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Associate Professor Brett Nixon

ARC Future Fellow

School of Environmental and Life Sciences (Biological Sciences)

Career Summary

Biography

I obtained my PhD from the University of Newcastle (awarded 1999) working on a collaborative project with the Vertebrate Biocontrol Cooperative Research Centre focused on characterising protein expression and function in male gametogenesis. This work helped to define to role of the male reproductive tract in post-testicular sperm maturation. I then undertook post-doctoral research in the Department of Cell Biology, Emory University, GA, USA (1999-2000). This work centred on the characterisation of a knockout mouse model bearing a targeted deletion of a key protein involved in gamete interactions. In 2001, I was recruited to the University of Newcastle as an Associate Lecturer in Biological Sciences and promoted to the position of Lecturer in 2004, Senior Lecturer in 2007, and Associate Professor in 2011. Since appointment I have established an active research program focusing on the use of human and animal models to characterise the processes of gamete maturation. In spermatozoa, I am currently working on a number of key molecules that control cell function and regulate gamete interactions. In folliculogenesis, I have focused on cell signalling pathways that contribute to the initiation of primordial follicle activation and the effects of environmental ovotoxicants on these pathways.

Research Expertise

I obtained my PhD from the University of Newcastle (awarded 1999) working on a collaborative project with the Vertebrate Biocontrol CRC focused on characterising protein expression and function in male gametogenesis. This work helped to define to role of the male reproductive tract in post-testicular sperm maturation. I then undertook post-doctoral research in the Department of Cell Biology, Emory University, GA, USA (1999-2000). This work centred on the characterisation of a knockout mouse model bearing a targeted deletion of a key protein involved in gamete interactions. In 2001, I was recruited to the University of Newcastle as an Associate Lecturer in Biological Sciences and promoted to the position of Lecturer in 2004, Senior Lecturer in 2007, and Associate Professor in 2011. Since appointment I have established an active research program focusing on the use of human and animal models to characterise the processes of gamete maturation. In spermatozoa, I am working on a number of projects with the overriding goal of elucidating the molecular mechanisms that govern sperm activation and regulate gamete interactions. In folliculogenesis, I have focussed on cell signalling pathways that contribute to the initiation of primordial follicle activation and the effects of environmental ovotoxicants. These projects are of strategic importance in the design of post-testicular methods of fertility regulation, the development of assisted conception systems for the preservation of endangered species and elucidation of the causes of human male infertility. My research niche complements existing programs in male germ cell development and ovarian biology within the Reproductive Science Group at the University of Newcastle. It also represents a strategically important subprogram of the University’s Priority Research Centre (PRC) for Reproductive Science. Furthermore, my research encompasses the National Research Priority goals of (i) safeguarding Australia (protecting Australia from invasive diseases and pests) and (ii) promoting and maintaining good health (a healthy start to life).

Teaching Expertise
Undergraduate Teaching Since my appointment in 2001, I have made a significant and sustained contribution to the teaching effort of the Discipline of Biological Sciences through the delivery of lectures and supervision of practical classes and tutorials across a broad range of courses (Levels 1000 – 4000). I strive for excellence in teaching and generate consistently high SEC and SET evaluations and qualitative feedback. My current teaching commitment includes: BIOL1001 Cells, Molecules, and Organisms BIOL1001 Gifted and Talented Program (Course coordinator) BIOL2001 Molecular Laboratory Skills for Biological Sciences BIOL2010 Biochemistry (Course coordinator) BIOL2050 Molecular Genetics BIOL3200 Cellular Biotechnology BIOL3250 Biotechnology Placement BIOL4110 - BIOL4220 BSc (Biology) Honours / BBiotech Honours (Program coordinator) Research Training Since 2001, I have supervised 6 PhD, 1 MPhil and 13 Honours students to successful completion of their research higher degrees. I am currently the principal supervisor of 3 PhD and 1 Honours student and the co-supervisor of an additional 3 PhD students. My commitment to research training is evidenced by the recent award of RHD Supervisor of the Year (2009), the University of Newcastle’s highest accolade for student supervision. The quality of my students is attested by the award of numerous platform and poster prizes at national and international meetings, including: best student poster at Lorne Protein (2003), Oozoa award for best student oral presentation at the Society for Reproduction (SRB) annual meeting (2008 & 2010), best student poster at the Australian Society for Biochemistry and Molecular Biology annual meeting (2010), best student poster at the International Symposium on Spermatology (Japan, 2010), and the SRB - New Investigator award (2011).

Administrative Expertise
Service to the University I am dedicated to building achievements in relation to University, Community and Professional Service. Since appointment to my current position I have made a significant commitment to University Service and related professional activities. Specifically, I focused on initiatives that enrich the student learning experience and promote a vibrant research culture, thus contributing to the status of the University's teaching and research profile. My committee membership aligns with my recognised strengths in teaching and research, and has included: Assistant Dean Teaching and Learning, Faculty of Science and IT Student Recruitment Committee, Faculty of Science and IT Honours Committee Chair, School of Environmental and Life Sciences Postgraduate Committee, Discipline of Biological Sciences Analytical and Biomolecular Research Facility Advisory Committee OH&S Committee, Reproductive Sciences Group Service to the profession Elected member of Council / Chair of Awards Committee for Society for Reproductive Biology (2014 - ongoing) Member of Grant Review Panel for Reproductive Medicine, Obstetrics & Gynaecology, and Paediatrics, National Health and Medical Research Council of Australia (2013-ongoing) Associate Editor, Molecular Human Reproduction (ranked 3/28 in Reproductive Biology) (2011 - ongoing) I review for a number of grant bodies such as NHMRC and Medical Research Council (UK). I also review for 20 specialist journals including Reproduction, Biology of Reproduction, Human Reproduction, Developmental Biology (~20 manuscripts/year).

Collaborations
I have collaborative partnerships with a number of pre-eminent national and international scientists within the field of gamete biology. Similarly, I have established collaborations with IVF clinics to support the extension of my research program into the clinical domain. This nexus is critical for our ability to drive translational outcomes in understanding the aetiology of human male infertility.

Qualifications

  • PhD, University of Newcastle
  • Bachelor of Science (Honours), University of Newcastle
  • Bachelor of Science, University of Newcastle

Keywords

  • Biology
  • Reproductive Biology

Fields of Research

Code Description Percentage
060899 Zoology not elsewhere classified 15
111499 Paediatrics and Reproductive Medicine not elsewhere classified 50
060199 Biochemistry and Cell Biology not elsewhere classified 35

Professional Experience

UON Appointment

Title Organisation / Department
Associate Professor University of Newcastle
School of Environmental and Life Sciences
Australia

Academic appointment

Dates Title Organisation / Department
1/01/2015 -  Fellow ARC (Australian Research Council)
1/01/2013 -  Elected member of Council / Chair of Awards Committee Society for Reproductive Biology
Australia
1/07/2011 -  Associate Professor University of Newcastle
School of Environmental and Life Sciences
Australia
1/01/2011 -  Editor - Molecular Human Reproduction Molecular Human Reproduction Journal
Australia
1/01/2008 -  Membership - Society for the Study of Reproduction Society for the Study of Reproduction
Australia
1/01/2008 - 1/06/2011 Senior Lecturer University of Newcastle
School of Environmental and Life Sciences
Australia
1/01/2004 - 1/01/2008 Lecturer University of Newcastle
School of Environmental and Life Sciences
Australia
1/01/2001 - 1/01/2004 Associate Lecturer University of Newcastle
School of Environmental and Life Sciences
Australia
1/01/1999 - 1/12/2000 NIH Post-Doctoral Research Fellow Emory University, School of Medicine, Atlanta, GA
Department of Cell Biology
United States
1/01/1997 -  Membership - Society for Reproductive Biology Society for Reproductive Biology
Australia

Awards

Distinction

Year Award
2013 Vice-Chancellor’s Award for Teaching Excellence and Learning Support
University of Newcastle
2013 Vice-Chancellor’s citation for outstanding contributions to student learning
University of Newcastle
2009 Faculty of Science and IT Research Higher Degree Supervisor of the Year
Unknown
2009 The University of Newcastle Supervisor of the Year
Unknown

Recipient

Year Award
2014 Citation for Outstanding Contributions to Student Learning
Office for Learning and Teaching

Recognition

Year Award
2011 Certificate of Recognition for excellent contribution to peer review
Unknown
1998 Finalist, Junior Scientist Competition
Unknown

Research Award

Year Award
2012 Award for Excellence in Reproductive Biology Research
Society for Reproductive Biology
2007 New Investigator Grant
Hunter Medical Research Institute
2006 Lalor Foundation Award
Unknown
1998 Student Travel Grant
Unknown

Invitations

Participant

Year Title / Rationale
2007 The Biology of Extracellular Molecular Chaperones
Organisation: Novartis Foundation
Edit

Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (3 outputs)

