Staff Profile
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Career Summary
Biography
After obtaining an Australia postgraduate Award, I did my PhD at Monash University, Department of Biochemistry and Cell Biology under the supervision of Dr. Alfons Lawen. Following a successful time, I was invited to the join the group at the University of Newcastle under Prof. John Aitken, which was a continuation of my PhD theme in the identifying plasma membrane redox systems. Within two years, I decided to set-up and establish a proteomics platform at the University of Newcastle and have since been successful in establishing 4 mass spectrometers in the Advanced mass spectrometry facility. In 2005 I was awarded the university of Newcastle Fellowship (rank #1 from 96 applications) which allowed 5 years of full time research. In 2011 I was awarded the NHMRC career development fellowship (level 2) from the NHMRC.
I have been successful on 3 NHMRC DP grants, 1 ARC project grant and 3 ARC LIEF grants.
Qualifications
- PhD, Monash University, 03/04/2003
Research
Research keywords
- Fertilization
- Phosphorylation
- Spermatozoa
Research expertise
Proteomics and phospho-proteomics comparisons using label-free mass spectrometry
Fields of Research
| Code | Description | Percentage |
|---|---|---|
| 060111 | Signal Transduction | 40 |
| 060100 | Biochemistry And Cell Biology | 30 |
| 111400 | Paediatrics And Reproductive Medicine | 30 |
Appointments
| NHMRC Career development Fellow NHMRC (Australia) | 01/02/2012 |
Collaboration
Nuch Tanphaichitr, Senior Scientist, Ottawa Hospital Research Institute, and Professor in Obstetrics and Gynecology, and Biochemistry/Microbiology/Immunology, University of Ottawa
Harvey Florman, University of Massachusetts
Melissa Junganickel, University of Massachusetts
Gibbes Johnson, Acting Deputy Director, Division of Therapeutic Proteins CDER, FDA, Bethesda University
John Aitken, University of Newcastle
Neil Sprat, University of Newcastle
Tony Velkov, University of Newcastle
Brett Nixon, University of Newcastle
Administrative
Administrative expertise
Grants, animal ethics, Health and Safety
Teaching
Teaching keywords
- Biol 3000
Teaching expertise
6 lectures to Biol 3020 on reproductive physiology
Edit
- Indicates that the researcher may be seeking students for this project.Triple Quadrupole Mass Spectrometer with nano-infusion for targeted protein quantification$300,000
NucleoCounter SP100$14,000
Understanding sperm motility for infertility and contraceptive purposes$432,568
BMG SPECTROstar Nano$15,000
PULSE Early Career Researcher$10,000
Chemical principles underpinning a spermostatic-microbiostatic agent capable of preventing pregnancy and the spread of sexually transmitted disease$735,000
Understanding the Molecular Basis of Epididymal Maturation: How Does the Epididymis Modify Spermatozoa, Allowing them to Recognise the Egg?$565,222
An Advanced Mass Spectrometer for Applications in Phospho-Proteomics, Glycomics and Top-Down Sequencing of Proteins$250,000
3D Ion Trap Mass Spectrometer with ETD for Top Down Proteomics Applications$170,000
An Advanced Mass Spectrometer for Applications in Phospho-Proteomics, Glycomics and Top-Down Sequencing of Proteins$15,000
An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$500,000
An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$280,000
Waters, Ultra high performance liquid chromatography system (nano-Aquity)
$30,000
The design of novel, affinity-based technology to specifically isolate phosphotyrosine-containing pedtides$25,000
2009 FSIT Award for Research Excellence$2,000
An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000
Identification and characterisation of phosphorylation events taking place during human sperm capacitation$269,250
China-Australia therapeutic hypothermia in stroke (CATHS) research program: identification of diagnostic molecular markers and therapeutic targets involved in re-warming related brain injury$230,275
Assessing the significance of the sperm thioredoxins as contraceptive targets for the male$148,096
An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000
PULSE Education Prize$4,000
2007 Research Fellowship - PRCRS$509,053
AMPPAII Proposal for completion of the Sptrx KO mice study$198,741
2007 Research Fellowship Project Grant$15,000
Grants and Funding
Summary
| Number of grants | 24 |
|---|---|
| Total funding | $5,263,205 |
For project grants received where the lead institution is other than the University of Newcastle, details are shown in italics.
