhere classified 35
160599 Policy and Administration not elsewhere classified 30
111499 Paediatrics and Reproductive Medicine not elsewhere classified 35

Professional Experience

UON Appointment

Title Organisation / Department
Senior Lecturer University of Newcastle
School of Medicine and Public Health
Australia
Senior Lecturer Priority Research Centre (PRC) for Healthy Lungs | The University of Newcastle
School of Medicine and Public Health
Australia
Senior Lecturer University of Newcastle
School of Medicine and Public Health
Australia

Academic appointment

Dates Title Organisation / Department
1/12/2007 - 1/3/2013 Australian Part-time Research Fellowship

NHMRC - Early Career Fellowships (Formerly Postdoctoral Training Fellowships)

University of Newcastle
School of Medicine and Public Health
Australia
1/3/2004 -  Post Doctoral Research Fellow University of Newcastle
School of Medicine and Public Health
Australia

Awards

Research Award

Year Award
2005 Young Scientist Sponsorship
European Respiratory Society
2005 Ian Potter Foundation Travel Grant
Ian Potter Foundation
2004 New Investigator Award
Unknown
2003 Elsevier Science New Investigator Award
Unknown
2002 Australian Society for Medical Research (ASMR) Research Award
Unknown
2002 Best Oral Presentation by a Student
Unknown
2001 Medibank Private Student Researcher Award
Unknown
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (4 outputs)

Year Citation Altmetrics Link
2019 Murphy V, Jensen M, Campbell L, Gibson P, 'Asthma interrelationships with pregnancy', Asthma, Allergic and Immunologic Diseases during Pregnancy: A Guide to Management, Springer Nature Switzerland AG, Switzerland 29-45 (2019) [B1]
DOI 10.1007/978-3-030-03395-8_3
Co-authors Linda E Campbell, Peter Gibson, Megan Jensen
2010 Murphy VE, Gibson PG, 'Asthma and rhinitis in pregnancy', Allergy Frontiers: Therapy and Prevention, Springer, Berlin 485-497 (2010) [B1]
Co-authors Peter Gibson
2009 Murphy VE, Gibson PG, 'Asthma in pregnancy', Pulmonary Problems in Pregnancy, Humana Press, New York 143-164 (2009) [B1]
DOI 10.1007/978-1-59745-445-2
Co-authors Peter Gibson
2006 Murphy VE, Smith R, Giles WB, Clifton VL, 'The role of the mother, placenta, and fetus in the control of fetal growth during human pregnancy', Perinatal Programming: Early Life Determinants of Adult Health & Disease, Taylor & Francis, London 3-16 (2006) [B1]
Co-authors Roger Smith
Show 1 more chapter

Journal article (78 outputs)

Year Citation Altmetrics Link
2020 Jensen ME, Camargo CA, Harvey SM, Gibson PG, Murphy VE, 'Serum 25 hydroxyvitamin d levels during pregnancy in women with asthma: Associations with maternal characteristics and adverse maternal and neonatal outcomes', Nutrients, 12 1-12 (2020)

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Low 25-hydroxyvitamin D (25(OH)D) levels are common in pregnancy and associated with adverse maternal/neonatal outcomes. ... [more]

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Low 25-hydroxyvitamin D (25(OH)D) levels are common in pregnancy and associated with adverse maternal/neonatal outcomes. In pregnant women with asthma, this study examined the association of lifestyle-and asthma-related factors on 25(OH)D levels and maternal/neonatal outcomes by vitamin D status. Serum 25(OH)D was measured at 16 and 35 weeks gestation in women with asthma (n = 103). Body mass index (BMI), gestational weight gain (GWG), smoking status, inhaled corticosteroid (ICS) use, asthma control, airway inflammation, and exacerbations, and maternal/neonatal outcomes were collected. Baseline and change (¿) in 25(OH)D were modelled separately using backward stepwise regression, adjusted for season and ethnicity. Maternal/neonatal outcomes were compared between low (25(OH)D < 75 nmol/L at both time points) and high (=75 nmol/L at one or both time points) vitamin D status. Fifty-six percent of women had low vitamin D status. Obesity was significantly associated with lower baseline 25(OH)D (Adj-R2 = 0.126, p = 0.008); ICS and airway inflammation were not. Excess GWG and season of baseline sample collection were significantly associated with ¿25(OH)D (Adj-R2 = 0.405, p < 0.0001); asthma-related variables were excluded (p > 0.2). Preeclampsia was more common in the low (8.6%) vs. high (0%) vitamin D group (p < 0.05). Obesity and excess GWG may be associated with gestational 25(OH)D levels, highlighting the importance of antenatal weight management.

DOI 10.3390/nu12102978
Co-authors Peter Gibson, Megan Jensen
2020 Harvey SM, Murphy VE, Gibson PG, Collison A, Robinson P, Sly PD, et al., 'Maternal asthma, breastfeeding, and respiratory outcomes in the first year of life', Pediatric Pulmonology, 55 1690-1696 (2020) [C1]

© 2020 Wiley Periodicals, Inc. Maternal asthma increases the risk of infant wheeze. Breastfeeding may offer protection but there is limited evidence in this high-risk group. We ex... [more]

© 2020 Wiley Periodicals, Inc. Maternal asthma increases the risk of infant wheeze. Breastfeeding may offer protection but there is limited evidence in this high-risk group. We examined associations between breastfeeding and respiratory outcomes, in infants born to women with asthma. This study was a secondary analysis of two prospective cohorts of pregnant women with asthma, and their infants, conducted between 2007 and 2018. At 6 ± 1 (T1) and 12 ± 1 (T2) months post-partum, mothers reported breastfeeding patterns and infant wheeze (primary outcome), bronchiolitis, and related medication use and healthcare utilization, via a validated questionnaire; a subgroup completed face-to-face interviews. ¿2 tests and logistic regression models, adjusting for confounders, were utilized. Data were complete for 605 participants at T1 and 486 (80%) at T2. Of 605 participants: 89% initiated breastfeeding and 38% breastfed for more than 6 months. Breastfeeding for more than 6 months vs ¿never¿ was associated with a reduced adjusted relative risk of infant wheeze at T1 (0.54, 95% confidence interval, 0.30-0.96). Bronchiolitis risk was reduced at T1 and T2 with more tha 6 months of breastfeeding vs ¿never.¿ Breastfeeding duration of 1 to 3 months, 4 to 6 months, and more than 6 months were associated with a reduced risk of infant healthcare utilization (all P <.05, vs ¿never¿), but not medication use (P >.05). Breastfeeding for more than 6 months was associated with a reduced risk of wheeze, bronchiolitis, and wheeze-related healthcare utilization in infants at risk due to maternal asthma. Notably, breastfeeding for shorter durations was associated with a reduced risk of healthcare utilization compared with none. Larger cohorts are needed to further examine the impact of breastfeeding exposure on respiratory health in infants exposed to maternal asthma.

DOI 10.1002/ppul.24756
Co-authors Joerg Mattes, Megan Jensen, Adam Collison, Peter Gibson
2020 McLaughlin K, Jensen ME, Foureur M, Gibson PG, Murphy VE, 'Fractional exhaled nitric oxide-based asthma management: The feasibility of its implementation into antenatal care in New South Wales, Australia', Australian and New Zealand Journal of Obstetrics and Gynaecology, 60 389-395 (2020) [C1]

© 2019 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists Background: The use of fractional exhaled nitric oxide (FeNO)-based asthma management durin... [more]

© 2019 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists Background: The use of fractional exhaled nitric oxide (FeNO)-based asthma management during pregnancy can significantly reduce asthma exacerbations in non-smoking pregnant women. The feasibility of implementing this strategy into antenatal care has not been explored. Aims: To examine the feasibility of implementing FeNO-based asthma management into antenatal clinics in New South Wales (NSW) Australia. Materials and Methods: Semi-structured face-to-face interviews with video elicitation were conducted with healthcare professionals (HCPs) providing antenatal care in one of two hospital-based antenatal clinics in NSW, Australia. The video shown demonstrated the use of the FeNO instrument and other aspects of the management strategy, in antenatal care. Interviews were recorded, transcribed and analysed using qualitative content analysis. Results: A total of 20 interviews were conducted with 15 midwives, four obstetricians, and one general practitioner. Two main themes and ten sub-themes arose: Getting a number (sub-themes: engaging, technically easy, objective, predictive, reassuring); and Resourcing (sub-themes: time and timing, systems, staff, education and cost). Comments included: ¿It's easy, fast and effective¿ and ¿the main barrier is time¿. All HCPs felt capable of facilitating the FeNO-based management strategy, with appropriate education, and were willing to undertake this strategy, saying: ¿¿it would be perfectly acceptable for a midwife or doctor to do it¿; also, ¿they don't necessarily need to see a physician, it's something that midwives would take on generally¿¿. Conclusion: Participants in this study considered FeNO-based asthma management for pregnant women to be a feasible addition to antenatal care following appropriate provision of resources and education.

DOI 10.1111/ajo.13061
Citations Web of Science - 1
Co-authors Maralyn Foureur, Karen Mclaughlin, Peter Gibson, Megan Jensen
2020 McLaughlin K, Jensen M, Foureur M, Murphy VE, 'Antenatal asthma management by midwives in Australia Self-reported knowledge, confidence and guideline use', Women and Birth, 33 e166-e175 (2020) [C1]

© 2019 Australian College of Midwives Background: Asthma affects approximately 12.7% of pregnant women in Australia. Increased maternal and infant morbidity is closely associated ... [more]

© 2019 Australian College of Midwives Background: Asthma affects approximately 12.7% of pregnant women in Australia. Increased maternal and infant morbidity is closely associated with poorly controlled asthma during pregnancy. Midwives are well placed to provide antenatal asthma management but data on current asthma management during pregnancy is not available, nor is the use of guidelines for clinical practice by this health professional group. Aim: To explore self-reported antenatal asthma management provided by midwives across Australia and how this reflects guideline recommendations. Method: An online survey was developed and distributed throughout Australia via the Australian College of Midwives, social media and healthcare facilities. Results: Responses from 371 midwives were obtained. Ten percent of midwives rated their knowledge as ¿good¿ and 1% as ¿very good¿, with 39% ¿poor¿ or ¿very poor¿. Being ¿somewhat¿ or ¿not at all¿ confident to provide antenatal asthma management was noted by 87% of midwives. Clinical guidelines were referred to by 50% of midwives and 40% stated that their main role was to refer women to other healthcare professionals. Only 54% reported that a clear referral pathway existed. Most respondents (>90%) recognised key recommendations for asthma management such as smoking cessation, appropriate vaccinations, and the continuation of prescribed asthma medications. Conclusion: Although midwives appear aware of key clinical recommendations for optimal antenatal asthma management, low referral to clinical practice guidelines and lack of knowledge and confidence was evident. Further research is required to determine what care pregnant women with asthma are actually receiving and identify strategies to improve antenatal asthma management by midwives.

DOI 10.1016/j.wombi.2019.04.007
Citations Scopus - 1Web of Science - 1
Co-authors Megan Jensen, Maralyn Foureur, Karen Mclaughlin
2020 McLaughlin K, Jensen ME, Foureur M, Gibson P, Murphy VE, 'The acceptability and feasibility of implementing a Fractional exhaled Nitric Oxide (FeNO)-based asthma management strategy into antenatal care: The perspective of pregnant women with asthma', Midwifery, 88 (2020) [C1]
DOI 10.1016/j.midw.2020.102757
Co-authors Karen Mclaughlin, Megan Jensen, Maralyn Foureur, Peter Gibson
2020 Murphy VE, Porsbjerg CM, Robijn AL, Gibson PG, 'Biomarker-guided management reduces exacerbations in non-eosinophilic asthma in pregnancy: A secondary analysis of a randomized controlled trial', Respirology, 25 719-725 (2020) [C1]

© 2019 Asian Pacific Society of Respirology Background and objective: The aim of this secondary analysis of a randomized controlled trial (RCT) of asthma management in pregnancy w... [more]

© 2019 Asian Pacific Society of Respirology Background and objective: The aim of this secondary analysis of a randomized controlled trial (RCT) of asthma management in pregnancy was to determine the treatment decision differences between a symptom control algorithm and a fractional exhaled nitric oxide (FENO)-guided algorithm, and whether the approach was effective in non-eosinophilic asthma (NEA). Methods: In this double-blind parallel group RCT, women with asthma were randomized prior to 22 weeks gestation to treatment adjustment according to a symptom control algorithm (control group), or a FENO-guided algorithm (inhaled corticosteroid (ICS) dose adjusted according to FENO with long-acting beta-agonist (LABA) added for uncontrolled symptoms). NEA was classified as baseline blood eosinophils <0.26 × 109/L and FENO =29 ppb. Exacerbations requiring medical intervention were recorded. Results: Among 220 non-smokers (n = 109 control, n = 111 FENO), 1006 treatment decisions were made, with significant group differences after the first and second algorithm applications. 53% of women had NEA. Treatment was better targeted to phenotype in the FENO group: ICS use increased in eosinophilic asthma (EA, 48¿86%), while ICS/LABA increased in NEA (11¿30%). Fewer women in the FENO group had exacerbations during pregnancy in NEA only (18.9% FENO vs 44% control, P = 0.006). Conclusion: The FENO algorithm was more effective in treating NEA, resulting in reduced exacerbations, compared to a symptom control algorithm. This was not the result of ICS overtreatment, since the benefits occurred at a lower median daily ICS dose. Two applications of the FENO-guided algorithm, one month apart, were sufficient to achieve beneficial effects in terms of asthma exacerbations, among pregnant women with asthma.

DOI 10.1111/resp.13713
Citations Scopus - 1Web of Science - 1
Co-authors Peter Gibson
2020 Robijn AL, Barker D, Gibson PG, Giles WB, Clifton VL, Mattes J, et al., 'Factors associated with non-adherence to inhaled corticosteroids for asthma during pregnancy.', The journal of allergy and clinical immunology. In practice, (2020)
DOI 10.1016/j.jaip.2020.09.045
Co-authors Peter Gibson, Daniel Barker, John Attia
2020 De Queiroz Andrade E, Da Silva Sena CR, Collison A, Murphy VE, Gould GS, Bonevski B, Mattes J, 'Association between active tobacco use during pregnancy and infant respiratory health: a systematic review and meta-analysis', BMJ open, 10 (2020) [C1]
DOI 10.1136/bmjopen-2020-037819
Co-authors Adam Collison, Gillian Gould, Joerg Mattes, Billie Bonevski
2020 Mallise CA, Lane AE, Woolard AJ, Whalen OM, Murphy VE, Karayanidis F, Campbell LE, 'The temperament features associated with autism spectrum disorder in childhood: A systematic review', Research in Developmental Disabilities, 104 (2020) [C1]
DOI 10.1016/j.ridd.2020.103711
Co-authors Linda E Campbell, Alix Woolard Uon, Alison Lane, Frini Karayanidis
2020 Jensen ME, Barrett HL, Peek MJ, Gibson PG, Murphy VE, 'Maternal asthma and gestational diabetes mellitus: Exploration of potential associations', Obstetric Medicine, (2020)

© The Author(s) 2020. Asthma and gestational diabetes mellitus are prevalent during pregnancy and associated with adverse perinatal outcomes. The risk of gestational diabetes mell... [more]

© The Author(s) 2020. Asthma and gestational diabetes mellitus are prevalent during pregnancy and associated with adverse perinatal outcomes. The risk of gestational diabetes mellitus is increased with asthma, and more severe asthma; yet, the underlying mechanisms are unknown. This review examines existing literature to explore possible links. Asthma and gestational diabetes mellitus are associated with obesity, excess gestational weight gain, altered adipokine levels and low vitamin D levels; yet, it¿s unclear if these underpin the gestational diabetes mellitus¿asthma association. Active antenatal asthma management reportedly mitigates asthma-associated gestational diabetes mellitus risk. However, mechanistic studies are lacking. Existing research suggests asthma management during pregnancy influences gestational diabetes mellitus risk; this may have important implications for future antenatal strategies to improve maternal-fetal outcomes by addressing both conditions. Addressing shared risk factors, as part of antenatal care, may also improve outcomes. Finally, mechanistic studies, to establish the underlying pathophysiology linking asthma and gestational diabetes mellitus, could uncover new treatment approaches to optimise maternal and child health outcomes.

DOI 10.1177/1753495X20926799
Co-authors Megan Jensen, Peter Gibson
2020 Whalen OM, Campbell LE, Murphy VE, Lane AE, Gibson PG, Mattes J, et al., 'Observational study of mental health in asthmatic women during the prenatal and postnatal periods', Journal of Asthma, 57 829-841 (2020) [C1]

© 2019, © 2019 Taylor &amp; Francis Group, LLC. Objective: We aimed to examine the prevalence and severity of psychological distress of women with asthma in both the prenatal an... [more]

© 2019, © 2019 Taylor & Francis Group, LLC. Objective: We aimed to examine the prevalence and severity of psychological distress of women with asthma in both the prenatal and postnatal periods, and to determine whether asthmatic women with and without mental health problems differ in self-management, medications knowledge, and asthma symptoms. Methods: We assessed spirometry performance and asthma symptoms in 120 women (mean age 29.8 years) before 23 weeks gestation, as part of the Breathing for Life Trial (Trial ID: ACTRN12613000202763). Prenatal depression data was obtained from medical records. At 6 weeks postpartum, we assessed general health, self-reported asthma control, depression symptoms (with the Edinburgh Postnatal Depression Scale) and adaptive functioning (with the Achenbach System of Empirically Based Assessment scales). Results: Twenty percent of our sample reported having a current mental health diagnosis, 14% reported currently receiving mental health care, while 47% reported having received mental health care in the past (and may/may not have received a diagnosis). The sample scored high on the Aggressive Behavior, Avoidant Personality, and Attention Deficit/Hyperactivity scales. Poorer self-reported postnatal asthma control was strongly correlated with elevated somatic complaints, externalizing problems, antisocial personality problems, and greater withdrawal. Prenatal spirometry or asthma severity and control were largely not associated with measures of psychopathology. Conclusions: These findings indicate that pregnant women with asthma frequently report issues with psychopathology during the prenatal and postnatal periods, and that the subjective perception of asthma control may be more related to psychopathology than objective asthma measures. However, due to sample bias, these findings are likely to be understated.

