Dr Jude Weidenhofer

Lecturer

School of Biomedical Sciences and Pharmacy (Medical Biochemistry)

Career Summary

Biography

I completed my PhD investigating the molecular and cellular role of the amygdala in the aetiology of schizophrenia in 2006 at the University of Newcastle. Following a post-doctoral position at the Children's Oncology Unit at the Children's Hospital at Westmead investigating the role of TPD52 in breast development and breast cancer I returned to the University of Newcastle in 2008. Whilst this position was as a teaching focused academic, I initiated my own research direction under the supervision of Prof. Leonie Ashman which resulted in successful funding from the Prostate Cancer Foundation of Australia. Since 2011 I have lead my own research group investigating the regulation of the expression of tetraspanin proteins in breast and prostate cancers as well as the role of CD151 in glomerular disease.

Research Expertise
My current research focus is on understanding the role of three tetraspanin proteins, CD151, CD9 and CD82 in breast and prostate cancers. These proteins show de-regulated expression in these cancers which is consistent with their proposed roles as tumour and metastasis enhancers (CD151) or suppressors (CD9 & CD82). Our aim is to identify the molecular mechanisms underlying their altered expression in cancer with a current focus on the role of miRNA and the ubiquitin system. We hope that by improving our understanding of how the expression of these proteins is controlled we can gain valuable insight into how they can be used as both prognostic indicators as well as novel therapeutic targets, particularly for metastatic disease. In addition we are investigating the role that CD151 plays in the development and maintenance of the glomerular filtration barrier in the kidney. In particular we aim to identify biomarkers of glomerular disease through analyzing mice in which CD151 expression has been lost and identifying the mechanisms involved in the development of and susceptibility to disease.

Teaching Expertise
My current teaching focus is on genetics, bioinformatics and cancer cell biology. I also have experience in DNA, transcription, translation, protein synthesis and function, protein analysis and molecular biology. I have experience teaching B.Biomed Sci, M. Pharmacy and B. Medicine.

Administrative Expertise
I have been on the organising committee for several symposiums and research seminar series as well as other research related events. I am currently the NSW State representative for the Australian Society for Biochemistry and Molecular Biology (ASBMB). In a teaching capacity I have co-ordinated several courses at the University of Newcastle.


Qualifications

  • Doctor of Philosophy, University of Newcastle

Keywords

  • Bioinformatics
  • Breast Cancer
  • Cancer Cell Biology
  • Gene & Protein expression regulation
  • Genetics
  • Molecular Biology
  • Prostate Cancer
  • Protein biochemistry
  • Tetraspanin proteins

Fields of Research

Code Description Percentage
060405 Gene Expression (incl. Microarray and other genome-wide approaches) 25
060802 Animal Cell and Molecular Biology 25
111299 Oncology and Carcinogenesis not elsewhere classified 50

Professional Experience

UON Appointment

Title Organisation / Department
Lecturer University of Newcastle
School of Biomedical Sciences and Pharmacy
Australia

Academic appointment

Dates Title Organisation / Department
1/07/2006 - 1/05/2008 Post-doctoral Researcher The Children's Hospital at Westmead
Molecular Oncogoly Group
Australia
1/01/2006 -  Membership - Australian Society of Medical Research Australian Society of Medical Research
Australia
1/01/2006 -  Membership - Australian Society of Biochemistry and Molecular Biology Australian Society of Biochemistry and Molecular Biology
Australia

Professional appointment

Dates Title Organisation / Department
1/03/2012 -  NSW State Representative Australian Society of Biochemistry and Molecular Biology
Australia

Invitations

Speaker

Year Title / Rationale
2012 Role and regulation of tetraspanins CD151 and CD9 in breast and prostate cancers
Organisation: Institut Andre Lwoff
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (1 outputs)

Year Citation Altmetrics Link
2009 Weidenhofer J, Byrne JA, 'Isolation of nucleic acids from hard tissues', Handbook of Nucleic Acid Purification, CRC PressI Llc, United States 427-448 (2009)

Journal article (14 outputs)

