
Conjoint Professor Robert Callister
Conjoint Professor
School of Biomedical Sciences and Pharmacy
- Email:robert.callister@newcastle.edu.au
- Phone:0438120954
Career Summary
Biography
Research Expertise
I am interested in the synaptic mechanisms involved in the processing of sensory signals in both the peripheral and central nervous system under normal and pathological conditions. Focus is on two sensory systems that are important clinically: pain and balance. Techniques used include patch clamp recording, in both in vitro (slices) and in vivo (deeply anaesthetized) preparations, and various immunohistochemical and cell labeling techniques. The mouse is used because this species allows us to make use of recent advances in molecular genetics. For example, various naturally occurring and transgenic mouse lines are used to better understand the role of ligand-gated ion channels (particularly, glycine receptors) in the processing of sensory signals under normal and pathological conditions.
Teaching Expertise
I have been involved in extensive face-to-face teaching for over 20 years at Ohio University, the University of Arizona and particularly at the University of Newcastle. I have delivered lectures at all levels of University instruction. I have taught extensively into all 14 Programs provided by the Faculty of Health at the University of Newcastle: human gross anatomy, histology, musculoskeletal anatomy, sectional and imaging anatomy, biomechanics, neuroanatomy, human physiology, neurophysiology and clinical neurophysiology. At Newcastle my teaching load has ranged from 120-220 contact hours each year into all programs offered by the Faculty of Health. It is emphasized that more than 70% of this load is lecture-based and delivered primarily to the later years of Medical, Biomedical Sciences, Speech Therapy, Physiotherapy and Medical Radiation Science Programs. My laboratory-based teaching is concentrated in specialized areas (neuroanatomy and neurophysiology, imaging, topographical anatomy).
Administrative Expertise
Head of Anatomy discipline, 1997-2002, 2008-present Co-ordinator of Faculty of Health Body Donor Program, 1998-2002, 2008-present Member of Bachelor of Biomedical Sciences Program Planning Committee, 1997-1998 Member of School of Biomedical Sciences Executive Committee, 1997-2002, 2009-2010 Member of Faculty Orientation Working Party, 1998 Member of Speech Pathology Program Curriculum Committee, 1999 Member of Link-Building Planning and Design Committee, 1998-2000 School Representative on Medicine and Health Sciences Faculty Board, 2000-2001 School Representative on Physiotherapy Program Design and Accreditation Committee, 2001 Faculty Representative on University OSPRO Committee, 2002-2007 Faculty Representative on Animal Care and Ethics Committee, (2005-2009).
Collaborations
Synaptic transmission in sensory pathways, specifically pathways associated with pain and balance disorders. Our group is interested in the way nerve cells communicate in the brain and spinal cord. We focus on nerve cell communication (synaptic transmission) in two sensory systems that are important clinically: those involved in pain syndromes and balance disorders. Techniques used include patch clamp recording, in both in vitro (spinal cord or brainstem slices) and in vivo (deeply anaesthetized) preparations, and various immunohistochemical and cell labelling techniques. We use the mouse as our animal model because this species allows us to make use of recent advances in molecular genetics to explore synaptic mechanisms. For example, various naturally occurring and transgenic mouse lines are used to better understand the role of ligand-gated ion channels (particularly, glycine and GABAA receptors) in the processing of sensory signals under normal and pathological conditions. Recently, our efforts have focused on excitability and synaptic mechanisms in ADULT mouse spinal cord slices and in anaesthetized mouse preparations. To our knowledge, our group is the only laboratory team capable of undertaking in vivo patch clamp recording in the spinal cord of a deeply anaesthetized mouse (see publications). This powerful approach allows the consequences of molecular and genetic discoveries/manipulations to be examined in BOTH spinal cord slices and in the intact animal.
