Dr John Schjenken

Dr John Schjenken

Reseach Associate

School of Environmental and Life Sciences

Career Summary

Biography

Biography

I am a post-doctoral research fellow in the Priority Research Centre for Reproductive Science. My research interests and expertise are primarily focused on defining the physiological importance of the female immune response to conception, and the significance of the male ejaculate in the reproductive process.

I studied a Bachelor of Science (Biotechnology) at the University Of Newcastle, Australia. Following completion of this degree in 2004, I began work in the field of reproductive biology (2005-current) where my research has focused on both male and female reproductive biology. This research has ranged from cytochrome P450 enzymes and their expression in mouse male germ cells during spermatogenesis (Honours – Reproductive Science Group – Priority Research Centre for Reproductive Science – Supervisor: Dr Shaun Roman) to understanding the potential immunological role of human endogenous retroviral envelope proteins that are expressed in the placenta and secreted in small nanovesicles called exosomes (PhD – Mothers and Babies Research Centre – Priority Research Centre for Reproductive Science – Supervisors: Prof Roger Smith and Prof Vicki Clifton). In 2010, I had the opportunity to begin post-doctoral studies at the Robinson Research Institute, University of Adelaide. Here I joined the lab of Professor Sarah Robertson and was responsible for research projects that contribute to the understanding of the physiological importance of the female immune response to conception, and the significance of the male ejaculate (seminal fluid) in the reproductive process. 

In May 2019, I had the exciting opportunity to return to the Priority Research Centre for Reproductive Science at the University of Newcastle, in the laboratory of Professor Brett Nixon where I am establishing a reproductive immunology research program within the centre, while maintaining close collaborations with Professor Sarah Robertson at the University of Adelaide. This program is focused on building knowledge on paternal contributions to the events around conception, with particular interest in understanding the synthesis and source of immune regulatory factors carried by the male ejaculate, which have substantial influence for female immune adaptation to pregnancy. A comprehensive understanding of seminal fluid function can further out understanding of causes of infertility, miscarriage and pregnancy disorders, and how both maternal and paternal contributions can contribute to the health of the child after birth.

My current areas of research interest include:

  1. Examining the impact of environmental exposures on seminal fluid immune regulatory factor synthesis.
  2. Building knowledge of the significance of seminal fluid extracellular vesicles in female immune regulatory function.

Qualifications

  • Doctor of Philosophy, University of Newcastle

Keywords

  • Immunology
  • Reproductive Biology

Languages

  • English (Mother)

Fields of Research

Code Description Percentage
111499 Paediatrics and Reproductive Medicine not elsewhere classified 50
060199 Biochemistry and Cell Biology not elsewhere classified 20
110799 Immunology not elsewhere classified 30

Professional Experience

UON Appointment

Title Organisation / Department

Academic appointment

Dates Title Organisation / Department
1/1/2018 - 31/12/2019 Research Associate

In 2018, I was promoted to Academic level B at the Robinson Research Institute, University of Adelaide in the laboratory of Professor Sarah Robertson. Here, I began research in the broad area of immunology of reproduction which continues to shaper my research interests. I undertook research that aimed to define the molecular mechanisms that regulate the female reproductive tract response to seminal fluid, identify novel seminal fluid signalling mediators and determine the impact of these mediators on pregnancy quality and offspring health.

The University of Adelaide
Robinson Research Institute and Adelaide Medical School
Australia
10/5/2010 - 31/12/2017 Research Associate

In May 2010, I obtained a post-doctoral position at the Robinson Research Institute, University of Adelaide in the laboratory of Professor Sarah Robertson. Here, I began research in the broad area of immunology of reproduction which continues to shaper my research interests. I undertook research that aimed to define the molecular mechanisms that regulate the female reproductive tract response to seminal fluid, identify novel seminal fluid signalling mediators and determine the impact of these mediators on pregnancy quality and offspring health.

