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Associate Professor David McCurdy

Associate Professor

School of Environmental and Life Sciences (Biological Sciences)

Career Summary

Biography

Significant contributions to research field: Transfer cell research: My contributions relative to this project are as a senior member of a team at Newcastle (with CI 2 A/Prof Christina Offler and including Prof John Patrick) producing internationally-competitive research on plant transfer cells. My research has used cell biological and EM techniques (Bulbert et al 1998 Protoplasma 201: 8-16; Talbot et al 2001, 2002, 2007; Vaughn et al 2007)) to provide new insights into the unique morphology of wall ingrowths in transfer cells, and is now using molecular genomics techniques to unravel the molecular regulation of both the induction of transfer cells (DP0664626 JP, DMcC, CO) and the building of reticulate papillate wall ingrowths (DP0556217 CO, DMcC; and this application). Our team is internationally recognized in this field of research as evidenced by invitation to author a major review on transfer cells (Offler et al 2003, Ann. Rev. Plant Biol.). My specific input into studying transfer cell development includes co-supervising with A/P Offler the development of the dry-cleave procedure to visualize wall ingrowth morphology by SEM. This technique was instrumental in obtaining a detailed morphological understanding of how the complex wall ingrowth apparatus originates from discrete papillate projections of the parent wall (Talbot et al 2001), unlike other examples of localized wall deposition in plants, such as secondary wall thickenings. This technique was also used to define different categories of wall ingrowth morphology in transfer cells across the plant kingdom (Talbot et al 2002), and was used in our recent publication using Field Emission SEM to document for the first time a novel form of cellulose deposition which marks the initiation of wall ingrowth deposition (Talbot et al 2007). The use of this dry-cleave technique and related methodologies will contribute to achieving aspects of Aims 2 and 3 in this current application. My experience in molecular biology has also contributed heavily to successfully guiding implementation of the cDNA-AFLP which is identifying the complex levels of transcriptional regulation accompanying transfer cell development (see E3.4). When published, this new understanding of transfer cell biology will establish a paradigm shift in this field, away from the concept of identifying transfer cell-specific genes. Other evidence of impact and contributions to the field: Postgraduate Training: In the last 5 years I have co-supervised 4 PhD students to completion (Gear, Dibley, Talbot, Sheahan) each producing on average 3 major publications per thesis. One student (Sheahan) has been awarded an ARC-Post Doctoral Fellowship (2007-2009) to continue his research at Newcastle on organelle inheritance. Across this time I have also supervised or co-supervised 5 Honours students and two Masters students. Conference Participation: I have a strong record of conference participation (48 abstracts since 1993), both national (ASPP, Annual General Meeting) and international (AmSPP, ICATP, Gordon Conf.), and presented invited Keynote lecture at Robertson Symp., Feb. 2000, Canberra. Conference Organization: In my capacity as Cell Biology Rep (2007- ) for the Australian Society of Plant Physiologists (ASPP), I am on the ASPP Organizing Committee for ComBio 2007 (Sydney). This includes chairing the Symposia on Plant Cell Dynamics at this meeting. Refereeing: I regularly referee for leading plant science journals (Plant Cell, Plant Journal, Plant Physiology, Planta, Functional Plant Biology, Protoplasma, Journal of Experimental Botany, Plant & Cell Physiol.) and have reviewed papers for both Cell Motil. Cytoskeleton and J. Neurobiology. I am regularly requested to review for national (ARC av. 2 grants/yr) and international granting agencies (NSF and USDA- av. 1.5 grants/yr for both; BSF, United States-Israel Binational Science Foundation). I have accepted the invitation from ARC to be an OzReader for 2007. My contributions to the field of the plant cytoskeleton have been recognized by invitations to speak at the Gordon Conference on Plant and Fungal Cytoskeleton both personally and as a collaborative partner with Prof. CJ Staiger. I was invited to present a Keynote Address to the Robertson Symposium on Plant Cell Biology (Feb. 2000) to mark the retirement of Prof. B.E.S Gunning. I have been invited to write several reviews on the plant actin cytoskeleton, the most recent being a chapter contributing to an edited book on this topic (Actin: A Dynamic Framework For Multiple Plant Cell Functions. eds: CJ Staiger, F Baluska, D Volkmann & P Barlow) which has become a landmark text in this field. Aspects of career: Biotechnology Hexose transporters in tomato: With Prof. John Patrick (Plant Science Group, University of Newcastle) I have investigated the molecular biology of hexose transporters in developing tomato fruit. This research was supported by an ARC Large Grant (1996-1998) and more recently by an ARC-SPIRT Grant (2001-2004). This research has resulted to this point in two publications (Gear et al 2000, Dibley et al 2005) and establishment of an Australian Provisional Patent (#2006906647 Plants with increased hexose content Patrick, Dibley & McCurdy). Following establishment of the provisional patent (filing date: Nov 28, 2006), we are now preparing two manuscripts detailing this research. One, using RNAi technology, demonstrates for the first time the role of hexose transporters in regulating hexose uptake into tomato fruit, will be submitted to Plant Cell, while the second, using overexpression of heterologous transporters to achieve elevated hexose concentration in fruits, will be submitted to Nature Biotechnology. Mechanisms of organelle inheritance in plants: I have also established a successful collaboration with A/Prof Ray Rose (Plant Science Group, University of Newcastle) investigating cytoskeletal regulation of organelle inheritance during plant cell division. This study formed the PhD research of Mr Michael Sheahan, and has provided the first evidence that plants use tightly regulated mechanisms to achieve accurate organelle partitioning at cell division. This research has resulted in 4 publications (Sheahan et al 2004a, 2004b, 2005, 2007) two reviews (Rose et al 2006a, 2006b, the latter an invited contribution to Encyclopedia of Life Sciences), and a third review (invited) in preparation. The Plant Journal paper has attracted widespread interest and was reviewed as a Faculty of 1000 publication (see B10.3), and the Plant Physiology paper introduced a new tool to visualize actin dynamics in plants which has now been adopted by the research community as the best available probe for this purpose.

Research Expertise

Research expertise in plant cell and molecular biology, focusing on the plant cytoskelton, cell wall and mamebrane transporters.

Teaching Expertise
Plant Cell and Molecular Biology, Plant Cell Development, Biomolecules, Advanced Laboratory Skills

Administrative Expertise
Student Academic Conduct Officer, Scholl of Environmental and Life Sciences 



Qualifications

  • PhD, La Trobe University
  • Bachelor of Science (Honours), La Trobe University

Keywords

  • Plant cell and molecular biology

Fields of Research

CodeDescriptionPercentage
060199Biochemistry and Cell Biology not elsewhere classified15
060299Ecology not elsewhere classified15
060702Plant Cell and Molecular Biology70

Professional Experience

UON Appointment

DatesTitleOrganisation / Department
1/01/2014 - Associate ProfessorUniversity of Newcastle
School of Environmental and Life Sciences
Australia

Academic appointment

DatesTitleOrganisation / Department
1/11/1992 - Senior LecturerUniversity of Newcastle
School of Environmental and Life Sciences
Australia

Membership

DatesTitleOrganisation / Department
Member - American Society of Plant BiologistsAmerican Society of Plant Biologists
United States
Cell Biology RepresentativeAustralian Society of Plant Scientists
Australia
Member - The Japanese Society of Plant PhysiologistsThe Japanese Society of Plant Physiologists
Japan
1/01/2007 - 31/12/2007Member - Organising Committee, ASPS ComBioAustralian Society of Plant Scientists
Australia
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (10 outputs)

YearCitationAltmetricsLink
2015McCurdy DW, 'Transfer Cells: Novel Cell Types with Unique Wall Ingrowth Architecture Designed for Optimized Nutrient Transport', Plant Cell Wall Patterning and Cell Shape, Wiley Blackwell, Hoboken, NJ 287-317 (2015)
DOI10.1002/9781118647363.ch11
2014McCurdy DW, 'Transfer Cells: Novel Cell Types with Unique Wall Ingrowth Architecture Designed for Optimized Nutrient Transport', Plant Cell Wall Patterning and Cell Shape, Wiley Blackwell 287-317 (2014)

Transfer cells provide a fascinating example of how the cell wall profoundly influences cell function in plants. As the name implies, transfer cells (TCs) are involved in nutrient transport events where nutrients pass across a plasma membrane at apoplasmic/symplasmic junctions in nutrient acquisition or delivery pathways. This chapter focuses primarily on describing wall ingrowth architecture in TCs and the numerous and unique variations that make these functionally important cell types so absorbing to study. It also describes the features of phloem parenchyma TCs in minor veins of the model species Arabidopsis thaliana (Arabidopsis) as a way forward to develop genetic approaches to study TC biology. Reticulate wall ingrowths are by far the most common wall ingrowth morphology seen in the plant kingdom. Flange wall ingrowths are characterized by deposition of curvilinear, rib-shaped projections of wall material.