Qualifications
- PhD, Ohio University - USA
- Bachelor of Pharmacy, University of Sydney
- Bachelor of Science (Honours), University of New South Wales
Keywords
- Anatomy
- Neuroscience
- Physiology
- glycine receptors
- motoneuron
- nerve cell excitability
- neurophysiology
- pain
- spinal cord
- synaptic transmission
Fields of Research
Code | Description | Percentage |
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111799 | Public Health and Health Services not elsewhere classified | 15 |
110999 | Neurosciences not elsewhere classified | 35 |
111699 | Medical Physiology not elsewhere classified | 50 |
Professional Experience
Membership
Dates | Title | Organisation / Department |
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Member - NHMRC Committee | Australian Neuroscience Society (ANS) Australia |
Professional appointment
Dates | Title | Organisation / Department |
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1/01/1976 - 1/08/1983 | Retail Pharmacist | Community practice in Sydney, NSW Manager Australia |
Awards
Recognition
Year | Award |
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2006 |
Research Higher Degree Supervisor of the Year, 2006 Faculty of Health, University of Newcastle |
Publications
For publications that are currently unpublished or in-press, details are shown in italics.
Chapter (4 outputs)
Year | Citation | Altmetrics | Link | ||||
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2012 |
Graham BA, Callister RJ, 'Pain', The Mouse Nervous System, Academic Press, San Diego 589-606 (2012) [B1]
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2001 |
Stuart DG, Pierce PA, Callister RJ, Brichta AM, McDonagh JC, 'Sir Charles Sherrington: Humanist, Mentor, and Movement Neuroscientist', Classics in Movement Science, Human Kinetics, U.S.A. 317-374 (2001) [B2]
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1999 |
McDonagh J, Callister RJ, Brichta AM, Stuart D, 'A commentary on the properties of spinal interneurons vs. motoneurons in vertebrates and their firing-rate behaviour during movement', Motor Control: Today and Tomorrow, Academic Publishing House "Prof.Marin Drinov", Sofia, Bulgaria 3-29 (1999) [B1]
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Show 1 more chapter |
Journal article (94 outputs)
Year | Citation | Altmetrics | Link | ||||||||
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2019 |
Gradwell MA, Callister RJ, Graham BA, 'Reviewing the case for compromised spinal inhibition in neuropathic pain.', J Neural Transm (Vienna), (2019)
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2019 |
Mayhew JA, Callister RJ, Walker FR, Smith DW, Graham BA, 'Aging alters signaling properties in the mouse spinal dorsal horn', MOLECULAR PAIN, 15 (2019) [C1]
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2019 |
Callister RJ, Brichta AM, Schaefer AT, Graham BA, Stuart DG, 'Pioneers in CNS inhibition: 2. Charles Sherrington and John Eccles on inhibition in spinal and supraspinal structures.', Brain Res, 146540 (2019)
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2019 |
Boyle KA, Gradwell MA, Yasaka T, Dickie AC, Polgár E, Ganley RP, et al., 'Defining a Spinal Microcircuit that Gates Myelinated Afferent Input: Implications for Tactile Allodynia', Cell Reports, 28 526-540.e6 (2019) [C1] © 2019 The Author(s) Chronic pain presents a major unmet clinical problem. The development of more effective treatments is hindered by our limited understanding of the neuronal ci... [more] © 2019 The Author(s) Chronic pain presents a major unmet clinical problem. The development of more effective treatments is hindered by our limited understanding of the neuronal circuits underlying sensory perception. Here, we show that parvalbumin (PV)-expressing dorsal horn interneurons modulate the passage of sensory information conveyed by low-threshold mechanoreceptors (LTMRs) directly via presynaptic inhibition and also gate the polysynaptic relay of LTMR input to pain circuits by inhibiting lamina II excitatory interneurons whose axons project into lamina I. We show changes in the functional properties of these PV interneurons following peripheral nerve injury and that silencing these cells unmasks a circuit that allows innocuous touch inputs to activate pain circuits by increasing network activity in laminae I¿IV. Such changes are likely to result in the development of tactile allodynia and could be targeted for more effective treatment of mechanical pain. In this study, Boyle et al. identify parvalbumin-expressing spinal interneurons as a principal source of axoaxonic synapses onto cutaneous myelinated afferents and inhibitory inputs onto lamina II vertical cells. Following peripheral nerve injury, disinhibition of these targets facilitates the aberrant recruitment of pain circuits, leading to tactile allodynia.