DOI 10.1080/02770903.2019.1621888
Co-authors Peter Gibson, Adam Collison, Alix Woolard Uon, Alison Lane, Frini Karayanidis, Linda E Campbell, Joerg Mattes
2020 de Gouveia Belinelo P, Nielsen A, Goddard B, Platt L, Da Silva Sena CR, Robinson PD, et al., 'Clinical and lung function outcomes in a cohort of children with severe asthma.', BMC Pulm Med, 20 66 (2020)
DOI 10.1186/s12890-020-1101-6
Co-authors Adam Collison, Joerg Mattes, Peter Gibson
2020 Murphy VE, Jensen ME, Robijn AL, Wright TK, Mattes J, Collison A, Gibson PG, 'How Maternal BMI Modifies the Impact of Personalized Asthma Management in Pregnancy', Journal of Allergy and Clinical Immunology: In Practice, 8 219-228.e3 (2020) [C1]

© 2019 American Academy of Allergy, Asthma &amp; Immunology Background: Maternal asthma is associated with perinatal complications and respiratory illness in offspring. Obesity ... [more]

© 2019 American Academy of Allergy, Asthma & Immunology Background: Maternal asthma is associated with perinatal complications and respiratory illness in offspring. Obesity increases asthma exacerbation risk in pregnancy and risk of wheeze in offspring. Objectives: In this secondary analysis of a randomized controlled trial, we investigated the influence of maternal body mass index, gestational weight gain (GWG), and fractional exhaled nitric oxide (FENO)-based management on asthma exacerbations in pregnancy and offspring wheeze. Methods: A total of 220 women were randomized to asthma treatment adjustment according to symptoms (control group), or FENO and symptoms (FENO group). Exacerbations were recorded prospectively. Height and weight were measured at baseline, and in late pregnancy. GWG was categorized according to Institute of Medicine guidelines. A validated parent-completed questionnaire assessed infant wheeze-related outcomes. Results: FENO-based management was associated with a significantly lower incidence rate ratio for maternal exacerbations in nonobese mothers (0.52, 95% confidence interval [CI], 0.31-0.88, P = .015, n = 129), and women with GWG within recommendations (0.35, 95% CI, 0.12-0.96, P = .042, n = 43), but not for obese mothers (0.59, 95% CI, 0.32-1.08, P = .089, n = 88), or women with excess GWG (0.58, 95% CI, 0.32-1.04, P = .07, n = 104). Recurrent bronchiolitis occurred in 5.3% (n = 1) of infants born to non-overweight mothers, 16.7% (n = 3) of infants of overweight mothers, and 21.7% (n = 5) of infants of obese mothers in the control group. In the FENO group, 2 infants of obese mothers had recurrent bronchiolitis (7.1%, P = .031). Conclusions: The benefits of FENO-based management are attenuated among obese mothers and those with excess GWG, indicating the importance of weight management in contributing to improved asthma management in pregnancy.

DOI 10.1016/j.jaip.2019.06.033
Citations Scopus - 1Web of Science - 1
Co-authors Megan Jensen, Joerg Mattes, Adam Collison, Peter Gibson
2019 Robijn AL, Jensen ME, McLaughlin K, Gibson PG, Murphy VE, 'Inhaled corticosteroid use during pregnancy among women with asthma: A systematic review and meta-analysis', Clinical and Experimental Allergy, 49 1403-1417 (2019) [C1]

© 2019 John Wiley &amp; Sons Ltd Background: Studies demonstrate the prescription rate for inhaled corticosteroids (ICS) decreases in early pregnancy, possibly increasing exacer... [more]

© 2019 John Wiley & Sons Ltd Background: Studies demonstrate the prescription rate for inhaled corticosteroids (ICS) decreases in early pregnancy, possibly increasing exacerbation risk. This could be related to non-adherence to prescribed asthma medication or medication cessation by the patient or doctor. ICS use during pregnancy has not previously been summarized in a systematic review. Objective: The aim of this systematic review and meta-analysis was to evaluate the use of ICS during pregnancy among asthmatic women, specifically: (1) the prevalence of use, (2) changes of use during pregnancy compared with pre-pregnancy and (3) medication adherence among ICS users. Methods: We systematically searched literature in Embase, MEDLINE, CINAL and Cochrane, using terms related to asthma, pregnancy and medication use. All English articles reporting ICS among pregnant women with asthma were included. Prevalence, changes in ICS use during pregnancy and ICS adherence were pooled using STATA (version 15.0, StataCorp USA). Results: A total of 4237 references were retrieved in the initial search. Screening and review led to the inclusion of 52 articles for one or more aims (Aim 1: N¿=¿45; Aim 2, N¿=¿13; and Aim 3, N¿=¿5). The pooled prevalence of ICS use during pregnancy was 41% (95%CI 36%-45%); 49% (95%CI 44%-55%) in Europe, 39% (95%CI 32%-47%) in Australia and 34% (95%CI 27%-41%) in North America. In eight prescription databases, ICS prescription rates lowered in the first trimester of pregnancy, compared with pre-pregnancy, increased in the second trimester and decreased in the third trimester. Five studies reported ICS adherence among pregnant women, using four measures of self-reported non-adherence. In two comparable studies, pooled ICS non-adherence was 40% (95%CI 36%-44%). Conclusions: The prevalence of ICS use among pregnant women with asthma is 41% and varies widely between countries and continents, and prescription rates for ICS change throughout pregnancy. More studies are needed to investigate ICS adherence during pregnancy in women with asthma.

DOI 10.1111/cea.13474
Citations Scopus - 1Web of Science - 1
Co-authors Megan Jensen, Karen Mclaughlin, Peter Gibson
2019 Jensen ME, Murphy VE, Gibson PG, Mattes J, Camargo CA, 'Vitamin D status in pregnant women with asthma and its association with adverse respiratory outcomes during infancy', Journal of Maternal-Fetal and Neonatal Medicine, 32 1820-1825 (2019) [C1]

© 2018, © 2018 Informa UK Limited, trading as Taylor &amp; Francis Group. Background: Vitamin D may influence pregnancy and infant outcomes, especially infant respiratory health... [more]

© 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group. Background: Vitamin D may influence pregnancy and infant outcomes, especially infant respiratory health. This study aimed to examine vitamin D status in pregnant women with asthma, and whether higher vitamin D levels are associated with fewer adverse respiratory outcomes in their infants. Methods: Pregnant women with asthma, recruited from John Hunter Hospital Newcastle Australia (latitude 33°S), had serum total 25-hydroxyvitamin-D (25(OH)D) measured at 16 and 35 weeks gestation. Infant respiratory outcomes were collected at 12 months by parent-report questionnaire. Mother¿infant dyads were grouped by serum 25(OH)D during pregnancy: 25(OH)D < 75 nmol/L (at both time-points) versus 25(OH)D = 75 nmol/L (at one or both time-points). Results: In 52 pregnant women with asthma, mean serum 25(OH)D levels were 61 (range 26¿110) nmol/L at 16 weeks, and 65 (range 32¿116) nmol/L at 35 weeks, gestation. Thirty-one (60%) women had 25(OH)D < 75 nmol/L at both time-points; 21 (40%) had 25(OH)D = 75 nmol/L at one or both time-points. Maternal 25(OH)D < 75 nmol/L during pregnancy was associated with a higher proportion of infants with ¿wheeze ever¿ at 12 months, compared with 25(OH)D = 75 nmol/L (71 versus 43%, p =.04). Infant acute-care presentations (45 versus 13%, p =.02) and oral corticosteroid use (26 versus 4%, p =.03) due to ¿asthma/wheezing¿ were higher in the maternal group with 25(OH)D < 75 nmol/L, versus =75 nmol/L. Conclusions: Most pregnant women with asthma had low vitamin D status, which persisted across gestation. Low maternal vitamin D status was associated with greater risk of adverse respiratory outcomes in their infants, a group at high risk of developing childhood asthma.

DOI 10.1080/14767058.2017.1419176
Citations Scopus - 3Web of Science - 3
Co-authors Peter Gibson, Joerg Mattes, Megan Jensen
2019 Robijn AL, Murphy VE, Gibson PG, 'Recent developments in asthma in pregnancy', Current Opinion in Pulmonary Medicine, 25 11-17 (2019) [C1]

© 2019 Lippincott Williams and Wilkins. All rights reserved. Purpose of reviewAsthma affects up to 13% of pregnancies worldwide and has a varying and unpredictable clinical course... [more]

© 2019 Lippincott Williams and Wilkins. All rights reserved. Purpose of reviewAsthma affects up to 13% of pregnancies worldwide and has a varying and unpredictable clinical course during pregnancy. Pharmacological asthma treatment is recommended; however, studies show that some pregnant women with asthma cease their medication in early pregnancy. There is likely a large unmet disease burden arising from asthma in pregnancy.Recent findingsAntenatal and asthma guidelines lack sufficient information on asthma management in pregnant women, and implementation of the current guidelines seems inadequate. Prescription databases provide evidence of cessation of asthma medication during pregnancy on a population level. Population-based databases also provide evidence of rare adverse perinatal outcomes. The risk of childhood asthma in the offspring of women with asthma is reduced by adequate control of maternal asthma during pregnancy. Vitamin D sufficiency during pregnancy could also reduce the risk of childhood asthma.SummaryThe findings of this review demonstrate the need for improved asthma and antenatal guidelines regarding asthma management during pregnancy, and the need of adequate implementation of these guidelines. Furthermore, adequate asthma control during pregnancy is needed to reduce the risk of childhood asthma. To maintain asthma control, prepregnancy medication should be continued throughout pregnancy and adjusted according to the current treatment steps if required.

DOI 10.1097/MCP.0000000000000538
Citations Scopus - 2Web of Science - 2
Co-authors Peter Gibson
2019 Whalen OM, Karayanidis F, Murphy VE, Lane AE, Mallise CA, Campbell LE, 'The effects of maternal asthma during pregnancy on child cognitive and behavioral development: A systematic review', Journal of Asthma, 56 130-141 (2019) [C1]

© 2018, © 2018 Taylor &amp; Francis Group, LLC. Objective: Maternal asthma during pregnancy is associated with a higher risk of negative perinatal outcomes. However, little is k... [more]

© 2018, © 2018 Taylor & Francis Group, LLC. Objective: Maternal asthma during pregnancy is associated with a higher risk of negative perinatal outcomes. However, little is known about the direct effects of maternal asthma on infant cognitive development. We examined the evidence for an impact of maternal asthma during pregnancy on cognitive and behavioral development of the child. Data sources: We conducted a MEDLINE, PsychINFO, and manual search of the databases for all available studies until January 9th, 2018. Study Selections: Studies were deemed relevant if they included child cognitive and behavioral development as the outcome, with maternal asthma as the determinant of interest. Results: Ten articles matched selection criteria. Some studies report that maternal asthma is associated with increased risk for autism and intellectual disability in children. However, these effects are small and are often eliminated when controlling for confounding variables. Other studies have found no association. The only prospective study found that well-managed asthma during pregnancy was not associated with negative developmental outcomes in children. Conclusions: The evidence suggests that the relationship between maternal asthma during pregnancy and poor developmental and behavioral outcomes of children is weak. Children of mothers with well-managed asthma during pregnancy have similar developmental trajectories to those born to healthy mothers. Prospective, longitudinal studies are needed to confirm these conclusions. Optimal asthma management is important in pregnancy as it may have longer term benefits for the health of the offspring. As the rate of asthma increases in the population, the implications of maternal asthma on child development will be of greater importance.

DOI 10.1080/02770903.2018.1437174
Citations Scopus - 1Web of Science - 2
Co-authors Frini Karayanidis, Linda E Campbell, Alison Lane
2019 Robijn AL, Jensen ME, Gibson PG, Powell H, Giles WB, Clifton VL, et al., 'Trends in asthma self-management skills and inhaled corticosteroid use during pregnancy and postpartum from 2004 to 2017.', The Journal of asthma : official journal of the Association for the Care of Asthma, 56 594-602 (2019) [C1]
DOI 10.1080/02770903.2018.1471709
Citations Scopus - 5Web of Science - 5
Co-authors Joerg Mattes, John Attia, Peter Wark, Peter Gibson, Megan Jensen
2019 Vanders RL, Hsu A, Gibson PG, Murphy VE, Wark PAB, 'Nasal epithelial cells to assess in vitro immune responses to respiratory virus infection in pregnant women with asthma', RESPIRATORY RESEARCH, 20 (2019) [C1]
DOI 10.1186/s12931-019-1225-5
Citations Web of Science - 1
Co-authors Peter Wark, Peter Gibson, Alan Hsu, Rebecca Vanders
2018 Morten M, Collison A, Murphy VE, Barker D, Oldmeadow C, Attia J, et al., 'Managing Asthma in Pregnancy (MAP) trial: FENO levels and childhood asthma', Journal of Allergy and Clinical Immunology, 142 1765-1772.e4 (2018) [C1]

© 2018 American Academy of Allergy, Asthma &amp; Immunology Background: The single-center double-blind, randomized controlled Managing Asthma in Pregnancy (MAP) trial in Newcast... [more]

© 2018 American Academy of Allergy, Asthma & Immunology Background: The single-center double-blind, randomized controlled Managing Asthma in Pregnancy (MAP) trial in Newcastle, Australia, compared a treatment algorithm using the fraction of exhaled nitric oxide (FENO) in combination with asthma symptoms (FENO group) against a treatment algorithm using clinical symptoms only (clinical group) in pregnant asthmatic women (Australian New Zealand Clinical Trials Registry, no. 12607000561482). The primary outcome was a 50% reduction in asthma exacerbations during pregnancy in the FENO group. However, the effect of FENO-guided management on the development of asthma in the offspring is unknown. Objective: We sought to investigate the effect of FENO-guided asthma management during pregnancy on asthma incidence in childhood. Methods: A total of 179 mothers consented to participate in the Growing into Asthma (GIA) double-blind follow-up study with the primary aim to determine the effect of FENO-guided asthma management on childhood asthma incidence. Results: A total of 140 children (78%) were followed up at 4 to 6 years of age. FENO-guided as compared to symptoms-only approach significantly reduced doctor-diagnosed asthma (25.9% vs 43.2%; odds ratio [OR], 0.46, 95% CI, 0.22-0.96; P =.04). Furthermore, frequent wheeze (OR, 0.27; 95% CI, 0.09-0.87; P =.03), use of short-acting ß-agonists (OR, 0.49; 95% CI, 0.25-0.97; P =.04), and emergency department visits for asthma (OR, 0.17; 95% CI, 0.04-0.76; P =.02) in the past 12 months were less common in children born to mothers from the FENO group. Doctor-diagnosed asthma was associated with common risk alleles for early onset asthma at gene locus 17q21 (P =.01 for rs8069176; P =.03 for rs8076131), and higher airways resistance (P =.02) and FENO levels (P =.03). A causal mediation analysis suggested natural indirect effects of FENO-guided asthma management on childhood asthma through ¿any use¿ and ¿time to first change in dose¿ of inhaled corticosteroids during the MAP trial (OR: 0.83; 95% CI: 0.59-0.99, and OR: 0.90; 95% CI: 0.70-1.03, respectively). Conclusions: FENO-guided asthma management during pregnancy prevented doctor-diagnosed asthma in the offspring at preschool age, in part mediated through changes in use and dosing of inhaled corticosteroids during the MAP trial.

DOI 10.1016/j.jaci.2018.02.039
Citations Scopus - 20Web of Science - 20
Co-authors John Attia, Daniel Barker, Peter Gibson, Joerg Mattes, Christopher Oldmeadow, Adam Collison
2018 McLaughlin K, Foureur M, Jensen ME, Murphy VE, 'Review and appraisal of guidelines for the management of asthma during pregnancy', Women and Birth, 31 e349-e357 (2018) [C1]

© 2018 Australian College of Midwives Background: Asthma affects 12.7% of pregnancies in Australia. Poorly controlled asthma is associated with increased maternal and infant morbi... [more]

© 2018 Australian College of Midwives Background: Asthma affects 12.7% of pregnancies in Australia. Poorly controlled asthma is associated with increased maternal and infant morbidity and mortality. Optimal antenatal management of asthma during pregnancy has the potential to reduce complications relating to asthma. Evidence-based clinical practice guidelines help to translate health research findings into practice and when implemented can improve health outcomes. National and International guidelines currently provide recommendations for optimal asthma care in pregnancy. Aim: To appraise the existing asthma in pregnancy guidelines with respect to their evidence for recommendations, consistency of recommendations and appropriateness for clinical practice. Method: The Appraisal of Guidelines for Research and Evaluation (AGREE II) tool was used to appraise four English language asthma in pregnancy guidelines, published or updated between 2007 and 2016. The recommendations, range and level of evidence was analysed. Results: Two of the four guidelines scored highly in most domains of the appraisal. Many of the recommendations made in the appraised guidelines were consistent. Due to the lack of randomised controlled trials involving pregnant women with asthma, most recommendations were evidenced by consensus and expert opinion rather than high quality meta-analysis, systematic reviews of randomised controlled trials. Conclusion: The recommended antenatal asthma management was generally consistent among the guidelines but lacked clarity in some areas which then leave them open to interpretation. More randomised controlled trials involving pregnant women with asthma are required to fortify the recommendations made and asthma management guidelines should be included in Australian Antenatal Care Guidelines as they currently are not.

