2023 |
Davidson SR, Robson E, O'Brien KM, Kamper SJ, Haskins R, Ajitsaria P, et al., 'Individuals with musculoskeletal conditions awaiting orthopaedic surgery consultation: an untapped opportunity for patient health management?', Public Health Res Pract, (2023) [C1]
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2022 |
Robson E, Kamper SJ, Lee H, Palazzi K, O'Brien KM, Williams A, et al., 'Compliance with telephone-based lifestyle weight loss programs improves low back pain but not knee pain outcomes: complier average causal effects analyses of 2 randomised trials.', Pain, 163 e862-e868 (2022) [C1]
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Nova |
2022 |
Wolfenden L, McCrabb S, Barnes C, O'Brien KM, Ng KW, Nathan NK, et al., 'Strategies for enhancing the implementation of school-based policies or practices targeting diet, physical activity, obesity, tobacco or alcohol use.', The Cochrane database of systematic reviews, 8 CD011677 (2022) [C1]
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Nova |
2022 |
Hodder RK, O'Brien KM, Lorien S, Wolfenden L, Moore THM, Hall A, et al., 'Interventions to prevent obesity in school-aged children 6-18 years: An update of a Cochrane systematic review and meta-analysis including studies from 2015-2021.', EClinicalMedicine, 54 101635 (2022) [C1]
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Nova |
2022 |
Moore THM, Phillips S, Hodder RK, O'Brien KM, Hillier-Brown F, Dawson S, et al., 'Interventions to prevent obesity in children aged 2 to 4 years old', Cochrane Database of Systematic Reviews, 2022 (2022)
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. The overall aim of the review is to determine the effectiveness of interventio... [more]
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. The overall aim of the review is to determine the effectiveness of interventions to prevent obesity in two- to four-year-old children. The four objectives are:. 1. to evaluate the effects of interventions that aim to modify dietary intake on changes in zBMI score, BMI and serious adverse events among children;. 2. to evaluate the effects of interventions that aim to modify physical activity, sedentary behaviour, sleep, play or structured exercise or a combination of these on changes in zBMI score, BMI and serious adverse events among children;. 3. to evaluate the combined effects of interventions that aim to modify both dietary intake and physical activity/movement behaviours on changes in zBMI score, BMI and serious adverse events among children;. 4. to compare the effects of interventions that aim to modify dietary interventions with those that aim to modify physical activity/movement behaviours on changes in zBMI score, BMI and serious adverse events among children. The secondary objectives are designed to explore if, how, and why the effectiveness of interventions on zBMI/BMI varies depending on the following PROGRESS factors. Place of residence Race/ethnicity/culture/language Occupation Gender/sex Religion Education Socioeconomic status Social capital. The PROGRESS acronym is intended to ensure that there is explicit consideration for health inequity, the unfair difference in disease burden, when conducting research and adapting research evidence to inform the design of new interventions (O'Neill 2014). The PROGRESS acronym describes factors that contribute to health inequity. Recent work on race and religion in the UK suggests that consideration of these factors is critical to the design of new interventions (Rai 2019). We will also collect, from RCTs, information about the costs of interventions, so that policymakers can use the review as a source of information from which they may prepare cost-effectiveness analyses.
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2021 |
Hall A, O'Brien K, McCrabb S, Kypri K, Brown S, Wilczynska M, et al., 'Learnings from efforts to synthesise evidence on the COVID-19 incubation period', PUBLIC HEALTH, 198 E12-E13 (2021)
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2021 |
O'Brien KM, Barnes C, Yoong S, Campbell E, Wyse R, Delaney T, et al., 'School-Based Nutrition Interventions in Children Aged 6 to 18 Years: An Umbrella Review of Systematic Reviews', NUTRIENTS, 13 (2021) [C1]
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Nova |
2021 |
Delaney T, McLaughlin M, Hall A, Yoong SL, Brown A, O brien K, et al., 'Associations between digital health intervention engagement and dietary intake: A systematic review', Nutrients, 13 (2021) [C1]
There has been a proliferation of digital health interventions (DHIs) targeting dietary in-take. Despite their potential, the effectiveness of DHIs are thought to be dependent, in... [more]
There has been a proliferation of digital health interventions (DHIs) targeting dietary in-take. Despite their potential, the effectiveness of DHIs are thought to be dependent, in part, on user engagement. However, the relationship between engagement and the effectiveness of dietary DHIs is not well understood. The aim of this review is to describe the association between DHI engagement and dietary intake. A systematic search of four electronic databases and grey literature for records published before December 2019 was conducted. Studies were eligible if they examined a quantitative association between objective measures of engagement with a DHI (subjective experience or usage) and measures of dietary intake in adults (aged = 18 years). From 10,653 citations, seven studies were included. Five studies included usage measures of engagement and two examined subjective experiences. Narrative synthesis, using vote counting, found mixed evidence of an association with usage measures (5 of 12 associations indicated a positive relationship, 7 were in-conclusive) and no evidence regarding an association with subjective experience (both studies were inconclusive). The findings provide early evidence supporting an association between measures of usage and dietary intake; however, this was inconsistent. Further research examining the association between DHI engagement and dietary intake is warranted.
