Profile Image

Staff Profile

Edit

Career Summary

Biography

After obtaining an Australia postgraduate Award, I did my PhD at Monash University, Department of Biochemistry and Cell Biology under the supervision of Dr. Alfons Lawen. Following a successful time, I was invited to the join the group at the University of Newcastle under Prof. John Aitken, which was a continuation of my PhD theme in the identifying plasma membrane redox systems. Within two years, I decided to set-up and establish a proteomics platform at the University of Newcastle and have since been successful in establishing 4 mass spectrometers in the Advanced mass spectrometry facility. In 2005 I was awarded the university of Newcastle Fellowship (rank #1 from 96 applications) which allowed 5 years of full time research. In 2011 I was awarded the NHMRC career development fellowship (level 2) from the NHMRC.

I have been successful on 3 NHMRC DP grants, 1 ARC project grant and 3 ARC LIEF grants.

Qualifications

  • PhD, Monash University, 03/04/2003

Research

Research keywords

  • Fertilization
  • Phosphorylation
  • Spermatozoa

Research expertise

Proteomics and phospho-proteomics comparisons using label-free mass spectrometry

Fields of Research

CodeDescriptionPercentage
060111Signal Transduction40
060100Biochemistry And Cell Biology30
111400Paediatrics And Reproductive Medicine30

Appointments

NHMRC Career development Fellow
NHMRC (Australia)
01/02/2012

Collaboration

Nuch Tanphaichitr, Senior Scientist, Ottawa Hospital Research Institute, and Professor in Obstetrics and Gynecology, and Biochemistry/Microbiology/Immunology, University of Ottawa

Harvey Florman, University of Massachusetts

Melissa Junganickel, University of Massachusetts

Gibbes Johnson, Acting Deputy Director, Division of Therapeutic Proteins CDER, FDA, Bethesda University

John Aitken, University of Newcastle

Neil Sprat, University of Newcastle

Tony Velkov, University of Newcastle

Brett Nixon, University of Newcastle

Administrative

Administrative expertise

Grants, animal ethics, Health and Safety

Teaching

Teaching keywords

  • Biol 3000

Teaching expertise

6 lectures to Biol 3020 on reproductive physiology

Edit

Highlighted Publications

For publications that are currently unpublished or in-press, details are shown in italics.

YearCitationAltmetricsLink
2009Baker MA, Hetherington L, Curry BJ, Aitken RJ, 'Phosphorylation and consequent stimulation of the tyrosine kinase c-Abl by PKA in mouse spermatozoa: Its implications during capacitation', Developmental Biology, 333 57-66 (2009) [C1]
2011Baker MA, Smith ND, Hetherington L, Pelzing M, Condina MR, Aitken RJ, 'Use of titanium dioxide to find phosphopeptide and total protein changes during epididymal sperm maturation', Journal of Proteome Research, 10 1004-1017 (2011) [C1]
2010Baker MA, Smith ND, Hetherington L, Taubman K, Graham ME, Robinson PJ, Aitken RJ, 'Label-free quantitation of phosphopeptide changes during rat sperm capacitation', Journal of Proteome Research, 9 718-729 (2010) [C1]
2008Aitken RJ, Baker MA, Doncel GF, Matzuk MM, Mauck CK, Harper MJK, 'As the world grows: Contraception in the 21st century', Journal of Clinical Investigation, 118 1330-1343 (2008) [C1]

Publications

For publications that are currently unpublished or in-press, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Chapter (5 outputs)

YearCitationAltmetricsLink
2013Baker MA, Aitken RJ, 'Mass Spectrometry, Proteomics, and the Study of Sperm Cell Biology', Human Gametes and Preimplantation Embryos (2013)
2013Baker MA, 'Phosphoproteomic analysis of peptides', 271-277 (2013)
2012Aitken RJ, De Iuliis GN, Baker MA, 'Direct methods for the detection of reactive oxygen species in human semen samples', Studies on Men's Health and Fertility, Springer, New York 275-299 (2012) [B1]
2010Aitken RJ, Baker MA, De Iuliis GN, Nixon B, 'New insights into sperm physiology and pathology', Fertility Control, Springer, Berlin 99-115 (2010) [B1]
2007Aitken RJ, Roman SD, Baker MA, De Iuliis GN, 'Redox regulation of DNA damage in the male germ line', Male-Mediated Developmental Toxicity, Royal Society of Chemistry, London, United Kingdom 197-209 (2007) [B1]
Show 2 more