DOI 10.1016/j.wombi.2018.01.008
Citations Scopus - 7Web of Science - 7
Co-authors Karen Mclaughlin, Megan Jensen, Maralyn Foureur
2017 Murphy VE, Jensen ME, Powell H, Gibson PG, 'Influence of Maternal Body Mass Index and Macrophage Activation on Asthma Exacerbations in Pregnancy', Journal of Allergy and Clinical Immunology: In Practice, 5 981-987.e1 (2017) [C1]

© 2017 American Academy of Allergy, Asthma &amp; Immunology Background Obesity is a risk factor for exacerbations of asthma, but the mechanisms of this effect in pregnancy are u... [more]

© 2017 American Academy of Allergy, Asthma & Immunology Background Obesity is a risk factor for exacerbations of asthma, but the mechanisms of this effect in pregnancy are unknown. Objective This study determined the influence of maternal body mass index, gestational weight gain, eosinophilic inflammation, and systemic macrophage activation on the risk of exacerbations during pregnancy. Methods Women with asthma (n = 164) participated in the study. Body mass index recorded at baseline (17 weeks gestation) was categorized as healthy weight (18.5-24.9 kg/m2), overweight (25-29.9 kg/m2), or obese (>30 kg/m2). Exacerbations requiring medical intervention were recorded prospectively. Asthma control, medication use, and fractional exhaled nitric oxide were assessed monthly; additional visits occurred during exacerbations. Peripheral blood was collected at baseline for the measurement of eosinophils, soluble CD-163, C-reactive protein, and IL-6. Results Exacerbations occurred in a higher proportion of overweight (51.1%) and obese (48.4%) women compared with healthy weight women (25%; P =.026). Excess weight gain during pregnancy was not associated with exacerbation risk. Macrophage activation (elevated serum soluble CD-163) was associated with exacerbations requiring oral corticosteroids (P =.043), whereas high peripheral blood eosinophils or fractional exhaled nitric oxide were not associated with exacerbation or oral corticosteroid use. Conclusions Being overweight or obese confers a greater risk of asthma exacerbation during pregnancy, and may be due to systemic macrophage activation.

DOI 10.1016/j.jaip.2017.03.040
Citations Scopus - 10Web of Science - 10
Co-authors Peter Gibson, Megan Jensen
2017 Murphy VE, Jensen ME, Gibson PG, 'Asthma during Pregnancy: Exacerbations, Management, and Health Outcomes for Mother and Infant', SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE, 38 160-173 (2017) [C1]
DOI 10.1055/s-0037-1600906
Citations Scopus - 13Web of Science - 11
Co-authors Peter Gibson, Megan Jensen
2016 Woolard A, Benders T, Campbell L, Karayanidis F, Mattes J, Murphy V, et al., 'Exploring the association of infant temperament on maternal fundamental frequency contours', Sixteenth Australasian International Conference on Speech Science and Technology, 229-232 (2016)
Co-authors Alison Lane, Alix Woolard Uon, Linda E Campbell, Frini Karayanidis, Joerg Mattes
2016 McLaughlin K, Kable A, Ebert L, Murphy V, 'Midwives' perception of their role in providing antenatal asthma management in Australia - A qualitative study', Midwifery, 35 11-16 (2016) [C1]

© 2016 Elsevier Ltd. International guidelines recommend a collaborative approach to the care of pregnant women with asthma. Midwives, as the primary health care provider for child... [more]

© 2016 Elsevier Ltd. International guidelines recommend a collaborative approach to the care of pregnant women with asthma. Midwives, as the primary health care provider for childbearing women should be viewed as collaborative partners in the provision of antenatal asthma management. However, the role of the midwife in providing antenatal asthma management has not been widely reported.Method: Australian midwives' perceived role in antenatal asthma management was studied using a qualitative descriptive method. Semi-structured in-depth interviews were conducted with 13 midwives working in a regional tertiary hospital. Morse and Field's four-stage process was used to analyse the data.Findings: the perceived role of the midwife in antenatal asthma management varied among participants. Some midwives stated their role was to refer women on to other health professionals. Other midwives stated that they should provide education to the women regarding their asthma management during their pregnancy.Conclusion: participants were uncertain about their role and lacked confidence in antenatal asthma management. The midwifery context in which they worked and the resources available to them at this health care facility appeared to influence the perception of their role.

DOI 10.1016/j.midw.2016.01.016
Citations Scopus - 10Web of Science - 9
Co-authors Lyn Ebert, Ashley Kable, Karen Mclaughlin
2016 Murphy VE, Jensen ME, Mattes J, Hensley MJ, Giles WB, Peek MJ, et al., 'The Breathing for Life Trial: a randomised controlled trial of fractional exhaled nitric oxide (FENO)-based management of asthma during pregnancy and its impact on perinatal outcomes and infant and childhood respiratory health', BMC PREGNANCY AND CHILDBIRTH, 16 (2016)
DOI 10.1186/s12884-016-0890-3
Citations Scopus - 17Web of Science - 16
Co-authors Joerg Mattes, John Attia, Megan Jensen, Michael Hensley, Peter Gibson, Andrew Searles
2015 Vanders RL, Murphy VE, 'Maternal complications and the management of asthma in pregnancy', Women's Health, 11 183-191 (2015) [C1]

© 2015 Future Medicine Ltd. Pregnancy is a unique state requiring alterations in maternal physiology to accommodate the growing fetus. Whilst the maternal immune system is normall... [more]

© 2015 Future Medicine Ltd. Pregnancy is a unique state requiring alterations in maternal physiology to accommodate the growing fetus. Whilst the maternal immune system is normally well adept at performing this task, the presence of immune disorders, such as asthma, often lead to pregnancy-related complications affecting both mother and baby. Australia has a high prevalence of asthma; with approximately 12% of pregnant women reported to have current asthma. Poor control of asthma is of far greater risk than the use of asthma medications. Being able to identify complications associated with asthma during pregnancy is of great importance in providing appropriate asthma management and medical care to these pregnant women, which may have lifelong consequences for their offspring.

DOI 10.2217/whe.14.69
Citations Scopus - 10Web of Science - 6
Co-authors Rebecca Vanders
2015 Thorburn AN, McKenzie CI, Shen S, Stanley D, MacIa L, Mason LJ, et al., 'Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites', Nature Communications, 6 (2015) [C1]

© 2015 Macmillan Publishers Limited. All rights reserved. Asthma is prevalent in Western countries, and recent explanations have evoked the actions of the gut microbiota. Here we ... [more]

© 2015 Macmillan Publishers Limited. All rights reserved. Asthma is prevalent in Western countries, and recent explanations have evoked the actions of the gut microbiota. Here we show that feeding mice a high-fibre diet yields a distinctive gut microbiota, which increases the levels of the short-chain fatty acid, acetate. High-fibre or acetate-feeding led to marked suppression of allergic airways disease (AAD, a model for human asthma), by enhancing T-regulatory cell numbers and function. Acetate increases acetylation at the Foxp3 promoter, likely through HDAC9 inhibition. Epigenetic effects of fibre/acetate in adult mice led us to examine the influence of maternal intake of fibre/acetate. High-fibre/acetate feeding of pregnant mice imparts on their adult offspring an inability to develop robust AAD. High fibre/acetate suppresses expression of certain genes in the mouse fetal lung linked to both human asthma and mouse AAD. Thus, diet acting on the gut microbiota profoundly influences airway responses, and may represent an approach to prevent asthma, including during pregnancy.

DOI 10.1038/ncomms8320
Citations Scopus - 316Web of Science - 300
Co-authors Joerg Mattes, Lisa Wood, Peter Gibson
2015 Murphy VE, 'Managing asthma in pregnancy', Breathe, 11 259-267 (2015) [C1]

Asthma is a common comorbidity during pregnancy and its prevalence is increasing in the com- munity. Exacerbations are a major clinical problem during pregnancy with up to 45% of ... [more]

Asthma is a common comorbidity during pregnancy and its prevalence is increasing in the com- munity. Exacerbations are a major clinical problem during pregnancy with up to 45% of women needing to seek medical help, resulting in poor outcomes for mothers and their babies, including low birth weight and preterm delivery. The goals of effective asthma management in pregnancy are to maintain the best possible asthma control and prevent exacerbations. This is achieved by aiming to prevent day- and night-time symptoms, and maintain lung function and normal activity. In addition, maintaining fetal oxygenation is an important consideration in pregnancy. Guide- lines recommend providing asthma advice and review prior to conception, and managing asthma actively during pregnancy, with regular 4-weekly review, provision of a written action plan, use of preventer medications as indicated for other adults with asthma, and management of comorbid conditions such as rhinitis. Improvements have been made in recent years in emergency department management of asthma in pregnancy, and multidisciplinary approaches are being proposed to optimise both asthma outcomes and perinatal outcomes. One strategy that has demonstrated success in reducing exacerbations in pregnancy is treatment adjustment using a marker of eosinophilic lung inflammation, the exhaled nitric oxide fraction (FeNO). The use of an algorithm that adjusted inhaled corticosteroids (ICS) according to FeNO and added long-acting ß-agonists when symptoms remained uncontrolled resulted in fewer exacerbations, more women on ICS but at lower mean doses, and improved infant respiratory health at 12 months of age. Further evidence is needed to determine whether this strategy can also improve perinatal outcomes and be successfully translated into clinical practice.

DOI 10.1183/20734735.007915
Citations Scopus - 19Web of Science - 16
2015 Vanders RL, Murphy VE, Gibson PG, Hansbro PM, Wark PAB, 'CD8 T cells and dendritic cells: Key players in the attenuated maternal immune response to influenza infection', Journal of Reproductive Immunology, 107 1-9 (2015) [C1]

© 2014 Elsevier Ireland Ltd. Pregnancy provides a unique challenge for maternal immunity, requiring the ability to tolerate the presence of a semi-allogeneic foetus, and yet still... [more]

© 2014 Elsevier Ireland Ltd. Pregnancy provides a unique challenge for maternal immunity, requiring the ability to tolerate the presence of a semi-allogeneic foetus, and yet still being capable of inducing an immune response against invading pathogens. To achieve this, numerous changes must occur in the activity and function of maternal immune cells throughout the course of pregnancy. Respiratory viruses take advantage of these changes, altering the sensitive balance of maternal immunity, leaving the mother with increased susceptibility to viral infections and increased disease severity. Influenza virus is one of the most common respiratory virus infections during pregnancy, leading to an increased risk of ICU hospitalisations, pneumonia, acute respiratory distress syndrome and even death. Whilst much research has been performed to understand the changes that must take place in maternal immunity during pregnancy, considerable work is still needed to fully comprehend this tremendous feat. To date, few studies have focused on the alterations that occur in maternal immunity during respiratory virus infections. This review highlights the role of dendritic cells (DCs) and CD8 T cells during pregnancy, and the changes that occur in these antiviral cells following influenza virus infections.

DOI 10.1016/j.jri.2014.09.051
Citations Scopus - 8Web of Science - 9
Co-authors Peter Gibson, Peter Wark, Rebecca Vanders, Philip Hansbro
2015 McLaughlin K, Kable A, Ebert L, Murphy VE, 'Barriers preventing Australian midwives from providing antenatal asthma management', British Journal of Midwifery, 23 116-123 (2015) [C1]

© 2015 MA Healthcare Ltd. International guidelines indicate that management of asthma during pregnancy should be multidisciplinary; however, the role of midwives has not been rese... [more]

© 2015 MA Healthcare Ltd. International guidelines indicate that management of asthma during pregnancy should be multidisciplinary; however, the role of midwives has not been researched. Method: A qualitative descriptive study exploring Australian midwives' current knowledge about asthma in pregnancy and their perceived role in antenatal asthma management was conducted, involving individual semi-structured in-depth interviews with 13 midwives in a tertiary referral hospital. Data were analysed using Morse and Field's four-stage process. Findings: Midwives identified barriers preventing them from providing antenatal asthma management, including: lack of knowledge about asthma in pregnancy; time constraints; women's knowledge about asthma in pregnancy; lack of a clear referral pathway; and lack of accessible asthma management equipment. Barriers were influenced by the institutional context in which the midwives worked. Conclusion: While participants identified barriers preventing them from providing recommended antenatal asthma management, they also suggested that improving their knowledge about asthma in pregnancy and developing a clear referral pathway may be beneficial.

DOI 10.12968/bjom.2015.23.2.116
Citations Scopus - 6
Co-authors Lyn Ebert, Karen Mclaughlin, Ashley Kable
2015 Powell H, Murphy VE, Hensley MJ, Giles W, Clifton VL, Gibson PG, 'Rhinitis in pregnant women with asthma is associated with poorer asthma control and quality of life', Journal of Asthma, (2015) [C1]

© 2015 Taylor &amp; Francis. Objective: To describe the pattern and severity of rhinitis in pregnancy and the impact rhinitis has on asthma control and quality of life (QoL) in pr... [more]

© 2015 Taylor & Francis. Objective: To describe the pattern and severity of rhinitis in pregnancy and the impact rhinitis has on asthma control and quality of life (QoL) in pregnant women with asthma. Methods: Two hundred and eighteen non-smoking pregnant women with asthma were participants in a randomised controlled trial of exhaled nitric oxide guided treatment adjustment. Rhinitis was assessed using a visual analogue scale (VAS) scored from 0 to 10 and classified as current (VAS¿>¿2.5), moderate/severe versus mild (VAS¿>¿6 vs <5), atopic versus non-atopic and pregnancy rhinitis. At baseline, women completed the 20-Item Sino-Nasal Outcome Test (SNOT20), asthma-specific (AQLQ-M) QoL questionnaires and the Six-Item Short-Form State Trait Anxiety Inventory (STAI-6). Asthma control was assessed using the asthma control questionnaire (ACQ). Perinatal outcomes were collected after delivery. Results: Current rhinitis was present in 142 (65%) women including 45 (20%) women who developed pregnancy rhinitis. Women with current rhinitis had higher scores for ACQ (p¿=¿0.004), SNOT20 (p¿<¿0.0001) and AQLQ-M (p¿<¿0.0001) compared to women with no rhinitis. Current rhinitis was associated with increased anxiety symptoms (p¿=¿0.002), rhinitis severity was associated with higher ACQ score (p¿=¿0.004) and atopic rhinitis was associated with poorer lung function (p¿=¿0.037). Rhinitis symptom severity improved significantly during gestation (p¿<¿0.0001). There was no impact on perinatal outcomes. Improved asthma control was associated with improvement in rhinitis. Conclusion: Rhinitis in pregnant women with asthma is common and associated with poorer asthma control, sino-nasal and asthma-specific QoL impairment and anxiety. In the context of active asthma management there was significant improvement in rhinitis symptoms and severity as pregnancy progressed.

DOI 10.3109/02770903.2015.1054403
Citations Scopus - 13Web of Science - 12
Co-authors Peter Gibson, Michael Hensley
2015 Burgess L, McCaffery K, Powell H, Murphy VE, Gibson PG, Turner RM, 'The influence of asthma control on psychosocial outcomes for pregnant women with asthma', Journal of Asthma, (2015) [C1]

© 2015 Taylor &amp; Francis. Objective: To investigate the relationship between asthma control and psychosocial outcomes in pregnant women with asthma. Methods: Secondary analysis... [more]

© 2015 Taylor & Francis. Objective: To investigate the relationship between asthma control and psychosocial outcomes in pregnant women with asthma. Methods: Secondary analysis (N¿=¿221) of a randomized controlled trial of treatment adjustments, based on fractional exhaled nitric oxide versus clinical guideline-based algorithms. Psychosocial variables included generic and asthma-specific quality of life (SF12, AQLQ-M), illness perceptions (BIPQ), perceived control (PCAQ), perceived risk of side effects (PRSE) and anxiety (STAI-6). Asthma control was defined as controlled (Asthma Control Questionnaire (ACQ7)¿=1.5 at randomization and end of study), improved (ACQ7¿>¿1.5 at randomization and =1.5 at end of study) and unimproved (ACQ7¿>1.5 at end of study). Regression models were fitted for each psychosocial measure at the end of the study, with adjustment for baseline values and smoking status, with predictor variable asthma control. Results: Women with unimproved asthma had poorer physical (SF12, p¿=¿0.012) and asthma-specific quality of life across all domains (AQLQ-M, p¿=¿0.012) compared to women with controlled asthma. They believed that they had less control over their asthma (PCAQ total p¿=¿0.014), had more symptoms and that their illness had a greater effect on their emotions and their lives in general (BIPQ identity, consequences, concern, emotional response p¿=¿0.015). Women with improved asthma control had significantly lower AQLQ-M breathlessness (p¿=¿0.048) and lower total scores (p¿=¿0.04) than women with controlled asthma. Conclusions: Pregnant women who are not able to get control of their asthma symptoms may experience worse quality of life and are likely to have more negative perceptions about their condition.