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2019 |
de Oliveira RB, Petiz LL, Lim R, Lipski J, Gravina FS, Brichta AM, et al., 'Crosstalk between mitochondria, calcium channels and actin cytoskeleton modulates noradrenergic activity of locus coeruleus neurons.', Journal of neurochemistry, 149 471-487 (2019) [C1]
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2019 |
Smith KM, Browne TJ, Davis OC, Coyle A, Boyle KA, Watanabe M, et al., 'Calretinin positive neurons form an excitatory amplifier network in the spinal cord dorsal horn.', Elife, 8 (2019)
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2018 |
Rank MM, Galea MP, Callister R, Callister RJ, 'Is more always better? How different doses of exercise after incomplete spinal cord injury affects the membrane properties of deep dorsal horn interneurons', Experimental Neurology, 300 201-211 (2018) [C1] © 2017 Elsevier Inc. Interneurons in the deep dorsal horn (DDH) of the spinal cord process somatosensory input, and form an important link between upper and lower motoneurons to s... [more] © 2017 Elsevier Inc. Interneurons in the deep dorsal horn (DDH) of the spinal cord process somatosensory input, and form an important link between upper and lower motoneurons to subsequently shape motor output. Exercise training after SCI is known to improve functional motor recovery, but little is known about the mechanisms within spinal cord neurons that underlie these improvements. Here we investigate how the properties of DDH interneurons are affected by spinal cord injury (SCI) alone, and SCI in combination with different ¿doses¿ of treadmill exercise training (3, 6, and 9 wks). In an adult mouse hemisection model of SCI we used whole-cell patch-clamp electrophysiology to record intrinsic, AP firing and gain modulation properties from DDH interneurons in a horizontal spinal cord slice preparation. We find that neurons within two segments of the injury, both ipsi- and contralateral to the hemisection, are similarly affected by SCI and SCI plus exercise. The passive intrinsic membrane properties input resistance (Rin) and rheobase are sensitive to the effects of recovery time and exercise training after SCI thus altering DDH interneuron excitability. Conversely, select active membrane properties are largely unaffected by either SCI or exercise training. SCI itself causes a mismatch in the expression of voltage-gated subthreshold currents and AP discharge firing type. Over time after SCI, and especially with exercise training (9 wks), this mismatched expression is exacerbated. Lastly, amplification properties (i.e. gain of frequency-current relationship) of DDH interneurons are altered by SCI alone and recover spontaneously with no clear effect of exercise training. These results suggest a larger ¿dose¿ of exercise training (9 wks) has a strong and selective effect on specific membrane properties, and on the output of interneurons in the vicinity of a SCI. These electrophysiological data provide new insights into the plasticity of DDH interneurons and the mechanisms by which exercise therapy after SCI can improve recovery.
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2018 |
Mateer SW, Mathe A, Bruce J, Liu G, Maltby S, Fricker M, et al., 'IL-6 Drives Neutrophil-Mediated Pulmonary Inflammation Associated with Bacteremia in Murine Models of Colitis', American Journal of Pathology, 188 1625-1639 (2018) [C1] © 2018 American Society for Investigative Pathology Inflammatory bowel disease (IBD) is associated with several immune-mediated extraintestinal manifestations. More than half of a... [more] © 2018 American Society for Investigative Pathology Inflammatory bowel disease (IBD) is associated with several immune-mediated extraintestinal manifestations. More than half of all IBD patients have some form of respiratory pathology, most commonly neutrophil-mediated diseases, such as bronchiectasis and chronic bronchitis. Using murine models of colitis, we aimed to identify the immune mechanisms driving pulmonary manifestations of IBD. We found increased neutrophil numbers in lung tissue associated with the pulmonary vasculature in both trinitrobenzenesulfonic acid¿ and dextran sulfate sodium¿induced models of colitis. Analysis of systemic inflammation identified that neutrophilia was associated with bacteremia and pyrexia in animal models of colitis. We further identified IL-6 as a systemic mediator of neutrophil recruitment from the bone marrow of dextran sulfate sodium animals. Functional inhibition of IL-6 led to reduced systemic and pulmonary neutrophilia, but it did not attenuate established colitis pathology. These data suggest that systemic bacteremia and pyrexia drive IL-6 secretion, which is a critical driver for pulmonary manifestation of IBD. Targeting IL-6 may reduce neutrophil-associated extraintestinal manifestations in IBD patients.