Journal article (58 outputs)

YearCitationAltmetricsLink
2014Aitken RJ, Smith TB, Jobling MS, Baker MA, De Iuliis GN, 'Oxidative stress and male reproductive health', ASIAN JOURNAL OF ANDROLOGY, 16 31-38 (2014)
2013Aitken RJ, Baker MA, 'Causes and consequences of apoptosis in spermatozoa; contributions to infertility and impacts on development', International Journal of Developmental Biology, 57 265-272 (2013) [C1]
2013Velkov T, Soon RL, Chong PL, Huang JX, Cooper MA, Azad MAK, et al., 'Molecular basis for the increased polymyxin susceptibility of Klebsiella pneumoniae strains with under-acylated lipid A', Innate Immunity, 19 265-277 (2013) [C1]
2013Baker MA, Weinberg AS, Hetherington L, Velkov T, Aitken RJ, 'Post-ejaculatory changes in the metabolic status of rat spermatozoa as measured by GC-MS', Metabolomics, 9 708-721 (2013) [C1]
2013Carbone V, Kim H, Huang JX, Baker MA, Ong C, Cooper MA, et al., 'Molecular characterization of the receptor binding structure-activity relationships of influenza B virus hemagglutinin', Acta Virologica: international journal, 57 313-332 (2013) [C1]
2013Miyamoto Y, Baker MA, Whiley PA, Arjomand A, Ludeman J, Wong C, et al., 'Towards delineation of a developmental alpha-importome in the mammalian male germline', BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1833 731-742 (2013) [C1]
2013Rockman S, Camuglia S, Vandenberg K, Ong C, Baker MA, Nation RL, et al., 'Reverse engineering the antigenic architecture of the haemagglutinin from influenza H5N1 clade 1 and 2.2 viruses with fine epitope mapping using monoclonal antibodies', Molecular Immunology, 53 435-442 (2013) [C1]
2013Velkov T, Ong C, Baker MA, Kim H, Li J, Nation RL, et al., 'The antigenic architecture of the hemagglutinin of influenza H5N1 viruses', Molecular Immunology, 56 705-719 (2013) [C1]
2013Aitken RJ, Baker MA, 'Oxidative stress, spermatozoa and leukocytic infiltration: Relationships forged by the opposing forces of microbial invasion and the search for perfection', Journal of Reproductive Immunology, 100 11-19 (2013) [C1]
2013Smith TB, Baker MA, Connaughton HS, Aitken RJ, Habenicht U, 'Functional deletion of Txndc2 and Txndc3 increases the susceptibility of spermatozoa to age-related oxidative stress', Free Radical Biology and Medicine, 65 872-881 (2013)
2013Baker MA, Naumovski N, Hetherington L, Weinberg A, Velkov T, Aitken RJ, 'Head and flagella subcompartmental proteomic analysis of human spermatozoa', PROTEOMICS, 13 61-74 (2013)
2013Velkov T, Deris ZZ, Huang JX, Azad MAK, Butler M, Sivanesan S, et al., 'Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae', Innate Immunity, (2013)
