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Staff Profile

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Career Summary

Qualifications

  • PhD, University of Newcastle
  • Bachelor of Science (Honours), University of Newcastle
  • Bachelor of Science, University of Newcastle

Research

Research keywords

  • Reproductive Biology

Research expertise

I obtained my PhD from the University of Newcastle (awarded 1999) working on a collaborative project with the Vertebrate Biocontrol CRC focused on characterising protein expression and function in male gametogenesis. This work helped to define to role of the male reproductive tract in post-testicular sperm maturation. I then undertook post-doctoral research in the Department of Cell Biology, Emory University, GA, USA (1999-2000). This work centred on the characterisation of a knockout mouse model bearing a targeted deletion of a key protein involved in gamete interactions. In 2001, I was recruited to the University of Newcastle as an Associate Lecturer in Biological Sciences and promoted to the position of Lecturer in 2004, Senior Lecturer in 2007, and Associate Professor in 2011. Since appointment I have established an active research program focusing on the use of human and animal models to characterise the processes of gamete maturation. In spermatozoa, I am working on a number of projects with the overriding goal of elucidating the molecular mechanisms that govern sperm activation and regulate gamete interactions. In folliculogenesis, I have focussed on cell signalling pathways that contribute to the initiation of primordial follicle activation and the effects of environmental ovotoxicants. These projects are of strategic importance in the design of post-testicular methods of fertility regulation, the development of assisted conception systems for the preservation of endangered species and elucidation of the causes of human male infertility.

My research niche complements existing programs in male germ cell development and ovarian biology within the Reproductive Science Group at the University of Newcastle. It also represents a strategically important subprogram of the University’s Priority Research Centre (PRC) for Reproductive Science. Furthermore, my research encompasses the National Research Priority goals of (i) safeguarding Australia (protecting Australia from invasive diseases and pests) and (ii) promoting and maintaining good health (a healthy start to life).

Languages

  • English

Fields of Research

CodeDescriptionPercentage
111499Paediatrics And Reproductive Medicine Not Elsewhere Classified50
060100Biochemistry And Cell Biology35
060899Zoology Not Elsewhere Classified15

Memberships

Editorial Board.

  • Editor - Molecular Human Reproduction

Learned Academy.

  • Member - Society for Reproductive Biology
  • Member - Society for the Study of Reproduction

Awards

Distinction.

2009Faculty of Science and IT Research Higher Degree Supervisor of the Year
The University of Newcastle (Australia)
Award for supervision excellence
2009The University of Newcastle Supervisor of the Year
The University of Newcastle (Australia)
Award for supervision excellence

Recognition.

2011Certificate of Recognition for excellent contribution to peer review
Human Reproduction (United Kingdom)
Certificate of Recognition for excellent contribution to Human Reproduction’s peer review process during 2011. Certificates are awarded to only the top 10% of the Journal’s reviewers as judged by the quality and timeliness of their reviews.
1998Finalist, Junior Scientist Competition
Australian Society for Reproductive Biology (Australia)

Research Award.

2012Award for Excellence in Reproductive Biology Research
Society for Reproductive Biology (Australia)
This award recognizes an excellent contributor working in the field of Reproductive Biology who is within 15 years post-receipt of their Doctorate. Criteria: The successful applicant will have demonstrated a substantial and sustained contribution to research in the field of Reproductive Biology. Evidence of such contribution to be considered includes: • Peer-Reviewed Publications • National and International Awards • National and International Invited Presentations • Student Completions • Grant Awards • Commercial and/or clinical translation • Institutional Responsibilities • Service to profession
2007New Investigator Grant
Hunter Medical Research Institute (Australia)
Grant awarded to junior scientists showing evidence of their potential to be group leaders
2006Lalor Foundation Award
American Society of Andrology (United States)
Awarded for presentation at the 31st Annual meeting of the American Society of Andrology, Chicago, IL, USA.
1998Student Travel Grant
American Society of Andrology (United States)
Awarded for presentation at the 23rd Annual meeting of the American Society of Andrology, Long Beach, CA, USA (1998)

Invitations

The Biology of Extracellular Molecular Chaperones
Novartis Foundation, United Kingdom (Conference Presentation - non published.)
2007

Collaboration

I have collaborative partnerships with a number of pre-eminent national and international scientists within the field of gamete biology. Similarly, I have established collaborations with IVF clinics to support the extension of my research program into the clinical domain. This nexus is critical for our ability to drive translational outcomes in understanding the aetiology of human male infertility.

Administrative

Administrative expertise

Service to the University

I am dedicated to building achievements in relation to University, Community and Professional Service. Since appointment to my current position I have made a significant commitment to University Service and related professional activities. Specifically, I focused on initiatives that enrich the student learning experience and promote a vibrant research culture, thus contributing to the status of the University's teaching and research profile. My committee membership aligns with my recognised strengths in teaching and research, and has included:

Faculty of Science and IT Student Recruitment Committee

School of Environmental and Life Sciences Honours Committee (Chair)

Discipline of Biological Sciences Postgraduate Committee

Analytical and Biomolecular Research Facility Advisory Committee

Reproductive Sciences OH&S Committee

Service to the profession

I review for a number of grant bodies such as NHMRC and Medical Research Council (UK). I also review for 12 specialist journals including Reproduction, Biology of Reproduction, Human Reproduction, Developmental Biology (~20 manuscripts/year) and serve as an Associate Editor for Molecular Human Reproduction.

Teaching

Teaching keywords

  • Biology

Teaching expertise

Undergraduate Teaching

Since my appointment in 2001, I have made a significant and sustained contribution to the teaching effort of the Discipline of Biological Sciences through the delivery of lectures and supervision of practical classes and tutorials across a broad range of courses (Levels 1000 – 4000). I strive for excellence in teaching and generate consistently high SEC and SET evaluations and qualitative feedback. My current teaching commitment includes:

BIOL1001 Cells, Molecules, and Organisms

BIOL1001 Gifted and Talented Program (Course coordinator)

BIOL2001 Molecular Laboratory Skills for Biological Sciences

BIOL2010 Biochemistry (Course coordinator)

BIOL2050 Molecular Genetics

BIOL3200 Cellular Biotechnology

BIOL3250 Biotechnology Placement

BIOL4110 - BIOL4220 BSc (Biology) Honours / BBiotech Honours (Program coordinator)

Research Training

Since 2001, I have supervised 6 PhD, 1 MPhil and 13 Honours students to successful completion of their research higher degrees. I am currently the principal supervisor of 3 PhD and 1 Honours student and the co-supervisor of an additional 3 PhD students. My commitment to research training is evidenced by the recent award of RHD Supervisor of the Year (2009), the University of Newcastle’s highest accolade for student supervision. The quality of my students is attested by the award of numerous platform and poster prizes at national and international meetings, including: best student poster at Lorne Protein (2003), Oozoa award for best student oral presentation at the Society for Reproduction (SRB) annual meeting (2008 & 2010), best student poster at the Australian Society for Biochemistry and Molecular Biology annual meeting (2010), best student poster at the International Symposium on Spermatology (Japan, 2010), and the SRB - New Investigator award (2011).

