Dr Rachel Sutherland

Dr Rachel Sutherland

Conjoint Lecturer

School of Health Sciences (Nutrition and Dietetics)

The clever new science creating widespread community health benefits

By researching chronic disease and implementation science in tandem, Dr Rachel Sutherland is working to ensure the latest health research can benefit entire communities, leading to programs that can be effectively scaled up to reach more people across Australia and the globe.

Image of Rachel Sutherland

Dr Rachel Sutherland is taking a fresh perspective to solving some of the world’s most enduring health challenges, including obesity and sedentary lifestyles. Her research aims to better understand chronic disease and create evidence-based solutions. But it doesn’t stop there. Rachel is also committed to researching the best ways of implementing those solutions into routine care and practice—allowing the latest research to have a direct impact in people’s lives and create community-wide change.

“My health research focuses on preventing chronic disease, with a particular focus on preventing excessive weight gain and obesity via implementing nutrition and physical activity interventions targeting schools (primary and secondary) and parents.

“I am very passionate about ensuring programs are delivered at scale, reach the communities that they would benefit most, and that research is translated and doesn’t just sit idle on the shelf.

“To do this, my research primarily evaluates methods of implementing evidence-based programs at scale—known as implementation science. Essentially, this type of research is conducted to ensure the community benefits from research that has been shown to be effective.”

When the rubber hits the road

Every year, talented researchers undertake extraordinarily valuable research with the potential to save and improve lives. The problem, Rachel says, is that much of this research is never delivered in practice, even when it’s proven to be effective.

“Unfortunately, research shows that it generally takes 17 years for research to benefit the community. Research that can’t be implemented successfully rarely helps the community. Implementation science aims to bridge this evidence-to-practice gap.”

To mobilise more research in Australia, Rachel and her peers are committed to investigating what stops research from translating into practice and, based on this knowledge, design evidence-based strategies for implementing research more effectively.

“As an implementation researcher, you need to be able to listen, communicate and understand a setting and the barriers to implementation. Unless you understand a setting and work in partnership, implementation at scale is not possible and not sustainable. It is essential to have commitment from partners and a clear vision from the outset of how the research can be translated.”

Rachel’s work in the pioneering field of implementation science neatly complements her health research, creating a powerful combination that enables the most exciting research findings to translate into innovative programs, policies and initiatives with widespread community health benefits.

“The field of implementation science and the science of scaling up is relatively new. This means new methods and measures are emerging and need to be developed. I’m excited to use implementation science to scale up nutrition and physical activity interventions to the community.

“My overarching aim is to prevent problematic weight gain and obesity before chronic disease is established and to maintain the health and wellbeing of children and families.”

Setting children on the right path

Rachel’s PhD research, completed in 2017, focused on the public health epidemic of obesity, a disease that can contribute to other chronic illnesses, like type 2 diabetes and some cancers. Her work created waves in the health research community; it was the first trial internationally to demonstrate an increase in physical activity and a reduction in unhealthy weight gain using cost-effective methods targeting disadvantaged adolescents.

Her PhD work was identified in the NSW Premier’s implementation plan for the prevention of obesity in children and informed Physical Activity 4 Everyone, a new school program that is now being implemented in schools across four local health districts in NSW, helping secondary schools teach healthy habits that can continue throughout a child’s life.

“As a result of the program, up to 25,000 adolescents are now attending NSW secondary schools that support physical activity and help adolescents maintain their physical activity levels in critical years when activity levels generally decline. This has a range of health, wellbeing and educational benefits.”

Rachel is currently involved in the scalable nutrition program SWAP IT, which helps parents pack healthy school lunchboxes for their children. Parents are encouraged and supported to swap out nutrient-poor foods for healthier alternatives.

“The food children consume at school impacts on their concentration, health and wellbeing—now and into the future. More than 85 per cent of school children take a packed lunch to school every day; however, packed inside are more than three servings of energy-dense, nutrition-poor snack foods.

“Making one to two simple swaps every day in the lunchbox can have an enormous impact at a population level, both in terms of health, education and wellbeing.”

Rachel’s program of work is being conducted in collaboration with industry partner, Skoolbag. It has received backing from the NSW Ministry of Health to evaluate the program’s health benefits, as well as funding from the NIB Foundation to scale up the program across the Hunter New England region.

Rachel’s work often takes place in partnership with multiple key stakeholders, who all play an integral role in seeing inventions implemented successfully.

“For implementation and scale-up to be successful, research and interventions need to be co-developed with partners across a range of settings where health may not be their core business. This takes time, communication and a great deal of understanding of how settings and organisations work.

“It’s exciting to work in partnership with stakeholders across a range of settings and see the community benefit from our research. Having the research delivered at scale to the community, and translated into tangible solutions, is the most important aspect of my work.”

Image of Rachel Sutherland

The clever new science creating widespread community health benefits

By researching chronic disease and implementation science in tandem, Dr Rachel Sutherland is working to ensure the latest health research can benefit entire communities, leading to programs that can be effectively scaled up to reach more people across Australia and…

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Career Summary

Biography

Dr Rachel Sutherland is an NHMRC Research Fellow with the University of Newcastle’s School of Medicine and Public Health (Nutrition and Dietetics). An influential translational researcher, her work is focused on the development and evaluation of implementation research interventions to scale up population health services. Dr Sutherland is also an experienced Public Health Nutritionist, Health Promotion Practitioner and Program Manager and has worked in the field of Population Health and Public Health Nutrition for more than 15 years.

In 2017, Dr Sutherland was awarded her PhD in the area of school-based interventions and student behaviour change. Her PhD and postdoctoral research led to the design, implementation and evaluation of the secondary school program Physical Activity 4 Everyone (PA4E1), which was the first successful trial worldwide to increase adolescent physical activity and improve the weight status of disadvantaged adolescents. The PA4E1 program is now listed in the NSW Premier’s Priority Implementation Plan. The success of Dr Sutherland’s postdoctoral work led to her assignment as lead investigator, working with Local Health Districts, to scale up the PA4E1 program across NSW in more than 50 secondary schools.

As an early career researcher, Dr Sutherland has held lead roles on a number of research projects and trials focused on childhood obesity prevention across the research translation spectrum, including feasibility studies, efficacy trials, hybrid implementation trials and the scale-up of a program known as SWAP IT, which supported parents of primary school children to swap nutrition-poor lunchbox foods for healthier food options.

Dr Sutherland previously held the role of Program Co-Director on the Good for Kids. Good for Life program, for which she developed, implemented and evaluated aspects of the children’s services stream and primary school stream of the program. Spanning six years, the program of work was Australia’s largest childhood obesity prevention program and received funding of more than $7.5 million.

Dr Sutherland has delivered presentations at more than 40 national and international conferences, and published more 60 peer-reviewed journal articles, two government reports and an invited book chapter. In the past five years, she has been awarded over $3 million from competitive grants including the NSW Ministry of Health Translational Research Grant Scheme, Australian Research Council and Medical Research Futures Fund.

Collaborations: As a research practitioner, Dr Sutherland collaborates with key stakeholders in both practice and research fields to produce programs, research and dissemination activities with international impact. This includes collaborating with stakeholders from the Department of Education, Catholic Schools Office, Association of Independent Schools and research organisations within Australia and internationally including the UK and Canada. Internationally, Dr Sutherland also facilitates the global research networking and mentoring of physical activity and nutrition researchers via her role in co-ordinating the webinar series for the ECR network of the International Society of Physical Activity and Health.

Community engagement: Within her integrated research and practice role, Dr Sutherland regularly engages with the community to co-produce, design and disseminate research findings. She is responsible for delivering health promotion services to primary (n=450) and secondary schools (n-105). She also delivers workshops to school principals, parents and teachers. Dr Sutherland regularly provides lectures at the University of Newcastle and supervisors undergraduate and postgraduate students.


Qualifications

  • Doctor of Philosophy, University of Newcastle
  • Bachelor of Health Science (Nutrition & Dietetics), University of Newcastle
  • Master of Public Health, Curtin University

Keywords

  • Implementation Science
  • Nutrition
  • Obesity Prevention
  • Physical Activity
  • Public Health
  • Translation

Fields of Research

Code Description Percentage
090899 Food Sciences not elsewhere classified 65
111799 Public Health and Health Services not elsewhere classified 35

Professional Experience

Professional appointment

Dates Title Organisation / Department
21/1/2002 - 17/11/2019 Nutriiton Program Manager Hunter New England Population Health
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Journal article (93 outputs)

Year Citation Altmetrics Link
2020 Nathan NK, Sutherland RL, Hope K, McCarthy NJ, Pettett M, Elton B, et al., 'Implementation of a school physical activity policy improves student physical activity levels: Outcomes of a cluster-randomized controlled trial', Journal of Physical Activity and Health, 17 1009-1018 (2020)

© 2020 Human Kinetics Publishers Inc.. All rights reserved. Aim: To assess the impact of a multistrategy intervention designed to improve teachers' implementation of a school... [more]

© 2020 Human Kinetics Publishers Inc.. All rights reserved. Aim: To assess the impact of a multistrategy intervention designed to improve teachers' implementation of a school physical activity (PA) policy on student PA levels. Methods: A cluster-randomized controlled trial was conducted in 12 elementary schools. Policy implementation required schools to deliver 150 minutes of organized PA for students each week via physical education, sport, or class-based activities such as energizers. Schools received implementation support designed using the theoretical domains framework to help them implement the current policy. Results: A total of 1,502 children in kindergarten to grade 6 participated. At follow-up compared with control, students attending intervention schools had, measured via accelerometer, significantly greater increases in school day counts per minute (97.5; 95% confidence interval [CI], 64.5 to 130.4; P <.001) and moderate to vigorous physical activity (MVPA) (3.0; 95% CI, 2.2-3.8, P <.001) and a greater decrease in sedentary time (-2.1; 95% CI, -3.9 to -0.4, P =.02) per school day. Teachers in intervention schools delivered significantly more minutes (36.6 min) of PA to their students at follow-up (95% CI, 2.7-70.5, P =.04). Conclusions: Supporting teachers to implement a PA policy improves student PA. Additional strategies may be needed to support teachers to implement activities that result in larger gains in student MVPA.

DOI 10.1123/jpah.2019-0595
Co-authors Alix Hall, Kathryn L Reilly, John Wiggers, Luke Wolfenden, Nicole Nathan
2020 Mclaughlin M, Duff J, Sutherland R, Campbell E, Wolfenden L, Wiggers J, 'Protocol for a mixed methods process evaluation of a hybrid implementation-effectiveness trial of a scaled-up whole-school physical activity program for adolescents: Physical Activity 4 Everyone (PA4E1)', TRIALS, 21 (2020)
DOI 10.1186/s13063-020-4187-5
Citations Scopus - 1Web of Science - 1
Co-authors Matthew Mclaughlin Mc, Luke Wolfenden, Jed Duff, John Wiggers
2020 Nathan N, Murawski B, Hope K, Young S, Sutherland R, Hodder R, et al., 'The efficacy of workplace interventions on improving the dietary, physical activity and sleep behaviours of school and childcare staff: A systematic review', International Journal of Environmental Research and Public Health, 17 1-24 (2020) [C1]

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. There is a need for effective interventions that improve the health and wellbeing of school and childcare staff. This rev... [more]

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. There is a need for effective interventions that improve the health and wellbeing of school and childcare staff. This review examined the efficacy of workplace interventions to improve the dietary, physical activity and/or sleep behaviours of school and childcare staff. A secondary aim of the review was to assess changes in staff physical/mental health, productivity, and students¿ health behaviours. Nine databases were searched for controlled trials including randomised and non-randomised controlled trials and quasi-experimental trials published in English up to October 2019. PRISMA guidelines informed screening and study selection procedures. Data were not suitable for quantitative pooling. Of 12,396 records screened, seven articles (based on six studies) were included. Most studies used multi-component interventions including educational resources, work-based wellness committees and planned group practice (e.g., walking groups). Multiple outcomes were assessed, findings were mixed and on average, there was moderate risk of bias. Between-group differences in dietary and physical activity behaviours (i.e., fruit/vegetable intake, leisure-time physical activity) favoured intervention groups, but were statistically non-significant for most outcomes. Some of the studies also showed differences favouring controls (i.e., nutrient intake, fatty food consumption). Additional robust studies testing the efficacy of workplace interventions to improve the health of educational staff are needed.

DOI 10.3390/ijerph17144998
Co-authors Nicole Nathan, Luke Wolfenden, Rebecca Hodder, Kathryn L Reilly, Beatrice Murawski, Serene Yoong, Flora Tzelepis
2020 Brown A, Barnes C, Byaruhanga J, McLaughlin M, Hodder RK, Booth D, et al., 'Effectiveness of technology-enabled knowledge translation strategies in improving the use of research in public health: Systematic review', Journal of Medical Internet Research, 22 (2020) [C1]
DOI 10.2196/17274
Co-authors Nicole Nathan, Luke Wolfenden, Matthew Mclaughlin Mc, Rebecca Hodder
2020 Wolfenden L, Williams CM, Kingsland M, Yoong SL, Nathan N, Sutherland R, Wiggers J, 'Improving the impact of public health service delivery and research: a decision tree to aid evidence-based public health practice and research', Australian and New Zealand Journal of Public Health, 44 331-332 (2020)
DOI 10.1111/1753-6405.13023
Co-authors Nicole Nathan, Luke Wolfenden, Christopher M Williams, Serene Yoong, John Wiggers
2020 Yoong SL, Grady A, Wiggers JH, Stacey FG, Rissel C, Flood V, et al., 'Child-level evaluation of a web-based intervention to improve dietary guideline implementation in childcare centers: a cluster-randomized controlled trial.', Am J Clin Nutr, 111 854-863 (2020)
DOI 10.1093/ajcn/nqaa025
Co-authors Luke Wolfenden, Alice Grady, Serene Yoong, Rebecca Wyse, John Wiggers
2020 Mclaughlin M, Atkin AJ, Starr L, Hall A, Wolfenden L, Sutherland R, et al., 'Worldwide surveillance of self-reported sitting time: a scoping review.', The international journal of behavioral nutrition and physical activity, 17 (2020) [C1]
DOI 10.1186/s12966-020-01008-4
Co-authors Alix Hall, John Wiggers, Luke Wolfenden, Matthew Mclaughlin Mc
2020 Sutherland R, Nathan N, Brown A, Yoong S, Reynolds R, Walton A, et al., 'A cross-sectional study to determine the energy density and nutritional quality of primary-school children's lunchboxes.', Public Health Nutr, 23 1108-1116 (2020)
DOI 10.1017/S1368980019003379
Co-authors Serene Yoong, Luke Wolfenden, Nicole Nathan
2020 Sutherland R, Campbell E, McLaughlin M, Nathan N, Wolfenden L, Lubans DR, et al., 'Scale-up of the Physical Activity 4 Everyone (PA4E1) intervention in secondary schools: 12-month implementation outcomes from a cluster randomized controlled trial.', Int J Behav Nutr Phys Act, 17 100 (2020) [C1]
DOI 10.1186/s12966-020-01000-y
Co-authors John Wiggers, David Lubans, Andrew Searles, Christopher Oldmeadow, Matthew Mclaughlin Mc, Jenna Hollis, Nicole Nathan, Philip Morgan, Luke Wolfenden
2020 Yoong SL, Hall A, Stacey F, Grady A, Sutherland R, Wyse R, et al., 'Nudge strategies to improve healthcare providers' implementation of evidence-based guidelines, policies and practices: a systematic review of trials included within Cochrane systematic reviews', IMPLEMENTATION SCIENCE, 15 (2020) [C1]
DOI 10.1186/s13012-020-01011-0
Co-authors Amy Anderson, Luke Wolfenden, Alice Grady, Rebecca Wyse, Serene Yoong, Nicole Nathan, Alix Hall
2020 Pearson N, Wolfenden L, Finch M, Yoong SL, Kingsland M, Nathan N, et al., 'A cross-sectional study of packed lunchbox foods and their consumption by children in early childhood education and care services.', Nutr Diet, (2020)
DOI 10.1111/1747-0080.12632
Co-authors Serene Yoong, Nicole Nathan, Luke Wolfenden
2020 Shoesmith A, Hall A, Hope K, Sutherland R, Hodder RK, Trost SG, et al., 'Associations between in-school-hours physical activity and child health-related quality of life: A cross-sectional study in a sample of Australian primary school children', Preventive Medicine Reports, 20 (2020)

© 2020 The Author(s) The aim of the current study was to examine the association between Australian primary school children&apos;s objectively measured in-school-hours weekly phys... [more]

© 2020 The Author(s) The aim of the current study was to examine the association between Australian primary school children's objectively measured in-school-hours weekly physical activity (PA) and their health-related quality of life (HRQoL). A cross-sectional study of 1128 Grade 2 and 3 children, aged 7¿9 years, from 62 primary schools was conducted in New South Wales, Australia between October 2017 and April 2018. Children's PA was assessed via an accelerometer worn for five days during school hours. Their parents completed a telephone interview, answering demographic, child HRQoL and out-of-school-hours PA questions. Children's in-school-hours PA was classified as total PA and moderate-to-vigorous PA (MVPA). HRQoL scores were aggregated and reported at the high construct level domains (Total Quality of Life (Total HRQoL), Physical and Psychosocial Health Summary Scores). Multiple linear mixed regression analyses accounting for clustering were conducted to evaluate the association between children's in-school-hours weekly PA and their HRQoL. After adjusting for potential confounders, significant positive associations were found between children's in-school-hours weekly total PA and Total HRQoL (0.62 units, 95% CI: 0.29; 0.94, p < 0.001), Physical (0.71 units, 95% CI: 0.38; 1.04, p = 0.001) and Psychosocial (0.58 units, 95% CI: 0.19; 0.97, p = 0.004) scores, with a stronger association observed between average weekly MVPA than average weekly total PA. There were also positive associations between PA and HRQoL for each sex when analysed separately. Our findings demonstrate a positive association between children's objectively-measured in-school-hours PA and parent-reported child HRQoL, strengthening evidence supporting the continued implementation of school-based PA programs for broader health outcomes.