The University of Adelaide
Robinson Research Institute and Adelaide Medical School
Australia

Awards

Award

Year Award
2019 Society for Reproductive Biology 2019 - Finalist in SRB Newcastle Reproduction Emerging Research Leader Award
Society for Reproductive Biology
2017 Epigenetics Consortium of South Australia Incorporated (EpiCSA) - Robinson Research Institute Award for Best Epigenetic Oral Presentation in Reproduction
Epigenetics Consortium of South Australia Incorporated (EpiCSA)
2016 Epigenetics Consortium of South Australia Incorporated (EpiCSA) - Best Early Career Researcher Oral
Epigenetics Consortium of South Australia Incorporated (EpiCSA)
2016 Epigenetics Consortium of South Australia Incorporated (EpiCSA) - Best Robinson Research Institute Speaker
Epigenetics Consortium of South Australia Incorporated (EpiCSA)
2016 Epigenetics Consortium of South Australia Incorporated (EpiCSA) - People's Choice Award
Epigenetics Consortium of South Australia Incorporated (EpiCSA)
2016 Robinson Research Institute Symposium 2016 - Best Early Career Researcher Poster presentation
The University of Adelaide
2015 Robinson Research Institute Symposium 2015 - Best ECR oral
The University of Adelaide
2014 Society for the Study of Reproduction 2014 - International Best Abstract Award representing Australia.
Society for the Study of Reproduction
2013 Robinson Institute Symposium - Best ECR Poster Award
The University of Adelaide

Invitations

Speaker

Year Title / Rationale
2019 Obesity Alters Seminal Vesicle Fluid Composition and Signaling Capacity in Mice
2018 What’s the man got to do with it?
2017 Paternal environment and male: female seminal fluid signalling.
2017 Paternal environment and male: female seminal fluid signalling.
2017 miRNA-155 is required to induce competent regulatory T cells and to protect against inflammation-induced fetal loss in mice.
2016 Seminal fluid regulation of microRNAs in the peri-conception immune environment and role in pregnancy success
2016 Sperm signalling in the female reproductive tract of mammals: Implications for Reproductive Success
2016 Seminal Fluid Signalling and the Trajectory for Healthy Pregnancy
2015 Novel mechanisms for Seminal Fluid Signalling in Reproduction
2015 miRNA regulation of immune responses at conception
2014 Regulation of the female tract response to seminal fluid by miRNA-223
2013 Sperm Mediated Signalling in the Female Reproductive Tract of the Mouse

Teaching

Code Course Role Duration
HLTH SC 1005 HLTH SC 1005 - Principles of Human Health and Disease
The University of Adelaide
Guest lecture 7/11/2018 - 8/11/2018
BIOL2002 BIOL2002 Laboratory Skills in Biological Systems
Faculty of Science and Information Technology The University of Newcastle
Lecturer and demonstrator 26/8/2019 - 18/9/2019
OB&GYNAE3100 Research Project in Reproductive Health
The University of Adelaide
Guest lecture 5/8/2015 - 15/8/2017
OB&GYNAE3000 OB&GYNAE 3000 - Human Reproductive Health III
The University of Adelaide
Guest lecturer 4/9/2014 - 4/9/2018
BIOL3001 BIOL3001 Advanced Laboratory Skills in Biological Sciences
Faculty of Science and Information Technology The University of Newcastle
Lecturer and demonstrator 13/5/2019 - 31/5/2019
3BH066 Honours Degree of Bachelor of Health and Medical Sciences
The University of Adelaide
Guest lecture 5/3/2014 - 5/3/2016
BTEC3200 Cellular Biotechnology
Faculty of Science and Information Technology The University of Newcastle

Guest lecture 9/9/2019 - 10/9/2019
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Publications

For publications that are currently unpublished or in-press, details are shown in italics.