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2018 |
Poppi LA, Tabatabaee H, Drury HR, Jobling P, Callister RJ, Migliaccio AA, et al., 'ACh-induced hyperpolarization and decreased resistance in mammalian type II vestibular hair cells', Journal of Neurophysiology, 119 312-325 (2018) [C1] © 2018 American Physiological Society. All rights reserved. In the mammalian vestibular periphery, electrical activation of the efferent vestibular system (EVS) has two effects o... [more] © 2018 American Physiological Society. All rights reserved. In the mammalian vestibular periphery, electrical activation of the efferent vestibular system (EVS) has two effects on afferent activity: 1) it increases background afferent discharge and 2) decreases afferent sensitivity to rotational stimuli. Although the cellular mechanisms underlying these two contrasting afferent responses remain obscure, we postulated that the reduction in afferent sensitivity was attributed, in part, to the activation of a9- containing nicotinic acetylcholine (ACh) receptors (a9*nAChRs) and small-conductance potassium channels (SK) in vestibular type II hair cells, as demonstrated in the peripheral vestibular system of other vertebrates. To test this hypothesis, we examined the effects of the predominant EVS neurotransmitter ACh on vestibular type II hair cells from wild-type (wt) and a9-subunit nAChR knockout (a9 -/- ) mice. Immunostaining for choline acetyltransferase revealed there were no obvious gross morphological differences in the peripheral EVS innervation among any of these strains. ACh application onto wt type II hair cells, at resting potentials, produced a fast inward current followed by a slower outward current, resulting in membrane hyperpolarization and decreased membrane resistance. Hyperpolarization and decreased resistance were due to gating of SK channels. Consistent with activation of a9*nAChRs and SK channels, these ACh-sensitive currents were antagonized by the a9*nAChR blocker strychnine and SK blockers apamin and tamapin. Type II hair cells from a9 -/- mice, however, failed to respond to ACh at all. These results confirm the critical importance of a9nAChRs in efferent modulation of mammalian type II vestibular hair cells. Application of exogenous ACh reduces electrical impedance, thereby decreasing type II hair cell sensitivity. NEW & NOTEWORTHY Expression of a9 nicotinic subunit was crucial for fast cholinergic modulation of mammalian vestibular type II hair cells. These findings show a multifaceted efferent mechanism for altering hair cell membrane potential and decreasing membrane resistance that should reduce sensitivity to hair bundle displacements.
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2018 |
Tadros MA, Zouikr I, Hodgson DM, Callister RJ, 'Excitability of rat superficial dorsal horn neurons following a neonatal immune challenge', Frontiers in Neurology, 9 (2018) [C1]
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2017 |
Gradwell MA, Boyle KA, Callister RJ, Hughes DI, Graham BA, 'Heteromeric a/ß glycine receptors regulate excitability in parvalbumin-expressing dorsal horn neurons through phasic and tonic glycinergic inhibition', Journal of Physiology, 595 7185-7202 (2017) [C1] © 2017 The Authors. The Journal of Physiology published by John Wiley & Sons Ltd on behalf of The Physiological Society Key points: Spinal parvalbumin-expressing interneuron... [more] © 2017 The Authors. The Journal of Physiology published by John Wiley & Sons Ltd on behalf of The Physiological Society Key points: Spinal parvalbumin-expressing interneurons have been identified as a critical source of inhibition to regulate sensory thresholds by gating mechanical inputs in the dorsal horn. This study assessed the inhibitory regulation of the parvalbumin-expressing interneurons, showing that synaptic and tonic glycinergic currents dominate, blocking neuronal or glial glycine transporters enhances tonic glycinergic currents, and these manipulations reduce excitability. Synaptically released glycine also enhanced tonic glycinergic currents and resulted in decreased parvalbumin-expressing interneuron excitability. Analysis of the glycine receptor properties mediating inhibition of parvalbumin neurons, as well as single channel recordings, indicates that heteromeric a/ß subunit-containing receptors underlie both synaptic and tonic glycinergic currents. Our findings indicate that glycinergic inhibition provides critical control of excitability in parvalbumin-expressing interneurons in the dorsal horn and represents a pharmacological target to manipulate spinal sensory processing. Abstract: The dorsal horn (DH) of the spinal cord is an important site for modality-specific processing of sensory information and is essential for contextually relevant sensory experience. Parvalbumin-expressing inhibitory interneurons (PV+ INs) have functional properties and connectivity that enables them to segregate tactile and nociceptive information. Here we examine inhibitory drive to PV+ INs using targeted patch-clamp recording in spinal cord slices from adult transgenic mice that express enhanced green fluorescent protein in PV+ INs. Analysis of inhibitory synaptic currents showed glycinergic transmission is the dominant form of phasic inhibition to PV+ INs. In addition, PV+ INs expressed robust glycine-mediated tonic currents; however, we found no evidence for tonic GABAergic currents. Manipulation of extracellular glycine by blocking either, or both, the glial and neuronal glycine transporters markedly decreased PV+ IN excitability, as assessed by action potential discharge. This decreased excitability was replicated when tonic glycinergic currents were increased by electrically activating glycinergic synapses. Finally, we show that both phasic and tonic forms of glycinergic inhibition are mediated by heteromeric a/ß glycine receptors. This differs from GABAA receptors in the dorsal horn, where different receptor stoichiometries underlie phasic and tonic inhibition. Together these data suggest both phasic and tonic glycinergic inhibition regulate the output of PV+ INs and contribute to the processing and segregation of tactile and nociceptive information. The shared stoichiometry for phasic and tonic glycine receptors suggests pharmacology is unlikely to be able to selectively target each form of inhibition in PV+ INs.
