2022 |
Murphy VE, Jensen ME, Holliday EG, Giles WB, Barrett HL, Callaway LK, et al., 'Effect of asthma management with exhaled nitric oxide
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Nova |
2021 |
Ferini-Strambi L, Hensley M, Salsone M, 'Decoding Causal Links Between Sleep Apnea and Alzheimer's Disease', JOURNAL OF ALZHEIMERS DISEASE, 80 29-40 (2021) [C1]
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Nova |
2021 |
Sforza M, Galbiati A, Zucconi M, Casoni F, Hensley M, Ferini-Strambi L, Castronovo V, 'Depressive and stress symptoms in insomnia patients predict group cognitive-behavioral therapy for insomnia long-term effectiveness: A data-driven analysis.', JOURNAL OF AFFECTIVE DISORDERS, 289 117-124 (2021) [C1]
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Nova |
2021 |
Mitchell I, Lacey J, Anstey M, Corbett C, Douglas C, Drummond C, et al., 'Understanding end-of-life care in Australian hospitals', AUSTRALIAN HEALTH REVIEW, 45 540-547 (2021) [C1]
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Nova |
2021 |
van Rotterdam F-J, Hensley M, Hazelton M, 'Measuring Change in Health Status Over Time (Responsiveness): A Meta-analysis of the SF-36 in Cardiac and Pulmonary Rehabilitation.', Archives of rehabilitation research and clinical translation, 3 100127 (2021) [C1]
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Nova |
2019 |
Van Rotterdam J, Hensley M, Hazelton M, 'A Comparative Effectiveness Review: RESPONSIVENESS OF PATIENT OUTCOME MEASURES IN CARDIAC AND PULMONARY REHABILITATION', Journal of Cardiopulmonary Rehabilitation and Prevention, 39 73-84 (2019) [C1]
Background: Cardiac and pulmonary rehabilitation have been shown to reduce the symptoms of disease, as well as reducing health care utilization. To ensure the continuation of thes... [more]
Background: Cardiac and pulmonary rehabilitation have been shown to reduce the symptoms of disease, as well as reducing health care utilization. To ensure the continuation of these programs, patient outcome measures (POMs) are essential to map treatment effectiveness. This review is a comparative effectiveness literature review of studies with a pre- to post-POM assessment of responsiveness (ie, change in health status over time). Methods: A quality review of the literature included not only randomized controlled trials but also parallel studies, as well as all observational and retrospective trials. This review included a list of articles and their characteristics; a quality assessment of the literature and a list of POMs utilized in this setting were assessed for responsiveness. Results: There was inconsistency in the literature with the measurement of responsiveness or effect size. The most commonly used POM was the SF-36; however, it was found to be less responsive to change in health status pre- to post-rehabilitation, particularly in the mental domain of this instrument. The most responsive POM in this setting was the Global Mood Scale. Conclusion: The surveyed literature found no "gold standard" POM for either cardiac rehabilitation or pulmonary rehabilitation but there was some preference for the disease-specific POMs; however, some of these instruments lose their discriminatory power at the end of the rehabilitation period. This literature review found that a Likert scale is more responsive than a dichotomous scale and that a simple questionnaire is more responsive in a pre- to post-setting than a complex questionnaire.
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Nova |
2019 |
Kochovska S, Fazekas B, Hensley M, Wheatley J, Allcroft P, Currow DC, 'A Randomized, Double-Blind, Multisite, Pilot, Placebo-Controlled Trial of Regular, Low-Dose Morphine on Outcomes of Pulmonary Rehabilitation in COPD', JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 58 E7-E9 (2019)
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2019 |
Chu G, Suthers B, Moores L, Paech GM, Hensley MJ, McDonald VM, Choi P, 'Risk factors of sleep-disordered breathing in haemodialysis patients', PLOS ONE, 14 (2019) [C1]
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Nova |
2018 |
Suthers B, Pradeepan S, Yates N, Hensley M, Eckert D, 'FIXED VERSUS AUTOMATIC POSITIVE AIRWAY PRESSURE THERAPY FOR POSITIONAL OBSTRUCTIVE SLEEP APNOEA-A DOUBLE-BLIND, RANDOMISED TRIAL', SLEEP, 41 A209-A210 (2018) |
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2018 |
Duncan MJ, Brown WJ, Burrows TL, Collins CE, Fenton S, Glozier N, et al., 'Examining the efficacy of a multicomponent m-Health physical activity, diet and sleep intervention for weight loss in overweight and obese adults: randomised controlled trial protocol', BMJ OPEN, 8 (2018)
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2018 |
Castronovo V, Galbiati A, Sforza M, Poletti M, Giarolli L, Kuo T, et al., 'Long-term clinical effect of group cognitive behavioral therapy for insomnia: a case series study', SLEEP MEDICINE, 47 54-59 (2018) [C1]
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2018 |
Galbiati A, Carli G, Hensley M, Ferini-Strambi L, 'REM Sleep Behavior Disorder and Alzheimer's Disease: Definitely No Relationship?', JOURNAL OF ALZHEIMERS DISEASE, 63 1-11 (2018)
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2017 |
Martinez FE, Anstey M, Ford A, Roberts B, Hardie M, Palmer R, et al., 'Prophylactic Melatonin for Delirium in Intensive Care (Pro-MEDIC): study protocol for a randomised controlled trial', TRIALS, 18 (2017)
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2017 |
McLoughlin RF, McDonald VM, Gibson PG, Scott HA, Hensley MJ, MacDonald-Wicks L, Wood LG, 'The Impact of a Weight Loss Intervention on Diet Quality and Eating Behaviours in People with Obesity and COPD.', Nutrients, 9 1-14 (2017) [C1]
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Nova |
2016 |
Paul C, Rose S, Hensley M, Pretto J, Hardy M, Henskens F, et al., 'Examining uptake of online education on obstructive sleep apnoea in general practitioners: A randomised trial', BMC Research Notes, 9 (2016) [C1]
Background: Obstructive sleep apnoea (OSA) affects up to 28 % of the adult population in Western countries. The detection and management of OSA by general practitioners (GPs) can ... [more]
Background: Obstructive sleep apnoea (OSA) affects up to 28 % of the adult population in Western countries. The detection and management of OSA by general practitioners (GPs) can be poor. The study aimed to examine what influence enhanced invitations had on uptake of on-line learning modules for OSA by GPs, and whether recent referrals of patients to sleep specialists influenced uptake. Methods: Practicing GPs in regional Australia were identified and randomised to receive either an enhanced or standard invitation letter to a new on-line education module for OSA. The enhanced letter included indication that the module was eligible for professional accreditation and described the prevalence and burden of sleep disorders. Some included extra emphasis if the GP had recently referred a patient for diagnostic investigation of OSA. Two reminder letters were sent. Results: Of 796 eligible GPs who received the letters, sixteen (2 %) accessed the website and four completed the modules over the four-month study period. GPs who received an enhanced invitation letter were not significantly more likely to access the website compared to GPs who received the standard invitation letter. Recent referral of a patient for diagnostic investigation was also not a significant factor in influencing use of the module. Conclusion: GP interest in on-line education about OSA appears low, and emphasis of relevant recent past patient(s) and the opportunity for professional education points was not successful in increasing engagement. There is a need to identify effective approaches to improving the detection and management of OSA in general practice.
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Nova |
2016 |
Murphy VE, Jensen ME, Mattes J, Hensley MJ, Giles WB, Peek MJ, et al., 'The Breathing for Life Trial: a randomised controlled trial of fractional exhaled nitric oxide (FENO)-based management of asthma during pregnancy and its impact on perinatal outcomes and infant and childhood respiratory health', BMC PREGNANCY AND CHILDBIRTH, 16 (2016)
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Nova |
2016 |
Rose S, Pretto J, Paul C, Emmett B, Hensley M, Henskens F, 'Relationships between nutritional knowledge, obesity, and sleep disorder severity', Journal of Sleep Research, 25 350-355 (2016) [C1]
Obstructive sleep apnea affects 20% of the adult population. Weight control is considered the best non-medical means of managing the condition, therefore improving nutritional kno... [more]
Obstructive sleep apnea affects 20% of the adult population. Weight control is considered the best non-medical means of managing the condition, therefore improving nutritional knowledge in individuals may be an appropriate strategy. This study aimed to describe the relationship between nutritional knowledge and: (i) sleep disorder severity; (ii) body mass index; and (iii) demographic characteristics in persons suspected of obstructive sleep apnea. Nutrition knowledge scores were also compared with the general population. Consecutive newly-referred patients attending the sleep laboratory for diagnostic polysomnography were invited to participate. Those who consented (n = 97) were asked to complete a touchscreen survey. Apnea-hypopnea index to measure sleep disorder severity and anthropometric measurements were obtained from the clinic. A quarter of participants were diagnosed with severe obstructive sleep apnea; and a majority (88%) were classed as being overweight or obese. The overall mean nutrition knowledge score was 58.4 ± 11.6 (out of 93). Nutrition knowledge was not associated with sleep disorder severity, body mass index or gender. The only significant difference detected was in relation to age, with older (=35 years) participants demonstrating greater knowledge in the 'food choices' domain compared with their younger counterparts (18-34 years; P < 0.030). Knowledge scores were similar to the general population. The findings suggest that nutrition knowledge alone is not an important target for weight control interventions for people with obstructive sleep apnea. However, given the complexities of sleep disorders, it may complement other strategies.
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Nova |
2016 |
McDonald VM, Gibson PG, Scott HA, Baines PJ, Hensley MJ, Pretto JJ, Wood LG, 'Should we treat obesity in COPD? The effects of diet and resistance exercise training', Respirology, 21 875-882 (2016) [C1]
Background and objective: Obesity is an established risk factor for poor health outcomes, but paradoxically in chronic obstructive pulmonary disease (COPD), it is associated with ... [more]
Background and objective: Obesity is an established risk factor for poor health outcomes, but paradoxically in chronic obstructive pulmonary disease (COPD), it is associated with improved survival and lung function. A major evidence gap exisits to inform treatment recommendations for patients with COPD who are obese. We aimed to determine the effect of weight reduction involving a low-energy diet utilizing a partial meal replacement plan, coupled with resistance exercise training in obese COPD patients. Methods: In a proof of concept before¿after clinical trial, obese (body mass index =30 kg/m2) COPD patients received a 12 week weight reduction programme involving meal replacements, dietary counselling by a dietitian and resistance exercise training prescribed and supervised by a physiotherapist. Patients were reviewed face to face by the dietitian and physiotherapist every 2 weeks for counselling. Results: Twenty-eight participants completed the intervention. Mean (standard deviation) body mass index was 36.3 kg/m2 (4.6) at baseline and reduced by 2.4 kg/m2 ((1.1) P < 0.0001) after the intervention. Importantly, skeletal muscle mass was maintained. Clinical outcomes improved with weight loss including exercise capacity, health status, dyspnea, strength and functional outcomes. There was also a significant reduction in the body mass index, obstruction, dyspnea and exercise score (BODE). Systemic inflammation measured by C-reactive protein however did not change. Conclusion: In obese COPD patients, dietary energy restriction coupled with resistance exercise training results in clinically significant improvements in body mass index, exercise tolerance and health status, whilst preserving skeletal muscle mass. This novel study provides a framework for development of guidelines for the management of obese COPD patients and in guiding future research.