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Highlighted Publications

For publications that are currently unpublished or in-press, details are shown in italics.

YearCitationAltmetricsLink
2005Nixon B, Paul JW, Spiller CM, Attwell-Heap AG, Ashman LK, Aitken RJ, 'Evidence for the involvement of PECAM-1 in a receptor mediated signal-transduction pathway regulating capacitation-associated tyrosine phosphorylation in human spermatozoa', Journal of Cell Science, 118 4865-4877 (2005) [C1]
2006Nixon B, Macintyre DA, Mitchell LA, Gibbs GM, O'Bryan M, Aitken RJ, 'The identification of mouse sperm-surface-associated proteins and characterization of their ability to act as decapacitation factors', Biology of Reproduction, 74 275-287 (2006) [C1]
2005Ainsworth CJ, Nixon B, Aitken RJ, 'Development of a novel electrophoretic system for the isolation of human spermatozoa', Human Reproduction, 20 2261-2270 (2005) [C1]

Publications

For publications that are currently unpublished or in-press, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Chapter (3 outputs)

YearCitationAltmetricsLink
2012Redgrove KA, Aitken RJ, Nixon B, 'More than a simple lock and key mechanism: unraveling the intricacies of sperm-oocyte interactions', Binding Protein, InTech, Rijeka, Croatia 73-122 (2012) [B1]

Co-authors: John Aitken

2010Dun MD, Mitchell LA, Aitken RJ, Nixon B, 'Sperm-zona pellucida interaction: Molecular mechanisms and the potential for contraceptive intervention', Fertility Control, Springer, Berlin 139-178 (2010) [B1]

Co-authors: John Aitken, Matt Dun

2010Aitken RJ, Baker MA, De Iuliis GN, Nixon B, 'New insights into sperm physiology and pathology', Fertility Control, Springer, Berlin 99-115 (2010) [B1]

Journal article (64 outputs)

YearCitationAltmetricsLink
2014Bromfield EG, Aitken RJ, Gibb Z, Lambourne SR, Nixon B, 'Capacitation in the presence of methyl-beta-cyclodextrin results in enhanced zona pellucida-binding ability of stallion spermatozoa', REPRODUCTION, 147 153-166 (2014) [C1]
2014Nixon B, Ewen KA, Krivanek KM, Clulow J, Kidd G, Ecroyd H, Jones RC, 'Post-testicular sperm maturation and identification of an epididymal protein in the Japanese quail (Coturnix coturnix japonica)', REPRODUCTION, 147 265-277 (2014)
2014Nixon BJ, Katen AL, Stanger SJ, Schjenken JE, Nixon B, Roman SD, 'Mouse spermatocytes express CYP2E1 and respond to acrylamide exposure.', PLoS One, 9 e94904 (2014)
2013McIver SC, Roman SD, Nixon B, McLaughlin EA, Loveland KL, 'The rise of testicular germ cell tumours: The search for causes, risk factors and novel therapeutic targets [v1; ref status: Indexed, http://f1000r.es/md]', F1000 Research, 2 1-12 (2013) [C1]
2013McIver SC, Loveland KL, Roman SD, Nixon B, Kitazawa R, McLaughlin EA, 'The chemokine CXCL12 and its receptor CXCR4 are implicated in human seminoma metastasis', ANDROLOGY, 1 517-529 (2013) [C1]
2013Bromfield EG, Nixon B, 'The function of chaperone proteins in the assemblage of protein complexes involved in gamete adhesion and fusion processes', Reproduction, 145 R31-R42 (2013) [C1]
2013Aitken RJ, Nixon B, 'Sperm capacitation: a distant landscape glimpsed but unexplored', Molecular Human Reproduction, 19 785-793 (2013) [C1]
2013Redgrove KA, Anderson AL, McLaughlin EA, O'Bryan MK, Aitken RJ, Nixon B, 'Investigation of the mechanisms by which the molecular chaperone HSPA2 regulates the expression of sperm surface receptors involved in human spermoocyte recognition', MOLECULAR HUMAN REPRODUCTION, 19 120-135 (2013) [C1]
2013Lord T, Nixon B, Jones KT, Aitken RJ, 'Melatonin Prevents Postovulatory Oocyte Aging in the Mouse and Extends the Window for Optimal Fertilization In Vitro', Biology of Reproduction, 88 1-9 (2013) [C1]
2013McIver SM, Roman SD, Nixon B, Loveland KL, McLaughlin EA, 'The rise of testicular germ cell tumours: the search for causes, risk factors and novel therapeutic targets', F1000Research, 2:55 (doi: 10.12688/f1000research.2-55.v1) 55-66 (2013)
2012Dun MD, Aitken RJ, Nixon B, 'The role of molecular chaperones in spermatogenesis and the post-testicular maturation of mammalian spermatozoa', Human Reproduction Update, 18 420-435 (2012) [C1]
2012Nixon BJ, Stanger SJ, Nixon B, Roman SD, 'Chronic exposure to acrylamide induces DNA damage in male germ cells of mice', Toxicological Sciences, 129 135-145 (2012) [C1]

Co-authors: Shaun Roman

2012McIver SC, Stanger SJ, Santarelli DMF, Roman SD, Nixon B, McLaughlin EA, 'A unique combination of male germ cell mirnas coordinates gonocyte differentiation', PLoS One, 7 1-14 (2012) [C1]
2012Redgrove KA, Nixon B, Baker MA, Hetherington L, Baker G, Liu D-Y, Aitken RJ, 'The molecular chaperone HSPA2 plays a key role in regulating the expression of sperm surface receptors that mediate sperm-egg recognition', Plos One, 7 1-16 (2012) [C1]