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Nova |
2020 |
Robson EK, Hodder RK, Kamper SJ, O'Brien KM, Williams A, Lee H, et al., 'Effectiveness of weight-loss interventions for reducing pain and disability in people with common musculoskeletal disorders: A systematic review with meta-analysis', Journal of Orthopaedic and Sports Physical Therapy, 50 319-333 (2020) [C1]
Objective: To assess the effectiveness of weight-loss interventions on pain and disability in people with knee and hip osteoarthritis (OA) and spinal pain. Design: Intervention sy... [more]
Objective: To assess the effectiveness of weight-loss interventions on pain and disability in people with knee and hip osteoarthritis (OA) and spinal pain. Design: Intervention systematic review. Literature Search: Twelve online databases and clinical trial registries. Study Selection Criteria: Randomized controlled trials of any weight-loss intervention (eg, diet, physical activity, surgical, pharmaceutical) that reported pain or disability outcomes in people with knee or hip OA or spinal pain. Data Synthesis: We calculated mean differences or standardized mean differences (SMDs) and 95% confidence intervals (CIs). We used the Cochrane risk of bias tool to assess risk of bias and the Grading of Recommendations Assessment, Development, and Evaluation tool to judge credibility of evidence. Results: Twenty-two trials with 3602 participants were included. There was very low- to very low-credibility evidence for a moderate effect of weight-loss interventions on pain intensity (10 trials, n = 1806; SMD, -0.54; 95% CI: -0.86, -0.22; I2 = 87%, P<.001) and a small effect on disability (11 trials, n = 1821; SMD, -0.32; 95% CI: -0.49, -0.14; I2 = 58%, P <.001) compared to minimal care for people with OA. For knee OA, there was low- to moderate-credibility evidence that weight-loss interventions were not more effective than exercise only for pain intensity and disability, respectively (4 trials, n = 673; SMD, -0.13; 95% CI: -0.40, 0.14; I2 = 55%; 5 trials, n = 737; SMD, -0.20; 95% CI: -0.41, 0.00; I2 = 32%). Conclusion: Weight-loss interventions may provide small to moderate improvements in pain and disability for OA compared to minimal care. There was limited and inconclusive evidence for weight-loss interventions targeting spinal pain.
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Nova |
2020 |
Hodder RK, O'Brien KM, Tzelepis F, Wyse RJ, Wolfenden L, 'Interventions for increasing fruit and vegetable consumption in children aged five years and under', COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (2020) [C1]
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Nova |
2019 |
Hodder RK, O'Brien KM, Stacey FG, Tzelepis F, Wyse RJ, Bartlem KM, et al., 'Interventions for increasing fruit and vegetable consumption in children aged five years and under', Cochrane Database of Systematic Reviews, 2019 (2019) [C1]
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Nova |
2019 |
Williams A, van Dongen JM, Kamper SJ, O'Brien KM, Wolfenden L, Yoong SL, et al., 'Economic evaluation of a healthy lifestyle intervention for chronic low back pain: A randomized controlled trial', European Journal of Pain (United Kingdom), 23 621-634 (2019) [C1]
Background: Economic evaluations which estimate cost-effectiveness of potential treatments can guide decisions about real-world healthcare services. We performed an economic evalu... [more]
Background: Economic evaluations which estimate cost-effectiveness of potential treatments can guide decisions about real-world healthcare services. We performed an economic evaluation of a healthy lifestyle intervention targeting weight loss, physical activity and diet for patients with chronic low back pain, who are overweight or obese. Methods: Eligible patients with chronic low back pain (n¿=¿160) were randomized to an intervention or usual care control group. The intervention included brief advice, a clinical consultation and referral to a 6-month telephone-based healthy lifestyle coaching service. The primary outcome was quality-adjusted life years (QALYs). Secondary outcomes were pain intensity, disability, weight and body mass index. Costs included intervention costs, healthcare utilization costs and work absenteeism costs. An economic analysis was performed from the societal perspective. Results: Mean total costs were lower in the intervention group than the control group (-$614; 95%CI: -3133 to 255). The intervention group had significantly lower healthcare costs (-$292; 95%CI: -872 to -33), medication costs (-$30; 95%CI: -65 to -4) and absenteeism costs (-$1,000; 95%CI: -3573 to -210). For all outcomes, the intervention was on average less expensive and more effective than usual care, and the probability of the intervention being cost-effective compared to usual care was relatively high (i.e., 0.81) at a willingness-to-pay of $0/unit of effect. However, the probability of cost-effectiveness was not as favourable among sensitivity analyses. Conclusions: The healthy lifestyle intervention seems to be cost-effective from the societal perspective. However, variability in the sensitivity analyses indicates caution is needed when interpreting these findings. Significance: This is an economic evaluation of a randomized controlled trial of a healthy lifestyle intervention for chronic low back pain. The findings suggest that a healthy lifestyle intervention may be cost-effective relative to usual care.