DOI 10.1016/j.pmedr.2020.101179
Co-authors Nicole Nathan, Alix Hall, Rebecca Hodder
2020 Ahmadi MN, Nathan N, Sutherland R, Wolfenden L, Trost SG, 'Non-wear or sleep? Evaluation of five non-wear detection algorithms for raw accelerometer data', Journal of Sports Sciences, 38 399-404 (2020) [C1]

© 2019, © 2019 Informa UK Limited, trading as Taylor &amp; Francis Group. Detection of non-wear periods is an important step in accelerometer data processing. This study evaluat... [more]

© 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group. Detection of non-wear periods is an important step in accelerometer data processing. This study evaluated five non-wear detection algorithms for wrist accelerometer data and two rules for non-wear detection when non-wear and sleep algorithms are implemented in parallel. Non-wear algorithms were based on the standard deviation (SD), the high-pass filtered acceleration, or tilt angle. Rules for differentiating sleep from non-wear consisted of an override rule in which any overlap between non-wear and sleep was deemed non-wear; and a 75% rule in which non-wear periods were deemed sleep if the duration was < 75% of the sleep period. Non-wear algorithms were evaluated in 47 children who wore an ActiGraph GT3X+ accelerometer during school hours for 5¿days. Rules for differentiating sleep from non-wear were evaluated in 15 adults who wore a GeneActiv Original accelerometer continuously for 24¿hours. Classification accuracy for the non-wear algorithms ranged between 0.86¿0.95, with the SD of the vector magnitude providing the best performance. The override rule misclassified 37.1¿minutes of sleep as non-wear, while the 75% rule resulted in no misclassification. Non-wear algorithms based on the SD of the acceleration signal can effectively detect non-wear periods, while application of the 75% rule can effectively differentiate sleep from non-wear when examined concurrently.

DOI 10.1080/02640414.2019.1703301
Co-authors Nicole Nathan, Luke Wolfenden
2020 Yoong SL, Bolsewicz K, Grady A, Wyse R, Sutherland R, Hodder RK, et al., 'Adaptation of public health initiatives: expert views on current guidance and opportunities to advance their application and benefit.', Health Educ Res, 35 243-257 (2020)
DOI 10.1093/her/cyaa014
Co-authors Alice Grady, Nicole Nathan, Rebecca Wyse, Alix Hall, John Wiggers, Luke Wolfenden, Rebecca Hodder, John Attia, Serene Yoong, Sam Mccrabb
2019 Direito A, Murphy JJ, McLaughlin M, Mair J, Mackenzie K, Kamada M, et al., 'Early career professionals (researchers, practitioners, and policymakers) role in advocating, disseminating, and implementing the global action plan on physical activity: ISPAH early career network view', Journal of Physical Activity and Health, 16 940-944 (2019) [C1]

© 2019 Human Kinetics, Inc. Increasing population levels of physical activity (PA) can assist in achieving the United Nations sustainable development goals, benefiting multiple se... [more]

© 2019 Human Kinetics, Inc. Increasing population levels of physical activity (PA) can assist in achieving the United Nations sustainable development goals, benefiting multiple sectors and contributing to global prosperity. Practices and policies to increase PA levels exist at the subnational, national, and international levels. In 2018, the World Health Organization launched the first Global Action Plan on Physical Activity (GAPPA). The GAPPA provides guidance through a framework of effective and feasible policy actions for increasing PA, and requires engagement and advocacy from a wide spectrum of stakeholders for successful implementation of the proposed actions. Early career professionals, including researchers, practitioners, and policymakers, can play a major role with helping ¿all people being regularly active¿ by contributing to 4 overarching areas: (1) generation¿of evidence, (2) dissemination¿of key messages and evidence, (3) implementation¿of the evidence-based actions proposed in the GAPPA, and (4) contributing to advocacy for robust national action plans on PA. The contribution of early career professionals can be achieved through 5 pathways: (1) research, (2) workplace/practice, (3) business, (4) policy, and (5) professional and public opinion. Recommendations of how early career professionals can contribute to the generation, dissemination, and implementation of the evidence and actions proposed by the GAPPA are provided.

DOI 10.1123/jpah.2019-0450
Co-authors Matthew Mclaughlin Mc
2019 Hodder RK, O'Brien KM, Stacey FG, Tzelepis F, Wyse RJ, Bartlem KM, et al., 'Interventions for increasing fruit and vegetable consumption in children aged five years and under', Cochrane Database of Systematic Reviews, 2019 (2019) [C1]
DOI 10.1002/14651858.CD008552.pub6
Citations Scopus - 5Web of Science - 2
Co-authors Luke Wolfenden, Rebecca Hodder, Erica James, Rebecca Wyse, Flora Tzelepis, Kate Bartlem
2019 Pond N, Finch M, Sutherland R, Wolfenden L, Nathan N, Kingsland M, et al., 'Cluster randomised controlled trial of an m-health intervention in centre-based childcare services to reduce the packing of discretionary foods in children's lunchboxes: study protocol for the ' SWAP IT Childcare' trial', BMJ OPEN, 9 (2019)
DOI 10.1136/bmjopen-2018-026829
Citations Scopus - 1Web of Science - 2
Co-authors Luke Wolfenden, Nicole Nathan, Alice Grady, Serene Yoong
2019 Sutherland R, Campbell E, Nathan N, Wolfenden L, Lubans DR, Morgan PJ, et al., 'A cluster randomised trial of an intervention to increase the implementation of physical activity practices in secondary schools: study protocol for scaling up the Physical Activity 4 Everyone (PA4E1) program', BMC PUBLIC HEALTH, 19 (2019)
DOI 10.1186/s12889-019-6965-0
Citations Scopus - 2Web of Science - 3
Co-authors Philip Morgan, Christopher Oldmeadow, Matthew Mclaughlin Mc, David Lubans, Nicole Nathan, Luke Wolfenden, Andrew Searles, John Wiggers
2019 Nathan N, Janssen L, Sutherland R, Hodder RK, Evans CEL, Booth D, et al., 'The effectiveness of lunchbox interventions on improving the foods and beverages packed and consumed by children at centre-based care or school: a systematic review and meta-analysis', INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY, 16 (2019) [C1]
DOI 10.1186/s12966-019-0798-1
Citations Scopus - 12Web of Science - 10
Co-authors Serene Yoong, Nicole Nathan, Luke Wolfenden, Rebecca Hodder, Kathryn L Reilly
2019 McCrabb S, Lane C, Hall A, Milat A, Bauman A, Sutherland R, et al., 'Scaling-up evidence-based obesity interventions: A systematic review assessing intervention adaptations and effectiveness and quantifying the scale-up penalty', OBESITY REVIEWS, 20 964-982 (2019) [C1]
DOI 10.1111/obr.12845
Citations Scopus - 30Web of Science - 23
Co-authors Alix Hall, Serene Yoong, Luke Wolfenden, Sam Mccrabb
2019 McCarthy N, Nathan N, Hodder R, Lecathelinais C, Sutherland R, Campbell E, Wolfenden L, 'Australian primary school student's attitudes to changing from traditional school uniforms to sports uniforms and association with student characteristics', AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH, 43 94-95 (2019)
DOI 10.1111/1753-6405.12851
Co-authors Luke Wolfenden, Nicole Nathan, Rebecca Hodder
2019 Sutherland R, Brown A, Nathan N, Janssen L, Reynolds R, Walton A, et al., 'Protocol for an effectiveness- implementation hybrid trial to assess the effectiveness and cost-effectiveness of an m-health intervention to decrease the consumption of discretionary foods packed in school lunchboxes: the 'SWAP IT' trial', BMC PUBLIC HEALTH, 19 (2019)
DOI 10.1186/s12889-019-7725-x
Co-authors Andrew Searles, Christopher Oldmeadow, Serene Yoong, John Wiggers, Kathryn L Reilly, Luke Wolfenden, Nicole Nathan
2019 Reynolds R, Sutherland R, Nathan N, Janssen L, Lecathelinais C, Reilly K, et al., 'Feasibility and principal acceptability of school-based mobile communication applications to disseminate healthy lunchbox messages to parents', Health Promotion Journal of Australia, 30 108-113 (2019) [C1]

© 2018 Australian Health Promotion Association Issue addressed: This study aimed to assess the feasibility and acceptability of using an existing school-based mobile communication... [more]

© 2018 Australian Health Promotion Association Issue addressed: This study aimed to assess the feasibility and acceptability of using an existing school-based mobile communication application to deliver messages to parents on how to pack a healthy lunchbox. Methods: A telephone survey was conducted with 196 primary school principals within the Hunter New England region of New South Wales, Australia, in 2016. Results: Almost two thirds of primary schools (59%) currently use a school-based mobile communication application to communicate with parents. Most principals (91%) agreed school lunchboxes need improving, of which 80% agree it is a school's role to provide information and guidelines to parents. However, only 50% of principals reported currently providing such information. The provision of lunchbox messages to parents by a third party appeared an acceptable model of delivery by principals. Larger schools and schools in urban and lower socio-economic localities were more likely to have used a school-based mobile communication application. Conclusion: The majority of principals recognise student lunchboxes need improving. The use of school-based mobile communication applications appears to be feasible and acceptable by principals as a method of communicating lunchbox messages to parents. So what?: Use of school-based mobile communication applications may be an effective method for delivering health information at a population level. Future research should assess the potential efficacy of disseminating health interventions via this modality.

DOI 10.1002/hpja.57
Citations Scopus - 4Web of Science - 2
Co-authors Kathryn L Reilly, Nicole Nathan, Luke Wolfenden
2019 Delaney T, Sutherland R, Wyse R, Wolfenden L, Lecathelinais C, Janssen L, et al., 'A cross-sectional study of the nutritional quality of student canteen purchases from New South Wales primary-school canteens', Public Health Nutrition, 22 3092-3100 (2019) [C1]

© 2019 The Authors. Objective: To assess the nutritional quality of student canteen purchases at recess and lunch, including: (i) the mean energy (kilojoules), saturated fat (gram... [more]

© 2019 The Authors. Objective: To assess the nutritional quality of student canteen purchases at recess and lunch, including: (i) the mean energy (kilojoules), saturated fat (grams), total sugar (grams) and Na (milligrams) and percentage of energy from saturated fat and total sugar; and (ii) the proportion and types of foods purchased that are healthier (green) and less healthy (amber/red) according to a state school canteen policy.Design: A cross-sectional study of student canteen food and beverage recess and lunch purchases.Setting: Twenty-six randomly selected government primary schools that were non-compliant with a state school canteen policy from a region of New South Wales, Australia, were approached to participate.Participants: Students (aged 5-12 years) of participating schools.Results: Eighteen schools (69 %) consented to participate. On average students' recess purchases contained 571·2 kJ energy, 1·6 g saturated fat, 11·6 g total sugar and 132·4 mg Na with 10·0 % of energy from saturated fat and 37·8 % of energy from total sugar. Students' lunch purchases contained 685·4 kJ energy, 1·8 g saturated fat, 12·7 g total sugar and 151·4 mg Na with 9·5 % of energy from saturated fat and 31·8 % of energy from total sugar. Less healthy items represented 72 and 76 % of all items purchased at recess and lunch, respectively, with 'savoury snacks' and 'sugar-sweetened ice blocks and slushies' being the most common recess and lunch purchases, respectively.Conclusions: There is considerable scope to improve the nutritional quality of student purchases from primary-school canteens, with a high percentage of energy from total sugar. Future research is required to identify effective strategies to enhance compliance with canteen policies and support the purchase of healthier foods from school canteens.

DOI 10.1017/S1368980019001903
Co-authors Luke Wolfenden, John Wiggers, Kathryn L Reilly, Rebecca Wyse, Serene Yoong
2019 Nathan N, Wiggers J, Bauman AE, Rissel C, Searles A, Reeves P, et al., 'A cluster randomised controlled trial of an intervention to increase the implementation of school physical activity policies and guidelines: study protocol for the physically active children in education (PACE) study', BMC PUBLIC HEALTH, 19 (2019)
DOI 10.1186/s12889-019-6492-z
Citations Scopus - 5Web of Science - 6
Co-authors Luke Wolfenden, Andrew Searles, John Wiggers, Christopher Oldmeadow, Nicole Nathan, Kathryn L Reilly
2019 Sutherland R, Nathan N, Brown A, Yoong S, Finch M, Lecathelinais C, et al., 'A randomized controlled trial to assess the potential efficacy, feasibility and acceptability of an m-health intervention targeting parents of school aged children to improve the nutritional quality of foods packed in the lunchbox 'SWAP IT'', International Journal of Behavioral Nutrition and Physical Activity, 16 1-13 (2019) [C1]
DOI 10.1186/s12966-019-0812-7
Citations Scopus - 4Web of Science - 4
Co-authors Alix Hall, Serene Yoong, John Wiggers, Luke Wolfenden, Nicole Nathan
2019 Reilly K, Yoong SL, Sutherland R, Wiggers JH, Delaney T, Reynolds RC, et al., 'Secondary school implementation of a healthy eating policy', HEALTH PROMOTION JOURNAL OF AUSTRALIA, (2019)
DOI 10.1002/hpja.310
Co-authors Serene Yoong, Kathryn L Reilly, John Wiggers, Luke Wolfenden
2019 Wolfenden L, Nathan N, Reilly K, Delaney T, Janssen LM, Reynolds R, et al., 'Two-year follow-up of a randomised controlled trial to assess the sustainability of a school intervention to improve the implementation of a school-based nutrition policy', Health Promotion Journal of Australia, 30 26-33 (2019) [C1]

© 2019 Australian Health Promotion Association Issue addressed: School-based nutrition policies can have a positive effect on the school food environment. The primary aim of this ... [more]

© 2019 Australian Health Promotion Association Issue addressed: School-based nutrition policies can have a positive effect on the school food environment. The primary aim of this study was to assess the primary school adherence to a mandatory state-wide healthy canteen policy 12¿months after an effective multi-strategic implementation intervention concluded. Methods: Primary schools were randomised to (a) a 12-14¿months multi-strategic intervention or (b) no-intervention (control). The intervention aimed to improve implementation of a state-wide canteen policy by encouraging schools to remove unhealthy food and beverages (classified as ¿¿red¿¿ or ¿¿banned¿¿) from canteen menus and replace with healthy items (classified as ¿¿green¿¿). No implementation support was provided to either group by the research team between the 12 and 24¿months data collection period. Results: Seventy schools participated, of which 56 schools were assessed at 24-month follow-up. Intervention schools were less likely to have a menu which contained ¿¿red/banned¿¿ items at 24-month follow-up (RR¿=¿2.28; 95% CI: 1.18-4.40; P¿=¿0.01). Intervention schools, however, were not more likely than controls to have a menu which contained >50% ¿¿green¿¿ items at 24-month follow-up (RR¿=¿1.29; 95% CI: 0.98-1.70; P¿=¿0.10). Intervention schools were more likely to adhere to both policy components (no red/banned items and >50% green items on the menu) than control schools (RR¿=¿2.61; 95% CI: 1.29-5.29; P¿=¿0.006). Among intervention schools that were fully adherent to the policy following implementation support (12-month post baseline), all were also adherent at the 24-month follow-up. Conclusion: The intervention was effective in achieving long-term school adherence to a state-wide canteen policy at 24-month follow-up. So what?: The findings suggest that sustained improvements in implementation of school nutrition policies is possible following a period (12¿months) of comprehensive implementation support.