DOI10.1002/9781118647363.ch11
2007Rose RJ, McCurdy DW, Sheahan MB, 'Plant mitochondria', Encyclopedia of Life Sciences, Nature Publishing Group, London 1-8 (2007)
2006Rose RJ, Fitter JT, McCurdy DW, Sheahan MB, 'Mitochondrial Somatic Genetics and Homeotic Effects on Flower Morphology', Floriculture, Ornamental and Plant Biotechnology: advances and topical issues, Global Science Books, Isleworth, United Kingdom 210-215 (2006) [B1]
Co-authorsRay Rose, John Fitter
2000McCurdy DW, Staiger CJ, 'Fimbrin', Actin: A Dynamic Framework for Multiple Plant Cell Functions, Kluwer Academic Publishers, Dordrecht 87-101 (2000)
1991McCurdy DW, Williamson RE, 'Actin and associated proteins', The Cytoskeletal Basis of Plant Growth and Form, Academic Press, London 3-14 (1991)
1990Harmon AC, 'Calcium dependent protein kinase and its possible role in the regulation of the cytoskeleton', Current Topics in Plant Biochemistry and Physiology, University of Missouri, Columbia 119-128 (1990)
1989Williamson RE, McCurdy DW, Grolig F, Hurley UA, Jablonski PP, Wasteneys GO, 'Methods for studying the plant cytoskeleton', Modern Methods of Plant Analysis, New Series, Springer-Verlag, Berlin 203-218 (1989)
1988Wampler JE, Chen J, DeMendoza LG, Furukawa RH, McCurdy DW, Pruett L, et al., 'Strategies for spatially resolved microspectrofluorometric analysis', Time Resolved Laser Spectroscopy in Biochemistry, Proceedings of SPIE The International Society for Optical Engineering, The International Society for Optical Engineering, New York 319-327 (1988)
1986Pratt LH, McCurdy DW, Shimazaki Y, Cordonnier M-M, 'Immunodetection of phytochrome: immunocytochemistry, immunoblotting, and immunoquantification', Modern Methods of Plant Analysis, New Series, Springer-Verlag, Berlin 50-74 (1986)
Show 7 more chapters

Journal article (52 outputs)

YearCitationAltmetricsLink
2015Zhang H-M, Imtiaz MS, Laver DR, McCurdy DW, Offler CE, Van Helden DF, Patrick JW, 'Polarized and persistent Ca2+ plumes define loci for formation of wall ingrowth papillae in transfer cells', Journal of Experimental Botany, 66 1179-1190 (2015)

Transfer cell morphology is characterized by a polarized ingrowth wall comprising a uniform wall upon which wall ingrowth papillae develop at right angles into the cytoplasm. The hypothesis that positional information directing construction of wall ingrowth papillae is mediated by Ca2+ signals generated by spatiotemporal alterations in cytosolic Ca2+ ([Ca2+]cyt) of cells trans-differentiating to a transfer cell morphology was tested. This hypothesis was examined using Vicia faba cotyledons. On transferring cotyledons to culture, their adaxial epidermal cells synchronously trans-differentiate to epidermal transfer cells. A polarized and persistent Ca2+ signal, generated during epidermal cell trans-differentiation, was found to co-localize with the site of ingrowth wall formation. Dampening Ca2+ signal intensity, by withdrawing extracellular Ca2+ or blocking Ca2+ channel activity, inhibited formation of wall ingrowth papillae. Maintenance of Ca2+ signal polarity and persistence depended upon a rapid turnover (minutes) of cytosolic Ca2+ by co-operative functioning of plasma membrane Ca2+-permeable channels and Ca2+-ATPases. Viewed paradermally, and proximal to the cytosol-plasma membrane interface, the Ca2+ signal was organized into discrete patches that aligned spatially with clusters of Ca2+-permeable channels. Mathematical modelling demonstrated that these patches of cytosolic Ca2+ were consistent with inward-directed plumes of elevated [Ca2+]cyt. Plume formation depended upon an alternating distribution of Ca2+-permeable channels and Ca2+-ATPase clusters. On further inward diffusion, the Ca2+ plumes coalesced into a uniform Ca2+ signal. Blocking or dispersing the Ca2+ plumes inhibited deposition of wall ingrowth papillae, while uniform wall formation remained unaltered. A working model envisages that cytosolic Ca2+ plumes define the loci at which wall ingrowth papillae are deposited.

DOI10.1093/jxb/eru460
CitationsScopus - 1Web of Science - 3
Co-authorsDerek Laver, John Patrick, Dirk Vanhelden
2015Wolfenstetter S, Chakravorty D, Kula R, Urano D, Trusov Y, Sheahan MB, et al., 'Evidence for an unusual transmembrane configuration of AGG3, a class C G¿ subunit of Arabidopsis', Plant Journal, 81 388-398 (2015)

Heterotrimeric G proteins are crucial for the perception of external signals and subsequent signal transduction in animal and plant cells. In both model systems, the complex comprises one Ga, one Gß, and one G¿ subunit. However, in addition to the canonical G¿ subunits (class A), plants also possess two unusual, plant-specific classes of G¿ subunits (classes B and C) that have not yet been found in animals. These include G¿ subunits lacking the C-terminal CaaX motif (class B), which is important for membrane anchoring of the protein; the presence of such subunits gives rise to a flexible sub-population of Gß/¿ heterodimers that are not necessarily restricted to the plasma membrane. Plants also contain class C G¿ subunits, which are twice the size of canonical G¿ subunits, with a predicted transmembrane domain and a large cysteine-rich extracellular C-terminus. However, neither the presence of the transmembrane domain nor the membrane topology have been unequivocally demonstrated. Here, we provide compelling evidence that AGG3, a class C G¿ subunit of Arabidopsis, contains a functional transmembrane domain, which is sufficient but not essential for plasma membrane localization, and that the cysteine-rich C-terminus is extracellular. Significance Statement AGG3 is the prototype of an unusual G¿ subunit of the heterotrimeric G protein complex. It is a type II membrane protein having a cysteine-rich extracellular domain.

DOI10.1111/tpj.12732
CitationsScopus - 2
2015Arun-Chinnappa KS, McCurdy DW, 'De novo assembly of a genome-wide transcriptome map of Vicia faba (L.) for transfer cell research', FRONTIERS IN PLANT SCIENCE, 6 (2015)
DOI10.3389/fpls-2015.00217Author URL
2015Nguyen ST, McCurdy DW, 'High-resolution confocal imaging of wall ingrowth deposition in plant transfer cells: Semi-quantitative analysis of phloem parenchyma transfer cell development in leaf minor veins of Arabidopsis.', BMC Plant Biol, 15 109 (2015)
DOI10.1186/s12870-015-0483-8Author URL
2015Arun-Chinnappa KS, McCurdy DW, 'De novo assembly of a genome-wide transcriptome map of Vicia faba (L) for transfer cell research', Frontiers in Plant Science, 6 (2015)

Vicia faba (L.) is an important cool-season grain legume species used widely in agriculture but also in plant physiology research, particularly as an experimental model to study transfer cell (TC) development. TCs are specialized nutrient transport cells in plants, characterized by invaginated wall ingrowths with amplified plasma membrane surface area enriched with transporter proteins that facilitate nutrient transfer. Many TCs are formed by trans-differentiation from differentiated cells at apoplasmic/symplasmic boundaries in nutrient transport. Adaxial epidermal cells of isolated cotyledons can be induced to form functional TCs, thus providing a valuable experimental system to investigate genetic regulation of TC trans-differentiation. The genome of V. faba is exceedingly large (ca. 13 Gb), however, and limited genomic information is available for this species. To provide a resource for future transcript profiling of epidermal TC differentiation, we have undertaken de novo assembly of a genome-wide transcriptome map for V faba. Illumina paired-end sequencing of total RNA pooled from different tissues and different stages, including isolated cotyledons induced to form epidermal TCs, generated 69.5 M reads, of which 65.8 M were used for assembly following trimming and quality control. Assembly using a De-Bruijn graph-based approach generated 21,297 contigs, of which 80.6% were successfully annotated against GO terms. The assembly was validated against known V faba cDNAs held in GenBank, including transcripts previously identified as being specifically expressed in epidermal cells across TC trans-differentiation. This genome-wide transcriptome map therefore provides a valuable tool for future transcript profiling of epidermal TC trans-differentiation, and also enriches the genetic resources available for this important legume crop species.

