Research
The Centre for Reproductive Science strives to tackle key challenges in reproductive health, including infertility, reproductive disorders, and complications during pregnancy.
Through pioneering research, we aim to develop new treatments, diagnostic tools, and interventions that enhance fertility and reproductive success. Our work spans both human health and the wellbeing of animals that are vital to ecosystems and economies.
Research themes
Discovery research
The Discovery Research theme investigates the fundamental molecular, cellular, and physiological processes that underpin reproduction and fertility. Our projects reveal new insights into sperm function beyond fertilisation, the influence of seminal fluid signals on conception, and the role of the epididymis in shaping fertility and offspring health. We explore how environmental exposures affect reproductive outcomes across generations, and pioneer technologies to track RNA dynamics, restore male fertility, and deliver targeted therapies for reproductive and endocrine disease. This theme builds the foundational knowledge needed to transform understanding and treatment of reproductive health challenges.
Theme leaders: John Schjenken, Tessa Lord
Applied clinical
The Applied Clinical theme translates fundamental discoveries into innovative diagnostics and therapies that improve reproductive outcomes in humans. Our research addresses the biological causes of male infertility, advancing new strategies to enhance sperm function and conception success. Clinical trials evaluate novel interventions, such as scrotal cooling devices to counteract testicular heat stress and restore sperm quality. Strong industry collaborations drive the development of technologies including the Felix™ sperm separation device, oxidative stress diagnostics, and specialised sperm storage media. By integrating discovery science with clinical application, this theme delivers tangible solutions to the global burden of infertility.
Theme leaders: Geoff De Iuliis, R. John Aitken
Applied veterinary
The Applied Veterinary theme develops innovative reproductive technologies to advance animal breeding, health, and welfare. Our research addresses critical challenges in the equine and livestock industries, including early pregnancy detection in mares through immune and molecular biomarkers, and the creation of rapid, on-farm diagnostic assays. We have delivered novel industry-adopted sperm preservation media, portable fertility diagnostics, and tools to monitor reproductive function. By combining discovery science with practical application, this theme provides transformative solutions that improve breeding efficiency, genetic gain, and sustainability, while supporting the economic and welfare priorities of animal industries.
Theme leaders: Zamira Gibb, Aleona Swegen
Conservation
The Conservation theme harnesses reproductive science to protect biodiversity and safeguard endangered species. Research in this area develops assisted reproductive technologies, biobanking strategies, and diagnostic tools to preserve genetic diversity and improve breeding outcomes in wildlife populations. By integrating cellular, molecular, and ecological approaches, this theme addresses the challenges posed by climate change, disease, and habitat loss, while building capacity for sustainable conservation programs.
Theme leaders: Rose Upton, Brett Nixon
The University of Newcastle acknowledges the traditional custodians of the lands within our footprint areas: Awabakal, Darkinjung, Biripai, Worimi, Wonnarua, and Eora Nations. We also pay respect to the wisdom of our Elders past and present.