Click on a grant title below to expand the full details for that specific grant.
2013 (2 grants)
Triple Quadrupole Mass Spectrometer with nano-infusion for targeted protein quantification$300,000
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Doctor Mark Baker, Laureate Professor John Aitken, Professor Bogdan Dlugogorski, Professor Hubert Hondermarck | ||
| Scheme | Role | |
| Equipment Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $300,000 | 2013 | 2013 |
| GNo:G1200137 | ||
NucleoCounter SP100$14,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Laureate Professor John Aitken, Associate Professor Brett Nixon, Doctor Shaun Roman, Doctor Mark Baker, Doctor Geoffry De Iuliis, Doctor Lisa Mitchell, Doctor Matthew Jobling, Ms Zamira Gibb, Mr Nenad Naumovski | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $14,000 | 2013 | 2013 |
| GNo:G1201175 | ||
2012 (3 grants)
Understanding sperm motility for infertility and contraceptive purposes$432,568
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Doctor Mark Baker | ||
| Scheme | Role | |
| Career Development Fellowships | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $432,568 | 2012 | 2015 |
| GNo:G1100192 | ||
BMG SPECTROstar Nano$15,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Laureate Professor John Aitken, Professor Eileen McLaughlin, Ms Belinda Nixon, Doctor Shaun Roman, Doctor Mark Baker, Doctor Geoffry De Iuliis, Doctor Lisa Mitchell, Doctor Matthew Jobling | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $15,000 | 2012 | 2012 |
| GNo:G1100971 | ||
PULSE Early Career Researcher$10,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Doctor Mark Baker | ||
| Scheme | Role | |
| PULSE Early Career Researcher Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $10,000 | 2012 | 2013 |
| GNo:G1200578 | ||
2011 (5 grants)
Chemical principles underpinning a spermostatic-microbiostatic agent capable of preventing pregnancy and the spread of sexually transmitted disease$735,000
Funding Body: ARC (Australian Research Council)
| Project Team | ||
|---|---|---|
| Laureate Professor John Aitken, Doctor Mark Baker, Professor Kenneth Beagley, Professor Adam McCluskey | ||
| Scheme | Role | |
| Discovery Projects | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $735,000 | 2011 | 2013 |
| GNo:G1000173 | ||
Understanding the Molecular Basis of Epididymal Maturation: How Does the Epididymis Modify Spermatozoa, Allowing them to Recognise the Egg?$565,222
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Doctor Mark Baker | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $565,222 | 2011 | 2013 |
| GNo:G1000306 | ||
An Advanced Mass Spectrometer for Applications in Phospho-Proteomics, Glycomics and Top-Down Sequencing of Proteins$250,000
Funding Body: ARC (Australian Research Council)
| Project Team | ||
|---|---|---|
| Doctor Mark Baker, Laureate Professor John Aitken, Professor Roger Smith, Conjoint Professor Keith Jones, Conjoint Professor Ray Rose, Professor Lois Salamonsen | ||
| Scheme | Role | |
| Linkage Infrastructure Equipment & Facilities (LIEF) | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $250,000 | 2011 | 2011 |
| GNo:G1000632 | ||
3D Ion Trap Mass Spectrometer with ETD for Top Down Proteomics Applications$170,000
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Doctor Mark Baker, Laureate Professor John Aitken | ||
| Scheme | Role | |
| Equipment Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $170,000 | 2011 | 2011 |
| GNo:G1000470 | ||
An Advanced Mass Spectrometer for Applications in Phospho-Proteomics, Glycomics and Top-Down Sequencing of Proteins$15,000
Funding Body: Prince Henry's Institute of Medical Research
| Project Team | ||
|---|---|---|
| Doctor Mark Baker, Laureate Professor John Aitken, Professor Roger Smith, Conjoint Professor Keith Jones, Conjoint Professor Ray Rose, Professor Lois Salamonsen | ||
| Scheme | Role | |
| Linkage Infrastructure Equipment & Facilities (LIEF) Partner funding | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $15,000 | 2011 | 2011 |
| GNo:G1100844 | ||
2010 (5 grants)
An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$500,000