Co-authors: John Aitken, Mark Baker

2012Sobinoff AP, Pye VJ, Nixon B, Roman SD, McLaughlin EA, 'Jumping the gun: Smoking constituent BaP causes premature primordial follicle activation and impairs oocyte fusibility through oxidative stress', Toxicology and Applied Pharmacology, 260 70-80 (2012) [C1]
2012Baker MA, Nixon B, Naumovski N, Aitken RJ, 'Proteomic insights into the maturation and capacitation of mammalian spermatozoa', Systems Biology in Reproductive Medicine, 58 211-217 (2012) [C1]
2012Reid AT, Lord T, Stanger SJ, Roman SD, McCluskey A, Robinson PJ, et al., 'Dynamin regulates specific membrane fusion events necessary for acrosomal exocytosis in mouse spermatozoa', Journal of Biological Chemistry, 287 37659-37672 (2012) [C1]
2012Sutherland JM, Keightley RA, Nixon B, Roman SD, Robker RL, Russell DL, McLaughlin EA, 'Suppressor of cytokine signaling 4 (SOCS4): Moderator of ovarian primordial follicle activation', Journal of Cellular Physiology, 227 1188-1198 (2012) [C1]
2012Dun MD, Anderson AL, Bromfield EG, Asquith KL, Emmett BJ, McLaughlin EA, et al., 'Investigation of the expression and functional significance of the novel mouse sperm protein, a disintegrin and metalloprotease with thrombospondin type 1 motifs number 10 (ADAMTS10)', International Journal of Andrology, 35 572-589 (2012) [C1]
2012Sobinoff AP, Nixon B, Roman SD, McLaughlin EA, 'Staying alive: PI3K pathway promotes primordial follicle activation and survival in response to 3MC-induced ovotoxicity', Toxicological Sciences, 128 258-271 (2012) [C1]
2012McIver SC, Roman SD, Nixon B, McLaughlin EA, 'miRNA and mammalian male germ cells', Human Reproduction Update, 18 44-59 (2012) [C1]
2011Nixon B, Ecroyd HW, Dacheux J-L, Jones RC, 'Monotremes provide a key to understanding the evolutionary significance of epididymal sperm maturation', Journal of Andrology, 32 665-671 (2011) [C1]
2011Sobinoff AP, Mahony M, Nixon B, Roman SD, McLaughlin EA, 'Understanding the villain: DMBA-induced preantral ovotoxicity involves selective follicular destruction and primordial follicle activation through PI3K/Akt and mTOR signaling', Toxicological Sciences, 123 563-575 (2011) [C1]
2011Ainsworth CJ, Nixon B, Aitken RJ, 'The electrophoretic separation of spermatozoa: An analysis of genotype, surface carbohydrate composition and potential for capacitation', International Journal of Andrology, 34 e422-e434 (2011) [C1]
2011Dun MD, Smith ND, Baker MA, Lin M, Aitken RJ, Nixon B, 'The chaperonin containing TCP1 complex (CCT/TRiC) is involved in mediating sperm-oocyte interaction', Journal of Biological Chemistry, 286 36875-36887 (2011) [C1]
2011Nixon B, Mitchell LA, Anderson AL, McLaughlin EA, O'Bryan MK, Aitken RJ, 'Proteomic and functional analysis of human sperm detergent resistant membranes', Journal of Cellular Physiology, 226 2651-2665 (2011) [C1]
2011Redgrove KA, Anderson AL, Dun MD, McLaughlin EA, O'Bryan MK, Aitken RJ, Nixon B, 'Involvement of multimeric protein complexes in mediating the capacitation-dependent binding of human spermatozoa to homologous zonae pellucidae', Developmental Biology, 356 460-474 (2011) [C1]
2010Nixon B, Bielanowicz AJ, Anderson AL, Walsh AK, Hall TE, McCloghry AK, Aitken RJ, 'Elucidation of the signaling pathways that underpin capacitation-associated surface phosphotyrosine expression in mouse spermatozoa', Journal of Cellular Physiology, 224 71-83 (2010) [C1]
2010Gibbs GM, Lo JCY, Nixon B, Jamsai D, O'Connor AE, Rijal S, et al., 'Glioma pathogenesis-related 1-Like 1 is testis enriched, dynamically modified, and redistributed during male germ cell maturation and has a potential role in sperm-oocyte binding', Endocrinology, 151 2331-2342 (2010) [C1]
2010Sobinoff AP, Pye VJ, Nixon B, Roman SD, McLaughlin EA, 'Adding insult to injury: Effects of xenobiotic-induced preantral ovotoxicity on ovarian development and oocyte fusibility', Toxicological Sciences, 118 653-666 (2010) [C1]
2010Reid AT, Redgrove KA, Aitken RJ, Nixon B, 'Cellular mechanisms regulating sperm-zona pellucida interaction', Asian Journal of Andrology, 13 88-96 (2010) [C1]
2009Ecroyd H, Nixon B, Dacheux J-L, Jones RC, 'Testicular descent, sperm maturation and capacitation: Lessons from our most distant relatives, the monotremes', Reproduction Fertility and Development, 21 992-1001 (2009) [C1]
2009Nixon B, Bielanowicz AJ, McLaughlin EA, Tanphaichitr N, Ensslin MA, Aitken RJ, 'Composition and significance of detergent resistant membranes in mouse spermatozoa', Journal of Cellular Physiology, 218 122-134 (2009) [C1]
2009Dacheux J-L, Dacheux F, Labas V, Ecroyd H, Nixon B, Jones RC, 'New proteins identified in epididymal fluid from the platypus (Ornithorhynchus anatinus)', Reproduction Fertility and Development, 21 1002-1007 (2009) [C1]
2009Nixon B, Aitken RJ, 'The biological significance of detergent-resistant membranes in spermatozoa', Journal of Reproductive Immunology, 83 8-13 (2009) [C1]
2009De Iuliis GN, Thomson LK, Mitchell LA, Read JM, Koppers AJ, Hedges A, et al., 'DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2'-deoxyguanosine, a marker of oxidative stress', Biology of Reproduction, 81 517-524 (2009) [C1]
2009Bennetts LE, De Iuliis GN, Nixon B, Kime M, Zelski K, McVicar CM, et al., 'Impact of estrogenic compounds on DNA integrity in human spermatozoa: Evidence for cross-linking and redox cycling activities', Journal of Urology, 181 914-915 (2009) [C3]