Year Citation Altmetrics Link
2014 Vuong QV, Sadeqzadeh E, Hirun S, Goldsmith CD, Zammitt N, Bowyer MB, et al., 'Phenolic Compounds, Antioxidant and Anti-Cancer Properties of the Australian Maroon Bush Scaevola spinescens (Goodeniaceae)', Journal of Bioanalysis & Biomedicine, S12 (2014) [C1]
DOI 10.4172/1948-593X.S12-002
Co-authors Vanquan Vuong, C Scarlett, Jennette Sakoff, Michael Bowyer, Rick Thorne
2014 Roselli S, Kahl RGS, Copeland BT, Naylor MJ, Weidenhofer J, Muller WJ, Ashman LK, 'Deletion of Cd151 reduces mammary tumorigenesis in the MMTV/PyMT mouse model', BMC Cancer, 14 (2014) [C1]

Background: Tetraspanins are transmembrane proteins that serve as scaffolds for multiprotein complexes containing, for example, integrins, growth factor receptors and matrix metal... [more]

Background: Tetraspanins are transmembrane proteins that serve as scaffolds for multiprotein complexes containing, for example, integrins, growth factor receptors and matrix metalloproteases, and modify their functions in cell adhesion, migration and transmembrane signaling. CD151 is part of the tetraspanin family and it forms tight complexes with ß1 and ß4 integrins, both of which have been shown to be required for tumorigenesis and/or metastasis in transgenic mouse models of breast cancer. High levels of the tetraspanin CD151 have been linked to poor patient outcome in several human cancers including breast cancer. In addition, CD151 has been implicated as a promoter of tumor angiogenesis and metastasis in various model systems.Methods: Here we investigated the effect of Cd151 deletion on mammary tumorigenesis by crossing Cd151-deficient mice with a spontaneously metastasising transgenic model of breast cancer induced by the polyoma middle T antigen (PyMT) driven by the murine mammary tumor virus promoter (MMTV).Results: Cd151 deletion did not affect the normal development and differentiation of the mammary gland. While there was a trend towards delayed tumor onset in Cd151 -/- PyMT mice compared to Cd151 +/+ PyMT littermate controls, this result was only approaching significance (Log-rank test P-value =0.0536). Interestingly, Cd151 deletion resulted in significantly reduced numbers and size of primary tumors but did not appear to affect the number or size of metastases in the MMTV/PyMT mice. Intriguingly, no differences in the expression of markers of cell proliferation, apoptosis and blood vessel density was observed in the primary tumors.Conclusion: The findings from this study provide additional evidence that CD151 acts to enhance tumor formation initiated by a range of oncogenes and strongly support its relevance as a potential therapeutic target to delay breast cancer progression. © 2014 Roselli et al.; licensee BioMed Central Ltd.