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Nova |
2015 |
Powell H, Murphy VE, Hensley MJ, Giles W, Clifton VL, Gibson PG, 'Rhinitis in pregnant women with asthma is associated with poorer asthma control and quality of life', Journal of Asthma, (2015) [C1]
© 2015 Taylor & Francis. Objective: To describe the pattern and severity of rhinitis in pregnancy and the impact rhinitis has on asthma control and quality of life (QoL) in pr... [more]
© 2015 Taylor & Francis. Objective: To describe the pattern and severity of rhinitis in pregnancy and the impact rhinitis has on asthma control and quality of life (QoL) in pregnant women with asthma. Methods: Two hundred and eighteen non-smoking pregnant women with asthma were participants in a randomised controlled trial of exhaled nitric oxide guided treatment adjustment. Rhinitis was assessed using a visual analogue scale (VAS) scored from 0 to 10 and classified as current (VAS¿>¿2.5), moderate/severe versus mild (VAS¿>¿6 vs <5), atopic versus non-atopic and pregnancy rhinitis. At baseline, women completed the 20-Item Sino-Nasal Outcome Test (SNOT20), asthma-specific (AQLQ-M) QoL questionnaires and the Six-Item Short-Form State Trait Anxiety Inventory (STAI-6). Asthma control was assessed using the asthma control questionnaire (ACQ). Perinatal outcomes were collected after delivery. Results: Current rhinitis was present in 142 (65%) women including 45 (20%) women who developed pregnancy rhinitis. Women with current rhinitis had higher scores for ACQ (p¿=¿0.004), SNOT20 (p¿<¿0.0001) and AQLQ-M (p¿<¿0.0001) compared to women with no rhinitis. Current rhinitis was associated with increased anxiety symptoms (p¿=¿0.002), rhinitis severity was associated with higher ACQ score (p¿=¿0.004) and atopic rhinitis was associated with poorer lung function (p¿=¿0.037). Rhinitis symptom severity improved significantly during gestation (p¿<¿0.0001). There was no impact on perinatal outcomes. Improved asthma control was associated with improvement in rhinitis. Conclusion: Rhinitis in pregnant women with asthma is common and associated with poorer asthma control, sino-nasal and asthma-specific QoL impairment and anxiety. In the context of active asthma management there was significant improvement in rhinitis symptoms and severity as pregnancy progressed.
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Nova |
2013 |
Rose S, Emmett B, Paul C, Hensley M, Henskens FA, Pretto J, 'Relationships between nutrition knowledge, obesity and severity of sleep-disordered breathing', Sleep and Biological Rhythm, 11 1-78 (2013)
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2013 |
Pretto JJ, Brazzale DJ, Guy PA, Goudge RJ, Hensley MJ, 'Reasons for Referral for Pulmonary Function Testing: An Audit of 4 Adult Lung Function Laboratories', RESPIRATORY CARE, 58 507-510 (2013) [C1]
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Nova |
2013 |
Powell H, McCaffery K, Murphy VE, Hensley MJ, Clifton VL, Giles W, Gibson PG, 'Psychosocial Variables Are Related to Future Exacerbation Risk and Perinatal Outcomes in Pregnant Women with Asthma', JOURNAL OF ASTHMA, 50 383-389 (2013) [C1]
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Nova |
2013 |
Rose S, Emmett B, Pretto J, Hensley M, Henskens FA, Tindall K, Paul C, 'Accuracy of questionnaire-based measures for predicting sleep disoriented breathing', Sleep and Biological Rhythms, 11 1-78 (2013)
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2013 |
Gyulay S, Pretto J, Hensley M, 'A systematic approach to selecting starting pressure results in better sleep outcomes from CPAP titration studies', EUROPEAN RESPIRATORY JOURNAL, 42 (2013) |
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2012 |
Nair BR, Hensley MJ, Parvathy MSD, Lloyd DM, Murphy B, Ingham K, et al., 'A systematic approach to workplace-based assessment for international medical graduates', Medical Journal of Australia, 196 399-402 (2012) [C1]
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Nova |
2012 |
Pretto JJ, Guy PA, Brazzale DJ, Hensley MJ, 'REASONS FOR REFERRAL FOR PULMONARY FUNCTION TESTING: AN AUDIT OF FOUR ADULT LUNG FUNCTION LABORATORIES', RESPIROLOGY, 17 83-83 (2012) [E3] |
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2012 |
Pretto JJ, McDonald VM, Wark PA, Hensley MJ, 'Multicentre audit of inpatient management of acute exacerbations of chronic obstructive pulmonary disease: Comparison with clinical guidelines', Internal Medicine Journal, 42 380-387 (2012) [C1]
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2011 |
Powell GH, Murphy VE, Taylor DR, Hensley MJ, McCaffery K, Giles W, et al., 'Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: A double-blind, randomised controlled trial', The Lancet, 378 983-990 (2011) [C1]
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Nova |
2011 |
Antic NA, Catcheside P, Buchan C, Hensley MJ, Naughton MT, Rowland S, et al., 'The effect of CPAP in normalizing daytime sleepiness, quality of life, and neurocognitive function in patients with moderate to severe OSA', Sleep, 34 111-119 (2011) [C1]
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Nova |
2011 |
Powell H, McCaffery K, Murphy VE, Hensley MJ, Clifton VL, Giles WB, Gibson PG, 'Psychosocial outcomes are related to asthma control and quality of life in pregnant women with asthma', Journal of Asthma, 48 1032-1040 (2011) [C1]
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Nova |
2011 |
Wood LG, Powell H, Grissell TV, Davies BL, Shafren DR, Whitehead BF, et al., 'Persistence of rhinovirus RNA and IP-10 gene expression after acute asthma', Respirology, 16 291-299 (2011) [C1]
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Nova |
2010 |
Hensley MJ, Ray CD, 'Sleep Apnea', American Family Physician, 81 195-196 (2010) [C3]
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2010 |
Pretto JJ, Gyulay SG, Hensley MJ, 'Trends in anthropometry and severity of sleep-disordered breathing over two decades of diagnostic sleep studies in an Australian adult sleep laboratory', Medical Journal of Australia, 193 213-216 (2010) [C1]
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Nova |
2009 |
Hensley M, Ray C, 'Sleep apnoea', BMJ clinical evidence, 2009 (2009)
INTRODUCTION: Sleep apnoea is the popular term for obstructive sleep apnoea-hypopnoea syndrome (OSAHS). OSAHS is abnormal breathing during sleep that causes recurrent arousals, sl... [more]
INTRODUCTION: Sleep apnoea is the popular term for obstructive sleep apnoea-hypopnoea syndrome (OSAHS). OSAHS is abnormal breathing during sleep that causes recurrent arousals, sleep fragmentation, excessive daytime sleepiness, and nocturnal hypoxaemia. Apnoea may be "central", in which there is cessation of inspiratory effort, or "obstructive", in which inspiratory efforts continue but are ineffective because of upper airway obstruction. OSAHS affects up to 4% of men and 2% of women in the USA, with obesity being a major determinant.
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2009 |
Miles S, Rogers KM, Thomas P, Soans B, Attia JR, Abel C, et al., 'A comparison of single-photon emission CT lung scintigraphy and CT pulmonary angiography for the diagnosis of pulmonary embolism', Chest, 136 1546-1553 (2009) [C1]
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Nova |
2009 |
Antic NA, Buchan C, Esterman A, Hensley MJ, Naughton MT, Rowland S, et al., 'A randomized controlled trial of nurse-led care for symptomatic moderate-severe obstructive sleep apnea', American Journal of Respiratory and Critical Care Medicine, 179 501-508 (2009) [C1]
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Nova |
2009 |
Simonella L, O'Connell DL, Vinod SK, Delaney GP, Boyer M, Esmaili N, et al., 'No improvement in lung cancer care: The management of lung cancer in 1996 and 2002 in New South Wales', Internal Medicine Journal, 39 453-458 (2009) [C1]
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Nova |
2008 |
Powell H, Smart JM, Wood LG, Grissell TV, Shafren DR, Hensley MJ, Gibson PG, 'Validity of the common cold questionnaire (CCQ) in asthma exacerbations', PLoS ONE, 3 e1802 (2008) [C1]
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Nova |
2007 |
Harris B, Bailey D, Miles S, Bailey E, Rogers K, Roach P, et al., 'Objective analysis of tomographic ventilation-perfusion scintigraphy in pulmonary embolism', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 175 1173-1180 (2007)
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2007 |
Harris B, Bailey D, Miles S, Bailey E, Rogers K, Roach P, et al., 'Objective analysis of tomographic ventilation-perfusion scintigraphy in pulmonary embolism', American Journal of Respiratory and Critical Care Medicine, 175 1173-1180 (2007) [C1]
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2007 |
Gibson PG, Abramson M, Wood-Baker R, Volmink J, Hensley M, Costabel U, 'Evidence-based Respiratory Medicine', Evidence-based Respiratory Medicine, 1-593 (2007)
First major evidence-based text in adult respiratory medicine. Comprehensive, authoritative summary of the best treatments for the major respiratory diseases. Compiled by speciali... [more]
First major evidence-based text in adult respiratory medicine. Comprehensive, authoritative summary of the best treatments for the major respiratory diseases. Compiled by specialists from the Cochrane Airways Management Group. Easy-to-use format, with key clinical implications summarised in each chapter. Kept up-to-date online: Compiled by specialists from the Cochrane Collaboration Airways Management Group, Evidence-based Respiratory Medicine is the first major evidence-based text in adult respiratory medicine. Providing a comprehensive summary of the best treatments for the most important respiratory diseases, some of the world's leading physicians review the evidence for a broad range of treatments using evidence-based principles. Essential information is presented in an easy-to-understand format, with the most important clinical implications summarised in each chapter. Evidence-based Respiratory Medicine tackles the big clinical questions in diagnosis and treatment, presenting treatment options which take into account the individual patient's needs. Evidence-Based Series:Evidence-based Respiratory Medicine, part of the acclaimed series BMJ Evidence-based medicine textbooks that have revolutionised clinical medicine literature, comes with a fully searchable CD-ROM of the whole text. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file. © 2005 by Blackwell Publishing Ltd.
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2007 |
Wood LG, Powell HG, Grissell TV, Nguyen TTD, Shafren D, Hensley MJ, Gibson PG, 'Persistent airway obstruction after virus infection is not associated with airway inflammation', Chest, 131 415-423 (2007) [C1]
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2007 |
Durrheim DN, Hensley MJ, 'Should medical students be routinely offered BCG vaccination? (Letter)', Medical Journal of Australia, 186 98-99 (2007) [C3]
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2006 |
Tiong LU, Davies R, Gibson PG, Hensley MJ, Hepworth R, Lasserson TJ, Smith B, 'Lung volume reduction surgery for diffuse emphysema.', Cochrane database of systematic reviews (Online), (2006)
BACKGROUND: Lung volume reduction surgery (LVRS) has been re-introduced for treating patients with severe diffuse emphysema. It is a procedure that aims to improve long-term daily... [more]
BACKGROUND: Lung volume reduction surgery (LVRS) has been re-introduced for treating patients with severe diffuse emphysema. It is a procedure that aims to improve long-term daily functioning, although it is costly and may also be associated with a high risk of mortality. OBJECTIVES: To assemble evidence from randomised controlled trials for the effectiveness of LVRS, and identify optimal surgical techniques. SEARCH STRATEGY: Randomised controlled trials were identified using the Cochrane Airways Group Chronic Obstructive Pulmonary Disease (COPD) register. Searches are current to September 2005. SELECTION CRITERIA: Randomised controlled trials that studied the safety and efficacy of LVRS in patients with diffuse emphysema were included. Studies were excluded if they investigated giant or bullous emphysema. DATA COLLECTION AND ANALYSIS: Two independent review authors assessed trials for inclusion and extracted data. Where possible, data from more than one study were combined using RevMan 4.2 software. MAIN RESULTS: Eight studies (1663 participants) met the entry criteria of the review. One study accounted for 73% of the participants recruited. Study quality was high, although blinding in studies was not possible. Ninety day mortality was significantly greater in all those who underwent LVRS (odds ratio 6.57 (95% CI 3.34 to 12.95), four studies, N = 1415). A subgroup analysis by risk status suggested that there was a subgroup of participants who were consistently at a significant risk of death, although this was only measured in one large study. The ninety day mortality data indicated that death was more likely with LVRS irrespective of risk status identified in one large study. Improvements in lung function, quality of life and exercise capacity were more likely with LVRS than with usual follow-up. AUTHORS' CONCLUSIONS: The evidence summarised in this review is drawn from one large study, and several smaller trials. The findings from the large study indicated that in patients who survive up to three months post-surgery, there were significantly better health status and lung function outcomes in favour of surgery compared with usual medical care. Patients identified post hoc as being of high risk of death from surgery were those with particularly impaired lung function and poor diffusing capacity and/or homogenous emphysema. Further research should address the effect of this intervention on exacerbations and rate of decline in lung function and health status.