Chapter (6 outputs)

Year Citation Altmetrics Link
2018 Schjenken JE, Sharkey DJ, Robertson SA, 'Seminal vesicle Secretion', Encyclopaedia of Reproduction Second Edition, Elsevier, Oxford, UK 349-353 (2018)
DOI 10.1016/B978-0-12-801238-3.64600-7
2016 Fullston T, Shehadeh H, Schjenken JE, McPherson NO, Robertson SA, Zander-Fox D, Lane M, 'Paternal Obesity and Programming of Offspring Health', Parental Obesity: Intergenerational Programming and Consequences, Springer, New York 105-131 (2016)
DOI 10.1007/978-1-4939-6386-7
2015 Robertson SA, Chin P-Y, Schjenken JE, Thompson JG, 'Female Tract Cytokines and Developmental Programming in Embryos', CELL SIGNALING DURING MAMMALIAN EARLY EMBRYO DEVELOPMENT, SPRINGER-VERLAG BERLIN 173-213 (2015)
DOI 10.1007/978-1-4939-2480-6_7
Citations Scopus - 22Web of Science - 19
2015 Schjenken JE, Robertson SA, 'Seminal Fluid Signalling in the Female Reproductive Tract: Implications for Reproductive Success and Offspring Health', MALE ROLE IN PREGNANCY LOSS AND EMBRYO IMPLANTATION FAILURE, SPRINGER-VERLAG BERLIN 127-158 (2015)
DOI 10.1007/978-3-319-18881-2_6
Citations Scopus - 31Web of Science - 29
2013 Robertson SA, Sharkey DJ, Schjenken JE, Care AS, Moldenhauer LM, 'Pathways for activating implantation tolerance in early pregnancy.', Immunology of Pregnancy 2013, Bentham Science Publishers, United Arab Emirates 1835-1874 (2013)
DOI 10.1016/B978-0-12-397175-3.00041-7
2012 Schjenken JE, Tolosa Gonzalez JM, Paul JW, Clifton VL, Smith R, 'Mechanisms of maternal immune tolerance during pregnancy', Recent Advances in Research on the Human Placenta, InTech, Rijeka, Croatia 211-242 (2012) [B1]
Co-authors Roger Smith, Jonathan Paul
Show 3 more chapters

Journal article (23 outputs)