Year Citation Altmetrics Link
2012 Redgrove KA, Aitken RJ, Nixon B, 'More than a simple lock and key mechanism: unraveling the intricacies of sperm-oocyte interactions', Binding Protein, InTech, Rijeka, Croatia 73-122 (2012) [B1]
DOI 10.5772/2897
Co-authors John Aitken
2010 Aitken RJ, Baker MA, De Iuliis GN, Nixon B, 'New insights into sperm physiology and pathology', Fertility Control, Springer, Berlin 99-115 (2010) [B1]
Citations Scopus - 23
Co-authors Mark Baker, Geoffry DeiuliIs, John Aitken
2010 Dun MD, Mitchell LA, Aitken RJ, Nixon B, 'Sperm-zona pellucida interaction: Molecular mechanisms and the potential for contraceptive intervention', Fertility Control, Springer, Berlin 139-178 (2010) [B1]
Citations Scopus - 4
Co-authors John Aitken, Matt Dun

Journal article (68 outputs)

Year Citation Altmetrics Link
2015 Bromfield E, Aitken RJ, Nixon B, 'Novel characterization of the HSPA2-stabilizing protein BAG6 in human spermatozoa.', Mol Hum Reprod, (2015)
DOI 10.1093/molehr/gav041
Co-authors John Aitken
2015 Nixon B, Bromfield EG, Dun MD, Redgrove KA, McLaughlin EA, Aitken RJ, 'The role of the molecular chaperone heat shock protein A2 (HSPA2) in regulating human sperm-egg recognition.', Asian J Androl, 17 568-573 (2015)
DOI 10.4103/1008-682X.151395
Co-authors Eileen Mclaughlin, Matt Dun, John Aitken
2015 Aitken RJ, Cummins JM, Nixon B, 'The 12 (th) International Symposium on Spermatology.', Asian J Androl, 17 519-520 (2015)
DOI 10.4103/1008-682X.153852
Co-authors John Aitken
2015 Aitken RJ, Baker MA, Nixon B, 'Are sperm capacitation and apoptosis the opposite ends of a continuum driven by oxidative stress?', Asian J Androl, 17 633-639 (2015)
DOI 10.4103/1008-682X.153850
Co-authors John Aitken, Mark Baker
2015 Reid AT, Anderson AL, Roman SD, McLaughlin EA, McCluskey A, Robinson PJ, et al., 'Glycogen synthase kinase 3 regulates acrosomal exocytosis in mouse spermatozoa via dynamin phosphorylation.', FASEB J, 29 2872-2882 (2015)
DOI 10.1096/fj.14-265553
Co-authors Adam Mccluskey, John Aitken, Eileen Mclaughlin, Shaun Roman
2015 Nixon B, Stanger SJ, Mihalas BP, Reilly JN, Anderson AL, Dun MD, et al., 'Next Generation Sequencing Analysis Reveals Segmental Patterns of microRNA Expression in Mouse Epididymal Epithelial Cells.', PloS one, 10 e0135605 (2015)
DOI 10.1371/journal.pone.0135605
Co-authors Eileen Mclaughlin, Matt Dun
2014 Nixon BJ, Katen AL, Stanger SJ, Schjenken JE, Nixon B, Roman SD, 'Mouse spermatocytes express CYP2E1 and respond to acrylamide exposure', PLoS ONE, 9 (2014) [C1]

Metabolism of xenobiotics by cytochrome P450s (encoded by the CYP genes) often leads to bio-activation, producing reactive metabolites that interfere with cellular processes and c... [more]

Metabolism of xenobiotics by cytochrome P450s (encoded by the CYP genes) often leads to bio-activation, producing reactive metabolites that interfere with cellular processes and cause DNA damage. In the testes, DNA damage induced by xenobiotics has been associated with impaired spermatogenesis and adverse effects on reproductive health. We previously reported that chronic exposure to the reproductive toxicant, acrylamide, produced high levels of DNA damage in spermatocytes of Swiss mice. CYP2E1 metabolises acrylamide to glycidamide, which, unlike acrylamide, readily forms adducts with DNA. Thus, to investigate the mechanisms of acrylamide toxicity in mouse male germ cells, we examined the expression of the CYP, CYP2E1, which metabolises acrylamide. Using Q-PCR and immunohistochemistry, we establish that CYP2E1 is expressed in germ cells, in particular in spermatocytes. Additionally, CYP2E1 gene expression was upregulated in these cells following in vitro acrylamide exposure (1 µM, 18 h). Spermatocytes were isolated and treated with 1 µM acrylamide or 0.5 µM glycidamide for 18 hours and the presence of DNA-adducts was investigated using the comet assay, modified to detect DNA-adducts. Both compounds produced significant levels of DNA damage in spermatocytes, with a greater response observed following glycidamide exposure. A modified comet assay indicated that direct adduction of DNA by glycidamide was a major source of DNA damage. Oxidative stress played a small role in eliciting this damage, as a relatively modest effect was found in a comet assay modified to detect oxidative adducts following glycidamide exposure, and glutathione levels remained unchanged following treatment with either compound. Our results indicate that the male germ line has the capacity to respond to xenobiotic exposure by inducing detoxifying enzymes, and the DNA damage elicited by acrylamide in male germ cells is likely due to the formation of glycidamide adducts. © 2014 Nixon et al.