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2006 |
Tiong LU, Davies HRHR, Gibson PG, Hensley MJ, Hepworth R, Lasserson TJ, Smith B, 'Lung volume reduction surgery for diffuse emphysema', COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (2006)
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2005 |
Grissell TV, Powell H, Shafren DR, Boyle MJ, Hensley MJ, Jones PD, et al., 'Interleukin-10 gene expression in acute virus-induced asthma', American Journal of Respiratory and Critical Care Medicine, 172 433-439 (2005) [C1]
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Nova |
2005 |
Nagle AL, Hensley MJ, Schofield MJ, Koschel AJ, 'A randomised controlled trial to evaluate the efficacy of a nurse-provided intervention for hospitalised smokers', Australian and New Zealand Journal of Public Health, 29 285-291 (2005) [C1]
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Nova |
2004 |
Hensley M, Ray C, 'Sleep apnoea.', Clinical evidence, 2401-2415 (2004)
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2004 |
Rodsutti J, Hensley M, Thakkinstian A, D'Este C, Attia J, 'A clinical decision rule to prioritize polysomnography in patients with suspected sleep apnea', SLEEP, 27 694-699 (2004) [C1]
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2004 |
Rodsutti J, Thakkinstian A, Hensley MJ, D'Este CA, Attia JR, 'A clinical decision rule to prioritise polysomnography in patients with suspected sleep apnoea', Sleep, 27 694-699 (2004) [C2]
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2004 |
Vinod SK, Hui AC, Esmaili N, Hensley MJ, Barton MB, 'Comparison of patterns of care in lung cancer in three area health services in New South Wales, Australia', Internal Medicine Journal, 34 677-683 (2004) [C1]
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2003 |
Hensley MJ, Chalmers AC, Clover K, Gibson PG, Toneguzzi R, Lewis PR, 'Symptoms of Asthma: Comparison of a Parent-Completed Retrospective Questionnaire With a Prospective Daily Symptom Diary', Pediatric Pulmonology, 36 509-513 (2003) [C1]
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2003 |
Hensley M, Ray C, 'Sleep apnoea.', Clinical evidence, 1958-1974 (2003)
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2003 |
Hensley M, Ray C, 'Sleep apnoea.', Clinical evidence, 1958-1974 (2003) |
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2003 |
Castronovo V, Zucconi M, Nosetti L, Marazzini C, Hensley MJ, Veglia F, et al., 'Prevalence of habitual snoring and sleep-disordered breathing in preschool-aged children in an Italian community', the Journal of Pediatrics, 142 377-382 (2003) [C1]
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Nova |
2003 |
Wark PA, Hensley MJ, Saltos N, Boyle MJ, Toneguzzi R, Simpson JL, et al., 'Anti-inflammatory effect of itraconazole in stable allergic bronchopulmonary aspergillosis: A randomized controlled trial', The Journal of Allergy and Clinical Immunology, 111 952-957 (2003) [C1]
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2002 |
Wark PA, Johnston S, Simpson JL, Hensley MJ, Gibson PG, 'Chlamydia pneumoniae immunoglobulin A reactivation and airway inflammation in acute asthma', The European Respiratory Journal, 20 834-840 (2002) [C1]
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2002 |
Wark PA, Johnston S, Moric I, Simpson JL, Hensley MJ, Gibson PG, 'Neutrophil degranulation and cell lysis is associated with clinical severity in virus-induced asthma', The European Respiratory Journal, 19 68-75 (2002) [C1]
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2002 |
Wark PA, Simpson JL, Hensley MJ, Gibson PG, 'Airway inflammation in thunderstorm asthma', Clinical and Experimental Allergy, 32 1750-1756 (2002) [C1]
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2002 |
Hensley MJ, 'Sleep apnoea (obstructive sleep apnoea-hypopnoea syndrome)', Clinical Evidence, 7 1566-1578 (2002) [C3]
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2002 |
Gibson PG, Coughlan J, Wilson A, Hensley MJ, Abramson M, Bauman A, Walters E, 'Limited (information only) patient education programs for adults with asthma', The Cochrane Library, 2 CD001005 (2002) [C3]
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Nova |
2002 |
Gibson PG, Powell H, Wilson A, Hensley MJ, Abramson MJ, Bauman A, et al., 'Limited (information only) patient education programs for adults with asthma', Cochrane Database of Systematic Reviews, 2010 (2002)
Background: A key component of many asthma management guidelines is the recommendation for patient education and regular medical review. A number of controlled trials have been co... [more]
Background: A key component of many asthma management guidelines is the recommendation for patient education and regular medical review. A number of controlled trials have been conducted to measure the effectiveness of asthma education programmes. These programmes improve patient knowledge, but their impact on health outcomes is less well established. At its simplest level, education is limited to the transfer of information about asthma, its causes and its treatment. This review focused on the effects of limited asthma education. Objectives: The objective of this review was to assess the effects of limited (i.e. information only) asthma education on health outcomes in adults with asthma. Search methods: We searched the Cochrane Airways Group trials register and reference lists of articles. Selection criteria: Randomised and controlled trials of individual asthma education involving information transfer only in adults over 16 years of age. Data collection and analysis: Trial quality was assessed and two reviewers extracted data independently. Study authors were contacted for missing information. Main results: Twelve trials were included. They were of variable quality. Limited asthma education did not reduce hospitalisation for asthma (weighted mean difference -0.03 average hospitalisations per person per year, 95% confidence interval -0.09 to 0.03). There was no significant effect on doctor visits, lung function and medication use. The effects on asthma symptoms were variable. There was no reduction in days lost from normal activity, but in two studies, perceived asthma symptoms did improve after limited asthma education (odds ratio 0.44, 95% confidence interval 0.26 to 0.74). In one study, limited asthma education was associated with reduced emergency department visits (reduction of -2.76 average visits per person per year, 95% confidence interval -4.34 to 1.18). Authors' conclusions: Use of limited asthma education as it has been practiced does not appear to improve health outcomes in adults with asthma although perceived symptoms may improve. Provision of information in the emergency department may be effective, but this needs to be confirmed.
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2001 |
Wark PA, Simpson J, Hensley MJ, Gibson PG, 'Safety of sputum induction with isotonic saline in adults with acute severe asthma', Clinical and Experimental Allergy, 31 1745-1753 (2001) [C1]
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2001 |
Gibson PG, Simpson J, Chalmers AC, Toneguzzi R, Wark PA, Wilson AJ, Hensley MJ, 'Airway Eosinophilia is associated with Wheeze but is uncommon in Children with Persistent Cough and Frequent Chest Colds', American Journal of Respiratory and Critical Care Medicine, 164 977-981 (2001) [C1]
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Nova |
2001 |
Wild KL, Carless R, Hensley MJ, Rowley M, Pab W, 'The application of a ward based clinical pathway to facilitate the introduction of bi level positive airway pressure (bipap) in acute respiratory failure in copd', Respirology, 6 (2001)
The efficacy of BiPAP in acute respiratory failure in chronic obstructive pulmonary disease (COPD) is established, but challenges remain in introducing this into clinical practice... [more]
The efficacy of BiPAP in acute respiratory failure in chronic obstructive pulmonary disease (COPD) is established, but challenges remain in introducing this into clinical practice. To facilitate this we devised a clinical pathway (CP) that combines treatment from intensive care and the respiratory ward. The aim of this study was to assess our ability to implement BiPAP treatment via this CP. Method: A retrospective case controlled study was undertaken. Consecutive subjects presenting with acute hypercapnoeic respiratory failure secondary to COPD were commenced on the BiPAP clinical pathway (n=17). They were compared to controls matched according to sex, age and severity of acute and chronic respiratory disease (n=34). Results: Only 1 subject treated with BiPAP needed to be intubated compared to 20 controls (p<0.01). The BiPAP group spent a mean of 22.9 hours in the ICU compared with 104 hours for the controls (pO.OOl), and had a mean length of stay in hospital of 7.9 days compared to 12.6 days in the controls (p=0.01). There was 1 death in the Bi PAP group and 7 in the control group (p=0.2). Conclusion: The introduction of BiPAP treatment through a CP has resulted in a significant improvement in patient outcomes and length of stay.
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2000 |
Olson LG, Coughlan J, Rolfe I, Hensley MJ, 'THE EFFECT OF A STRUCTURED QUESTION GRID ON THE VALIDITY AND PERCEIVED FAIRNESS OF A MEDICAL LONG CASE ASSESSMENT', MEDICAL EDUCATION, 34 46-52 (2000) [C1]
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2000 |
Wark PA, Saltos N, Simpson J, Slater S, Hensley MJ, Gibson PG, 'Induced sputum easinophils and neutrophils and bronchiectasis severity in allergic bronchopulmonary aspergillosis', European Respiratory Journal, 16 1095-1101 (2000) [C1]
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2000 |
Hensley M, Coughlan JL, Gibson P, 'Lung volume reduction surgery for diffuse emphysema.', Cochrane database of systematic reviews (Online), (2000)
BACKGROUND: Lung volume reduction surgery (LVRS) has been re-introduced for treating patients with severe diffuse emphysema. OBJECTIVES: To assemble evidence from randomised contr... [more]
BACKGROUND: Lung volume reduction surgery (LVRS) has been re-introduced for treating patients with severe diffuse emphysema. OBJECTIVES: To assemble evidence from randomised controlled trials for the effectiveness of LVRS, and identify optimal surgical techniques, those patients who benefit most and those for whom it should be avoided. SEARCH STRATEGY: Randomised controlled trials were identified using the Cochrane Airways Group COPD register using the terms: emphysema AND (emphysema surgery OR lung volume reduction surgery OR LVRS OR volume reduction surgery OR pneumectomy OR reduction pneumoplasty OR lung reduction surgery). The Cochrane Controlled Clinical Trials Register was also searched using these terms. SELECTION CRITERIA: Randomised controlled trials that studied the safety and efficacy of LVRS in patients with diffuse emphysema were included. Studies were excluded if they investigated giant or bullous emphysema. DATA COLLECTION AND ANALYSIS: Two independent reviewers assessed trials for inclusion and extracted data. MAIN RESULTS: Only one randomised trial of LVRS for diffuse emphysema was identified. This compared stapled unilateral thoracoscopic lung reduction coupled with bovine pericardium reinforcement with a unilateral neodymium:yttrium aluminium garnet laser contact reduction. A total of 72 patients were studied. Both arms included post-operative rehabilitation and appeared to be well matched at randomisation. Improvement in FEV1 & FVC at six months was significantly greater in the staple treated group (p < 0.01 & p < 0. 07 respectively), but absolute increases were small. Need for supplemental oxygen was reduced significantly more in the staple treated group; Peto Odds Ratio (OR) 4.05; 95% confidence interval (CI) 1.40, 11.71. Quality of life improved more in the staple treated group (OR 5.36; 95% CI 2.13,13.47). The rate of delayed pneumothorax in the laser treated group was significantly higher (OR 10.46; 95% CI 1.98, 55.30). REVIEWER'S CONCLUSIONS: There is no randomised controlled trial evidence concerning the efficacy of LVRS for diffuse emphysema compared to optimal conservative medical therapy. Stapling is more effective than laser resection and has a lower complication rate. LVRS should not be applied routinely until results of large trials currently underway become available.
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2000 |
Hensley M, Coughlan JL, Gibson P, 'Lung volume reduction surgery for diffuse emphysema', Praxis, 89 1393 (2000)
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2000 |
Gibson PG, Coughlan J, Wilson AJ, Hensley MJ, Abramson M, Bauman A, Walters EH, 'Limited (information only) patient education programs for adults with asthma.', Cochrane database of systematic reviews (Online), (2000)
BACKGROUND: A key component of many asthma management guidelines is the recommendation for patient education and regular medical review. A number of controlled trials have been co... [more]
BACKGROUND: A key component of many asthma management guidelines is the recommendation for patient education and regular medical review. A number of controlled trials have been conducted to measure the effectiveness of asthma education programmes. These programmes improve patient knowledge, but their impact on health outcomes is less well established. At its simplest level, education is limited to the transfer of information about asthma, its causes and its treatment. This review focused on the effects of limited asthma education. OBJECTIVES: The objective of this review was to assess the effects of limited (i.e. information only) asthma education on health outcomes in adults with asthma. SEARCH STRATEGY: We searched the Cochrane Airways Group trials register and reference lists of articles. SELECTION CRITERIA: Randomised and controlled trials of individual asthma education involving information transfer only in adults over 16 years of age. DATA COLLECTION AND ANALYSIS: Trial quality was assessed and data were extracted independently by two reviewers. Study authors were contacted for missing information. MAIN RESULTS: Eleven trials were included. They were of variable quality. Limited asthma education did not reduce hospitalisation for asthma (weighted mean difference -0.03 average hospitalisations per person per year, 95% confidence interval -0.09 to 0.03). There was no effect on doctor visits, lung function and medication use. The effects on asthma symptoms were variable. There was no reduction in days lost from normal activity, but perceived asthma symptoms did improve after limited asthma education (odds ratio 0.40, 95% confidence interval 0.18 to 0.86). In one study, limited asthma education was associated with reduced emergency department visits (weighted mean difference -2.76 average visits per person per year, 95% confidence interval -4.34 to 1.18). REVIEWER'S CONCLUSIONS: Use of limited asthma education as it has been practiced does not appear to improve health outcomes in adults with asthma. However the use of information in the emergency department may be effective, but this needs to be confirmed.