DOI 10.1002/hpja.238
Citations Scopus - 1Web of Science - 1
Co-authors Kathryn L Reilly, Nicole Nathan, Jenna Hollis, Luke Wolfenden, Christopher M Williams, John Wiggers, Rebecca Wyse, Serene Yoong
2019 Wolfenden L, Jones J, Parmenter B, Razak LA, Wiggers J, Morgan PJ, et al., 'Efficacy of a free-play intervention to increase physical activity during childcare: A randomized controlled trial', Health Education Research, 34 98-112 (2019) [C1]

© ° The Author(s) 2018. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com. The primary aim of this study was t... [more]

© ° The Author(s) 2018. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com. The primary aim of this study was to assess the efficacy of a childcare-based intervention in increasing child physical activity by allowing children unrestricted access to outdoor areas for free-play when structured activity is not taking place. A randomized controlled trial was conducted in six childcare services. Intervention services provided children unrestricted access outdoors for active free-play, while control services provided their usual scheduled periods of outdoor play. Consent was obtained from 231 children. Child moderate to vigorous activity (MVPA), the primary trial outcome, was assessed via accelerometer at baseline and 3 months post baseline. Intervention effects were examined using Generalised Linear Mixed Models. Controlling for child age, gender and baseline outcome measure, at follow-up there were no significant differences between groups in minutes of MVPA in-care (mean difference: 4.85; 95% CI: -3.96, 13.66; P = 0.28), proportion of wear time in-care spent in MVPA (mean difference: 1.52%; 95% CI: -0.50, 3.53; P = 0.14) or total physical activity in-care (mean difference in counts per minute: 23.18; 95% CI: -4.26, 50.61; P = 0.10), nor on measures of child cognition (P = 0.45-0.91). It was concluded that interventions addressing multiple aspects of the childcare and home environment might provide the greatest potential to improve child physical activity.

DOI 10.1093/her/cyy041
Citations Scopus - 4Web of Science - 2
Co-authors Philip Morgan, Tara Clinton-Mcharg, Luke Wolfenden, Serene Yoong, John Wiggers
2019 Wyse R, Delaney T, Gibbins P, Ball K, Campbell K, Yoong SL, et al., 'Cluster randomised controlled trial of an online intervention to improve healthy food purchases from primary school canteens: a study protocol of the 'click & crunch' trial', BMJ OPEN, 9 (2019)
DOI 10.1136/bmjopen-2019-030538
Citations Scopus - 1Web of Science - 1
Co-authors Rebecca Wyse, Kathryn L Reilly, Christopher Oldmeadow, Serene Yoong, John Attia, Nicole Nathan, John Wiggers, Luke Wolfenden
2019 Wolfenden L, Reilly K, Kingsland M, Grady A, Williams CM, Nathan N, et al., 'Identifying opportunities to develop the science of implementation for community-based non-communicable disease prevention: A review of implementation trials', Preventive Medicine, 118 279-285 (2019) [C1]

© 2018 Implementation of interventions in community organisations such as schools, childcare centres, and sporting clubs are recommended to target a range of modifiable risks of n... [more]

© 2018 Implementation of interventions in community organisations such as schools, childcare centres, and sporting clubs are recommended to target a range of modifiable risks of non-communicable diseases. Poor implementation, however, is common and has contributed to the failure of non-communicable disease interventions globally. This study aimed to characterise experimental research regarding strategies to improve implementation of chronic disease prevention programs in community settings. The review used data collected in three comprehensive systematic reviews undertaken between August 2015 and July 2017. Randomised controlled trials, including cluster design, and non-randomised trials with a parallel control group were included. The data were extracted to describe trial characteristics, implementation strategies employed, implementation outcomes and study quality. Of the 40 implementation trials included in the study, unhealthy diet was the most common risk factor targeted (n = 20). The most commonly reported implementation strategies were educational meetings (n = 38, 95%), educational materials (n = 36, 90%) and educational outreach visits (n = 29, 73%). Few trials were conducted ¿at-scale¿ (n = 8, 20%) or reported adverse effects (n = 5, 13%). The reporting of implementation related outcomes; intervention adoption (n = 13, 33%); appropriateness (n = 11, 28%); acceptability (n = 8, 20%); feasibility (n = 8, 20%); cost (n = 3, 8%); and sustainability (n = 2, 5%); was limited. For the majority of trials, risk of bias was high for blinding of study personnel/participants and outcome assessors. Testing of strategies to improve implementation of non-communicable disease prevention strategies in community settings, delivered ¿at-scale¿, utilising implementation frameworks, including a comprehensive range of implementation outcomes should be priority areas for future research in implementation science.

DOI 10.1016/j.ypmed.2018.11.014
Citations Scopus - 8Web of Science - 8
Co-authors Serene Yoong, Nicole Nathan, Alice Grady, Luke Wolfenden, Christopher M Williams, John Wiggers, Rebecca Hodder, Kathryn L Reilly
2019 Yoong SL, Nathan N, Reilly K, Sutherland R, Straus S, Barnes C, et al., 'Adapting implementation strategies: a case study of how to support implementation of healthy canteen policies', Public Health, 177 19-25 (2019) [C1]

© 2019 The Royal Society for Public Health Objectives: Although evidence-based interventions (EBIs) and effective strategies to implement them exist, they cannot be used by policy... [more]

© 2019 The Royal Society for Public Health Objectives: Although evidence-based interventions (EBIs) and effective strategies to implement them exist, they cannot be used by policy makers and practitioners if they do not align with end users¿ needs. As such, adaptations to EBIs and implementation approaches are likely to occur to increase ¿fit¿ with end users¿ capacity. This article describes an approach undertaken by a population health service delivery unit in one Australian state to develop an adapted implementation strategy to support the implementation of the mandatory healthy canteen policy (EBI) to all schools located in the service delivery region. Study design: This is a case study of adapting an intervention to improve implementation of the healthy canteen policy. Methods and results: This is a six-step pragmatic, empirically driven approach. The steps include (i) adapt, where appropriate, the EBI to facilitate implementation; (ii) identify end users¿ capacity for implementation; (iii) identify opportunities to adapt the implementation interventions while preserving meaningful intervention impact; (iv) undertake program adaptation; (v) develop training and resources to support delivery of implementation strategies and; (vi) evaluate the adapted intervention. This article describes the application of these steps by the authors to develop an adapted support strategy consistent with end users¿ needs. Conclusions: This study provides some guidance on how to adapt implementation support approaches particularly when EBIs cannot be adapted. Future empirical research providing guidance on making practical adaptation decisions are needed.

DOI 10.1016/j.puhe.2019.07.003
Co-authors Serene Yoong, Nicole Nathan, Kathryn L Reilly, Alice Grady, Luke Wolfenden
2019 Wolfenden L, Bolsewicz K, Grady A, McCrabb S, Kingsland M, Wiggers J, et al., 'Optimisation: Defining and exploring a concept to enhance the impact of public health initiatives', Health Research Policy and Systems, 17 (2019) [C1]
DOI 10.1186/s12961-019-0502-6
Citations Scopus - 2Web of Science - 2
Co-authors John Attia, Alix Hall, Serene Yoong, Rebecca Wyse, Nicole Nathan, Rebecca Hodder, John Wiggers, Sam Mccrabb, Alice Grady, Luke Wolfenden
2018 Hodder RK, Stacey FG, O'Brien KM, Wyse RJ, Clinton-McHarg T, Tzelepis F, et al., 'Interventions for increasing fruit and vegetable consumption in children aged five years and under', COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (2018)
DOI 10.1002/14651858.CD008552.pub4
Citations Scopus - 28Web of Science - 7
Co-authors Tara Clinton-Mcharg, Nicole Nathan, Rebecca Hodder, Rebecca Wyse, Flora Tzelepis, Kate Bartlem
2018 Abdul Razak L, Yoong SL, Wiggers J, Morgan P, Jones J, Finch M, et al., 'Impact of scheduling multiple free-play periods in childcare on child moderate-to-vigorous physical activity: a cluster randomised trial', International Journal of Behavioral Nutrition and Physical Activity, 15 1-13 (2018) [C1]
DOI 10.1186/s12966-018-0665-5
Citations Scopus - 18Web of Science - 16
Co-authors Luke Wolfenden, Serene Yoong, Philip Morgan, Tara Clinton-Mcharg, John Wiggers
2018 Nathan N, Elton B, Babic M, McCarthy N, Sutherland R, Presseau J, et al., 'Barriers and facilitators to the implementation of physical activity policies in schools: A systematic review', Preventive Medicine, 107 45-53 (2018) [C1]
DOI 10.1016/j.ypmed.2017.11.012
Citations Scopus - 25Web of Science - 24
Co-authors Serene Yoong, Nicole Nathan, Luke Wolfenden, Rebecca Hodder
2018 Ooi JY, Sutherland R, Nathan N, Yoong SL, Janssen L, Wrigley J, Wolfenden L, 'A cluster randomised controlled trial of a sugar-sweetened beverage intervention in secondary schools: Pilot study protocol', Nutrition and Health, 24 217-229 (2018)

© The Author(s) 2018. Background: Due to the rising prevalence of overweight and obesity in children and adolescents, reducing childhood overweight and obesity rates is a public-h... [more]

© The Author(s) 2018. Background: Due to the rising prevalence of overweight and obesity in children and adolescents, reducing childhood overweight and obesity rates is a public-health priority. A significant source of excess sugar and energy in children¿s diets comes from sugar-sweetened beverages (SSB), with adolescents having the highest intake of all age groups. However, existing interventions targeting SSB intake in adolescents have multiple limitations. Schools have proven to be an appropriate setting for improving student health. Aim: To assess the effectiveness of a school-based SSB intervention in reducing daily SSB consumption and daily percentage energy from SSBs of secondary-school students. Methods: A pilot study (switchURsip) was designed based on the Health Promoting Schools framework components. A convenience sample of schools in New South Wales, Australia will be used to recruit six schools (three intervention; three control). The study incorporates strategies that focus on factors associated with SSB intake in adolescents. These strategies include: lesson plans on SSB; communication with students and parents; school challenge to build peer support; and school nutrition environment modifications. Support strategies to facilitate implementation are executive leadership and school committees, auditing and feedback, providing resources, staff professional learning and communication and marketing. Conclusion: The high intake of SSB in adolescents has been consistently linked to having overweight and obesity, hence, interventions in this area should be prioritised. This pilot study intends to address identified evidence gaps by piloting the first intervention in Australia of its kind to reduce SSB intake in adolescents.

DOI 10.1177/0260106018791856
Citations Scopus - 3
Co-authors Nicole Nathan, Luke Wolfenden, Serene Yoong
2018 Hodder RK, O'Brien KM, Stacey FG, Wyse RJ, Clinton-Mcharg T, Tzelepis F, et al., 'Interventions for increasing fruit and vegetable consumption in children aged five years and under', Cochrane Database of Systematic Reviews, 2018 (2018)
DOI 10.1002/14651858.CD008552.pub5
Citations Scopus - 13Web of Science - 9
Co-authors Serene Yoong, Nicole Nathan, Flora Tzelepis, Rebecca Hodder, Rebecca Wyse, Luke Wolfenden, Kate Bartlem, Tara Clinton-Mcharg, Erica James
2018 Grady A, Yoong S, Sutherland R, Lee H, Nathan N, Wolfenden L, 'Improving the public health impact of eHealth and mHealth interventions', AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH, 42 118-119 (2018)
DOI 10.1111/1753-6405.12771
Citations Scopus - 11Web of Science - 10
Co-authors Nicole Nathan, Alice Grady, Luke Wolfenden, Serene Yoong
2018 Reilly K, Nathan N, Wu JHY, Delaney T, Wyse R, Cobcroft M, et al., 'Assessing the potential impact of a front-of-pack nutritional rating system on food availability in school canteens: A randomised controlled trial', Appetite, 121 309-315 (2018) [C1]

© 2017 Background Front-of-pack graphical nutritional rating of products is becoming an important strategy in many countries to improve healthy food purchases by consumers. Eviden... [more]

© 2017 Background Front-of-pack graphical nutritional rating of products is becoming an important strategy in many countries to improve healthy food purchases by consumers. Evidence of the effectiveness of such on facilitating healthy food choices by school food service providers has not been reported. The primary aim of the study was to assess the impact of providing front-of-pack nutritional rating information on school canteen managers¿ likely food selections. Secondary outcomes were canteen manager awareness, attitudes and reported barriers to using the front-of-pack information. Methods A randomised controlled trial involving primary school canteen managers was conducted in a single region in New South Wales, Australia. Eligible participants were randomised to an intervention or control group and asked in a telephone interview which of 12 common food products sold in school canteens they would sell. Both groups received product name and brand information. The intervention group also received information regarding the nutritional rating of products. Results Canteen managers in the intervention group were significantly more likely than those in the control group to indicate they would sell three of the six ¿healthier¿ products (p = 0.036, 0.005, 0.009). There was no difference between groups in the likelihood of making available for sale any of the six ¿less healthy¿ products. The majority of canteen managers who had heard of a product nutritional rating system agreed that it was helpful in identifying ¿healthier¿ foods (88%, n = 31). Conclusions The inclusion of product nutritional rating information has the potential to improve the availability of some ¿healthier¿ items on canteen menus and contribute to improving child dietary intake. Further research is required to determine whether the use of product nutritional rating information actually makes a difference to canteen manager choices.

DOI 10.1016/j.appet.2017.11.103
Co-authors Kathryn L Reilly, Serene Yoong, Rebecca Wyse, John Wiggers, Luke Wolfenden, Nicole Nathan
2017 Wolfenden L, Nathan NK, Sutherland R, Yoong SL, Hodder RK, Wyse RJ, et al., 'Strategies for enhancing the implementation of school-based policies or practices targeting risk factors for chronic disease', COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (2017) [C1]
DOI 10.1002/14651858.CD011677.pub2
Citations Scopus - 8Web of Science - 27
Co-authors Serene Yoong, Flora Tzelepis, Nicole Nathan, Alice Grady, Alison A Fielding, Rebecca Wyse, Rebecca Hodder, John Wiggers, Tara Clinton-Mcharg, Christopher M Williams, Luke Wolfenden
2017 Delaney T, Wyse R, Yoong SL, Sutherland R, Wiggers J, Ball K, et al., 'Cluster randomized controlled trial of a consumer behavior intervention to improve healthy food purchases from online canteens.', The American journal of clinical nutrition, 106 1311-1320 (2017) [C1]
DOI 10.3945/ajcn.117.158329
Citations Scopus - 7Web of Science - 7
Co-authors Rebecca Wyse, Serene Yoong, John Wiggers, Luke Wolfenden
2017 Delaney T, Wyse R, Yoong SL, Sutherland R, Wiggers J, Ball K, et al., 'Cluster randomised controlled trial of a consumer behaviour intervention to improve healthy food purchases from online canteens: study protocol', BMJ OPEN, 7 (2017)
DOI 10.1136/bmjopen-2016-014569
Citations Scopus - 8Web of Science - 8
Co-authors Serene Yoong, Luke Wolfenden, John Wiggers, Rebecca Wyse
2017 Hodder RK, Stacey FG, Wyse RJ, O'Brien KM, Clinton-McHarg T, Tzelepis F, et al., 'Interventions for increasing fruit and vegetable consumption in children aged five years and under', COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (2017) [C1]
DOI 10.1002/14651858.CD008552.pub3
Citations Scopus - 21Web of Science - 18
Co-authors Serene Yoong, Flora Tzelepis, Rebecca Wyse, Erica James, Tara Clinton-Mcharg, Kate Bartlem, Luke Wolfenden, Nicole Nathan, Rebecca Hodder
2017 Stacey FG, Finch M, Wolfenden L, Grady A, Jessop K, Wedesweiler T, et al., 'Evidence of the Potential Effectiveness of Centre-Based Childcare Policies and Practices on Child Diet and Physical Activity: Consolidating Evidence from Systematic Reviews of Intervention Trials and Observational Studies', Current Nutrition Reports, 6 228-246 (2017) [C1]
DOI 10.1007/s13668-017-0212-z
Citations Scopus - 11
Co-authors Serene Yoong, Luke Wolfenden, Kate Bartlem, Alice Grady
2017 Sutherland RL, Nathan NK, Lubans DR, Cohen K, Davies LJ, Desmet C, et al., 'An RCT to Facilitate Implementation of School Practices Known to Increase Physical Activity.', American journal of preventive medicine, 53 818-828 (2017) [C1]
DOI 10.1016/j.amepre.2017.08.009
Citations Scopus - 7Web of Science - 6
Co-authors John Wiggers, David Lubans, Nicole Nathan, Luke Wolfenden
2017 Nathan N, Sutherland R, Beauchamp MR, Cohen K, Hulteen RM, Babic M, et al., 'Feasibility and efficacy of the Great Leaders Active StudentS (GLASS) program on children's physical activity and object control skill competency: A non-randomised trial', Journal of Science and Medicine in Sport, 20 1081-1086 (2017) [C1]
DOI 10.1016/j.jsams.2017.04.016
Citations Scopus - 4Web of Science - 8
Co-authors Nicole Nathan, Luke Wolfenden, David Lubans
2017 Nathan N, Wiggers J, Wyse R, Williams CM, Sutherland R, Yoong SL, et al., 'Factors associated with the implementation of a vegetable and fruit program in a population of Australian elementary schools', Health Education Research, 32 197-205 (2017) [C1]
DOI 10.1093/her/cyx038
Citations Scopus - 1Web of Science - 2
Co-authors Christopher M Williams, Luke Wolfenden, Nicole Nathan, John Wiggers, Serene Yoong, Rebecca Wyse
2017 Wyse R, Yoong SL, Dodds P, Campbell L, Delaney T, Nathan N, et al., 'Online canteens: Awareness, use, barriers to use, and the acceptability of potential online strategies to improve public health nutrition in primary schools', Health Promotion Journal of Australia, 28 67-71 (2017) [C1]

© Australian Health Promotion Association 2017. Issue addressed: This study of primary school principals assessed the awareness, use, barriers to use and acceptability of online c... [more]

© Australian Health Promotion Association 2017. Issue addressed: This study of primary school principals assessed the awareness, use, barriers to use and acceptability of online canteens. Methods: A telephone survey of 123 primary school principals within the Hunter New England Region of New South Wales, Australia was conducted from September 2014 to November 2014. Results: Fifty-six percent of principals were aware of the existence of online canteens, with 8% having implemented such a system, and 38% likely to do so in the future. Medium/large schools were more likely to be aware of or to use online canteens, however there were no differences in awareness or use in relation to school rurality or socioeconomic advantage. Principals cited parent internet access as the most commonly identified perceived barrier to online canteen use, and the majority of principals (71-93%) agreed that it would be acceptable to implement a range of consumer behaviour strategies via an online canteen. Conclusions: Study findings suggest that despite relatively low levels of current use, online canteens have the potential to reach a large proportion of school communities in the future, across geographical and socioeconomic divides, and that the nutrition interventions which they have the capacity to deliver are considered acceptable to school principals. So what? Online canteens may represent an opportunity to deliver nutrition interventions to school communities. Future research should examine the feasibility and potential effectiveness of interventions delivered via this modality.