DOI 10.1371/journal.pone.0094904
Citations Scopus - 1
Co-authors Shaun Roman
2014 Bromfield EG, Aitken RJ, Gibb Z, Lambourne SR, Nixon B, 'Capacitation in the presence of methyl-beta-cyclodextrin results in enhanced zona pellucida-binding ability of stallion spermatozoa', REPRODUCTION, 147 153-166 (2014) [C1]
DOI 10.1530/REP-13-0393
Citations Scopus - 2Web of Science - 2
Co-authors Zamira Gibb, John Aitken
2014 Nixon B, Ewen KA, Krivanek KM, Clulow J, Kidd G, Ecroyd H, Jones RC, 'Post-testicular sperm maturation and identification of an epididymal protein in the Japanese quail (Coturnix coturnix japonica)', REPRODUCTION, 147 265-277 (2014) [C1]
DOI 10.1530/REP-13-0566
Citations Web of Science - 1
Co-authors John Clulow
2013 McIver SC, Roman SD, Nixon B, McLaughlin EA, Loveland KL, 'The rise of testicular germ cell tumours: The search for causes, risk factors and novel therapeutic targets [v1; ref status: Indexed, http://f1000r.es/md]', F1000 Research, 2 1-12 (2013) [C1]
DOI 10.12688/f1000research.2-55.v2
Co-authors Shaun Roman, Eileen Mclaughlin
2013 McIver SM, Roman SD, Nixon B, Loveland KL, McLaughlin EA, 'The rise of testicular germ cell tumours: the search for causes, risk factors and novel therapeutic targets', F1000Research, 2:55 (doi: 10.12688/f1000research.2-55.v1) 55-66 (2013)
Citations Scopus - 2
Co-authors Eileen Mclaughlin, Shaun Roman
2013 Lord T, Nixon B, Jones KT, Aitken RJ, 'Melatonin Prevents Postovulatory Oocyte Aging in the Mouse and Extends the Window for Optimal Fertilization In Vitro', Biology of Reproduction, 88 1-9 (2013) [C1]
DOI 10.1095/biolreprod.112.106450
Citations Scopus - 9Web of Science - 6
Co-authors John Aitken, Keith Jones
2013 Redgrove KA, Anderson AL, McLaughlin EA, O'Bryan MK, Aitken RJ, Nixon B, 'Investigation of the mechanisms by which the molecular chaperone HSPA2 regulates the expression of sperm surface receptors involved in human spermoocyte recognition', MOLECULAR HUMAN REPRODUCTION, 19 120-135 (2013) [C1]
DOI 10.1093/molehr/gas064
Citations Scopus - 15Web of Science - 16
Co-authors John Aitken, Eileen Mclaughlin
2013 Aitken RJ, Nixon B, 'Sperm capacitation: a distant landscape glimpsed but unexplored', Molecular Human Reproduction, 19 785-793 (2013) [C1]
DOI 10.1093/molehr/gat067
Citations Scopus - 12Web of Science - 13
Co-authors John Aitken
2013 Bromfield EG, Nixon B, 'The function of chaperone proteins in the assemblage of protein complexes involved in gamete adhesion and fusion processes', Reproduction, 145 R31-R42 (2013) [C1]
DOI 10.1530/REP-12-0316
Citations Scopus - 8Web of Science - 7
2013 McIver SC, Loveland KL, Roman SD, Nixon B, Kitazawa R, McLaughlin EA, 'The chemokine CXCL12 and its receptor CXCR4 are implicated in human seminoma metastasis', ANDROLOGY, 1 517-529 (2013) [C1]
DOI 10.1111/j.2047-2927.2013.00081.x
Citations Scopus - 8Web of Science - 9
Co-authors Eileen Mclaughlin, Shaun Roman
2012 Reid AT, Lord T, Stanger SJ, Roman SD, McCluskey A, Robinson PJ, et al., 'Dynamin regulates specific membrane fusion events necessary for acrosomal exocytosis in mouse spermatozoa', Journal of Biological Chemistry, 287 37659-37672 (2012) [C1]
Citations Scopus - 10Web of Science - 10
Co-authors Shaun Roman, John Aitken, Adam Mccluskey
2012 Sutherland JM, Keightley RA, Nixon B, Roman SD, Robker RL, Russell DL, McLaughlin EA, 'Suppressor of cytokine signaling 4 (SOCS4): Moderator of ovarian primordial follicle activation', Journal of Cellular Physiology, 227 1188-1198 (2012) [C1]
Citations Scopus - 9Web of Science - 7
Co-authors Eileen Mclaughlin, Shaun Roman
2012 Sobinoff AP, Pye VJ, Nixon B, Roman SD, McLaughlin EA, 'Jumping the gun: Smoking constituent BaP causes premature primordial follicle activation and impairs oocyte fusibility through oxidative stress', Toxicology and Applied Pharmacology, 260 70-80 (2012) [C1]
Citations Scopus - 22Web of Science - 19
Co-authors Eileen Mclaughlin, Shaun Roman
2012 Dun MD, Anderson AL, Bromfield EG, Asquith KL, Emmett BJ, McLaughlin EA, et al., 'Investigation of the expression and functional significance of the novel mouse sperm protein, a disintegrin and metalloprotease with thrombospondin type 1 motifs number 10 (ADAMTS10)', International Journal of Andrology, 35 572-589 (2012) [C1]
DOI 10.1111/j.1365-2605.2011.01235.x
Citations Scopus - 6Web of Science - 6
Co-authors Matt Dun, John Aitken, Eileen Mclaughlin
2012 Sobinoff AP, Nixon B, Roman SD, McLaughlin EA, 'Staying alive: PI3K pathway promotes primordial follicle activation and survival in response to 3MC-induced ovotoxicity', Toxicological Sciences, 128 258-271 (2012) [C1]
Citations Scopus - 15Web of Science - 14
Co-authors Shaun Roman, Eileen Mclaughlin
2012 Nixon BJ, Stanger SJ, Nixon B, Roman SD, 'Chronic exposure to acrylamide induces DNA damage in male germ cells of mice', Toxicological Sciences, 129 135-145 (2012) [C1]
Citations Scopus - 10Web of Science - 9
Co-authors Shaun Roman
2012 McIver SC, Roman SD, Nixon B, McLaughlin EA, 'miRNA and mammalian male germ cells', Human Reproduction Update, 18 44-59 (2012) [C1]
Citations Scopus - 41Web of Science - 38
Co-authors Eileen Mclaughlin, Shaun Roman
2012 Dun MD, Aitken RJ, Nixon B, 'The role of molecular chaperones in spermatogenesis and the post-testicular maturation of mammalian spermatozoa', Human Reproduction Update, 18 420-435 (2012) [C1]
DOI 10.1093/humupd/dms009
Citations Scopus - 12Web of Science - 11
Co-authors Matt Dun, John Aitken
2012 McIver SC, Stanger SJ, Santarelli DMF, Roman SD, Nixon B, McLaughlin EA, 'A unique combination of male germ cell mirnas coordinates gonocyte differentiation', PLoS One, 7 1-14 (2012) [C1]
Citations Scopus - 20Web of Science - 15
Co-authors Eileen Mclaughlin, Shaun Roman
2012 Redgrove KA, Nixon B, Baker MA, Hetherington L, Baker G, Liu D-Y, Aitken RJ, 'The molecular chaperone HSPA2 plays a key role in regulating the expression of sperm surface receptors that mediate sperm-egg recognition', Plos One, 7 1-16 (2012) [C1]
Citations Scopus - 20Web of Science - 21
Co-authors Mark Baker, John Aitken
2012 Baker MA, Nixon B, Naumovski N, Aitken RJ, 'Proteomic insights into the maturation and capacitation of mammalian spermatozoa', Systems Biology in Reproductive Medicine, 58 211-217 (2012) [C1]
DOI 10.3109/19396368.2011.639844
Citations Scopus - 22Web of Science - 20
Co-authors Mark Baker, John Aitken
2011 Redgrove KA, Anderson AL, Dun MD, McLaughlin EA, O'Bryan MK, Aitken RJ, Nixon B, 'Involvement of multimeric protein complexes in mediating the capacitation-dependent binding of human spermatozoa to homologous zonae pellucidae', Developmental Biology, 356 460-474 (2011) [C1]
DOI 10.1016/j.ydbio.2011.05.674
Citations Scopus - 21Web of Science - 25
Co-authors Eileen Mclaughlin, John Aitken, Matt Dun
2011 Dun MD, Smith ND, Baker MA, Lin M, Aitken RJ, Nixon B, 'The chaperonin containing TCP1 complex (CCT/TRiC) is involved in mediating sperm-oocyte interaction', Journal of Biological Chemistry, 286 36875-36887 (2011) [C1]
DOI 10.1074/jbc.m110.188888
Citations Scopus - 21Web of Science - 20
Co-authors Mark Baker, Minjie Lin, John Aitken, Matt Dun
2011 Nixon B, Mitchell LA, Anderson AL, McLaughlin EA, O'Bryan MK, Aitken RJ, 'Proteomic and functional analysis of human sperm detergent resistant membranes', Journal of Cellular Physiology, 226 2651-2665 (2011) [C1]
DOI 10.1002/jcp.22615
Citations Scopus - 31Web of Science - 31
Co-authors Eileen Mclaughlin, John Aitken
2011 Ainsworth CJ, Nixon B, Aitken RJ, 'The electrophoretic separation of spermatozoa: An analysis of genotype, surface carbohydrate composition and potential for capacitation', International Journal of Andrology, 34 e422-e434 (2011) [C1]
DOI 10.1111/j.1365-2605.2011.01164.x
Citations Scopus - 9Web of Science - 3
Co-authors John Aitken
2011 Nixon B, Ecroyd HW, Dacheux J-L, Jones RC, 'Monotremes provide a key to understanding the evolutionary significance of epididymal sperm maturation', Journal of Andrology, 32 665-671 (2011) [C1]
DOI 10.2164/jandrol.110.012716
Citations Scopus - 1Web of Science - 1
2011 Sobinoff AP, Mahony M, Nixon B, Roman SD, McLaughlin EA, 'Understanding the villain: DMBA-induced preantral ovotoxicity involves selective follicular destruction and primordial follicle activation through PI3K/Akt and mTOR signaling', Toxicological Sciences, 123 563-575 (2011) [C1]
Citations Scopus - 21Web of Science - 20
Co-authors Shaun Roman, Eileen Mclaughlin
2010 Gibbs GM, Lo JCY, Nixon B, Jamsai D, O'Connor AE, Rijal S, et al., 'Glioma pathogenesis-related 1-Like 1 is testis enriched, dynamically modified, and redistributed during male germ cell maturation and has a potential role in sperm-oocyte binding', Endocrinology, 151 2331-2342 (2010) [C1]
DOI 10.1210/en.2009-1255
Citations Scopus - 17Web of Science - 15
2010 Reid AT, Redgrove KA, Aitken RJ, Nixon B, 'Cellular mechanisms regulating sperm-zona pellucida interaction', Asian Journal of Andrology, 13 88-96 (2010) [C1]
DOI 10.1038/aja.2010.74
Citations Scopus - 24Web of Science - 24
Co-authors John Aitken
2010 Sobinoff AP, Pye VJ, Nixon B, Roman SD, McLaughlin EA, 'Adding insult to injury: Effects of xenobiotic-induced preantral ovotoxicity on ovarian development and oocyte fusibility', Toxicological Sciences, 118 653-666 (2010) [C1]
