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Career Summary

Biography

I am interested in the relationship between structure and function of cells in the vestibular (balance) system. Hair cells located in the vestibular component of the inner ear detect motion, acceleration, and gravity. I use immunofluorescent labeling techniques to show the presence of different proteins in vestibular hair cells and their afferent fibres.

Qualifications

  • PhD, Australian National University, 30/12/2001
  • Bachelor of Science, University of Newcastle, 31/12/1997
  • Bachelor of Science (Honours), University of Newcastle, 31/12/1997

Research

Research keywords

  • Central Vestibular System
  • Neurosciences
  • Peripheral Vestibular System
  • Physiology
  • Sensory Neurobiology

Research expertise

Sensory Neurobiology & the Physiology and anatomy of central vestibular neurons.

Fields of Research

CodeDescriptionPercentage
110905Peripheral Nervous System50
110903Central Nervous System25
110906Sensory Systems25

Administrative

Administrative expertise

Member of University Chemical Radiation Technical Committee

Teaching

Teaching keywords

  • Anatomy
  • Cellular Physiology
  • Head and Neck Anatomy
  • Neuroscience
  • Vestibular system

Teaching expertise

My teaching experience spans undergraduate, Honours, and PhD supervision.

I currently teach neurosciences and gross anatomy to first year students at UoN. I also supervise students during third year research projects.

I am also a Faculty member of ACAN (Australian Course in Advanced Neuroscience).

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Publications

For publications that are currently unpublished or in-press, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Chapter (3 outputs)

YearCitationAltmetricsLink
2014Wellings TP, Brichta AM, Lim R, 'Vestibular Adaptation and Compensation', Encyclopedia of Computational Neuroscience, Springer Verlag, Heidelberg Germany (2014)
2014Lim R, Wellings TP, Brichta AM, 'Central Vestibular Signal Processing', Encyclopedia of Computational Neuroscience, Springer Verlag, Heidelberg Germany (2014)
2012Lim R, Brichta AM, 'Vestibular system', The Mouse Nervous System, Academic Press, San Diego 661-678 (2012) [B1]

Co-authors: Alan Brichta

Journal article (20 outputs)

YearCitationAltmetricsLink
2014Lim R, Drury HR, Tadros MA, Callister RJ, Brichta AM, Camp AJ, 'Preliminary Characterization of Voltage-Activated Whole-Cell Currents in Developing Human Vestibular Hair Cells and Calyx Afferent Terminals', Journal of the Association for Research in Otolaryngology, (2014)
2014Poppi LA, Tabatabaee H, Callister RJ, Lim R, Brichta AM, 'Peripheral efferent vestibular system and fast cholinergic activity', J Vestib Res, 24 190-191 (2014)
2014Wellings TP, Graham BA, Camp AJ, Callister RJ, Brichta AM, Lim R, 'Calcium binding proteins subdivide medial vestibular nucleus neurons', J Vestib Res, 24 191-192 (2014)
2014Lim R, Drury HR, Camp AJ, Tadros MA, Callister RJ, Brichta AM, 'Anatomical and physiological characterisation of human vestibular hair cells.', J Vestib Res, 24 186-187 (2014)
2013Hübner PP, Lim R, Brichta AM, Migliaccio AA, ' Glycine Receptor Deficiency and Its Effect on the Horizontal Vestibulo-ocular Reflex: a Study on the SPD1J Mouse', Journal of the Association for Research in Otolaryngology, 14 249-259 (2013) [C1]
2013Tung VWK, Di Marco S, Lim R, Brichta AM, Camp AJ, ' An Isolated Semi-intact Preparation of the Mouse Vestibular Sensory Epithelium for Electrophysiology and High-resolution Two-photon Microscopy', Journal of Visualized Experiments, (2013) [C1]