2013Aitken RJ, Smith TB, Lord T, Kuczera L, Koppers AJ, Naumovski N, et al., 'On methods for the detection of reactive oxygen species generation by human spermatozoa: analysis of the cellular responses to catechol oestrogen, lipid aldehyde, menadione and arachidonic acid', ANDROLOGY, 1 192-205 (2013)
2012Aitken RJ, Whiting SJ, De Iuliis GN, McClymont SL, Mitchell LA, Baker MA, 'Electrophilic aldehydes generated by sperm metabolism activate mitochondrial reactive oxygen species generation and apoptosis by targeting succinate dehydrogenase', Journal of Biological Chemistry, 287 33048-33060 (2012) [C1]
2012Huang JX, Cooper MA, Baker MA, Azad MAK, Nation RL, Li J, Velkov T, 'Drug-binding energetics of human alpha-1-acid glycoprotein assessed by isothermal titration calorimetry and molecular docking simulations', Journal of Molecular Recognition, 25 642-656 (2012) [C1]
2012Baker MA, Hetherington L, Weinberg AS, Naumovski N, Velkov T, Pelzing M, et al., 'Analysis of phosphopeptide changes as spermatozoa acquire functional competence in the epididymis demonstrates changes in the post-translational modification of Izumo1', Journal of Proteome Research, 11 5252-5264 (2012) [C1]
2012Huang JX, Azad MAK, Yuriev E, Baker MA, Nation RL, Li J, et al., 'Molecular characterization of lipopolysaccharide binding to human a-1-acid glycoprotein', Journal of Lipids, - 1-15 (2012) [C1]
2012Redgrove KA, Nixon B, Baker MA, Hetherington L, Baker G, Liu D-Y, Aitken RJ, 'The molecular chaperone HSPA2 plays a key role in regulating the expression of sperm surface receptors that mediate sperm-egg recognition', Plos One, 7 1-16 (2012) [C1]
2012Baker MA, Nixon B, Naumovski N, Aitken RJ, 'Proteomic insights into the maturation and capacitation of mammalian spermatozoa', Systems Biology in Reproductive Medicine, 58 211-217 (2012) [C1]
2012Aitken RJ, De Iuliis GN, Gibb Z, Baker MA, 'The Simmet lecture: New horizons on an old landscape - oxidative stress, DNA damage and apoptosis in the male germ line', Reproduction in Domestic Animals, 47 7-14 (2012) [C2]
2011Baker MA, Smith ND, Hetherington L, Pelzing M, Condina MR, Aitken RJ, 'Use of titanium dioxide to find phosphopeptide and total protein changes during epididymal sperm maturation', Journal of Proteome Research, 10 1004-1017 (2011) [C1]
2011Baker MA, 'The 'omics revolution and our understanding of sperm cell biology', Asian Journal of Andrology, 13 6-10 (2011) [C1]
2011Dun MD, Smith ND, Baker MA, Lin M, Aitken RJ, Nixon B, 'The chaperonin containing TCP1 complex (CCT/TRiC) is involved in mediating sperm-oocyte interaction', Journal of Biological Chemistry, 286 36875-36887 (2011) [C1]
2011Aitken RJ, Baker MA, 'Cell biology of human spermatozoa: Lessons from the Proteome', Australian Biochemist, 42 12-15 (2011) [C3]