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2000 |
Gibson PG, Coughlan J, Wilson AJ, Abramson M, Bauman A, Hensley MJ, Walters EH, 'Self-management education and regular practitioner review for adults with asthma.', Cochrane database of systematic reviews (Online), (2000)
BACKGROUND: A key component of many asthma management guidelines is the recommendation for patient education and regular medical review. A number of controlled trials have been co... [more]
BACKGROUND: A key component of many asthma management guidelines is the recommendation for patient education and regular medical review. A number of controlled trials have been conducted to measure the effectiveness of asthma education programmes. These programmes improve patient knowledge, but their impact on health outcomes is less well established. This review was conducted to examine the strength of evidence supporting Step 6 of the Australian Asthma Management Plan: "Educate and Review Regularly"; to test whether health outcomes are influenced by education and self-management programmes. OBJECTIVES: The objective of this review was to assess the effects of asthma self-management programmes, when coupled with regular health practitioner review, on health outcomes in adults with asthma. SEARCH STRATEGY: We searched the Cochrane Airways Group trials register and reference lists of articles. SELECTION CRITERIA: Randomised trials of self-management education in adults over 16 years of age with asthma. DATA COLLECTION AND ANALYSIS: Trial quality was assessed and data were extracted independently by two reviewers. Study authors were contacted for confirmation. MAIN RESULTS: Twenty-five trials were included. Self-management education was compared with usual care in 22 studies. Self-management education reduced hospitalisations (odds ratio 0.57, 95% confidence interval 0.38 to 0.88); emergency room visits (odds ratio 0.71, 95% confidence interval (0.57 to 0.90); unscheduled visits to the doctor (odds ratio 0.57, 95% confidence interval 0.40 to 0.82); days off work or school (odds ratio 0.55, 95% confidence interval 0.38 to 0. 79); and nocturnal asthma (odds ratio 0.53, 95% confidence interval 0.39 to 0.72). Measures of lung function were little changed. Self-management programmes that involved a written action plan showed a greater reduction in hospitalisation than those that did not (odds ratio 0.35, 95% confidence interval 0.18 to 0.68). People who managed their asthma by self-adjustment of their medications using an individualised written plan had better lung function than those whose medications were adjusted by a doctor. REVIEWER'S CONCLUSIONS: Training in asthma self-management which involves self-monitoring by either peak expiratory flow or symptoms, coupled with regular medical review and a written action plan appears to improve health outcomes for adults with asthma. Training programmes which enable people to adjust their medication using a written action plan appear to be more effective than other forms of asthma self-management.
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1999 |
Metlay JP, Kapoor WN, Fine MJ, Hensley MJ, Arnold D, 'Clinical assessment is inaccurate for diagnosing community-acquired pneumonia', Enfermedades Infecciosas y Microbiologia, 19 101-102 (1999) |
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1999 |
Gibson PG, Coughlan J, Wilson AJ, Hensley MJ, Abramson M, Bauman A, Walters EH, 'Limited (information only) patient education programs for adults with asthma', Praxis, 88 1570 (1999)
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1999 |
Gibson PG, Coughlan J, Wilson AJ, Abramson M, Haywood P, Bauman A, et al., 'Self-management education and regular practitioner review for adults with asthma', Praxis, 88 1571-1572 (1999)
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1999 |
Wark P, Simpson J, Fakes K, Burgess H, Timmins N, Hensley M, Gibson PG, 'Airway inflammation in allergic bronchopulmonary aspergillosis', Respirology, 4 (1999)
Allergic bronchopulmonary aspergillosis (ABPA) is a serious complication of asthma. In uncomplicated asthma airway inflammation(ai) is characterised by sputum eosinophilia without... [more]
Allergic bronchopulmonary aspergillosis (ABPA) is a serious complication of asthma. In uncomplicated asthma airway inflammation(ai) is characterised by sputum eosinophilia without an increase in the total cell count (TCC). In bronchiectasis the intensity of ai increased and there is a neutrophil infiltrate. Airway inflammation in ABPA is not well defined. This study tested the hypothesis that ai in ABPA would be of increased intensity with a mixed eosinophil/neutrophil pattern. Methods: In subjects with asthma, ABPA was assessed by 5 criteria; 1. positive allergy skin test to Aspergillus Fumigatus (Af); 2. raised specific serum IgE to Af; 3. positive precipitating antibodies to Af; 4. total IgE > 10001U/ml and 5. bronchiectasis (CT scan). Subjects were classified as definite ABPA (n=13) with criteria 1, 2, 3 and either 4 or 5; or as probable ABPA (n=18) with 1 and 2 and either 3, 4 or 5 (n=13). These groups were combined for analysis. Af sensitised subjects (n=19 with positive skin testing alone), were compared to a matched group with asthma (negative to Af on skin test) (n=15) and healthy controls (n=8). Spirometry, saline challenge and sputum induction were performed, with results reported as medians and interquartile ranges. Results: Patients with ABPA had an increased TCC (4.6, 0.9-29.6) compared to: Af sensitised (3.6, 1.4-7.4), asthma (1.5, 0.8-3.2), and controls (1.35, 1.3-1.4) (p<0.05). Those with ABPA had increased sputum eosinophils (3.8, 0.3-16.3), compared to: Af sensitised (1.4, 0.1-6), asthma (1.6, 0.01-3), and controls (0.3, 0.3-0.31 ) (p=0.001). Those with ABPA had increased levels of eosinophil cationic protein(ng/ml) (5471, 311-42485) compared to: Af sensitised (1432, 338-6902), asthma (244, 78-857), and controls (110, 99-121 ) (p<0.001). Neutrophil counts were similar in all groups. Myeloperoxidase was similar in ABPA (232, 66-454) and asthma (177, 57-318) (p=0.3) but greater than in healthy controls (76, 76-89) Conclusion: Airway inflammation in ABPA is of increased intensity compared to that of chronic asthma. Unlike bronchiectasis, the cellular infiltrate is predominantly eosinophilic. The eosinophils demonstrate increased activation.
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1999 |
Hensley MJ, 'Antibiotics are ineffective for acute bronchitis', Enfermedades Infecciosas y Microbiologia, 19 43-44 (1999) |
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Nova |
1998 |
Silberberg JS, Wlodarczyk J, Fryer J, Ray CD, Hensley MJ, 'Correction for biases in a population-based study of family history and coronary heart disease - The Newcastle Family History Study I', AMERICAN JOURNAL OF EPIDEMIOLOGY, 147 1123-1132 (1998)
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1998 |
Silberberg JS, Wlodarczyk J, Fryer J, Robertson R, Hensley MJ, 'Correction for biases in a population-based study of family history and coronary heart disease - The Newcastle Family History Study II', AMERICAN JOURNAL OF EPIDEMIOLOGY, 147 1133-1139 (1998)
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1998 |
Silberberg JS, Wlodarczyk J, Fryer J, Robertson R, Hensley MJ, 'Risk associated with various definitions of family history of coronary heart disease the newcastle family history study II', American Journal of Epidemiology, 147 1133-1139 (1998)
The authors carried out a population-based case-control study to estimate the risk of an acute coronary disease event associated with various definitions of a family history of co... [more]
The authors carried out a population-based case-control study to estimate the risk of an acute coronary disease event associated with various definitions of a family history of coronary heart disease (CHD). A detailed family history questionnaire was completed by 403 cases and 236 controls in Newcastle, New South Wales, Australia from 1992 to 1994. Odds ratios of an acute coronary disease event adjusted for proband age and sex ranged from 2.7 (95% confidence interval (CI) 1.8-4.1) for the simplest definition (one or more first-degree relatives with CHD at any age) to 5.4 (95% CI 1.7-16.8) for the most stringent definition (two or more first-degree relatives with CHD before age 55 years). In a series of nested models, the authors examined the improvement in model fit as each component of the detailed family history was added. Additional information was provided by accounting for 'don't know' responses, the number of affected relatives, the age of the affected relative, and whether the first-degree relative was a sibling rather than a parent. The results were similar when the data were analyzed as a cohort design with proband disease status as the exposure variable. The authors suggest that, to facilitate preventive efforts in a population, more detailed family history definitions should be used to better target high risk subjects.
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Nova |
1998 |
Hensley MJ, 'Use of inhaled corticosteroids was associated with the development of cataracts', Evidence-Based Medicine, 3 24 (1998)
To determine the effect of inhaled corticosteroid use on the development of cataracts in older adults. Design Community-based study with data collected during 1992 and 1993. Setti... [more]
To determine the effect of inhaled corticosteroid use on the development of cataracts in older adults. Design Community-based study with data collected during 1992 and 1993. Setting District general hospital west of Sydney, Australia. Patients 4433 patients who were born before 1943 were identified by door-to-door census and invited to attend the study clinic for an eye examination. 3654 attended, of whom 3313 (mean age 66 y, 57% women) provided information on corticosteroid use. Assessment of risk factors Patients completed questionnaires specifying inhaled corticosteroid use (currently, in the past, or never). Investigators categorized beclomediasone use for usual number of puffs/wk and cal-culated the estimated lifetime dose. Other risk factors assessed were history of smoking, diabetes, and hypertension; socioeconomic status; and sun-related skin damage. Main outcome measures Nuclear cataracts were identified, and their severity was graded by comparing photographs of the patients' eyes with 4 standard photographs; cortical and posterior subcapsular cataracts were graded by estimating the percentage of the lens covered by opacity. Relative-prevalence (RP) ratios were calculated for each type of cataract. Main results The rates of posterior subcapsular, cortical, and nuclear cataracts were 6%, 24%, and 19%, respectively. 11% of participants had used inhaled corticosteroids. The use of inhaled corticosteroids at any time was associated with increased prevalence of nuclear cataracts (RP 1.5,95% CI 1.2 to 1.9) and posterior subcapsular cataracts (RP 1.9, CI 1.3 to 2.8). Higher cumulative lifetime doses of beclomethasone were associated with increased prevalence of posterior subcapsular cataracts. For a lifetime dose of beclomethasone A 2 000 mg among current users, the RP for posterior subcap-sular cataracts was 5.5 (CI 2.3 to 13.0, P for trend < 0.001). The prevalence of nuclear cataracts was also greater at that dose of beclomethasone (RP 4.0, CI 1.8 to 9.3). An increased prevalence of cortical cataracts was seen only with current use of inhaled corticpsteroids (RP 1.4, CI 1.1 to 1.7). Adjustment for risk factors, including systemic corticosteroid use, did not affect the strength of the association between inhaled corticosteroid use and the presence of posterior subcapsular cataracts (odds ratio for lifetime dose of beclomethasone a 2000 mg 10.0, CI 3.3 to 33.2, P for trend < 0.001). Conclusion Use of inhaled corticosteroids was associated with increased risk for the development of nuclear and posterior subcapsular cataracts.