DOI 10.1093/toxsci/kfq272
Citations Scopus - 17Web of Science - 17
Co-authors Shaun Roman, Eileen Mclaughlin
2010 Nixon B, Bielanowicz AJ, Anderson AL, Walsh AK, Hall TE, McCloghry AK, Aitken RJ, 'Elucidation of the signaling pathways that underpin capacitation-associated surface phosphotyrosine expression in mouse spermatozoa', Journal of Cellular Physiology, 224 71-83 (2010) [C1]
DOI 10.1002/jcp.22090
Citations Scopus - 16Web of Science - 15
Co-authors John Aitken
2009 Nixon B, Aitken RJ, 'Proteomics of human spermatozoa 3-12 (2009)
DOI 10.1007/978-3-642-01379-9
Co-authors John Aitken
2009 De Iuliis GN, Thomson LK, Mitchell LA, Read JM, Koppers AJ, Hedges A, et al., 'DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2'-deoxyguanosine, a marker of oxidative stress', Biology of Reproduction, 81 517-524 (2009) [C1]
DOI 10.1095/biolreprod.109.076836
Citations Scopus - 120Web of Science - 114
Co-authors Geoffry DeiuliIs, John Aitken
2009 Nixon B, Bielanowicz AJ, McLaughlin EA, Tanphaichitr N, Ensslin MA, Aitken RJ, 'Composition and significance of detergent resistant membranes in mouse spermatozoa', Journal of Cellular Physiology, 218 122-134 (2009) [C1]
DOI 10.1002/jcp.21575
Citations Scopus - 60Web of Science - 59
Co-authors John Aitken, Eileen Mclaughlin
2009 Bennetts LE, De Iuliis GN, Nixon B, Kime M, Zelski K, McVicar CM, et al., 'Impact of estrogenic compounds on DNA integrity in human spermatozoa: Evidence for cross-linking and redox cycling activities', Journal of Urology, 181 914-915 (2009) [C3]
DOI 10.1016/j.mrfmmm.2008.02.002
Citations Scopus - 46
Co-authors Geoffry DeiuliIs, John Aitken
2009 Nixon B, Aitken RJ, 'The biological significance of detergent-resistant membranes in spermatozoa', Journal of Reproductive Immunology, 83 8-13 (2009) [C1]
DOI 10.1016/j.jri.2009.06.258
Citations Scopus - 24Web of Science - 22
Co-authors John Aitken
2009 Dacheux J-L, Dacheux F, Labas V, Ecroyd H, Nixon B, Jones RC, 'New proteins identified in epididymal fluid from the platypus (Ornithorhynchus anatinus)', Reproduction Fertility and Development, 21 1002-1007 (2009) [C1]
DOI 10.1071/rd09091
Citations Scopus - 5Web of Science - 5
2009 Ecroyd H, Nixon B, Dacheux J-L, Jones RC, 'Testicular descent, sperm maturation and capacitation: Lessons from our most distant relatives, the monotremes', Reproduction Fertility and Development, 21 992-1001 (2009) [C1]
DOI 10.1071/rd09081
Citations Scopus - 2Web of Science - 2
2008 Mitchell LA, Nixon B, Baker MA, Aitken RJ, 'Investigation of the role of SRC in capacitation-associated tyrosine phosphorylation of human spermatozoa', Molecular Human Reproduction, 14 235-243 (2008) [C1]
DOI 10.1093/molehr/gan007
Citations Scopus - 46Web of Science - 46
Co-authors Mark Baker, John Aitken
2008 Bennetts LE, De Iuliis GN, Nixon B, Kime M, Nixon K, McVicar CM, et al., 'Impact of estrogenic compounds on DNA integrity in human spermatozoa: Evidence for cross-linking and redox cycling activities', Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 641 1-11 (2008) [C1]
DOI 10.1016/j.mrfmmm.2008.02.002
Citations Web of Science - 44
Co-authors John Aitken, Geoffry DeiuliIs
2008 Grutzner F, Nixon B, Jones RC, 'Reproductive biology in egg-laying mammals', Sexual Development, 2 115-127 (2008) [C1]
DOI 10.1159/000143429
Citations Scopus - 8Web of Science - 9
2008 Nixon B, Jones RC, Holland MK, 'Molecular and functional characterization of the rabbit epididymal secretory protein 52, REP52', Biology of Reproduction, 78 910-920 (2008) [C1]
DOI 10.1095/biolreprod.107.065524
Citations Scopus - 2Web of Science - 2
2008 Walsh AK, Whelan D, Bielanowicz AJ, Skinner BL, Aitken RJ, O'Bryan MK, Nixon B, 'Identification of the molecular chaperone, heat shock protein 1 (chaperonin 10), in the reproductive tract and in capacitating spermatozoa in the male mouse', Biology of Reproduction, 78 983-993 (2008) [C1]
DOI 10.1095/biolreprod.107.066860
Citations Scopus - 27Web of Science - 25
Co-authors John Aitken
2008 Warren WC, Hillier LW, Graves JAM, Birney E, Ponting CP, Grutzner F, et al., 'Genome analysis of the platypus reveals unique signatures of evolution (vol 453, pg 175, 2008)', NATURE, 455 256-256 (2008) [C3]
DOI 10.1038/nature07253
Citations Web of Science - 5
2008 Warren WC, Hillier LW, Graves JAM, Birney E, Ponting CP, Grutzner F, et al., 'Genome analysis of the platypus reveals unique signatures of evolution', Nature, 453 175-U1 (2008) [C1]
DOI 10.1038/nature06936
Citations Scopus - 351Web of Science - 341
2008 Priestley MN, Dunstan RH, O'Connor WA, Van Zwieten L, Nixon B, Macfarlane GR, 'Effects of 4-nonylphenol and 17 alpha-ethynylestradiol exposure in the Sydney rock oyster, Saccostrea glomerata: Vitellogenin induction and gonadal development', Aquatic Toxicology, 88 39-47 (2008) [C1]
DOI 10.1016/j.aquatox.2008.03.003
Citations Scopus - 35Web of Science - 31
Co-authors Hugh Dunstan, Geoff Macfarlane
2007 Aitken RJ, Nixon B, Lin M, Koppers AJ, Lee YH, Baker MA, 'Proteomic changes in mammalian spermatozoa during epididymal maturation', Asian Journal of Andrology, 9 554-564 (2007) [C1]
DOI 10.1111/j.1745-7262.2007.00280.x
Citations Scopus - 71Web of Science - 63
Co-authors Minjie Lin, John Aitken, Mark Baker
2007 Jones RC, Dacheux JL, Nixon B, Ecroyd HW, 'Role of the epididymis in sperm competition', Asian Journal of Andrology, 9 493-499 (2007) [C1]
DOI 10.1111/j.1745-7262.2007.00284.x
Citations Scopus - 13Web of Science - 14
2007 Mitchell LA, Nixon B, Aitken RJ, 'Analysis of chaperone proteins associated with human spermatozoa during capacitation', Molecular Human Reproduction, 13 605-613 (2007) [C1]
DOI 10.1093/molehr/gam043
Citations Scopus - 39Web of Science - 38
Co-authors John Aitken
2007 Nixon B, Aitken RJ, McLaughlin EA, 'New insights into the molecular mechanisms of sperm-egg interaction', Cellular and Molecular Life Sciences, 64 1805-1823 (2007) [C1]
DOI 10.1007/s00018-007-6552-x
Co-authors John Aitken, Eileen Mclaughlin
2007 Ainsworth CJ, Nixon B, Jansen RPS, Aitken RJ, 'First recorded pregnancy and normal birth after ICSI using electrophoretically isolated spermatozoa', Human Reproduction, 22 197-200 (2007) [C1]
DOI 10.1093/humrep/del351
Citations Scopus - 40Web of Science - 35
Co-authors John Aitken
2006 Nixon B, Macintyre DA, Mitchell LA, Gibbs GM, O'Bryan M, Aitken RJ, 'The identification of mouse sperm-surface-associated proteins and characterization of their ability to act as decapacitation factors', Biology of Reproduction, 74 275-287 (2006) [C1]
DOI 10.1095/biolreprod.105.044644
Citations Scopus - 70Web of Science - 72
Co-authors John Aitken
2005 Nixon B, Paul JW, Spiller CM, Attwell-Heap AG, Ashman LK, Aitken RJ, 'Evidence for the involvement of PECAM-1 in a receptor mediated signal-transduction pathway regulating capacitation-associated tyrosine phosphorylation in human spermatozoa', Journal of Cell Science, 118 4865-4877 (2005) [C1]
DOI 10.1242/jcs.02604
Citations Scopus - 13Web of Science - 13
Co-authors John Aitken, Leonie Ashman, Jonathan Paul
2005 Nixon B, Asquith KL, Aitken RJ, 'The role of molecular chaperones in mouse sperm-egg interactions', Molecular and Cellular Endocrinology, 240 1-10 (2005) [C1]
DOI 10.1016/j.mce.2005.06.004
Citations Scopus - 20Web of Science - 16
Co-authors John Aitken
2004 Asquith KL, Baleato R, McLaughlin EA, Nixon B, Aitken RJ, 'Tyrosine phosphorylation activates surface chaperones facilitating sperm-zona recognition', Journal of Cell Science, 117 3645-3657 (2004) [C1]
DOI 10.1242/jcs.01214
Citations Scopus - 105Web of Science - 97
Co-authors John Aitken, Eileen Mclaughlin
2004 Curry BJ, Su H, Law EG, McLaughlin EA, Nixon B, Aitken RJ, 'Identification of RARhoGAP, a novel putative RhoGAP gene expressed in male germ cells', Genomics, 84 406-418 (2004) [C1]
DOI 10.1016/j.ygeno.2004.03.004
Citations Scopus - 9Web of Science - 10
Co-authors Ben Curry, Eileen Mclaughlin, John Aitken
2002 Nixon B, Jones RC, Hansen LA, Holland M, 'Rabbit epididymal secretory proteins. I. Characterization and hormonal regulation', Biology of Reproduction, 67 133-139 (2002) [C1]
Citations Scopus - 9Web of Science - 8
2002 Nixon B, Jones RC, Clarke H, Holland M, 'Rabbit epididymal secretory proteins. II. Immunolocalization and sperm association of REP38', Biology of Reproduction, 67 140-146 (2002) [C1]
Citations Web of Science - 3
2002 Nixon B, Hardy C, Jones RC, Anfrews J, Holland M, 'Rabbit epididymal secretory proteins. III. Molecular cloning and characterization of the complementary DNA for REP38', Biology of Reproduction, 67 147-153 (2002) [C1]
Citations Web of Science - 2
2001 Nixon B, Lu QX, Wassler MJ, Foote CI, Ensslin MA, Shur BD, 'Galactosyltransferase function during mammalian fertilization', CELLS TISSUES ORGANS, 168 46-57 (2001) [C1]
DOI 10.1159/000016805
Citations Web of Science - 57
1998 Holland MK, Nixon B, 'The specificity of epididymal secretory proteins', Journal of Reproduction and Fertility, 197-210 (1998)
1997 Hardy C, Clarke H, Nixon B, Hinds L, Holland M, 'Examination of the immunocontraceptive potential of recombinant fertilin subunits in rabbits', Biology of Reproduction, 57 879-886 (1997) [C1]
Citations Web of Science - 35
Show 65 more journal articles