Funding Body: ARC (Australian Research Council)
| Project Team | ||
|---|---|---|
| Professor Adam McCluskey, Laureate Professor John Aitken, Professor Paul Dastoor, Professor Phillip Robinson, Professor Eileen McLaughlin, Emeritus Professor Geoffrey Lawrance, Professor Marcel Maeder, Professor Hugh Dunstan, Doctor Shaun Roman, Associate Professor Rob Atkin, Doctor Clovia Holdsworth, Doctor Mark Baker, Doctor Nikki Verrills, Professor Gottfried Otting, Associate Professor Brett Nixon, Doctor Xiaojing Zhou, Ms Megan Chircop, Doctor Warwick Belcher | ||
| Scheme | Role | |
| Linkage Infrastructure Equipment & Facilities (LIEF) | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $500,000 | 2010 | 2010 |
| GNo:G0190402 | ||
An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$280,000
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Professor Adam McCluskey, Laureate Professor John Aitken, Professor Paul Dastoor, Professor Phillip Robinson, Professor Eileen McLaughlin, Emeritus Professor Geoffrey Lawrance, Professor Marcel Maeder, Professor Hugh Dunstan, Doctor Shaun Roman, Associate Professor Rob Atkin, Doctor Clovia Holdsworth, Doctor Mark Baker, Doctor Nikki Verrills, Professor Gottfried Otting, Associate Professor Brett Nixon, Doctor Xiaojing Zhou, Ms Megan Chircop, Doctor Warwick Belcher | ||
| Scheme | Role | |
| Equipment Grant | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $280,000 | 2010 | 2010 |
| GNo:G1000873 | ||
Waters, Ultra high performance liquid chromatography system (nano-Aquity)
$30,000
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Doctor Mark Baker, Laureate Professor John Aitken, Professor Adam McCluskey, Associate Professor Brett Nixon, Professor John Rostas, Professor Eileen McLaughlin | ||
| Scheme | Role | |
| Equipment Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $30,000 | 2010 | 2010 |
| GNo:G1000051 | ||
The design of novel, affinity-based technology to specifically isolate phosphotyrosine-containing pedtides$25,000
Funding Body: Hunter Children`s Research Foundation
| Project Team | ||
|---|---|---|
| Doctor Mark Baker, Professor Adam McCluskey | ||
| Scheme | Role | |
| Research Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $25,000 | 2010 | 2010 |
| GNo:G0900191 | ||
2009 FSIT Award for Research Excellence$2,000
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Doctor Mark Baker | ||
| Scheme | Role | |
| Award for Research Excellence | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $2,000 | 2010 | 2010 |
| GNo:G1000404 | ||
2009 (5 grants)
An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000
Funding Body: ARC (Australian Research Council)
| Project Team | ||
|---|---|---|
| Laureate Professor John Aitken, Professor Adam McCluskey, Doctor Mark Baker, Doctor Nikki Verrills, Professor Marcel Maeder, Doctor Xiaojing Zhou, Professor Eileen McLaughlin, Associate Professor Brett Nixon, Doctor Shaun Roman, Conjoint Professor Ray Rose, Professor Hugh Dunstan, Professor Christopher Grof, Professor Roger Smith, Conjoint Professor Peter Gibson, Conjoint Professor Alison Jones, Professor Mike Calford, Conjoint Professor Keith Jones, Doctor Rick Thorne, Emeritus Professor Peter Dunkley, Professor Paul Foster, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Associate Professor Phillip Dickson, Professor John Rostas, Professor Rodney Scott, Associate Professor Paul Tooney, Professor Phil Hansbro, Professor Pablo Moscato, Professor Paul Dastoor, Professor Peter Lewis | ||
| Scheme | Role | |
| Linkage Infrastructure Equipment & Facilities (LIEF) | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $495,000 | 2009 | 2009 |
| GNo:G0189122 | ||
Identification and characterisation of phosphorylation events taking place during human sperm capacitation$269,250
Funding Body: NHMRC (National Health & Medical Research Council)
| Project Team | ||
|---|---|---|
| Doctor Mark Baker | ||
| Scheme | Role | |
| Project Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $269,250 | 2009 | 2011 |
| GNo:G0188834 | ||
China-Australia therapeutic hypothermia in stroke (CATHS) research program: identification of diagnostic molecular markers and therapeutic targets involved in re-warming related brain injury$230,275