DOI 10.3109/02770903.2015.1038833
Citations Scopus - 4Web of Science - 3
Co-authors Peter Gibson
2015 Mandaliya PH, Morten M, Kumar R, James A, Deshpande A, Murphy VE, et al., 'Ventilation inhomogeneities in children with congenital thoracic malformations', BMC Pulmonary Medicine, 15 (2015) [C1]

© Morten et al.; licensee BioMed Central. Background: Congenital thoracic malformations (CTM) are rare lung lesions that are managed with surgical resection or active surveillance... [more]

© Morten et al.; licensee BioMed Central. Background: Congenital thoracic malformations (CTM) are rare lung lesions that are managed with surgical resection or active surveillance. Methods: Nitrogen lung clearance index (LCI), reactance and resistance (X5Hz and R5Hz), forced expiratory volume in 1 s and forced vital capacity (FEV1 and FVC) were prospectively measured in 10 children with CTM (mean age/SD: 7.6/1.3) who had undergone surgical resection in early life and in 17 healthy children (mean age/SD: 4.8/0.4). Total lung capacity (TLC) was also conducted in children older than 7 years of age with CTM (n = 8). Results: Mean LCI was 8.0 (95% CI 7.5 to 8.5) in the CTM group and 7.3 (95% CI 7.0 to 7.6) in healthy children (p = 0.016). Mean X5Hz was -0.44kPa/l/s (95% CI -0.58 to -0.31) in the CTM group and -0.31kPa/l/s (95% CI -0.35 to -0.27) in healthy children (p = 0.02). Mean Z score for X5Hz was -2.11 (95% CI -3.59 to -0.63) in the CTM group and -0.11 (95% CI -0.55 to 0.33) in healthy children (p = 0.0008). Mean FEV1 was 1.21 L (95% CI 0.97 to 1.45) in the CTM group and 1.02 L (95% CI 0.90 to 1.15) in healthy children (p = 0.22). Mean % predicted FEV1 was 83% (95% CI 74 to 92) in the CTM group and 97% (95% CI 87 to 107) in healthy children (p < 0.05). Mean % predicted TLC in CTM children was 121.3% (95% CI 88.45 to 154.1). Mean LCI was inversely correlated with height z-scores in the CTM group (rs = -0.88, p = 0.002) but not in healthy children (rs = 0.22, p = 0.4). Conclusions: Children with CTM have impaired lung function as demonstrated by the significant differences in LCI, reactance and FEV1 but not FVC, resistance and TLC. These findings may be of clinical relevance as ventilation inhomogeneities are closely correlated with somatic growth in this study.

DOI 10.1186/s12890-015-0023-1
Citations Scopus - 4Web of Science - 5
Co-authors Joerg Mattes, Peter Gibson, Aniruddh Deshpande
2014 Mattes J, Murphy VE, Powell H, Gibson PG, 'Prenatal origins of bronchiolitis: Protective effect of optimised asthma management during pregnancy', Thorax, 69 383-384 (2014) [C1]

Objective Maternal asthma is the most common chronic disease complicating pregnancy and is a risk factor for bronchiolitis in infancy. Recurrent episodes of bronchiolitis are stro... [more]

Objective Maternal asthma is the most common chronic disease complicating pregnancy and is a risk factor for bronchiolitis in infancy. Recurrent episodes of bronchiolitis are strongly associated with the development of childhood asthma. Methods We conducted a follow-up study of infants born to women with asthma who completed a double-blind randomised controlled trial during pregnancy. In this trial, pregnant women with asthma were assigned to treatment adjustment by an algorithm using clinical symptoms (clinical group) or the fraction of exhaled nitric oxide (FeNO group) and we showed that the FeNO group had significantly lower asthma exacerbation rates in pregnancy. Results 146 infants attended the 12-month follow-up visit. Infants born to mothers from the FeNO group were significantly less likely to have recurrent episodes of bronchiolitis in the first year of life (OR 0.08, 95% CI 0.01 to 0.62; p=0.016) as compared with the clinical group. Conclusions Optimised management of asthma during pregnancy may reduce recurrent episodes of bronchiolitis in infancy, which could potentially modulate the risk to develop or the severity of emerging childhood asthma.

DOI 10.1136/thoraxjnl-2013-203388
Citations Scopus - 29Web of Science - 25
Co-authors Peter Gibson, Joerg Mattes
2014 Murphy VE, Mattes J, Powell H, Baines KJ, Gibson PG, 'Respiratory viral infections in pregnant women with asthma are associated with wheezing in the first 12 months of life', Pediatric Allergy and Immunology, 25 151-158 (2014) [C1]

Background: There are few studies investigating the relationship between respiratory viral infection in pregnancy and asthma in the offspring, and none among mothers with asthma. ... [more]

Background: There are few studies investigating the relationship between respiratory viral infection in pregnancy and asthma in the offspring, and none among mothers with asthma. Infants of mothers with asthma are more likely to wheeze and have a higher risk of developing asthma than infants of non-asthmatic mothers. Methods: A prospective cohort study of viral infection in pregnancy was conducted between 2007 and 2009, and a subgroup of infants of mothers with asthma was followed up at 6 and 12 months of age. During common colds, nasal and throat swabs were collected from mothers and respiratory viruses detected by polymerase chain reaction. Respiratory health of infants was assessed by parent-completed questionnaire. Results: Twelve-month-old infants whose mothers had confirmed viral infections in pregnancy (n = 26) reported more frequent wheeze (40% had 4-12 wheeze attacks compared with 0%), sleep disturbed by wheeze (1 night per week or more in 60% vs. 11%), beta agonist treatment for wheeze (27% vs. 0%), prolonged colds (2 wk or longer 31% vs. 0%), more eczema (40% vs. 6.3%), and parent-perceived asthma (32% vs. 0%), compared with infants whose mothers had common colds without laboratory-confirmed viral infection (n = 16). Conclusions: This study demonstrates a relationship between maternal respiratory viral infection in pregnancy and wheezing illness in infants of mothers with asthma. Viral infections are the most common cause of asthma exacerbations in pregnancy, and infants of asthmatic mothers are at increased risk of asthma themselves. Further research is needed to elucidate the mechanisms involved. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

DOI 10.1111/pai.12156
Citations Scopus - 12Web of Science - 12
Co-authors Katherine Baines, Joerg Mattes, Peter Gibson
2014 Murphy VE, Schatz M, 'Asthma in pregnancy: A hit for two', European Respiratory Review, 23 64-68 (2014) [C1]

Asthma commonly occurs in pregnant females, and recent data have outlined the risks of adverse perinatal outcomes among this population. There is an increased risk of low birth we... [more]

Asthma commonly occurs in pregnant females, and recent data have outlined the risks of adverse perinatal outcomes among this population. There is an increased risk of low birth weight and small for gestational age, particularly among females with moderate-to-severe asthma and exacerbations during pregnancy. There is also an increased risk of preterm birth, especially with oral steroid use, a small but statistically significant increased risk of congenital malformations, particularly of cleft lip with or without cleft palate, and an increased risk of neonatal hospitalisation and death. Active management may reduce these risks, possibly through reductions in exacerbations. Additional reassuring data have been presented for asthma medication use, which support the benefits outweighing the risks of indicated asthma medication use in pregnancy. Viral infections are an important trigger of asthma exacerbations in pregnancy, and recent data provides possible immunological changes that may explain this. Poor medication adherence despite worsening asthma symptoms in pregnancy is a problem which continues to be demonstrated in the literature. Improving asthma control in pregnancy has the potential to improve not only the mother's health but also that of her child. © ERS 2014.

DOI 10.1183/09059180.00008313
Citations Scopus - 25Web of Science - 11
2014 Wark PAB, Murphy V, Mattes J, 'The interaction between mother and fetus and the development of allergic asthma', Expert Review of Respiratory Medicine, 8 57-66 (2014) [C1]

The rising prevalence of asthma and atopic disease in industrialized countries in the last 50 years has raised important questions about how and why the disease develops in suscep... [more]

The rising prevalence of asthma and atopic disease in industrialized countries in the last 50 years has raised important questions about how and why the disease develops in susceptible populations. Most asthma begins in childhood in association with allergic sensitization and the development of a TH2 phenotype. It is recognized that asthma arises in the context of a complex interaction between genetic factors and the evolving immune system of the infant and the environment to which it is exposed, which now includes its in utero exposure. Early life exposures that lead to allergen sensitization and airway damage, especially in the form of viral respiratory tract infections, may lead to disease induction that commence the process that leads in some to asthma. Asthma models and early life observations suggest that repeated exposure to allergens and viral infection perpetuate a state of chronic airway inflammation leading to a maladaptive innate immune response that fails to resolve, characterized by chronic airway inflammation, airway remodeling and airway hyperresponsiveness. This article will concentrate on the development of asthma in the context of early life and maternal influences, including the effect of asthma on both the fetus and the mother. © 2014 Informa UK Ltd.

DOI 10.1586/17476348.2014.848795
Citations Scopus - 10Web of Science - 11
Co-authors Joerg Mattes, Peter Wark
2014 Gunawardhana LP, Baines KJ, Mattes J, Murphy VE, Simpson JL, Gibson PG, 'Differential DNA methylation profiles of infants exposed to maternal asthma during pregnancy', Pediatric Pulmonology, 49 852-862 (2014) [C1]

Background Asthma is a complex disease that involves both genetic factors and environmental exposures. Aberrant epigenetic modifications, such as DNA methylation, may be important... [more]

Background Asthma is a complex disease that involves both genetic factors and environmental exposures. Aberrant epigenetic modifications, such as DNA methylation, may be important in asthma development. Fetal exposure to maternal asthma during critical periods of in utero development may lead to epigenetic alterations that predispose infants to a greater risk of developing asthma themselves. We investigated alterations in the DNA methylation profile of peripheral blood from infants exposed to maternal asthma during pregnancy. Methods Peripheral blood was collected from 12-month-old infants born to women with (n = 25) and without (n = 15) doctor diagnosed asthma during pregnancy. Genomic DNA was extracted, bisulfite converted, and hybridized to Infinium Methylation 27 arrays (Illumina), containing over27,000 CpGs from 14,495 genes. CpG loci in only autosomal genes were classified as differentially methylated at the 99% level (P < 0.01, |DiffScore| > 22 and delta beta >0.06). Results There were 70 CpG loci, corresponding to 67 genes that were significantly differentially methylated. Twelve CpG loci (11 genes) showed greater than 10% comparative difference in DNA methylation, including hyper-methylated loci of FAM181A, MRI1, PIWIL1, CHFR, DEFA1, MRPL28, AURKA, and hypo-methylated loci of NALP1L5, MAP8KIP3, ACAT2, and PM20D1 in maternal asthma. Methylation of MAPK8IP3 was significantly negatively correlated with maternal blood eosinophils (r = -0.38; P = 0.022), maternal eNO (r = -0.44; P = 0.005), and maternal serum total IgE (r = -0.39, P = 0.015). Methylation of AURKA negatively correlated with maternal hemoglobin (r = -0.43; P = 0.008), infants height (r = -0.51; P < 0.001) and weight (r = -0.36; P = 0.021). Methylation of PM20D1 was lower in infants born to mothers with asthma on inhaled corticosteroid treatment. Methylation of PM20D1 was lower and MRI1 was higher in infants born to atopic mothers without asthma. Conclusions In an Australian study population, exposure to maternal asthma during pregnancy is associated with differential methylation profiles of infants' peripheral blood DNA, which may act as risk factors for future asthma development. © 2013 Wiley Periodicals, Inc.

DOI 10.1002/ppul.22930
Citations Scopus - 31Web of Science - 29
Co-authors Peter Gibson, Jodie Simpson, Joerg Mattes, Katherine Baines
2014 Wang G, Murphy VE, Namazy J, Powell H, Schatz M, Chambers C, et al., 'The risk of maternal and placental complications in pregnant women with asthma: A systematic review and meta-analysis', Journal of Maternal-Fetal and Neonatal Medicine, 27 934-942 (2014) [C1]

Objective: To investigate if maternal asthma is associated with an increased risk of maternal and placental complications in pregnancy. Methods: Electronic databases were searched... [more]

Objective: To investigate if maternal asthma is associated with an increased risk of maternal and placental complications in pregnancy. Methods: Electronic databases were searched for the following terms: (asthma or wheeze) and (pregnan* or perinat* or obstet*). Cohort studies published between January 1975 and March 2012 were considered for inclusion. Forty publications met the inclusion criteria, reporting at least one maternal or placental complication in pregnant women with and without asthma. Relative risk (RR) with 95% confidence intervals (CIs) was calculated. Results: Maternal asthma was associated with a significantly increased risk of cesarean section (RR=1.31, 95%CI=[1.22-1.39]), gestational diabetes (RR=1.39, 95%CI=[1.17-1.66]), hemorrhage (antepartum: RR=1.25, 95%CI=[1.10-1.42]; postpartum: RR=1.29, 95%CI=[1.18-1.41]), placenta previa (RR=1.23, 95%CI=[1.07-1.40]), placental abruption (RR=1.29, 95%CI=[1.14-1.47]) and premature rupture of membranes (RR=1.21, 95%CI=1.07-1.37). Moderate to severe asthma significantly increased the risk of cesarean section (RR=1.19, 95%CI=[1.09-1.31]) and gestational diabetes (RR=1.19, 95%CI=[1.06-1.33]) compared to mild asthma. Bronchodilator use was associated with a significantly lowered risk of gestational diabetes (RR=0.64, 95%CI=[0.57-0.72]). Conclusions: Pregnant women with asthma are at increased risk of maternal and placental complications, and women with moderate/severe asthma may be at particular risk. Further studies are required to elucidate whether adequate control of asthma during pregnancy reduces these risks. © 2014 Informa UK Ltd. All rights reserved.