DOI10.3389/fpls.2015.00217
2014Wolfenstetter S, Chakravorty D, Kula R, Urano D, Trusov Y, Sheahan MB, et al., 'Evidence for an unusual transmembrane configuration of AGG3, a class C G¿ subunit of Arabidopsis', Plant Journal, (2014)

Heterotrimeric G proteins are crucial for the perception of external signals and subsequent signal transduction in animal and plant cells. In both model systems, the complex comprises one Ga, one Gß, and one G¿ subunit. However, in addition to the canonical G¿ subunits (class A), plants also possess two unusual, plant-specific classes of G¿ subunits (classes B and C) that have not yet been found in animals. These include G¿ subunits lacking the C-terminal CaaX motif (class B), which is important for membrane anchoring of the protein; the presence of such subunits gives rise to a flexible sub-population of Gß/¿ heterodimers that are not necessarily restricted to the plasma membrane. Plants also contain class C G¿ subunits, which are twice the size of canonical G¿ subunits, with a predicted transmembrane domain and a large cysteine-rich extracellular C-terminus. However, neither the presence of the transmembrane domain nor the membrane topology have been unequivocally demonstrated. Here, we provide compelling evidence that AGG3, a class C G¿ subunit of Arabidopsis, contains a functional transmembrane domain, which is sufficient but not essential for plasma membrane localization, and that the cysteine-rich C-terminus is extracellular.

DOI10.1111/tpj.12732
2014McCurdy DW, Hueros G, 'Transfer cells', Frontiers in Plant Science, 5 (2014) [C3]
DOI10.3389/fpls.2014.00672
2013Chinnappa KSA, Nguyen TTS, Hou J, Wu Y, McCurdy DW, 'Phloem parenchyma transfer cells in Arabidopsis - an experimental system to identify transcriptional regulators of wall ingrowth formation', Frontiers in Plant Science, 4 (2013) [C1]
DOI10.3389/fpls.2013.00102Author URL
CitationsScopus - 8Web of Science - 6
2012Andriunas FA, Zhang H, Xia X, Offler CE, McCurdy DW, Patrick JW, 'Reactive oxygen species form part of a regulatory pathway initiating trans-differentiation of epidermal transfer cells in Vicia faba cotyledons', Journal of Experimental Botany, 63 3617-3630 (2012) [C1]
CitationsScopus - 16Web of Science - 15
Co-authorsTina Offler, John Patrick
2011Chakravorty D, Trusov Y, Zhang W, Acharya BR, Sheahan MB, McCurdy DW, et al., 'An atypical heterotrimeric G-protein gamma-subunit is involved in guard cell K(+)-channel regulation and morphological development in Arabidopsis thaliana', The Plant Journal, 67 840-851 (2011) [C1]
DOI10.1111/j.1365-313X.2011.04638.x
CitationsScopus - 51Web of Science - 44
2011Andriunas FA, Zhang H, Weber H, McCurdy DW, Offler CE, Patrick JW, 'Glucose and ethylene signalling pathways converge to regulate trans-differentiation of epidermal transfer cells in Vicia narbonensis cotyledons', The Plant Journal, 68 987-998 (2011) [C1]
CitationsScopus - 12Web of Science - 10
Co-authorsJohn Patrick, Tina Offler
2010McCurdy DW, Dibley SJ, Cahyanegara R, Martin A, Patrick JW, 'Functional characterization and RNAi-mediated suppression reveals roles for hexose transporters in sugar accumulation by tomato fruit', Molecular Plant, 3 1049-1063 (2010) [C1]
DOI10.1093/mp/ssq050
CitationsScopus - 21Web of Science - 19
Co-authorsJohn Patrick
2010Zhou Y, Andriunas FA, Offler CE, McCurdy DW, Patrick JW, 'An epidermal-specific ethylene signal cascade regulates trans-differentiation of transfer cells in Vicia faba cotyledons', New Phytologist, 185 931-943 (2010) [C1]
DOI10.1111/j.1469-8137.2009.03136.x
CitationsScopus - 14Web of Science - 13
Co-authorsJohn Patrick, Tina Offler
2010Edwards J, Martin A, Andriunas FA, Offler CE, Patrick JW, McCurdy DW, 'GIGANTEA is a component of a regulatory pathway determining wall ingrowth deposition in phloem parenchyma transfer cells of Arabidopsis thaliana', The Plant Journal, 63 651-661 (2010) [C1]
DOI10.1111/j.1365-313x.2010.04269.x
CitationsScopus - 16Web of Science - 14
Co-authorsTina Offler, John Patrick
2009Staiger CJ, Sheahan MB, Khurana P, Wang X, McCurdy DW, Blanchoin L, 'Actin filament dynamics are dominated by rapid growth and severing activity in the Arabidopsis cortical array', Journal of Cell Biology, 184 269-280 (2009) [C1]
DOI10.1083/jcb.200806185
CitationsScopus - 107Web of Science - 104
2009Dibley SJ, Zhou Y, Andriunas FA, Talbot MJ, Offler CE, Patrick JW, McCurdy DW, 'Early gene expression programs accompanying trans-differentiation of epidermal cells of Vicia faba cotyledons into transfer cells', New Phytologist, 182 863-877 (2009) [C1]
DOI10.1111/j.1469-8137.2009.02822.x
CitationsScopus - 20Web of Science - 18
Co-authorsTina Offler, John Patrick
2008McCurdy DW, Patrick JW, Offler CE, 'Wall ingrowth formation in transfer cells: Novel examples of localized wall deposition in plant cells', Current Opinion in Plant Biology, 11 653-661 (2008) [C1]
DOI10.1016/j.pbi.2008.08.005
CitationsScopus - 32Web of Science - 31
Co-authorsTina Offler, John Patrick
2007Talbot MJ, Wasteneys G, McCurdy DW, Offler CE, 'Deposition patterns of cellulose microfibrils in flange wall ingrowths of transfer cells indicate clear parallels with those of secondary wall thickenings', Functional Plant Biology, 34 307-313 (2007) [C1]
DOI10.1071/fp06273
CitationsScopus - 11Web of Science - 11
Co-authorsTina Offler
2007Sheahan MB, Rose RJ, McCurdy DW, 'Mechanisms of organelle inheritance in dividing plant cells', Journal of Integrative Plant Biology, 49 1208-1218 (2007) [C1]
DOI10.1111/j.1672-9072.2007.00523.x
CitationsScopus - 8Web of Science - 7
Co-authorsRay Rose
2007Vaughn KC, Talbot MJ, Offler CE, McCurdy DW, 'Wall ingrowths in epidermal transfer cells of Vicia faba cotyledons are modified primary walls marked by localized accumulations of arabinogalactan proteins', Plant and Cell Physiology, 48 159-168 (2007) [C1]
DOI10.1093/pcp/pcl047
CitationsScopus - 33Web of Science - 32
Co-authorsTina Offler
2007Talbot MJ, Wasteneys GO, Offler CE, McCurdy DW, 'Cellulose synthesis is required for deposition of reticulate wall ingrowths in transfer cells', Plant and Cell Physiology, 48 147-158 (2007) [C1]
DOI10.1093/pcp/pcl046
CitationsScopus - 17Web of Science - 20
Co-authorsTina Offler
2007Sheahan MB, Rose RJ, McCurdy DW, 'Actin-filament-dependent remodeling of the vacuole in cultured mesophyll protoplasts', Protoplasma, 230 141-152 (2007) [C1]
DOI10.1007/s00709-006-0236-5
CitationsScopus - 25Web of Science - 24
Co-authorsRay Rose
2005Sheahan MB, McCurdy DW, Rose RJ, 'Mitochondria as a connected population: ensuring continuity of the mitochondrial genome during plant cell dedifferentiation through massive mitochondrial fusion', The Plant Journal, 44 744-755 (2005) [C1]
DOI10.1111/j.1365-313X.2005.02561.x
CitationsScopus - 69Web of Science - 68
Co-authorsRay Rose
2005Dibley SJ, Gear ML, Yang X, Rosche E, Offler CE, McCurdy DW, Patrick JW, 'Temporal and spatial expression of hexose transporters in developing tomato (Lycopersicon esculentum) fruit', Functional Plant Biology, 32 777-785 (2005) [C1]
DOI10.1071/FP04224
CitationsScopus - 12Web of Science - 10
Co-authorsTina Offler, John Patrick
2005Baluska F, Liners F, Hlavacka A, Schlicht M, Van Cutsem P, McCurdy DW, Menzel D, 'Cell wall pectins and xyloglucans are internalized into dividing root cells and accumulate within cell plates during cytokinesis', Protoplasma, 225 141-155 (2005) [C1]
DOI10.1007/s00709-005-0095-5
CitationsScopus - 61Web of Science - 51
2004Sheahan MB, Staiger C, Rose RJ, McCurdy DW, 'A Green Fluorescent Protein Fusion to Actin-Binding Domain 2 of Arabidopsis Fimbrin Highlights New Features of a Dynamic Actin Cytoskeleton in Live Plant Cells', Plant Physiology, 136 3968-3978 (2004) [C1]
DOI10.1104/pp.104.049411
CitationsScopus - 140Web of Science - 135
Co-authorsRay Rose
2004Sheahan MB, Rose RJ, McCurdy DW, 'Organelle inheritance in plant cell division: the actin cytoskeleton is required for unbiased inheritance of chloroplasts, mitochondria and endoplasmic reticulum in dividing protoplasts', Plant Journal, 37 379-390 (2004) [C1]
DOI10.1046/j.1365-313X.2003.01967.x
CitationsScopus - 90Web of Science - 88
Co-authorsRay Rose
2003Offler CE, McCurdy DW, Patrick JW, Talbot MJ, 'Transfer Cells: Cells Specialized for a Special Purpose', Annual Review of Plant Biology, 54 431-454 (2003) [C1]
DOI10.1146/annurev.arplant.54.031902.134812
CitationsScopus - 138Web of Science - 124
Co-authorsJohn Patrick, Tina Offler
2002Baluska F, Hlavacka A, Samaj J, Palme K, Robinson D, Matoh T, et al., 'F-actin-dependent endocytosis of cell wall pectins in meristematic root cells. Insights from Brefeldin A-induced compartments', Plant Physiology, 130 422-431 (2002) [C1]
CitationsScopus - 169Web of Science - 155
2002Talbot MJ, Offler CE, McCurdy DW, 'Transfer cell wall architecture: a contribution towards understanding localized wall deposition', Protoplasma, 219 197-209 (2002) [C1]
CitationsScopus - 38Web of Science - 36
Co-authorsTina Offler
2001Kovar DR, Gibbon BC, McCurdy DW, Staiger CJ, 'Fluorescently-labeled fimbrin decorates a dynamic actin filament network in live plant cells', Planta, 213 390-395 (2001) [C1]
CitationsScopus - 40Web of Science - 37
2001McCurdy DW, Kovar DR, Staiger CJ, 'Actin and actin-binding proteins in higher plants', Protoplasma, 215 89-104 (2001) [C1]
CitationsScopus - 56Web of Science - 52
2001Talbot MJ, Franceschi VR, McCurdy DW, Offler CE, 'Wall ingrowth architecture in epidermal transfer cells of Vicia faba cotyledons', Protoplasma, 215 191-203 (2001) [C1]
CitationsScopus - 31Web of Science - 30
Co-authorsTina Offler
2000Gear ML, McPhillips ML, Patrick JW, McCurdy DW, 'Hexose transporters of tomato:molecular cloning, expression analysis and functional characterization', PLANT MOLECULAR BIOLOGY, 44 687-697 (2000) [C1]
CitationsScopus - 35Web of Science - 33
Co-authorsJohn Patrick
2000Kovar DR, Staiger CJ, Weaver EA, McCurdy DW, 'AtFim1 is an actin filament crosslinking protein from Arabidopsis thaliana', THE PLANT JOURNAL, 24 (5) 625-636 (2000) [C1]
CitationsScopus - 88Web of Science - 87
1999McCurdy DW, 'Is 2,3-butanedione monoxime an effective inhibitor of myosin-based activities in plant cells?', Protoplasma, 209 120-125 (1999) [C1]
CitationsScopus - 37Web of Science - 35
1998McCurdy DW, Kim S-Y, 'Molecular cloning of a novel fimbrin-like cDNA from Arabidopsis thaliana', Plant Molecular Biology, 36 23-31 (1998) [C1]
CitationsScopus - 52Web of Science - 52
1998Bulbert MW, Offler CE, McCurdy DW, 'Polarized microtubule deposition coincides with wall ingrowth formation in transfer cells of Vicia faba L. cotyledons', Protoplasma, 201 8-16 (1998) [C1]
CitationsScopus - 16Web of Science - 16
Co-authorsTina Offler
1992MCCURDY DW, HARMON AC, 'CALCIUM-DEPENDENT PROTEIN-KINASE IN THE GREEN-ALGA CHARA', PLANTA, 188 54-61 (1992)
DOI10.1007/BF01160712Author URL
CitationsWeb of Science - 44
1992McCurdy DW, Harmon AC, 'Calcium-dependent protein kinase in the green alga Chara', Planta, 188 54-61 (1992)