DOI 10.1071/HE15095
Citations Scopus - 7Web of Science - 6
Co-authors Kathryn L Reilly, Serene Yoong, Rebecca Wyse, Luke Wolfenden, Nicole Nathan, John Wiggers
2017 Borde R, Smith JJ, Sutherland R, Nathan N, Lubans DR, 'Methodological considerations and impact of school-based interventions on objectively measured physical activity in adolescents: a systematic review and meta-analysis', Obesity Reviews, 18 476-490 (2017) [C1]

© 2017 World Obesity Federation Objective: The aims of this systematic review and meta-analysis are (i) to determine the impact of school-based interventions on objectively measur... [more]

© 2017 World Obesity Federation Objective: The aims of this systematic review and meta-analysis are (i) to determine the impact of school-based interventions on objectively measured physical activity among adolescents and (ii) to examine accelerometer methods and decision rule reporting in previous interventions. Methods: A systematic search was performed to identify randomized controlled trials targeting adolescents (age: =10¿years), conducted in the school setting, and reporting objectively measured physical activity. Random effects meta-analyses were conducted to determine the pooled effects of previous interventions on total and moderate-to-vigorous physical activity. Potential moderators of intervention effects were also explored. Results: Thirteen articles met the inclusion criteria, and twelve were included in the meta-analysis. The pooled effects were small and non-significant for both total physical activity (standardized mean difference¿=¿0.02 [95% confidence interval¿=¿-0.13 to 0.18]) and moderate-to-vigorous physical activity (standardized mean difference¿=¿0.24 [95% confidence interval¿=¿-0.08 to 0.56]). Sample age and accelerometer compliance were significant moderators for total physical activity, with a younger sample and higher compliance associated with larger effects. Conclusion: Previous school-based physical activity interventions targeting adolescents have been largely unsuccessful, particularly for older adolescents. There is a need for more high-quality research using objective monitoring in this population. Future interventions should comply with best-practice recommendations regarding physical activity monitoring protocols.

DOI 10.1111/obr.12517
Citations Scopus - 47Web of Science - 51
Co-authors Jordan Smith, Nicole Nathan, David Lubans
2017 Hollis JL, Sutherland R, Williams AJ, Campbell E, Nathan N, Wolfenden L, et al., 'A systematic review and meta-analysis of moderate-to-vigorous physical activity levels in secondary school physical education lessons', International Journal of Behavioral Nutrition and Physical Activity, 14 (2017) [C1]

© 2017 The Author(s). Background: Schools play an important role in physical activity promotion for adolescents. The systematic review aimed to determine the proportion of seconda... [more]

© 2017 The Author(s). Background: Schools play an important role in physical activity promotion for adolescents. The systematic review aimed to determine the proportion of secondary (middle and high) school physical education (PE) lesson time that students spend in moderate to vigorous physical activity (MVPA), and to assess if MVPA was moderated by school level (middle and high school), type of physical activity measurement and type of PE activities. Methods: A systematic search of nine electronic databases was conducted (PROSPERO2014:CRD42014009649). Studies were eligible if they were published between 2005 and 2014; written in English; assessed MVPA in PE lessons of secondary (middle and high) school students; and used a quantitative MVPA measure (i.e., accelerometry, heart rate monitoring, pedometers or observational measures). Two reviewers examined the retrieved articles, assessed risk of bias, and performed data extraction. Random effects meta-analysis was used to calculate a pooled estimate of the percent of PE lesson time spent in MVPA and to assess moderator effects where data allowed. Results: The search yielded 5,132 potentially relevant articles; 28 articles representing 25 studies (7 middle and 18 high school) from seven countries were included. Twelve studies measured MVPA through observational measures, seven used accelerometers, five used heart rate monitors and four used pedometers (including three studies using a mix of measures). Meta-analysis of 15 studies found that overall, students spent a mean (95% CI) of 40.5% (34.8-46.2%) of PE in MVPA. Middle school students spent 48.6% (41.3-55.9%) of the lesson in MVPA (n=5 studies) and high school students 35.9% (28.3-43.6%) (n=10 studies). Studies measuring MVPA using accelerometers (n=5) showed that students spent 34.7% (25.1-44.4%) of the lesson in MVPA, while 44.4% (38.3-50.5%) was found for lessons assessed via observation (n=9), 43.1% (24.3-61.9%) of the lesson for a heart rate based study, and 35.9% (31.0-40.8%) for a pedometer-measured study. Conclusions: The proportion of PE spent in MVPA (40.5%) is below the US Centre for Disease Control and Prevention and the UK Associations for Physical Education recommendation of 50%. Findings differed according to the method of MVPA assessment. Additional strategies and intervention research are needed to build more active lesson time in PE.

DOI 10.1186/s12966-017-0504-0
Citations Scopus - 47Web of Science - 44
Co-authors Nicole Nathan, Philip Morgan, Jenna Hollis, Luke Wolfenden, David Lubans, John Wiggers
2017 Wolfenden L, Nathan N, Janssen LM, Wiggers J, Reilly K, Delaney T, et al., 'Multi-strategic intervention to enhance implementation of healthy canteen policy: a randomised controlled trial', IMPLEMENTATION SCIENCE, 12 (2017) [C1]
DOI 10.1186/s13012-016-0537-9
Citations Scopus - 34Web of Science - 34
Co-authors Nicole Nathan, Kathryn L Reilly, Serene Yoong, Christopher Oldmeadow, Rebecca Wyse, John Wiggers, Megan Freund, Christopher M Williams, Luke Wolfenden
2016 Nathan N, Yoong SL, Sutherland R, Reilly K, Delaney T, Janssen L, et al., 'Effectiveness of a multicomponent intervention to enhance implementation of a healthy canteen policy in Australian primary schools: a randomised controlled trial', INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY, 13 (2016) [C1]
DOI 10.1186/s12966-016-0431-5
Citations Scopus - 25Web of Science - 22
Co-authors Serene Yoong, John Wiggers, Luke Wolfenden, Nicole Nathan, Kathryn L Reilly
2016 Sutherland RL, Campbell EM, Lubans DR, Morgan PJ, Nathan NK, Wolfenden L, et al., 'The Physical Activity 4 Everyone Cluster Randomized Trial: 2-Year Outcomes of a School Physical Activity Intervention Among Adolescents.', Am J Prev Med, 51 195-205 (2016) [C1]
DOI 10.1016/j.amepre.2016.02.020
Citations Scopus - 34Web of Science - 30
Co-authors Nicole Nathan, Jenna Hollis, Luke Wolfenden, David Lubans, John Wiggers, Christopher Oldmeadow, Philip Morgan
2016 Hollis JL, Williams AJ, Sutherland R, Campbell E, Nathan N, Wolfenden L, et al., 'A systematic review and meta-analysis of moderate-to-vigorous physical activity levels in elementary school physical education lessons', Preventive Medicine, 86 34-54 (2016) [C1]

© 2015 Elsevier Inc. Objective: To examine elementary school students&apos; moderate-to-vigorous physical activity (MVPA) levels during physical education (PE) lessons. Methods: A... [more]

© 2015 Elsevier Inc. Objective: To examine elementary school students' moderate-to-vigorous physical activity (MVPA) levels during physical education (PE) lessons. Methods: A systematic search of nine electronic databases was conducted (PROSPERO2014:CRD42014009649). Studies were eligible if they were in English; published between 2005-April 2014; assessed MVPA levels in PE lessons of elementary school children (aged four-12 years); and used an objective MVPA measure. Two reviewers retrieved articles, assessed risk of bias, and performed data extraction. The findings were synthesised using a meta-analysis. Results: The search yielded 5132 articles. Thirteen studies from nine countries met the inclusion criteria. Eight studies measured MVPA through observational measures, five used accelerometry and one used heart rate monitoring. The percentage of PE lesson time spent in MVPA ranged between 11.4-88.5%. Meta-analysis of seven studies (direct observations; 4 accelerometers) found that children spent a mean (95% CI) 44.8 (28.2-61.4)% of PE lesson time in MVPA. When measured using direct observation and accelerometers, children spent 57.6 (47.3-68.2) and 32.6 (5.9-59.3)% of PE lesson time in MVPA, respectively. The review has limitations; the search strategy was restricted to studies in English; theses, dissertations and conference abstracts were excluded; and six studies that provided insufficient data were excluded from the meta-analysis. Conclusion: MVPA levels during elementary school PE lessons do not meet the United States Centre for Disease Control and Prevention and the United Kingdom's Association of Physical Education recommendation (50% of lesson time), but is higher than estimated in the previous review (34.2%). Interventions to increase MVPA in PE lessons are needed.

DOI 10.1016/j.ypmed.2015.11.018
Citations Scopus - 83Web of Science - 76
Co-authors Luke Wolfenden, Philip Morgan, Nicole Nathan, Jenna Hollis, David Lubans, John Wiggers
2016 Yoong SL, Nathan N, Wolfenden L, Wiggers J, Reilly K, Oldmeadow C, et al., 'CAFE: a multicomponent audit and feedback intervention to improve implementation of healthy food policy in primary school canteens: a randomised controlled trial', INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY, 13 (2016) [C1]
DOI 10.1186/s12966-016-0453-z
Citations Scopus - 19Web of Science - 15
Co-authors Kathryn L Reilly, Nicole Nathan, Christopher Oldmeadow, Serene Yoong, Rebecca Wyse, Christopher M Williams, Luke Wolfenden, John Wiggers
2016 Sutherland R, Reeves P, Campbell E, Lubans DR, Morgan PJ, Nathan N, et al., 'Cost effectiveness of a multi-component school-based physical activity intervention targeting adolescents: The 'Physical Activity 4 Everyone' cluster randomized trial', International Journal of Behavioral Nutrition and Physical Activity, 13 (2016) [C1]

© 2016 The Author(s). Background: Few school-based interventions have been successful in reducing physical activity decline and preventing overweight and obesity in adolescent pop... [more]

© 2016 The Author(s). Background: Few school-based interventions have been successful in reducing physical activity decline and preventing overweight and obesity in adolescent populations. As a result, few cost effectiveness analyses have been reported. The aim of this paper is to report the cost and cost effectiveness of the Physical Activity 4 Everyone (PA4E1) intervention which was a multi-component intervention implemented in secondary schools located in low-income communities. Cost effectiveness was assessed using both the physical activity and weight status trial outcomes. Methods: Intervention and Study Design: The PA4E1 cluster randomised controlled trial was implemented in 10 Australian secondary schools (5 intervention: 5 control) and consisted of intervention schools receiving seven physical activity promotion strategies and six additional strategies that supported school implementation of the intervention components. Costs associated with physical activity strategies, and intervention implementation strategies within the five intervention schools were estimated and compared to the costs of usual physical activity practices of schools in the control group. The total cost of implementing the intervention was estimated from a societal perspective, based on the number of enrolled students in the target grade at the start of the intervention (Grade 7, n = 837). Economic Outcomes: The economic analysis outcomes were cost and incremental cost effectiveness ratios for the following: minutes of moderate-to-vigorous physical activity (MVPA) per day gained, MET hours gained per person/day; Body Mass Index (BMI) unit avoided; and 10 % reduction in BMI z-score. Results: The intervention cost AUD $329,952 over 24 months, or AUD$394 per student in the intervention group. This resulted in a cost effectiveness ratio of AUD$56 ($35-$147) per additional minute of MVPA, AUD$1 ($0.6-$2.7) per MET hour gained per person per day, AUD$1408 ($788-$6,570) per BMI unit avoided, and AUD$563 ($282-$3,942) per 10 % reduction in BMI z-score. Conclusion: PA4E1 is a cost effective intervention for increasing the physical activity levels and reducing unhealthy weight gain in adolescence, a period in which physical activity typically declines. Additional modelling could explore the potential economic impact of the intervention on morbidity and mortality. Trial registration: Australian New Zealand Clinical Trials Registry ACTRN12612000382875.

DOI 10.1186/s12966-016-0418-2
Citations Scopus - 17Web of Science - 19
Co-authors David Lubans, Luke Wolfenden, John Wiggers, Philip Morgan, Nicole Nathan
2016 Wolfenden L, Wiggers J, Morgan P, Abdul Razak L, Jones J, Finch M, et al., 'A randomised controlled trial of multiple periods of outdoor free-play to increase moderate-to-vigorous physical activity among 3 to 6 year old children attending childcare: study protocol', BMC Public Health, (2016)
DOI 10.1186/s12889-016-3604-x
Citations Scopus - 8Web of Science - 9
Co-authors John Wiggers, Luke Wolfenden, Serene Yoong, Philip Morgan
2016 Hollis JL, Sutherland R, Campbell L, Morgan PJ, Lubans DR, Nathan N, et al., 'Effects of a 'school-based' physical activity intervention on adiposity in adolescents from economically disadvantaged communities: secondary outcomes of the 'Physical Activity 4 Everyone' RCT', INTERNATIONAL JOURNAL OF OBESITY, 40 1486-1493 (2016) [C1]
DOI 10.1038/ijo.2016.107
Citations Scopus - 14Web of Science - 11
Co-authors Christopher Oldmeadow, John Wiggers, David Lubans, Luke Wolfenden, Jenna Hollis, Nicole Nathan, Philip Morgan
2016 Reilly K, Nathan N, Wolfenden L, Wiggers J, Sutherland R, Wyse R, Yoong SL, 'Validity of four measures in assessing school canteen menu compliance with state-based healthy canteen policy', Health Promotion Journal of Australia, 27 215-221 (2016) [C1]

© Australian Health Promotion Association 2016. Issue addressed In order to assess the impact of healthy school canteen policies on food availability for students, valid methods o... [more]

© Australian Health Promotion Association 2016. Issue addressed In order to assess the impact of healthy school canteen policies on food availability for students, valid methods of measuring compliance are needed that can be applied at scale. The aim of this study is to assess the validity and direct cost of four methods to assess policy compliance: 1) principal and 2) canteen manager self-report via a computer-assisted telephone interview; and 3) comprehensive and 4) quick menu audits by dietitians, compared with observations. Methods A cross-sectional study took place in the Hunter region of NSW, Australia, in a sample of 38 primary schools that had previously participated in a randomised controlled trial to improve healthy canteen policy compliance. Policy compliance was assessed using the four methods specified above. Percentage agreement, kappa, sensitivity and specificity compared with observations was calculated together with the direct time taken and costs of each method. Indirect costs (including set-up costs) for all measures have not been included. Results Agreement with observations was substantial for the quick menu audit (kappa=0.68), and moderate for the comprehensive menu audit (kappa=0.42). Principal and canteen manager self-report resulted in poor agreement and low specificity with the gold standard. The self-reported measures had the lowest cost, followed by the quick menu audit and lastly the comprehensive menu audit. Conclusion The quick menu audit represents a valid and potentially low-cost method of supporting policy implementation at scale. So what? This study demonstrates that a quick menu audit represents a valid measure of undertaking assessment of school canteen policy compliance at a population level.