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Nova |
1998 |
Silberberg JS, Wlodarczyk J, Fryer J, Ray CD, Hensley MJ, 'Correction for Biases in a Population-based Study of Family History and Coronary Heart Disease.', American Journal of Epidemiology, 147 1123-1132 (1998) [C1] |
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1998 |
Silberberg JS, Wlodarczyk J, Fryer J, Robertson R, Hensley MJ, 'Risk associated with the various definitions of family history of coronary heart disease', American Journal of Epidemiology, 147(12) 1133-1139 (1998) [C1] |
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1998 |
Gibson PG, Wlodarczyk J, Hensley MJ, Henry RL, Cripps AW, Clancy RL, Gleeson M, 'Epidemiological association of airway inflammation with asthma symptoms and airway hyperresponsiveness in childhood', American Journal of Respiratory and Critical Care Medicine., 158 36-41 (1998) [C1]
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1998 |
Pearce N, Hensley MJ, 'Epidemiologic studies of beta-agonists and asthma deaths', Epidemiologic Reviews, 20(2) 173-186 (1998) [C1]
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1998 |
Nair BR, Coughlan JL, Hensley MJ, 'Impediments to bed-side teaching.', Medical Education, 32 159-162 (1998) [C1]
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1998 |
Lewis PR, Hensley MJ, Wlodarczyk J, Toneguzzi R, Westley-Wise VJ, Dunn T, Calvert D, 'Outdoor air pollution and children's respiratory symptoms in the steel cities of New South Wales', Medical Journal of Australia, 169 459-463 (1998) [C1]
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1998 |
Hensley MJ, Gibson PG, 'Promoting evidence-based alternative medicine', Medical Journal of Australia, 169 573-574 (1998) [C1]
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1998 |
Ferguson JK, Hensley MJ, 'Should third-generation cephalosporins be the empirical treatment of choice for severe community-acquired pneumonia in adults?', The Medical Journal of Australia, 169 230 (1998) [C3] |
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1997 |
Carney IK, Gibson PG, MurreeAllen K, Saltos N, Olson LG, Hensley MJ, 'A systematic evaluation of mechanisms in chronic cough', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 156 211-216 (1997)
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1997 |
Aldrich R, Toneguzzi R, Wlodarczyk J, Hensley M, Nichols B, Gruszynski C, Vimpani G, 'Opportunistic blood lead testing in a paediatric inpatient population', AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH, 21 163-167 (1997)
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1997 |
Nair BR, Coughlan JL, Hensley MJ, 'Student and patient perspectives on bedside teaching', MEDICAL EDUCATION, 31 341-346 (1997)
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1997 |
Slatyer MA, Hensley MJ, 'A randomized controlled trial of piroxicam in the management of acute ankle sprain in Australian regular Army recruits - The Kapooka ankle sprain study', AMERICAN JOURNAL OF SPORTS MEDICINE, 25 544-553 (1997)
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1997 |
Hancock L, SansonFisher RW, Redman S, Burton R, Burton L, Butler J, et al., 'Community action for health promotion: A review of methods and outcomes 1990-1995', AMERICAN JOURNAL OF PREVENTIVE MEDICINE, 13 229-239 (1997)
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1996 |
Olson LG, King MT, Saunders NA, Hensley MJ, 'Emerging issues in sleep-disordered breathing', MEDICAL JOURNAL OF AUSTRALIA, 165 107-110 (1996)
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1996 |
Gleeson M, Cripps AW, Hensley MJ, Wlodarczyk JH, Henry RL, Clancy RL, 'A clinical evaluation in children of the Pharmacia ImmunoCAP system for inhalant allergens', CLINICAL AND EXPERIMENTAL ALLERGY, 26 697-702 (1996)
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Nova |
1996 |
SansonFisher R, Redman S, Hancock L, Halpin S, Clarke P, Schofield M, et al., 'Developing methodologies for evaluating community-wide health promotion', HEALTH PROMOTION INTERNATIONAL, 11 227-236 (1996)
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1996 |
Hancock L, SansonFisher R, Redman S, Burton R, Burton L, Butler J, et al., 'Community action for cancer prevention: Overview of the cancer action in rural towns (CART) project, Australia', HEALTH PROMOTION INTERNATIONAL, 11 277-290 (1996)
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1996 |
Gibson PG, Stuart JE, Wlodarczyk J, Olson LG, Hensley MJ, 'Nasal inflammation and chronic ear disease in Australian Aboriginal children', JOURNAL OF PAEDIATRICS AND CHILD HEALTH, 32 143-147 (1996)
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1996 |
Gleeson M, Clancy RL, Hensley MJ, Cripps AW, Henry RL, Wlodarczyk JH, Gibson PG, 'Development of bronchial hyperreactivity following transient absence of salivary IgA', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 153 1785-1789 (1996)
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1995 |
ROLFE IE, ANDREN JM, PEARSON S, HENSLEY MJ, GORDON JJ, 'CLINICAL COMPETENCE OF INTERNS', MEDICAL EDUCATION, 29 225-230 (1995)
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1995 |
Rolfe IE, Andren JM, Pearson S, Hensley MJ, Gordon JJ, 'Clinical competence of interns. Programme Evaluation Committee (PEC).', Medical education, 29 225-230 (1995)
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1995 |
OLSON LG, KING MT, HENSLEY MJ, SAUNDERS NA, 'A COMMUNITY STUDY OF SNORING AND SLEEP-DISORDERED BREATHING - SYMPTOMS', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 152 707-710 (1995)
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Nova |
1995 |
OLSON LG, KING MT, HENSLEY MJ, SAUNDERS NA, 'A COMMUNITY STUDY OF SNORING AND SLEEP-DISORDERED BREATHING - PREVALENCE', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 152 711-716 (1995)
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1995 |
OLSON LG, KING MT, HENSLEY MJ, SAUNDERS NA, 'A COMMUNITY STUDY OF SNORING AND SLEEP-DISORDERD BREATHING - HEALTH OUTCOMES', AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 152 717-720 (1995)
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Nova |
1995 |
ROWLEY MJ, HENSLEY MJ, BRINSMEAD MW, WLODARCZYK JH, 'CONTINUITY OF CARE BY A MIDWIFE TEAM VERSUS ROUTINE CARE DURING PREGNANCY AND BIRTH - A RANDOMIZED TRIAL', MEDICAL JOURNAL OF AUSTRALIA, 163 289-293 (1995)
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1995 |
GIBSON PG, WLODARCZYK J, HENSLEY MJ, MURREEALLEN K, OLSON LG, SALTOS N, 'USING QUALITY-CONTROL ANALYSIS OF PEAK EXPIRATORY FLOW RECORDINGS TO GUIDE THERAPY FOR ASTHMA', ANNALS OF INTERNAL MEDICINE, 123 488-+ (1995)
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1995 |
Nair BR, Hensley MJ, Pickles RW, Fowler J, 'Morning report: Essential part of tra patient care in internal medicine', AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 25 740-740 (1995)
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1995 |
GLEESON M, CRIPPS AW, CLANCY RL, HENSLEY MJ, HENRY RJ, WLODARCZYK JH, 'The significance of transient mucosal IgA deficiency on the development of asthma and atopy in children', ADVANCES IN MUCOSAL IMMUNOLOGY, PTS A AND B, 371 861-864 (1995)
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Nova |
1994 |
SILBERBERG J, WLODARCZYK J, HENSLEY M, RAY C, ALEXANDER H, BASTA M, HUGHES J, 'ACCURACY OF REPORTED FAMILY HISTORY OF HEART-DISEASE - THE IMPACT OF DONT KNOW RESPONSES', AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 24 386-389 (1994)
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1994 |
Gravenstein S, Duthie EH, Miller BA, Brown CS, Hensley M, Circo R, et al., 'Efficacy of an Influenza Hemagglutinin-Diphtheria Toxoid Conjugate Vaccine in Elderly Nursing Home Subjects During an Influenza Outbreak', Journal of the American Geriatrics Society, 42 245-251 (1994)
To compare the efficacy of an influenza hemagglutinin-diphtheria toxoid conjugate vaccine with the commercially available influenza hemagglutinin-subunit vaccine in preventing inf... [more]
To compare the efficacy of an influenza hemagglutinin-diphtheria toxoid conjugate vaccine with the commercially available influenza hemagglutinin-subunit vaccine in preventing influenza in older adults living in a nursing home. A prospective, randomized, double-blind vaccine trial with 5 months of follow-up after vaccination. Fourteen Wisconsin nursing homes. Nursing home residents at least 65 years old who were able to give informed consent and were free of malignancy and not receiving immunosuppressive therapy. Participants received, by intramuscular injection, 0.5 mL of a trivalent influenza vaccine containing 15 µg each of A/Leningrad/360/86 (H3N2), A/Taiwan/1/86 (H1N1), and B/Ann Arbor/1/86 (HA) or 0.5 mL of an influenza vaccine containing the same antigens conjugated to diphtheria toxoid (HA-D). Blood was obtained pre- and 1 month post-vaccination to assess for any vaccine-induced antibody titer change. Clinical surveillance for respiratory illness was performed twice weekly for 5 months. A record was kept of all signs and symptoms of new respiratory illness, and a viral culture and acute and convalescent sera were obtained. 204 participants received HA and 204 received HAD. Both groups had similar baseline antibody levels to all influenza antigens. HA-D recipients seroconverted more frequently based on serum neutralizing activity (P < 0.05), had a greater increase in geometric mean titer (GMT), and sustained the increase in antibody titer longer than HA recipients. Vaccine hemagglutinin recall was greater in a subset of HA-D recipients as measured by lymphocyte proliferative assays (P < 0.05). During an outbreak of influenza A (H3N2 A/Shanghai/11/87-like and A/Victoria/7/87-like), fewer HA-D (29/195) than HA (43/204) recipients had laboratory-confirmed infection (P = 0.053), and, of these, fewer HA-D-treated subjects had lower respiratory tract involvement (5/29 HA-D and 17/43 HA) (P = 0.022). HA-D was more immunogenic in institutionalized elderly recipients and produced greater protection from influenza infection. Superior protection may be due to HAD's ability to stimulate and recruit antigen-presenting cells, thus enabling the recipient to achieve and maintain functional antibody titers. © 1994 The American Geriatrics Society
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1994 |
Gleeson M, Clancy RL, Cripps AW, Henry RL, Hensley MJ, Wlodarczyk JH, 'Acquired IgA deficiency', Pediatric Allergy and Immunology, 5 157-161 (1994)
During a prospective study of the ontogeny of the mucosal immune system using saliva, one subject acquired a selective IgA deficiency at 3 years 6 months of age. Prior to this tim... [more]
During a prospective study of the ontogeny of the mucosal immune system using saliva, one subject acquired a selective IgA deficiency at 3 years 6 months of age. Prior to this time the infant had normal ontogeny patterns for salivary immunoglobulins and the salivary IgA was confirmed to be dimeric IgA containing secretory component. Two respiratory tract infections at 3 years 4 months and 3 years 5 months were reported prior to the collection of a saliva sample which was deficient in IgA. All subsequent saliva collections remained IgA deficient. Serum and saliva collected at 11 years of age confirmed persistent IgA deficiency. There was a family history of organ-specific autoimmune disease. The prospectively collected data indicate in this subject that the IgA deficiency was not congenital, but was acquired closely associated with two episodes of respiratory tract infections, against a genetic background of disturbed immune regulation. Copyright © 1994, Wiley Blackwell. All rights reserved
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Nova |
1994 |
PERKINS JJ, SANSONFISHER RW, BLUNDEN S, LUNNAY D, REDMAN S, HENSLEY MJ, 'THE PREVALENCE OF DRUG-USE IN URBAN ABORIGINAL COMMUNITIES', ADDICTION, 89 1319-1331 (1994)
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1994 |
WILKINSON IA, HALLIDAY JA, HENRY RL, HANKIN RG, HENSLEY MJ, 'HEADACHE AND ASTHMA', JOURNAL OF PAEDIATRICS AND CHILD HEALTH, 30 253-256 (1994)
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1993 |
GYULAY S, OLSON LG, HENSLEY MJ, KING MT, ALLEN M, SAUNDERS NA, 'A COMPARISON OF CLINICAL-ASSESSMENT AND HOME OXIMETRY IN THE DIAGNOSIS OF OBSTRUCTIVE SLEEP-APNEA', AMERICAN REVIEW OF RESPIRATORY DISEASE, 147 50-53 (1993)