DOI 10.3109/14767058.2013.847080
Citations Scopus - 43Web of Science - 41
Co-authors John Attia, Peter Gibson
2013 Murphy VE, Powell H, Wark PAB, Gibson PG, 'A Prospective Study of Respiratory Viral Infection in Pregnant Women With and Without Asthma', CHEST, 144 420-427 (2013) [C1]
DOI 10.1378/chest.12-1956
Citations Scopus - 27Web of Science - 22
Co-authors Peter Gibson, Peter Wark
2013 Vanders RL, Gibson PG, Murphy VE, Wark PAB, 'Plasmacytoid Dendritic Cells and CD8 T Cells From PregnantWomen Show Altered Phenotype and Function Following H1N1/09 Infection', JOURNAL OF INFECTIOUS DISEASES, 208 1062-1070 (2013) [C1]
DOI 10.1093/infdis/jit296
Citations Scopus - 15Web of Science - 15
Co-authors Rebecca Vanders, Peter Gibson, Peter Wark
2013 Powell H, McCaffery K, Murphy VE, Hensley MJ, Clifton VL, Giles W, Gibson PG, 'Psychosocial Variables Are Related to Future Exacerbation Risk and Perinatal Outcomes in Pregnant Women with Asthma', JOURNAL OF ASTHMA, 50 383-389 (2013) [C1]
DOI 10.3109/02770903.2012.757777
Citations Scopus - 29Web of Science - 25
Co-authors Michael Hensley, Peter Gibson
2013 Namazy JA, Murphy VE, Powell H, Gibson PG, Chambers C, Schatz M, 'Effects of asthma severity, exacerbations and oral corticosteroids on perinatal outcomes', EUROPEAN RESPIRATORY JOURNAL, 41 1082-1090 (2013) [C1]
DOI 10.1183/09031936.00195111
Citations Scopus - 73Web of Science - 69
Co-authors Peter Gibson
2013 Vanders RL, Gibson PG, Wark PAB, Murphy VE, 'Alterations in inflammatory, antiviral and regulatory cytokine responses in peripheral blood mononuclear cells from pregnant women with asthma', RESPIROLOGY, 18 827-833 (2013) [C1]
DOI 10.1111/resp.12068
Citations Scopus - 13Web of Science - 13
Co-authors Rebecca Vanders, Peter Gibson, Peter Wark
2013 Murphy VE, Wang G, Namazy JA, Powell H, Gibson PG, Chambers C, Schatz M, 'The risk of congenital malformations, perinatal mortality and neonatal hospitalisation among pregnant women with asthma: a systematic review and meta-analysis', BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 120 812-822 (2013) [C1]
DOI 10.1111/1471-0528.12224
Citations Scopus - 75Web of Science - 65
Co-authors Peter Gibson
2013 Giles W, Murphy V, 'Asthma in pregnancy: a review', Obstetric Medicine: The Medicine of Pregnancy, 6 58-63 (2013) [D1]
DOI 10.1258/om.2012.120008
Citations Web of Science - 3
2012 Vanders RL, Wark PA, Murphy VE, Gibson PG, 'Pregnant women have attenuated innate interferon responses to 2009 pandemic influenza a virus subtype H1N1', Journal of Infectious Diseases, 206 646-653 (2012) [C1]
Citations Scopus - 37Web of Science - 40
Co-authors Rebecca Vanders, Peter Wark, Peter Gibson
2012 Vanders RL, Gibson PG, Murphy VE, Wark PAB, 'Impaired type I and III interferon response to rhinovirus infection during pregnancy and asthma', Thorax, 67 209-214 (2012) [C1]
DOI 10.1136/thoraxjnl-2011-200708
Citations Scopus - 46Web of Science - 43
Co-authors Peter Gibson, Rebecca Vanders, Peter Wark
2012 McLernon PC, Wood LG, Murphy VE, Hodyl NA, Clifton VL, 'Circulating antioxidant profile of pregnant women with asthma', Clinical Nutrition, 31 99-107 (2012) [C1]
Citations Scopus - 11Web of Science - 10
Co-authors Lisa Wood
2012 Murphy VE, Namazy JA, Powell H, Schatz M, Chambers C, Attia JR, Gibson PG, 'Severity of asthma in pregnancy affects perinatal outcomes - Authors' Reply', BJOG - An International Journal of Obstetrics and Gynaecology, 119 508-509 (2012) [C3]
DOI 10.1111/j.1471-0528.2011.03258.x
Citations Scopus - 1Web of Science - 1
Co-authors Peter Gibson, John Attia
2012 McLernon PC, Wood LG, Murphy VE, Hodyl NA, Clifton VL, 'Fatty acid profile of pregnant women with asthma', e-SPEN Journal, 7 e78-e85 (2012) [C1]
DOI 10.1016/j.clnme.2012.01.004
Co-authors Lisa Wood
2011 Powell GH, Murphy VE, Taylor DR, Hensley MJ, McCaffery K, Giles W, et al., 'Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: A double-blind, randomised controlled trial', The Lancet, 378 983-990 (2011) [C1]
DOI 10.1016/s0140-6736(11)60971-9
Citations Scopus - 204Web of Science - 188
Co-authors Michael Hensley, Peter Gibson
2011 Murphy VE, Gibson PG, 'Asthma in pregnancy', Clinics in Chest Medicine, 32 93-110 (2011) [C1]
Citations Scopus - 52Web of Science - 44
Co-authors Peter Gibson
2011 Powell H, McCaffery K, Murphy VE, Hensley MJ, Clifton VL, Giles WB, Gibson PG, 'Psychosocial outcomes are related to asthma control and quality of life in pregnant women with asthma', Journal of Asthma, 48 1032-1040 (2011) [C1]
DOI 10.3109/02770903.2011.631239
Citations Scopus - 37Web of Science - 38
Co-authors Michael Hensley, Peter Gibson
2011 Murphy VE, Namazy JA, Powell H, Schatz M, Chambers C, Attia JR, Gibson PG, 'A meta-analysis of adverse perinatal outcomes in women with asthma', BJOG: An International Journal of Obstetrics and Gynaecology, 118 1314-1323 (2011) [C1]
DOI 10.1111/j.1471-0528.2011.03055.x
Citations Scopus - 173Web of Science - 159
Co-authors John Attia, Peter Gibson
2010 Murphy VE, Clifton VL, Gibson PG, 'The effect of cigarette smoking on asthma control during exacerbations in pregnant women', Thorax, 65 739-744 (2010) [C1]
DOI 10.1136/thx.2009.124941
Citations Scopus - 56Web of Science - 52
Co-authors Peter Gibson
2010 Hodyl NA, Wyper HJ, Osei-Kumah A, Scott NM, Murphy VE, Gibson PG, et al., 'Sex-specific associations between cortisol and birth weight in pregnancies complicated by asthma are not due to differential glucocorticoid receptor expression', Thorax, 65 677-683 (2010) [C1]
DOI 10.1136/thx.2009.123091
Citations Scopus - 31Web of Science - 30
Co-authors Roger Smith, Peter Gibson
2010 Clifton VL, Hodyl NA, Murphy VE, Giles WB, Baxter RC, Smith R, 'Effect of maternal asthma, inhaled glucocorticoids and cigarette use during pregnancy on the newborn insulin-like growth factor axis', Growth Hormone and IGF Research, 20 39-48 (2010) [C1]
DOI 10.1016/j.ghir.2009.07.004
Citations Scopus - 33Web of Science - 30
Co-authors Roger Smith
2009 Scott NM, Hodyl NA, Murphy VE, Osei-Kumah A, Wyper H, Hodgson DM, et al., 'Placental cytokine expression covaries with maternal asthma severity and fetal sex', Journal of Immunology, 182 1411-1420 (2009) [C1]
Citations Scopus - 70Web of Science - 66
Co-authors Deborah Hodgson, Roger Smith
2008 Murphy VE, Gibson PG, 'Premenstrual asthma: Prevalence, cycle-to-cycle variability and relationship to oral contraceptive use and menstrual symptoms', Journal of Asthma, 45 696-704 (2008) [C1]
DOI 10.1080/02770900802207279
Citations Scopus - 28Web of Science - 27
Co-authors Peter Gibson
2008 Johnson RF, Rennie N, Murphy VE, Zakar T, Clifton VL, Smith R, 'Expression of glucocorticoid receptor messenger ribonucleic acid transcripts in the human placenta at term', Journal of Clinical Endocrinology & Metabolism, 93 4887-4893 (2008) [C1]
DOI 10.1210/jc.2008-1077
Citations Scopus - 27Web of Science - 26
Co-authors Roger Smith
2007 Murphy VE, Fittock RJ, Zarzycki PK, Delahunty MM, Smith R, Clifton VL, 'Metabolism of synthetic steroids by the human placenta', Placenta, 28 39-46 (2007) [C1]
DOI 10.1016/j.placenta.2005.12.010
Citations Scopus - 62Web of Science - 52
Co-authors Roger Smith
2006 Murphy VE, Clifton VL, Gibson PG, 'Asthma exacerbations during pregnancy: incidence and association with adverse pregnancy outcomes', Thorax, 61 169-176 (2006) [C1]
DOI 10.1136/thx.2005.049718
Citations Scopus - 227Web of Science - 207
Co-authors Peter Gibson
2006 Murphy VE, Smith R, Giles WB, Clifton VL, 'Endocrine regulation of human fetal growth: The role of the mother, placenta, and fetus', Endocrine Reviews, 27 141-169 (2006) [C1]
DOI 10.1210/er.2005-0011
Citations Scopus - 384Web of Science - 348
Co-authors Roger Smith
2006 Murphy VE, Johnson RF, Wang YC, Akinsanya K, Gibson PG, Smith R, Clifton VL, 'Proteomic study of plasma proteins in pregnant women with asthma', Respirology, 11 41-48 (2006) [C1]
DOI 10.1111/j.1440-1843.2006.00782.x
Citations Scopus - 21Web of Science - 20
Co-authors Roger Smith, Peter Gibson
2006 Clifton VL, Rennie N, Murphy VE, 'Effect of inhaled glucocorticoid treatment on placental 11 beta-hydroxysteroid dehydrogenase type 2 activity and neonatal birthweight in pregnancies complicated by asthma', Australian and New Zealand Journal of Obstetrics and Gynaecology, 46 136-140 (2006) [C1]
DOI 10.1111/j.1479-828X.2006.00543.x
Citations Scopus - 49Web of Science - 42
2005 Murphy VE, Gibson PG, Smith R, Clifton VL, 'Asthma during pregnancy: mechanisms and treatment implications', European Respiratory Journal, 25 731-750 (2005) [C1]
DOI 10.1183/09031936.05.00085704
Citations Scopus - 112Web of Science - 101
Co-authors Peter Gibson, Roger Smith
2005 Murphy VE, Gibson PG, Talbot PI, Kessell CG, Clifton VL, 'Asthma self-management skills and the use of asthma education during pregnancy', European Respiratory Journal, 26 435-441 (2005) [C1]
DOI 10.1183/09031936.05.00135604
Citations Scopus - 68Web of Science - 56
Co-authors Peter Gibson
2005 Murphy VE, Johnson RF, Wang Y-C, Akinsanya K, Gibson PG, Smith R, Clifton VL, 'The Effect of Maternal Asthma on Placental and Cord Blood Protein Profiles', Society for Gynecological Investigation Journal, 12 349-355 (2005) [C1]
DOI 10.1016/j.jsgi.2005.01.024
Citations Scopus - 20Web of Science - 20
Co-authors Roger Smith, Peter Gibson
2005 Murphy VE, Gibson PG, Talbot PI, Clifton VL, 'Severe asthma exacerbations during pregnancy', Obstetrics and Gynecology, 106 1046-1054 (2005) [C1]
Co-authors Peter Gibson
2004 Clifton VL, Murphy VE, 'Maternal Asthma as a Model for Examining Fetal Sex-specific Effects on Maternal Physiology and Placental Mechanisms that Regulate Human Fetal Growth', Placenta, 18 S45-S52 (2004) [C1]
DOI 10.1016/j.placenta.2004.01.004
Citations Scopus - 109Web of Science - 103
2004 Johnson R, Mitchell C, Murphy V, Zakar T, 'Proteomic analysis of proteins in the human amnion during late gestation and labor.', Reproductive Sciences, 11 (2004) [C1]
2003 Murphy VE, Clifton VL, 'Alterations in human placental 11 beta-hydroxysteroid dehydrogenase type 1 and 2 with gestational age and labour', Placenta, 24 739-744 (2003) [C1]
DOI 10.1016/S0143-4004(03)00103-6
Citations Scopus - 103Web of Science - 101
2003 Murphy VE, Gibson PG, Giles WB, Zakar T, Smith R, Bisits AM, et al., 'Maternal Asthma Is Associated with Reduced Female Fetal Growth', American Journal of Respiratory & Critical Care Medicine, 168 1317-1323 (2003) [C1]
DOI 10.1164/rccm.200303-374OC
Citations Scopus - 187Web of Science - 181
Co-authors Peter Gibson, Roger Smith
2002 Murphy VE, Zakar T, Smith R, Giles WB, Gibson PG, Clifton VL, 'Reduced 11 -Hydroxysteroid Dehydrogenase Type 2 Activity Is Associated with Decreased Birth Weight Centile in Pregnancies Complicated by Asthma', The Journal of Clinical Endocrinology & Metabolism, 87(4) 1660-1668 (2002) [C1]
Citations Scopus - 114Web of Science - 110
Co-authors Roger Smith, Peter Gibson
2001 Clifton VL, Gu Q, Murphy VE, Schwartz J, Madsen G, Smith R, 'Erratum: Localization and characterization of urocortin during human pregnancy (Placenta (2000) vol. 21 (782-788))', Placenta, 22 264 (2001)
DOI 10.1053/plac.2001.0632
Co-authors Roger Smith
2000 Clifton VL, Qing G, Murphy VE, Schwartz J, Madsen GM, Smith R, 'Localization and Characterization of Urocortin during Human Pregancy', Placenta, 21 782-788 (2000) [C1]
Citations Scopus - 45Web of Science - 42
Co-authors Roger Smith
Show 75 more journal articles

Conference (110 outputs)