DOI 10.1071/HE16053
Citations Scopus - 14Web of Science - 14
Co-authors Rebecca Wyse, Nicole Nathan, Luke Wolfenden, John Wiggers, Serene Yoong, Kathryn L Reilly
2016 Sutherland R, Campbell E, Lubans DR, Morgan PJ, Okely AD, Nathan N, et al., 'Physical education in secondary schools located in low-income communities: Physical activity levels, lesson context and teacher interaction', Journal of Science and Medicine in Sport, 19 135-141 (2016) [C1]

© 2014. Objectives: Physical education (PE) plays an important role in contributing to students&apos; physical activity (PA); however, moderate-to-vigorous PA (MVPA) within PE is ... [more]

© 2014. Objectives: Physical education (PE) plays an important role in contributing to students' physical activity (PA); however, moderate-to-vigorous PA (MVPA) within PE is lower than recommended. Little is known about the PA levels of students from disadvantaged schools within PE. This study aimed to describe: (i) the PA levels of students from disadvantaged secondary schools during PE lessons, (ii) the lesson context and teacher interactions occurring during PE, and (iii) the associations between teacher, school or PE lesson characteristics with student physical activity levels in PE. Design: Cross-sectional study of 100 Grade 7 PE lessons across 10 secondary schools. Methods: System for observing fitness instruction time (SOFIT) was used to assess student PA, lesson context, and teacher interaction. Teacher and school characteristics were collected via survey. Mean proportion of lesson time was used to describe PA, lesson context and teacher interaction. Associations between each outcome variable and each characteristic were examined using 2-sample t-tests, ANOVAs and linear regression. Results: Thirty-nine percent of PE lesson was spent in MVPA, and less than 10% spent in VA. Lessons in schools in urban areas included significantly more MVPA than rural areas (P = 0.04). Male teachers and more experienced teachers conducted lessons with significantly more VA than female and less experienced teachers (P = 0.04 and 0.02). MVPA was also higher in lessons conducted by more experienced teachers. Conclusions: PA during PE lessons within disadvantaged secondary schools is below international recommendations. Male teachers, more experienced teachers and schools in urban regions teach more active lessons.

DOI 10.1016/j.jsams.2014.12.003
Citations Scopus - 9Web of Science - 7
Co-authors John Wiggers, Philip Morgan, Nicole Nathan, David Lubans
2016 Sutherland R, Campbell E, Lubans DR, Morgan PJ, Okely AD, Nathan N, et al., ''Physical activity 4 everyone' school-based intervention to prevent decline in adolescent physical activity levels: 12 month (mid-intervention) report on a cluster randomised trial', British Journal of Sports Medicine, 50 488-495 (2016) [C1]

Background: Adolescence is a recognised period of physical activity decline, particularly among low-income communities. We report the 12-month (midpoint) effects of a 2-year multi... [more]

Background: Adolescence is a recognised period of physical activity decline, particularly among low-income communities. We report the 12-month (midpoint) effects of a 2-year multicomponent physical activity intervention implemented in disadvantaged secondary schools. Methods: A cluster randomised trial was undertaken in 10 secondary schools located in disadvantaged areas in New South Wales, Australia. Students in Grade 7 were recruited, with follow-up in Grade 8. The intervention was guided by socioecological theory and included seven physical activity strategies, and six implementation adoption strategies. The primary outcome was mean minutes of moderate-to-vigorous physical activity (MVPA) per day assessed using Actigraph GT3X accelerometers. Outcome data were analysed using repeated measures linear mixed models. Results: At baseline, 1150 (93%) students participated in the data collection (mean age 12 years, 48% boys) and 1050 (79%) students participated at 12-month follow-up. By the 12-month follow-up, the six implementation adoption strategies had been used to support schools to deliver four of the seven physical activity elements. There was a significant group-by-time interaction for mean minutes of MVPA per day in favour of the intervention group (adjusted difference between groups at follow-up=3.85 min, 95% CI (0.79 to 6.91), p=0.01), including significantly more vigorous physical activity (2.45 min, p=0.01), equating to 27 min more MVPA per week. Summary: At 12-month follow-up, the intervention had reduced the decline in physical activity among adolescents from disadvantaged schools. The intervention may assist students to meet physical activity guidelines.

DOI 10.1136/bjsports-2014-094523
Citations Scopus - 30Web of Science - 28
Co-authors David Lubans, Luke Wolfenden, Jenna Hollis, Nicole Nathan, John Wiggers, Philip Morgan
2015 Williams CM, Nathan NK, Wyse RJ, Yoong SL, Delaney T, Wiggers J, et al., 'Strategies for enhancing the implementation of school-based policies or practices targeting risk factors for chronic disease', Cochrane Database of Systematic Reviews, 2015 (2015)

© 2015 The Cochrane Collaboration. This is the protocol for a review and there is no abstract. The objectives are as follows: The primary aims of the review are to examine the eff... [more]

© 2015 The Cochrane Collaboration. This is the protocol for a review and there is no abstract. The objectives are as follows: The primary aims of the review are to examine the effectiveness of strategies aiming to improve the implementation of school-based policies, programs or practices that aim to promote healthy or reduce unhealthy behaviours relating to child diet, physical activity, obesity, or tobacco or alcohol use. Secondary objectives of the review are to: examine the effectiveness of implementation strategies on health behavioural (e.g. fruit and vegetable consumption) and anthropometric outcomes (e.g. BMI, weight); describe the impact of such strategies on the knowledge, skills or attitudes of stakeholders involved in implementing health promoting policies, programs or practices; describe the cost or cost effectiveness of such strategies; describe any unintended adverse effects of strategies on schools, school staff or children.

DOI 10.1002/14651858.CD011677
Citations Scopus - 33
Co-authors Rebecca Hodder, John Wiggers, Megan Freund, Christopher M Williams, Nicole Nathan, Serene Yoong, Rebecca Wyse, Luke Wolfenden
2015 Wolfenden L, Finch M, Nathan N, Weaver N, Wiggers J, Yoong SL, et al., 'Factors associated with early childhood education and care service implementation of healthy eating and physical activity policies and practices in Australia: a cross-sectional study', Translational Behavioral Medicine, 5 327-334 (2015) [C1]

© 2015, Society of Behavioral Medicine. Many early childhood education and care (ECEC) services fail to implement recommended policies and practices supportive of healthy eating a... [more]

© 2015, Society of Behavioral Medicine. Many early childhood education and care (ECEC) services fail to implement recommended policies and practices supportive of healthy eating and physical activity. The purpose of this study was to assess whether certain theoretically-based factors are associated with implementation of healthy eating and physical activity policies and practices in a sample of ECEC services. A cross-sectional survey was conducted with Service Managers of ECEC services. The survey assessed the operational characteristics, policy, and practice implementation, and 13 factors were suggested by Damschroder¿s Consolidated Framework for Implementation Research to impede or promote implementation. Logistic regression analyses found a significant association between implementation factor score and full implementation (OR 1.38; 95% CI 1.18¿1.61; p = <0.01), indicating that for every one point increase in implementation score, ECEC services were 38¿% more likely to be fully implementing the policies and practices. The findings highlight the opportunities for improving implementation of obesity prevention interventions in this setting by developing interventions that address such factors.

DOI 10.1007/s13142-015-0319-y
Citations Scopus - 18Web of Science - 17
Co-authors Rebecca Wyse, Serene Yoong, John Wiggers, Luke Wolfenden, Nicole Nathan, Natasha Weaver
2015 Nathan N, Wolfenden L, Williams CM, Yoong SL, Lecathelinais C, Bell AC, et al., 'Adoption of obesity prevention policies and practices by Australian primary schools: 2006 to 2013', HEALTH EDUCATION RESEARCH, 30 262-271 (2015) [C1]
DOI 10.1093/her/cyu068
Citations Scopus - 6Web of Science - 4
Co-authors Serene Yoong, John Wiggers, Rebecca Wyse, Nicole Nathan, Luke Wolfenden, Christopher M Williams
2015 Yoong SL, Nathan NK, Wyse RJ, Preece SJ, Williams CM, Sutherland RL, et al., 'Assessment of the School Nutrition Environment: A Study in Australian Primary School Canteens', American Journal of Preventive Medicine, 49 215-222 (2015) [C1]

© 2015 American Journal of Preventive Medicine. Introduction Schools represent a valuable setting for interventions to improve children&apos;s diets, as they offer structured oppo... [more]

© 2015 American Journal of Preventive Medicine. Introduction Schools represent a valuable setting for interventions to improve children's diets, as they offer structured opportunities for ongoing intervention. Modifications to the school food environment can increase purchasing of healthier foods and improve children's diets. This study examines the availability of healthy food and drinks, implementation of pricing and promotion strategies in Australian primary school canteens, and whether these varied by school characteristics. Methods In 2012 and 2013, canteen managers of primary schools in the Hunter New England region of New South Wales reported via telephone interview the pricing and promotion strategies implemented in their canteens to encourage healthier food and drink purchases. A standardized audit of canteen menus was performed to assess the availability of healthy options. Data were analyzed in 2014. Results Overall, 203 (79%) canteen managers completed the telephone interview and 170 provided menus. Twenty-nine percent of schools had menus that primarily consisted of healthier food and drinks, and 11% did not sell unhealthy foods. Less than half reported including only healthy foods in meal deals (25%), labeling menus (43%), and having a comprehensive canteen policy (22%). A significantly larger proportion of schools in high socioeconomic areas (OR=3.0) and large schools (OR=4.4) had primarily healthy options on their menus. School size and being a Government school were significantly associated with implementation of some pricing and promotion strategies. Conclusions There is a need to monitor canteen environments to inform policy development and research. Future implementation research to improve the food environments of disadvantaged schools in particular is warranted.

DOI 10.1016/j.amepre.2015.02.002
Citations Scopus - 19Web of Science - 16
Co-authors John Wiggers, Rebecca Wyse, Christopher M Williams, Serene Yoong, Luke Wolfenden, Nicole Nathan
2015 Colin Bell A, Davies L, Finch M, Wolfenden L, Francis JL, Sutherland R, Wiggers J, 'An implementation intervention to encourage healthy eating in centre-based child-care services: Impact of the Good for Kids Good for Life programme', Public Health Nutrition, 18 1610-1619 (2015) [C1]
DOI 10.1017/S1368980013003364
Citations Scopus - 25Web of Science - 26
Co-authors John Wiggers, Luke Wolfenden
2015 Williams CM, Nathan N, Delaney T, Yoong SL, Wiggers J, Preece S, et al., 'CAFÉ: A multicomponent audit and feedback intervention to improve implementation of healthy food policy in primary school canteens: Protocol of a randomised controlled trial', BMJ Open, 5 (2015) [C1]

Introduction: A number of jurisdictions internationally have policies requiring schools to implement healthy canteens. However, many schools have not implemented such policies. On... [more]

Introduction: A number of jurisdictions internationally have policies requiring schools to implement healthy canteens. However, many schools have not implemented such policies. One reason for this isthat current support interventions cannot feasibly be delivered to large numbers of schools. A promising solution to support population-wide implementation of healthy canteen practices is audit and feedback. The effectiveness of this strategy has, however, not previously been assessed in school canteens. This study aims to assess the effectiveness and cost-effectiveness of an audit and feedback intervention, delivered by telephone and email, in increasing the number of school canteens that have menus complying with a government healthy-canteen policy. Methods and analysis: Seventy-two schools, across the Hunter New England Local Health District in New South Wales Australia, will be randomised to receive the multicomponent audit and feedback implementation intervention or usual support. The intervention will consist of between two and four canteen menu audits over 12 months. Each menu audit will be followed by two modes of feedback: a written feedback report and a verbal feedback/support via telephone. Primary outcomes, assessed by dieticians blind to group status and as recommended by the Fresh Tastes @ School policy, are: (1) the proportion of schools with a canteen menu containing foods or beverages restricted for sale, and; (2) the proportion of schools that have a menu which contains more than 50% of foods classified as healthy canteen items. Secondary outcomes are: the proportion of menu items in each category ('red', 'amber' and 'green'), canteen profitability and cost-effectiveness. Ethics and dissemination: Ethical approval has been obtained by from the Hunter New England Human Research Ethics Committee and the University of Newcastle Human Research Ethics Committee. The findings will be disseminated in usual forums, including peer-reviewed publication and conference presentations.

DOI 10.1136/bmjopen-2014-006969
Citations Scopus - 10Web of Science - 9
Co-authors Nicole Nathan, Rebecca Wyse, Luke Wolfenden, Christopher M Williams, John Wiggers, Kathryn L Reilly, Serene Yoong
2014 Wolfenden L, Nathan N, Williams CM, Delaney T, Reilly KL, Freund M, et al., 'A randomised controlled trial of an intervention to increase the implementation of a healthy canteen policy in Australian primary schools: study protocol.', Implement Sci, 9 147 (2014) [C3]
DOI 10.1186/s13012-014-0147-3
Citations Scopus - 18Web of Science - 17
Co-authors Christopher M Williams, Rebecca Wyse, Kathryn L Reilly, Serene Yoong, Megan Freund, Nicole Nathan, Luke Wolfenden, John Wiggers
2013 Sutherland R, Campbell E, Lubans DR, Morgan PJ, Okely AD, Nathan N, et al., 'A cluster randomised trial of a school-based intervention to prevent decline in adolescent physical activity levels: study protocol for the 'Physical Activity 4 Everyone' trial', BMC PUBLIC HEALTH, 13 (2013) [C3]
DOI 10.1186/1471-2458-13-57
Citations Scopus - 24Web of Science - 21
Co-authors John Wiggers, David Lubans, Luke Wolfenden, Nicole Nathan, Philip Morgan
2013 Bell AC, Wolfenden L, Sutherland R, Coggan L, Young K, Fitzgerald M, et al., 'Harnessing the power of advertising to prevent childhood obesity', INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY, 10 (2013) [C1]
DOI 10.1186/1479-5868-10-114
Citations Scopus - 4Web of Science - 3
Co-authors John Wiggers, Rebecca Hodder, Luke Wolfenden
2012 Nathan NK, Wolfenden L, Bell AC, Wyse R, Morgan PJ, Butler MT, et al., 'Effectiveness of a multi-strategy intervention in increasing the implementation of vegetable and fruit breaks by Australian primary schools: A non-randomized controlled trial', BMC Public Health, 12 651 (2012) [C1]
DOI 10.1186/1471-2458-12-651
Citations Scopus - 37Web of Science - 32
Co-authors John Wiggers, Luke Wolfenden, Rebecca Wyse, Philip Morgan, Nicole Nathan
2011 Wolfenden L, Neve M, Farrell L, Lecathelinais C, Bell C, Milat A, et al., 'Physical activity policies and practices of childcare centres in Australia', Journal of Paediatrics and Child Health, 47 73-76 (2011) [C1]
DOI 10.1111/j.1440-1754.2010.01738.x
Citations Scopus - 41Web of Science - 39
Co-authors John Wiggers, Luke Wolfenden, Melinda Hutchesson
2008 Sutherland RL, Finch M, Harrison M, Collins CE, 'Higher prevalence of childhood overweight and obesity in association with gender and socioeconomic status in the Hunter region of New South Wales', Nutrition & Dietetics, 65 192-197 (2008) [C1]
DOI 10.1111/j.1747-0080.2008.00287.x
Citations Scopus - 6Web of Science - 6
Co-authors Clare Collins
2008 Butt AJ, Caldon CE, McNeil CM, Swarbrick A, Musgrove EA, Sutherland RL, 'Cell cycle machinery: Links with genesis and treatment of breast cancer', Advances in Experimental Medicine and Biology, 630 189-205 (2008)

Loss of normal growth control is a hallmark of cancer. Thus, understanding the mechanisms of tissue-specific, normal growth regulation and the changes that occur during tumorigene... [more]

Loss of normal growth control is a hallmark of cancer. Thus, understanding the mechanisms of tissue-specific, normal growth regulation and the changes that occur during tumorigenesis may provide insights of both diagnostic and therapeutic importance. Control of cell proliferation in the normal mammary gland is steroid hormone (estrogen and progestin)-dependent, involves complex interactions with other hormones, growth factors and cytokines and ultimately converges on activation of three proto-oncogenes (c-Myc, cyclin D1 and cyclin E1) that are rate limiting for the G1 to S phase transition during normal cell cycle progression. Mammary epithelial cell-specific overexpression of these genes induces mammary carcinoma in mice, while cyclin D1 null mice have arrested mammary gland development and are resistant to carcinoma induced by the neu/erbB2 and ras oncogenes. Furthermore, c-Myc, cyclins D1, E1 and E2 are commonly overexpressed in primary breast cancer where elevated expression is often associated with a more aggressive disease phenotype and an adverse patient outcome. This may be due in part to overexpression of these genes conferring resistance to endocrine therapies since in vitro studies provide compelling evidence that overexpression of c-Myc and to a lesser extent cyclin D1 and cyclin E1, attenuate the growth inhibitory effects of SERMS, antiestrogens and progestins in breast cancer cells. Thus, abnormal regulation of the expression of cell cycle molecules, involved in the steroidal control of cell proliferation in the mammary gland, are likely to be directly involved in the development, progression and therapeutic responsiveness of breast cancer. Furthermore, a more detailed understanding of these pathways may identify new targets for therapeutic intervention particularly in endocrine-unresponsive and endocrine-resistant disease. © 2008 Landes Bioscience and Springer Science+Business Media.