DOI 10.1186/1471-2407-14-509
Citations Scopus - 5Web of Science - 1
Co-authors Leonie Ashman
2014 Bond DB, Brzozowski J, Skelding KA, Roselli SR, Weidenhofer J, 'Use of tetraspanins CD151 and CD9 as biomarkers for breast cancer', Breast Cancer Management, 3 123-126 (2014) [C3]
DOI 10.2217/bmt.14.2
Co-authors Kathryn Skelding
2014 Mate K, Riveros C, Weidenhofer J, Goldie B, Scott J, Moscato P, et al., 'Strategies for Enhancing Communication between Students, Academics and Researchers participating in Large-Scale Undergraduate Research Projects', International Journal of Innovation in Science and Mathematics Education, 22 14-29 (2014) [C1]
Co-authors Carlos Riveros, Karen Mate, Liz Milward, Pablo Moscato
2013 Mate K, Sim A, Weidenhofer J, Milward L, Scott J, 'Investigation of the human disease osteogenesis imperfecta: A research-based introduction to concepts and skills in biomolecular analysis', Biochemistry & Molecular Biology Education, 41 103-109 (2013) [C1]
DOI 10.1002/bmb.20672
Citations Scopus - 1
Co-authors Karen Mate, Liz Milward, Alistair Sim
2012 Tynan R, Weidenhofer JC, Hinwood M, Cairns MJ, Day TA, Walker FR, 'A comparative examination of the anti-inflammatory effects of SSRI and SNRI antidepressants on LPS stimulated microglia', Brain Behavior and Immunity, 26 469-479 (2012) [C1]
Citations Scopus - 80Web of Science - 56
Co-authors Madeleine Hinwood, Murray Cairns, Rohan Walker
2009 Weidenhofer JC, Ashman LK, 'CD151 (CD151 molecule (Raph blood group))', Atlas of Genetics and Cytogenetics in Oncology and Haematology, - - (2009) [C1]
Co-authors Leonie Ashman
2009 Weidenhofer JC, Scott R, Tooney PA, 'Investigation of the expression of genes affecting cytomatrix active zone function in the amygdala in schizophrenia: Effects of antipsychotic drugs', Journal of Psychiatric Research, 43 282-290 (2009) [C1]
DOI 10.1016/j.jpsychires.2008.04.001
Citations Scopus - 8Web of Science - 8
Co-authors Paul Tooney, Rodney Scott
2008 Shehata M, Bieche I, Boutros R, Weidenhofer J, Fanayan S, Spalding L, et al., 'Nonredundant Functions for Tumor Protein D52-Like Proteins Support Specific Targeting of TPD52', Clinical Cancer Research, 14 5050-5060 (2008) [C1]
DOI 10.1158/1078-0432.CCR-07-4994
Citations Scopus - 23Web of Science - 18
2008 Shehata M, Weidenhofer J, Thamotharampillai K, Byrne JA, 'Tumor protein D52 overexpression and gene amplification in cancer - from a mosaic of microarrays', Critical Reviews in Oncogenesis, 14 33-55 (2008) [C1]
Citations Scopus - 12
2006 Weidenhofer JC, Bowden NA, Scott R, Tooney PA, 'Altered gene expression in the amygdala in schizophrenia: Up-regulation of genes located in the cytomatrix active zone', Molecular and Cellular Neuroscience, 31 243-250 (2006) [C1]
DOI 10.1016/j.mcn.2005.09.013
Citations Scopus - 36Web of Science - 36
Co-authors Rodney Scott, Nikola Bowden, Paul Tooney
2006 Weidenhofer JC, Yip JR, Zavitsanou K, Huang XF, Chahl LA, Tooney PA, 'Immunohistochemical localisation of the NK1 receptor in the human amygdala: Preliminary investigation in schizophrenia', Progress in Neuro-Psychopharmacology and Biological Psychiatry, 30 1313-1321 (2006) [C1]
DOI 10.1016/j.pnpbp.2006.05.008
Citations Scopus - 6Web of Science - 5
Co-authors Paul Tooney
2006 Bowden NA, Weidenhofer JC, Scott R, Schall U, Todd J, Michie PT, Tooney PA, 'Preliminary investigation of gene expression profiles in peripheral blood lymphocytes in schizophrenia', Schizophrenia Research, 82 175-183 (2006) [C1]
DOI 10.1016/j.schres.2005.11.012
Citations Scopus - 81Web of Science - 68
Co-authors Nikola Bowden, Ulrich Schall, Rodney Scott, Juanita Todd, Pat Michie, Paul Tooney
2006 Weidenhofer J, Bowden NA, Scott RJ, Tooney PA, 'Dysfunction of genes regulating membrane exocytosis in schizophrenia', AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, 40 A129-A129 (2006)
Co-authors Paul Tooney, Rodney Scott, Nikola Bowden
Show 11 more journal articles

Conference (19 outputs)