Cytoplasmic streaming in the characean algae is inhibited by micromolar rises in the level of cytosolic free Ca2+, but both the mechanism of action and the molecular components involved in this process are unknown. We have used monoclonal antibodies against soybean Ca2+-dependent protein kinase (CDPK), a kinase that is activated by micromolar Ca2+ and co-localizes with actin filaments in higher-plant cells (Putnam-Evans et al., 1989, Cell Motil. Cytoskel. 12, 12-22) to identify and localize its characean homologue. Immunoblot analysis revealed that CDPK in Chara corralina Klein ex. Wild shares the same relative molecular mass (51-55 kDa) as the kinase purified from soybean, and after electrophoresis in denaturing gels is capable of phosphorylating histone III-S in a Ca2+-dependent manner. Immunofluorescence microscopy localized CDPK in Chara to the subcortical actin bundles and the surface of small organelles and other membrane components of the streaming endoplasm. The endoplasmic sites carrying CDPK were extracted from internodal cells by vacuolar perfusion with 1 mM ATP or 10-4 M Ca2+. Both the localization of CDPK and its extraction from internodal cells by perfusion with ATP or high Ca2+ are properties similar to that reported for the heavy chain of myosin in Chara (Grolig et al., 1988, Eur. J. Cell Biol. 47, 22-31). Based on its endoplasmic location and inferred enzymatic properties, we suggest that CDPK may be a putative element of the signal-transduction pathway that mediates the rapid Ca2+-induced inhibition of streaming that occurs in the characean algae. © 1992 Springer-Verlag.

DOI10.1007/BF00198939
CitationsScopus - 30
1992MCCURDY DW, HARMON AC, 'PHOSPHORYLATION OF A PUTATIVE MYOSIN LIGHT CHAIN IN CHARA BY CALCIUM-DEPENDENT PROTEIN-KINASE', PROTOPLASMA, 171 85-88 (1992)
DOI10.1007/BF01379284Author URL
CitationsScopus - 15Web of Science - 22
1992HARPER JDI, MCCURDY DW, SANDERS MA, SALISBURY JL, JOHN PCL, 'ACTIN DYNAMICS DURING THE CELL-CYCLE IN CHLAMYDOMONAS-REINHARDTII', CELL MOTILITY AND THE CYTOSKELETON, 22 117-126 (1992)
DOI10.1002/cm.970220205Author URL
CitationsWeb of Science - 39
1991MCCURDY DW, PALEVITZ BA, GUNNING BES, 'EFFECT OF CYTOCHALASINS ON ACTIN IN DIVIDING ROOT-TIP CELLS OF ALLIUM AND TRITICUM - A COMPARATIVE IMMUNOCYTOCHEMICAL STUDY', CELL MOTILITY AND THE CYTOSKELETON, 18 107-112 (1991)
DOI10.1002/cm.970180205Author URL
CitationsScopus - 3Web of Science - 8
1990JOHN PCL, SEK FJ, CARMICHAEL JP, MCCURDY DW, 'P34CDC2 HOMOLOG LEVEL, CELL-DIVISION, PHYTOHORMONE RESPONSIVENESS AND CELL-DIFFERENTIATION IN WHEAT LEAVES', JOURNAL OF CELL SCIENCE, 97 627-630 (1990)
Author URL
CitationsScopus - 8Web of Science - 46
1990John PCL, Sek FJ, Carmichael JP, McCurdy DW, 'p34cdc2 homologue level, cell division, phytohormone responsiveness and cell differentiation in wheat leaves', Journal of Cell Science, 97 627-630 (1990)

Formation of a plant involves generation of new cells by the division cycle and development in these of specialised structure and metabolism. Specialisation is accompanied by a decreasing capacity for division, which declines with particular rapidity in cells of monocotyledonous plants such as the cereals. Here we report that in wheat leaves a homologue of the cell cycle control protein p34cdc2 participates in the control of these developmental programmes. Accumulation of p34cdc2 to a maximum level in dividing cells and the cessation of its accumulation during subsequent cell growth and expansion indicate that it contributes specifically to division. There is a decline in p34cdc2 level as cell differentiation proceeds, in close parallel with the previously established decline of cell division in response to auxin hormones. A basal level of p34cdc2 in fully differentiated cells that is one-sixteenth of that in dividing cells correlates with their loss of capacity to divide. We conclude that p34cdc2 level is controlled in diverse multicellular eukaryotes and suggest that it is an important element in the switch from cell division to differentiation.