DOI 10.1007/978-0-387-78818-0_12
Citations Scopus - 51
2008 Lye LH, Kench JG, Handelsman DJ, Scheffer GL, Stricker PD, Grygiel JG, et al., 'Androgen regulation of multidrug resistance-associated protein 4 (MRP4/ABCC4) in prostate cancer', Prostate, 68 1421-1429 (2008)

BACKGROUND. MRP4/ABCC4 is an ATP-binding cassette transporter expressed in normal prostate. This study aimed to define the pattern of MRP4/ABCC4 expression in normal and malignant... [more]

BACKGROUND. MRP4/ABCC4 is an ATP-binding cassette transporter expressed in normal prostate. This study aimed to define the pattern of MRP4/ABCC4 expression in normal and malignant prostate tissue and the relationship of MRP4/ABCC4 expression and function in response to androgen signaling. METHODS. Eighty-four radical prostatectomy specimens from patients with localized prostate cancer (PC) (22 neoadjuvant androgen ablation, AA, 62 no AA), 42 non-cancer and 16 advanced PCs were assessed for MRP4/ABCC4 mRNA/protein expression. The effect of DHT and bicalutamide on LNCaP cells was assessed by immunoblotting. HEK293 cells (+/-MRP4/ABCC4) were assessed for the ability to efflux androgens and anti-androgens. RESULTS. MRP4/ABCC4 mRNA/protein levels were higher in localized PC compared to non-cancer (P = 0.006). MRP4/ABCC4 levels were significantly decreased in PCs treated with AA compared to cancers exposed to normal testosterone levels (P < 0.0001). MRP4/ABCC4 expression in normal human tissues was limited to the prostate and the renal tubules. MRP4/ ABCC4 protein levels increased in LNCaP cells after DHT which was partially blocked by bicalutamide. However, DHT did not alter the activation of the MRP4/ABCC4 promotor in luciferase reporter assays and testosterone, DHT, flutamide and hydroxy-flutamide were not substrates for MRP4/ABCC4. DISCUSSION. Elevated MRP4/ABCC4 expression is found in malignant compared to benign prostate tissue while lower MRP4/ABCC4 expression is seen after AA. Furthermore, MRP4/ ABCC4 is upregulated by androgen and downregulated by anti-androgen treatment in vitro potentially through an indirect mode of action. These data strongly suggest that MRP4/ABCC4 is an androgen-regulated gene important in the progression to PC and may be a potential drug target. © 2008 Wiley-Liss, Inc.

DOI 10.1002/pros.20809
Citations Scopus - 49
2008 Sakko AJ, Butler MS, Byers S, Reinboth BJ, Stahl J, Kench JG, et al., 'Immunohistochemical level of unsulfated chondroitin disaccharides in the cancer stroma is an independent predictor of prostate cancer relapse', Cancer Epidemiology Biomarkers and Prevention, 17 2488-2497 (2008)

The glycosaminoglycan chondroitin sulfate is significantly increased in the peritumoral stroma of prostate tumors compared with normal stroma and is an independent predictor of pr... [more]

The glycosaminoglycan chondroitin sulfate is significantly increased in the peritumoral stroma of prostate tumors compared with normal stroma and is an independent predictor of prostate-specific antigen (PSA) relapse following radical prostatectomy. In this study, we determined whether specific alterations in the sulfation pattern of glycosaminoglycan chains in clinically organ-confined prostate cancer are associated with PSA relapse. Immunoreactivity to distinct glycosaminoglycan disaccharide epitopes was assessed by manually scoring the staining intensity in prostate tissues from patients with benign prostatic hyperplasia (n = 19), early-stage cancer (cohort 1, n = 55 and cohort 2, n = 275), and advanced-stage cancer (n = 20). Alterations to glycosaminoglycans in benign and malignant prostate tissues were determined by cellulose acetate chromatography and high-pressure liquid chromatography. Glycosaminoglycan disaccharide epitopes were localized to the peritumoral stroma of clinically localized prostate cancer. The level of immunostaining for unsulfated disaccharides (C0S) in the peritumoral stroma, but not for 4-sulfated (C4S) or 6-sulfated disaccharides (C6S), was significantly associated with the rate of PSA relapse following radical prostatectomy. High levels of C0S immunostaining were determined to be an independent predictor of PSA relapse (1.6-fold, P = 0.020). Advanced-stage prostate cancer tissues exhibited reduced electrophoretic mobility for chondroitin sulfate and increased unsulfated disaccharides when compared with benign prostatic hyperplasia tissues, whereas the sulfated disaccharide levels were unaffected. The level of C0S immunostaining in the peritumoral stroma is an independent determinant of PSA failure in clinically localized prostate cancer. Specific alterations to chondroitin sulfate side chains occurring during tumor development may be a crucial step for disease progression in prostate cancer. Copyright © 2008 American Association for Cancer Research.

DOI 10.1158/1055-9965.EPI-08-0204
Citations Scopus - 23
2007 Finch M, Begley A, Sutherland RL, Butler MT, Collins CE, 'Development and reproducibility of a tool to assess school food-purchasing practices and lifestyle habits of Australian primary school-aged children', Nutrition and Dietetics, 64 86-92 (2007) [C1]
DOI 10.1111/j.1747-0080.2007.00148.x
Citations Scopus - 7Web of Science - 7
Co-authors Clare Collins
2007 McGowan EM, Russell AJ, Boonyaratanakornkit V, Saunders DN, Lehrbach GM, Sergio CM, et al., 'Progestins reinitiate cell cycle progression in antiestrogen-arrested breast cancer cells through the B-isoform of progesterone receptor', Cancer Research, 67 8942-8951 (2007)

Estrogen treatment of MCF-7 human breast cancer cells allows the reinitiation of synchronous cell cycle progression in antiestrogen-arrested cells. Here, we report that progestins... [more]

Estrogen treatment of MCF-7 human breast cancer cells allows the reinitiation of synchronous cell cycle progression in antiestrogen-arrested cells. Here, we report that progestins also reinitiate cell cycle progression in this model. Using clonal cell lines derived from progesterone receptor (PR)-negative MCF-7M13 cells expressing wild-type or mutant forms of PRA and PRB, we show that this effect is mediated via PRB, not PRA. Cell cycle progression did not occur with a DNA-binding domain mutant of PRB but was unaffected by mutation in the NH2-terminal, SH3 domain interaction motif, which mediates rapid progestin activation of c-Src. Thus, the progestin-induced proliferative response in antiestrogen-inhibited cells is mediated primarily by the transcriptional activity of PRB. Analysis of selected cell cycle targets showed that progestin treatment induced levels of cyclin D1 expression and retinoblastoma protein (Rb) phosphorylation similar to those induced by estradiol. In contrast, progestin treatment resulted in only a 1.2-fold induction of c-Myc compared with a 10-fold induction by estradiol. These results support the conclusion that progestin, in a PRB-dependent manner, can overcome the growth-inhibitory effects of antiestrogens in estrogen receptor/PR-positive breast cancer cells by the induction of cyclin D1 expression. The mediation of this effect by PRB, but not PRA, further suggests a mechanism whereby abnormal regulation of the normal expression ratios of PR isoforms in breast cancer could lead to the attenuation of antiestrogen-mediated growth arrest. ©2007 American Association for Cancer Research.

DOI 10.1158/0008-5472.CAN-07-1255
Citations Scopus - 28
2007 Horvath LG, Lelliott JE, Kench JG, Lee CS, Williams ED, Saunders DN, et al., 'Secreted frizzled-related protein 4 inhibits proliferation and metastatic potential in prostate cancer', Prostate, 67 1081-1090 (2007)

BACKGROUND. Secreted frizzled-related proteins (sFRP4) inhibits Wnt signaling and thus cellular proliferation in androgen-independent prostate cancer cells in vitro. However, incr... [more]

BACKGROUND. Secreted frizzled-related proteins (sFRP4) inhibits Wnt signaling and thus cellular proliferation in androgen-independent prostate cancer cells in vitro. However, increased expression of membranous sFRP4 is associated with a good prognosis in human localized androgen-dependent prostate cancer, suggesting a role for sFRP4 in early stage disease. Here, we investigated the phenotype of sFRP4 overexpression in an androgen-dependent prostate cancer model. METHODS. An sFRP4-overexpressing androgen-dependent (LNCaP) prostate cancer model was established to assess changes in cellular proliferation, the expression, and subcellular localization of adhesion molecules and cellular invasiveness, and compared with the findings in sFRP4-overexpressing androgen-independent cells (PC3). RESULTS. sFRP4 overexpression in both cell line models resulted in a morphologic change to a more epithelioid cell type with increased localization of ß-catenin and cadherins (E-cadherin in LNCaP, N-cadherin in PC3) to the cell membrane. Functionally, sFRP4 overexpression was associated with a decreased rate of proliferation (P = 0.0005), decreased anchorage-independent growth (P < 0.001), and decreased invasiveness in PC3 cells (P < 0.0001). Furthermore, increased membranous sFRP4 expression was associated with increased membranous ß-catenin expression (P = 0.02) in a cohort of 224 localized human androgen-dependent prostate cancers. CONCLUSIONS. These data suggest that sFRP4 is an inhibitor of prostate cancer growth and invasion in vitro independent of androgen receptor (AR) signaling with correlative evidence in human androgen-dependent disease suggesting similar changes in the clinical setting. Consequently, potential therapeutic strategies to modulate Wnt signaling by sFRP4 will be relevant to both localized androgen-dependent prostate cancer and advanced metastatic disease. © 2007 Wiley-Liss, Inc.

DOI 10.1002/pros.20607
Citations Scopus - 38
2007 Kohonen-Corish MRJ, Sigglekow ND, Susanto J, Chapuis PH, Bokey EL, Dent OF, et al., 'Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer', Oncogene, 26 4435-4441 (2007)

The mutated in colorectal cancer (MCC) gene is in close linkage with the adenomatous polyposis coli (APC) gene on chromosome 5, in a region of frequent loss of heterozygosity in c... [more]

The mutated in colorectal cancer (MCC) gene is in close linkage with the adenomatous polyposis coli (APC) gene on chromosome 5, in a region of frequent loss of heterozygosity in colorectal cancer. The role of MCC in carcinogenesis, however, has not been extensively analysed, and functional studies are emerging, which implicate it as a candidate tumor suppressor gene. The aim of this study was to examine loss of MCC expression due to promoter hypermethylation and its clinicopathologic significance in colorectal cancer. Correspondence of MCC methylation with gene silencing was demonstrated using bisulfite sequencing, reverse transcription-polymerase chain reaction and Western blotting. MCC methylation was detected in 45-52% of 187 primary colorectal cancers. There was a striking association with CDKN2A methylation (P<0.0001), the CpG island methylator phenotype (P<0.0001) and the BRAF V600E mutation (P<0.0001). MCC methylation was also more common (P=0.0084) in serrated polyps than in adenomas. In contrast, there was no association with APC methylation or KRAS mutations. This study demonstrates for the first time that MCC methylation is a frequent change during colorectal carcinogenesis. Furthermore, MCC methylation is significantly associated with a distinct spectrum of precursor lesions, which are suggested to give rise to cancers via the serrated neoplasia pathway. © 2007 Nature Publishing Group All rights reserved.

DOI 10.1038/sj.onc.1210210
Citations Scopus - 50
2007 Munoz MA, Saunders DN, Henderson MJ, Clancy JL, Russell AJ, Lehrbach G, et al., 'The E3 ubiquitin ligase EDD regulates S-phase and G

The cellular response to DNA damage is critical for maintenance of genomic integrity and inhibition of tumorigenesis. Mutations or aberrant expression of the E3 ubiquitin ligase E... [more]

The cellular response to DNA damage is critical for maintenance of genomic integrity and inhibition of tumorigenesis. Mutations or aberrant expression of the E3 ubiquitin ligase EDD have been observed in a number of carcinomas and we recently reported that EDD modulates activity of the DNA damage checkpoint kinase, CHK2. Here, we demonstrate that EDD is necessary for G1/S and intra S phase DNA damage checkpoint activation and for the maintenance of G2/M arrest after double strand DNA breaks. Defective checkpoint activation in EDD-depleted cells led to radio-resistant DNA synthesis, premature entry into mitosis, accumulation of polyploid cells, and cell death via mitotic catastrophe. In addition to decreased CHK2 activation in EDD-depleted cells, the expression of several key cell cycle mediators including Cdc25A/C and E2F1 was altered, suggesting that these checkpoint defects may be both CHK2-dependent and -independent. These data support a role for EDD in the maintenance of genomic stability, emphasising the potential importance of dysregulated EDD expression and/or function in the evolution of cancer. ©2007 Landes Bioscience.

DOI 10.4161/cc.6.24.5021
Citations Scopus - 46
2006 Finch M, Sutherland RL, Harrison M, Collins CE, 'Canteen purchasing practices of year 1-6 primary school children and association with SES and weight status', Australian and New Zealand Journal of Public Health, 30 247-251 (2006) [C1]
DOI 10.1111/j.1467-842X.2006.tb00865.x
Citations Scopus - 33Web of Science - 35
Co-authors Clare Collins
1996 Hall RE, Aspinall JO, Horsfall DJ, Birrell SN, Bentel JM, Sutherland RL, Tilley WD, 'Expression of the androgen receptor and an androgen-responsive protein, apolipoprotein D, in human breast cancer', British Journal of Cancer, 74 1175-1180 (1996)

Little is known regarding the activity and function of the androgen receptor (AR) in human breast cancer. In the present study AR was evaluated in untreated primary breast cancers... [more]

Little is known regarding the activity and function of the androgen receptor (AR) in human breast cancer. In the present study AR was evaluated in untreated primary breast cancers using antisera to the amino-and carboxy-termini of the receptor and quantitated using colour video image analysis. A strong correlation between tissue concentration and percentage AR-positive cells was observed for each antiserum. However, comparison of percentage positive cells using the amino- and carboxy-terminal AR antisera in individual breast cancer specimens revealed a subset of tumours with discordantly increased staining for the carboxy terminus. These findings suggest the presence of amino-terminal-truncated AR in a proportion of breast cancer cells or presence of AR mutations or associated protein alterations that affect binding of the amino-terminal AR antiserum. Immunohistochemical expression of the androgen-regulated glycoprotein, apolipoprotein D (apo-D), was also evaluated in the breast cancer specimens. Focal positivity of apo-D staining, which did not always co-localise with AR-positive cells, was observed within breast tumours. Furthermore, no correlation was evident between percentage positive cells stained for AR and apo-D in breast cancer specimens. These findings indicate that, although apo-D expression is androgen regulated in human breast cancer cell lines in vitro, its expression in primary breast cancers may be regulated by other factors. The expression of AR in primary breast cancers also suggests that the receptor may be involved in tumour responsiveness or in abnormal responses to endocrine therapies.

DOI 10.1038/bjc.1996.513
Citations Scopus - 66
1996 Lilischkis R, Sarcevic B, Kennedy C, Warlters A, Sutherland RL, 'Cancer-associated mis-sense and deletion mutations impair p16(INK4) CDK inhibitory activity', International Journal of Cancer, 66 249-254 (1996)

The p16(INK4) gene is a candidate tumour-suppressor gene which maps to the genomic locus 9p21, and mutations of this gene are associated with melanoma and other cancers. Biochemic... [more]

The p16(INK4) gene is a candidate tumour-suppressor gene which maps to the genomic locus 9p21, and mutations of this gene are associated with melanoma and other cancers. Biochemical studies suggest that p16(INK4) mediates its effects by specifically inhibiting the G1 cyclin-dependent kinases CDK4 and CDK6, thereby regulating progression through G1 into S phase of the cell cycle. To evaluate the functional effects of mutations in p16(INK4) which have been observed in primary cancers and cancer cell lines, we constructed a series of deletion mutants comprising amino acid regions 9-72, 9-131, 73-131 and 73-156; a mis-sense mutation identified in melanoma (Arg87Pro); and the polymorphism Ala148Thr and investigated their ability to inhibit cyclin D1/CDK4 kinase activity in vitro. Removal of 25 amino acids from the carboxy terminus of p16(INK4) (9-131) had little impact on its inhibitory activity. In contrast, deletion of the 65 N-terminal amino acids comprising the first and second ankyrin repeats of p16(INK4) (73-131) abolished its inhibitory activity. The carboxy (73-156) and amino terminal (9-72) fragments of p16(INK4) also failed to inhibit cyclin D1/CDK4 activity. These results indicate that the core region (73-131) as well as amino acids N-terminal of this sequence are important, whereas sequences C-terminal of amino acid 131 are less important for the inhibitory activity of this molecule. The melanoma-associated Arg87Pro mutation resulted in loss of inhibitory activity, whereas the Ala148Thr polymorphic variant was as effective as the alanine variant of p16(INK4) in inhibiting D1/CDK4 kinase activity. Binding assays revealed that inhibition was invariably associated with p16(INK4) binding to CDK4. Hence, our studies indicate that minor perturbations in p16(INK4) primary structure can lead to loss of its inhibitory activity, possibly contributing to oncogenesis in numerous cell types.