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2017 |
Farrell KE, Keely S, Walker MM, Brichta AM, Graham BA, Callister RJ, 'Altered intrinsic and synaptic properties of lumbosacral dorsal horn neurons in a mouse model of colitis', Neuroscience, 362 152-167 (2017) [C1] © 2017 IBRO Visceral pain in inflammatory and functional gastrointestinal conditions is a major clinical problem. The exact mechanisms underlying the development of pain, during a... [more] © 2017 IBRO Visceral pain in inflammatory and functional gastrointestinal conditions is a major clinical problem. The exact mechanisms underlying the development of pain, during and after visceral inflammation are unknown. However, clinical and pre-clinical evidence suggests plasticity within the spinal cord dorsal horn is a contributing factor. Here we use an in vivo preparation and patch-clamp electrophysiology to test whether the synaptic and intrinsic properties of superficial dorsal horn (SDH) neurons are altered 5 days after the induction of mild colitis in adult male mice (i.e. during acute inflammation of the colon). Whole-cell recordings were made from lumbosacral (L6-S1) superficial dorsal horn neurons (SDH), in animals under isoflurane anesthesia. Noxious colorectal distension (CRD) was used to identify SDH neurons with colonic inputs, while stimulation of the hind paw and tail was employed to assess convergent cutaneous input. Following inflammation, a significantly increased proportion of SDH neurons received both colonic and cutaneous inputs, compared to neurons in naïve animals. In addition, the nature and magnitude of responses to CRD and cutaneous stimulation differed in inflamed animals, as was spontaneous excitatory synaptic drive. Conversely, several measures of intrinsic excitability were altered in a manner that would decrease SDH network excitability following colitis. We propose that during inflammation, sensitization of colonic afferents results in increased signaling to the SDH. This is accompanied by plasticity in SDH neurons whereby their intrinsic properties are changed to compensate for altered afferent activity.