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Nova |
2019 |
Robson E, Kamper S, Saragiotto B, Williams C, O'Brien K, Williams A, et al., 'ECONOMIC EVALUATION OFA HEALTH BEHAVIOUR INTERVENTION FOR MUSCULOSKELETAL CONDITIONS (vol 25, pg 1, 2018)', INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE, 26 102-103 (2019)
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2019 |
Kamper S, Williams A, Lee H, O'Brien K, Wiggers J, Yoong SL, et al., 'CAUSAL MECHANISMS OF A HEALTH BEHAVIOUR INTERVENTION FOR PATIENTS WITH MUSCULOSKELETAL PAIN (vol 25, pg 1, 2018)', INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE, 26 103-104 (2019)
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2019 |
Williams A, Lee H, Kamper SJ, O Brien KM, Wiggers J, Wolfenden L, et al., 'Causal mechanisms of a healthy lifestyle intervention for patients with musculoskeletal pain who are overweight or obese', Clinical Rehabilitation, 33 1088-1097 (2019) [C1]
Purpose: To assess the causal mechanisms of a healthy lifestyle intervention for patients with chronic low back pain and knee osteoarthritis, who are overweight or obese. Methods:... [more]
Purpose: To assess the causal mechanisms of a healthy lifestyle intervention for patients with chronic low back pain and knee osteoarthritis, who are overweight or obese. Methods: We conducted causal mediation analyses of aggregated data from two randomized controlled trials (RCTs); which included 160 patients with chronic low back pain, and 120 patients with knee osteoarthritis. The intervention consisted of brief advice and referral to a six-month telephone-based healthy lifestyle coaching service. We used causal mediation to estimate the indirect, direct and path-specific effects of hypothesized mediators including: self-reported weight, diet, physical activity, and pain beliefs. Outcomes were pain intensity, disability, and quality of life (QoL). Results: The intervention did not reduce weight, improve diet or physical activity or change pain beliefs, and these mediators were not associated with the outcomes. Sensitivity analyses showed that our estimates were robust to the possible effects of unknown and unmeasured confounding. Conclusions: Our findings show that the intervention did not cause a meaningful change in the hypothesized mediators, and these mediators were not associated with patient-reported outcomes.
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Nova |
2019 |
Williams A, Kamper S, Wiggers J, O'Brien K, Lee H, Wolfenden L, et al., 'DO MUSCULOSKELETAL CONDITIONS INCREASE THE RISK OF CHRONIC DISEASE: A SYSTEMATIC REVIEWAND META- ANALYSIS OF COHORT STUDIES (vol 25, pg 1, 2018)', INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE, 26 114-114 (2019)
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2018 |
Hodder RK, Stacey FG, O'Brien KM, Wyse RJ, Clinton-McHarg T, Tzelepis F, et al., 'Interventions for increasing fruit and vegetable consumption in children aged five years and under', COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (2018)
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2018 |
O'Brien KM, Hodder RK, Wiggers J, Williams A, Campbell E, Wolfenden L, et al., 'Effectiveness of telephone-based interventions for managing osteoarthritis and spinal pain: a systematic review and meta-analysis', PEERJ, 6 (2018) [C1]
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Nova |
2018 |
O'Brien KM, Wiggers J, Williams A, Campbell E, Hodder RK, Wolfenden L, et al., 'Telephone-based weight loss support for patients with knee osteoarthritis: a pragmatic randomised controlled trial', Osteoarthritis and Cartilage, 26 485-494 (2018) [C1]
Objective: To determine the effectiveness of telephone-based weight loss support in reducing the intensity of knee pain in patients with knee osteoarthritis, who are overweight or... [more]
Objective: To determine the effectiveness of telephone-based weight loss support in reducing the intensity of knee pain in patients with knee osteoarthritis, who are overweight or obese, compared to usual care. Design: We conducted a parallel randomised controlled trial (RCT), embedded within a cohort multiple RCT of patients on a waiting list for outpatient orthopaedic consultation at a tertiary referral hospital in NSW, Australia. Patients with knee osteoarthritis, classified as overweight or obese [body mass index (BMI) between =27 kg/m2 and <40 kg/m2] were randomly allocated to receive referral to an existing non-disease specific government funded 6-month telephone-based weight management and healthy lifestyle service or usual care. The primary outcome was knee pain intensity measured using an 11-point numerical rating scale (NRS) over 6-month follow-up. A number of secondary outcomes, including self-reported