Year Citation Altmetrics Link
2020 McCarron A, Cmielewski P, Reyne N, McIntyre C, Finnie J, Craig F, et al., 'Phenotypic characterization and comparison of Phe508del and cystic fibrosis transmembrane conductance regulator (CFTR) knockout rat models of cystic fibrosis generated by CRISPR/Cas9 gene editing.', Am J Pathol, (2020)
DOI 10.1016/j.ajpath.2020.01.009
2020 McCarron A, Cmielewski P, Reyne N, McIntyre C, Finnie J, Craig F, et al., 'Phenotypic characterisation and comparison of Phe508del and CFTR knockout rat models of cystic fibrosis generated by CRISPR/Cas9 gene editing', American Journal of Pathology, (2020)
2020 Schjenken JE, Robertson SA, 'The female response to seminal fluid', Physiological Reviews, (2020)
2020 Schjenken JE, Moldenhauer LM, Zhang B, Care AS, Groome HM, Chan H-Y, et al., 'MicroRNA miR-155 is required for expansion of regulatory T cells to mediate robust pregnancy tolerance in mice', Mucosal Immunology, (2020)
DOI 10.1038/s41385-020-0255-0
2019 Schjenken JE, Panir K, Robertson SA, Hull ML, 'Exosome-mediated intracellular signalling impacts the development of endometriosis-new avenues for endometriosis research', MOLECULAR HUMAN REPRODUCTION, 25 2-4 (2019)
DOI 10.1093/molehr/gay050
Citations Scopus - 2Web of Science - 1
2019 Kedzior SGE, Bianco-Miotto T, Breen J, Diener KR, Donnelley M, Dunning KR, et al., 'It takes a community to conceive: an analysis of the scope, nature and accuracy of online sources of health information for couples trying to conceive', Reproductive Biomedicine and Society Online, 9 48-63 (2019) [C1]
DOI 10.1016/j.rbms.2019.08.004
2019 Moldenhauer LM, Schjenken JE, Hope CM, Green ES, Zhang B, Eldi P, et al., 'Thymus-Derived Regulatory T Cells Exhibit Foxp3 Epigenetic Modification and Phenotype Attenuation after Mating in Mice', JOURNAL OF IMMUNOLOGY, 203 647-657 (2019)
DOI 10.4049/jimmunol.1900084
Citations Scopus - 1Web of Science - 1
2018 Sharkey DJ, Glynn DJ, Schjenken JE, Tremellen KP, Robertson SA, 'Interferon-gamma inhibits seminal plasma induction of colony-stimulating factor 2 in mouse and human reproductive tract epithelial cells', BIOLOGY OF REPRODUCTION, 99 514-526 (2018)
DOI 10.1093/biolre/ioy071
Citations Scopus - 7Web of Science - 7
2018 Panir K, Schjenken JE, Robertson SA, Hull ML, 'Non-coding RNAs in endometriosis: a narrative review', HUMAN REPRODUCTION UPDATE, 24 497-515 (2018)
DOI 10.1093/humupd/dmy014
Citations Scopus - 24Web of Science - 23
2018 Sadlon T, Brown CY, Bandara V, Hope CM, Schjenken JE, Pederson SM, et al., 'Unravelling the molecular basis for regulatory T-cell plasticity and loss of function in disease', CLINICAL & TRANSLATIONAL IMMUNOLOGY, 7 (2018)
DOI 10.1002/cti2.1011
Citations Scopus - 6Web of Science - 5
2017 Akison LK, Andraweera PH, Bertoldo MJ, Brown HM, Cuffe JSM, Fullston T, et al., 'The current state of reproductive biology research in Australia and New Zealand: core themes from the Society for Reproductive Biology Annual Meeting, 2016', REPRODUCTION FERTILITY AND DEVELOPMENT, 29 1883-1889 (2017)
DOI 10.1071/RD16382
2017 Robertson SA, Zhang B, Chan H, Sharkey DJ, Barry SC, Fullston T, Schjenken JE, 'MicroRNA regulation of immune events at conception', MOLECULAR REPRODUCTION AND DEVELOPMENT, 84 914-925 (2017)
DOI 10.1002/mrd.22823
Citations Scopus - 7Web of Science - 6
2016 Schjenken JE, Zhang B, Chan HY, Sharkey DJ, Fullston T, Robertson SA, 'miRNA Regulation of Immune Tolerance in Early Pregnancy', AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 75 272-280 (2016)
DOI 10.1111/aji.12490
Citations Scopus - 18Web of Science - 16
2016 Dickinson H, Moss TJ, Gatford KL, Moritz KM, Akison L, Fullston T, et al., 'A review of fundamental principles for animal models of DOHaD research: an Australian perspective', JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE, 7 449-472 (2016)
DOI 10.1017/S2040174416000477
Citations Scopus - 45Web of Science - 47
2015 Schjenken JE, Glynn DJ, Sharkey DJ, Robertson SA, 'TLR4 Signaling Is a Major Mediator of the Female Tract Response to Seminal Fluid in Mice', BIOLOGY OF REPRODUCTION, 93 (2015)
DOI 10.1095/biolreprod.114.125740
Citations Scopus - 30Web of Science - 19
2015 Prins JR, Zhang B, Schjenken JE, Guerin LR, Barry SC, Robertson SA, 'Unstable Foxp3(+) Regulatory T Cells and Altered Dendritic Cells Are Associated with Lipopolysaccharide-Induced Fetal Loss in Pregnant Interleukin 10-Deficient Mice', BIOLOGY OF REPRODUCTION, 93 (2015)
DOI 10.1095/biolreprod.115.128694
Citations Scopus - 15Web of Science - 14
2015 Sharkey DJ, Schjenken JE, Mottershead DG, Robertson SA, 'Seminal fluid factors regulate activin A and follistatin synthesis in female cervical epithelial cells', MOLECULAR AND CELLULAR ENDOCRINOLOGY, 417 178-190 (2015)
DOI 10.1016/j.mce.2015.09.022
Citations Scopus - 8Web of Science - 8
2014 Nixon BJ, Katen AL, Stanger SJ, Schjenken JE, Nixon B, Roman SD, 'Mouse spermatocytes express CYP2E1 and respond to acrylamide exposure', PLoS ONE, 9 (2014) [C1]

