Staff Profile

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Career Summary

Research

Research keywords

  • Acute and chronic pain
  • Arthritis
  • Inflammatory disorders
  • Nanomedicines
  • Nanotechnology
  • Opioids
  • Peripheral analgesia
  • Targeted drug delivery
  • Therapeutic targeting
  • Translational pain research

Research expertise

Dr Hua has established the Therapeutic Targeting Research Group at The University of Newcastle. Her background as a clinical pharmacist has given her a thorough clinical understanding of therapeutics and disease states, and has allowed her to identify promising research avenues in therapeutics and drug delivery. The research focus of Dr Hua's laboratory is on targeted drug delivery using nanomedicines in biomedical applications, which forms the basis of a number of her research collaborations. More specifically, her research group is focused on translational pain research in the areas of peripheral analgesia and inflammation in acute and chronic pain conditions - incl. rheumatoid arthritis, osteoarthritis, acute tissue injury, and neuropathy. Dr Hua's research expertise covers the areas of formulation, in vitro studies and preclinical in vivo studies. This expertise provides a solid foundation to formulate and evaluate new drug delivery systems and to apply them to pathological disease states, in order to assess potential clinical applicability and novel mechanistic pathways. Her research provides a platform for the translational development of targeted therapeutics that will ultimately provide a novel therapeutic strategy in clinical disease management.

Fields of Research

CodeDescriptionPercentage
110322Rheumatology And Arthritis50
100709Nanomedicine30
111504Pharmaceutical Sciences20

Administrative

Administrative expertise

Course coordinator for PHAR6133 - Pharmacotherapeutics 1

Course coordinator for PHAR6211 - Pharmacy Practice 4

School Representative on the Faculty of Health Progress and Appeals Committee

Pharmaceutics Advisor on the Institutional Biosafety Committee (IBC)

Teaching

Teaching keywords

  • Pharmacotherapeutics
  • Pharmacy Practice

Teaching expertise

Dr Hua BPharm (Hons), PhD, MPS is a full time academic at the School of Biomedical Sciences and Pharmacy, Discipline of Pharmacy. She is a registered pharmacist in Australia and has worked a number of years across various facets of pharmacy, including hospital, community and research. Dr Hua is teaching into the areas of Pharmacotherapeutics and Pharmacy Practice in the Masters of Pharmacy program at The University of Newcastle. Dr Hua strongly believes in the importance of high quality teaching and positive motivation of pharmacy students and junior pharmacists to sustain the quality use of medicines in the community.

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Publications

For publications that are currently unpublished or in-press, details are shown in italics.

Click on a category title below to expand the list of citations for that specific category.

Journal article (13 outputs)

YearCitationAltmetricsLink
2014Hua S, 'Orally administered liposomal formulations for colon targeted drug delivery.', Front Pharmacol, 5 138 (2014)
2014Jobling P, O'Hara K, Hua S, 'Female reproductive tract pain: targets, challenges, and outcomes.', Front Pharmacol, 5 17 (2014)
2014Hua S, 'Comparison of in vitro dialysis release methods of loperamide-encapsulated liposomal gel for topical drug delivery', INTERNATIONAL JOURNAL OF NANOMEDICINE, 9 735-744 (2014)
2013Iwaszkiewicz KS, Schneider JJ, Hua S, 'Targeting peripheral opioid receptors to promote analgesic and anti-inflammatory actions.', Front Pharmacol, 4 132 (2013) [C1]
2013Hua S, Wu SY, 'The use of lipid-based nanocarriers for targeted pain therapies', Frontiers in Pharmacology, 4 NOV (2013) [C1]
2013Hua S, 'Targeting sites of inflammation: intercellular adhesion molecule-1 as a target for novel inflammatory therapies.', Front Pharmacol, 4 127 (2013) [C1]
2013Hua S, Cabot PJ, 'Targeted Nanoparticles that Mimic Immune Cells in Pain Control Inducing Analgesic and Anti-inflammatory Actions: A Potential Novel Treatment of Acute and Chronic Pain Conditions', PAIN PHYSICIAN, 16 E199-E216 (2013) [C1]
2011Hua S, Chang H-I, Davies N, Cabot PJ, 'Targeting of ICAM-1-directed immunoliposomes specifically to activated endothelial cells with low cellular uptake: use of an optimized procedure for the coupling of low concentrations of antibody to liposomes.', Journal of Liposome Research, 21 95-105 (2011) [C1]
2011Witting PK, Song C, Hsu K, Hua S, Parry SN, Rye K, et al., 'The acute phase protein serum amyloid A induces endothelial dysfunction that is inhibited by high-density lipoprotein.', Free Radical Biology and Medicine, 51 1390-1398 (2011) [C1]
2010Hua S, Cabot PJ, 'Mechanisms of peripheral immune-cell-mediated analgesia in inflammation: Clinical and therapeutic implications', Trends in Pharmacological Sciences, 31 427-433 (2010) [C1]
2009Rayner BS, Hua S, Sabaretnam T, Witting PK, 'Nitric oxide stimulates myoglobin gene and protein expression in vascular smooth muscle.', Biochemical Journal, 423 169-177 (2009) [C1]
2009Hua S, Geczy CL, Freedman SB, Witting PK, 'A role for acute-phase serum amyloid A and high-density lipoprotein in oxidative stress, endothelial dysfunction and atherosclerosis.', Redox Report, 14 187-196 (2009) [C1]
2006Hua S, Hermanussen S, Tang L, Monteith GR, Cabot PJ, 'The neural cell adhesion molecule antibody blocks cold water swim stress-induced analgesia and cell adhesion between lymphocytes and cultured dorsal root ganglion neurons', Anesthesia and Analgesia, 103 1558-1564 (2006) [C1]
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Conference (1 outputs)