DOI: 10.3791/50471

Co-authors: Alan Brichta

2012De Oliveira R, Gravina FS, Lim R, Brichta AM, Callister RJ, Van Helden DF, 'Heterogeneous responses to antioxidants in noradrenergic neurons of the Locus coeruleus indicate differing susceptibility to free radical content', Oxidative Medicine and Cellular Longevity, 2012 820285 (2012) [C1]
2011De Oliveira R, Gravina FS, Lim R, Brichta AM, Callister RJ, Van Helden DF, 'Developmental changes in pacemaker currents in mouse locus coeruleus neurons', Brain Research, 1425 27-36 (2011) [C1]
2011Lim R, McPherson AE, Donne SW, Callister RJ, Brichta AM, 'Potassium accumulation between type I hair cells and calyx terminals in mouse crista', Experimental Brain Research, 210 607-621 (2011) [C1]
2010Camp AJ, Lim R, Anderson WB, Schofield PR, Callister RJ, Brichta AM, 'Attenuated glycine receptor function reduces excitability of mouse medial vestibular nucleus neurons', Neuroscience, 170 348-360 (2010) [C1]
2010De Oliveira R, Graham BA, Howlett MC, Gravina FS, Oliveira MW, Imtiaz MS, et al., 'Ketamine anesthesia helps preserve neuronal viability', Journal of Neuroscience Methods, 189 230-232 (2010) [C1]
2010Lim R, Callister RJ, Brichta AM, 'An increase in glycinergic quantal amplitude and frequency during early vestibular compensation in mouse', Journal of Neurophysiology, 103 16-24 (2010) [C1]
2010Lim R, Camp AJ, Walsh MA, Callister RJ, Brichta AM, 'In vitro whole-cell conductances recorded from developing human cristae.', J Vestib Res, 285-286 (2010)
2010Lim R, Stitt IM, Camp AJ, Walsh MA, Callister RJ, Brichta AM, 'Inhibitory synaptic transmission in the lateral vestibular nucleus.', J. Vestib. Res, 286-287 (2010)
2008Jobling P, Lim R, 'Anatomical and physiological properties of pelvic ganglion neurons in female mice', Autonomic Neuroscience: Basic & Clinical, 140 30-39 (2008) [C1]
2004Lim R, Hoang P, Berger AJ, 'Blockade of glycine transporter-1 (GLYT-1) potentiates NMDA receptor-mediated synaptic transmission in hypoglossal motorneurons', Journal of Neurophysiology, 92 2530-2537 (2004) [C1]
2003Lim R, Oleskevich S, Few AP, Leao RN, Walmsley B, 'Glycinergic mIPSCs in mouse and rat brainstem auditory nuclei: modulation by ruthenium red and the role of calcium stores', The Journal of Physiology, 546 691-699 (2003) [C1]
2000Lim R, Alvarez FJ, Walmsley BJ, 'GABA mediates presynaptic inhibition at glycinergic synapses in a rat auditory brainstem nucleus', J Physiol., 525 Pt 2 447-459 (2000) [C1]
1999Lim R, Alvarez FJ, Walmsley B, 'Quantal size is correlated with receptor cluster area at glycinergic synapses in the rat brainstem.', J Physiol., 516 ( Pt 2) 505-512 (1999) [C1]
1998Bellingham MC, Lim R, Walmsley B, 'Developmental changes in EPSC quantal size and quantal content at a central glutamatergic synapse in rat.', J Physiol., 511 ( Pt 3) 861.-869. (1998) [C1]
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Conference (26 outputs)

YearCitationAltmetricsLink
2014Lim R, Drury HR, Camp AJ, Tadros MA, Callister RJ, Brichta AM, 'Anatomical and physiological characterisation of human vestibular hair cells', Journal of Vestibular Research: Equilibrium and Orientation: an international journal of experimental and clinical vestibular science, Buenos Aires, Argentina (2014)
2013Poppi LA, Tabatabaee H, Callister RJ, Lim R, Brichta AM, 'From the ear to the brain, and back again ¿ the Efferent Vestibular System', 4th UWS Sensory Neuroscience Symposium, Sydney (2013) [E3]
2013Poppi LA, Tabatabaee H, Callister RJ, Lim R, Brichta AM, 'Efferent Vestibular System ¿ the mysterious part of the periphery', Neuro-Otology Society of Australia, Melbourne (2013) [E3]
2013Huebner PP, Lim R, Brichta AM, Migliaccio AA, 'Glycine Receptor Deficiency and Its Effect on the Vestibulo-Ocular Reflex: A Study on the SPD1J Mouse', 36th Association for Research in Otolaryngology, Baltimore, MD (2013) [E3]

Co-authors: Alan Brichta

2013Wellings TP, Brichta AM, Lim R, 'Revealing the functional organisation of central vestibular nuclei', Neuro-Otology Society of Australia, Melbourne (2013) [E3]