Metabolism of xenobiotics by cytochrome P450s (encoded by the CYP genes) often leads to bio-activation, producing reactive metabolites that interfere with cellular processes and c... [more]

Metabolism of xenobiotics by cytochrome P450s (encoded by the CYP genes) often leads to bio-activation, producing reactive metabolites that interfere with cellular processes and cause DNA damage. In the testes, DNA damage induced by xenobiotics has been associated with impaired spermatogenesis and adverse effects on reproductive health. We previously reported that chronic exposure to the reproductive toxicant, acrylamide, produced high levels of DNA damage in spermatocytes of Swiss mice. CYP2E1 metabolises acrylamide to glycidamide, which, unlike acrylamide, readily forms adducts with DNA. Thus, to investigate the mechanisms of acrylamide toxicity in mouse male germ cells, we examined the expression of the CYP, CYP2E1, which metabolises acrylamide. Using Q-PCR and immunohistochemistry, we establish that CYP2E1 is expressed in germ cells, in particular in spermatocytes. Additionally, CYP2E1 gene expression was upregulated in these cells following in vitro acrylamide exposure (1 µM, 18 h). Spermatocytes were isolated and treated with 1 µM acrylamide or 0.5 µM glycidamide for 18 hours and the presence of DNA-adducts was investigated using the comet assay, modified to detect DNA-adducts. Both compounds produced significant levels of DNA damage in spermatocytes, with a greater response observed following glycidamide exposure. A modified comet assay indicated that direct adduction of DNA by glycidamide was a major source of DNA damage. Oxidative stress played a small role in eliciting this damage, as a relatively modest effect was found in a comet assay modified to detect oxidative adducts following glycidamide exposure, and glutathione levels remained unchanged following treatment with either compound. Our results indicate that the male germ line has the capacity to respond to xenobiotic exposure by inducing detoxifying enzymes, and the DNA damage elicited by acrylamide in male germ cells is likely due to the formation of glycidamide adducts. © 2014 Nixon et al.

DOI 10.1371/journal.pone.0094904
Citations Scopus - 18Web of Science - 16
Co-authors Shaun Roman, Brett Nixon
2014 Bromfield JJ, Schjenken JE, Chin PY, Care AS, Jasper MJ, Robertson SA, 'Maternal tract factors contribute to paternal seminal fluid impact on metabolic phenotype in offspring', PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111 2200-2205 (2014)
DOI 10.1073/pnas.1305609111
Citations Scopus - 180Web of Science - 169
2014 Schjenken JE, Robertson SA, 'Seminal Fluid and Immune Adaptation for Pregnancy - Comparative Biology in Mammalian Species', REPRODUCTION IN DOMESTIC ANIMALS, 49 27-36 (2014)
DOI 10.1111/rda.12383
Citations Scopus - 47Web of Science - 45
2013 Fung KY, Mangan NE, Cumming H, Horvat JC, Mayall JR, Stifter SA, et al., 'Interferon-epsilon Protects the Female Reproductive Tract from Viral and Bacterial Infection', SCIENCE, 339 1088-1092 (2013) [C1]
DOI 10.1126/science.1233321
Citations Scopus - 110Web of Science - 110
Co-authors Jay Horvat, Philip Hansbro
2012 Tolosa Gonzalez JM, Schjenken JE, Clifton VL, Vargas A, Barbeau B, Lowry P, et al., 'The endogenous retroviral envelope protein syncytin-1 inhibits LPS/PHA-stimulated cytokine responses in human blood and is sorted into placental exosomes', Placenta, 33 933-941 (2012) [C1]
Citations Scopus - 62Web of Science - 56
Co-authors Roger Smith, Kaushik Maiti
2007 Tolosa Gonzalez JM, Schjenken JE, Civiti TD, Clifton VL, Smith R, 'Column-based method to simultaneously extract DNA, RNA, and proteins from the same sample', Biotechniques, 43 799-804 (2007) [C1]
DOI 10.2144/000112594
Citations Scopus - 34Web of Science - 28
Co-authors Roger Smith
Show 20 more journal articles
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Grants and Funding

Summary

Number of grants 10
Total funding $876,305

Click on a grant title below to expand the full details for that specific grant.