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1993 |
HENSLEY MJ, KING M, OLSON LG, SAUNDERS NA, 'SLEEP-DISORDERED BREATHING (SDB) AND CARDIOVASCULAR-DISEASE', AMERICAN REVIEW OF RESPIRATORY DISEASE, 147 A1018-A1018 (1993) |
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1993 |
ALDRICH R, WLODARCZYK J, HENSLEY MJ, 'CHILDRENS BLOOD LEAD LEVELS AND ENVIRONMENTAL LEAD CONTAMINATION', MEDICAL JOURNAL OF AUSTRALIA, 158 506-506 (1993)
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1993 |
ALDRICH R, HENSLEY MJ, 'VACCINATION AGAINST INFLUENZA INFECTION', MEDICAL JOURNAL OF AUSTRALIA, 158 634-637 (1993)
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1993 |
GIBSON PG, TALBOT PI, HANCOCK J, HENSLEY MJ, 'A PROSPECTIVE AUDIT OF ASTHMA MANAGEMENT FOLLOWING EMERGENCY ASTHMA-TREATMENT AT A TEACHING HOSPITAL', MEDICAL JOURNAL OF AUSTRALIA, 158 775-778 (1993)
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1993 |
ALDRICH R, HENSLEY MJ, 'VACCINATION AGAINST INFLUENZA INFECTION - REPLY', MEDICAL JOURNAL OF AUSTRALIA, 159 707-707 (1993)
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1993 |
Aldrich R, Hensley MJ, 'Vaccination against influenza infection. Thoracic Society of Australia and New Zealand.', The Medical journal of Australia, 158 634-637 (1993)
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1993 |
HALLIDAY JA, HENRY RL, HANKIN RG, HENSLEY MJ, 'INCREASED WHEEZE BUT NOT BRONCHIAL HYPERREACTIVITY NEAR POWER-STATIONS', JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, 47 282-286 (1993)
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1993 |
Olson LG, King MT, Hensley MJ, Saunders NA, 'The Newcastle study of snoring and sleep disordered breathing.', Sleep, 16 S8-S9 (1993)
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1993 |
TANNOCK GA, REID ALA, GILLETT SM, HERD R, GILLETT RS, HENSLEY MJ, et al., 'A STUDY OF RESPIRATORY-INFECTIONS IN A HEALTHY ADULT-POPULATION DURING THE 1987 AUSTRALIAN WINTER', FAMILY PRACTICE, 10 378-386 (1993)
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1992 |
Spitzer WO, Ernst P, Suissa S, Boivin JF, Horwitz RI, Habbick B, et al., 'Fenoterol and death from asthma [3]', Medical Journal of Australia, 157 567-568 (1992)
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1992 |
TAYLOR DC, CRIPPS AW, CLANCY RL, MURREEALLEN K, HENSLEY MJ, SAUNDERS NA, SUTHERLAND DC, 'BIOTYPES OF HAEMOPHILUS-PARAINFLUENZAE FROM THE RESPIRATORY SECRETIONS IN CHRONIC-BRONCHITIS', JOURNAL OF MEDICAL MICROBIOLOGY, 36 279-282 (1992)
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1992 |
BAUMAN A, MITCHELL CA, HENRY RL, ROBERTSON CF, ABRAMSON MJ, COMINO EJ, et al., 'ASTHMA MORBIDITY IN AUSTRALIA - AN EPIDEMIOLOGIC-STUDY', MEDICAL JOURNAL OF AUSTRALIA, 156 827-831 (1992)
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1992 |
HENSLEY MJ, 'FENOTEROL AND DEATH FROM ASTHMA', MEDICAL JOURNAL OF AUSTRALIA, 156 882-882 (1992)
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1992 |
HENSLEY MJ, 'FENOTEROL AND DEATH FROM ASTHMA - REPLY', MEDICAL JOURNAL OF AUSTRALIA, 157 568-568 (1992)
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1992 |
Stuart J, Hensley, Olson L, 'A Randomised Double Blind Controlled Trial of Nasal Beclomethasone in Ear Disease in Aboriginal Children', Journal of Paediatrics and Child Health, 28 112-112 (1992)
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1991 |
CLANCY RL, RUHNO J, SCICCHITANO R, CRIPPS AW, HENSLEY MJ, SAUNDERS NA, et al., 'WHEAT DUST-ASSOCIATED RESPIRATORY-DISEASE IN A FARMING COMMUNITY', AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 21 222-226 (1991)
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1991 |
LORD S, SAWYER B, OCONNELL D, KING M, POND D, EYLAND A, et al., 'NIGHT-TO-NIGHT VARIABILITY OF DISTURBED BREATHING DURING SLEEP IN AN ELDERLY COMMUNITY SAMPLE', SLEEP, 14 252-258 (1991)
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1991 |
Abramson MJ, Hensley MJ, Saunders NA, Wlodarczyk JH, 'Evaluation of a new asthma questionnaire', Journal of Asthma, 28 129-139 (1991)
The new International Union Against Tuberculosis (IUAT) bronchial symptoms questionnaire was completed by 827 subjects participating in a prospective study of respiratory symptoms... [more]
The new International Union Against Tuberculosis (IUAT) bronchial symptoms questionnaire was completed by 827 subjects participating in a prospective study of respiratory symptoms and lung function in aluminum smelter workers. A modified Medical Research Council (MRC) questionnaire was also administered. Bronchial reactivity (BR) was measured in 809 subjects by metha-choline challenge using a rapid method. Factor analysis demonstrated sensible clustering of responses to items unqiue to the new questionnaire such as nocturnal, spontaneous, and postexertional dyspnea, dust-induced dyspnea and tightness, and breathing difficulty. Responses to IUAT questions concerning past asthma, wheeze, chest tightness, morning cough and sputum, and asthma medication agreed well with corresponding items from the MRC questionnaire. Questions concerning asthma, medication, dust-induced, nocturnal, and spontaneous dyspnea, chest tightness, wheeze, nocturnal cough, postex-ertional dyspnea and breathing difficulty also had high validity against the criterion of concurrently measured bronchial reactivity. It is concluded that the IUAT questionnaire is a valid asthma questionnaire. © 1991 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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1991 |
GLEESON M, DOBSON AJ, FIRMAN DW, CRIPPS AW, CLANCY RL, WLODARCZYK JH, HENSLEY MJ, 'THE VARIABILITY OF IMMUNOGLOBULINS AND ALBUMIN IN SALIVARY SECRETIONS OF CHILDREN', SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 33 533-541 (1991)
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1991 |
TANNOCK GA, BRYCE DA, BARNETT GR, HAMPSON AW, HENSLEY MJ, SAUNDERS NA, 'MEASUREMENT OF IGM RESPONSES TO A SUBUNIT INFLUENZA-A VACCINE BY SUCROSE-GRADIENT CENTRIFUGATION AND MEMBRANE-FILTRATION ENZYME IMMUNOASSAYS', BIOLOGICALS, 19 17-21 (1991)
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1991 |
HENRY RL, ABRAMSON R, ADLER JA, WLODARCYZK J, HENSLEY MJ, 'ASTHMA IN THE VICINITY OF POWER-STATIONS .1. A PREVALENCE STUDY', PEDIATRIC PULMONOLOGY, 11 127-133 (1991)
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1991 |
HENRY RL, BRIDGMAN HA, WLODARCZYK J, ABRAMSON R, ADLER JA, HENSLEY MJ, 'ASTHMA IN THE VICINITY OF POWER-STATIONS .2. OUTDOOR AIR-QUALITY AND SYMPTOMS', PEDIATRIC PULMONOLOGY, 11 134-140 (1991)
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1990 |
Abramson MJ, Saunders NA, Hensley MJ, 'Analysis of bronchial reactivity in epidemiological studies', Thorax, 45 924-929 (1990)
The measurement of bronchial reactivity in epidemiological studies has the advantage of quantifying an objective physiological feature of asthma. Bronchial reactivity was develope... [more]
The measurement of bronchial reactivity in epidemiological studies has the advantage of quantifying an objective physiological feature of asthma. Bronchial reactivity was developed in a clinical setting and has been conventionally expressed as the dose of agonist producing a 20% fall in FEV1 (PD20). As PD20 can be estimated for less than 20% of subjects in general community surveys with the doses of agonist that are usually given, data from most subjects must be censored. Thus PD20 alone is a poor index of bronchial reactivity for epidemiological studies. Data from 809 aluminium smelter workers were used to evaluate alternative methods of analysing bronchial reactivity. Dose-response relationships were analysed by four methods: (1) PD20 by the conventional method of interpolating the dose on a logarithmic scale between the last two measurements of FEV1; (2) PD20 (with allowance for extrapolation), estimated by fitting an exponential curve to the dose-response data; (3) the linear regression slope between dose and FEV1 when significant; (4) the dose-response slope obtained in all subjects as the % change in FEV1 from baseline in response to total dose. When each of these measures was related to symptoms, diagnosis, and treatment of asthma, all differentiated between 'asthmatic' and 'non-asthmatic' subjects. The dose-response slope (method 4) had the advantages of simplicity and no censored data, and was shown to be clinically relevant. It is suggested that the dose-response slope should be used for the analysis of bronchial reactivity in epidemiological studies.
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Nova |
1990 |
MCKEON JL, SAUNDERS NA, MURREEALLEN K, OLSON LG, GYULAY S, DICKESON J, et al., 'URINARY URIC-ACID - CREATININE RATIO, SERUM ERYTHROPOIETIN, AND BLOOD 2,3-DIPHOSPHOGLYCERATE IN PATIENTS WITH OBSTRUCTIVE SLEEP-APNEA', AMERICAN REVIEW OF RESPIRATORY DISEASE, 142 8-13 (1990)
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1990 |
CROCKER BD, OLSON LG, SAUNDERS NA, HENSLEY MJ, MCKEON JL, ALLEN KM, GYULAY SG, 'ESTIMATION OF THE PROBABILITY OF DISTURBED BREATHING DURING SLEEP BEFORE A SLEEP STUDY', AMERICAN REVIEW OF RESPIRATORY DISEASE, 142 14-18 (1990)
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1990 |
BUTT HL, CLANCY RL, CRIPPS AW, MURREEALLEN K, SAUNDERS NA, SUTHERLAND DC, HENSLEY MJ, 'BACTERIAL-COLONIZATION OF THE RESPIRATORY-TRACT IN CHRONIC-BRONCHITIS', AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 20 35-38 (1990)
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1990 |
TAYLOR DC, CRIPPS AW, CLANCY RL, MURREEALLEN K, HENSLEY MJ, SAUNDERS NA, SUTHERLAND DC, 'EVALUATION OF A SELECTIVE MEDIUM FOR THE ISOLATION AND DIFFERENTIATION OF HAEMOPHILUS-INFLUENZAE AND HAEMOPHILUS-PARAINFLUENZAE FROM THE RESPIRATORY-TRACT OF CHRONIC BRONCHITICS', PATHOLOGY, 22 162-164 (1990)
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1989 |
Saunders NA, Vandeleur T, Deves J, Salmon A, Gyulay S, Crocker B, Hensley M, 'Uvulopalatopharyngoplasty as a treatment for snoring', Medical Journal of Australia, 150 177-182 (1989)
Uvulopalatopharyngoplasty was performed in 18 consecutive patients (15 men and three women; mean ± standard deviation [SD] age, 46.3 ± 7.5 years) who presented for the treatment o... [more]
Uvulopalatopharyngoplasty was performed in 18 consecutive patients (15 men and three women; mean ± standard deviation [SD] age, 46.3 ± 7.5 years) who presented for the treatment of heavy habitual snoring. No attempt was made to select patients who were ideal anatomically for palatal modification. The loudness of snoring was measured during sleep by integrating the output of a calibrated microphone. An assessment before operation showed that nine patients had obstructive sleep apnoea; four patients had an apnoea index of greater than or equal to 25 apnoeas per hour. The patients were overweight and consumed, on average, 39 g of alcohol per day, but these variables did not change after the operation. The postoperative assessment was performed 138 ± 44 days after uvulopalatopharyngoplasty. Fourteen patients showed a reduction in the loudness of their snoring, although snoring was abolished in one patient only (average snoring loudness in arbitrary units/min of sleep, 2.8 ± 2.1 before operation compared with 1.4 ± 1.5 units/min of sleep after the operation; P < 0.05. The loudest snore in arbitrary units measured 7.1 ± 3.3 units compared with 4.8 ± 3.3 units, respectively; P < 0.05). The percentage of the sleep time that was spent at an arterial oxygen saturation of less than 90% was reduced after uvulopalatopharyngoplasty (28% ± 32% of total sleep time compared with 17% ± 24% of total sleep time, respectively; P < 0.05). There was no change in the apnoea index. The diastolic blood pressure was lower at the postoperative assessment (94 ± 11 mmHg compared with 87 ± 8 mmHg; P < 0.05); six of 10 subjects whose diastolic blood pressure were greater than or equal to 95 mmHg before the operation had a diastolic blood pressure of less than 95 mmHg after uvulopalatopharyngoplasty (P < 0.02). Computed tomographic scans showed an increase in the upper airway cross-sectional area at 3 cm and 4 cm above the hyoid bone after uvulopalatopharyngoplasty (P < 0.05). We conclude that uvulopalatopharyngoplasty is an effective treatment for habitual, heavy snoring in many patients, but it is not the treatment of choice for patients with clinically-significant obstructive sleep apnoea.