Co-authors: John Aitken

2010Baker MA, Smith ND, Hetherington L, Taubman K, Graham ME, Robinson PJ, Aitken RJ, 'Label-free quantitation of phosphopeptide changes during rat sperm capacitation', Journal of Proteome Research, 9 718-729 (2010) [C1]
2010Baker MA, Reeves GM, Hetherington L, Aitken RJ, 'Analysis of proteomic changes associated with sperm capacitation through the combined use of IPG-strip pre-fractionation followed by RP chromatography LC-MS/MS analysis', Proteomics, 10 482-495 (2010) [C1]
2009Baker MA, Hetherington L, Curry BJ, Aitken RJ, 'Phosphorylation and consequent stimulation of the tyrosine kinase c-Abl by PKA in mouse spermatozoa: Its implications during capacitation', Developmental Biology, 333 57-66 (2009) [C1]
2009Ewen KA, Baker MA, Wilhelm D, Aitken RJ, Koopman P, 'Global survey of protein expression during gonadal sex determination in mice', Molecular & Cellular Proteomics, 8 2624-2641 (2009) [C1]
2009Baker MA, Aitken RJ, 'Proteomic insights into spermatozoa: Critiques, comments and concerns', Expert Review of Proteomics, 6 691-705 (2009) [C1]
2008Aitken RJ, Baker MA, 'The role of proteomics in understanding sperm cell biology', International Journal of Andrology, 31 295-302 (2008) [C1]
2008Baker MA, Hetherington L, Reeves GM, Muller J, Aitken RJ, 'The rat sperm proteome characterized via IPG strip prefractionation and LC-MS/MS identification', Proteomics, 8 2312-2321 (2008) [C1]
2008Aitken RJ, Baker MA, Doncel GF, Matzuk MM, Mauck CK, Harper MJK, 'As the world grows: Contraception in the 21st century', Journal of Clinical Investigation, 118 1330-1343 (2008) [C1]
2008Baker MA, Hetherington L, Reeves GM, Aitken RJ, 'The mouse sperm proteome characterized via IPG strip prefractionation and LC-MS/MS identification', Proteomics, 8 1720-1730 (2008) [C1]
2008Aitken RJ, Hughes LM, Griffith R, Baker MA, 'Bridging the gap between male and female fertility control; contraception-on-demand', Contraception, 78 S28-S35 (2008) [C1]
2008Mitchell LA, Nixon B, Baker MA, Aitken RJ, 'Investigation of the role of SRC in capacitation-associated tyrosine phosphorylation of human spermatozoa', Molecular Human Reproduction, 14 235-243 (2008) [C1]
2007Aitken RJ, Nixon B, Lin M, Koppers AJ, Lee YH, Baker MA, 'Proteomic changes in mammalian spermatozoa during epididymal maturation', Asian Journal of Andrology, 9 554-564 (2007) [C1]
2007Baker MA, Reeves GE, Hetherington L, Muller J, Baur I, Aitken RJ, 'Identification of gene products present in Triton X-100 soluble and insoluble fractions of human spermatozoa lysates using LC-MS/MS analysis', Proteomics Clinical Applications, 1 524-532 (2007) [C1]
2006Aitken RJ, Baker MA, 'Oxidative stress, sperm survival and fertility control', Molecular and Cellular Endocrinology, 250 66-69 (2006) [C1]
2006Lin M, Lee YH, Xu W, Baker MA, Aitken RJ, 'Ontogeny of tyrosine phosphorylation-signaling pathways during spermatogenesis and epididymal maturation in the mouse', Biology of Reproduction, 75 588-597 (2006) [C1]
2006Baker MA, Hetherington L, Aitken RJ, 'Identification of SRC as a key PKA-stimulated tyrosine kinase involved in the capacitation-associated hyperactivation of murine spermatozoa', Journal of Cell Science, 119 3182-3192 (2006) [C1]
2005Baker MA, Krutskikh A, Curry BJ, Hetherington L, Aitken RJ, 'Identification of cytochrome-b5 reductase as the enzyme responsible for NADH-dependent lucigenin chemiluminescence in human spermatozoa', Biology of Reproduction, 73 334-342 (2005) [C1]
2005Baker MA, Aitken RJ, 'Reactive oxygen species in spermatozoa: methods for monitoring and significance for the origins of genetic disease and infertility', Reproductive Biology and Endocrinology, 3 9 (2005) [C1]
2005Baker MA, Witherdin RF, Hetherington L, Cunningham KA, Aitken RJ, 'Identification of post-translational modifications that occur during sperm maturation using difference in two-dimensional gel electrophoresis', Proteomics, 5 1003-1012 (2005) [C1]
2004Baker MA, Hetherington L, Ecroyd HW, Roman SD, Aitken RJ, 'Analysis of the mechanism by which calcium negatively regulates the tyrosine phoshorylation cascade associated with sperm capacitation', Journal of Cell Science, 117 211-222 (2004) [C1]
2004Baker MA, Krutskikh A, Curry BJ, McLaughlin EA, Aitken RJ, 'Identification of Cytochrome P450-Reductase as the Enzyme Responsible for NADPH-Dependent Lucigenin and Tetrazolium Salt Reduction in Rat Epididymal Sperm Preparations', Biology of Reproduction, 71 307-318 (2004) [C1]
2004Aitken RJ, Baker MA, O'Bryan M, 'Shedding Light on Chemiluminescence: The Application of Chemiluminescence in Diagnostic Andrology', Journal of Andrology, 25 455-465 (2004) [C1]