YearCitationAltmetricsLink
2012Hua S, Cabot PJ, 'Loperamide-formulated immunoliposomes directed towards intercellular adhesion molecule-1 (ICAM-1): A potential tool for specific drug delivery to peripheral inflammatory pain', Abstracts of the 39th Annual Meeting and Exposition of the Controlled Release Society, Quebec, ON (2012) [E3]
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Grants and Funding

Summary

Number of grants8
Total funding$662,037

- Indicates that the researcher may be seeking students for this project.

Click on a grant title below to expand the full details for that specific grant.

2014 (1 grants)

The 4th Annual Symposium of drug Delivery System 2014 (SDDS-2014), Suzhou China, 17 - 20 November 2014$2,000
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Doctor Susan Hua
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,00020142014
GNo:G1400807

2013 (2 grants)

Understanding the regulation of hERG potassium channel in the myometrium at the time of labour$577,956
Funding Body: NHMRC (National Health & Medical Research Council)

Project Team
Professor Roger Smith, Professor Nick Europe-Finner, Doctor Susan Hua
SchemeRole
Project GrantInvestigator
Total AmountFunding StartFunding Finish
$577,95620132015
GNo:G1200367

Leica TP 1020 Automatic Tissue Processor for histology applications$35,000
Funding Body: NHMRC (National Health & Medical Research Council)

2012 (2 grants)

Peripheral immune-derived analgesia: A new target for the treatment of rheumatoid arthritis$20,000
Funding Body: Pharmacy Research Trust of NSW

Project Team
Doctor Susan Hua
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$20,00020122013
GNo:G1101131

The 39th Annual Meeting and Exposition of the Controlled Release Society, Quebec City, Canada, 15 - 18 July 2012$1,500
Funding Body: University of Newcastle - Faculty of Health and Medicine

Project Team
Doctor Susan Hua
SchemeRole
Travel GrantChief Investigator
Total AmountFunding StartFunding Finish
$1,50020122012
GNo:G1200581

2011 (1 grants)

Development of novel targeted drug delivery systems specifically to sites of inflammation and its application to peripheral analgesia and inflammation in chronic arthritic pathologies$15,581
Funding Body: Rebecca L Cooper Medical Research Foundation Ltd

Project Team
Doctor Susan Hua
SchemeRole
Research GrantChief Investigator
Total AmountFunding StartFunding Finish
$15,58120112011
GNo:G1000741

2010 (2 grants)

Development of Novel Targeted Drug Delivery Systems to Sites of Inflammation$7,395
Funding Body: University of Newcastle

Project Team
Doctor Susan Hua
SchemeRole
Early Career Researcher GrantChief Investigator
Total AmountFunding StartFunding Finish
$7,39520102010
GNo:G1000970

Development of Novel Targeted Drug Delivery Systems to Sites of Inflammation$2,605
Funding Body: University of Newcastle

Project Team
Doctor Susan Hua
SchemeRole
Early Career Researcher (Equipment) GrantChief Investigator
Total AmountFunding StartFunding Finish
$2,60520102010
GNo:G1000683
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Research Supervision

Number of current supervisions0

No Supervisions.

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Dr Susan Hua

Work Phone(02) 49854063
Fax(02) 49217903
Email
PositionLecturer
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine
The University of Newcastle, Australia
Focus AreaPharmacy and Experimental Pharmacology
Office
MS126,
Medical Science Building,
Callaghan
University Drive
Callaghan NSW 2308
Australia
URL:www.newcastle.edu.au/profile/susan-hua