CitationsScopus - 19
1990MCCURDY DW, GUNNING BES, 'REORGANIZATION OF CORTICAL ACTIN MICROFILAMENTS AND MICROTUBULES AT PREPROPHASE AND MITOSIS IN WHEAT ROOT-TIP CELLS - A DOUBLE LABEL IMMUNOFLUORESCENCE STUDY', CELL MOTILITY AND THE CYTOSKELETON, 15 76-87 (1990)
DOI10.1002/cm.970150204Author URL
CitationsScopus - 34Web of Science - 64
1988MCCURDY DW, SAMMUT M, GUNNING BES, 'IMMUNOFLUORESCENT VISUALIZATION OF ARRAYS OF TRANSVERSE CORTICAL ACTIN MICROFILAMENTS IN WHEAT ROOT-TIP CELLS', PROTOPLASMA, 147 204-206 (1988)
DOI10.1007/BF01403349Author URL
CitationsScopus - 18Web of Science - 35
1987MCCURDY DW, WILLIAMSON RE, 'AN ACTIN-RELATED PROTEIN INSIDE PEA-CHLOROPLASTS', JOURNAL OF CELL SCIENCE, 87 449-456 (1987)
Author URL
CitationsScopus - 8Web of Science - 21
1987WILLIAMSON RE, MCCURDY DW, HURLEY UA, PERKIN JL, 'ACTIN OF CHARA GIANT INTERNODAL CELLS - A SINGLE ISOFORM IN THE SUBCORTICAL FILAMENT BUNDLES AND A LARGER, IMMUNOLOGICALLY RELATED PROTEIN IN THE CHLOROPLASTS', PLANT PHYSIOLOGY, 85 268-272 (1987)
DOI10.1104/pp.85.1.268Author URL
CitationsWeb of Science - 22
1986MCCURDY DW, PRATT LH, 'IMMUNOGOLD ELECTRON-MICROSCOPY OF PHYTOCHROME IN AVENA - IDENTIFICATION OF INTRACELLULAR SITES RESPONSIBLE FOR PHYTOCHROME SEQUESTERING AND ENHANCED PELLETABILITY', JOURNAL OF CELL BIOLOGY, 103 2541-2550 (1986)
DOI10.1083/jcb.103.6.2541Author URL
CitationsWeb of Science - 59
1986MCCURDY DW, PRATT LH, 'KINETICS OF INTRACELLULAR REDISTRIBUTION OF PHYTOCHROME IN AVENA COLEOPTILES AFTER ITS PHOTOCONVERSION TO THE ACTIVE, FAR-RED-ABSORBING FORM', PLANTA, 167 330-336 (1986)
DOI10.1007/BF00391335Author URL
CitationsScopus - 9Web of Science - 25
1986WILLIAMSON RE, PERKIN JL, MCCURDY DW, CRAIG S, HURLEY UA, 'PRODUCTION AND USE OF MONOCLONAL-ANTIBODIES TO STUDY THE CYTOSKELETON AND OTHER COMPONENTS OF THE CORTICAL CYTOPLASM OF CHARA', EUROPEAN JOURNAL OF CELL BIOLOGY, 41 1-8 (1986)
Author URL
CitationsWeb of Science - 26
Show 49 more journal articles

Review (1 outputs)

YearCitationAltmetricsLink
2007Rose RJ, McCurdy DW, Sheahan MB, 'Plant mitochondria', Encyclopedia of Life Sciences (2007) [D1]
Co-authorsRay Rose

Conference (42 outputs)