Co-authors: John Aitken

2004Aitken RJ, Ryan AL, Baker MA, McLaughlin EA, 'Redox activity associated with the maturation and capacitation of mammalian spermatozoa', Free Radical Biology and Medicine, 36 994-1010 (2004) [C1]
2004Sidhu KS, Mate KE, Gunasekera T, Veal D, Hetherington L, Baker MA, et al., 'A flow cytometric assay for global estimation of tyrosine phosphorylation associated with capacitation of spermatozoa from two marsupial species, the tammar wallaby (Macropus eugenii) and the brushtail possum (Trichosurus vulpecula)', Reproduction, 127 95-103 (2004) [C1]
2004Baker MA, Aitken RJ, 'The importance of redox regulated pathways in sperm cell biology', Molecular and Cellular Endocrinology, 216 47-54 (2004) [C1]
2004Aitken RJ, Baker MA, 'Oxidative stress and male reproductive biology', Reproduction, Fertility and Development, 16 581-588 (2004) [C1]
2004Baker MA, Lane DJR, Ly JD, Lawen A, De Pinto V, 'VDAC1 Is a Transplasma Membrane NADH-Ferricyanide Reductase', Journal of Biological Chemistry, 279 4811-4819 (2004)
2004Baker MA, Ly JD, Lawen A, 'Characterization of VDAC1 as a plasma membrane NADH-oxidoreductase', BIOFACTORS, 21 215-221 (2004)
2003Aitken RJ, Baker MA, Sawyer DE, 'Oxidative stress in the male germ line and its role in the aetiology of male infertility and genetic disease', Reproductive BioMedicine, 7 65-70 (2003) [C1]

Co-authors: John Aitken

2003Baker MA, Krutskikh A, Aitken RJ, 'Biochemical entities involved in reactive oxygen species generation by human spermatozoa', Protoplasma, 145-151 (2003) [C1]
2003Baker MA, Lewis B, Hetherington L, Aitken RJ, 'Development of the Signalling Pathways Associated With Sperm Capacitation During Epididymal Maturation', Molecular Reproduction and Development, 446-457 (2003) [C1]
2003Aitken RJ, Ryan AL, Curry BJ, Baker MA, 'Multiple forms of redox activity in populations of human spermatozoa', Molecular Human Reproduction, 9 645-661 (2003) [C1]
2002Aitken RJ, Baker MA, 'Reactive oxygen species generation by human spermatozoa: a continuing enigma', International Journal of Andrology, 25 191-194 (2002) [C1]

Co-authors: John Aitken

2002Baker MA, Grubb D, Lawen A, 'Didemnin B induces apoptosis in proliferating but not resting peripheral blood mononuclear cells', Apoptosis: an international journal on programmed cell death, 407-412 (2002) [C1]
Show 55 more

Conference (18 outputs)

YearCitationAltmetricsLink
2013Baker M, Aitken J, 'ANALYSIS OF PHOSPHOPEPTIDE CHANGES AS SPERMATOZOA ACQUIRE FUNCTIONAL COMPETENCE IN THE EPIDIDYMIS DEMONSTRATES CHANGES IN THE POST-TRANSLATIONAL MODIFICATION OF IZUMO1', ANDROLOGY (2013) [E3]
2012Kongmanas K, Sugeng C, Souda P, Faull K, Kitajima K, Aitken RJ, et al., 'Proteomic analysis of sperm anterior head plasma membrane: Unfolding the molecular components underlying sperm-egg interaction', Reproduction in Domestic Animals, Vancouver, Canada (2012) [E3]

Co-authors: John Aitken

2012Nixon B, Redgrove KA, Baker MA, Aitken RJ, 'The role of molecular chaperones in regulating human sperm-egg recognition', Abstracts. The Annual Scientific Meeting of the Endocrine Society of Australia and the Society for Reproductive Biology 2012, Gold Coast, QLD (2012) [E3]
2012Aitken RJ, Nixon B, Redgrove KA, Dun M, Baker MA, 'The molecular origins of defective sperm function', HUMAN REPRODUCTION, Istanbul, TURKEY (2012) [E3]
2008Baker M, Hetherington L, Reeves G, Smith N, Aitken R, 'Comparative and phospho proteomics: Identification of protein changes during sperm maturation', BIOLOGY OF REPRODUCTION, Kona, HI (2008) [E3]
2008Baker MA, Hetherington L, Reeves GM, Smith ND, Aitken RJ, 'Comparative and phospho proteomics: Identification of protein changes during sperm maturation', Proceedings of 41st Annual Meeting of the Society for the Study of Reproduction. "Reproductive Biology: Basic Discoveries that Affect Our Lives", Kailua-Kona, Hawaii (2008) [E3]