Year Citation Altmetrics Link
2015 Jankowski H, Goldie B, Brzozowski J, Bond D, Scarlett C, Skelding KA, Weidenhofer J, 'Differences in extracellular vesicle nucleic acid content show promise as prostate cancer biomarkers' (2015) [O1]
Co-authors Kathryn Skelding, C Scarlett
2015 Naudin C, Weidenhofer J, Roselli S, Keely S, 'Induction of Mindin is Associated with Pathological Changes in the Kidney of Cd151(-/-) Mice', FASEB JOURNAL (2015) [E3]
Co-authors Simon Keely
2015 Brzozowski J, Coldie B, Jankowski H, Bond D, Scarlett C, Dun M, et al., 'THE EFFECTS OF ALTERED CD9 AND CD151 EXPRESSION ON PROSTATE EXOSOMES', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2015) [E3]
Co-authors C Scarlett, Matt Dun, Kathryn Skelding
2015 Jankowski H, Goldie B, Brzozowski J, Bond D, Scarlett C, Skelding K, Weidenhofer J, 'PROSTATE CANCER BIOMARKERS: ARE EXTRACELLULAR VESICLES THE SOLUTION?', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2015) [E3]
Co-authors Kathryn Skelding, C Scarlett
2015 Bond D, Turner A, Richmond R, Sadeqzadeh E, Vuong Q, Bhuyan D, et al., 'THE SEARCH FOR NOVEL TREATMENT AGENTS FOR PANCREATIC CANCER: TALES FROM THE LAND AND SEA', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2015) [E3]
Co-authors Michael Bowyer, Anita Chalmers, Jennette Sakoff, Troy Gaston, Vanquan Vuong, C Scarlett
2015 Predebon M, Bond D, Brzozowski J, Jankowski H, Deane F, Tarleton M, et al., 'A BISPIDINONE ANALOGUE INDUCES AN APOPTOSIS-MEDIATED CYTOTOXIC EFFECT ON PANCREATIC CANCER CELLS IN VITRO', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2015) [E3]
Co-authors Adam Mccluskey, Michael Bowyer, C Scarlett
2014 Bond DR, Passfield C, Cairns M, Ashman LK, Weidenhofer J, 'Posttranscriptional regulation of tetraspanins CD151 & CD9 in breast & prostate cancers', CANCER RESEARCH (2014) [E3]
DOI 10.1158/1538-7445.AM2014-4364
Co-authors Leonie Ashman, Murray Cairns
2014 Sadeqzadeh E, Vuong QV, Goldsmith CD, Nguyen VT, Bhuyan DJ, Trung TD, et al., 'A NATURAL PRODUCT DRUG DISCOVERY PIPELINE FOR NOVEL PANCREATIC CANCER THERAPIES: A NEW CANCER RESEARCH HUB FOR THE HUNTER REGION OF NSW', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2014) [E3]
Co-authors Anita Chalmers, Vanquan Vuong, Rick Thorne, C Scarlett, Michael Bowyer, Troy Gaston, Natalie Moltschaniwskyj
2013 Weidenhofer J, Bond D, Copeland B, Ashman L, 'Tetraspanin protein turnover rates vary in prostate cancer cell lines', BJU INTERNATIONAL (2013) [E3]
Co-authors Leonie Ashman
2013 Bond D, Cairns M, Ashman L, Weidenhofer J, 'Post-transcriptional regulation of CD151 & CD9 by miRNAs in prostate cancer', BJU INTERNATIONAL (2013) [E3]
Co-authors Leonie Ashman, Murray Cairns
2012 Bond DR, Cairns MJ, Ashman LK, Weidenhofer JC, 'Investigating micro-RNA regulation of tetraspanins CD151 and CD9 in prostate cancer', Febs Journal (2012) [E3]
Co-authors Leonie Ashman, Murray Cairns
2011 Naudin C, Weidenhofer JC, Scott R, Ashman LK, Roselli SM, 'Induction of mindin expression is associated with glomerular basement membrane damage in Cd151(-/-) mice', Nephrology (2011) [E3]
Co-authors Leonie Ashman, Rodney Scott
2006 Weidenhofer JC, Bowden NA, Scott R, Tooney PA, 'Dysfunction of genes regulating membrane exocytosis in schizophrenia (Poster presentation)', Australian and New Zealand Journal of Psychiatry (Vol 40, noS2) (2006) [E3]
Co-authors Paul Tooney, Nikola Bowden, Rodney Scott
2005 Bowden NA, Weidenhofer JC, Scott R, Schall UA, Todd J, Michie PT, Tooney PA, 'Classification of schizophrenia using differential gene expression in peripheral blood lymphocytes', Human Genetics Society of Australasia (2005) [E3]
Co-authors Pat Michie, Ulrich Schall, Nikola Bowden, Rodney Scott, Juanita Todd, Paul Tooney
2004 Bowden NA, Weidenhofer JC, Scott R, Todd J, Case V, Schall UA, Tooney PA, 'Altered Expression of Brain Related Genes in Lymphocytes in Schizophrenia', American Journal of Medical Genetics (2004) [E3]
DOI 10.1002/ajmg.b.30101
Co-authors Ulrich Schall, Rodney Scott, Nikola Bowden, Paul Tooney, Juanita Todd
2004 Weidenhofer JC, Bowden NA, Scott R, Tooney PA, 'Gene Profiling in the Amygdala in Schizophrenia', American Journal of Medical Genetics (2004) [E3]
Co-authors Paul Tooney, Rodney Scott, Nikola Bowden
2004 Bowden NA, Weidenhofer JC, Scott R, Todd J, Case V, Schall UA, Tooney PA, 'Differental Gene Expression in Peripheral Blood Lymphocytes in Schizophrenia', Proceedings of the Australian Neuroscience Society (2004) [E3]
Co-authors Paul Tooney, Juanita Todd, Ulrich Schall, Rodney Scott, Nikola Bowden
2004 Weidenhofer JC, Bowden NA, Scott R, Tooney PA, 'Altered Gene Expression Profiles in the Amygdala in Schizophrenia', Proceedings of the Australian Neuroscience Society (2004) [E3]
Co-authors Rodney Scott, Paul Tooney, Nikola Bowden
2004 Bowden NA, Weidenhofer JC, Scott R, Todd J, Case V, Schall UA, Tooney PA, 'Distinct Gene Expression Profiles due to Age in Schizophrenia', Proceedings of the Australian Neuroscience Society (2004) [E3]
Co-authors Nikola Bowden, Rodney Scott, Ulrich Schall, Juanita Todd, Paul Tooney
Show 16 more conferences
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Grants and Funding

