| 2023 |
Donovan C, Barnes JL, Kim RY, 'Back to the Eosinophil: Resolvin Spatiotemporal Regulation', AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 69, 608-609 (2023)
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Open Research Newcastle |
| 2023 |
Burns GL, Potter M, Mathe A, Bruce J, Minahan K, Barnes JL, Pryor J, Nieva C, Sherwin S, Cuskelly A, Fairlie T, Cameron R, Bollipo S, Irani MZ, Foster R, Gan LT, Shah A, Koloski N, Foster PS, Horvat JC, Walker MM, Powell N, Veysey M, Duncanson K, Holtmann G, Talley NJ, Keely S, 'TRAV26-2 T-Cell Receptor Expression Is Associated With Mucosal Lymphocyte Response to Wheat Proteins in Patients With Functional Dyspepsia', CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 14 (2023) [C1]
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Open Research Newcastle |
| 2022 |
Foster PS, Barnes JL, Tay HL, Gibson PG, 'Transcriptomic drug-response gene signatures are informative for the stratification of patients for clinical trials', JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 149, 55-57 (2022)
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| 2021 |
Barnes JL, Plank MW, Asquith K, Maltby S, Sabino LR, Kaiko GE, Lochrin A, Horvat JC, Mayall JR, Kim RY, Hansbro PM, Keely S, Belz GT, Tay HL, Foster PS, 'T-helper 22 cells develop as a distinct lineage from Th17 cells during bacterial infection and phenotypic stability is regulated by T-bet', MUCOSAL IMMUNOLOGY, 14, 1077-1087 (2021) [C1]
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Open Research Newcastle |
| 2020 |
Ali MK, Kim RY, Brown AC, Mayall JR, Karim R, Pinkerton JW, Liu G, Martin KL, Starkey MR, Pillar AL, Donovan C, Pathinayake PS, Carroll OR, Trinder D, Tay HL, Badi YE, Kermani NZ, Guo Y-K, Aryal R, Mumby S, Pavlidis S, Adcock IM, Weaver J, Xenaki D, Oliver BG, Holliday EG, Foster PS, Wark PA, Johnstone DM, Milward EA, Hansbro PM, Horvat JC, 'Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma', EUROPEAN RESPIRATORY JOURNAL, 55 (2020) [C1]
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Open Research Newcastle |
| 2019 |
Kaiko GE, Chen F, Lai C-W, Chiang I-L, Perrigoue J, Stojmirovic A, Li K, Muegge BD, Jain U, VanDussen KL, Goggins BJ, Keely S, Weaver J, Foster PS, Lawrence DA, Liu T-C, Stappenbeck TS, 'PAI-1 augments mucosal damage in colitis', SCIENCE TRANSLATIONAL MEDICINE, 11 (2019) [C1]
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Open Research Newcastle |
| 2018 |
Maltby S, Lochrin AJ, Bartlett B, Tay HL, Weaver J, Poulton IJ, Plank MW, Rosenberg HF, Sims NA, Foster PS, 'Osteoblasts Are Rapidly Ablated by Virus-Induced Systemic Inflammation following Lymphocytic Choriomeningitis Virus or Pneumonia Virus of Mice Infection in Mice', JOURNAL OF IMMUNOLOGY, 200, 632-642 (2018) [C1]
A link between inflammatory disease and bone loss is now recognized. However, limited data exist on the impact of virus infection on bone loss and regeneration. Bone lo... [more]
A link between inflammatory disease and bone loss is now recognized. However, limited data exist on the impact of virus infection on bone loss and regeneration. Bone loss results from an imbalance in remodeling, the physiological process whereby the skeleton undergoes continual cycles of formation and resorption. The specific molecular and cellular mechanisms linking virus-induced inflammation to bone loss remain unclear. In the current study, we provide evidence that infection of mice with either lymphocytic choriomeningitis virus (LCMV) or pneumonia virus of mice (PVM) resulted in rapid and substantial loss of osteoblasts from the bone surface. Osteoblast ablation was associated with elevated levels of circulating inflammatory cytokines, including TNF-a, IFN-g, IL-6, and CCL2. Both LCMV and PVM infections resulted in reduced osteoblast-specific gene expression in bone, loss of osteoblasts, and reduced serum markers of bone formation, including osteocalcin and procollagen type 1 N propeptide. Infection of Rag-1-deficient mice (which lack adaptive immune cells) or specific depletion of CD8+ T lymphocytes limited osteoblast loss associated with LCMV infection. By contrast, CD8+ T cell depletion had no apparent impact on osteoblast ablation in association with PVM infection. In summary, our data demonstrate dramatic loss of osteoblasts in response to virus infection and associated systemic inflammation. Further, the inflammatory mechanisms mediating viral infection-induced bone loss depend on the specific inflammatory condition.
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Open Research Newcastle |
| 2017 |
Plank MW, Kaiko GE, Maltby S, Weaver J, Tay H, Shen W, Wilson M, Durum S, Foster PS, 'Th22 Cells Form a Distinct Th Lineage from Th17 Cells In Vitro with Unique Transcriptional Properties and Tbet-Dependent Th1 Plasticity', Journal of Immunology, 198, 2182-2190 (2017) [C1]
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Open Research Newcastle |
| 2015 |
Plank MW, Maltby S, Tay HL, Stewart J, Eyers F, Hansbro PM, Foster PS, 'MicroRNA expression is altered in an ovalbumin-induced asthma model and targeting miR-155 with antagomirs reveals cellular specificity', PLoS ONE, 10 (2015) [C1]
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Open Research Newcastle |
| 2014 |
Maltby S, Hansbro NG, Tay HL, Stewart J, Plank M, Donges B, Rosenberg HF, Foster PS, 'Production and differentiation of myeloid cells driven by proinflammatory cytokines in response to acute pneumovirus infection in mice', Journal of Immunology, 193, 4072-4082 (2014) [C1]
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Open Research Newcastle |
| 2014 |
Holt JE, Pye V, Boon E, Stewart JL, Garcia-Higuera I, Moreno S, Rodriguez R, Jones KT, McLaughlin EA, 'The APC/C activator FZR1 is essential for meiotic prophase I in mice', DEVELOPMENT, 141, 1354-U327 (2014) [C1]
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Open Research Newcastle |
| 2011 |
Chang H-Y, Jennings PC, Stewart JL, Verrills NM, Jones KT, 'Essential role of protein phosphatase 2A in metaphase II arrest and activation of mouse eggs shown by okadaic acid, dominant negative protein phosphatase 2A, and FTY720', Journal of Biological Chemistry, 286, 14705-14712 (2011) [C1]
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Open Research Newcastle |
| 2011 |
Holt JE, Tran SM-T, Stewart JL, Minahan KL, Garcia-Higuera I, Moreno S, Jones KT, 'The APC/C activator FZR1 coordinates the timing of meiotic resumption during prophase I arrest in mammalian oocytes', Development, 138, 905-913 (2011) [C1]
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| 2010 |
Holt JE, Stewart JL, Jones KT, 'Spatial regulation of APC(Cdh1)-induced cyclin B1 degradation maintains G2 arrest in mouse oocytes', Development, 137, 1297-1304 (2010) [C1]
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Open Research Newcastle |