2009Aitken RJ, Nixon B, 'Proteomics of human spermatozoa', Immune Infertility: The Impact of Immune Reactions on Human Infertility, 3-12 (2009)
2008Nixon B, Jones RC, Holland MK, 'Molecular and functional characterization of the rabbit epididymal secretory protein 52, REP52', Biology of Reproduction, 78 910-920 (2008) [C1]
2008Grutzner F, Nixon B, Jones RC, 'Reproductive biology in egg-laying mammals', Sexual Development, 2 115-127 (2008) [C1]
2008Mitchell LA, Nixon B, Baker MA, Aitken RJ, 'Investigation of the role of SRC in capacitation-associated tyrosine phosphorylation of human spermatozoa', Molecular Human Reproduction, 14 235-243 (2008) [C1]
2008Bennetts LE, De Iuliis GN, Nixon B, Kime M, Nixon K, McVicar CM, et al., 'Impact of estrogenic compounds on DNA integrity in human spermatozoa: Evidence for cross-linking and redox cycling activities', Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 641 1-11 (2008) [C1]
2008Warren WC, Hillier LW, Graves JAM, Birney E, Ponting CP, Grutzner F, et al., 'Genome analysis of the platypus reveals unique signatures of evolution', Nature, 453 175-U1 (2008) [C1]
2008Priestley MN, Dunstan RH, O'Connor WA, Van Zwieten L, Nixon B, Macfarlane GR, 'Effects of 4-nonylphenol and 17 alpha-ethynylestradiol exposure in the Sydney rock oyster, Saccostrea glomerata: Vitellogenin induction and gonadal development', Aquatic Toxicology, 88 39-47 (2008) [C1]
2008Walsh AK, Whelan D, Bielanowicz AJ, Skinner BL, Aitken RJ, O'Bryan MK, Nixon B, 'Identification of the molecular chaperone, heat shock protein 1 (chaperonin 10), in the reproductive tract and in capacitating spermatozoa in the male mouse', Biology of Reproduction, 78 983-993 (2008) [C1]
2008Warren WC, Hillier LW, Graves JAM, Birney E, Ponting CP, Grutzner F, et al., 'Genome analysis of the platypus reveals unique signatures of evolution (vol 453, pg 175, 2008)', NATURE, 455 256-256 (2008) [C3]
2007Mitchell LA, Nixon B, Aitken RJ, 'Analysis of chaperone proteins associated with human spermatozoa during capacitation', Molecular Human Reproduction, 13 605-613 (2007) [C1]
2007Aitken RJ, Nixon B, Lin M, Koppers AJ, Lee YH, Baker MA, 'Proteomic changes in mammalian spermatozoa during epididymal maturation', Asian Journal of Andrology, 9 554-564 (2007) [C1]
2007Ainsworth CJ, Nixon B, Jansen RPS, Aitken RJ, 'First recorded pregnancy and normal birth after ICSI using electrophoretically isolated spermatozoa', Human Reproduction, 22 197-200 (2007) [C1]
2007Jones RC, Dacheux JL, Nixon B, Ecroyd HW, 'Role of the epididymis in sperm competition', Asian Journal of Andrology, 9 493-499 (2007) [C1]
2007Nixon B, Aitken RJ, McLaughlin EA, 'New insights into the molecular mechanisms of sperm-egg interaction', Cellular and Molecular Life Sciences, 64 1805-1823 (2007) [C1]
2006Nixon B, Macintyre DA, Mitchell LA, Gibbs GM, O'Bryan M, Aitken RJ, 'The identification of mouse sperm-surface-associated proteins and characterization of their ability to act as decapacitation factors', Biology of Reproduction, 74 275-287 (2006) [C1]
2005Nixon B, Asquith KL, Aitken RJ, 'The role of molecular chaperones in mouse sperm-egg interactions', Molecular and Cellular Endocrinology, 240 1-10 (2005) [C1]
2005Ainsworth CJ, Nixon B, Aitken RJ, 'Development of a novel electrophoretic system for the isolation of human spermatozoa', Human Reproduction, 20 2261-2270 (2005) [C1]
2005Nixon B, Paul JW, Spiller CM, Attwell-Heap AG, Ashman LK, Aitken RJ, 'Evidence for the involvement of PECAM-1 in a receptor mediated signal-transduction pathway regulating capacitation-associated tyrosine phosphorylation in human spermatozoa', Journal of Cell Science, 118 4865-4877 (2005) [C1]
2005Asquith KL, Bielanowicz AJ, McLaughlin EA, Nixon B, Aitken RJ, 'Localization and significance of molecular chaperones, heat shock protein 1, and tumor rejection antigen gp96 in the male reproductive tract and during capacitation and acrosome reaction', Biology of Reproduction, 72 328-337 (2005) [C1]
2004Asquith KL, Baleato R, McLaughlin EA, Nixon B, Aitken RJ, 'Tyrosine phosphorylation activates surface chaperones facilitating sperm-zona recognition', Journal of Cell Science, 117 3645-3657 (2004) [C1]
2004Curry BJ, Su H, Law EG, McLaughlin EA, Nixon B, Aitken RJ, 'Identification of RARhoGAP, a novel putative RhoGAP gene expressed in male germ cells', Genomics, 84 406-418 (2004) [C1]
2002Nixon B, Jones RC, Clarke H, Holland M, 'Rabbit epididymal secretory proteins. II. Immunolocalization and sperm association of REP38', Biology of Reproduction, 67 140-146 (2002) [C1]
2002Nixon B, Jones RC, Hansen LA, Holland M, 'Rabbit epididymal secretory proteins. I. Characterization and hormonal regulation', Biology of Reproduction, 67 133-139 (2002) [C1]
2002Nixon B, Hardy C, Jones RC, Anfrews J, Holland M, 'Rabbit epididymal secretory proteins. III. Molecular cloning and characterization of the complementary DNA for REP38', Biology of Reproduction, 67 147-153 (2002) [C1]
2001Nixon B, Lu QX, Wassler MJ, Foote CI, Ensslin MA, Shur BD, 'Galactosyltransferase function during mammalian fertilization', CELLS TISSUES ORGANS, 168 46-57 (2001) [C1]
1998Holland MK, Nixon B, 'The specificity of epididymal secretory proteins', Journal of Reproduction and Fertility, 197-210 (1998)
1997Hardy C, Clarke H, Nixon B, Hinds L, Holland M, 'Examination of the immunocontraceptive potential of recombinant fertilin subunits in rabbits', Biology of Reproduction, 57 879-886 (1997) [C1]
Show 61 more