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1989 |
ABRAMSON MJ, WLODARCZYK JH, SAUNDERS NA, HENSLEY MJ, 'DOES ALUMINUM SMELTING CAUSE LUNG-DISEASE', AMERICAN REVIEW OF RESPIRATORY DISEASE, 139 1042-1057 (1989)
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1989 |
ABRAMSON MJ, HENSLEY MJ, 'CHANGES IN BRONCHIAL REACTIVITY AND RESPIRATORY SYMPTOMS', AMERICAN REVIEW OF RESPIRATORY DISEASE, 139 1302-1302 (1989)
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1989 |
Abramson MJ, Wlodarczyk JH, Saunders NA, Hensley MJ, 'Does aluminum smelting cause lung disease?', American Review of Respiratory Disease, 139 1042-1057 (1989)
The evidence concerning a relationship between work in the aluminum industry and lung disease has been reviewed using epidemiologic criteria. Adequate data on environmental exposu... [more]
The evidence concerning a relationship between work in the aluminum industry and lung disease has been reviewed using epidemiologic criteria. Adequate data on environmental exposure are rarely presented. Case series on aluminum potroom workers over the past 50 years have identified an asthmalike syndrome that appears to be due to an irritant rather than an allergic mechanism. These studies have been supported by evidence of within shift variability of measures of lung function. However, to date, there is inadequate evidence to resolve the question of whether potroom exposure initiates asthma or merely precipitates asthmalike symptoms in a predisposed individual. Cross-sectional studies have demonstrated evidence of reduced lung function, consistent with chronic airflow limitation, in exposed aluminum smelter workers compared to unexposed control subjects. Cigarette smoking, the major potential confounding variable, has been measured and accounted for in multivariate analyses. To date, evidence is lacking from longitudinal studies about the development of disabling chronic obstructive lung disease. Exposure to coal tar pitch volatiles in the production and consumption of anodes has biologic plausibility for an association of lung cancer with work in an aluminum smelter. Although retrospective mortality studies have failed to account for the probable high prevalence of smoking in blue collar workers, the relative risk of lung cancer is very low if present at all. Pulmonary fibrosis has not been shown to be a significant problem in aluminum smelter workers. Future research in the aluminum industry needs to concentrate on longitudinal studies, preferably with an inception cohort for the investigation of potroom asthma.
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1989 |
TANNOCK GA, PAUL JA, HERD R, BARRY RD, REID ALA, HENSLEY MJ, et al., 'IMPROVED COLORIMETRIC ASSAY FOR DETECTING INFLUENZA-B VIRUS NEUTRALIZING ANTIBODY-RESPONSES TO VACCINATION AND INFECTION', JOURNAL OF CLINICAL MICROBIOLOGY, 27 524-528 (1989)
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1989 |
LORD S, SAWYER B, POND D, OCONNELL D, EYLAND A, MANT A, et al., 'INTERRATER RELIABILITY OF COMPUTER-ASSISTED SCORING OF BREATHING DURING SLEEP', SLEEP, 12 550-558 (1989)
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1989 |
FORD FM, HUNTER M, HENSLEY MJ, GILLIES A, CARNEY S, SMITH AJ, et al., 'HYPERTENSION AND ASTHMA - PSYCHOLOGICAL-ASPECTS', SOCIAL SCIENCE & MEDICINE, 29 79-84 (1989)
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1988 |
SAUNDERS NA, SAWYER BJ, LORD S, POND D, MANT A, EYLAND A, et al., 'RELATION BETWEEN SLEEP COMPLAINTS AND BREATHING DISTURBANCE IN THE ELDERLY', AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 18 540-540 (1988)
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1988 |
SAUNDERS NA, VANDELEUR T, DEVES J, GYULAY S, CROCKER B, HENSLEY MJ, 'UVULOPALATOPHARYNGOPLASTY (UPPP) AS TREATMENT FOR SNORING', AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 18 540-540 (1988) |
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1988 |
EVANS DB, HENSLEY MJ, OCONNOR SJ, 'INFLUENZA VACCINATION IN AUSTRALIA - A REVIEW OF THE ECONOMIC EVIDENCE FOR POLICY RECOMMENDATIONS', MEDICAL JOURNAL OF AUSTRALIA, 149 540-543 (1988)
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1988 |
BUTT HL, TAYLOR DC, CRIPPS AW, CLANCY RL, MURREEALLEN K, HENSLEY MJ, et al., 'BIOTYPING RESPIRATORY HEMOPHILUS SPECIES WITH THE MICROBACT SYSTEM', PATHOLOGY, 20 253-255 (1988)
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1988 |
PROWSE K, ALLEN MB, 'SLEEP-APNEA', BRITISH JOURNAL OF DISEASES OF THE CHEST, 82 329-340 (1988)
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1988 |
HENSLEY MJ, SCICCHITANO R, SAUNDERS NA, CRIPPS AW, RUHNO J, SUTHERLAND D, CLANCY RL, 'SEASONAL-VARIATION IN NON-SPECIFIC BRONCHIAL REACTIVITY - A STUDY OF WHEAT WORKERS WITH A HISTORY OF WHEAT ASSOCIATED ASTHMA', THORAX, 43 103-107 (1988)
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1988 |
WITHEY CH, PRICE CE, SWAN AV, PAPACOSTA AO, HENSLEY MJ, 'REPEATABILITY OF A QUESTIONNAIRE TO ASSESS RESPIRATORY SYMPTOMS IN SMOKERS', JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, 42 54-59 (1988)
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1988 |
TANNOCK GA, GILLETT SM, GILLETT RS, BARRY RD, HENSLEY MJ, HERD R, et al., 'A STUDY OF INTRANASALLY ADMINISTERED INTERFERON A (RIFN-ALPHA-2A) FOR THE SEASONAL PROPHYLAXIS OF NATURAL VIRAL-INFECTIONS OF THE UPPER RESPIRATORY-TRACT IN HEALTHY-VOLUNTEERS', EPIDEMIOLOGY AND INFECTION, 101 611-621 (1988)
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1987 |
HOWARTH DM, CHASTON TM, LICKISS K, WEEKES JR, ODOHERTY C, FOSTER RE, et al., 'AGE-RELATED RESPONSES TO INFLUENCA VACCINATION IN THE NEWCASTLE REGION DURING 1983 AND 1984', MEDICAL JOURNAL OF AUSTRALIA, 146 514-517 (1987)
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1987 |
POUNGVARIN N, BHOOPAT W, VIRIYAVEJAKUL A, RODPRASERT P, BURANASIRI P, SUKONDHABHANT S, et al., 'EFFECTS OF DEXAMETHASONE IN PRIMARY SUPRATENTORIAL INTRACEREBRAL HEMORRHAGE', NEW ENGLAND JOURNAL OF MEDICINE, 316 1229-1233 (1987)
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1987 |
Cripps AW, Clancy RL, Gleeson M, Hensley MJ, Dobson AJ, Firman DW, et al., 'Mucosal immunocompetence in man--the first five years.', Advances in experimental medicine and biology, 216 B 1369-1376 (1987)
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Nova |
1987 |
GLEESON M, CRIPPS AW, CLANCY RL, WLODARCZYK JH, HENSLEY MJ, 'IGD IN INFANT SALIVA', SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 26 55-57 (1987)
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1987 |
GLEESON M, CRIPPS AW, CLANCY RL, WLODARCZYK JH, DOBSON AJ, HENSLEY MJ, 'THE DEVELOPMENT OF IGA-SPECIFIC ANTIBODIES TO ESCHERICHIA-COLI O-ANTIGEN IN CHILDREN', SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 26 639-643 (1987)
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1987 |
EVANS DB, HENSLEY MJ, OCONNOR SJ, 'INFLUENZA VACCINATION IN AUSTRALIA - THE EVIDENCE FOR POLICY RECOMMENDATIONS', COMMUNITY HEALTH STUDIES, 11 218-218 (1987) |
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1986 |
Hensley MJ, 'Stones, Lithotripters, Trials, and Arguments', British Medical Journal (Clinical research ed.), 292 1076 (1986)
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1986 |
OLSON LG, HENSLEY MJ, SAUNDERS NA, 'THE EFFECTS OF COMBINED MORPHINE AND PROCHLORPERAZINE ON VENTILATORY CONTROL IN HUMANS', AMERICAN REVIEW OF RESPIRATORY DISEASE, 133 558-561 (1986)
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1986 |
OSTAPOWICZ G, SAUNDERS NA, HENSLEY MJ, 'BRONCHIAL REACTIVITY IN SMOKERS', AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 16 626-626 (1986) |
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1986 |
GLEESON M, CRIPPS AW, CLANCY RL, HENSLEY MJ, DOBSON AJ, FIRMAN DW, 'BREAST-FEEDING CONDITIONS A DIFFERENTIAL DEVELOPMENTAL PATTERN OF MUCOSAL IMMUNITY', CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 66 216-222 (1986)
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1986 |
CORMICK W, OLSON LG, HENSLEY MJ, SAUNDERS NA, 'NOCTURNAL HYPOXEMIA AND QUALITY OF SLEEP IN PATIENTS WITH CHRONIC OBSTRUCTIVE LUNG-DISEASE', THORAX, 41 846-854 (1986)
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1986 |
HENSLEY MJ, 'STONES, LITHOTRIPTERS, TRIALS, AND ARGUMENTS', BRITISH MEDICAL JOURNAL, 292 1076-1076 (1986)
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1986 |
Nickolls PM, Hensley MJ, 'Technique for assessing the response of the respiratory controller to hypoxia and hypercapnia', Journal of Biomedical Engineering, 8 305-312 (1986)
A technique, suitable for clinical practice, has been developed to measure quantitatively and separately the effects of hypercapnia on the central and peripheral chemoreceptors, a... [more]
A technique, suitable for clinical practice, has been developed to measure quantitatively and separately the effects of hypercapnia on the central and peripheral chemoreceptors, and hypoxia on the peripheral chemoreceptors of a human subject. The technique uses a model to account for the dynamics of CO2 transport in the brain and is based on current concepts of the chemoreceptor system and makes a minimum of assumptions. The method was tested in one subject and there was evidence for hysteresis in the response to hypoxia and short-term adaptation in the response to hypercapnia of the chemoreceptor controller. © 1986.
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1985 |
CORMICK W, OLSON LG, HENSLEY MJ, SAUNDERS NA, 'NOCTURNAL HYPOXEMIA AND QUALITY OF SLEEP IN PATIENTS WITH CHRONIC AIR-FLOW LIMITATION (CAL)', AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 15 489-489 (1985) |
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1985 |
DOBSON AJ, FIRMAN DW, HELLER RF, HENSLEY MJ, LEEDER SR, 'CLINICAL EPIDEMIOLOGY IN THE DEVELOPING WORLD', COMMUNITY HEALTH STUDIES, 9 312-312 (1985) |
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1985 |
HENSLEY MJ, CLOVER KA, WLODARCZYK JH, BARRY RD, GLEESON M, FIRMAN DW, et al., 'RESPIRATORY ILLNESS AND IMMUNE DEVELOPMENT IN THE 1ST 5 YEARS OF LIFE', COMMUNITY HEALTH STUDIES, 9 321-321 (1985)
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1985 |
Cripps AW, Clancy RL, Gleeson M, Hensley MJ, Dobson AJ, Firman DW, 'The development of the mucosal immune response in man', Mucosal immunity, 275-276 (1985)
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1984 |
Tannock GA, Bryce DA, Hensley MJ, Saunders NA, Gillett RS, Kennedy WS, 'Responses to one or two doses of a deoxycholate subunit influenza vaccine in a primed population', Vaccine, 2 100-106 (1984)
A trial with a trivalent influenza subunit vaccine prepared with sodium deoxycholate was carried out in 88 volunteers between May and November 1981. Each haemagglutinin antigen wa... [more]
A trial with a trivalent influenza subunit vaccine prepared with sodium deoxycholate was carried out in 88 volunteers between May and November 1981. Each haemagglutinin antigen was present at 7 µg per dose. Fourfold or greater haemagglutination inhibition antibody (HI) responses to the H1N1 virus A/Brazil/11/78 occurred in 70% of the volunteers following a single dose. For the H3N2 virus A/Bangkok/1/79 and B/Singapore/222/79 these figures were 52 and 11%, respectively. No increase in the antibody titre was noted to any of the antigens following a second vaccination dose. Antibody levels remained relatively constant six months after vaccination. A response to B/Singapore/222/79, comparable with the HI response for the influenza A antigens, was noted when serum titres were estimated by a plaque reduction procedure. No neuraminidase inhibition antibody could be detected in response to either A/Brazil/11/78 or A/Bangkok/1/79. No reactions specifically attributable to the vaccine occurred after either injection. A lower HI response to A/Brazil/11/78 was noted in volunteers 52 years of age and older, who also showed less evidence of earlier priming to this virus. Levels of nasal wash neutralizing antibodies to A/Brazil/11/78 were proportional to those detected in sera by HI tests, but were present in smaller amounts. © 1984.