Summary

Number of grants 14
Total funding $1,040,045

Click on a grant title below to expand the full details for that specific grant.


20161 grants / $5,000

Equipment Grant: Developing Synthetic Exosomes to Target and Deliver Anti-Cancer Agents to Prostate Cancer$5,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Mr Joshua Brzozowski, Doctor Jude Weidenhofer, Doctor Kathryn Skelding, Associate Professor Christopher Scarlett
Scheme Project Grant
Role Lead
Funding Start 2016
Funding Finish 2016
GNo G1601042
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20145 grants / $503,199

Tetraspanin CD9; more than just an exosome marker - A novel biomarker to target for prostate cancer$300,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Jude Weidenhofer, Doctor Kathryn Skelding, Doctor Matt Dun, Ms BELINDA Goldie, Miss Danielle Bond
Scheme Project Grant
Role Lead
Funding Start 2014
Funding Finish 2016
GNo G1400921
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Visualisation of microparticles for development of biomarkers and targeted drug delivery mechanisms$125,199

Funding body: Cancer Institute NSW

Funding body Cancer Institute NSW
Project Team Associate Professor Christopher Scarlett, Doctor Kathryn Skelding, Doctor Jude Weidenhofer, Doctor Matt Dun, Doctor Kelly Kiejda, Professor Adam McCluskey, Ms Elham Sadeqzadeh, Professor Hubert Hondermarck, Doctor Rick Thorne, Professor Rodney Scott
Scheme Research Equipment Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1400627
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y

Developing Synthetic Exosomes to Target and Deliver Anti-Cancer Agents to Prostate Cancer Cells$37,500

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Mr Joshua Brzozowski, Doctor Jude Weidenhofer, Doctor Kathryn Skelding
Scheme Postgraduate Research Scholarship
Role Lead
Funding Start 2014
Funding Finish 2016
GNo G1401405
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

Identification and evaluation of anti-pancreatic cancer activity of cytotoxic compounds extracted from Australian sea sponges: a pilot study$20,500

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Associate Professor Christopher Scarlett, Doctor Quan Vuong, Doctor Jude Weidenhofer, Doctor Rick Thorne, Associate Professor Michael Bowyer, Doctor Troy Gaston
Scheme Project Grant
Role Investigator
Funding Start 2014
Funding Finish 2015
GNo G1401452
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

A new frontier in breast cancer: Can small molecules in the blood predict outcome?$20,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Kelly Kiejda, Doctor Jude Weidenhofer, Professor Rodney Scott
Scheme Project Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo G1401454
Type Of Funding Grant - Aust Non Government
Category 3AFG
UON Y

20131 grants / $24,596

20123 grants / $63,250

Microscopic illumination system for advanced fluorescent protein technology$34,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Rick Thorne, Professor Xu Dong Zhang, Conjoint Associate Professor Murray Cairns, Doctor Nikki Verrills, Doctor Charles De Bock, Doctor Jude Weidenhofer, Doctor Severine Roselli, Doctor Kathryn Skelding, Emeritus Professor Leonie Ashman, Professor Hubert Hondermarck
Scheme Equipment Grant
Role Investigator
Funding Start 2012
Funding Finish 2012
GNo G1100983
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

Does Ubiquitination control the altered expression of tetraspanin proteins in Breast Cancer?$25,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Jude Weidenhofer, Emeritus Professor Leonie Ashman, Professor Hubert Hondermarck
Scheme Project Grant
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1200169
Type Of Funding Contract - Aust Non Government
Category 3AFC
UON Y