Year Citation Altmetrics Link
2020 Robijn A, Brew B, Jensen M, Rejno G, Lundholm C, Almqvist C, Murphy V, 'ASTHMA EXACERBATIONS DURING PREGNANCY INCREASE RISK OF ADVERSE PERINATAL OUTCOMES', RESPIROLOGY (2020)
2019 Mclaughlin K, Foureur M, Jensen M, Gibson P, Murphy V, 'Stop, Start or Continue Asthma Medication in Pregnancy: Acceptability of a Biomarker-Based Approach to Antenatal Clinic Obstetricians and Midwives', AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY (2019)
Co-authors Karen Mclaughlin, Maralyn Foureur, Peter Gibson
2019 Murphy V, Gibson P, 'Stop, Start or Continue Asthma Medication: Use of a Biomarker-Based Approach for Adjusting Asthma Medication Dose During Pregnancy', AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY (2019)
Co-authors Peter Gibson
2019 Woolard A, Benders T, Campbell L, Karayanidis F, Murphy V, Lane S, et al., 'The relationship between pitch contours in infant-directed speech and infant risk for autism.', International Society for Autism Research Annual Meeting, Montreal, Canada. (2019)
Co-authors Frini Karayanidis, Linda E Campbell, Joerg Mattes, Alix Woolard Uon, Alison Lane
2019 Woolard A, Armstrong T, Benders T, Lane A, Karayanidis F, Murphy V, Campbell L, 'The relationship between maternal infant-directed speech and infant attention during the first year.', International Society for Autism Research Annual Meeting, Montreal, Canada (2019)
Co-authors Alison Lane, Alix Woolard Uon, Frini Karayanidis, Linda E Campbell
2019 Whalen O, Karayanidis F, Lane A, Murphy V, Campbell L, 'Investigating social cognition ability in infancy using a joint attention eye tracking paradigm.', Australian Society for Social and Affective Neuroscience Conference, Newcastle. (2019)
Co-authors Alison Lane, Linda E Campbell, Frini Karayanidis
2019 Mclaughlin K, Jensen M, Foureur M, Gibson P, Murphy V, 'Are pregnant women with asthma receiving guideline-recommended antenatal asthma management?- A survey of pregnant women in Australia', WOMEN AND BIRTH (2019)
DOI 10.1016/j.wombi.2019.07.207
Co-authors Peter Gibson, Karen Mclaughlin, Maralyn Foureur, Megan Jensen
2019 Mclaughlin K, Jensen M, Foureur M, Gibson P, Murphy V, 'The acceptability and feasibility of a novel asthma management strategy in Australian antenatal clinics-a qualitative descriptive study', WOMEN AND BIRTH (2019)
DOI 10.1016/j.wombi.2019.07.273
Co-authors Megan Jensen, Maralyn Foureur, Peter Gibson, Karen Mclaughlin
2019 Gomes GMC, Belinelo PG, Starkey MR, Jesson K, Loering S, Hansbro PM, et al., 'Unique subpopulations of cord blood innate lymphoid cells are associated with lung function at 6 weeks of age in babies born to mothers with asthma during pregnancy', ALLERGY, Lisbon, PORTUGAL (2019)
Co-authors Philip Hansbro, Peter Gibson, Malcolm Starkey, Adam Collison, Joerg Mattes
2019 Belinelo PDG, Jesson K, Appenzeller R, Gorlanova O, Collison A, Oldmeadow C, et al., 'Late Breaking Abstract - Maternal asthma, weight gain in early life and infant lung function', EUROPEAN RESPIRATORY JOURNAL, Madrid, SPAIN (2019)
DOI 10.1183/13993003.congress-2019.OA4937
Co-authors Joerg Mattes, Peter Gibson, Christopher Oldmeadow, Adam Collison
2019 Robijn A, Jensen M, Mclaughlin K, Gibson P, Murphy V, 'Evaluating inhaled corticosteroid use among pregnant women with asthma: systematic review and meta-analysis', EUROPEAN RESPIRATORY JOURNAL, Madrid, SPAIN (2019)
DOI 10.1183/13993003.congress-2019.PA2558
Citations Web of Science - 1
Co-authors Megan Jensen, Peter Gibson, Karen Mclaughlin
2019 McLaughlin K, Jensen M, Foureur M, Gibson P, Murphy V, 'The acceptibility and feasibility of FeNo-based asthma management in Australian antenatal clinics- A qualitative descriptive study', EUROPEAN RESPIRATORY JOURNAL, Madrid, SPAIN (2019)
DOI 10.1183/13993003.congress-2019.PA2624
Co-authors Karen Mclaughlin, Megan Jensen, Peter Gibson, Maralyn Foureur
2019 Jensen M, Robijn A, Gibson P, Oldmeadow C, Murphy V, 'The impact of gestation, and its interaction with asthma, on spirometry indices: a longitudinal analysis of lung function in pregnant women with and without asthma', EUROPEAN RESPIRATORY JOURNAL, Madrid, SPAIN (2019)
DOI 10.1183/13993003.congress-2019.PA2711
Co-authors Megan Jensen, Christopher Oldmeadow, Peter Gibson
2019 Andrade EDQY, Murphy V, Belinelo PDG, Jesson K, Collison A, Robinson P, et al., 'Prematurity and respiratory function at 6 weeks of age in infants born to mothers with asthma during pregnancy and active tobacco smoking', EUROPEAN RESPIRATORY JOURNAL, Madrid, SPAIN (2019)
DOI 10.1183/13993003.congress-2019.PA309
Co-authors Joerg Mattes, Peter Gibson, Adam Collison
2019 Robijn A, Jensen M, Gibson P, Murphy V, 'Factors associated with ICS non-adherence in pregnant women with asthma: a cross-sectional analysis', EUROPEAN RESPIRATORY JOURNAL, Madrid, SPAIN (2019)
DOI 10.1183/13993003.congress-2019.PA4185
Co-authors Megan Jensen, Peter Gibson
2019 Harvey S, Murphy V, Gibson P, Mattes J, Collison A, Jensen M, 'The association between breastfeeding and respiratory health in infants born to women with asthma: a secondary analysis of two cohort studies', EUROPEAN RESPIRATORY JOURNAL, Madrid, SPAIN (2019)
DOI 10.1183/13993003.congress-2019.PA5003
Citations Web of Science - 1
Co-authors Adam Collison, Megan Jensen, Joerg Mattes, Peter Gibson
2019 Murphy VE, Jensen M, Robijn A, Wright T, Mattes J, Collison A, Gibson P, 'Influence of maternal body mass index and gestational weight gain, with asthma management on maternal and infant outcomes', EUROPEAN RESPIRATORY JOURNAL, Madrid, SPAIN (2019)
DOI 10.1183/13993003.congress-2019.PA5026
Co-authors Megan Jensen, Joerg Mattes, Peter Gibson, Adam Collison
2019 McLaughlin K, Jensen M, Foureur M, Gibson P, Murphy V, 'A survey of pregnant women with asthma in Australia-Are they receiving guideline recommendations?', EUROPEAN RESPIRATORY JOURNAL, Madrid, SPAIN (2019)
DOI 10.1183/13993003.congress-2019.PA5030
Co-authors Peter Gibson, Megan Jensen, Maralyn Foureur, Karen Mclaughlin
2019 Robijn A, Jensen M, McLaughlin K, Gibson P, Murphy V, 'EVALUATING INHALED CORTICOSTEROID USE AMONG PREGNANT WOMEN WITH ASTHMA', RESPIROLOGY (2019)
Co-authors Karen Mclaughlin, Megan Jensen, Peter Gibson
2019 Mclaughlin K, Jensen M, Foureur M, Gibson P, Murphy V, 'KNOWLEDGE AND CONFIDENCE OF HEALTH PROFESSIONALS IN PROVIDING ASTHMA MANAGEMENT IN PREGNANCY: RESULTS OF AN AUSTRALIAN NATIONWIDE SURVEY', RESPIROLOGY (2019)
Co-authors Peter Gibson, Karen Mclaughlin, Maralyn Foureur
2019 Robijn AL, Jensen ME, Gibson PG, Murphy VE, 'Factors associated with inhaled corticosteroid non-adherence in pregnant women with asthma: a cross-sectional analysis', PHARMACOEPIDEMIOLOGY AND DRUG SAFETY (2019)
Co-authors Megan Jensen, Peter Gibson
2018 Woolard A, Benders T, Armstrong T, Karayanidis F, Murphy V, Mallise C, et al., 'The relationship between infant temperament and behaviour, and maternal infant-directed speech.', World Association for Infant Mental Health Conference, Rome, Italy. (2018)
Co-authors Linda E Campbell, Frini Karayanidis, Alix Woolard Uon, Alison Lane
2018 Woolard A, Benders T, Karayanidis F, Murphy VE, Mallise C, Whalen O, et al., 'The Characteristics of F0 Contours in Speech Directed at Infants at-Risk for Autism.', International Society for Autism Research Annual Meeting, Rotterdam, Netherlands. (2018)
Co-authors Frini Karayanidis, Linda E Campbell, Alix Woolard Uon, Alison Lane
2018 Whalen O, Karayanidis F, Lane A, Murphy V, Campbell L, 'The effectiveness of a joint attention eye tracking paradigm in measuring social cognition in the first year of life', Australian Society for Social and Affective Neuroscience, Brisbane. (2018)
Co-authors Linda E Campbell, Alison Lane, Frini Karayanidis
2018 Mallise C, Lane A, Karayanidis F, Murphy V, Woolard A, Whalen O, Campbell L, 'The Trajectory of Maternal Parenting Stress and Infant Temperament across the First Year of Life.', World Association for Infant Mental Health Conference, Rome, Italy. (2018)
Co-authors Frini Karayanidis, Linda E Campbell, Alix Woolard Uon, Alison Lane
2018 Gomes GMC, Belinelo PDG, Malcolm RS, Jesson K, Phil MH, Vanessa EM, et al., 'Cord blood eosinophils and Type 2 Innate lymphoid cells are correlated in infants born to mothers with asthma during pregnancy', EUROPEAN RESPIRATORY JOURNAL, Paris, FRANCE (2018)
DOI 10.1183/13993003.congress-2018.PA5433
Co-authors Malcolm Starkey, Peter Gibson, Joerg Mattes, Adam Collison, Philip Hansbro
2018 Lane A, Campbell L, Gibson P, Woolard A, Barker D, Tait J, et al., 'Early signs of autism in 12 month infants born to mothers with asthma', Griffith University, Gold Coast (2018)
Co-authors Joerg Mattes, Alison Lane, Alix Woolard Uon, Frini Karayanidis, Adam Collison, Linda E Campbell, Peter Gibson
2018 Murphy VE, Powell H, Porsbjerg C, Gibson P, 'Treatment decisions with an exhaled nitric oxide (eNO)-based algorithm vs a symptoms-based algorithm for asthma in pregnancy', EUROPEAN RESPIRATORY JOURNAL, Paris, FRANCE (2018)
DOI 10.1183/13993003.congress-2018.PA5042
Co-authors Peter Gibson
2018 Beinelo DGP, Jesson K, Sena SC, Collison A, Murphy V, Robinson P D, et al., 'LUNG FUNCTION AT 6 WEEKS OF AGE IS ASSOCIATED WITH THE RISK OF DEVELOPING BRONCHIOLITIS IN INFANTS BORN TO MOTHERS WITH ASTHMA DURING PREGNANCY', RESPIROLOGY (2018)
Co-authors Joerg Mattes, Adam Collison, Peter Gibson
2018 Jesson K, Belinelo DGP, Sena C RS, Collison A, Murphy V, Robinson P, et al., 'PREMATURITY, LUNG FUNCTION AT 6 WEEKS OF AGE AND BRONCHIOLITIS IN BABIES BORN TO MOTHERS WITH ASTHMA DURING PREGNANCY', RESPIROLOGY (2018)
Co-authors Joerg Mattes, Adam Collison, Peter Gibson
2018 Murphy VE, Metcalfe TB, Robijn A, Gibson PG, McCaffery K, Jensen ME, 'BELIEFS ABOUT MEDICINES AND ADHERENCE TO ASTHMA MEDICATION IN PREGNANCY', RESPIROLOGY (2018)
Co-authors Megan Jensen, Peter Gibson
2018 Robijn A, Jensen M, Gibson P, Murphy V, 'ASTHMA SELF-MANAGEMENT EDUCATION AND PERCEIVED ASTHMA MEDICATION RISK DURING PREGNANCY', RESPIROLOGY (2018)
Co-authors Peter Gibson
2018 Gomes G, Starkey M, Belinelo DGP, Jesson K, Hansbro P, Murphy V, et al., 'PROFILING INNATE LYMPHOID CELLS IN THE CORD BLOOD OF INFANTS BORN TO MOTHERS WITH ASTHMA IN PREGNANCY', RESPIROLOGY (2018)
Co-authors Joerg Mattes, Peter Gibson, Adam Collison, Philip Hansbro
2018 Whalen O, Karayanidis F, Lane A, Murphy V, Campbell L, 'The effectiveness of a joint attention eye tracking paradigm in measuring social cognition in the first year of life', Brisbane, Australia (2018)
Co-authors Linda E Campbell, Alison Lane, Frini Karayanidis
2017 Woolard A, Benders T, Campbell L, Karayanidis F, Murphy V, Mallise C, et al., 'The Effect of Infant Temperament on Maternal Infant-Directed Speech.', Lancaster Conference on Infant and Child Development, Lancaster, England. (2017)
Co-authors Frini Karayanidis, Linda E Campbell, Alison Lane, Alix Woolard Uon
2017 Morten M, Collison A, Murphy V, Barker D, Meredith J, Powell H, et al., 'ASTHMA CONTROL DURING PREGNANCY, 17Q21 VARIANTS AND CHILDHOOD-ONSET ASTHMA', RESPIROLOGY (2017)
Citations Web of Science - 1
Co-authors Daniel Barker, Adam Collison, Peter Gibson, Joerg Mattes
2017 McLaughlin K, McCaffery K, Foureur M, Murphy V, 'REVIEW OF ASTHMA IN PREGNANCY GUIDELINES', RESPIROLOGY (2017)
Citations Web of Science - 1
Co-authors Karen Mclaughlin, Maralyn Foureur
2017 Murphy V, Whalen O, Karayanidis F, Lane A, Campbell L, 'THE MENTAL HEALTH CHARACTERISTICS OF WOMEN WITH ASTHMA IN THE ANTENATAL AND POSTNATAL PERIOD', RESPIROLOGY (2017)
Co-authors Frini Karayanidis, Linda E Campbell, Alison Lane
2016 Jensen ME, Camargo CA, Gibson PG, Mattes J, Murphy VE, 'Maternal Serum Ditamin D Levels \= 75nmol/l During Pregnancy Are Associated With Fewer Adverse Respiratory Outcomes In Infants At 12 Months Of Age', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, San Francisco, CA (2016)
Co-authors Joerg Mattes, Peter Gibson, Megan Jensen
2016 Steel K, Gibson P, Murphy V, 'ASTHMA SELF-MANAGEMENT EDUCATION AND INHALED CORTICOSTEROID USE DURING PREGNANCY AND POSTPARTUM FROM 2004 TO 2014', RESPIROLOGY (2016)
Co-authors Peter Gibson
2016 Jensen M, Murphy V, Mattes J, Gibson P, Carmargo JC, 'MATERNAL SERUM VITAMIN D LEVELS \= 75 NMOL/L DURING PREGNANCY ARE ASSOCIATED WITH FEWER ADVERSE RESPIRATORY OUTCOMES IN INFANTS AT 12 MONTHS OF AGE', RESPIROLOGY (2016)
Co-authors Joerg Mattes, Peter Gibson
2016 Murphy V, Gibson PG, Collison A, Sly P, Czovek D, Robinson P, et al., 'Follow-up of infants from the Breathing for Life Trial BLT Babies and BLT-Infant Development.', Perinatal Society IMPACT Workshop, Townsville. (2016)
Co-authors Frini Karayanidis, Alison Lane, Joerg Mattes, Linda E Campbell
2016 Murphy V, Gibson P, 'THE USE OF FRACTIONAL EXHALED NITRIC OXIDE-BASED MANAGEMENT FOR NON-EOSINOPHILIC ASTHMA DURING PREGNANCY', RESPIROLOGY (2016)
Co-authors Peter Gibson
2016 Mclaughlin K, Kable A, Ebert L, Murphy V, 'MIDWIVES' PERCEPTION OF THEIR ROLE IN PROVIDING ANTENATAL ASTHMA MANAGEMENT IN AUSTRALIA-A QUALITATIVE STUDY', RESPIROLOGY (2016)
Co-authors Ashley Kable, Karen Mclaughlin, Lyn Ebert
2016 Woolard A, Benders T, Campbell L, Karayanidis F, Mattes J, Murphy V, et al., 'Exploring the association of infant temperament on maternal fundamental frequency contours.', Proceedings of the Sixteenth Australasian International Conference on Speech Science and Technology, University of Western Sydney, Parramatta (2016)
Co-authors Linda E Campbell, Frini Karayanidis, Alix Woolard Uon, Alison Lane, Joerg Mattes
2016 Murphy VE, Gibson PG, 'The Use Of Fractional Exhaled Nitric Oxide-Based Management For Non-Eosinophilic Asthma During Pregnancy', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, San Francisco, CA (2016)
Co-authors Peter Gibson
2015 Murphy VE, Powell H, Gibson P, 'Exacerbations Following Step Down And Step Up Inhaled Corticosteroid Therapy In The Managing Asthma In Pregnancy (map) Study', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Denver, CO (2015)
Co-authors Peter Gibson
2015 Murphy V, Powell H, Gibson P, 'EXACERBATIONS FOLLOWING STEP DOWN AND STEP UP INHALED CORTICOSTEROID THERAPY IN THE MANAGING ASTHMA IN PREGNANCY (MAP) STUDY', RESPIROLOGY, Queensland, AUSTRALIA (2015) [E3]
Citations Web of Science - 1
Co-authors Peter Gibson
2014 Murphy V, Powell H, Gibson P, 'THE ROLE OF MATERNAL OBESITY IN SUSCEPTIBILITY TO RESPIRATORY VIRAL INFECTION AND EXACERBATION RATE IN PREGNANT WOMEN WITH ASTHMA', RESPIROLOGY (2014)
Co-authors Peter Gibson
2013 Mattes J, Murphy V, Powell H, Gibson P, 'THE EFFECT OF BETTER ASTHMA CONTROL IN PREGNANCY ON WHEEZY ILLNESSES IN INFANCY', RESPIROLOGY (2013) [E3]
Citations Web of Science - 2
Co-authors Joerg Mattes, Peter Gibson
2013 Forbes RL, Gibson PG, Murphy VE, Wark PA, 'H1N1PDM09 ALTERS MATERNAL IMMUNITY DURING PREGNANCY', RESPIROLOGY (2013) [E3]
Co-authors Peter Wark, Peter Gibson
2013 Gunawardhana LP, Baines KJ, Mattes J, Murphy VE, Simpson JL, Gibson PG, 'EPIGENETIC ALTERATIONS IN INFANTS ASSOCIATED WITH MATERNAL ASTHMA DURING PREGNANCY', RESPIROLOGY (2013) [E3]
Co-authors Joerg Mattes, Katherine Baines, Peter Gibson, Jodie Simpson
2012 Powell HG, McCaffery K, Murphy VE, Giles W, Clifton VL, Hensley MJ, Gibson PG, 'Psychosocial outcomes are related to future exacerbation risk and perinatal outcomes in pregnant women with asthma', Respirology, Canberra, ACT (2012) [E3]
Citations Web of Science - 1
Co-authors Michael Hensley, Peter Gibson
2011 Clifton VL, McLernon PC, Wood LG, Murphy VE, Stark MJ, Hodyl NA, 'What do women eat during pregnancy?', Journal of Developmental Origins of Health and Disease, Portland, Oregon (2011) [E3]
Co-authors Lisa Wood
2011 Namazy JA, Murphy VE, Powell H, Gibson PG, Chambers C, Schatz M, 'Effects of asthma severity and medication use on prematurity and intrauterine growth: A meta analysis from published data', Journal of Allergy and Clinical Immunology, San Francisco, CA (2011) [E3]
Co-authors Peter Gibson
2011 Clifton V, McLernon P, Wood LG, Murphy VE, Hodyl N, 'What do pregnant women eat?', Placenta: Abstracts of the IFPA Meeting 2011, Geilo, Norway (2011) [E3]
Co-authors Lisa Wood
2011 Gibson PG, Powell H, Giles W, Clifton V, Hensley MJ, Taylor DR, et al., 'Asthma exacerbations during pregnancy are reduced by inflammometry (FENO) guided asthma management: A randomised controlled trial', American Journal of Respiratory and Critical Care Medicine, Denver, CO (2011) [E3]
Co-authors Peter Gibson, Michael Hensley
2011 McLaughlin KM, Mattes J, Murphy VE, Steel KR, Powell H, Gibson PG, 'The Growing Into Asthma (GIA) Study: Need for improved management of respiratory illnesses in early life', PSANZ 2011 15th Annual Congress: Poster Abstracts, Hobart, TAS (2011) [E3]
Co-authors Joerg Mattes, Karen Mclaughlin, Peter Gibson
2011 Vanders RL, Gibson PG, Murphy VE, Wark PA, 'Reduced antiviral interferons during pregnancy explains susceptibility to influenza virus infection', Respirology, Perth, WA (2011) [E3]
Co-authors Peter Gibson, Rebecca Vanders, Peter Wark
2011 Gunawardhana LP, Baines KJ, Simpson JL, Mattes J, Murphy VE, Gibson PG, 'Maternal asthma is associated with alterations in DNA methylation profile of peripheral blood of infants', Respirology, Perth, WA (2011) [E3]
Co-authors Katherine Baines, Jodie Simpson, Joerg Mattes, Peter Gibson
2011 Mattes J, Murphy VE, McLaughlin KM, Steel KR, Powell H, Gibson PG, 'Are maternal asthma exacerbations during pregnancy related to impaired infant growth in the first six months of life?', Respirology, Perth, WA (2011) [E3]
Co-authors Joerg Mattes, Karen Mclaughlin, Peter Gibson
2010 Murphy VE, Namazy JA, Powell GH, Gibson PG, Chambers C, Attia JR, Schatz M, 'A meta-analysis of adverse perinatal outcomes in asthmatic women: Effect of asthma on placental and neonatal outcomes', American Journal of Respiratory and Critical Care Medicine, New Orleans (2010) [E3]
Co-authors John Attia, Peter Gibson
2010 Namazy JA, Murphy VE, Powell HG, Gibson PG, Chambers CD, Schatz M, 'Congenital anomalies in asthmatic women using corticosteroids during pregnancy: A meta analysis from published data', Birth Defects Research (Part A), Louisville, KT (2010) [E3]
Co-authors Peter Gibson
2010 McLernon PC, Murphy VE, Wood LG, Dekker GA, Hodyl NA, Clifton VL, 'Maternal plasma circulating levels of omega (n)3 long chain polyunsaturated fatty acids, eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA) are associated with fetal growth measures', The Endocrine Society of Australia Annual Scientific Meeting Proceedings and Abstract Book, Sydney (2010) [E3]
Co-authors Lisa Wood
2010 Namazy JA, Murphy VE, Powell HG, Gibson PG, Chambers C, Schatz M, 'Adverse perinatal outcomes in asthmatic women: A meta analysis from published data', Journal of Allergy and Clinical Immunology, New Orleans, LA (2010) [E3]
Co-authors Peter Gibson
2010 McLernon PC, Wood LG, Murphy VE, Dekker GA, Clifton VL, 'Maternal circulating levels of omega (N)3 long chain polyunsaturated fatty acids, eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaunoic acid (DHA) during early pregnancy are associated with detal growth meaures in later pregnancy', Placenta, Kumamoto, Japan (2010) [E3]
Co-authors Lisa Wood
2010 Vanders RL, Gibson PG, Murphy VE, Wark PA, 'Reduced anti-viral responses: Why pregnant women have increased susceptibility to respiratory virus infection', American Journal of Respiratory and Critical Care Medicine, New Orleans, LO (2010) [E3]
Co-authors Peter Wark, Peter Gibson, Rebecca Vanders
2010 Vanders RL, Gibson PG, Murphy VE, Wark PA, 'Reduced anti-viral responses: Why pregnant women have increased susceptiblty to respiratory virus infection', Respirology, Brisbane, QLD (2010) [E3]
Co-authors Rebecca Vanders, Peter Wark, Peter Gibson
2010 Murphy VE, Namazy J, Powell GH, Gibson PG, Chambers C, Attia JR, Schatz M, 'A meta-analysis of adverse perinatal outcomes in asthmatic women: Effect of asthma on maternal and neonatal outcomes', Respirology, Brisbane, QLD (2010) [E3]
Co-authors Peter Gibson, John Attia
2010 Murphy VE, Namazy J, Powell GH, Schatz M, Chambers C, Attia JR, Gibson PG, 'A meta-analysis of adverse perinatal outcomes in asthmatic women: Effect of asthma on size at birth and timing of birth', Respirology, Brisbane, QLD (2010) [E3]
Co-authors John Attia, Peter Gibson
2009 Murphy VE, Clifton VL, Gibson PG, 'The effect of cigarette smoking on asthma control and exacerbations in pregnant women', Respirology, Darwin, NT (2009) [E3]
DOI 10.1111/j.1440-1843.2009.01503_1.x
Co-authors Peter Gibson
2009 Powell H, Murphy VE, Gibson PG, 'The relationship between feno and atopic status in pregnant women with asthma', Respirology, Darwin, NT (2009) [E3]
DOI 10.1111/j.1440-1843.2009.01503_1.x
Co-authors Peter Gibson
2009 McLaughlin KM, Murphy VE, McCaffery K, Powell H, Clifton VL, Giles W, et al., 'The relationship between patient perceived risk of inhaled corticosteroids in pregnancy and medication adherence', Respirology, Darwin, NT (2009) [E3]
Co-authors Peter Gibson, Michael Hensley, Karen Mclaughlin
2008 Murphy VE, Clifton VL, Gibson PG, 'Characterization of asthma control and airway inflammation during exacerbations in pregnancy', American Journal of Respiratory and Critical Care Medicine, Toronto, ONT (2008) [E3]
Co-authors Peter Gibson
2008 McLernon PC, Wood LG, Murphy VE, Dekker GA, Clifton VL, 'Maternal circulating antioxidant levels in pregnancies complicated by asthma', 51st Annual Scientific Meeting of the Endocrine Society of Australia and Society of Reproductive Biology: Meeting Proceedings and Abstract Book, Melbourne, VIC (2008) [E3]
Co-authors Lisa Wood
2008 Hodyl N, Wyper H, Scott NM, Osei-Kumah A, Murphy VE, Smith R, Clifton VL, 'Relationship between placental glucocorticoid receptor expression and fetal growth in pregnancies complicated by asthma', 51st Annual Scientific Meeting of the Endocrine Society of Australia and Society of Reproductive Biology: Meeting Proceedings and Abstract Book, Melbourne, VIC (2008) [E3]
Co-authors Roger Smith
2008 McLaughlin K, Murphy VE, McCaffery K, Powell H, Clifton V, Giles W, et al., 'The relationship between patient perceived risk of inhaled corticosteroids in pregnancy and medication adherence', Australian Asthma Conference 2008: Conference Program & Abstract Book, Sydney, NSW (2008) [E3]
Co-authors Peter Gibson
2007 Murphy VE, Clifton VL, Gibson PG, 'Fractional exhaled nitric oxide (FENO) in pregnant women with and without asthma', Respirology (TSANZ Abstracts-Posters), Auckland (2007) [E3]
Co-authors Peter Gibson
2006 Micallef MA, Garg ML, Wood LG, Murphy VE, Clifton VL, 'Dietry intake of long chain n-3 polyunsaturated fatty acids in adults with asthma', Asia Pacific Journal of Clinical Nutrition, Sydney, New South Wales (2006) [E3]
Co-authors Manohar Garg, Lisa Wood
2006 Scott NM, Wyper HJ, Osei-Kumah A, Smith R, Murphy VE, Clifton VL, 'Sex specific differences in placental cytokine expression and their relationship to fetal glucocorticoid exposure', Journal of the Society for Gynecologic Investigation. Scientific Program and Abstracts 53rd Annual Meeting, Toronto, Ontario (2006) [E3]
Co-authors Roger Smith
2005 Murphy VE, Clifton VL, Talbot PI, Gibson PG, 'Severe asthma exacerbations during pregnancy', Perinatal Society of Australia and New Zealand 9th Annual Congress, Adelaide, 13-16 March, 2005, Adelaide (2005) [E3]
Citations Scopus - 162Web of Science - 147
Co-authors Peter Gibson
2005 Murphy VE, Clifton VL, Gibson PG, 'Asthma exacerbations during pregnancy are associated with low birth weight', European Respiratory Journal, Switzerland (2005) [C3]
Co-authors Peter Gibson
2005 Wynne OL, Clifton VL, Murphy VE, Hodyl NA, Krivanek K, Smith D, et al., 'The Effects of Prenatal Endotoxin Exposure on Placental 11-HSD2 Activity and the Developing HPA Axis in the Fischer 344 Rat', Australian Neuroscience Society: Proceedings of the 25th Annual, Perth, Australia (2005) [E3]
Co-authors Philip Hansbro, Deborah Hodgson, Olivia Wynne
2005 Murphy VE, Talbot PI, Clifton VL, Gibson PG, 'Severe asthma exacerbations during pregnancy', American Journal of Respiratory and Critical Care, New York (2005) [C3]
Co-authors Peter Gibson
2005 Murphy VE, Clifton VL, Talbot PI, Gibson PG, 'Self-management education for pregnant women with asthma', American Journal of Respiratory and Critical Care Medicine, New York (2005) [C3]
Co-authors Peter Gibson
2005 Gibson PG, Giles WB, Zakar T, Smith R, Kessell CG, Clifton VL, Murphy VE, 'Inflammatory factors have sex-specified effects on fetal growth in humans', Ceska Gynekologie, Czech Republic (2005) [C3]
Co-authors Peter Gibson, Roger Smith
2005 Murphy VE, Talbot PI, Clifton VL, Gibson PG, 'Severe asthma exacerbations during pregnancy', Respirology, Philadelphia (2005) [C3]
DOI 10.1097/01.AOG.0000185281.21716.02
Co-authors Peter Gibson
2005 Murphy VE, Clifton VL, Talbot PI, Gibson PG, 'Self-management education for pregnant women with asthma. Thoracic Society of Australia and New Zealand Annual Scientific Meeting, Perth, 18-23 March, 2005', Respirology, - (2005) [C3]
Co-authors Peter Gibson
2005 Murphy VE, Talbot PI, Gibson PG, 'The prevalence and cycle to cycle variability of premenstrual asthma', Respirology, Hoboken (2005) [C1]
DOI 10.1111/j.1440-1843.2005.00663.x-i1
Co-authors Peter Gibson
2005 Fittock R, Murphy VE, Smith R, Zarzycki PK, Clifton VL, 'Metabolism of synthetic glucocorticoids used for the treatment of asthma by placental 11beta-hydoxysteroid dehydrogenase 2', Endocrine Society of Australia Annual Scientific Meeting, Adelaide, 22-25 Sept, 2002, Adelaide (2005) [E3]
Co-authors Roger Smith
2005 Clifton VL, Murphy VE, Gibson PG, Smith R, Giles WB, Scott N, 'Gender specific differences in response to changes in glucocorticoid concentration in the human fetus: Relationship to birthweight', PEDIATRIC RESEARCH, Toronto, CANADA (2005)
Co-authors Roger Smith, Peter Gibson
2004 Clifton VL, Murphy VE, Osei-Kumah A, Giles WB, Smith R, Gibson PG, 'Gender specific mechanisms of human fetal cortisol metabolism and immunity.', JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, Houston, TX (2004)
Co-authors Peter Gibson, Roger Smith
2004 Gibson PG, Murphy VE, Kessell CG, Talbot PI, Giles WB, Smith R, Clifton VL, 'Effect of fetal gender on maternal athsma during pregnancy', American Journal of Respiratory Care, Not Known (2004) [C3]
Co-authors Roger Smith, Peter Gibson
2004 Talbot PI, Murphy VE, Kessell CG, Giles WB, Smith R, Gibson PG, Clifton VL, 'Effect of fetal gender on maternal asthma during pregnancy', Respirology, Australia (2004) [C3]
Co-authors Roger Smith, Peter Gibson
2004 Clifton VL, Murphy VE, Giles WB, 'Gender specific mechanisms of human fetal cortisol metabolism and immunity', Reproductive Sciences, United States (2004) [C3]
2004 Johnson RF, Mitchell CM, Murphy VE, Wang Y, Akinsanya K, Smith R, Zakar T, 'Proteomic analyss of proteins in the human amnion during late gestation and labor', reproductive Sciences, United States (2004) [C3]
Co-authors Roger Smith
2004 Murphy VE, Kessell CG, Talbot PI, Gibson PG, Clifton VL, 'Asthma education, lung function and inflammation in pregnant women: relation to birth weight', 8th Annual Conference of the Perinatal Society of Australia and New Zealand, Sydney, 15-19 March, 2004, Sydney (2004) [E3]
Co-authors Peter Gibson
2004 Clifton VL, Murphy VE, Gibson PG, 'Gender specific growth mechanisms in the human fetus', 8th Annual Conference of the Perinatal Society of Australia and New Zealand, Sydney, 15-19 March, 2004, Sydney (2004) [E3]
Co-authors Peter Gibson
2004 Delahunty M, Fittock R, Murphy VE, Smith R, Zarzycki PK, Clifton VL, 'Metabolism of synthetic glucocortcoids used for the treatment of asthma by the human placenta', Conference of the Perinatal Society of Australia and New Zealand, Sydney, 15-19 March, 2004, Sydney (2004) [E3]
Co-authors Roger Smith
2004 Murphy VE, Gibson PG, Kessell CG, Clifton VL, 'Asthma self-management education for pregnant women delivered in an antenatal clinic setting', Perinatal Scoiety of Australian and New Zealand 9th annual Congress, Adelaide, 13-16 March, Adealide (2004) [E3]
Co-authors Peter Gibson
2003 Murphy VE, Gibson PG, Giles WB, Smith R, Clifton VL, 'A novel model for examining fetal growth restriction in human pregnancy', Reproductive Sciences, United States (2003) [C3]
Co-authors Peter Gibson, Roger Smith
2003 Murphy VE, Johnson RF, Wang Y, Akinsanya K, Gibson PG, Smith R, Clifton VL, 'A proteomic analysis of maternal plasma, umbilical cord plasma and placenta in asthmatic and non-asthmatic pregnancies', Australian Society for Medical Research, National Scientific Conference, Glenelg, 22-24 Nov, 2003, Not Known (2003) [E3]
Co-authors Peter Gibson, Roger Smith
2003 Murphy VE, Gibson PG, Giles WB, Smith R, Clifton VL, 'The effect of fetal gender on maternal inflammation and lung function in asthmatic pregnancies', Endocrine Society of Australia Annual Meeting, Melbourne 14-17 Sept, 2003, Melbourne (2003) [E3]
Co-authors Peter Gibson, Roger Smith
2003 Scott NM, Osei-Kumah A, Murphy VE, Clifton VL, 'Are female fetuses more sensitive to the effects of inflammation than male fetuses?', Endocrine Society of Australian Annual Scientific Meeting, Melbourne, 14-17 Sept, 2003, Melbourne (2003) [E3]
2003 Murphy VE, Gibson PG, Giles WB, Smith R, Zarzycki PK, 'Placental and maternal inflammatory pathways in pregnancies complicated by asthma', Placenta, United Kingdom (2003) [C3]
Co-authors Roger Smith, Peter Gibson
2003 Clifton VL, Fittock R, Murphy VE, Smith R, 'Metabolism of semi-synthetic glucocorticoids by the human placenta', Placenta, United Kingdom (2003) [C3]
Co-authors Roger Smith
2002 Murphy VE, Zakar T, Smith R, Giles WB, Kessell CG, Clifton VL, 'Maternal asthma affects fetal growth in a gender specific manner and is associated with reduced placental 11beta-HSD2 activity and altered sensitivity to cortisol', Reproductive Sciences, United States (2002) [C3]
Co-authors Roger Smith
2002 Murphy VE, Gibson PG, Giles WB, Zakar T, Smith R, Kessell CG, Clifton VL, 'Sex-specific changes in placental function and fetal growth and development in pregnancies complicated by ashtma', Endocrine Society of Australia Annual Scientific Meeting, Adelaide, 22-25 Sept, 2002, Adelaide (2002) [E3]
Co-authors Roger Smith, Peter Gibson
2001 Murphy VE, Zakar T, Gibson PG, Giles WB, Smith R, Clifton VL, 'Pleacental 11beta-HSD2 activity in asthmatic women', Reproductive sciences, United States (2001) [C3]
Co-authors Peter Gibson, Roger Smith
2001 Murphy VE, Zakar T, Smith R, Giles WB, Gibson PG, Clifton VL, 'A potential mechnism for growth retardation in pregnancies complicated by asthma', Endocrine Society of Australia Annual Scientific Meeting, Gold Coast, 9-12 Sept, 2001, Gold Coast (2001) [E3]
Co-authors Peter Gibson, Roger Smith
Show 107 more conferences