Review (1 outputs)

YearCitationAltmetricsLink
2007Nixon B, Aitken RJ, McLaughlin EA, 'New insights into the molecular mechanisms of sperm-egg interaction', CELLULAR AND MOLECULAR LIFE SCIENCES (2007) [D1]

Conference (58 outputs)

YearCitationAltmetricsLink
2012Nixon B, Redgrove KA, Baker MA, Aitken RJ, 'The role of molecular chaperones in regulating human sperm-egg recognition', Abstracts. The Annual Scientific Meeting of the Endocrine Society of Australia and the Society for Reproductive Biology 2012, Gold Coast, QLD (2012) [E3]

Co-authors: John Aitken, Mark Baker

2012Nixon BJ, Katen AL, Stanger SJ, Nixon B, Roman SD, 'Identifying biomarkers of chronic acrylamide exposure in the male germ line', Abstracts. The Annual Scientific Meeting of the Endocrine Society of Australia and the Society for Reproductive Biology 2012, Gold Coast, QLD (2012) [E3]

Co-authors: Shaun Roman

2012Aitken RJ, Nixon B, Redgrove KA, Dun M, Baker MA, 'The molecular origins of defective sperm function', HUMAN REPRODUCTION, Istanbul, TURKEY (2012) [E3]
2012Sobinoff AP, Beckett EL, Nixon B, Roman SD, Hansbro PM, McLaughlin EA, 'The impact of maternal cigarette smoke exposure on the male germline', Abstracts. The Annual Scientific Meeting of the Endocrine Society of Australia and the Society for Reproductive Biology 2012, Gold Coast, QLD (2012) [E3]
2012Nixon B, 'Sperm maturation: Lessons from our distant relatives, the monotremes', Abstracts. The Annual Scientific Meeting of the Endocrine Society of Australia and the Society for Reproductive Biology 2012, Gold Coast, QLD (2012) [E3]
2011Dun MD, Aitken JR, Nixon B, 'The CCT/TRiC Complex Is Involved in Mediating Sperm-Oocyte Interaction', BIOLOGY OF REPRODUCTION, Portland, OR (2011) [E3]
2010Redgrove KA, Nixon B, McLaughlin EA, O'Bryan MK, Aitken RJ, 'Identification and Characterisation of Surface Protein Complexes in Human Spermatozoa', Reproduction, Fertility and Development, Sydney (2010) [E3]
2010Pye VJ, Sobinoff AP, Nixon B, Roman SD, McLaughlin EA, 'Xenobiotics; influence on long term oocyte viability', OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Vic (2010) [E3]
2010Reid AT, Roman SD, Aitken RJ, Nixon B, 'Investigation of the role of dynamin in sperm surface remodelling', OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Vic (2010) [E3]
2010Nixon BJ, Nixon B, Roman SD, 'The Consequences of Acrylamide Exposure on the Male Germline', Reproduction, Fertility and Development, Sydney (2010) [E3]

Co-authors: Shaun Roman

2010Redgrove KA, McLaughlin EA, O'Bryan MK, Aitken RJ, Nixon B, 'Identification and characterisation of surface protein complexes in human spermatozoa', OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Vic (2010) [E3]
2010Sobinoff AP, Pye VJ, Nixon B, Roman SD, McLaughlin EA, 'Short Term Xenobiotic Exposure Compromises Long Term Oocyte Viability', Reproduction, Fertility and Development, Sydney (2010) [E3]
2010Reid AT, Roman SD, Aitken RJ, Nixon B, 'Characterisation of the GTPASE dynamin throughout murine sperm maturation', Reproduction, Fertility and Development, Sydney, NSW (2010) [E3]
2010Nixon BJ, Nixon B, Roman SD, 'The effect of acrylamide exposure on early male germ cells', OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Vic (2010) [E3]

Co-authors: Shaun Roman

2010Anderson AL, Mitchell LA, McLaughlin EA, O'Bryan MK, Aitken RJ, Nixon B, 'Proteomic and Functional Analysis of Human Sperm Detergent Resistant Membranes', Reproduction, Fertility and Development, Sydney (2010) [E3]
2010McIver SC, Roman SD, Nixon B, McLaughlin EA, 'Microrna and Early Male Germ Cells', Reproduction, Fertility and Development, Sydney (2010) [E3]
2010McIver SC, Roman SD, Nixon B, McLaughlin EA, 'MicroRNA signalling in early male germ cells', OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Vic (2010) [E3]
2010Sobinoff AP, Pye VJ, Nixon B, Roman SD, McLaughlin EA, 'Consistent mechanism of primordial follicle activation in neonatal mouse ovotoxicity', OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Vic (2010) [E3]
2010Dun MD, Aitken RJ, Nixon B, 'The Chaperonin Containing TCP-1 (CCT/TRIC) Multisubunit Complex is Involved in Mediating Sperm-Oocyte Interactions', Reproduction, Fertility and Development, Sydney (2010) [E3]

Co-authors: John Aitken, Matt Dun

2008Ellis RJ, Henderson B, Lund PA, Coates ARM, Feder ME, Csermely P, et al., 'Discussion', Novartis Foundation Symposium (2008) [E2]
2008Feder ME, Calderwood SK, De Macario EC, Asea A, Multhoff G, Cheetham M, et al., 'Discussion', Novartis Foundation Symposium (2008) [E2]
2008Conway De Macario E, Ellis RJ, Csermely P, Lund PA, Cheetham M, Hightower LE, et al., 'Discussion', Novartis Foundation Symposium (2008) [E2]
2008Henderson B, Lund PA, Feder ME, Gupta RS, Hightower LE, Macario AJL, et al., 'Discussion', Novartis Foundation Symposium (2008) [E2]
2008Feder ME, Ellis RJ, Calderwood SK, De Macario EC, Gupta RS, Lund PA, et al., 'Discussion', Novartis Foundation Symposium (2008) [E2]
2008Asea A, Csermely P, De Macario EC, Hightower LE, Nixon B, Calderwood SK, et al., 'Discussion', Novartis Foundation Symposium (2008) [E2]
2008Nixon B, Bielanowicz AJ, McLaughlin EA, Tanphaichitr N, Ensslin M, Aitken RJ, 'The composition and significance of lipid rafts in mouse spermatozoa', Proceedings of 41st Annual Meeting of the Society for the Study of Reproduction., Kailua-Kona, Hawaii (2008) [E3]
2008Aitken R, Do Iuliis G, Nixon B, Roman S, 'Causes and clinical significance of DNA damage in the male germ line', BIOLOGY OF REPRODUCTION, Kona, HI (2008) [E3]
2008Panayi GS, Gupta RS, Csermely P, Asea A, Multhoff G, Coates ARM, et al., 'Discussion', Novartis Foundation Symposium (2008) [E3]
2008Mitchell L, Nixon B, Baker M, Aitken R, 'Investigation of the role of SRC in capacitation associated tyrosine phosphorylation of human spermatozoa', BIOLOGY OF REPRODUCTION, Kona, HI (2008) [E3]
2008Ellis RJ, Pockley AG, Henderson B, Hightower LE, Panayi GS, Quintana FJ, et al., 'General discussion', Novartis Foundation Symposium (2008) [E3]
2008Nixon B, Bielanowicz A, McLaughlin E, Tanphaichitr N, Ensslin M, Aitken R, 'The composition and significance of lipid rafts in mouse spermatozoa', BIOLOGY OF REPRODUCTION, Kona, HI (2008) [E3]
2008Mitchell LA, Nixon B, Aitken RJ, 'Investigation of the role of lipid rafts in human sperm-zona pellucida binding', Biology of Reproduction, Kailua-Kona, Hawaii (2008) [E3]

Co-authors: John Aitken

2008Lund PA, Corrigall VM, Habich C, Panayi GS, Nixon B, Hightower LE, et al., 'Discussion', Novartis Foundation Symposium (2008) [E3]
2008Aitken RJ, De Iuliis GN, Nixon B, Roman SD, 'Causes and clinical significance of DNA damage in the male germ line', Proceedings of 41st Annual Meeting of the Society for the Study of Reproduction. "Reproductive Biology: Basic Discoveries that Affect Our Lives", Kailua-Kona, Hawaii (2008) [E3]
2008Panayi GS, Asea A, Macario AJL, Triantafilou K, Nixon B, Csermely P, et al., 'Discussion', Novartis Foundation Symposium (2008) [E3]
2007Schjenken JE, Stanger SJ, Smith V, Douglas A, De Iuliis GN, Depaz I, et al., 'Expression and activity of phase 1 detoxifying enzymes in the male sperm line of the mouse', 7th Hunter Cellular Biology Meeting. Program, Hunter Valley, NSW (2007) [E3]
2007Jones RC, Dacheaux J-L, Nixon B, Ecroyd HW, 'The role of epididymis in sperm competition', Australian Mammal Society 53rd Scientific Meeting. Programme and Abstracts, Armidale, NSW (2007) [E3]
2006Nixon B, Walsh AK, Bielanowicz AJ, Aitken RJ, 'The role of molecular chaperones in sperm-oocyte interaction', Book of Abstracts, Chicago, Illinois (2006) [E3]