Co-authors: John Aitken

2008Mitchell L, Nixon B, Baker M, Aitken R, 'Investigation of the role of SRC in capacitation associated tyrosine phosphorylation of human spermatozoa', BIOLOGY OF REPRODUCTION, Kona, HI (2008) [E3]
2007Baker MA, 'The proteomic analysis of sperm maturation', Gordon Research Conferences: Fertilization & Activation of Development. Program, Plymouth, UK (2007) [E3]
2006Baker MA, Reeves GE, Aitken RJ, 'New Approaches Towards the Proteomic Analysis of the Human Spermatozoon', Book of Abstracts, Lorne, Victoria, Australia (2006) [E3]

Co-authors: John Aitken

2006Aitken RJ, Baker MA, Lee YH, Lin M, Nixon B, 'Proteomic Changes in Mouse Spermatozoa During Epididymal Transit', Abstracts, Chatel-Guyon, Auvergne, France (2006) [E3]
2006Baker MA, Curry BJ, Aitken RJ, 'Inactivation of C-ABL Via PKA During Capacitation of Mouse Spermatozoa', Book of Abstracts, Lorne, Victoria, Australia (2006) [E3]

Co-authors: John Aitken

2006Baker MA, Reeves GM, Aitken RJ, 'New approaches towards the proteomic analysis of the human spermatozoon', Book of Abstracts, Chicago, Illinois (2006) [E3]

Co-authors: John Aitken

2006Baker MA, Reeves GM, Aitken RJ, 'New approaches towads the proteomic analysis of the human spermatozoon', JOURNAL OF ANDROLOGY, Chicago, IL (2006)
2005Baker MA, Aitken RJ, 'Identification of PP60C-SRC as the enzyme responsible for tyrosine phosphorylation and consequent hyperactivation during mouse sperm capacitation', JOURNAL OF ANDROLOGY, Seattle, WA (2005)
2005Baker MA, Aitken RJ, 'Identification of PP60C-SRC as the enzyme responsible for tyrosine phosphorylation and consequent hyperactivation during mouse sperm capacitation', JOURNAL OF ANDROLOGY, Seattle, WA (2005)
2003Baker MA, Hetherington L, Ecroyd HW, Roman SD, Aitken RJ, 'Analysis of the mechanism by which calcium negatively regulates the tyrosine phosphorylation cascade associated with sperm capacitation', ComBio Combined Conference Abstracts, Melbourne (2003) [E3]
2002Baker MA, Krutskikh A, Aitken RJ, 'Redox regulation of sperm function', Proceedings of the Thirty-third annual Conference of the Society for Reproductive Biology, Adelaide, SA (2002) [E3]

Co-authors: John Aitken

2002Aitken RJ, Baker MA, Krutskikh A, 'Oxidative stress and redox regulation in the epididymis', Epididymis III. Third International Conference on the Epididymis., Charlottesville, Virginia, USA (2002) [E3]

Co-authors: John Aitken

Show 15 more
Edit

Grants and Funding

Summary

Number of grants24
Total funding$5,263,205

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2013 (2 grants)

Triple Quadrupole Mass Spectrometer with nano-infusion for targeted protein quantification$300,000
Funding Body: University of Newcastle

Project Team
Doctor Mark Baker, Laureate Professor John Aitken, Conjoint Professor Bogdan Dlugogorski, Professor Hubert Hondermarck
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$300,00020132013
GNo:G1200137

NucleoCounter SP100$14,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Laureate Professor John Aitken, Associate Professor Brett Nixon, Doctor Shaun Roman, Doctor Mark Baker, Doctor Geoffry De Iuliis, Doctor Lisa Mitchell, Doctor Matthew Jobling, Doctor Zamira Gibb, Mr Nenad Naumovski
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$14,00020132013
GNo:G1201175

2012 (3 grants)

Understanding sperm motility for infertility and contraceptive purposes$432,568
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Mark Baker
SchemeRole
Career Development FellowshipsChief Investigator
Total AmountFunding StartFunding Finish
$432,56820122015
GNo:G1100192