Review (1 outputs)

Year Citation Altmetrics Link
2007 Nixon B, Aitken RJ, McLaughlin EA, 'New insights into the molecular mechanisms of sperm-egg interaction', CELLULAR AND MOLECULAR LIFE SCIENCES (2007) [D1]
DOI 10.1007/s00018-007-6552-x
Citations Scopus - 61Web of Science - 59
Co-authors Eileen Mclaughlin, John Aitken

Conference (58 outputs)

Year Citation Altmetrics Link
2012 Sobinoff AP, Beckett EL, Nixon B, Roman SD, Hansbro PM, McLaughlin EA, 'The impact of maternal cigarette smoke exposure on the male germline', Abstracts. The Annual Scientific Meeting of the Endocrine Society of Australia and the Society for Reproductive Biology 2012, Gold Coast, QLD (2012) [E3]
Co-authors Shaun Roman, Philip Hansbro, Eileen Mclaughlin
2012 Nixon BJ, Katen AL, Stanger SJ, Nixon B, Roman SD, 'Identifying biomarkers of chronic acrylamide exposure in the male germ line', Abstracts. The Annual Scientific Meeting of the Endocrine Society of Australia and the Society for Reproductive Biology 2012, Gold Coast, QLD (2012) [E3]
Co-authors Shaun Roman
2012 Nixon B, Redgrove KA, Baker MA, Aitken RJ, 'The role of molecular chaperones in regulating human sperm-egg recognition', Abstracts. The Annual Scientific Meeting of the Endocrine Society of Australia and the Society for Reproductive Biology 2012, Gold Coast, QLD (2012) [E3]
Co-authors Mark Baker, John Aitken
2012 Nixon B, 'Sperm maturation: Lessons from our distant relatives, the monotremes', Abstracts. The Annual Scientific Meeting of the Endocrine Society of Australia and the Society for Reproductive Biology 2012, Gold Coast, QLD (2012) [E3]
2012 Aitken RJ, Nixon B, Redgrove KA, Dun M, Baker MA, 'The molecular origins of defective sperm function', HUMAN REPRODUCTION, Istanbul, TURKEY (2012) [E3]
Co-authors Mark Baker, John Aitken, Matt Dun
2011 Dun MD, Aitken JR, Nixon B, 'The CCT/TRiC Complex Is Involved in Mediating Sperm-Oocyte Interaction', BIOLOGY OF REPRODUCTION, Portland, OR (2011) [E3]
Co-authors Matt Dun, John Aitken
2010 McIver SC, Roman SD, Nixon B, McLaughlin EA, 'MicroRNA signalling in early male germ cells', OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Vic (2010) [E3]
Co-authors Eileen Mclaughlin, Shaun Roman
2010 Nixon BJ, Nixon B, Roman SD, 'The effect of acrylamide exposure on early male germ cells', OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Vic (2010) [E3]
Co-authors Shaun Roman
2010 Pye VJ, Sobinoff AP, Nixon B, Roman SD, McLaughlin EA, 'Xenobiotics; influence on long term oocyte viability', OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Vic (2010) [E3]
Co-authors Shaun Roman, Eileen Mclaughlin
2010 Redgrove KA, McLaughlin EA, O'Bryan MK, Aitken RJ, Nixon B, 'Identification and characterisation of surface protein complexes in human spermatozoa', OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Vic (2010) [E3]
Co-authors John Aitken, Eileen Mclaughlin
2010 Reid AT, Roman SD, Aitken RJ, Nixon B, 'Investigation of the role of dynamin in sperm surface remodelling', OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Vic (2010) [E3]
Co-authors John Aitken, Shaun Roman
2010 Sobinoff AP, Pye VJ, Nixon B, Roman SD, McLaughlin EA, 'Consistent mechanism of primordial follicle activation in neonatal mouse ovotoxicity', OzBio 2010: The Molecules of Life - from Discovery to Biotechnology. Poster Abstracts, Melbourne, Vic (2010) [E3]
Co-authors Eileen Mclaughlin, Shaun Roman
2010 Redgrove KA, Nixon B, McLaughlin EA, O'Bryan MK, Aitken RJ, 'Identification and Characterisation of Surface Protein Complexes in Human Spermatozoa', Reproduction, Fertility and Development, Sydney (2010) [E3]
Co-authors Eileen Mclaughlin, John Aitken
2010 Sobinoff AP, Pye VJ, Nixon B, Roman SD, McLaughlin EA, 'Short Term Xenobiotic Exposure Compromises Long Term Oocyte Viability', Reproduction, Fertility and Development, Sydney (2010) [E3]
Co-authors Eileen Mclaughlin, Shaun Roman
2010 McIver SC, Roman SD, Nixon B, McLaughlin EA, 'Microrna and Early Male Germ Cells', Reproduction, Fertility and Development, Sydney (2010) [E3]
Co-authors Eileen Mclaughlin, Shaun Roman
2010 Dun MD, Aitken RJ, Nixon B, 'The Chaperonin Containing TCP-1 (CCT/TRIC) Multisubunit Complex is Involved in Mediating Sperm-Oocyte Interactions', Reproduction, Fertility and Development, Sydney (2010) [E3]
Co-authors Matt Dun, John Aitken
2010 Nixon BJ, Nixon B, Roman SD, 'The Consequences of Acrylamide Exposure on the Male Germline', Reproduction, Fertility and Development, Sydney (2010) [E3]
Co-authors Shaun Roman
2010 Anderson AL, Mitchell LA, McLaughlin EA, O'Bryan MK, Aitken RJ, Nixon B, 'Proteomic and Functional Analysis of Human Sperm Detergent Resistant Membranes', Reproduction, Fertility and Development, Sydney (2010) [E3]
DOI 10.1002/jcp.22615
Co-authors John Aitken, Eileen Mclaughlin
2010 Reid AT, Roman SD, Aitken RJ, Nixon B, 'Characterisation of the GTPASE dynamin throughout murine sperm maturation', Reproduction, Fertility and Development, Sydney, NSW (2010) [E3]
Co-authors John Aitken, Shaun Roman
2008 Nixon B, Bielanowicz AJ, McLaughlin EA, Tanphaichitr N, Ensslin M, Aitken RJ, 'The composition and significance of lipid rafts in mouse spermatozoa', Proceedings of 41st Annual Meeting of the Society for the Study of Reproduction., Kailua-Kona, Hawaii (2008) [E3]
Co-authors John Aitken, Eileen Mclaughlin
2008 Aitken RJ, De Iuliis GN, Nixon B, Roman SD, 'Causes and clinical significance of DNA damage in the male germ line', Proceedings of 41st Annual Meeting of the Society for the Study of Reproduction. "Reproductive Biology: Basic Discoveries that Affect Our Lives", Kailua-Kona, Hawaii (2008) [E3]
Co-authors Shaun Roman, Geoffry DeiuliIs, John Aitken
2008 Panayi GS, Asea A, Macario AJL, Triantafilou K, Nixon B, Csermely P, et al., 'Discussion', Novartis Foundation Symposium (2008) [E3]
Citations Scopus - 1
2008 Lund PA, Corrigall VM, Habich C, Panayi GS, Nixon B, Hightower LE, et al., 'Discussion', Novartis Foundation Symposium (2008) [E3]
2008 Henderson B, Lund PA, Feder ME, Gupta RS, Hightower LE, Macario AJL, et al., 'Discussion', Novartis Foundation Symposium (2008) [E2]
2008 Conway De Macario E, Ellis RJ, Csermely P, Lund PA, Cheetham M, Hightower LE, et al., 'Discussion', Novartis Foundation Symposium (2008) [E2]
2008 Ellis RJ, Henderson B, Lund PA, Coates ARM, Feder ME, Csermely P, et al., 'Discussion', Novartis Foundation Symposium (2008) [E2]
2008 Asea A, Csermely P, De Macario EC, Hightower LE, Nixon B, Calderwood SK, et al., 'Discussion', Novartis Foundation Symposium (2008) [E2]
2008 Ellis RJ, Pockley AG, Henderson B, Hightower LE, Panayi GS, Quintana FJ, et al., 'General discussion', Novartis Foundation Symposium (2008) [E3]