YearCitationAltmetricsLink
2013Nguyen S, Zimmerman K, Arun Chinnappa KS, Collings D, McCurdy DW, 'Asymmetric distribution of AtSWEET sucrose effluxers in phloem parenchyma transfer cells of Arabidopsis veins', Poster Abstracts, Sydney (2013) [E3]
2013Wu Y, Hou J, Arun Chinnappa KS, Sheahan MB, McCurdy DW, 'Investigating roles for At3g04420 and At1g33060, two NAC-domain transcription factors, as master regulators of transfer cell development in Arabidopsis thaliana', Poster Abstracts, Sydney (2013) [E3]
2012Zhang H, McCurdy DW, Offler CE, Patrick JW, 'Ethylene and ROS regulate CA2+ channel activity to direct wall ingrowth formation of transfer cells', Poster abstracts. Combio 2012, Adelaide, SA (2012) [E3]
Co-authorsTina Offler, John Patrick
2012McCurdy DW, Hou J, Wu YB, Arun Chinnappa KS, Sheahan MB, 'Genetic regulation of phloem parenchyma transfer cell development in arabidopsis', Poster abstracts. Combio 2012, Adelaide, SA (2012) [E3]
2010Talbot MJ, Zhang H, Patrick JW, McCurdy DW, Offler CE, 'Construction of reticulate walll ingrowth labyrinths of transfer cells', International Conference on Plant Vascular Biology 2010: PVB2010, Columbus, OH (2010) [E3]
Co-authorsJohn Patrick, Tina Offler
2010Zhang H, Van Helden DF, Offler CE, McCurdy DW, Patrick JW, 'Calcium is a component of the signalling cascade leading to wall ingrowth formation in transfer cells', International Conference on Plant Vascular Biology 2010: PVB2010, Columbus, OH (2010) [E3]
Co-authorsJohn Patrick, Dirk Vanhelden, Tina Offler
2010Patrick JW, Dibley SJ, Martin A, Pugh D, McCurdy DW, 'Hexose transporters: The quiet achievers of sweeter outcomes', Plant Membrane Biology 15th International Workshop, Adelaide 2010: Programme & Abstracts, Adelaide, S.A. (2010) [E3]
Co-authorsJohn Patrick
2010Zhang H, Van Helden DF, Offler CE, McCurdy DW, Patrick JW, 'Signalling related to solute and hormone transport I', Plant Membrane Biology 15th International Workshop, Adelaide 2010: Programme & Abstracts, Adelaide, S.A. (2010) [E3]
Co-authorsTina Offler, John Patrick, Dirk Vanhelden
2010Zhang H, Van Helden DF, Offler CE, McCurdy DW, Patrick JW, 'A two-pore calcium channel is a component of the signalling cascade leading to wall ingrowth formation in transfer cells', Plant Membrane Biology 15th International Workshop, Adelaide 2010: Programme & Abstracts, Adelaide, S.A. (2010) [E3]
Co-authorsTina Offler, John Patrick, Dirk Vanhelden
2009Patrick JW, Dibley SJ, Martin A, Ruan Y-L, Offler CE, McCurdy DW, 'Fruit loading of sugars: The quest for a sweeter outcome', ComBio 2009, Christchurch, NZ (2009) [E3]
Co-authorsTina Offler, John Patrick, Yong-Ling Ruan
2009Staiger C, Sheahan MB, Khurana P, Wang X, McCurdy DW, Blanchoin L, 'Stochastic dynamics of actin filaments in the cortical array of Arabidopsis epidermal cells', Plant Biology 2009: Final Program, Honolulu, HI (2009) [E3]
2009Zhang H, Van Helden DF, McCurdy DW, Offler CE, Patrick JW, 'Calcium functions in the signalling cascade leading to wall ingrowth formation in transfer cells', ComBio 2009, Christchurch, NZ (2009) [E3]
Co-authorsJohn Patrick, Dirk Vanhelden, Tina Offler
2008Sheahan MB, McCurdy DW, Rose RJ, 'Distinct inheritance mechanisms for non-DNA containing organelles in plant cells initiating cell division', Proceedings of the Australian Society for Biochemistry and Molecular Biology, Canberra, ACT (2008) [E3]
Co-authorsRay Rose
2008Offler CE, Dibley SJ, Zhou Y, Talbot MJ, Patrick JW, McCurdy DW, 'Transfer cells play a role in seed development: How are their ingrowth walls deposited?', Proceedings of the Australian Society for Biochemistry and Molecular Biology, Canberra, ACT (2008) [E3]
Co-authorsTina Offler, John Patrick
2008Edwards J, Offler CE, Patrick JW, McCurdy DW, 'Gigantea regulates transfer cell development in arabidopsis', Proceedings of the Australian Society for Biochemistry and Molecular Biology, Canberra, ACT (2008) [E3]
Co-authorsJohn Patrick, Tina Offler
2008Andriunas FA, Offler CE, McCurdy DW, Patrick JW, 'Reactive oxygen species regulate induction of transfer cell wall ingrowths in cotyledons of Vicia faba', Proceedings of the Australian Society for Biochemistry and Molecular Biology, Canberra, ACT (2008) [E3]
Co-authorsTina Offler, John Patrick
2008Zhang H, Grant F, McCurdy DW, Patrick JW, Offler CE, 'Calcium functions in the signalling cascade leading to wall ingrowth formation in transfer cells', Proceedings of the Australian Society for Biochemistry and Molecular Biology, Canberra, ACT (2008) [E3]
Co-authorsTina Offler, John Patrick
2007Sheahan MB, McCurdy DW, Rose RJ, 'Peroxisome-mediated detoxification of mitochondrial ros in dedifferentiating plant cells', Combined Conference Abstracts - ComBio 2007 Conference, Sydney (2007) [E3]
Co-authorsRay Rose
2007Sheahan MB, Rose RJ, McCurdy DW, 'Functional differences in vegetative actins observed in dedifferentiating plant cells', Combined Conference Abstracts - ComBio 2007 Conference, Sydney (2007) [E3]
Co-authorsRay Rose
2007Offler CE, Talbot MJ, McCurdy DW, 'The role of microtubules in building reticulate and flange wall ingrowths of transfer cells', Combined Conference Abstracts - ComBio 2007 Conference, Sydney (2007) [E3]
Co-authorsTina Offler
2007Dibley SJ, McCurdy DW, Patrick JW, 'Hexose/H* symporters LEHT1 and LEHT3 are key determinants of sugar accumulation in tomato fruit', Combined Conference Abstracts - ComBio 2007 Conference, Sydney (2007) [E3]
Co-authorsJohn Patrick
2007Andriunas FA, Zhou Y, Offler CE, McCurdy DW, Patrick JW, 'Ethylene is an inductive signal for transfer cell development in cotyledons of faba bean', Combined Conference Abstracts - ComBio 2007 Conference, Sydney (2007) [E3]
Co-authorsTina Offler, John Patrick
2007Dibley SJ, Zhou Y, Talbot MJ, Offler CE, Patrick JW, McCurdy DW, 'Transcriptome profiling reveals complex and extensive transcriptional regulation accompanying transfer cell development in epidermal cells of vicia faba cotyledon', Combined Conference Abstracts - ComBio 2007 Conference, Sydney (2007) [E3]
Co-authorsJohn Patrick, Tina Offler
2007Offler CE, Talbot MJ, Dibley SJ, Vaughan KC, Wasteneys G, McCurdy DW, 'Cellulose provides the scaffolding for deposition of wall ingrowths in transfer cells', International Conference on Plant Vascular Biology 2007. Program and Abstract Book, Taipei, Taiwan (2007) [E3]
Co-authorsTina Offler
2007Dibley SJ, Zhou Y, Talbot MJ, Offler CE, Patrick JW, McCurdy DW, 'Transcriptome profiling & transfer cell development', International Conference on Plant Vascular Biology 2007. Program and Abstract Book, Taipei, Taiwan (2007) [E3]
Co-authorsTina Offler, John Patrick
2006Zhou Y, Andriunas FA, Offler CE, McCurdy DW, Patrick JW, 'The Role of Ethylene in the Induction of Transfer Cells in Cotyledons of Faba Bean', Combined Conference Abstracts, Brisbane Convention Centre, Brisbane, QLD (2006) [E3]
Co-authorsTina Offler, John Patrick
2006Sheahan MB, McCurdy DW, Rose RJ, 'Deciphering the Molecular Mechanism of Organelle Partitioning in Plant Cell Division', Conference Abstracts, Brisbane Convention Centre, Brisbane, QLD (2006) [E3]
Co-authorsRay Rose
2006Sheahan MB, Rose RJ, McCurdy DW, 'Molecular Dissection of Actin Cytoskeletal Involvement in Chloroplast Partitioning', Book of Abstracts, Adelaide Convention Centre, South Australia (2006) [E3]
Co-authorsRay Rose
2006Dibley SJ, Talbot MJ, Vaughn K, Wasteneys GO, Offler CE, McCurdy DW, 'Cellulose is required for localized wall ingrowth deposition in transfer cells of Vicia faba cotyledons', ComBio 2006 Abstracts, Brisbane, QLD (2006) [E3]
Co-authorsTina Offler
2006Sheahan MB, McCurdy DW, Rose RJ, 'An Analysis of Organelle Partitioning Before Divisionin Mesophyll Protoplasts of Medicago Truncatula with GFP-Labelled Endoplasmic Reticulum or Actin Filaments', Handbook & Abstracts, Brisbane Convention & Exhibition Centre, QLD (2006) [E3]
Co-authorsRay Rose
2004Sheahan MB, McCurdy DW, Rose RJ, 'Maintaining Mitochondrial and Mitochondrial Genome Continuity: Inheritance processes in divising tobacco Mesophyll Protoplasts', ComBio Conference Abstracts, Perth (2004) [E3]
Co-authorsRay Rose
2003Talbot MJ, Wasteneys GO, McCurdy DW, Offler CE, 'Cellulose microfibrils act as a scaffold for localized cell wall deposition in transfer cells', Australian Society of Plant Scientists 43rd Annual Meeting, Melbourne (2003) [E3]
Co-authorsTina Offler
2003Gao L, McCurdy DW, Staiger CJ, 'Biochemical and genetic analysis of the Arabidopsis fimbrin gene family', 14th International Conference on Arabidopsis Research: Abstracts, Madison, WI (2003) [E3]
2003Sheahan MB, McCurdy DW, Rose RJ, 'Organelle Inheritance in dividing protoplasts is actin dependent', 7th International Congress of Plant Molecular Biology Book of Abstracts, Barcelona, Spain (2003) [E3]
Co-authorsRay Rose
2003Sheahan MB, Rose RJ, McCurdy DW, 'Unbiased inheritance of chloroplasts, mitochondria and endoplasmic reticulum in protoplasts acquiring totipotency requires actin filaments', ComBio Combined Conference Abstracts, Melbourne (2003) [E3]
Co-authorsRay Rose
2002Talbot MJ, Wasteneys GO, Offler CE, McCurdy DW, 'Cellulose microfibril orientation in transfer cells', Australian Society of Plant Physiologists 42nd Annual Meeting, Sydney (2002) [E3]
Co-authorsTina Offler
2002Sheahan MB, McCurdy DW, Rose RJ, 'Cytoplasmic inheritance in dedifferentiating plant cells is cytoskeleton-dependent', Proceedings of the Australian Society for Biochemistry and Molecular Biology, Sydney, NSW (2002) [E3]
Co-authorsRay Rose
2001Sheahan MB, Rose RJ, McCurdy DW, 'Actin filaments are required for accurate chloroplast segregation in regenerating Nicotiana Tabacum mesophyll protoplasts', Australian Society for Biochemistry & Molecular Biology Incorp - Combio 2001, Canberra, ACT (2001) [E3]
Co-authorsRay Rose
2001Patrick JW, Gear ML, Rosche E, Offler CE, McCurdy DW, 'Spatial and temporal expression of hexose transporter genes in developing tomato fruit', Australian Society for Biochemistry & Molecular Biology Incorp - Combio 2001, Canberra ACT (2001) [E3]
Co-authorsJohn Patrick, Tina Offler
2001Talbot MJ, McCurdy DW, Offler CE, 'Wall ingrowth deposition in transfer cells', Australian Society for Biochemistry & Molecular Biology Incorp - Combio 2001, Canberra, ACT (2001) [E3]
Co-authorsTina Offler
2001Talbot MJ, McCurdy DW, Offler CE, 'Wall ingrowth deposition in transfer cells', 9th International Cell Wall Meeting, Toulouse, France (2001) [E3]
Co-authorsTina Offler
1990HARMON AC, MCCURDY DW, 'CALCIUM-DEPENDENT PROTEIN-KINASE AND ITS POSSIBLE ROLE IN THE REGULATION OF THE CYTOSKELETON', CURRENT TOPICS IN PLANT BIOCHEMISTRY AND PHYSIOLOGY 1990, VOL 9, UNIV MISSOURI COLUMBIA, COLUMBIA, MO (1990)
Author URL
CitationsWeb of Science - 7
Show 39 more conferences

Other (1 outputs)

YearCitationAltmetricsLink
2013Arun Chinnappa KS, Hou J, Wu Y, Sheahan M, McCurdy DW, 'Identification of two MYB-related transcription factors, At4g09450 and At2g38090, as putative regulators of wall ingrowth deposition in phloem parenchyma transfer cells', ( pp.1-2): ICAR (2013) [O1]
Edit

Grants and Funding

Summary

Number of grants46
Total funding$5,146,604

Click on a grant title below to expand the full details for that specific grant.