DOI 10.1002/(SICI)1097-0215(19960410)66:2&lt;249::AID-IJC19&gt;3.0.CO;2-7
Citations Scopus - 67
1996 Sweeney KJ, Musgrove EA, Watts CK, Sutherland RL, 'Cyclins and breast cancer.', Cancer treatment and research, 83 141-170 (1996)
DOI 10.1007/978-1-4613-1259-8_8
Citations Scopus - 15
1996 Musgrove EA, Hui R, Sweeney KJ, Watts CK, Sutherland RL, 'Cyclins and breast cancer.', Journal of mammary gland biology and neoplasia, 1 153-162 (1996)

Recent advances in the understanding of cell cycle control by cyclins and cyclin-dependent kinases provide a basis for delineating the molecular mechanisms of proliferation contro... [more]

Recent advances in the understanding of cell cycle control by cyclins and cyclin-dependent kinases provide a basis for delineating the molecular mechanisms of proliferation control by steroids and the development and progression of hormone-dependent cancers. Cyclin D1 is necessary, rate-limiting and sufficient for G1 progression in breast cancer cells and regulation of cyclin D1 expression or function is an early response to steroid and steroid antagonist regulation of proliferation. The cyclin D1 gene is amplified in approximately 15%, and its product overexpressed in 40-50%, of primary breast carcinomas. The strong evidence that cyclin D1 plays a major role in cell cycle control in breast epithelial cells suggests that its deregulated expression may have effects on disease progression and phenotype including sensitivity to endocrine therapies.

DOI 10.1007/BF02013639
Citations Scopus - 34
1992 Watts CKW, Handel ML, King RJB, Sutherland RL, 'Oestrogen receptor gene structure and function in breast cancer', Journal of Steroid Biochemistry and Molecular Biology, 41 529-536 (1992)

The mechanisms underlying loss of oestrogen responsiveness in breast cancer are not well-defined. Potential mechanisms include loss of receptor expression, alterations in the oest... [more]

The mechanisms underlying loss of oestrogen responsiveness in breast cancer are not well-defined. Potential mechanisms include loss of receptor expression, alterations in the oestrogen receptor (ER) gene producing proteins with abnormal function, or changes to receptor-dependent or -independent pathways controlling cell proliferation. Examination by Southern analysis of the ER gene in a series of ER-negative and -positive breast tumour biopsies failed to provide evidence of gross rearrangements and in only only one of thirty seven tumour DNA samples was significant gene amplification observed. No restriction fragment length polymorphisms were detected for the restriction enzymes EcoRI, Pst I or Hind III. Methylation of the ER gene as assessed by Hpa II and Msp I restriction enzyme digests varied between tumours but the degree of methylation was not correlated with levels of expression of the receptor protein. Similar findings applied in a series of ER-negative and -positive breast cancer cell lines and clonal lines of MCF-7 cells, which were developed as an in vitro model for the acquisition of oestrogen and antioestrogen resistance. In this model there was no evidence that changes to ER receptor function and/or structure at the level of the ER gene, mRNA, ligand binding, and ability to induce progesterone receptor might account for the development of hormone resistance. However, the ability of ER to interact with a DNA sequence containing the vitellogenin promoter oestrogen response element, as assessed by gel retardation assay, was impaired in the clone showing the greatest degree of oestrogen and antioestrogen resistance. © 1992.

DOI 10.1016/0960-0760(92)90378-V
Citations Scopus - 46
1992 Musgrove E, Sutherland R, 'Hormones and breast cancer', Today's Life Science, 4 34-37 (1992)
1990 Lee CSL, Hall RE, Alexander IE, Koga M, Shine J, Sutherland RL, 'Inverse relationship between estrogen receptor and epidermal growth factor receptor mRNA levels in human breast cancer cell lines', Growth Factors, 3 97-103 (1990)

Epidermal growth factor receptors (EGF-R) are present in a number of human breast cancer cell lines and tumor biopsies. Furthermore, it has been suggested that EGF-R levels are hi... [more]

Epidermal growth factor receptors (EGF-R) are present in a number of human breast cancer cell lines and tumor biopsies. Furthermore, it has been suggested that EGF-R levels are higher in estrogen receptor negative (ER-) than in ER + human breast tumors and that EGF-R status may be a prognostic indicator in breast cancer. The present study was undertaken to establish whether there is a quantitative relationship between EGF-R and ER mRNA concentrations in a series of 10 well-characterized human breast cancer cell lines. All cell lines expressed detectable quantities of EGF-R mRNA by Northern analysis but the relative abundance of EGF-R mRNA varied more than 50-fold. Two transcripts corresponding to the 10.5- and 5.8-kb mRNAs described in other cell types were present but in different relative proportions in different cell lines. When these lines were divided into an ER+ and an ER- group based on their ability to bind estradiol, ER- cell lines were shown to express significantly higher concentrations of EGF-R mRNA than did ER+ cell lines (p < 0.005). Furthermore, linear-regression analysis revealed a significant inverse relationship between ER and EGF-R mRNA concentrations both within the group of 10 human breast cancer cell lines as a whole (r = 0.66) and within the 6 functionally ER+ lines (r = 0.77). This demonstration of a significant (p < 0.005) inverse relationship between the concentrations of ER and EGF-R mRNAs in ER + cell lines raises the possibility of reciprocal regulation of the expression of these genes in human breast cancer. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

DOI 10.3109/08977199009108272
Citations Scopus - 22
1989 Lee CSL, Koga M, Sutherland RL, 'Modulation of estrogen receptor and epidermal growth factor receptor mRNAs by phorbol ester in MCF 7 breast cancer cells', Biochemical and Biophysical Research Communications, 162 415-421 (1989)

Previous studies have demonstrated an inverse relationship between estrogen receptor (ER) and epidermal growth factor receptor (EGF-R) gene expression in human breast cancer cells... [more]

Previous studies have demonstrated an inverse relationship between estrogen receptor (ER) and epidermal growth factor receptor (EGF-R) gene expression in human breast cancer cells. This relationship was further investigated in MCF 7 cells treated with 12-O-tetradecanoylphorbol-13-acetate (TPA). Exposure to 10 nM TPA resulted in a time-dependent increase in EGF-R mRNA, first apparent at 3 h and maximal between 9 and 24 h. There was a concomitant fall in ER mRNA with a maximum decline to 15-20% of control between 12 and 24 h. Although EGF-R mRNA levels declined between 24 and 72 h, both EGF-R mRNA and EGF-R binding remained above control levels and this was accompanied by a sustained depression of ER mRNA. These data support the view that ER and EGF-R gene expression is inversely regulated in human breast cancer and describe for the first time an inhibitory effect of a phorbol ester on steroid hormone receptor gene expression. © 1989.

DOI 10.1016/0006-291X(89)92013-5
Citations Scopus - 36
1989 Ewing TM, Murphy LJ, Ng M, Pang GYN, Lee CSL, Watts CKW, Sutherland RL, 'Regulation of epidermal growth factor receptor by progestins and glucocorticoids in human breast cancer cell lines', International Journal of Cancer, 44 744-752 (1989)

Human breast cancer cells secrete a number of autocrine peptides which modulate their proliferation rates. The known effects of steroid hormones on breast cancer cell proliferatio... [more]

Human breast cancer cells secrete a number of autocrine peptides which modulate their proliferation rates. The known effects of steroid hormones on breast cancer cell proliferation may be mediated in part by altering the production of these growth factors and/or their interactions with cellular receptor sites. Receptors for epidermal growth factor (EGF), which also bind the autocrine growth factor, a-transforming growth factor, are present on a number of breast cancer cell lines and it has previously been shown that T-47D and MCF-7 cells respond to progestins with an increase in the concentration of EGF receptors (EGF-R). In the present study we examined the effects of both progestins and glucocorticoids on EGF binding in 10 human breast cell lines. Five of these lines were progesterone receptor positive and all lines expressed the glucocorticoid receptor (GR). All cell lines were initially incubated for 24 hr with increasing concentrations of the synthetic progestin, medroxyprogesterone acetate (MPA), and the level of specifically bound EGF was determined. An increase in specific binding of EGF was confirmed in two PR-positive lines but, in addition, increases in EGF binding were observed in 4 PR-negative cell lines. In these last lines the synthetic glucocorticoid, dexamethasone, was a more potent inducer of EGF binding than MPA, a known glucocorticoid agonist, while the high-affinity PR ligand, ORG 2058, was without effect. Furthermore, MPA competed with dexamethasone for binding to GR in these cell lines, supporting the view that the induction of EGF binding by MPA in these cells was mediated via the GR. This conclusion was further supported by studies in which addition of the glucocorticoid and progestin antagonist, RU 486, inhibited the effect of ORG 2058 in two cell lines and completely abrogated the effect of dexamethasone in two other lines. Detailed binding studies revealed that the increase in EGF binding was accompanied by an increase in the concentration of EGF-R. This effect was observed when EGF binding was assayed at either 0° or 37°C. Further studies demonstrated that the increases in EGF binding following ORG 2058 and dexamethasone treatment were accompanied by increases in EGF-R mRNA levels. Our data illustrate that the binding of EGF by some human breast cancer cells can be regulated by both progestins and glucocorticoids acting vía their respective receptors and inducing increases in EGF-R mRNA levels. Copyright © 1989 Wiley-Liss, Inc., A Wiley Company

DOI 10.1002/ijc.2910440432
Citations Scopus - 50
1989 Eisman JA, Koga M, Sutherland RL, Barkla DH, Tutton PJM, '1,25-Dihydroxyvitamin D

Several human and animal cancer cell lines have been shown to possess specific high affinity receptors for 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3). The replication of several of t... [more]

Several human and animal cancer cell lines have been shown to possess specific high affinity receptors for 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3). The replication of several of these cell types has also been shown to be regulated by this hormone, both in vitro and in vitro. To further understand the mechanisms of these actions, we have examined cancer cells in vitro and in vitro. The in vitro studies extend our previous reports on the treatment of human breast cancer cells (T 47D) with 10-9 to 10-8 M 1,25-(OH)2D3, which resulted in a dose- and time-dependent decrease in cell numbers over 6 days. Treatment with 10-8 M 1,25-(OH)2D3, which reduced cell numbers to approximately one half of those found in control cultures at 6 days, was associated with a doubling of the proportion of cells in the G2 + M phase of the cell cycle and was accompanied by a significant decline in the proportion of G0/G1 cells. At higher concentrations there was a significant decline in 5 phase cells with accumulation of cells in both G0/G1 and G2 + M phases. The antiestrogen, tamoxifen, at a concentration which caused similar effects on cell number, resulted in proportional decreases in both S and Gz + M phase cells and accumulation of G0G1 cells. The effects of 1,25-(OH)2D3 on T 47D cell proliferation were associated with time- and concentration-dependent reductions in epidermal growth factor receptor levels to a minimum level of about half that seen in control cultures. The in vivo experiments extend our previous studies, which demonstrated marked inhibition of the growth of human cancer xenografts in immunosuppressed mice by 1,25-(OH)2D3. Xenograft growth was inhibited with 1,25-(OH)2D3 (0.1 µg ip three times per week) but growth was rapidly restored when the 1,25-(OH)2D3 was withdrawn. Thus, there are clear-cut time- and dose-dependent, yet reversible, effects of 1,25-(OH)2D3 on the replication of human cancer cells in vitro and in vivo, which are possibly mediated through changes in growth factor receptor levels. Further study of these effects may advance understanding of the hormonal control of cellular replication in human cancers. © 1989, SAGE Publications. All rights reserved.

DOI 10.3181/00379727-191-42912
Citations Scopus - 67
Show 90 more journal articles

Review (1 outputs)

Year Citation Altmetrics Link
2011 Pajic M, Scarlett CJ, Chang DK, Sutherland RL, Biankin AV, 'Preclinical strategies to define predictive biomarkers for therapeutically relevant cancer subtypes', Human Genetics (2011) [D1]
DOI 10.1007/s00439-011-0990-0
Citations Scopus - 13Web of Science - 12
Co-authors C Scarlett

Conference (28 outputs)