2008 Feder ME, Calderwood SK, De Macario EC, Asea A, Multhoff G, Cheetham M, et al., 'Discussion', Novartis Foundation Symposium (2008) [E2]
2008 Panayi GS, Gupta RS, Csermely P, Asea A, Multhoff G, Coates ARM, et al., 'Discussion', Novartis Foundation Symposium (2008) [E3]
2008 Feder ME, Ellis RJ, Calderwood SK, De Macario EC, Gupta RS, Lund PA, et al., 'Discussion', Novartis Foundation Symposium (2008) [E2]
2008 Aitken R, Do Iuliis G, Nixon B, Roman S, 'Causes and clinical significance of DNA damage in the male germ line', BIOLOGY OF REPRODUCTION, Kona, HI (2008) [E3]
Co-authors Shaun Roman, John Aitken
2008 Nixon B, Bielanowicz A, McLaughlin E, Tanphaichitr N, Ensslin M, Aitken R, 'The composition and significance of lipid rafts in mouse spermatozoa', BIOLOGY OF REPRODUCTION, Kona, HI (2008) [E3]
Co-authors Eileen Mclaughlin
2008 Mitchell L, Nixon B, Baker M, Aitken R, 'Investigation of the role of SRC in capacitation associated tyrosine phosphorylation of human spermatozoa', BIOLOGY OF REPRODUCTION, Kona, HI (2008) [E3]
Co-authors Mark Baker
2008 Mitchell LA, Nixon B, Aitken RJ, 'Investigation of the role of lipid rafts in human sperm-zona pellucida binding', Biology of Reproduction, Kailua-Kona, Hawaii (2008) [E3]
Co-authors John Aitken
2007 Schjenken JE, Stanger SJ, Smith V, Douglas A, De Iuliis GN, Depaz I, et al., 'Expression and activity of phase 1 detoxifying enzymes in the male sperm line of the mouse', 7th Hunter Cellular Biology Meeting. Program, Hunter Valley, NSW (2007) [E3]
Co-authors John Aitken, Shaun Roman, Geoffry DeiuliIs
2007 Jones RC, Dacheaux J-L, Nixon B, Ecroyd HW, 'The role of epididymis in sperm competition', Australian Mammal Society 53rd Scientific Meeting. Programme and Abstracts, Armidale, NSW (2007) [E3]
2006 Nixon B, Walsh A, Harman A, Aitken RJ, 'The role of molecular chaperones in sperm-oocyte interaction', JOURNAL OF ANDROLOGY, Chicago, IL (2006)
Co-authors John Aitken
2006 Aitken RJ, Baker MA, Lee YH, Lin M, Nixon B, 'Proteomic Changes in Mouse Spermatozoa During Epididymal Transit', Abstracts, Chatel-Guyon, Auvergne, France (2006) [E3]
Co-authors Minjie Lin, John Aitken, Mark Baker
2006 Mitchell LA, Nixon B, Macintyre DA, Gibbs GM, O'Bryan M, Aitken RJ, 'The Role of Decapacitation Factors in the Regulation of Mouse Sperm Capacitation', Book of Abstracts, Lorne, Victoria, Australia (2006) [E3]
Co-authors John Aitken
2006 Nixon B, Paul JW, Spiller CM, Attwell-Heap AG, Aitken RJ, 'Evidence for the Involvement of Pecam-1 in a Reception Mediated Signal-Transduction Pathway regulating Capacitation-Associated Tyrosine Phosphorylation in Human Spermatozoa', Book of Abstracts, Lorne, Victoria, Australia (2006) [E3]
Co-authors Jonathan Paul, John Aitken
2006 Walsh AK, Bielanowicz AJ, Mitchell LA, Spiller CM, Nixon B, Aitken RJ, 'Identification of a Metalloprotease, Adamts10, in Complex with Sperm Surface Molecular Chaperones', Book of Abstracts, Lorne, Victoria, Australia (2006) [E3]
Co-authors John Aitken
2006 Nixon B, Walsh AK, Bielanowicz AJ, Aitken RJ, 'The role of molecular chaperones in sperm-oocyte interaction', Book of Abstracts, Chicago, Illinois (2006) [E3]
Co-authors John Aitken
2005 Aitken RJ, Bennets L, Wingate J, Koppers A, Gallagher S, Roman S, et al., 'Estrogenic steroids and quinines as mediators of DNA damage in the male germ line', Couran Cove (2005) [E3]
2005 Ainsworth C, Nixon B, Aitken RJ, 'Profiling of sperm populations fractionated using novel microflow electrophoretic device', Adelaide, Australia (2005) [E3]
2005 Dacheux J-L, Belghazi M, Dacheux F, Nixon B, Jones RC, 'The epididymis secretes proteins involved in sperm competition: Evidence from the echidna', Perth, Australia (2005) [E3]
2004 Nixon B, Bielanowicz AJ, Asquith KL, Aitken RJ, 'The Molecular Basis of Epididymal Sperm Maturation', Reproduction, Fertility and Development, Sydney (2004) [E3]
Co-authors John Aitken
2004 Walsh AK, Asquith KL, Thomas CM, Mitchell LA, Nixon B, Aitken RJ, 'Identification of Potential Zona Pellucida-binding Sperm Proteins using Heat Shock Protein 60', Reproduction, Fertility and Development, Sydney (2004) [E3]
Co-authors John Aitken
2004 Asquith KL, Nixon B, McLaughlin EA, Aitken RJ, 'Tyrosine phosphorylation of mouse sperm proteins in a prerequisite for Zona Pellucida binding: potential involvement of molecular chaperones', Biology of Reproduction 2004 Special Issue, Vancouver, Canada (2004) [E3]
Co-authors Eileen Mclaughlin, John Aitken
2003 Asquith KL, Nixon B, Aitken RJ, 'Surface Localisation of Chaperone Proteins in Spermatozoa', 28th Annual Lorne Conference on Protein Structure & Function, Lorne, Victoria (2003) [E3]
Co-authors John Aitken
2003 Nixon B, Paul JW, Aitken RJ, 'Wheat germ agglutinin induced tyrosine phosphorylation of human spermatozoa', 28th Annual Lorne Conference on Protein Structure & Function, Lorne, Victoria (2003) [E3]
Co-authors John Aitken, Jonathan Paul
2003 Nixon B, Attwell-Heap AG, Paul JW, Aitken RJ, 'Wheat Germ Agglutinin Induced Tyrosine Phosphorylation of Human Spermatozoa', Reproduction, Fertility and Development, Melbourne (2003) [E3]
Co-authors Jonathan Paul, John Aitken
2003 Asquith KL, McLaughlin EA, Nixon B, Aitken RJ, 'Localisation of Tyrosine Phosphorylated Proteins on Mouse Spermatozoa during Zona Pellucida Interaction and Characterisation of Sperm Surface Phosphoproteins', Society for Reproductive Biology Proceedings of the Thirty-fourth Annual Conference, Melbourne (2003) [E3]
Co-authors Eileen Mclaughlin, John Aitken
2003 Nixon B, Clulow J, Ewen K, Krivanek K, Dacheux J-L, Jones RC, 'The avian epididymis: a model to study epididymal function?', Melbourne (2003) [E3]
2003 Jones RC, Clulow J, Kidd GJ, Chaturapanich G, Nixon B, Dacheux J, 'The Avian Epididymis: A Simple Conduit or a Sophisticated Adaptation?', The Third International Conference on the Epididymis, Charlottesville, Virginia (2003) [E2]
Co-authors John Clulow
2003 Nixon B, Jones RC, Holland MK, 'Characterization of REP52, a rabbit epididymal secretory protein that interacts with the sperm tail', The Third International Conference on the Epididymis, Charlottesville, Virginia (2003) [E3]
1998 Holland MK, Nixon B, 'The specificity of epididymal secretory proteins', JOURNAL OF REPRODUCTION AND FERTILITY, ROBERTSON, AUSTRALIA (1998)
Citations Scopus - 21
1998 Hollland MK, Nixon B, 'The specificity of epididymal secretory proteins', The Epididymis: Cellular and Molecular Aspects, Robertson, NSW Australia (1998) [E1]
Show 55 more conferences
Edit

Grants and Funding

Summary

Number of grants 45
Total funding $6,331,095

Click on a grant title below to expand the full details for that specific grant.