Co-authors: Alan Brichta

2013Wellings TP, Callister RJ, Graham BA, Brichta AM, Lim R, 'Sensing balance: the role of central vestibular nuclei', University of Western Sydney Medical School, University of Western Sydney (2013)
2012Lim R, Callister RJ, Brichta AM, 'The other part of the ear - a 'balanced' view', Sydney 2012 Joint AuPS/PSNZ/ASB Meeting. Programme, Sydney, NSW (2012) [E3]
2012Lim R, Camp AJ, Tadros MA, Drury HR, Callister RJ, Brichta AM, 'Whole cell conductances of developing human hair cells', Abstracts. Australian Neuroscience Society 32nd Annual Meeting, Gold Coast, Queensland (2012) [E3]
2012Tadros MA, Lim R, Graham BA, Hughes DI, Brichta AM, Callister RJ, 'Excitability of human ventral horn neurons during early foetal development', Abstracts. Australian Neuroscience Society 32nd Annual Meeting, Gold Coast, Queensland (2012) [E3]
2012Stitt IM, Drury HR, Callister RJ, Brichta AM, Lim R, 'Anatomical and physiological characterization of mouse lateral vestibular nucleus neurons. 048', Association for Research in Otolaryngology, San Diego, California (2012)
2012Tadros MA, Jack R, Lim R, Graham BA, Brichta AM, Hughes DI, Callister RJ, 'Sensorimotor processing in the spinal cord of the developing human fetus', Society for Neuroscience, New Orleans, USA (2012)
2012Lim R, Kindig AE, Callister RJ, Brichta AM, 'A special relationship between vestibular hair cells and afferent nerve terminals', Neuro-Otology Society of Australia, Sydney (2012)
2012Lim R, Camp AJ, Tadros MA, Drury HR, Callister RJ, Brichta AM, 'Whole cell conductances of developing human hair cells. Mon 047', 32nd Proceedings of the Australian Neuroscience Society, Gold Coast, Queensland (2012)

Co-authors: Robert Callister

2012Lim R, Callister RJ, Holt JC, Migliaccio AA, Brichta AM, 'Efferent modulation of peripheral vestibular organs', Neuro-Otology Society of Australia, Sydney (2012)
2012Lim R, Stitt IM, Drury HR, Wellings TP, Callister RJ, Brichta AM, 'Electrophysiological characterization of mouse lateral vestibular nucleus neurons', Frontiers in Otolaryngology, Melbourne (2012)
2012Lim R, Camp AJ, Drury HR, Tadros MA, Callister RJ, Brichta AM, 'Characterisation of developing human hair cells', Association for Research in Otolaryngology, San Diego, California (2012)
2011Tadros MA, Lim R, Graham BA, Hughes DI, Brichta AM, Callister RJ, 'Excitability of human ventral horn neurons during early foetal development', Poster Abstracts. Australian Neuroscience Society Annual Meeting, Auckland, NZ (2011) [E3]
2010Lim R, Camp AJ, Walsh M, Callister RJ, Brichta AM, 'In-vitro whole-cell conductances recorded from developing human cristae', Journal of Vestibular Research, Reykavik, Iceland (2010) [E3]
2010Graham BA, Hughes DI, Lim R, Sah P, Brichta AM, Callister RJ, 'Characterization of calretinin expressing interneurons in the superficial dorsal horn of the mouse spinal cord', 13th World Congress on Pain: Abstracts, Montreal, QC (2010) [E3]
2010Lim R, Stitt I, Camp AJ, Callister RJ, Brichta AM, 'Inhibitory synaptic transmission in the lateral vestibular nucleus', Journal of Vestibular Research, Reykavik, Iceland (2010) [E3]
2009McPherson AE, Lim R, Callister RJ, Brichta AM, 'Voltage dependent currents in Type I and II hair cells and calyx terminals of primary afferents in an intact in vitro mouse vestibular crista preparation', Abstracts of the Thirty-Second Annual Midwinter Research Meeting Association for Research in Otolaryngology, Baltimore, MD (2009) [E3]
2009Lim R, Callister RJ, Brichta AM, 'Changes in glycinergic synaptic transmission and neuronal excitability in mouse medial vestibular nucleus neurons during early vestibular compensation', Abstracts of the Thirty-Second Annual Midwinter Research Meeting Association for Research in Otolaryngology, Baltimore, MD (2009) [E3]
2009Lim R, McPherson AE, Pow DV, Callister RJ, Brichta AM, 'Glutamate transport in the mouse inner ear is mediated by the excitatory amino acid transporter, EAAT5', Abstracts of the Thirty-Second Annual Midwinter Research Meeting Association for Research in Otolaryngology, Baltimore, MD (2009) [E3]
2009Lim R, Schofield PR, Callister RJ, 'Altered inhibitory synaptic transmission in spastic and spastic-rescue mice', ANS 2009 Abstracts: Posters, Canberra, ACT (2009) [E3]

Co-authors: Robert Callister

2009Brichta AM, Lamont E, Lim R, Callister RJ, 'Vestibular effects of endolymphatic ionic and volume changes in an isolated preparation of a mouse labyrinth', Abstracts of the Thirty-Second Annual Midwinter Research Meeting Association for Research in Otolaryngology, Baltimore, MD (2009) [E3]
2006Anderson WB, Graham BA, Jobling P, Lim R, Brichta AM, Callister RJ, 'Glycine receptor diversity in the dorsal horn of the mouse spinal cord', Society for Neuroscience, Atlanta, GA (2006) [E3]
Show 23 more
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Grants and Funding