Other (1 outputs)

Year Citation Altmetrics Link
2019 Lane A, Van Aswegen M, Turner-Presker M, Whalen O, Mattes J, Gibson P, et al., 'Sensory correlates of autism risk in the first year of life: A multi-cohort study.', (2019) [O1]
Co-authors Shelly Lane, Linda E Campbell, Joerg Mattes, Alison Lane
Edit

Grants and Funding

Summary

Number of grants 47
Total funding $9,836,245

Click on a grant title below to expand the full details for that specific grant.


20211 grants / $1,562,250

Personalised biomarker-guided management of asthma during pregnancy$1,562,250

Funding body: Department of Health

Funding body Department of Health
Project Team Doctor Vanessa Murphy
Scheme MRFF Investigator
Role Lead
Funding Start 2021
Funding Finish 2025
GNo G2000056
Type Of Funding C1300 - Aust Competitive - Medical Research Future Fund
Category 1300
UON Y

20204 grants / $3,387,339

Centre of Research Excellence in Asthma Treatable Traits (CREATT)$2,500,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Vanessa McDonald, Conjoint Professor Peter Gibson, Professor Richard Beasley, Conjoint Professor Andrew Searles, Doctor Vanessa Murphy, Prof Philip Bardin, Professor Anne Holland, Professor Ian Pavord, Professor John Upham, Professor Michael Peek
Scheme Centres of Research Excellence - Centres of Clinical Research Excellence (CRE)
Role Investigator
Funding Start 2020
Funding Finish 2025
GNo G1901428
Type Of Funding C1100 - Aust Competitive - NHMRC
Category 1100
UON Y

Bushfire Impact on Vulnerable Groups: the respiratory burden and effective community solution$865,177

Funding body: Department of Health

Funding body Department of Health
Project Team Conjoint Professor Peter Gibson, Doctor Megan Jensen, Professor Vanessa McDonald, Associate Professor Jay Horvat, Doctor Vanessa Murphy, Associate Professor Liz Holliday, Conjoint Associate Professor Anne Vertigan
Scheme MRFF - EPCDR - Bushfire Impact
Role Investigator
Funding Start 2020
Funding Finish 2021
GNo G2000105
Type Of Funding C1300 - Aust Competitive - Medical Research Future Fund
Category 1300
UON Y

The development of gestational diabetes in pregnant women with asthma$12,162

Funding body: John Hunter Hospital Charitable Trust

Funding body John Hunter Hospital Charitable Trust
Project Team Doctor Megan Jensen, Doctor Vanessa Murphy, Doctor Daniel Barker, Dr Andy Woods
Scheme Research Grant
Role Investigator
Funding Start 2020
Funding Finish 2022
GNo G2001193
Type Of Funding C3112 - Aust Not for profit
Category 3112
UON Y

Investigating the health effects of bushfire smoke exposure, specifically on people with asthma, including pregnant women with asthma, and their children$10,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Conjoint Professor Peter Gibson, Doctor Vanessa Murphy, Professor Vanessa McDonald, Doctor Adam Collison, Conjoint Associate Professor Anne Vertigan, Doctor Megan Jensen, Doctor Dennis Thomas, Associate Professor Jay Horvat, Professor Maralyn Foureur, Professor Leigh Kinsman, Associate Professor Liz Holliday, Doctor Erin Harvey, Ms Alycia Jacob, Professor Joerg Mattes, Graeme Zosky, Wilfried Karmaus, Michele Goldman, Dr Craig Dalton
Scheme Research Grant
Role Investigator
Funding Start 2020
Funding Finish 2020
GNo G2000414
Type Of Funding C3120 - Aust Philanthropy
Category 3120
UON Y

20191 grants / $10,000

Blood biomarker predictors of exacerbations of asthma during pregnancy, and their relationship to adverse perinatal outcomes $10,000

Funding body: Society of Obstetric Medicine of Australia and New Zealand

Funding body Society of Obstetric Medicine of Australia and New Zealand
Project Team Doctor Vanessa Murphy, Doctor Katie Baines, Doctor Megan Jensen
Scheme Research Grant
Role Lead
Funding Start 2019
Funding Finish 2019
GNo G1901011
Type Of Funding C3111 - Aust For profit
Category 3111
UON Y

20182 grants / $66,934

Implementation of an asthma management strategy utilising measurement of airway inflammation in a hospital-based antenatal clinic setting$49,627

Funding body: Ramaciotti Foundations

Funding body Ramaciotti Foundations
Project Team Doctor Vanessa Murphy, Conjoint Professor Peter Gibson
Scheme Health Investment Grant
Role Lead
Funding Start 2018
Funding Finish 2018
GNo G1800731
Type Of Funding C3112 - Aust Not for profit
Category 3112
UON Y

Maternal and early life Vitamin D exposure and respiratory outcomes in high risk infants$17,307

Funding body: John Hunter Hospital Charitable Trust

Funding body John Hunter Hospital Charitable Trust
Project Team Doctor Megan Jensen, Doctor Vanessa Murphy, Emeritus Professor Michael Hensley
Scheme Research Grant
Role Investigator
Funding Start 2018
Funding Finish 2018
GNo G1800348
Type Of Funding C3112 - Aust Not for profit
Category 3112
UON Y