20192 grants / $435,000

Vevo 3100 ultrasound biomicroscope for the Adelaide Biomed city precinct$360,000

Funding body: Ian Potter Foundation

Funding body Ian Potter Foundation
Scheme Ian Potter Foundation
Role Investigator
Funding Start 2019
Funding Finish 2019
GNo
Type Of Funding Not Known
Category UNKN
UON N

Deletion of a noncoding region regulating SATB1 cause infertility in mice: A novel model of unexplained infertility in women$75,000

Funding body: Women's and Children's Hospital Foundation

Funding body Women's and Children's Hospital Foundation
Project Team

Prof Simon Barry, Dr Tim Sadlon, Prof Sarah Robertson and Dr John Schjenken

Scheme WCH Foundation - Project Grant
Role Investigator
Funding Start 2019
Funding Finish 2020
GNo
Type Of Funding Not Known
Category UNKN
UON N

20181 grants / $73,445

Impact of Phthalate exposure in fathers on programming of offspring neurological phenotype$73,445

Funding body: Channel 7 Children's Research Foundation of South Australia

Funding body Channel 7 Children's Research Foundation of South Australia
Project Team

Prof Sarah Robertson, Dr John Schjenken, Dr Lachlan Moldenhauer, Dr David Sharkey, Prof Emilie Rissman

Scheme Project Grant
Role Investigator
Funding Start 2018
Funding Finish 2019
GNo
Type Of Funding Not Known
Category UNKN
UON N

20172 grants / $261,360

Boosting Treg cells with novel immune-regulatory agents for pregnancy success $210,000

Funding body: Ferring Pharmaceuticals

Funding body Ferring Pharmaceuticals
Project Team

Prof Sarah Robertson, Dr David Sharkey, Dr Lachlan Moldenhauer

Scheme Ferring Pharmaceuticals
Role Investigator
Funding Start 2017
Funding Finish 2019
GNo
Type Of Funding Not Known
Category UNKN
UON N

Impact of Phthalate exposures on paternal programming of offspring neurological phenotype $51,360

Funding body: CHHE Pilot Project Program (supported in part by NIEHS under award number P30ES025128)

Funding body CHHE Pilot Project Program (supported in part by NIEHS under award number P30ES025128)
Project Team

Prof Emilie Rissman, Dr John Schjenken and Prof Sarah Robertson

Scheme CHHE Pilot Project Program (supported in part by NIEHS under award number P30ES025128)
Role Investigator
Funding Start 2017
Funding Finish 2017
GNo
Type Of Funding Not Known
Category UNKN
UON N

20162 grants / $50,000

In vivo functional validation of a disease linked super enhancer in IBD$25,000

Funding body: Robinson Research Institute

Funding body Robinson Research Institute
Project Team

Dr Tim Sadlon and Dr John Schjenken

Scheme Robinson Research Institute Seed Funding Grant
Role Investigator
Funding Start 2016
Funding Finish 2016
GNo
Type Of Funding Internal
Category INTE
UON N

The conception of a preconception resource-#rightmessage #rightaudience #righttime #conceptionhealthmatters.$25,000

Funding body: Robinson Research Institute

Funding body Robinson Research Institute
Project Team

Sophie G.E. Kedzior, Tina Bianco-Miotto, James Breen, Kerrilyn R. Diener, Martin Donnelley, Kylie R. Dunning, Megan A.S. Penno, John E. Schjenken, David J. Sharkey, Nicolette A. Hodyl, Tod Fullston, Maria Gardiner, Hannah M. Brown, Alice R. Rumbold

Scheme Robinson Research Institute Engaging Opportunities Program
Role Investigator
Funding Start 2016
Funding Finish 2016
GNo
Type Of Funding Internal
Category INTE
UON N

20151 grants / $30,000

Perturbation of Seminal Fluid Signalling in the Female Reproductive Tract in a Mouse Model of Paternal Obesity$30,000