20151 grants / $403,300

Use of quinone adducted peptides in the regulation of fertility$403,300

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Laureate Professor John Aitken, Associate Professor Brett Nixon
Scheme Discovery Projects
Role Investigator
Funding Start 2015
Funding Finish 2015
GNo G1400318
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

20148 grants / $1,459,353

Investigation of novel mechanisms for the regulation of sperm-oocyte interactions$882,232

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Associate Professor Brett Nixon
Scheme Future Fellowships
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1301259
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

miRNA regulation of sperm maturation $383,447

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Associate Professor Brett Nixon, Professor Eileen McLaughlin, Doctor Janet Holt
Scheme Project Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1300125
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

JuLI Stage $71,674

Funding body: NHMRC (National Health & Medical Research Council)

DVC(R) Research Support for Future Fellow (FT14)$60,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Brett Nixon
Scheme Special Project Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1400948
Type Of Funding Internal
Category INTE
UON Y

The Role of the GTPase Dynamin in the Female Germline$30,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Ms Kate Redgrove, Doctor Janet Holt, Professor Eileen McLaughlin, Associate Professor Brett Nixon
Scheme Bridging Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1301333
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

The role of dynamin is spermatogenesis and sperm-oocyte interactions$20,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Brett Nixon, Professor Eileen McLaughlin, Professor Adam McCluskey
Scheme Near Miss Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1301400
Type Of Funding Internal
Category INTE
UON Y

Development of contraception on demand $10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Brett Nixon, Laureate Professor John Aitken
Scheme Near Miss Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1301399
Type Of Funding Internal
Category INTE
UON Y

Faculty PVC Conference Assistance Grant 2014$2,000

Funding body: University of Newcastle - Faculty of Science & IT

Funding body University of Newcastle - Faculty of Science & IT
Project Team Associate Professor Brett Nixon
Scheme PVC Conference Assistance Grant
Role Lead
Funding Start 2014
Funding Finish 2014
GNo G1401230
Type Of Funding Internal
Category INTE
UON Y

20136 grants / $381,182

Novel function of heat shock protein 2A in the regulation of human sperm-egg interactions$292,182

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Associate Professor Brett Nixon, Laureate Professor John Aitken, Professor Eileen McLaughlin
Scheme Project Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1200193
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Novel mechanisms for the regulation of sperm-oocyte interactions$20,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Brett Nixon
Scheme Near Miss Grant
Role Lead
Funding Start 2013
Funding Finish 2013
GNo G1300458
Type Of Funding Internal
Category INTE
UON Y

NucleoCounter SP100$14,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Laureate Professor John Aitken, Associate Professor Brett Nixon, Doctor Shaun Roman, Doctor Mark Baker, Doctor Geoffry De Iuliis, Doctor Lisa Mitchell, Doctor Matthew Jobling, Doctor Zamira Gibb, Mr Nenad Naumovski
Scheme Equipment Grant
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1201175
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Dynamin - role in sperm oocyte interaction$10,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Eileen McLaughlin, Associate Professor Brett Nixon, Professor Adam McCluskey
Scheme Near Miss Grant
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1300483
Type Of Funding Internal
Category INTE
UON Y

Dynamin - role in sperm oocyte interaction$10,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Eileen McLaughlin, Associate Professor Brett Nixon, Professor Adam McCluskey
Scheme Near Miss
Role Investigator
Funding Start 2013
Funding Finish 2013
GNo G1300700
Type Of Funding External
Category EXTE
UON Y

20122 grants / $17,447

The role of miRNAs in the regulation of sperm maturation$10,000

Funding body: University of Newcastle - Faculty of Science & IT

Funding body University of Newcastle - Faculty of Science & IT
Project Team Associate Professor Brett Nixon, Professor Eileen McLaughlin, Doctor Natalie Beveridge
Scheme Strategic Initiative Research Fund (SIRF)
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1401028
Type Of Funding Internal
Category INTE
UON Y

Faculty Visiting Fellowship 2012$7,447

Funding body: University of Newcastle - Faculty of Science & IT

Funding body University of Newcastle - Faculty of Science & IT
Project Team Associate Professor Brett Nixon
Scheme Visiting Fellowship
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1401130
Type Of Funding Internal
Category INTE
UON Y

20112 grants / $40,000

SLX4 - a key regulator of male germ cell development and DNA repair$25,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Professor Eileen McLaughlin, Associate Professor Brett Nixon
Scheme Project Grant
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1001000
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Eppendorf mastercycler pro with thermomixer comfort and 5430R centrifuge$15,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Eileen McLaughlin, Professor Peter Lewis, Professor Adam McCluskey, Conjoint Professor Keith Jones, Associate Professor Brett Nixon, Doctor Shaun Roman, Doctor Jennette Sakoff, Doctor Ian Grainge, Doctor Janet Holt, Doctor Xiao Yang
Scheme Equipment Grant
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1100028
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20106 grants / $1,645,000

An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$500,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Adam McCluskey, Laureate Professor John Aitken, Professor Paul Dastoor, Professor Phillip Robinson, Professor Eileen McLaughlin, Emeritus Professor Geoffrey Lawrance, Professor Marcel Maeder, Professor Hugh Dunstan, Doctor Shaun Roman, Professor Rob Atkin, Doctor Clovia Holdsworth, Doctor Mark Baker, Doctor Nikki Verrills, Professor Gottfried Otting, Associate Professor Brett Nixon, Doctor Xiaojing Zhou, Ms Megan Chircop, Doctor Warwick Belcher
Scheme Linkage Infrastructure Equipment & Facilities (LIEF)
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo G0190402
Type Of Funding Scheme excluded from IGS
Category EXCL
UON Y

Laser microdissection microscopy system for cell and development biology$350,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Professor Eileen McLaughlin, Conjoint Professor Keith Jones, Laureate Professor John Aitken, Associate Professor Brett Nixon, Doctor Shaun Roman, Professor Alan Brichta, Doctor Rick Thorne, Doctor Doug Smith, Associate Professor David McCurdy, Conjoint Professor Ray Rose, Professor Christopher Grof, Emeritus Professor Leonie Ashman, Professor Gordon Burns, Doctor Brett Graham, Associate Professor Paul Tooney, Professor Roger Smith, Laureate Professor Paul Foster, Professor Trevor Day, Professor Robert Callister
Scheme Linkage Infrastructure Equipment & Facilities (LIEF)
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo G0190369
Type Of Funding Scheme excluded from IGS
Category EXCL
UON Y

An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$280,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Adam McCluskey, Laureate Professor John Aitken, Professor Paul Dastoor, Professor Phillip Robinson, Professor Eileen McLaughlin, Emeritus Professor Geoffrey Lawrance, Professor Marcel Maeder, Professor Hugh Dunstan, Doctor Shaun Roman, Professor Rob Atkin, Doctor Clovia Holdsworth, Doctor Mark Baker, Doctor Nikki Verrills, Professor Gottfried Otting, Associate Professor Brett Nixon, Doctor Xiaojing Zhou, Ms Megan Chircop, Doctor Warwick Belcher
Scheme Equipment Grant
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo G1000873
Type Of Funding Internal
Category INTE
UON Y

Monotremes provide a key to understanding the molecular biology of mammalian gamete evolution$270,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Associate Professor Brett Nixon, Dr Heath Ecroyd, Conjoint Associate Professor Russell Jones
Scheme Discovery Projects
Role Lead
Funding Start 2010
Funding Finish 2010
GNo G0190056
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Waters, Ultra high performance liquid chromatography system (nano-Aquity) $30,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Mark Baker, Laureate Professor John Aitken, Professor Adam McCluskey, Associate Professor Brett Nixon, Emeritus Professor John Rostas, Professor Eileen McLaughlin
Scheme Equipment Grant
Role Investigator
Funding Start 2010
Funding Finish 2010
GNo G1000051
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20095 grants / $1,319,000

Characterization of the molecular basis of human sperm-oocyte interaction$474,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Associate Professor Brett Nixon, Professor Eileen McLaughlin, Dr M O'Bryan
Scheme Project Grant
Role Lead
Funding Start 2009
Funding Finish 2009
GNo G0188867
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Confocal Laser Scanning Microscopy for Live Cell Imaging$275,000

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Conjoint Professor Keith Jones, Professor Eileen McLaughlin, Laureate Professor John Aitken, Conjoint Professor Ray Rose, Emeritus Professor John Patrick, Conjoint Professor Christina Offler, Associate Professor David McCurdy, Emeritus Professor Leonie Ashman, Professor Gordon Burns, Professor Dirk Van Helden, Doctor Nikki Verrills, Associate Professor Brett Nixon, Doctor Shaun Roman, Associate Professor Yong-Ling Ruan, Doctor Rick Thorne, Professor Mike Calford
Scheme Linkage Infrastructure Equipment & Facilities (LIEF)
Role Investigator
Funding Start 2009
Funding Finish 2009
GNo G0189038
Type Of Funding Scheme excluded from IGS
Category EXCL
UON Y