weight were measured. Data analysis was by intention-to-treat according to a pre-published analysis plan. Results: Between May 19 and June 30 2015, 120 patients were randomly assigned to the intervention (59 analysed, one post-randomisation exclusion) or usual care (60 analysed). We found no statistically significant between group differences in pain intensity [area under the curve (AUC), mean difference 5.4, 95%CI: -13.7 to 24.5, P = 0.58] or weight change at 6 months (self-reported; mean difference -0.4, 95%CI: -2.6 to 1.8, P = 0.74). Conclusions: Among patients with knee osteoarthritis who are overweight, telephone-based weight loss support, provided using an existing 6-month weight management and healthy lifestyle service did not reduce knee pain intensity or weight, compared with usual care. Trial registration number: ACTRN12615000490572
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Nova |
2018 |
Hodder RK, O'Brien KM, Stacey FG, Wyse RJ, Clinton-McHarg T, Tzelepis F, et al., 'Interventions for increasing fruit and vegetable consumption in children aged five years and under (Review)', COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (2018) [C1]
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Nova |
2018 |
Williams A, Wiggers J, O'Brien KM, Wolfenden L, Yoong SL, Hodder RK, et al., 'Effectiveness of a healthy lifestyle intervention for chronic low back pain: a randomised controlled trial.', Pain, 159 1137-1146 (2018) [C1]
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Nova |
2018 |
Williams A, Kamper SJ, Wiggers JH, O'Brien KM, Lee H, Wolfenden L, et al., 'Musculoskeletal conditions may increase the risk of chronic disease: A systematic review and meta-analysis of cohort studies', BMC Medicine, 16 (2018) [C1]
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Nova |
2018 |
O'Brien KM, van Dongen JM, Williams A, Kamper SJ, Wiggers J, Hodder RK, et al., 'Economic evaluation of telephone-based weight loss support for patients with knee osteoarthritis: a randomised controlled trial', BMC PUBLIC HEALTH, 18 (2018) [C1]
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Nova |
2017 |
Hodder RK, Stacey FG, Wyse RJ, O'Brien KM, Clinton-McHarg T, Tzelepis F, et al., 'Interventions for increasing fruit and vegetable consumption in children aged five years and under', COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (2017) [C1]
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Nova |
2017 |
Hodder RK, Wolfenden L, Kamper SJ, Lee H, Williams A, O'Brien KM, Williams CM, 'Developing implementation science to improve the translation of research to address low back pain: A critical review', Best Practice and Research: Clinical Rheumatology, 30 1050-1073 (2017) [C1]
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Nova |
2017 |
Lee H, Wiggers J, Kamper SJ, Williams A, O'Brien KM, Hodder RK, et al., 'Mechanism evaluation of a lifestyle intervention for patients with musculoskeletal pain who are overweight or obese: protocol for a causal mediation analysis', BMJ OPEN, 7 (2017)
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Nova |
2016 |
O'Brien KM, Wiggers J, Williams A, Campbell E, Wolfenden L, Yoong S, et al., 'Randomised controlled trial of referral to a telephone-based weight management and healthy lifestyle programme for patients with knee osteoarthritis who are overweight or obese: a study protocol', BMJ OPEN, 6 (2016)
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2016 |
Williams A, Wiggers J, O'Brien KM, Wolfenden L, Yoong S, Campbell E, et al., 'A randomised controlled trial of a lifestyle behavioural intervention for patients with low back pain, who are overweight or obese: study protocol', BMC MUSCULOSKELETAL DISORDERS, 17 (2016)
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Nova |
2016 |
O Brien KM, Williams A, Wiggers J, Wolfenden L, Yoong S, Campbell E, et al., 'Effectiveness of a healthy lifestyle intervention for low back pain and osteoarthritis of the knee: Protocol and statistical analysis plan for two randomised controlled trials', Brazilian Journal of Physical Therapy, 20 477-489 (2016)
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Nova |
2014 |
O'Brien KM, Hutchesson MJ, Jensen M, Morgan P, Callister R, Collins CE, 'Participants in an online weight loss program can improve diet quality during weight loss: a randomized controlled trial.', Nutrition journal, 13 82 (2014) [C1]
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Nova |
2010 |
Goodman-Delahunty J, Cossins A, O'Brien K, 'Enhancing the Credibility of Complainants in Child Sexual Assault Trials: The Effect of Expert Evidence and Judicial Directions', BEHAVIORAL SCIENCES & THE LAW, 28 769-783 (2010)
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