Funding Body: NSW Office for Science & Medical Research
| Project Team | ||
|---|---|---|
| Conjoint Professor Chris Levi, Doctor Mark Baker, Doctor Neil Spratt, Professor John Rostas | ||
| Scheme | Role | |
| China-NSW Collaborative Research Program | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $230,275 | 2009 | 2009 |
| GNo:G0190392 | ||
Assessing the significance of the sperm thioredoxins as contraceptive targets for the male$148,096
Funding Body: Contraceptive Research and Development Program
| Project Team | ||
|---|---|---|
| Laureate Professor John Aitken, Doctor Mark Baker | ||
| Scheme | Role | |
| Development of New or Improved Contraceptive Products | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $148,096 | 2009 | 2009 |
| GNo:G0189339 | ||
An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000
Funding Body: ARC (Australian Research Council)
| Project Team | ||
|---|---|---|
| Laureate Professor John Aitken, Professor Adam McCluskey, Doctor Mark Baker, Doctor Nikki Verrills, Professor Marcel Maeder, Doctor Xiaojing Zhou, Professor Eileen McLaughlin, Associate Professor Brett Nixon, Doctor Shaun Roman, Conjoint Professor Ray Rose, Professor Hugh Dunstan, Professor Christopher Grof, Professor Roger Smith, Conjoint Professor Peter Gibson, Conjoint Professor Alison Jones, Professor Mike Calford, Conjoint Professor Keith Jones, Doctor Rick Thorne, Emeritus Professor Peter Dunkley, Professor Paul Foster, Conjoint Professor Leonie Ashman, Professor Gordon Burns, Associate Professor Phillip Dickson, Professor John Rostas, Professor Rodney Scott, Associate Professor Paul Tooney, Professor Phil Hansbro, Professor Pablo Moscato, Professor Paul Dastoor, Professor Peter Lewis | ||
| Scheme | Role | |
| Linkage Infrastructure Equipment & Facilities (LIEF) Partner funding | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $50,000 | 2009 | 2009 |
| GNo:G0189948 | ||
2008 (1 grants)
PULSE Education Prize$4,000
Funding Body: Hunter Medical Research Institute
| Project Team | ||
|---|---|---|
| Doctor Mark Baker | ||
| Scheme | Role | |
| PULSE Education Prize | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $4,000 | 2008 | 2008 |
| GNo:G0188535 | ||
2007 (3 grants)
2007 Research Fellowship - PRCRS$509,053
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Doctor Mark Baker | ||
| Scheme | Role | |
| Research Fellowship | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $509,053 | 2007 | 2012 |
| GNo:G0187158 | ||
AMPPAII Proposal for completion of the Sptrx KO mice study$198,741
Funding Body: Schering AG
| Project Team | ||
|---|---|---|
| Laureate Professor John Aitken, Doctor Mark Baker | ||
| Scheme | Role | |
| Research Networks | Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $198,741 | 2007 | 2007 |
| GNo:G0188468 | ||
2007 Research Fellowship Project Grant$15,000
Funding Body: University of Newcastle
| Project Team | ||
|---|---|---|
| Doctor Mark Baker | ||
| Scheme | Role | |
| Fellowship Grant | Chief Investigator | |
| Total Amount | Funding Start | Funding Finish |
| $15,000 | 2007 | 2007 |
| GNo:G0188117 | ||
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Research Supervision
| Number of current supervisions | 1 |
|---|---|
| Total current UoN PhD EFTSL | 0.4 |
For supervisions undertaken at an institution other that the University of Newcastle, details are shown in italics, and the institution name is listed below the program name.
Current Supervision
| Commenced | Proposed Completion | Program | Supervisor Type | Research Title |
|---|---|---|---|---|
| 2013 | 2017 | PhD (Biological Sciences) | Co-Supervisor | Analysis of Metabolic Mechanisms Controlling Glucose Metabolism in Mammalian Spermatozoa |
Edit
Dr Mark Baker
| Work Phone | (02) 4921 7880 |
|---|---|
| Fax | (02) 4921 6308 |
| Mark.Baker@newcastle.edu.au | |
| Position | Research Fellow School of Environmental and Life Sciences Faculty of Science and Information Technology |
| Focus Area | Biological Sciences |
| Office | LS4-42, Life Sciences, Callaghan University Drive Callaghan NSW 2308 Australia |
| URL: | www.newcastle.edu.au/profile/mark-baker |