LAS-4000 Chemiluminescence imaging system$25,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Eileen McLaughlin, Laureate Professor John Aitken, Professor Peter Lewis, Associate Professor Brett Nixon, Doctor Shaun Roman
Scheme Equipment Grant
Role Investigator
Funding Start 2009
Funding Finish 2009
GNo G0189852
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20084 grants / $405,060

Xenobiotics - ocidative stress in the mammalian ovary$362,625

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Professor Eileen McLaughlin, Associate Professor Brett Nixon, Doctor Shaun Roman
Scheme Project Grant
Role Investigator
Funding Start 2008
Funding Finish 2008
GNo G0187620
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Understanding the aetiology of human male infertility: Elucidation of the mechanisms underpinning sperm-egg interaction$21,650

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Brett Nixon, Professor Eileen McLaughlin
Scheme Project Grant
Role Lead
Funding Start 2008
Funding Finish 2008
GNo G0188465
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

Characterization of the molecular basis of mouse sperm-oocyte interaction$18,285

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Brett Nixon, Professor Eileen McLaughlin
Scheme Near Miss Grant
Role Lead
Funding Start 2008
Funding Finish 2008
GNo G0188405
Type Of Funding Internal
Category INTE
UON Y

41st Annual Meeting of the Society for the Study of Reproduction $2,500

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Brett Nixon
Scheme Travel Grant
Role Lead
Funding Start 2008
Funding Finish 2008
GNo G0188643
Type Of Funding Internal
Category INTE
UON Y

20074 grants / $51,471

Chemokines and spermatogenesis: roles of SDF-1 and CXCR-4 in the establishment of spermatogenesis$20,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Professor Eileen McLaughlin, Doctor Shaun Roman, Associate Professor Brett Nixon
Scheme Near Miss Grant
Role Investigator
Funding Start 2007
Funding Finish 2007
GNo G0187197
Type Of Funding Internal
Category INTE
UON Y

Determination of the molecular processes involved in post-testicular development of sperm in the platypus and their relationship with sperm competition$16,471

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Brett Nixon, Conjoint Associate Professor Russell Jones
Scheme Near Miss Grant
Role Lead
Funding Start 2007
Funding Finish 2007
GNo G0187188
Type Of Funding Internal
Category INTE
UON Y

Validation of novel model to explain the functional activation of mouse spermatozoa$7,998

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Brett Nixon
Scheme Pilot Grant
Role Lead
Funding Start 2007
Funding Finish 2007
GNo G0187878
Type Of Funding Internal
Category INTE
UON Y

Validation of novel model to explain the functional activation of mouse spermatozoa$7,002

Funding body: University of Newcastle - Faculty of Science & IT

Funding body University of Newcastle - Faculty of Science & IT
Project Team Associate Professor Brett Nixon
Scheme Pilot Grant
Role Lead
Funding Start 2007
Funding Finish 2007
GNo G0188360
Type Of Funding Internal
Category INTE
UON Y

20061 grants / $544,282

PRC - Priority Research Centre for Reproductive Science$544,282

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Laureate Professor John Aitken, Professor Roger Smith, Professor Eileen McLaughlin, Associate Professor Brett Nixon, Doctor Shaun Roman, Conjoint Associate Professor Vicki Clifton, Conjoint Professor Warwick Giles, Professor Jon Hirst, Conjoint Associate Professor Rick Nicholson, Professor Ian Symonds
Scheme Priority Research Centre
Role Investigator
Funding Start 2006
Funding Finish 2006
GNo G0186945
Type Of Funding Internal
Category INTE
UON Y

20051 grants / $9,000

The initiation of fertilisation: Characterisation of the sperm receptor complex for the oocyte$9,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Brett Nixon, Laureate Professor John Aitken
Scheme Project Grant
Role Lead
Funding Start 2005
Funding Finish 2005
GNo G0184742
Type Of Funding Internal
Category INTE
UON Y

20043 grants / $29,000

Characterisation of a novel recepto-mediated signal transduction pathway in human spermatozoa.$14,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Brett Nixon, Emeritus Professor Leonie Ashman
Scheme Project Grant
Role Lead
Funding Start 2004
Funding Finish 2004
GNo G0183444
Type Of Funding Internal
Category INTE
UON Y

Molecular basis of sperm-egg interaction: Identification of the receptor complex for ZP3$8,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Brett Nixon, Doctor Benjamin Curry
Scheme Project Grant
Role Lead
Funding Start 2004
Funding Finish 2004
GNo G0183415
Type Of Funding Internal
Category INTE
UON Y

The role of the father in recurrent early pregnancy loss$7,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Brett Nixon
Scheme Adamstown Lions Club
Role Lead
Funding Start 2004
Funding Finish 2004
GNo G0183756
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

20021 grants / $12,000

The role of protein tyrosine phosphorylation in mouse sperm-oocyte interaction$12,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Brett Nixon
Scheme Early Career Researcher Grant
Role Lead
Funding Start 2002
Funding Finish 2002
GNo G0182255
Type Of Funding Internal
Category INTE
UON Y

20011 grants / $15,000

The role of protein tyrosine phosphorylation in mouse sperm-oocyte interaction$15,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Associate Professor Brett Nixon
Scheme Early Career Researcher Grant
Role Lead
Funding Start 2001
Funding Finish 2001
GNo G0180831
Type Of Funding Internal
Category INTE
UON Y
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Research Supervision

Number of supervisions

Completed11
Current12

Total current UON EFTSL

Masters0.2
PhD4.16

Current Supervision

Commenced Level of Study Research Title / Program / Supervisor Type
2015 Masters Repair of DNA Damage in Spermatozoa by the Early Embryo
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2015 PhD miRNAs in Sperm Maturation
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2015 PhD Investigating New Contraceptives; Immunocontraception
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2015 PhD The Role of miRNAs in the Regulation of Sperm Maturation
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2014 PhD Radiofrequency Electromagnetic Radiation and the Male Reproduction
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2014 PhD Identification of Novel Immunocontraceptive Targets for Fertility Control of Feral Horses
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2014 PhD An Investigation of Equine Oocyte Maturation to Improve IVF and Embryo Retention Rates
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2013 PhD Genetic Consequences of Paternal Acrylamide Exposure and Potential for Amelioration
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2013 PhD Phage Peptides Fertility Control
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2013 PhD Post-Meiotic Sperm DNA Damage and Consequences to Offspring
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2012 PhD The Function of Molecular Chaperones in Human Sperm-Egg Recognition
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2012 PhD The Role of Reactive Oxygen Species and Oxidative Stress in Post-Ovulatory Ageing and Apoptosis of the Mammalian Oocyte
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor

Past Supervision

Year Level of Study Research Title / Program / Supervisor Type
2015 PhD Functional Characterisation of Dynamin in Mouse Spermatozoa
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2014 PhD The Consequences of Acrylamide Exposure of the Male Germ Line
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2013 PhD Regulation of the Transition from Gonocytes to Spermatogonia
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2013 PhD New Insights into the Molecular Basis of Human Sperm-Egg Interaction
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2012 PhD The Molecular Basis of Sperm - Oocyte Interactions
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Principal Supervisor
2012 PhD Xenobiotics; Effects on Female Fertility
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2010 PhD Significance of Mitochondrial Reactive Oxygen Species Production in Male Infertility
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2009 PhD The Molecular Basis of Human Sperm-Zona Pellucida Interaction
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2007 Masters Identification of NADPH Oxidase in Mouse Spermatozoa
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2007 PhD The Development of a Novel Electrophoretic System for the Isolation of Human Spermatozoa
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2005 PhD The Molecular Basis of Sperm-Oocyte Interaction in the Mouse
Biological Sciences, Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
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News

Australian Research Council (ARC)

ARC Discovery Project funding success

November 19, 2014

Laureate Professor John Aitken and Associate Professor Brett Nixon have been awarded more than $403,000 in ARC Discovery Project funding commencing in 2015 for their research project Use of quinone adducted peptides in the regulation of fertility.

ARC Future Fellows

July 23, 2014

Six mid-career researchers at the University of Newcastle (UON) have received funding under the Australian Research Council's (ARC) Future Fellowships scheme, just announced.

Associate Professor Brett Nixon

Position

ARC Future Fellow
School of Environmental and Life Sciences
Faculty of Science and Information Technology

Focus area

Biological Sciences

Contact Details

Email brett.nixon@newcastle.edu.au
Phone (02) 4921 6977
Fax (02) 4921 6923

Office

Room LS4-40
Building Life Sciences
Location Callaghan
University Drive
Callaghan, NSW 2308
Australia
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