PULSE - Education Prize$4,250

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Jude Weidenhofer
Scheme PULSE Education Prize
Role Lead
Funding Start 2012
Funding Finish 2012
GNo G1200157
Type Of Funding Scheme excluded from IGS
Category EXCL
UON Y

20113 grants / $410,000

Identifying the mechanisms underlying altered expression and mode of action of tetraspanins CD151 and CD9 in metastasis: progression to targeted treatment for prostate cancer$375,000

Funding body: Prostate Cancer Foundation of Australia

Funding body Prostate Cancer Foundation of Australia
Project Team Emeritus Professor Leonie Ashman, Doctor Jude Weidenhofer
Scheme Project Grant
Role Lead
Funding Start 2011
Funding Finish 2013
GNo G1000863
Type Of Funding Aust Competitive - Non Commonwealth
Category 1NS
UON Y

Investigation of the function of CD151 in the glomerular filtration barrier and identification of genetic modifiers of glomerular diseases$25,000

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Severine Roselli, Doctor Jude Weidenhofer, Emeritus Professor Leonie Ashman
Scheme Near Miss Grant
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1001053
Type Of Funding Internal
Category INTE
UON Y

IMPLEN NanoPhotometer pearl$10,000

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Conjoint Associate Professor Murray Cairns, Associate Professor Paul Tooney, Professor Alan Brichta, Emeritus Professor John Rostas, Emeritus Professor Patricia Michie, Conjoint Professor Keith Jones, Professor Ulli Schall, Associate Professor Phillip Dickson, Doctor Frederick Walker, Doctor Rick Thorne, Associate Professor Chris Dayas, Doctor Nikki Verrills, Doctor Janet Bristow, Doctor Severine Roselli, Doctor Kathryn Skelding, Doctor Jude Weidenhofer, Associate Professor Liz Milward, Doctor Charles De Bock, Doctor Julie Merriman-Jones, Doctor Jing Qin Wu, Doctor Bing Liu, Dr DAN Johnstone, Ms BELINDA Goldie, Doctor Natalie Beveridge
Scheme Equipment Grant
Role Investigator
Funding Start 2011
Funding Finish 2011
GNo G1100030
Type Of Funding Other Public Sector - Commonwealth
Category 2OPC
UON Y

20101 grants / $34,000

ABI 7500 Real Time PCR System $34,000

Funding body: NHMRC (National Health & Medical Research Council)

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Research Supervision

Number of supervisions

Completed3
Current4

Total current UON EFTSL

PhD1.75

Current Supervision

Commenced Level of Study Research Title / Program / Supervisor Type
2016 PhD Targeting the S100A2 Axis as a Novel Therapeutic Target for Pancreatic Cancer
PhD (Biological Sciences), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2015 PhD Circulating Exosomes in Pancreatic Cancer as a Source of Novel Diagnostic Biomarkers
PhD (Biological Sciences), Faculty of Science and Information Technology, The University of Newcastle
Co-Supervisor
2014 PhD Identification of Biomarkers and Novel Targets for Prostate Cancer from Exosomes
PhD (Medical Biochemistry), Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2014 PhD Developing Synthetic Exosomes to Target and Deliver Anti-Cancer Agents to Prostate Cancer Cells
PhD (Medical Biochemistry), Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor

Past Supervision

Year Level of Study Research Title / Program / Supervisor Type
2015 PhD The Tetraspanin CD151's Role in the Kidney and Mapping of Genetic Modifiers of Glomerular Diseases
PhD (Medical Biochemistry), Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2015 PhD Post-Transcriptional Regulation of Tetraspanins CD151 and CD9 by Micro-RNAs in Prostate and Breast Cancers
PhD (Medical Biochemistry), Faculty of Health and Medicine, The University of Newcastle
Principal Supervisor
2013 PhD Tetraspanins as Biomarkers and Causative Proteins in Prostate Cancer
PhD (Medical Biochemistry), Faculty of Health and Medicine, The University of Newcastle
Co-Supervisor
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Dr Jude Weidenhofer

Position

Lecturer
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine

Focus area

Medical Biochemistry

Contact Details

Email judith.weidenhofer@newcastle.edu.au
Phone (02) 4921 8706
Fax (02) 43494538

Office

Room BE136
Building Health Precinct
Location Ourimbah
10 Chittaway Road
Ourimbah, NSW 2258
Australia
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