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Nova |
1984 |
Fowkes FGR, Dobson AJ, Hensley MJ, Leeder SR, 'The role of clinical epidemiology in medical practice', Effective Health Care, 1 259-265 (1984)
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1983 |
OLSON LG, HENSLEY MJ, SAUNDERS NA, 'BREATHING DURING SLEEP - THE RESPONSES TO ASPHYXIA AND PROCHLORPERAZINE IN NORMAL SUBJECTS AND PATIENTS WITH OBSTRUCTIVE SLEEP-APNEA', AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 13 613-620 (1983)
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1982 |
OLSON LG, HENSLEY MJ, SAUNDERS NA, 'VENTILATORY RESPONSIVENESS TO HYPERCAPNIC HYPOXIA DURING DOPAMINE INFUSION IN HUMANS', AMERICAN REVIEW OF RESPIRATORY DISEASE, 126 783-787 (1982)
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1982 |
OLSON LG, HENSLEY MJ, SAUNDERS NA, 'THE EFFECT OF PROCHLORPERAZINE (STEMETIL) ON THE VENTILATORY RESPONSE TO HYPOXIA IN MAN', AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 12 225-225 (1982) |
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1982 |
GLEESON M, CRIPPS AW, CLANCY RL, HUSBAND AJ, HENSLEY MJ, LEEDER SR, 'ONTOGENY OF THE SECRETORY IMMUNE-SYSTEM IN MAN', AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 12 255-258 (1982)
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1982 |
OLSON LG, HENSLEY MJ, SAUNDERS NA, 'AUGMENTATION OF VENTILATORY RESPONSE TO ASPHYXIA BY PROCHLORPERAZINE IN HUMANS', JOURNAL OF APPLIED PHYSIOLOGY, 53 637-643 (1982)
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1981 |
Leeder SR, Hensley MJ, Callaghan AF, Hardes GR, 'Preventing death from asthma', Australian Family Physician, 10 194-200 (1981)
Twenty-two deaths from asthma are examined. The majority of patients had experienced the asthma attack for some time; in spite of this, 73 per cent of the deaths occurred outside ... [more]
Twenty-two deaths from asthma are examined. The majority of patients had experienced the asthma attack for some time; in spite of this, 73 per cent of the deaths occurred outside hospital. Several of these may have been preventable.
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1981 |
Strohl KP, Hensley MJ, Saunders NA, Scharf SM, Brown R, Ingram RH, 'Progesterone Administration and Progressive Sleep Apneas', JAMA: The Journal of the American Medical Association, 245 1230-1232 (1981)
Nine adult patients with obstructive sleep apnea syndrome were administered medroxyprogesterone acetate, 60 to 120 mg/day, and the effect of medroxyprogesterone on clinical sympto... [more]
Nine adult patients with obstructive sleep apnea syndrome were administered medroxyprogesterone acetate, 60 to 120 mg/day, and the effect of medroxyprogesterone on clinical symptoms and obstructive apneas during sleep was assessed. Four patients responded with resolution of daytime sleepiness, disappearance of pedal edema, and a decrease in the number of obstructive apneas during sleep. Cessation of therapy led to a return of daytime sleepiness in three and an increase in obstructive apneas in all four subjects. Two responders experienced side effects of alopecia or decreased libido. Before medroxyprogesterone therapy, responders were distinguished from nonresponders only by the presence of a significantly lower resting arterial oxygen tension during wakefulness. We characterize a subgroup of patients who benefit from medroxyprogesterone therapy by reducing obstructive apneas during sleep. © 1981, American Medical Association. All rights reserved.
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1981 |
Strohl KP, Hensley MJ, Saunders NA, Scharf SM, Brown R, Ingram RH, 'Progesterone administration and progressive sleep apneas', Journal of the American Medical Association, 245 1230-1232 (1981)
Nine adult patients with obstructive sleep apnea syndrome were administered medroxyprogesterone acetate, 60 to 120 mg/day, and the effect of medroxyprogesterone on clinical sympto... [more]
Nine adult patients with obstructive sleep apnea syndrome were administered medroxyprogesterone acetate, 60 to 120 mg/day, and the effect of medroxyprogesterone on clinical symptoms and obstructive apneas during sleep was assessed. Four patients responded with resolution of daytime sleepiness, disappearance of pedal edema, and a decrease in the number of obstructive apneas during sleep. Cessation of therapy led to a return of daytime sleepiness in three and an increase in obstructive apneas in all four subjects. Two responders experienced side effects of alopecia or decreased libido. Before medroxyprogesterone therapy, responders were distinguished from nonresponders only by the presence of a significantly lower resting arterial oxygen tension during wakefulness. We characterize a subgroup of patients who benefit from medroxyprogesterone therapy by reducing obstructive apneas during sleep.
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1980 |
O'Cain CF, Dowling NB, Slutsky SA, Hensley MJ, Strohl KP, McFadden ER, Ingram RH, 'Airway effects of respiratory heat loss in normal subjects', Journal of Applied Physiology Respiratory Environmental and Exercise Physiology, 49 875-880 (1980)
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1980 |
Strohl KP, Hensley MJ, Hallett M, Saunders NA, Ingram RH, 'Activation of upper airway muscles before the onset of inspiration in normal humans', Journal of Applied Physiology Respiratory Environmental and Exercise Physiology, 49 638-642 (1980)
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1980 |
Hensley MJ, Saunders NA, Strohl KP, 'Medroxyprogesterone treatment of obstructive sleep apnoea', Sleep, 3 441-446 (1980)
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1979 |
O'Cain CF, Hensley MJ, McFadden ER, Ingram RH, 'Pattern and mechanism of airway response to hypocapnia in normal subjects', Journal of Applied Physiology Respiratory Environmental and Exercise Physiology, 47 8-12 (1979)
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1979 |
Hensley MJ, Feldman NT, Lazarus JM, Galvanek E, 'Diffuse pulmonary haemorrhage and acute renal failure. An uncommon presentation of Wegener's granulomatosis', American Journal of Medicine, 66 894-898 (1979)
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1979 |
Strohl KP, Brown R, Hensley MJ, 'Progesterone therapy for obstructive sleep apnea', American Review of Respiratory Disease, 119 173 (1979)
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1978 |
Hensley MJ, O'Cain CF, Ingram RJ, McFadden ER, 'Distribution of bronchodilation in normal subjects: beta-agonist versus atropine', Journal of Applied Physiology Respiratory Environmental and Exercise Physiology, 45 778-782 (1978)
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1978 |
Hensley MJ, O'Cain CF, Ingram RH, McFadden ER, 'Distribution of bronchodilatation with beta-adrenergic versus anti-cholinergic agents', Clinical Research, 26 (1978) |
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1977 |
Read D, Nickolls P, Hensley MJ, 'Instability of the carbon dioxide stimulus under the 'mixed venous isocapnic' conditions advocated for testing the ventilatory response to hypoxia', American Review of Respiratory Disease, 116 336-339 (1977)
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1977 |
Hensley MJ, Read DJC, 'A Test of the Ventilatory Response to Hypoxia and Hypercapnia for Clinical Use', Australian and New Zealand Journal of Medicine, 7 362-367 (1977)
Summary: A test of the ventilatory response to hypoxia and hypercapnia for clinical use. M. J. Hensley and D. J. C. Read, Aust. N.Z. J. Med., 1977, 7, pp. 362¿367. A new technique... [more]
Summary: A test of the ventilatory response to hypoxia and hypercapnia for clinical use. M. J. Hensley and D. J. C. Read, Aust. N.Z. J. Med., 1977, 7, pp. 362¿367. A new technique is described for testing the ventilatory response to hypoxia and to hypercapnia The test consists of interposing 15¿20 seconds of hypoxia in 3¿4 minutes of rebreathing 7% CO2; the hypoxia is induced by taking three to five breaths from a bag containing N2, and CO2 at an identical level. When required, hypoxic tests can be performed at several different PCO2 levels to define the interaction of hypoxic and hypercapnic stimuli In eight healthy subjects, 29 hypoxic tests were performed, at an average PCO2 of 58 mm Hg (range 53¿64). The correlation between ventilatory increments and 02-desaturation was significant in 27 of the 29 tests (r = 0.81-0.99). At the minimum 02-saturation (average 85%; range 75¿91%) there was a statistically significant ventilatory response to hypoxia in all 29 tests (average +60%; range +14 to +141%). At 90% O2-saturation, the average increment of ventilation was +48% This method has important theoretical and practical advantages for clinical studies: (i) the test involves only 15¿20 seconds of hypoxia; (ii) since the hypoxic drive to breathing is greatly enhanced by hypercapnia only a mild degree of hypoxaemia is necessary to obtain a clearly defined response; (iii) the augmented ventilation, produced by rebreathing, allows N2 to be rapidly introduced into the lungs without the need for voluntarily imposed deep breathing; (iv) the elevated PCO2 increases cerebral blood flow and minimises brain tissue hypoxia. (v) Since rebreathing 7% CO2 greatly reduces mixed venous-arterial and cerebral tissue-arterial PCO2 differences, the cerebral tissue PCO2 and CO2 stimulus are virtually unaffected by both ventilatory and cerebral blood flow responses in this test Copyright © 1977, Wiley Blackwell. All rights reserved
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1976 |
Hensley MJ, Read DJC, 'Intermittent Obstruction of the Upper Airway during Sleep Causing Profound Hypoxaemia. A Neglected Mechanism Exacerbating Chronic Respiratory Failure', Australian and New Zealand Journal of Medicine, 6 481-486 (1976)
Summary: Intermittent obstruction of the upper airway during sleep causing profound hypoxaemia. A neglected mechanism exacerbating chronic respiratory failure. An obese patient wi... [more]
Summary: Intermittent obstruction of the upper airway during sleep causing profound hypoxaemia. A neglected mechanism exacerbating chronic respiratory failure. An obese patient with a ten year history of respiratory failure presented with insomnia and marked daytime somnolence. Respiratory failure had been attributed to obesity, respiratory centre insensitivity to carbon dioxide, and to diffuse airways obstruction. To investigate the possible role of episodic apnoea with frequent nocturnal arousals, continuous recordings were obtained during sleep of arterial oxygen saturation, oesophageal pressure and the motions of the rib-cage and abdomen/diaphragm. Repeated episodes of hypoventilation and profound hypoxaemia were found which were due to intermittent obstruction of the upper airway rather than to cessation of breathing efforts. During the episodes of hypoxaemia, values of arterial 02 tension fell to as low as 24 mmHg. Episodic hypoxaemia was relieved but not abolished, by the use of a collar, designed to hold the mandible forward. Previous reports indicated that recognition of intermittent obstruction of the upper airway during sleep and treatment by a permanent tracheostomy, resulted in a significant long-term improvement of pulmonary and cardiac function and relief of insomnia and day-time somnolence. When tracheostomy is inadvisable, as in the present patient, it is hoped that similar long-term benefits will result from a supportive collar. Copyright © 1976, Wiley Blackwell. All rights reserved
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