Funding body: Robinson Research Institute

Funding body Robinson Research Institute
Project Team

Dr John Schjenken and Dr Tod Fullston

Scheme Robinson Research Institute Seed Funding Grant
Role Lead
Funding Start 2015
Funding Finish 2015
GNo
Type Of Funding Internal
Category INTE
UON N

20142 grants / $26,500

The role of distal regulatory elements in setting SATB1 expression levels in Tregs: implications in autoimmune disease and maternal immune tolerance to the fetus$25,000

Funding body: Robinson Research Institute

Funding body Robinson Research Institute
Project Team

Dr Tim Sadlon and Dr John Schjenken

Scheme Robinson Research Institute Seed Funding Grant
Role Investigator
Funding Start 2014
Funding Finish 2014
GNo
Type Of Funding Internal
Category INTE
UON N

Evolution of Seminal Fluid Signalling Mechanisms in Mammals$1,500

Funding body: Australian Society for Reproductive Biology

Funding body Australian Society for Reproductive Biology
Project Team

Dr John Schjenken and Dr Brandon Menzies

Scheme Early Career Researcher Collaborative Research Travel Award
Role Lead
Funding Start 2014
Funding Finish 2014
GNo
Type Of Funding Not Known
Category UNKN
UON N
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Research Supervision

Number of supervisions

Completed9
Current5

Current Supervision

Commenced Level of Study Research Title Program Supervisor Type
2020 PhD Exploring ALOX15 as a Molecular Conduit between Infertility and Systemic Ill Health in Men PhD (Biological Sciences), Faculty of Science, The University of Newcastle Co-Supervisor
2020 PhD Novel Roles for Seminal Fluid Extracellular Vesicles PhD (Biological Sciences), Faculty of Science, The University of Newcastle Principal Supervisor
2019 PhD Investigations of Early Pregnancy in the Mare using novel in vitro modeling techniques PhD (Biological Sciences), Faculty of Science, The University of Newcastle Co-Supervisor
2019 PhD Investigating the impact of deleting a disease linked super-enhancer on SATB1 expression and function in the T cell compartment Paediatrics, The University of Adelaide Co-Supervisor
2015 PhD Impact of Seminal Fluid on Peri-Conception Cytokine Expression and Postnatal Development Obstetrics & Gynaecology, The University of Adelaide Co-Supervisor

Past Supervision

Year Level of Study Research Title Program Supervisor Type
2019 Honours The impact of paternal phthalate exposure on reproductive and offspring health Obstetrics & Gynaecology, The University of Adelaide Principal Supervisor
2019 PhD The contribution of immune regulatory MicroRNAs in endometriosis Obstetrics & Gynaecology, The University of Adelaide Co-Supervisor
2019 Masters Using RNA-Seq to Investigate the Contribution of miRNA-223 & miRNA-155 to Endometriosis Lesion Development Biological Sciences, The University of Adelaide Co-Supervisor
2018 Honours The role of seminal fluid beta-defensin 22 in induction of maternal fetal immune tolerance Biological Sciences, The University of Adelaide Co-Supervisor
2018 Honours Does the SATBI superenhancer prevent autoimmunity in mice? Biological Sciences, The University of Adelaide Co-Supervisor
2018 Honours The effect of miR-223 in a syngeneic mouse model of endometriosis Obstetrics & Gynaecology, The University of Adelaide Co-Supervisor
2017 PhD T Regulatory Cells in Early Pregnancy in Mice Obstetrics & Gynaecology, The University of Adelaide Co-Supervisor
2014 Honours The role of miR-146a in the peri-conceptional period of early pregnancy Obstetrics & Gynaecology, The University of Adelaide Co-Supervisor
2012 Honours The Impact of Seminal Fluid and miRNA on the Immune Cell Pool During Early Pregnancy Obstetrics & Gynaecology, The University of Adelaide Co-Supervisor
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Dr John Schjenken

Position

Reseach Associate
School of Environmental and Life Sciences
Faculty of Science

Contact Details

Email john.schjenken@newcastle.edu.au
Link Twitter
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