BMG SPECTROstar Nano$15,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Laureate Professor John Aitken, Professor Eileen McLaughlin, Ms Belinda Nixon, Doctor Shaun Roman, Doctor Mark Baker, Doctor Geoffry De Iuliis, Doctor Lisa Mitchell, Doctor Matthew Jobling
SchemeRole
Equipment GrantInvestigator
Total AmountFunding StartFunding Finish
$15,00020122012
GNo:G1100971

PULSE Early Career Researcher$10,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Mark Baker
SchemeRole
PULSE Early Career Researcher GrantChief Investigator
Total AmountFunding StartFunding Finish
$10,00020122012
GNo:G1200578

2011 (5 grants)

Chemical principles underpinning a spermostatic-microbiostatic agent capable of preventing pregnancy and the spread of sexually transmitted disease$735,000
Funding Body: ARC (Australian Research Council)

Project Team
Laureate Professor John Aitken, Doctor Mark Baker, Professor Kenneth Beagley, Professor Adam McCluskey
SchemeRole
Discovery ProjectsInvestigator
Total AmountFunding StartFunding Finish
$735,00020112013
GNo:G1000173

Understanding the Molecular Basis of Epididymal Maturation: How Does the Epididymis Modify Spermatozoa, Allowing them to Recognise the Egg?$565,222
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Mark Baker
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$565,22220112013
GNo:G1000306

An Advanced Mass Spectrometer for Applications in Phospho-Proteomics, Glycomics and Top-Down Sequencing of Proteins$250,000
Funding Body: ARC (Australian Research Council)

Project Team
Doctor Mark Baker, Laureate Professor John Aitken, Professor Roger Smith, Conjoint Professor Keith Jones, Conjoint Professor Ray Rose, Professor Lois Salamonsen
SchemeRole
Linkage Infrastructure Equipment & Facilities (LIEF)Chief Investigator
Total AmountFunding StartFunding Finish
$250,00020112011
GNo:G1000632

3D Ion Trap Mass Spectrometer with ETD for Top Down Proteomics Applications$170,000
Funding Body: University of Newcastle

Project Team
Doctor Mark Baker, Laureate Professor John Aitken
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$170,00020112011
GNo:G1000470

An Advanced Mass Spectrometer for Applications in Phospho-Proteomics, Glycomics and Top-Down Sequencing of Proteins$15,000
Funding Body: Prince Henry's Institute of Medical Research

Project Team
Doctor Mark Baker, Laureate Professor John Aitken, Professor Roger Smith, Conjoint Professor Keith Jones, Conjoint Professor Ray Rose, Professor Lois Salamonsen
SchemeRole
Linkage Infrastructure Equipment & Facilities (LIEF) Partner fundingChief Investigator
Total AmountFunding StartFunding Finish
$15,00020112011
GNo:G1100844

2010 (5 grants)

An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$500,000
Funding Body: ARC (Australian Research Council)

Project Team
Professor Adam McCluskey, Laureate Professor John Aitken, Professor Paul Dastoor, Professor Phillip Robinson, Professor Eileen McLaughlin, Emeritus Professor Geoffrey Lawrance, Professor Marcel Maeder, Professor Hugh Dunstan, Doctor Shaun Roman, Associate Professor Rob Atkin, Doctor Clovia Holdsworth, Doctor Mark Baker, Doctor Nikki Verrills, Professor Gottfried Otting, Associate Professor Brett Nixon, Doctor Xiaojing Zhou, Ms Megan Chircop, Doctor Warwick Belcher
SchemeRole
Linkage Infrastructure Equipment & Facilities (LIEF)Investigator
Total AmountFunding StartFunding Finish
$500,00020102010
GNo:G0190402

An Integrated LC-MS-NMR facility for Applications in Proteomics and Organic Chemistry$280,000
Funding Body: University of Newcastle

Waters, Ultra high performance liquid chromatography system (nano-Aquity) $30,000
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Mark Baker, Laureate Professor John Aitken, Professor Adam McCluskey, Associate Professor Brett Nixon, Emeritus Professor John Rostas, Professor Eileen McLaughlin
SchemeRole
Equipment GrantChief Investigator
Total AmountFunding StartFunding Finish
$30,00020102010
GNo:G1000051