Co-authors: John Aitken

2006Mitchell LA, Nixon B, Macintyre DA, Gibbs GM, O'Bryan M, Aitken RJ, 'The Role of Decapacitation Factors in the Regulation of Mouse Sperm Capacitation', Book of Abstracts, Lorne, Victoria, Australia (2006) [E3]

Co-authors: John Aitken

2006Nixon B, Paul JW, Spiller CM, Attwell-Heap AG, Aitken RJ, 'Evidence for the Involvement of Pecam-1 in a Reception Mediated Signal-Transduction Pathway regulating Capacitation-Associated Tyrosine Phosphorylation in Human Spermatozoa', Book of Abstracts, Lorne, Victoria, Australia (2006) [E3]

Co-authors: John Aitken

2006Walsh AK, Bielanowicz AJ, Mitchell LA, Spiller CM, Nixon B, Aitken RJ, 'Identification of a Metalloprotease, Adamts10, in Complex with Sperm Surface Molecular Chaperones', Book of Abstracts, Lorne, Victoria, Australia (2006) [E3]

Co-authors: John Aitken

2006Aitken RJ, Baker MA, Lee YH, Lin M, Nixon B, 'Proteomic Changes in Mouse Spermatozoa During Epididymal Transit', Abstracts, Chatel-Guyon, Auvergne, France (2006) [E3]
2006Nixon B, Walsh A, Harman A, Aitken RJ, 'The role of molecular chaperones in sperm-oocyte interaction', JOURNAL OF ANDROLOGY, Chicago, IL (2006)
2005Aitken RJ, Bennets L, Wingate J, Koppers A, Gallagher S, Roman S, et al., 'Estrogenic steroids and quinines as mediators of DNA damage in the male germ line', Couran Cove (2005) [E3]
2005Dacheux J-L, Belghazi M, Dacheux F, Nixon B, Jones RC, 'The epididymis secretes proteins involved in sperm competition: Evidence from the echidna', Perth, Australia (2005) [E3]
2005Ainsworth C, Nixon B, Aitken RJ, 'Profiling of sperm populations fractionated using novel microflow electrophoretic device', Adelaide, Australia (2005) [E3]
2004Walsh AK, Asquith KL, Thomas CM, Mitchell LA, Nixon B, Aitken RJ, 'Identification of Potential Zona Pellucida-binding Sperm Proteins using Heat Shock Protein 60', Reproduction, Fertility and Development, Sydney (2004) [E3]

Co-authors: John Aitken

2004Nixon B, Bielanowicz AJ, Asquith KL, Aitken RJ, 'The Molecular Basis of Epididymal Sperm Maturation', Reproduction, Fertility and Development, Sydney (2004) [E3]

Co-authors: John Aitken

2004Asquith KL, Nixon B, McLaughlin EA, Aitken RJ, 'Tyrosine phosphorylation of mouse sperm proteins in a prerequisite for Zona Pellucida binding: potential involvement of molecular chaperones', Biology of Reproduction 2004 Special Issue, Vancouver, Canada (2004) [E3]
2003Jones RC, Clulow J, Kidd GJ, Chaturapanich G, Nixon B, Dacheux J, 'The Avian Epididymis: A Simple Conduit or a Sophisticated Adaptation?', The Third International Conference on the Epididymis, Charlottesville, Virginia (2003) [E2]

Co-authors: John Clulow

2003Nixon B, Attwell-Heap AG, Paul JW, Aitken RJ, 'Wheat Germ Agglutinin Induced Tyrosine Phosphorylation of Human Spermatozoa', Reproduction, Fertility and Development, Melbourne (2003) [E3]

Co-authors: John Aitken

2003Nixon B, Paul JW, Aitken RJ, 'Wheat germ agglutinin induced tyrosine phosphorylation of human spermatozoa', 28th Annual Lorne Conference on Protein Structure & Function, Lorne, Victoria (2003) [E3]

Co-authors: John Aitken

2003Asquith KL, Nixon B, Aitken RJ, 'Surface Localisation of Chaperone Proteins in Spermatozoa', 28th Annual Lorne Conference on Protein Structure & Function, Lorne, Victoria (2003) [E3]

Co-authors: John Aitken

2003Asquith KL, McLaughlin EA, Nixon B, Aitken RJ, 'Localisation of Tyrosine Phosphorylated Proteins on Mouse Spermatozoa during Zona Pellucida Interaction and Characterisation of Sperm Surface Phosphoproteins', Society for Reproductive Biology Proceedings of the Thirty-fourth Annual Conference, Melbourne (2003) [E3]
2003Nixon B, Clulow J, Ewen K, Krivanek K, Dacheux J-L, Jones RC, 'The avian epididymis: a model to study epididymal function?', Melbourne (2003) [E3]
2003Nixon B, Jones RC, Holland MK, 'Characterization of REP52, a rabbit epididymal secretory protein that interacts with the sperm tail', The Third International Conference on the Epididymis, Charlottesville, Virginia (2003) [E3]
1998Hollland MK, Nixon B, 'The specificity of epididymal secretory proteins', The Epididymis: Cellular and Molecular Aspects, Robertson, NSW Australia (1998) [E1]
1998Holland MK, Nixon B, 'The specificity of epididymal secretory proteins', JOURNAL OF REPRODUCTION AND FERTILITY, ROBERTSON, AUSTRALIA (1998)
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Grants and Funding

Summary

Number of grants42
Total funding$5,854,121

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2014 (6 grants)

Investigation of novel mechanisms for the regulation of sperm-oocyte interactions$882,232
Funding Body: ARC (Australian Research Council)

Project Team
Associate Professor Brett Nixon
SchemeRole
Future FellowshipsChief Investigator
Total AmountFunding StartFunding Finish
$882,23220142018
GNo:G1301259

miRNA regulation of sperm maturation $383,447
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Brett Nixon, Professor Eileen McLaughlin, Doctor Janet Holt
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$383,44720142016
GNo:G1300125

DVC(R) Research Support for Future Fellow (FT14)$60,000
Funding Body: University of Newcastle

Project Team
Associate Professor Brett Nixon
SchemeRole
Special Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$60,00020142017
GNo:G1400948

The Role of the GTPase Dynamin in the Female Germline$30,000
Funding Body: Hunter Medical Research Institute

Project Team
Ms Kate Redgrove, Doctor Janet Holt, Professor Eileen McLaughlin, Associate Professor Brett Nixon
SchemeRole
Bridging GrantInvestigator
Total AmountFunding StartFunding Finish
$30,00020142014
GNo:G1301333