20142 grants / $425,000

Expansion and Upgrade of the Newcastle Plant Growth Facility$230,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project TeamAssociate Professor David McCurdy, Professor Christopher Grof, Doctor Andy Eamens, Associate Professor Yong-Ling Ruan, Conjoint Professor Christina Offler
SchemeLinkage Infrastructure Equipment & Facilities (LIEF)
RoleLead
Funding Start2014
Funding Finish2014
GNoG1300636
Type Of FundingScheme excluded from IGS
CategoryEXCL
UONY

Expansion and Upgrade of the Newcastle Plant Growth Facility$195,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy, Professor Christopher Grof, Doctor Andy Eamens, Associate Professor Yong-Ling Ruan, Conjoint Professor Christina Offler
SchemeEquipment Grant
RoleLead
Funding Start2014
Funding Finish2014
GNoG1300231
Type Of FundingInternal
CategoryINTE
UONY

20132 grants / $161,670

Refurbishment of the Newcastle Plant Growth Facility$160,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy, Professor Christopher Grof, Associate Professor Yong-Ling Ruan, Conjoint Professor Ray Rose, Conjoint Professor Christina Offler
SchemeEquipment Grant
RoleLead
Funding Start2013
Funding Finish2013
GNoG1200380
Type Of FundingInternal
CategoryINTE
UONY

Faculty PVC Conference Assistance Grant 2013$1,670

Funding body: University of Newcastle - Faculty of Science & IT

Funding bodyUniversity of Newcastle - Faculty of Science & IT
Project TeamAssociate Professor David McCurdy
SchemePVC Conference Assistance Grant
RoleLead
Funding Start2013
Funding Finish2013
GNoG1401171
Type Of FundingInternal
CategoryINTE
UONY

20123 grants / $39,000

2011 Emerging Research Leaders Program$15,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy
SchemeEmerging Research Leaders Program
RoleLead
Funding Start2012
Funding Finish2012
GNoG1200646
Type Of FundingInternal
CategoryINTE
UONY

Using the vte2 mutant to discover transciptional regulators of transfer cell development in the model higher plant Arabidopsis thaliana$14,000

Funding body: University of Newcastle - Faculty of Science & IT

Funding bodyUniversity of Newcastle - Faculty of Science & IT
Project TeamAssociate Professor David McCurdy
SchemeStrategic Small Grant
RoleLead
Funding Start2012
Funding Finish2012
GNoG1401101
Type Of FundingInternal
CategoryINTE
UONY

Immunolocalisation of AtSWEET11, the long sought-after sucrose efflux transporter responsible for phloem loading in Arabidopsis thaliana$10,000

Funding body: University of Newcastle - Faculty of Science & IT

Funding bodyUniversity of Newcastle - Faculty of Science & IT
Project TeamAssociate Professor David McCurdy
SchemeStrategic Initiative Research Fund (SIRF)
RoleLead
Funding Start2012
Funding Finish2012
GNoG1401026
Type Of FundingInternal
CategoryINTE
UONY

20112 grants / $794,000

Specialised Greenhouse Space for New Initiatives $500,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project TeamProfessor Christopher Grof, Associate Professor Yong-Ling Ruan, Associate Professor David McCurdy, Emeritus Professor John Patrick, Conjoint Professor Ray Rose
SchemeLinkage Infrastructure Equipment & Facilities (LIEF)
RoleInvestigator
Funding Start2011
Funding Finish2011
GNoG1000631
Type Of FundingScheme excluded from IGS
CategoryEXCL
UONY

Wall Ingrowth Formation in Plant Transfer Cells - Discovering Regulatory Transcription Factor Cascades$294,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project TeamAssociate Professor David McCurdy
SchemeDiscovery Projects
RoleLead
Funding Start2011
Funding Finish2011
GNoG1000128
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

20104 grants / $577,000

ARE - Researcher of the Year 2010$10,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy
SchemeAward for Research Excellence
RoleLead
Funding Start2010
Funding Finish2010
GNoG1001075
Type Of FundingInternal
CategoryINTE
UONY

Faculty of Science and IT - Award for Research Excellence$2,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy
SchemeAward for Research Excellence
RoleLead
Funding Start2010
Funding Finish2010
GNoG1001019
Type Of FundingInternal
CategoryINTE
UONY

20093 grants / $995,000

Confocal Laser Scanning Microscopy for Live Cell Imaging$275,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project TeamConjoint Professor Keith Jones, Professor Eileen McLaughlin, Laureate Professor John Aitken, Conjoint Professor Ray Rose, Emeritus Professor John Patrick, Conjoint Professor Christina Offler, Associate Professor David McCurdy, Emeritus Professor Leonie Ashman, Professor Gordon Burns, Professor Dirk Van Helden, Doctor Nikki Verrills, Associate Professor Brett Nixon, Doctor Shaun Roman, Associate Professor Yong-Ling Ruan, Doctor Rick Thorne, Professor Mike Calford
SchemeLinkage Infrastructure Equipment & Facilities (LIEF)
RoleInvestigator
Funding Start2009
Funding Finish2009
GNoG0189038
Type Of FundingScheme excluded from IGS
CategoryEXCL
UONY

20081 grants / $1,110

ComBio 2008 (Combined Annual Meeting of ASPS, ASBMB, ANZSCDB), National Convention Centre Canberra, 21/9/2008 - 25/9/2008$1,110

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy
SchemeTravel Grant
RoleLead
Funding Start2008
Funding Finish2008
GNoG0189550
Type Of FundingInternal
CategoryINTE
UONY

20072 grants / $10,773

Functional characterisation of membrane transporters responsible for sugar accumulation in tomato fruit$8,273

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy
SchemePilot Grant
RoleLead
Funding Start2007
Funding Finish2007
GNoG0187849
Type Of FundingInternal
CategoryINTE
UONY

International Conference on Plant Vascular Biology 2007, Academic Sinica Taipei, Taiwan, 7/5/2007 - 11/5/2007$2,500

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy
SchemeTravel Grant
RoleLead
Funding Start2007
Funding Finish2007
GNoG0187777
Type Of FundingInternal
CategoryINTE
UONY

20062 grants / $323,500

Induction of Plant Transfer Cells - Discovering Regulatory Networks$322,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project TeamEmeritus Professor John Patrick, Associate Professor David McCurdy, Conjoint Professor Christina Offler
SchemeDiscovery Projects
RoleInvestigator
Funding Start2006
Funding Finish2006
GNoG0185249
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

8th International Congress of Plant Molecular Biology, Adelaide Convention Centre, 20 - 25/8/2006$1,500

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy
SchemeTravel Grant
RoleLead
Funding Start2006
Funding Finish2006
GNoG0186879
Type Of FundingInternal
CategoryINTE
UONY

20052 grants / $507,189

Plant Transfer Cells - Discovering the Mechanisms of Wall Ingrowth Formation$300,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project TeamConjoint Professor Christina Offler, Associate Professor David McCurdy
SchemeDiscovery Projects
RoleInvestigator
Funding Start2005
Funding Finish2005
GNoG0184327
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

20042 grants / $339,004

Upgrade and expansion of Newcastle Plant Growth Facility$329,504

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project TeamEmeritus Professor John Patrick, Conjoint Professor Ray Rose, Conjoint Professor Christina Offler, Associate Professor David McCurdy, Mr Michael Cole, Doctor Geoffrey MacFarlane, Professor John Rodger
SchemeLinkage Infrastructure Equipment & Facilities (LIEF)
RoleInvestigator
Funding Start2004
Funding Finish2004
GNoG0183029
Type Of FundingScheme excluded from IGS
CategoryEXCL
UONY

Mechanisms of wall ingrowth deposition intransfer cells.$9,500

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamConjoint Professor Christina Offler, Associate Professor David McCurdy
SchemeProject Grant
RoleInvestigator
Funding Start2004
Funding Finish2004
GNoG0183471
Type Of FundingInternal
CategoryINTE
UONY

20031 grants / $873

ComBio 2003 28/0903 to 2/10/03$873

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy
SchemeTravel Grant
RoleLead
Funding Start2003
Funding Finish2003
GNoG0183737
Type Of FundingInternal
CategoryINTE
UONY

20022 grants / $7,425

Molecular and cellular analysis of cell division induction in totipotent plant cells$6,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy, Conjoint Professor Ray Rose
SchemeProject Grant
RoleLead
Funding Start2002
Funding Finish2002
GNoG0181467
Type Of FundingInternal
CategoryINTE
UONY

Gordon Research Conference on the Plant and Fungal Cytoskeleton New Hampshire, 11-16 August 2002$1,425

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy
SchemeTravel Grant
RoleLead
Funding Start2002
Funding Finish2002
GNoG0181995
Type Of FundingInternal
CategoryINTE
UONY

20012 grants / $19,000

The role of the cytoskeleton in regulating development of plant transfer cells.$12,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamConjoint Professor Christina Offler, Professor V Franceschi, Associate Professor David McCurdy
SchemeProject Grant
RoleInvestigator
Funding Start2001
Funding Finish2001
GNoG0180129
Type Of FundingInternal
CategoryINTE
UONY