The design of novel, affinity-based technology to specifically isolate phosphotyrosine-containing pedtides$25,000
Funding Body: Hunter Children`s Research Foundation

Project Team
Doctor Mark Baker, Professor Adam McCluskey
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$25,00020102010
GNo:G0900191

2009 FSIT Award for Research Excellence$2,000
Funding Body: University of Newcastle

Project Team
Doctor Mark Baker
SchemeRole
Award for Research ExcellenceChief Investigator
Total AmountFunding StartFunding Finish
$2,00020102010
GNo:G1000404

2009 (5 grants)

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$495,000
Funding Body: ARC (Australian Research Council)

Identification and characterisation of phosphorylation events taking place during human sperm capacitation$269,250
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Doctor Mark Baker
SchemeRole
Project GrantChief Investigator
Total AmountFunding StartFunding Finish
$269,25020092011
GNo:G0188834

China-Australia therapeutic hypothermia in stroke (CATHS) research program: identification of diagnostic molecular markers and therapeutic targets involved in re-warming related brain injury$230,275
Funding Body: NSW Office for Science & Medical Research

Project Team
Conjoint Professor Chris Levi, Doctor Mark Baker, Doctor Neil Spratt, Emeritus Professor John Rostas
SchemeRole
China-NSW Collaborative Research ProgramInvestigator
Total AmountFunding StartFunding Finish
$230,27520092009
GNo:G0190392

Assessing the significance of the sperm thioredoxins as contraceptive targets for the male$148,096
Funding Body: Contraceptive Research and Development Program

Project Team
Laureate Professor John Aitken, Doctor Mark Baker
SchemeRole
Development of New or Improved Contraceptive ProductsInvestigator
Total AmountFunding StartFunding Finish
$148,09620092009
GNo:G0189339

An Advanced Mass Spectrometry Facility for Applications in Proteomics and Organic Chemistry$50,000
Funding Body: ARC (Australian Research Council)

2008 (1 grants)

PULSE Education Prize$4,000
Funding Body: Hunter Medical Research Institute

Project Team
Doctor Mark Baker
SchemeRole
PULSE Education PrizeChief Investigator
Total AmountFunding StartFunding Finish
$4,00020082008
GNo:G0188535

2007 (3 grants)

2007 Research Fellowship - PRCRS$509,053
Funding Body: University of Newcastle

Project Team
Doctor Mark Baker
SchemeRole
Research FellowshipChief Investigator
Total AmountFunding StartFunding Finish
$509,05320072012
GNo:G0187158

AMPPAII Proposal for completion of the Sptrx KO mice study$198,741
Funding Body: Schering AG

Project Team
Laureate Professor John Aitken, Doctor Mark Baker
SchemeRole
Research NetworksInvestigator
Total AmountFunding StartFunding Finish
$198,74120072007
GNo:G0188468

2007 Research Fellowship Project Grant$15,000
Funding Body: University of Newcastle

Project Team
Doctor Mark Baker
SchemeRole
Fellowship GrantChief Investigator
Total AmountFunding StartFunding Finish
$15,00020072007
GNo:G0188117
Edit

Research Supervision

Number of current supervisions2
Total current UoN PhD EFTSL0.5

For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.

Current Supervision

CommencedProposed
Completion
ProgramSupervisor TypeResearch Title
20142018PhD (Human Physiology)Co-SupervisorDetermining Factors within Cerebro-Spinal Fluid that Influence Intracranial Pressure Post-Stroke
20132017PhD (Biological Sciences)Co-SupervisorAnalysis of Metabolic Mechanisms Controlling Glucose Metabolism in Mammalian Spermatozoa
Edit

Dr Mark Baker

Work Phone(02) 4921 7880
Fax(02) 4921 6308
Email
PositionResearch Fellow
School of Environmental and Life Sciences
Faculty of Science and Information Technology
The University of Newcastle, Australia
Focus AreaBiological Sciences
Office
LS4-42,
Life Sciences,
Callaghan
University Drive
Callaghan NSW 2308
Australia
URL:www.newcastle.edu.au/profile/mark-baker