20172 grants / $29,866

Nutritional status and exacerbation risk in pregnant women with asthma$20,000

Funding body: John Hunter Hospital Charitable Trust

Funding body John Hunter Hospital Charitable Trust
Project Team Doctor Megan Jensen, Doctor Vanessa Murphy, Emeritus Professor Michael Hensley
Scheme Research Grant
Role Investigator
Funding Start 2017
Funding Finish 2017
GNo G1700387
Type Of Funding C3112 - Aust Not for profit
Category 3112
UON Y

Early and Mid-Career (EMCR) Equipment Grant$9,866

Funding body: NSW Ministry of Health

Funding body NSW Ministry of Health
Project Team Doctor Linda Campbell, Professor Alison Lane, Doctor Vanessa Murphy
Scheme Medical Research Support Program (MRSP)
Role Investigator
Funding Start 2017
Funding Finish 2017
GNo G1701281
Type Of Funding C2220 - Aust StateTerritoryLocal - Other
Category 2220
UON Y

20162 grants / $51,745

CELL-DYN Ruby Hematology Analyser (Abbott Haemotology)$30,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Vanessa McDonald, Conjoint Professor Peter Gibson, Professor Jodie Simpson, Conjoint Professor Peter Wark, Professor Lisa Wood, Doctor Vanessa Murphy
Scheme Equipment Grant
Role Investigator
Funding Start 2016
Funding Finish 2016
GNo G1601306
Type Of Funding C2120 - Aust Commonwealth - Other
Category 2120
UON Y

Airway resistance, body composition and wheeze in young children at high risk of asthma$21,745

Funding body: John Hunter Hospital Charitable Trust

Funding body John Hunter Hospital Charitable Trust
Project Team Doctor Megan Jensen, Doctor Vanessa Murphy, Emeritus Professor Michael Hensley
Scheme Research Grant
Role Investigator
Funding Start 2016
Funding Finish 2016
GNo G1600597
Type Of Funding C3112 - Aust Not for profit
Category 3112
UON Y

20157 grants / $1,666,490

The effect of asthma control during pregnancy on markers of airways inflammation and lung function in the offspring$1,135,272

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Joerg Mattes, Doctor Vanessa Murphy, Professor Peter Sly, Doctor Adam Collison, Professor Paul Robinson
Scheme Project Grant
Role Investigator
Funding Start 2015
Funding Finish 2019
GNo G1400050
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Optimising asthma management in pregnancy for optimal infant health$428,065

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Vanessa Murphy
Scheme Career Development Fellowships
Role Lead
Funding Start 2015
Funding Finish 2018
GNo G1400195
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

DVC(RI) Research Support for Career Development Fellow (CDF15)$59,287

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Vanessa Murphy
Scheme NHMRC CDF Support
Role Lead
Funding Start 2015
Funding Finish 2018
GNo G1500323
Type Of Funding Internal
Category INTE
UON Y

Viral infections in the BLT cohort in the first year of life$19,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Joerg Mattes, Doctor Vanessa Murphy, Doctor Adam Collison
Scheme Project Grant
Role Investigator
Funding Start 2015
Funding Finish 2015
GNo G1500671
Type Of Funding C3112 - Aust Not for profit
Category 3112
UON Y

Lung function in early life for children with high asthma risk$17,048

Funding body: Rebecca L Cooper Medical Research Foundation Ltd

Funding body Rebecca L Cooper Medical Research Foundation Ltd
Project Team Professor Joerg Mattes, Doctor Vanessa Murphy, Doctor Adam Collison
Scheme Research Grant
Role Investigator
Funding Start 2015
Funding Finish 2015
GNo G1500704
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Lillian Roxon Asthma Australia Travel Grant$6,818

Funding body: Asthma Australia

Funding body Asthma Australia
Project Team Doctor Vanessa Murphy
Scheme Lillian Roxon Asthma Australia Travel Grant
Role Lead
Funding Start 2015
Funding Finish 2015
GNo G1500772
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Perinatal Society of Australia and NewZealand, Melbourne Australia, 18-22 April 2015$1,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Doctor Vanessa Murphy
Scheme Travel Grant
Role Lead
Funding Start 2015
Funding Finish 2016
GNo G1500537
Type Of Funding Internal
Category INTE
UON Y

20142 grants / $1,724,020

The Breathing for Life Trial $1,722,020

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Vanessa Murphy, Conjoint Professor Peter Gibson, Emeritus Professor Michael Hensley, Professor Joerg Mattes, Professor Warwick Giles, Professor Michael Peek, Associate Professor Andrew Bisits, Associate Professor Leonie Callaway, Dr Helen Barrett
Scheme Project Grant
Role Lead
Funding Start 2014
Funding Finish 2018
GNo G1300106
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

European Respiratory Society International Congress, Munich Germany, 6 - 10 September 2014$2,000

Funding body: University of Newcastle - Faculty of Health and Medicine

Funding body University of Newcastle - Faculty of Health and Medicine
Project Team Doctor Vanessa Murphy
Scheme Travel Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1400839
Type Of Funding Internal
Category INTE
UON Y

20135 grants / $83,810

Impact of fractional exhaled nitric oxide-based management of pregnancies with asthma on perinatal and infant outcomes $23,810

Funding body: John Hunter Hospital Charitable Trust

Funding body John Hunter Hospital Charitable Trust
Project Team Doctor Vanessa Murphy, Emeritus Professor Michael Hensley
Scheme Research Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1300782
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

Inflammometry-based management of asthma in pregnancy for the prevention of preterm birth: the iMAP study$20,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Vanessa Murphy, Conjoint Professor Peter Gibson, Emeritus Professor Michael Hensley, Conjoint Professor Warwick Giles, Conjoint Associate Professor Andrew Bisits, Dr Kirsten McCaffery, Professor Paul Colditz, Professor Michael Peek
Scheme Near Miss Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1300477
Type Of Funding Internal
Category INTE
UON Y

Inflammometry-based management of asthma in pregnancy for the prevention of preterm birth: the iMAP study$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Vanessa Murphy
Scheme Near Miss
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1300695
Type Of Funding Donation - Aust Non Government
Category 3AFD
UON Y

Effect of better asthma management in pregnancy on antiviral responses, atopy and airways inflammation in early childhood$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Joerg Mattes, Conjoint Professor Peter Gibson, Doctor Vanessa Murphy
Scheme Near Miss Grant
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1300476
Type Of Funding Internal
Category INTE
UON Y

Effect of better asthma management in pregnancy on antiviral responses, atopy and airways inflammation in early childhood.$10,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Joerg Mattes, Conjoint Professor Peter Gibson, Doctor Vanessa Murphy
Scheme Near Miss
Role Investigator
Funding Start 2013
Funding Finish 2014
GNo G1300694
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20122 grants / $58,076

Body plethysmograph respiratory function system$33,076

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Gibson, Conjoint Professor Peter Wark, Professor Lisa Wood, Professor Jodie Simpson, Doctor Katie Baines, Doctor Vanessa Murphy, Doctor Jeffrey Pretto, Emeritus Professor Michael Hensley, Doctor Jenny Mackney
Scheme Equipment Grant
Role Investigator
Funding Start 2012
Funding Finish 2012
GNo G1100973
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

The Growing into Asthma Study: Wheezing prevalence and markers of airways inflammation in preschoolers born to mothers in asthma exacerbations in pregnancy$25,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Joerg Mattes, Conjoint Professor Peter Gibson, Emeritus Professor Michael Hensley, Conjoint Associate Professor Bruce Whitehead, Doctor Vanessa Murphy
Scheme Project Grant
Role Investigator
Funding Start 2012
Funding Finish 2013
GNo G1200662
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20111 grants / $10,000

Lung Function (Spirometry) testing and sputum induction equipment - establishing 3 new clinical workstations. Medgraphics CPFS/d USB spirometer with breezesuite software (x3). Laptop computer (x3). Ul$10,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Gibson, Professor Jodie Simpson, Professor Lisa Wood, Doctor Katie Baines, Conjoint Professor Peter Wark, Doctor Vanessa Murphy
Scheme Equipment Grant
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1100038
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20101 grants / $34,000

Real time PCR machine (Mastercycler ep realplex2 from Epprndorf) $34,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Jodie Simpson, Conjoint Professor Peter Gibson, Conjoint Professor Peter Wark, Professor Lisa Wood, Doctor Vanessa Murphy, Doctor Robert Scott, Doctor Katie Baines
Scheme Equipment Grant
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo G1000056
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20092 grants / $38,300

Growing into asthma: A birth cohort study to investigate the prenatal and development origins of asthma$24,800

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Vanessa Murphy, Professor Joerg Mattes, Conjoint Professor Peter Gibson
Scheme Project Grant
Role Lead
Funding Start 2009
Funding Finish 2009
GNo G0189802
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Growing into asthma: a birth cohort study to investigate the prenatal and development origins of asthma$13,500

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Vanessa Murphy, Professor Joerg Mattes, Conjoint Professor Peter Gibson
Scheme Project Grant
Role Lead
Funding Start 2009
Funding Finish 2009
GNo G0190487
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20082 grants / $39,000

Becton Dickinson high throughout sampler for the FACSCanto II cytometry system$35,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Professor Jodie Simpson, Professor Lisa Wood, Doctor Vanessa Murphy, Professor Phil Hansbro
Scheme Equipment Grant
Role Investigator
Funding Start 2008
Funding Finish 2008
GNo G0188547
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

PULSE Education Prize$4,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Vanessa Murphy
Scheme PULSE Education Prize
Role Lead
Funding Start 2008
Funding Finish 2008
GNo G0188538
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20076 grants / $672,250

Viral infection and exacerbations of asthma during pregnancy: characteristics, mechanisms and consequences$447,750

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Vanessa Murphy
Scheme Project Grant
Role Lead
Funding Start 2007
Funding Finish 2009
GNo G0186434
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Viral infection and exacerbations of asthma during pregnancy: characteristics, mechanisms and consequences$137,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Vanessa Murphy
Scheme Training (Postdoctoral) Fellowships - Australian Part-time Research Fellowship
Role Lead
Funding Start 2007
Funding Finish 2010
GNo G0186778
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Nitric Oxide Monitoring System (NIOX)$45,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Gibson, Conjoint Associate Professor Vicki Clifton, Conjoint Professor Warwick Giles, Emeritus Professor Michael Hensley, Doctor Vanessa Murphy, Conjoint Professor Peter Wark, Professor Vanessa McDonald, Professor Jodie Simpson, Conjoint Associate Professor Bruce Whitehead, Laureate Professor Paul Foster, Professor Phil Hansbro, Professor Lisa Wood
Scheme Equipment Grant
Role Investigator
Funding Start 2007
Funding Finish 2007
GNo G0188193
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Hewlett Packard 7890 series gas chromatograph with accessories$20,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Lisa Wood, Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Professor Jodie Simpson, Doctor Vanessa Murphy, Laureate Professor Paul Foster, Professor Phil Hansbro, Conjoint Associate Professor Vicki Clifton, Professor Clare Collins, Conjoint Professor Wayne Smith, Professor John Attia
Scheme Equipment Grant
Role Investigator
Funding Start 2007
Funding Finish 2007
GNo G0188191
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Class II biohazard containment hood and carbon dioxide cell culture incubator$20,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Professor Peter Wark, Conjoint Professor Peter Gibson, Professor Jodie Simpson, Doctor Vanessa Murphy, Professor Lisa Wood, Laureate Professor Paul Foster, Professor Phil Hansbro
Scheme Equipment Grant
Role Investigator
Funding Start 2007
Funding Finish 2007
GNo G0188192
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

American Thoracic Society Conference, San Francisco, 18/5/2007 - 23/5/2007$2,500

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Vanessa Murphy
Scheme Travel Grant
Role Lead
Funding Start 2007
Funding Finish 2007
GNo G0187767
Type Of Funding Internal
Category INTE
UON Y

20062 grants / $69,100

The relationship between eosinophilic inflammation, viral infection and severe asthma exacerbations during pregnancy$50,000

Funding body: Asthma Foundation of New South Wales

Funding body Asthma Foundation of New South Wales
Project Team Doctor Vanessa Murphy, Conjoint Associate Professor Vicki Clifton, Emeritus Professor Michael Hensley, Conjoint Professor Warwick Giles, Conjoint Professor Peter Gibson
Scheme Research Grant
Role Lead
Funding Start 2006
Funding Finish 2006
GNo G0186029
Type Of Funding Donation - Aust Non Government
Category 3AFD
UON Y

Viral infections and asthma exacerbations during pregnancy: characteristics, mechanisms and consequences$19,100

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Vanessa Murphy, Conjoint Associate Professor Vicki Clifton, Emeritus Professor Michael Hensley, Conjoint Professor Warwick Giles
Scheme Near Miss Grant
Role Lead
Funding Start 2006
Funding Finish 2006
GNo G0186061
Type Of Funding Internal
Category INTE
UON Y

20052 grants / $3,785

American Thoracic Society Conference, 20 to 25 May 2005$2,000

Funding body: Ian Potter Foundation

Funding body Ian Potter Foundation
Project Team Doctor Vanessa Murphy
Scheme Travel Grant
Role Lead
Funding Start 2005
Funding Finish 2005
GNo G0185081
Type Of Funding Donation - Aust Non Government
Category 3AFD
UON Y

American Thoracic Society Annual Scientific Conference, 20-25 May 2005$1,785

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Vanessa Murphy
Scheme Travel Grant
Role Lead
Funding Start 2005
Funding Finish 2005
GNo G0185399
Type Of Funding Internal
Category INTE
UON Y

20041 grants / $269,000

Respiratory Medicine$269,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Vanessa Murphy, Conjoint Professor Peter Gibson
Scheme Port Waratah Coal Service Post-Doctoral Fellowship
Role Lead
Funding Start 2004
Funding Finish 2006
GNo G0184012
Type Of Funding Donation - Aust Non Government
Category 3AFD
UON Y

20031 grants / $7,375

Identification of novel sex-specific factors derived from the human fetus.$7,375

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Vanessa Murphy
Scheme Travelling Award for Research Training
Role Lead
Funding Start 2003
Funding Finish 2003
GNo G0182186
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

20001 grants / $52,905

What causes preterm labour in asthmatic pregnancies? The role of placental 11beta-hydroxysteroid dehydrogenase type 2 and corticotropin releasing hormone$52,905

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Vanessa Murphy
Scheme Dora Lush Postgraduate Research Scholarship
Role Lead
Funding Start 2000
Funding Finish 2002
GNo G0181963
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y
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Research Supervision

Number of supervisions

Completed5
Current4

Current Supervision

Commenced Level of Study Research Title Program Supervisor Type
2017 PhD Smoking Cessation Treatment in Pregnant Women and its Impact on Their Offspring's Lung Function PhD (Paediatrics), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2017 PhD Inhaled Corticosteroid Non-Adherence during Pregnancy PhD (Medicine), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2017 PhD Maternal and Early Life Nutritional Status and Respiratory Health Outcomes of the Offspring PhD (Medicine), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2016 PhD Risk Factors for Impaired Lung Function and the Onset of Respiratory Disease in Early Life PhD (Paediatrics), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor

Past Supervision

Year Level of Study Research Title Program Supervisor Type
2020 PhD Breathe Easy, Think Clearly: the Relationships between Maternal Asthma, Maternal Mental Health and Infant Development PhD (Psychology - Science), Faculty of Science, The University of Newcastle Co-Supervisor
2020 PhD Usual Antenatal Asthma Management and the Clinical Translational Potential of a Fractional Exhaled Nitric Oxide (FeNO)-based Management Strategy PhD (Medicine), Faculty of Health and Medicine, The University of Newcastle Principal Supervisor
2020 PhD Breathing and Behaviour: Exploring Infant Temperament and Autism Risk in Infants Born to Mothers with Asthma PhD (Psychology - Science), Faculty of Science, The University of Newcastle Co-Supervisor
2014 Masters Asthma and Pregnancy: A Qualitative Descriptive Study of Midwives' Current Knowledge About Asthma in Pregnancy and Their Perceived Role in Antenatal Asthma Management in Australia M Philosophy (Midwifery), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2013 PhD Investigation of the Immune Mechanisms in Pregnancy and Asthma Leading to Increased Susceptibility and Disease Severity to Respiratory Virus Infections PhD (Medicine), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
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News

Major funding boost to explore the health impacts of recent bushfires

June 1, 2020

Researchers from the University of Newcastle, Hunter Medical Research Institute and Hunter New England Health have excelled in the latest round of National Health and Medical Research Council (NHMRC) funding, attracting more than $860,000 to analyse the physiological and mental health effects of haz

More than $10 million to support innovations in health service delivery

May 21, 2020

Six projects led by Hunter researchers have been successful in attracting a combined total of $10.6 million in the latest round of competitive National Health and Medical Research Council (NHMRC) funding.

Future research leaders receive funding boost

October 22, 2019

The inaugural Research Advantage NEWstar program will support 13 aspiring University of Newcastle mid-career researchers to further develop their research leadership skills.

New study: childhood asthma rates reduced with tailored intervention

May 16, 2018

Researchers have confirmed that when a woman’s asthma medication is optimally during pregnancy, the rate of asthma in her offspring is nearly halved.

Dr Vanessa Murphy

Position

Senior Lecturer
School of Medicine and Public Health
Faculty of Health and Medicine

Contact Details

Email vanessa.murphy@newcastle.edu.au
Phone (02) 40420141
Fax (02) 40420046

Office

Room HMRI West Wing Level 2
Building HMRI
Location Other

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