Analysis of the biochemical and live cell properties of the fimbrin family of actin-binding proteins in Arabidopsis thaliana.$7,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy, Assoc. Prof C Staiger
SchemeProject Grant
RoleLead
Funding Start2001
Funding Finish2001
GNoG0180131
Type Of FundingInternal
CategoryINTE
UONY

20005 grants / $122,640

Genetic engineering of enhanced sweetness and flavour in tomato fruit$78,240

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project TeamEmeritus Professor John Patrick, Associate Professor David McCurdy
SchemeStrategic Partnerships with Industry - Research & Training Scheme (SPIRT)
RoleInvestigator
Funding Start2000
Funding Finish2000
GNoG0178642
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

Genetic engineering of enhanced sweetness and flavour in tomato fruit$30,000

Funding body: Yates Vegetable Seeds Pty Ltd

Funding bodyYates Vegetable Seeds Pty Ltd
Project TeamEmeritus Professor John Patrick, Associate Professor David McCurdy
SchemeSPIRT Partner funding
RoleInvestigator
Funding Start2000
Funding Finish2000
GNoG0181250
Type Of FundingContract - Aust Non Government
Category3AFC
UONY

The Role of the Cytoskeleton During Differentialtion of Transfer Cells.$7,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamConjoint Professor Christina Offler, Associate Professor David McCurdy
SchemeProject Grant
RoleInvestigator
Funding Start2000
Funding Finish2000
GNoG0178974
Type Of FundingInternal
CategoryINTE
UONY

Functional Characterisation of the Fimbrin-Like Gene Family in Arabidopsis Thaliana.$5,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy
SchemeProject Grant
RoleLead
Funding Start2000
Funding Finish2000
GNoG0178975
Type Of FundingInternal
CategoryINTE
UONY

Gordon Research Conference.$2,400

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy
SchemeTravel Grant
RoleLead
Funding Start2000
Funding Finish2000
GNoG0180304
Type Of FundingInternal
CategoryINTE
UONY

19992 grants / $210,107

Confocal Laser Scanning Microscope Facility.$203,107

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project TeamLaureate Professor John Aitken, Emeritus Professor John Patrick, Conjoint Professor Christina Offler, Associate Professor David McCurdy, Conjoint Professor Ray Rose, Doctor Tim Roberts, Conjoint Associate Professor Russell Jones, Doctor John Clulow, Emeritus Professor John Rostas, Professor Alistair Sim, Professor Gordon Burns, Conjoint Professor Loris Chahl, DR DAVID KAY
SchemeLarge Equipment Grant
RoleInvestigator
Funding Start1999
Funding Finish1999
GNoG0177945
Type Of FundingScheme excluded from IGS
CategoryEXCL
UONY

The role of the cell cytoskeleton during differentiation of transfer cells$7,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamConjoint Professor Christina Offler, Associate Professor David McCurdy
SchemeProject Grant
RoleInvestigator
Funding Start1999
Funding Finish1999
GNoG0178190
Type Of FundingInternal
CategoryINTE
UONY

19983 grants / $254,866

Specialised Environmental Space for Newcastle Plant Growth$250,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project TeamEmeritus Professor John Patrick, Conjoint Professor Ray Rose, Conjoint Professor Christina Offler, Associate Professor David McCurdy, Mr Michael Cole
SchemeLarge Equipment Grant
RoleInvestigator
Funding Start1998
Funding Finish1998
GNoG0177584
Type Of FundingScheme excluded from IGS
CategoryEXCL
UONY

Functional characterization of novel actin filament-bundling proteins and their genes identified in the higher plant Arabidopsis thaliana.$3,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy
SchemeProject Grant
RoleLead
Funding Start1998
Funding Finish1998
GNoG0177294
Type Of FundingInternal
CategoryINTE
UONY

Gordon Research Conference: The Plant and Fungal Cytoskeleton, USA 9-13 August 1998$1,866

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy
SchemeTravel Grant
RoleLead
Funding Start1998
Funding Finish1998
GNoG0180348
Type Of FundingInternal
CategoryINTE
UONY

19961 grants / $180,000

Molecular biology of plasma membrane hexose porters in developing tomato fruit$180,000

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project TeamEmeritus Professor John Patrick, Associate Professor David McCurdy
SchemeLarge Grant
RoleInvestigator
Funding Start1996
Funding Finish1996
GNoG0175260
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

19953 grants / $33,683

Laboratory Upgrade$17,600

Funding body: Department of Education, Training & Youth Affairs

Funding bodyDepartment of Education, Training & Youth Affairs
Project TeamEmeritus Professor John Patrick, Conjoint Professor Ray Rose, Associate Professor David McCurdy, Conjoint Professor Christina Offler, Mr Michael Cole
SchemeResearch Infrastructure Block Grant (RIBG)
RoleInvestigator
Funding Start1995
Funding Finish1995
GNoG0175592
Type Of FundingScheme excluded from IGS
CategoryEXCL
UONY

Molecular cloning of myosin light chain genes in higher plants$14,000

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy
SchemeProject Grant
RoleLead
Funding Start1995
Funding Finish1995
GNoG0174848
Type Of FundingInternal
CategoryINTE
UONY

Gordon Conference (Plant & Fungal Cytoskeleton)(New Hampshire) and ASPP Annual Meeting (North Carolina)$2,083

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy
SchemeTravel Grant
RoleLead
Funding Start1995
Funding Finish1995
GNoG0175536
Type Of FundingInternal
CategoryINTE
UONY

19941 grants / $135,264

94,95,96 GRANT. Molecular control of plant cell morphogenesis: actin-binding proteins and their genes.$135,264

Funding body: ARC (Australian Research Council)

Funding bodyARC (Australian Research Council)
Project TeamAssociate Professor David McCurdy
SchemeLarge Grant
RoleLead
Funding Start1994
Funding Finish1994
GNoG0172923
Type Of FundingAust Competitive - Commonwealth
Category1CS
UONY

19931 grants / $9,500

Molecular Control of Plant Cell Morphogenesis: actin-binding Proteins and their genes.$9,500

Funding body: University of Newcastle

Funding bodyUniversity of Newcastle
Project TeamAssociate Professor David McCurdy
SchemeNew Staff Grant
RoleLead
Funding Start1993
Funding Finish1993
GNoG0172983
Type Of FundingInternal
CategoryINTE
UONY
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Research Supervision

Current Supervision

CommencedResearch Title / Program / Supervisor Type
2013Investigating Molecular Regulation of Transfer Cell Development in the Model Flowering Plant Arabidopsis Thaliana
Biological Sciences, Faculty of Science and Information Technology
Principal Supervisor
2013Investigating a Role for NAC Transcription Factors as Master Regulators of Transfer Cell Development in Arabidopsis Thaliana
Biological Sciences, Faculty of Science and Information Technology
Principal Supervisor
2012Investigating Signals Regulating Transfer Cell Development in the Model Flowering Plant Arabidopsis thaliana
Biological Sciences, Faculty of Science and Information Technology
Principal Supervisor
2011Discovering Transcription Factors Regulating Wall Ingrowth Formation in Plant Transfer Cells
Biological Sciences, Faculty of Science and Information Technology
Principal Supervisor

Past Supervision

YearResearch Title / Program / Supervisor Type
2013Discovering Roles of Calcium and Cortical Microtubules in Directing Ingrowth Wall Formation During Trans-Differentiation of Epidermal Cells to a Transfer Cell Morphology
Biological Sciences, Faculty of Science and Information Technology
Co-Supervisor
2011Transfer Cell Trans-differentiation in Vicia Faba Cotyledons: Regulatory Roles of Ethylene, Glucose and Reactive Oxygen Species
Biological Sciences, Faculty of Science and Information Technology
Co-Supervisor
2007Towards an Understanding of Organelle Inheritance Processes During Plant Cell Dedifferentiation
Biological Sciences, Faculty of Science and Information Technology
Co-Supervisor
2006Investigating mechanisms of localized wall ingrowth deposition in transfer cells
Biological Sciences, Faculty of Science and Information Technology
Co-Supervisor
2005The Role of Hexose/H+ Symporters in Sugar Accumulation by Fruit of Tomato (Lycopersicon Esculentum)
Biological Sciences, Faculty of Science and Information Technology
Principal Supervisor
2001Molecular biology of hexose transporters in tomato fruit
Biol Sc Not Elsewhere Classifd, University of Newcastle
Co-Supervisor
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Associate Professor David McCurdy

Position

Associate Professor
School of Environmental and Life Sciences
Faculty of Science and Information Technology

Focus area

Biological Sciences

Contact Details

Emaildavid.mccurdy@newcastle.edu.au
Phone(02) 4921 5879
Fax(02) 4921 5472

Office

RoomBG13
BuildingBiological Sciences
LocationCallaghan
University Drive
Callaghan, NSW 2308
Australia
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