The role of dynamin is spermatogenesis and sperm-oocyte interactions$20,000
Funding Body: University of Newcastle

Project Team
Associate Professor Brett Nixon, Professor Eileen McLaughlin, Professor Adam McCluskey
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$20,00020142014
GNo:G1301400

Development of contraception on demand $10,000
Funding Body: University of Newcastle

Project Team
Associate Professor Brett Nixon, Laureate Professor John Aitken
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00020142014
GNo:G1301399

2013 (6 grants)

Novel function of heat shock protein 2A in the regulation of human sperm-egg interactions$292,182
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Brett Nixon, Laureate Professor John Aitken, Professor Eileen McLaughlin
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$292,18220132015
GNo:G1200193

Leica TP 1020 Automatic Tissue Processor for histology applications$35,000
Funding Body: NHMRC (National Health & Medical Research Council)

Novel mechanisms for the regulation of sperm-oocyte interactions$20,000
Funding Body: University of Newcastle

Project Team
Associate Professor Brett Nixon
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$20,00020132013
GNo:G1300458

NucleoCounter SP100$14,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Laureate Professor John Aitken, Associate Professor Brett Nixon, Doctor Shaun Roman, Doctor Mark Baker, Doctor Geoffry De Iuliis, Doctor Lisa Mitchell, Doctor Matthew Jobling, Doctor Zamira Gibb, Mr Nenad Naumovski
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$14,00020132013
GNo:G1201175

Dynamin - role in sperm oocyte interaction$10,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Eileen McLaughlin, Associate Professor Brett Nixon, Professor Adam McCluskey
SchemeRole
Near MissInvestigator
Total AmountFunding StartFunding Finish
$10,00020132013
GNo:G1300700

Dynamin - role in sperm oocyte interaction$10,000
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin, Associate Professor Brett Nixon, Professor Adam McCluskey
SchemeRole
Near Miss GrantInvestigator
Total AmountFunding StartFunding Finish
$10,00020132013
GNo:G1300483

2012 (2 grants)

The role of miRNAs in the regulation of sperm maturation$10,000
Funding Body: University of Newcastle - Faculty of Science & IT

Project Team
Associate Professor Brett Nixon, Professor Eileen McLaughlin, Ms Natalie Beveridge
SchemeRole
Strategic Initiative Research Fund (SIRF)Chief Investigator
Total AmountFunding StartFunding Finish
$10,00020122012
GNo:G1401028

Faculty Visiting Fellowship 2012$7,447
Funding Body: University of Newcastle - Faculty of Science & IT

Project Team
Associate Professor Brett Nixon
SchemeRole
Visiting FellowshipChief Investigator
Total AmountFunding StartFunding Finish
$7,44720122012
GNo:G1401130

2011 (2 grants)

SLX4 - a key regulator of male germ cell development and DNA repair$25,000
Funding Body: Hunter Medical Research Institute

Project Team
Professor Eileen McLaughlin, Associate Professor Brett Nixon
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$25,00020112011
GNo:G1001000

Eppendorf mastercycler pro with thermomixer comfort and 5430R centrifuge$15,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Eileen McLaughlin, Professor Peter Lewis, Professor Adam McCluskey, Conjoint Professor Keith Jones, Associate Professor Brett Nixon, Doctor Shaun Roman, Doctor Jennette Sakoff, Doctor Ian Grainge, Doctor Janet Holt, Doctor Xiao Yang
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$15,00020112011
GNo:G1100028

2010 (6 grants)

An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$500,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Adam McCluskey, Laureate Professor John Aitken, Professor Paul Dastoor, Professor Phillip Robinson, Professor Eileen McLaughlin, Emeritus Professor Geoffrey Lawrance, Professor Marcel Maeder, Professor Hugh Dunstan, Doctor Shaun Roman, Associate Professor Rob Atkin, Doctor Clovia Holdsworth, Doctor Mark Baker, Doctor Nikki Verrills, Professor Gottfried Otting, Associate Professor Brett Nixon, Doctor Xiaojing Zhou, Ms Megan Chircop, Doctor Warwick Belcher
SchemeRole
Linkage Infrastructure Equipment & Facilities (LIEF)Investigator
Total AmountFunding StartFunding Finish
$500,00020102010
GNo:G0190402

Laser microdissection microscopy system for cell and development biology$350,000
Funding Body: ARC (Australian Research Council)

An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$280,000
Funding Body: University of Newcastle

Monotremes provide a key to understanding the molecular biology of mammalian gamete evolution$270,000
Funding Body: ARC (Australian Research Council)

Project Team
Associate Professor Brett Nixon, Dr Heath Ecroyd, Conjoint Associate Professor Russell Jones
SchemeRole
Discovery ProjectsChief Investigator
Total AmountFunding StartFunding Finish
$270,00020102012
GNo:G0190056

Laser microdissection microscopy system for cell and development biology$215,000
Funding Body: University of Newcastle

Waters, Ultra high performance liquid chromatography system (nano-Aquity) $30,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Mark Baker, Laureate Professor John Aitken, Professor Adam McCluskey, Associate Professor Brett Nixon, Emeritus Professor John Rostas, Professor Eileen McLaughlin
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$30,00020102010
GNo:G1000051

2009 (5 grants)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000
Funding Body: ARC (Australian Research Council)

Characterization of the molecular basis of human sperm-oocyte interaction$474,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Associate Professor Brett Nixon, Professor Eileen McLaughlin, Dr M O'Bryan
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$474,00020092011
GNo:G0188867

Confocal Laser Scanning Microscopy for Live Cell Imaging$275,000
Funding Body: ARC (Australian Research Council)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000
Funding Body: ARC (Australian Research Council)

LAS-4000 Chemiluminescence imaging system$25,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Eileen McLaughlin, Laureate Professor John Aitken, Professor Peter Lewis, Associate Professor Brett Nixon, Doctor Shaun Roman
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$25,00020092009
GNo:G0189852

2008 (4 grants)

Xenobiotics - ocidative stress in the mammalian ovary$362,625
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Eileen McLaughlin, Associate Professor Brett Nixon, Doctor Shaun Roman
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$362,62520082010
GNo:G0187620

Understanding the aetiology of human male infertility: Elucidation of the mechanisms underpinning sperm-egg interaction$21,650
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Brett Nixon, Professor Eileen McLaughlin
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$21,65020082008
GNo:G0188465

Characterization of the molecular basis of mouse sperm-oocyte interaction$18,285
Funding Body: University of Newcastle

Project Team
Associate Professor Brett Nixon, Professor Eileen McLaughlin
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$18,28520082008
GNo:G0188405

41st Annual Meeting of the Society for the Study of Reproduction $2,500
Funding Body: University of Newcastle

Project Team
Associate Professor Brett Nixon
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,50020082008
GNo:G0188643

2007 (4 grants)

Chemokines and spermatogenesis: roles of SDF-1 and CXCR-4 in the establishment of spermatogenesis$20,000
Funding Body: University of Newcastle