Year Citation Altmetrics Link
2020 Ooi JY, Yoong SL, Sutherland R, Wrigley J, Lecathelinais C, Reilly K, et al., 'Prevalence of current school-level nutrition policies and practices of secondary schools in NSW, Australia', HEALTH PROMOTION JOURNAL OF AUSTRALIA (2020)
DOI 10.1002/hpja.357
Co-authors Luke Wolfenden, Serene Yoong, Kathryn L Reilly, Nicole Nathan
2019 Sutherland R, Reynolds R, Janssen L, Muddle R, Chooi A, Brown A, et al., 'Assessing the Potential Effectiveness of Dissemination Strategies on Uptake of an Evidence-Based Program to Improve Packing of Healthy Student Lunchboxes', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2019)
Co-authors Luke Wolfenden
2019 McLaughlin M, Brown A, Elton B, Young S, Wrigley J, Barnes C, et al., 'Bridging the Gap Between Research and Practice: A System for Knowledge Translation', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2019)
Co-authors Matthew Mclaughlin Mc
2018 Sutherland R, Nathan N, Lubans D, Butler P, McCarthy N, Desmet C, et al., 'Effectiveness of a randomized controlled trial to scale up an efficacious school-based intervention to improving children's MVPA', Effectiveness of a randomized controlled trial to scale up an efficacious school-based intervention to improving children's MVPA., London (2018)
DOI 10.1123/jpah.2018-0535
Co-authors Luke Wolfenden, Matthew Mclaughlin Mc, David Lubans, Nicole Nathan
2018 Mclaughlin M, McKenzie T, Sutherland R, Campbell E, Nathan N, Gillham K, et al., 'Results of a systematic and theoretical approach to scaling-up an efficacious school-based physical activity intervention for adolescents: Physical Activity for Everyone ', Results of a systematic and theoretical approach to scaling-up an efficacious school-based physical activity intervention for adolescents: Physical Activity for Everyone , London (2018)
DOI 10.13140/RG.2.2.30218.72643
Co-authors Luke Wolfenden, John Wiggers, Philip Morgan, Nicole Nathan, Matthew Mclaughlin Mc, David Lubans
2018 Nathan N, Yoong SL, Reilly K, Sutherland R, Wiggers J, Wolfenden L, 'Increasing Australian schools' implementation of a mandatory state-wide school healthy food policy: results of three randomised-controlled trials', IMPLEMENTATION SCIENCE (2018)
Co-authors John Wiggers, Luke Wolfenden, Nicole Nathan, Serene Yoong, Kathryn L Reilly
2018 Nathan N, Sutherland R, Beauchamp M, Hulteen R, Wolfenden L, Lubans D, Cohen K, 'Implementation of an elementary school peer-teching physical activity program: learnings from a non-randomised trial', JOURNAL OF PHYSICAL ACTIVITY & HEALTH (2018)
Co-authors David Lubans, Nicole Nathan, Luke Wolfenden
2018 Nathan N, Elton B, Babic M, McCarthy N, Sutherland R, Presseau J, et al., 'A systematic review of barriers and facilitators to the implementation of physical activity policies in schools', JOURNAL OF PHYSICAL ACTIVITY & HEALTH (2018)
Co-authors Luke Wolfenden, Nicole Nathan, Serene Yoong
2018 Delaney T, Wolfenden L, Yoong S, Sutherland R, Wiggers J, Rissel C, Wyse R, 'A Cluster Randomized Controlled Trial of a Consumer Behavior Intervention to Improve Healthy Food Purchases From Online Canteens', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2018)
Citations Web of Science - 1
Co-authors Rebecca Wyse, Serene Yoong, Luke Wolfenden, John Wiggers
2018 Brown A, Sutherland R, Nathan N, Lecathelinais C, Reynolds R, Janssen L, et al., 'Assessing the Effectiveness, Feasibility and Acceptability of an m-Health Intervention to Improve the NutritionalQuality of Primary School Aged Children's Lunchboxes', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2018)
Co-authors John Wiggers, Nicole Nathan, Serene Yoong, Luke Wolfenden
2018 Pond N, Finch M, Yoong S, Jones J, Sutherland R, Wolfenden L, Kingsland M, 'Using the Behavior Change Wheel to Inform an App-Based Intervention to Increase Parents' Packing of Healthy Lunchbox Foods for Children Attending Center-Based Childcare', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2018)
Co-authors Luke Wolfenden, Serene Yoong
2016 Sutherland R, Hollis J, Campbell E, Lubans DR, Morgan PJ, Nathan N, et al., 'EFFECTS OF A SCHOOL-BASED PHYSICAL ACTIVITY INTERVENTION ON ADIPOSITY IN ADOLESCENTS FROM ECONOMICALLY DISADVANTAGED COMMUNITIES: 'PHYSICAL ACTIVITY 4 EVERYONE' RCT.', INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE (2016)
Co-authors Nicole Nathan, Philip Morgan, Luke Wolfenden, David Lubans, Christopher Oldmeadow, John Wiggers
2016 Finch M, Nathan N, Yoong S, Sutherland R, Seward K, Reilly K, et al., 'SUPPORTING THE IMPLEMENTATION OF STATE NUTRITION GUIDELINES AND POLICIES IN SCHOOLS AND CHILDCARE: APPLICATION OF THE THEORETICAL DOMAINS FRAMEWORK', INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE (2016)
Co-authors Luke Wolfenden, Nicole Nathan, John Wiggers, Serene Yoong, Kathryn L Reilly
2016 Yoong S, Nathan N, Finch M, Sutherland R, Seward K, Reilly K, et al., 'IMPLEMENTING STATE NUTRITION GUIDELINES AND POLICIES IN SCHOOLS AND CENTRE BASED CHILDCARE: BARRIERS AND ENABLERS', INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE (2016)
Co-authors Luke Wolfenden, Serene Yoong, Nicole Nathan, John Wiggers, Kathryn L Reilly
2016 Nathan N, Yoong S, Reilly K, Delaney T, Janssen L, Sutherland R, et al., 'THEORY-INFORMED INTERVENTIONS TO INCREASE IMPLEMENTATION OF A MANDATORY HEALTHY FOOD POLICY IN SCHOOLS. APPLICATION OF THE THEORETICAL DOMAINS FRAMEWORK.', INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE (2016)
Co-authors Serene Yoong, Kathryn L Reilly, Nicole Nathan, John Wiggers, Luke Wolfenden
2016 Wyse R, Yoong SL, Dodds P, Campbell L, Delaney T, Nathan N, et al., 'THE POTENTIAL OF ONLINE CANTEENS TO DELIVER PUBLIC HEALTH NUTRITION INTERVENTIONS TO SCHOOL COMMUNITIES', INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE (2016)
Co-authors Rebecca Wyse, Nicole Nathan, Luke Wolfenden, John Wiggers, Serene Yoong, Kathryn L Reilly
2016 Nathan N, Sutherland R, Gillham K, Wiggers J, Wolfenden L, 'CREATING HEALTHY ACTIVE LEADERS FOR KIDS (CHALK): PRINCIPALS AND TEACHERS ACCEPTABILITY OF A TEACHER'S HEALTH INITIATIVE', INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE (2016)
Co-authors Luke Wolfenden, John Wiggers, Nicole Nathan
2016 Nathan N, Yoong S, Williams C, Reilly K, Delaney T, Sutherland R, et al., 'INCREASING THE IMPLEMENTATION OF A STATE-WIDE HEALTHY CANTEEN POLICY: RESULTS OF THREE RANDOMISED-CONTROLLED TRIALS', INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE (2016)
Co-authors Luke Wolfenden, Serene Yoong, John Wiggers, Nicole Nathan, Kathryn L Reilly
2016 Sutherland RR, Campbell E, Lubans DR, Morgan PJ, Nathan N, Wolfenden L, et al., 'PHYSICAL ACTIVITY 4 EVERYONE' CLUSTER RCT: 24-MONTH PHYSICAL ACTIVITY OUTCOMES OF A SCHOOL-BASED PHYSICAL ACTIVITY INTERVENTION TARGETING ADOLESCENTS', INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE (2016)
Co-authors Nicole Nathan, Luke Wolfenden, Philip Morgan, Christopher Oldmeadow, John Wiggers, David Lubans
2016 Sutherland R, Reeves P, Campbell E, Lubans DR, Morgan PJ, Nathan N, et al., 'IS A SCHOOL-BASED PHYSICAL ACTIVITY INTERVENTION TARGETING SECONDARY SCHOOL STUDENTS COST EFFECTIVE?', INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE (2016)
Co-authors Nicole Nathan, John Wiggers, David Lubans, Luke Wolfenden, Philip Morgan
2015 Sutherland RL, Campbell L, Lubans D, Morgan P, Oakley A, Nathan N, et al., 'Mid-intervention findings from the Physical Activity 4 Every1 trial: a cluster RCT in secondary schools located in low-income communities', Edinburgh, UK (2015) [E3]
Co-authors Nicole Nathan, John Wiggers, Philip Morgan, Luke Wolfenden, David Lubans
2014 Nathan N, Wolfenden L, Williams CM, Yoong SL, Lecathelinais C, Bell AC, et al., 'Physical Activity Policies and Practices in Australian Primary Schools 2006-2013: How Far Have We Really Come?', JOURNAL OF PHYSICAL ACTIVITY & HEALTH, Toronto, CANADA (2014)
Co-authors Serene Yoong, John Wiggers, Luke Wolfenden, Rebecca Wyse, Nicole Nathan
2014 Wolfenden L, Finch M, Yoong SL, Nathan N, Waever N, Jones J, et al., 'FACTORS ASSOCIATED WITH THE IMPLEMENTATION OF OBESITY PREVENTION PRACTICES IN AUSTRALIAN CHILDCARE SERVICES', INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE, Brainerd, MN (2014)
Co-authors Rebecca Wyse, Luke Wolfenden, Serene Yoong, Nicole Nathan, John Wiggers
2014 Wiggers JH, Nathan N, Wolfenden L, Williams CM, Yoong SZ, Lecathelinais C, et al., 'OBESITY PREVENTION POLICIES AND PRACTICES IN AUST RALIAN PRIMARY SCHOOLS 2006-2013: HOW FAR HAVE WE COME?', INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE (2014)
Co-authors Serene Yoong, John Wiggers, Christopher M Williams, Luke Wolfenden, Nicole Nathan, Rebecca Wyse
2014 Sutherland R, Campbell E, Lubans DR, Morgan PJ, Okely AD, Nathan N, et al., 'Objectively Measured Sedentary Behavior in Secondary School Physical Education Lessons', JOURNAL OF PHYSICAL ACTIVITY & HEALTH, Toronto, CANADA (2014)
Co-authors John Wiggers, David Lubans, Luke Wolfenden, Nicole Nathan, Philip Morgan
2009 Wolfenden L, Hutchesson MJ, Farrell L, Lecathelinais LC, Sutherland RL, Bell C, et al., 'Physical activity policies and practices in childcare centres: A population based study', Journal of Science and Medicine in Sport, Brisbane, QLD (2009) [E3]
Co-authors John Wiggers, Melinda Hutchesson, Luke Wolfenden
2007 Finch M, Sutherland RL, Collins CE, 'School food purchasing patterns of Hunter primary school children', Program and Abstracts of the 23rd National Dietitians Association of Australia Conference, Perth (2007) [E3]
Co-authors Clare Collins
2005 Sutherland RL, Finch M, Harrison M, Collins CE, 'Obesity prevalence is greater amongst children from a low SES background and greater in females', Proceedings of the 36th PHAA Conference, Perth (2005) [E3]
Co-authors Clare Collins
Show 25 more conferences

Report (1 outputs)

Year Citation Altmetrics Link
2011 Allman-Farinelli M, Collins CE, Williams P, Gifford J, Byron A, Truby H, et al., 'A review of the evidence to address targeted questions to inform the revision of the Australian Dietary Guidelines (Evidence Report).', National Health and Medical Research Council, 1078 (2011) [R1]
Co-authors Melinda Hutchesson, Clare Collins, Lesley Wicks, Alexis Hure, Surinder Baines, Amanda Patterson, Alison A Fielding, Tracy Burrows
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Grants and Funding

Summary

Number of grants 14
Total funding $4,363,606

Click on a grant title below to expand the full details for that specific grant.


20211 grants / $1,562,250

A big problem needs a big solution: Advancing the science of scaling up chronic disease prevention interventions$1,562,250

Funding body: Department of Health

Funding body Department of Health
Project Team Doctor Rachel Sutherland, Doctor Rachel Sutherland
Scheme MRFF Investigator
Role Lead
Funding Start 2021
Funding Finish 2025
GNo G2000052
Type Of Funding C1300 - Aust Competitive - Medical Research Future Fund
Category 1300
UON Y

20203 grants / $1,245,459

A randomised trial of an intervention to sustain schools’ implementation of a state-wide physical activity policy$1,054,151

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Nicole Nathan, Associate Professor Luke Wolfenden, Professor John Wiggers, Doctor Rachel Sutherland, Adrian Bauman, Chris Rissel, Patti-Jean Naylor
Scheme Partnership Projects
Role Investigator
Funding Start 2020
Funding Finish 2026
GNo G1900842
Type Of Funding C1100 - Aust Competitive - NHMRC
Category 1100
UON Y

Harnessing digital innovation in High School Canteens to reduce cardiovascular dietary risk factors$150,000

Funding body: National Heart Foundation of Australia

Funding body National Heart Foundation of Australia
Project Team Doctor Rebecca Wyse, Doctor Serene Yoong, Associate Professor Luke Wolfenden, Doctor Rachel Sutherland
Scheme Vanguard Grant
Role Investigator
Funding Start 2020
Funding Finish 2021
GNo G1900819
Type Of Funding C1700 - Aust Competitive - Other
Category 1700
UON Y

SWAP-IT Healthy lunchbox program$41,308

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Rachel Sutherland, Doctor Nicole Nathan, Doctor Rachel Sutherland, Associate Professor Luke Wolfenden
Scheme Research Grant
Role Lead
Funding Start 2020
Funding Finish 2021
GNo G2001068
Type Of Funding C3120 - Aust Philanthropy
Category 3120
UON Y

20191 grants / $22,000

Disseminating an efficacious healthy eating intervention to primary schools across the Hunter New England region$22,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Rebecca Wyse, Doctor Rebecca Hodder, Doctor Rachel Sutherland, Doctor Nicole Nathan
Scheme Research Grant
Role Investigator
Funding Start 2019
Funding Finish 2020
GNo G1901537
Type Of Funding C3120 - Aust Philanthropy
Category 3120
UON Y

20185 grants / $886,606

A technology based solution to support parents to improve their child’s diet ‘Swap What’s Packed in the lunchbox: ‘SWAP-It’$499,500

Funding body: nib Foundation

Funding body nib Foundation
Project Team Associate Professor Luke Wolfenden, Doctor Rachel Sutherland, Doctor Nicole Nathan, Doctor Serene Yoong, Professor John Wiggers
Scheme Multi-Year Partnerships
Role Investigator
Funding Start 2018
Funding Finish 2021
GNo G1700907
Type Of Funding C3112 - Aust Not for profit
Category 3112
UON Y

A randomised trial of an intervention to facilitate the implementation of evidence based secondary school physical activity practices$182,810

Funding body: NHMRC (National Health & Medical Research Council)

Funding body NHMRC (National Health & Medical Research Council)
Project Team Doctor Rachel Sutherland
Scheme Translating Research into Practice (TRIP) Fellowships
Role Lead
Funding Start 2018
Funding Finish 2020
GNo G1700892
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Addressing the health risk behaviours of the education workforce: A program to enhance the wellbeing of primary school teachers$124,700

Funding body: Teachers Health Foundation

Funding body Teachers Health Foundation
Project Team Doctor Nicole Nathan, Associate Professor Luke Wolfenden, Doctor Serene Yoong, Associate Professor Flora Tzelepis, Doctor Rachel Sutherland, Doctor Rebecca Hodder, Doctor Kathryn Reilly, Doctor Elaine Toomey
Scheme Research Funding
Role Investigator
Funding Start 2018
Funding Finish 2020
GNo G1800853
Type Of Funding C3112 - Aust Not for profit
Category 3112
UON Y

Enhancing Teacher's Health$70,000

Funding body: Hunter New England Population Health

Funding body Hunter New England Population Health
Project Team Doctor Nicole Nathan, Associate Professor Luke Wolfenden, Doctor Serene Yoong, Associate Professor Flora Tzelepis, Doctor Rachel Sutherland, Doctor Rebecca Hodder, Doctor Kathryn Reilly, Doctor Elaine Toomey
Scheme Research Project
Role Investigator
Funding Start 2018
Funding Finish 2018
GNo G1800924
Type Of Funding C2220 - Aust StateTerritoryLocal - Other
Category 2220
UON Y

SDVCRI Research Support for NHMRC TRIP Fellowship$9,596

Funding body: University of Newcastle

Funding body University of Newcastle
Project Team Doctor Rachel Sutherland
Scheme Special Project Grant
Role Lead
Funding Start 2018
Funding Finish 2019
GNo G1800745
Type Of Funding Internal
Category INTE
UON Y

20171 grants / $25,000

A randomised controlled trial to assess the impact of a uniform intervention on girl’s physical activity at school$25,000

Funding body: Hunter Medical Research Institute

Funding body Hunter Medical Research Institute
Project Team Doctor Nicole Nathan, Associate Professor Luke Wolfenden, Doctor Rachel Sutherland, Doctor Serene Yoong, Professor John Wiggers
Scheme Project Grant
Role Investigator
Funding Start 2017
Funding Finish 2017
GNo G1701511
Type Of Funding C3120 - Aust Philanthropy
Category 3120
UON Y

20161 grants / $78,030

Research to gather baseline data regarding operations and provision of healthy food and drinks of licensed school canteens$78,030

Funding body: Health Administration Corporation

Funding body Health Administration Corporation
Project Team Associate Professor Luke Wolfenden, Professor John Wiggers, Doctor Rebecca Wyse, Ms Tessa Delaney, Doctor Serene Yoong, Doctor Rachel Sutherland, Ms Nicole Nathan
Scheme Research Grant
Role Investigator
Funding Start 2016
Funding Finish 2016
GNo G1600903
Type Of Funding C2210 - Aust StateTerritoryLocal - Own Purpose
Category 2210
UON Y

20132 grants / $544,261

Moving from policy to practice: A randomised trial of an implementation intervention to facilitate the adoption of a statewide healthy canteen policy$416,263

Funding body: ARC (Australian Research Council)

Funding body ARC (Australian Research Council)
Project Team Associate Professor Luke Wolfenden, Professor John Wiggers, Conjoint Associate Professor Andrew Bell, Doctor Megan Freund, Ms Karen Gillham, Doctor Libby Campbell, Doctor Rachel Sutherland, Dr Nicole Nathan, Campbell, Elizabeth, Gillham, Karen, Sutherland, Rachel
Scheme Linkage Projects
Role Investigator
Funding Start 2013
Funding Finish 2015
GNo G1201168
Type Of Funding Aust Competitive - Commonwealth
Category 1CS
UON Y

Moving from policy to practice: A randomised trial of an implementation intervention to facilitate the adoption of a statewide healthy canteen policy$127,998

Funding body: Hunter New England Population Health

Funding body Hunter New England Population Health
Project Team Associate Professor Luke Wolfenden, Professor John Wiggers, Conjoint Associate Professor Andrew Bell, Doctor Megan Freund, Ms Karen Gillham, Doctor Libby Campbell, Doctor Rachel Sutherland, Dr Nicole Nathan, Campbell, Elizabeth, Campbell, Elizabeth, Gillham, Karen, Gillham, Karen, Sutherland, Rachel, Sutherland, Rachel
Scheme Linkage Projects Partner Funding
Role Investigator
Funding Start 2013
Funding Finish 2015
GNo G1300710
Type Of Funding Other Public Sector - State
Category 2OPS
UON Y
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Research Supervision

Number of supervisions

Completed0
Current7

Current Supervision

Commenced Level of Study Research Title Program Supervisor Type
2019 PhD The Impact of School Uniforms on Students Physical Activity at School PhD (Public Health & BehavSci), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2018 PhD An m-health nutrition intervention targeting parent packing of lunchboxes to improve the dietary intake of children attending childcare services PhD (Public Health & BehavSci), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2018 PhD Childhood Obesity Prevention PhD (Behavioural Science), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2018 PhD A Cluster Randomised Controlled Trial of an Intervention to Increase the Implementation of School Physical Activity Policies and Guidelines PhD (Public Health & BehavSci), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2018 PhD Addressing Sedentary Behaviour and Physical Inactivity to Reduce Chronic Disease Risk PhD (Public Health & BehavSci), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2017 PhD Acceptability, Feasibility and Potential Effectiveness of a Secondary School Nutrition Intervention PhD (Behavioural Science), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
2015 PhD The efficacy of an online public health nutrition intervention on improving healthy food purchases from primary school canteens PhD (Behavioural Science), Faculty of Health and Medicine, The University of Newcastle Co-Supervisor
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News

More than $10 million to support innovations in health service delivery

May 21, 2020

Six projects led by Hunter researchers have been successful in attracting a combined total of $10.6 million in the latest round of competitive National Health and Medical Research Council (NHMRC) funding.

Funding success to improve health outcomes

April 12, 2018

Researchers from the University of Newcastle (UON), Hunter Medical Research Institute (HMRI) and Hunter New England Health have been awarded more than $600,000 in National Health and Medical Research Council (NHMRC) funding.

Dr Rachel Sutherland

Position

Conjoint Lecturer
School of Health Sciences
Faculty of Health and Medicine

Focus area

Nutrition and Dietetics

Contact Details

Email rachel.sutherland@newcastle.edu.au
Phone ####

Office

Location Callaghan
University Drive
Callaghan, NSW 2308
Australia
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