Summary

Number of grants15
Total funding$2,011,515

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2014 (3 grants)

Physiological and Behavioural Characterisation of Central Vestibular Function$90,614
Funding Body: Garnett Passe and Rodney Williams Memorial Foundation

Project Team
Dr Thomas Wellings, Associate Professor Alan Brichta, Doctor Rebecca Lim
SchemeRole
Research ScholarshipInvestigator
Total AmountFunding StartFunding Finish
$90,61420142015
GNo:G1301066

2014 International Visitor from University of Utah, USA$9,750
Funding Body: University of Newcastle

Project Team
Doctor Rebecca Lim, Professor Richard Rabbitt
SchemeRole
International Research Visiting FellowshipChief Investigator
Total AmountFunding StartFunding Finish
$9,75020142014
GNo:G1400853

XXVIIIth Barany Society Meeting, Buenos Aires Argentina, 25-29 May 2014$2,000
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Doctor Rebecca Lim
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,00020142014
GNo:G1400598

2013 (2 grants)

Development of functional connections in the human peripheral vestibular system$418,281
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Rebecca Lim, Associate Professor Alan Brichta, Professor Robert Callister
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$418,28120132015
GNo:G1200254

Leica TP 1020 Automatic Tissue Processor for histology applications$35,000
Funding Body: NHMRC (National Health & Medical Research Council)

2012 (1 grants)

Association for Research in Otolaryngology 35th Annual Midwinter Meeting, San Diego, 25 - 29 February 2012$1,815
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Doctor Rebecca Lim
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,81520122012
GNo:G1200415

2011 (1 grants)

Efferent modulation of the vestibular periphery$339,208
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Alan Brichta, Professor Robert Callister, Doctor Rebecca Lim
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$339,20820112013
GNo:G1000315

2010 (3 grants)

Bridging the gap from mouse to man: Investigations of peripheral vestibular function$299,069
Funding Body: Garnett Passe and Rodney Williams Memorial Foundation

Project Team
Doctor Rebecca Lim, Dr Aaron Camp
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$299,06920102012
GNo:G0190594

ABI 7500 Real Time PCR System $34,000
Funding Body: NHMRC (National Health & Medical Research Council)

XXVI Barany Society meeting, Reykjavik, Iceland, 15 - 21st August 2010$1,500
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Doctor Rebecca Lim
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,50020102010
GNo:G1000137

2009 (3 grants)

Electron Microscopes for Nanometer-scale Imaging/Microanalysis in the Materials, Biological, Physical, Engineering and Chemical Sciences$650,000
Funding Body: ARC (Australian Research Council)

Electron Microscopes for Nanometer-scale Imaging/Microanalysis in the Materials, Biological, Physical, Engineering and Chemical Sciences$70,000
Funding Body: ARC (Australian Research Council)

Leica VT1200S - Fully automated vibrating blade microtome$16,209
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Robert Callister, Associate Professor Alan Brichta, Conjoint Professor Keith Jones, Associate Professor Jon Hirst, Doctor Brett Graham, Associate Professor Philip Bolton, Doctor Phil Jobling, Associate Professor Paul Tooney, Doctor Angela McPherson, Doctor Rebecca Lim, Doctor Ramatis De Oliveira, Mr Matthew Walsh
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$16,20920092009
GNo:G0189842

2008 (2 grants)

Recovery of the balance system following injury$24,069
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Alan Brichta, Professor Robert Callister, Associate Professor Philip Bolton, Doctor Phil Jobling, Doctor Rebecca Lim
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$24,06920082008
GNo:G0188471

Leica VT2100S Vibrating Microtome$20,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Alan Brichta, Professor Robert Callister, Professor Dirk Van Helden, Associate Professor Philip Bolton, Doctor Rebecca Lim, Doctor Brett Graham, Dr Marcus Howlett, Doctor Angela McPherson, Doctor Mohammad Imtiaz, Doctor Ramatis De Oliveira, Mr Wayne Anderson, Mr Matthew Walsh
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020082008
GNo:G0188540
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Research Supervision

Number of current supervisions2
Total current UoN PhD EFTSL0.95

For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20142018PhD (Anatomy)Co-SupervisorSynaptic Properties of the Peripheral Efferent Vestibular System
20122016PhD (Anatomy)Principal SupervisorPhysiological and Behavioural Characterisation of Central Vestibular Function
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Dr Rebecca Lim

Work Phone(02) 49217811
Fax(02) 49217812
Email
PositionSenior Lecturer
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine
The University of Newcastle, Australia
Focus AreaAnatomy
Office
MS309A,
Medical Sciences,
Callaghan
University Drive
Callaghan NSW 2308
Australia
URL:www.newcastle.edu.au/profile/rebecca-lim