Project Team
Professor Eileen McLaughlin, Doctor Shaun Roman, Associate Professor Brett Nixon
SchemeRole
Near Miss GrantInvestigator
Total AmountFunding StartFunding Finish
$20,00020072007
GNo:G0187197

Determination of the molecular processes involved in post-testicular development of sperm in the platypus and their relationship with sperm competition$16,471
Funding Body: University of Newcastle

Project Team
Associate Professor Brett Nixon, Conjoint Associate Professor Russell Jones
SchemeRole
Near Miss GrantChief Investigator
Total AmountFunding StartFunding Finish
$16,47120072007
GNo:G0187188

Validation of novel model to explain the functional activation of mouse spermatozoa$7,998
Funding Body: University of Newcastle

Project Team
Associate Professor Brett Nixon
SchemeRole
Pilot GrantChief Investigator
Total AmountFunding StartFunding Finish
$7,99820072007
GNo:G0187878

Validation of novel model to explain the functional activation of mouse spermatozoa$7,002
Funding Body: University of Newcastle - Faculty of Science & IT

Project Team
Associate Professor Brett Nixon
SchemeRole
Pilot GrantChief Investigator
Total AmountFunding StartFunding Finish
$7,00220072007
GNo:G0188360

2006 (1 grants)

PRC - Priority Research Centre for Reproductive Science$544,282
Funding Body: University of Newcastle

Project Team
Laureate Professor John Aitken, Professor Roger Smith, Professor Eileen McLaughlin, Associate Professor Brett Nixon, Doctor Shaun Roman, Conjoint Associate Professor Vicki Clifton, Conjoint Professor Warwick Giles, Associate Professor Jon Hirst, Conjoint Associate Professor Rick Nicholson, Conjoint Professor Ian Symonds
SchemeRole
Priority Research CentreInvestigator
Total AmountFunding StartFunding Finish
$544,28220062013
GNo:G0186945

2005 (1 grants)

The initiation of fertilisation: Characterisation of the sperm receptor complex for the oocyte$9,000
Funding Body: University of Newcastle

Project Team
Associate Professor Brett Nixon, Laureate Professor John Aitken
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$9,00020052005
GNo:G0184742

2004 (3 grants)

Characterisation of a novel recepto-mediated signal transduction pathway in human spermatozoa.$14,000
Funding Body: University of Newcastle

Project Team
Associate Professor Brett Nixon, Emeritus Professor Leonie Ashman
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$14,00020042004
GNo:G0183444

Molecular basis of sperm-egg interaction: Identification of the receptor complex for ZP3$8,000
Funding Body: University of Newcastle

Project Team
Associate Professor Brett Nixon, Doctor Benjamin Curry
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$8,00020042004
GNo:G0183415

The role of the father in recurrent early pregnancy loss$7,000
Funding Body: Hunter Medical Research Institute

Project Team
Associate Professor Brett Nixon
SchemeRole
Adamstown Lions ClubChief Investigator
Total AmountFunding StartFunding Finish
$7,00020042004
GNo:G0183756

2002 (1 grants)

The role of protein tyrosine phosphorylation in mouse sperm-oocyte interaction$12,000
Funding Body: University of Newcastle

Project Team
Associate Professor Brett Nixon
SchemeRole
Early Career Researcher GrantChief Investigator
Total AmountFunding StartFunding Finish
$12,00020022002
GNo:G0182255

2001 (1 grants)

The role of protein tyrosine phosphorylation in mouse sperm-oocyte interaction$15,000
Funding Body: University of Newcastle

Project Team
Associate Professor Brett Nixon
SchemeRole
Early Career Researcher GrantChief Investigator
Total AmountFunding StartFunding Finish
$15,00020012001
GNo:G0180831
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Research Supervision

Number of current supervisions10
Total current UoN PhD EFTSL3.1

For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20142016PhD (Biological Sciences)Co-SupervisorIdentification of Novel Immunocontraceptive Targets for Fertility Control of Feral Horses
20142018PhD (Biological Sciences)Co-SupervisorDNA damage in the germ line
20142018PhD (Biological Sciences)Co-SupervisorAn Investigation of Equine Oocyte Maturation to Improve IVF and Embryo Retention Rates
20132017PhD (Biological Sciences)Co-SupervisorPhage Peptides Fertility Control
20132017PhD (Biological Sciences)Co-SupervisorInvestigation into the Molecular Composition of Spermatozoa to Determine Consequences in Human Reproduction
20132018PhD (Biological Sciences)Principal SupervisorPhage Display as a Tool for Investigation of the Molecular Mechanisms Underlying Mouse Sperm-Oolemma Interactions
20132017PhD (Biological Sciences)Co-SupervisorGenetic Consequences of Paternal Acrylamide Exposure and Potential for Amelioration
20122016PhD (Biological Sciences)Principal SupervisorThe Function of Molecular Chaperones in The Regulation of Human Sperm-Egg Interaction.
20122016PhD (Biological Sciences)Co-SupervisorCell Biology of Apoptosis in the Oocyte
20102014PhD (Biological Sciences)Principal SupervisorInvestigating Membrane Trafficking Proteins and Their Potential Role During Fertilisation

Past Supervision

YearProgramSupervisor TypeResearch Title
2014PhD (Biological Sciences)Co-SupervisorThe Consequences of Acrylamide Exposure of the Male Germ Line
2013PhD (Biological Sciences)Principal SupervisorNew Insights into the Molecular Basis of Human Sperm-Egg Interaction
2013PhD (Biological Sciences)Co-SupervisorRegulation of the Transition from Gonocytes to Spermatogonia
2012PhD (Biological Sciences)Principal SupervisorThe Molecular Basis of Sperm - Oocyte Interactions
2012PhD (Biological Sciences)Co-SupervisorXenobiotics; Effects on Female Fertility
2010PhD (Biological Sciences)Co-SupervisorSignificance of Mitochondrial Reactive Oxygen Species Production in Male Infertility
2009PhD (Biological Sciences)Co-SupervisorThe Molecular Basis of Human Sperm-Zona Pellucida Interaction
2007M Philosophy (Biological Sc)Co-SupervisorIdentification of NADPH Oxidase in Mouse Spermatozoa
2007PhD (Biological Sciences)Co-SupervisorThe Development of a Novel Electrophoretic System for the Isolation of Human Spermatozoa
2005PhD (Biological Sciences)Co-SupervisorThe Molecular Basis of Sperm-Oocyte Interaction in the Mouse
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Associate Professor Brett Nixon

Work Phone(02) 4921 6977
Fax(02) 4921 6923
Email
PositionAssociate Professor
School of Environmental and Life Sciences
Faculty of Science and Information Technology
The University of Newcastle, Australia
Focus AreaBiological Sciences
Office
LS4-40,
Life Sciences,
Callaghan
University Drive
Callaghan NSW 2308
Australia
URL:www.newcastle.edu.au/profile/brett-nixon