| 2025 |
Berthon BS, Williams LM, McLoughlin RF, Nichol KS, Negewo NA, Thompson CA, Williams EJ, Bartlett NW, Wark PAB, Wood LG, 'Pilot investigation of an oligosaccharide blend in adults with asthma - a double-blind, randomised, placebo-controlled, 4-arm crossover trial.', Respir Med (2025)
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| 2024 |
Valkenborghs SR, Wood LG, Callister R, Upham JW, Grainge CL, Anderson S, Williams LM, McLoughlin RF, Williams EJ, Scott HA, 'Effects of Moderate- Versus Vigorous-Intensity Exercise Training on Asthma Outcomes in Adults', JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 12 (2024) [C1]
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| 2023 |
Berthon BS, Williams LM, Williams EJ, Wood LG, 'Lactoferrin in the prevention of infections: some evidence of efficacy. Results of a systematic review with meta-analysis', Quaderni ACP, 30 (2023)
This systematic review included 25 studies including 5 pediatric studies (882 children) to evaluate the effect of lactoferrin (Lf) supplementation on inflammation, immu... [more]
This systematic review included 25 studies including 5 pediatric studies (882 children) to evaluate the effect of lactoferrin (Lf) supplementation on inflammation, immune function, and acute respiratory tract infections. The pediatric studies involved children in the first years of life in whom Lf supplementation was via milk formula at a highly variable dosage ranging from 35 to 833 mg Lf/day. The meta-analysis shows that Lf reduces systemic inflammation and the incidence of respiratory tract infections (VRI) in infants but not in adults. However, 1 of the 3 studies included in the pediatric meta-analysis was judged to be at high risk of bias due to missing data by the authors of another 2021 review that used the Cochrane risk of bias assessment (not adopted in this study) and there is high heterogeneity evidenced by an I2 of 81%. The result of this meta-analysis is not very robust, and further studies of good methodological quality are needed before recommending this type of supplementation to reduce the incidence of VRI in early life.
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| 2023 |
Stoodley IL, Williams LM, Wood LG, 'Effects of Plant-Based Protein Interventions, with and without an Exercise Component, on Body Composition, Strength and Physical Function in Older Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials', NUTRIENTS, 15 (2023) [C1]
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Open Research Newcastle |
| 2023 |
Williams LM, Berthon BS, Stoodley IL, Williams EJ, Wood LG, 'Medicinal Mushroom Extracts from Hericium coralloides and Trametes versicolor Exert Differential Immunomodulatory Effects on Immune Cells from Older Adults In Vitro', NUTRIENTS, 15 (2023) [C1]
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Open Research Newcastle |
| 2023 |
Antunes KH, Singanayagam A, Williams L, Faiez TS, Farias A, Jackson MM, Faizi FK, Aniscenko J, Kebadze T, Veerati PC, Wood L, Bartlett NW, de Souza APD, Johnston SL, 'Airway-delivered short-chain fatty acid acetate boosts antiviral immunity during rhinovirus infection', JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 151, 447-+ (2023) [C1]
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| 2022 |
Williams EJ, Berthon BS, Stoodley I, Williams LM, Wood LG, 'Nutrition in Asthma', SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE, 43, 646-661 (2022) [C1]
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Open Research Newcastle |
| 2022 |
Berthon BS, Williams LM, Williams EJ, Wood LG, 'Effect of Lactoferrin Supplementation on Inflammation, Immune Function, and Prevention of Respiratory Tract Infections in Humans: A Systematic Review and Meta-analysis', ADVANCES IN NUTRITION, 13, 1799-1819 (2022) [C1]
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Open Research Newcastle |
| 2021 |
Williams LM, Stoodley IL, Berthon BS, Wood LG, 'The Effects of Prebiotics, Synbiotics, and Short-Chain Fatty Acids on Respiratory Tract Infections and Immune Function: A Systematic Review and Meta-Analysis', ADVANCES IN NUTRITION, 13, 167-192 (2021) [C1]
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Open Research Newcastle |
| 2019 |
Williams LM, Scott HA, Wood LG, 'Soluble fibre as a treatment for inflammation in asthma', Journal of Nutrition and Intermediary Metabolism, 18 (2019) [C1]
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Open Research Newcastle |
| 2019 |
Stoodley I, Williams L, Thompson C, Scott H, Wood L, 'Evidence for lifestyle interventions in asthma', BREATHE, 15, E51-E61 (2019) [C1]
Asthma is a chronic inflammatory airways disease, estimated to affect 300 million people worldwide. Asthma management plans focus on optimisation of asthma pharmacother... [more]
Asthma is a chronic inflammatory airways disease, estimated to affect 300 million people worldwide. Asthma management plans focus on optimisation of asthma pharmacotherapy. Lifestyle interventions also hold great promise for asthma sufferers as they are accessible, low cost and have minimal side-effects, thus making adherence more likely. This review explores lifestyle interventions that have been tested in asthma, including improving nutrition, increasing physical activity and introduction of relaxation therapies such as yoga and massage therapy. Available evidence suggests a protective effect of increasing fruit, vegetable and wholegrain intake and increasing physical activity levels in asthma. Weight loss is recommended for obese asthmatic patients, as just 5¿10% weight loss has been found to improve quality of life and asthma control in most obese asthmatic patients. Other lifestyle interventions such as meditation, yoga and massage therapy show promise, with positive effects on asthma seen in some studies. However, the study protocols are highly variable and the results are inconsistent. Additional research is needed to further develop and refine recommendations regarding lifestyle modifications that can be implemented to improve asthma.
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Open Research Newcastle |
| 2018 |
Gao F, Griffin N, Faulkner S, Rowe CW, Williams L, Roselli S, Thorne RF, Ferdoushi A, Jobling P, Walker MM, Hondermarck H, 'The neurotrophic tyrosine kinase receptor TrkA and its ligand NGF are increased in squamous cell carcinomas of the lung', SCIENTIFIC REPORTS, 8 (2018) [C1]
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Open Research Newcastle |