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2017 |
Battistuzzo CR, Rank MM, Flynn JR, Morgan DL, Callister R, Callister RJ, Galea MP, 'Effects Of treadmill training on hindlimb muscles of spinal cord injured mice', Muscle and Nerve, 55 232-242 (2017) [C1]
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2017 |
Flynn JR, Conn VL, Boyle KA, Hughes DI, Watanabe M, Velasquez T, et al., 'Anatomical and Molecular Properties of Long Descending Propriospinal Neurons in Mice', FRONTIERS IN NEUROANATOMY, 11 (2017) [C1]
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2017 |
Marks E, Naudin C, Nolan G, Goggins BJ, Burns G, Mateer SW, et al., 'Regulation of IL-12p40 by HIF controls Th1/Th17 responses to prevent mucosal inflammation', MUCOSAL IMMUNOLOGY, 10 1224-1236 (2017) [C1]
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2016 |
Tadros MA, Fuglevand AJ, Brichta AM, Callister RJ, 'Intrinsic excitability differs between murine hypoglossal and spinal motoneurons.', Journal of neurophysiology, 115 2672-2680 (2016) [C1]
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2016 |
Farrell KE, Rank MM, Keely S, Brichta AM, Graham BA, Callister RJ, 'In vivo characterization of colorectal and cutaneous inputs to lumbosacral dorsal horn neurons in the mouse spinal cord', Neuroscience, 316 13-25 (2016) [C1] © 2015 IBRO. Chronic abdominal pain is a common symptom of inflammatory bowel disease and often persists in the absence of gut inflammation. Although the mechanisms responsible fo... [more] © 2015 IBRO. Chronic abdominal pain is a common symptom of inflammatory bowel disease and often persists in the absence of gut inflammation. Although the mechanisms responsible for ongoing pain are unknown, clinical and preclinical evidence suggests lumbosacral spinal cord dorsal horn neurons contribute to these symptoms. At present, we know little about the intrinsic and synaptic properties of this population of neurons in either normal or inflammed conditions. Therefore, we developed an in vivo preparation to make patch-clamp recordings from superficial dorsal horn (SDH) neurons receiving colonic inputs in naïve male mice. Recordings were made in the lumbosacral spinal cord (L6-S1) under isoflurane anesthesia. Noxious colorectal distension (CRD) was used to determine whether SDH neurons received inputs from mechanical stimulation/distension of the colon. Responses to hind paw/tail cutaneous stimulation and intrinsic and synaptic properties were also assessed, as well as action potential discharge properties. Approximately 11% of lumbosacral SDH neurons in the cohort of neurons sampled responded to CRD and a majority of these responses were subthreshold. Most CRD-responsive neurons (80%) also responded to cutaneous stimuli, compared with <50% of CRD-non-responsive neurons. Furthermore, CRD-responsive neurons had more hyperpolarized resting membrane potentials, larger rheobase currents, and reduced levels of excitatory drive, compared to CRD-non-responsive neurons. Our results demonstrate that CRD-responsive neurons can be distinguished from CRD-non-responsive neurons by several differences in their membrane properties and excitatory synaptic inputs. We also demonstrate that SDH neurons with colonic inputs show predominately subthreshold responses to CRD and exhibit a high degree of viscerosomatic convergence.
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2016 |
Battistuzzo CR, Rank MM, Flynn JR, Morgan DL, Callister R, Callister RJ, Galea MP, 'Gait recovery following spinal cord injury in mice: Limited effect of treadmill training', Journal of Spinal Cord Medicine, 39 335-343 (2016) [C1] © 2016, © The Academy of Spinal Cord Injury Professionals, Inc. 2016. Several studies in rodents with complete spinal cord transections have demonstrated that treadmill training i... [more] © 2016, © The Academy of Spinal Cord Injury Professionals, Inc. 2016. Several studies in rodents with complete spinal cord transections have demonstrated that treadmill training improves stepping movements. However, results from studies in incomplete spinal cord injured animals have been conflicting and questions regarding the training dosage after injury remain unresolved. Objectives: To assess the effects of treadmill-training regimen (20 minutes daily, 5 days a week) for 3, 6 or 9 weeks on the recovery of locomotion in hemisected SCI mice. Methods: A randomized and blinded controlled experimental trial used a mouse model of incomplete spinal cord injury (SCI). After a left hemisection at T10, adult male mice were randomized to trained or untrained groups. The trained group commenced treadmill training one week after surgery and continued for 3, 6 or 9 weeks. Quantitative kinematic gait analysis was used to assess the spatiotemporal characteristics of the left hindlimb prior to injury and at 1, 4, 7 and 10 weeks post-injury. Results: One week after injury there was no movement of the left hindlimb and some animals dragged their foot. Treadmill training led to significant improvements in step duration, but had limited effect on the hindlimb movement pattern. Locomotor improvements in trained animals were most evident at the hip and knee joints whereas recovery of ankle movement was limited, even after 9 weeks of treadmill training. Conclusion: These results demonstrate that treadmill training may lead to only modest improvement in recovery of hindlimb movement after incomplete spinal cord injury in mice.
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2016 |
Smith KM, Boyle KA, Mustapa M, Jobling P, Callister RJ, Hughes DI, Graham BA, 'Distinct forms of synaptic inhibition and neuromodulation regulate calretinin-positive neuron excitability in the spinal cord dorsal horn', Neuroscience, 326 10-21 (2016) [C1] © 2016 . The dorsal horn (DH) of the spinal cord contains a heterogenous population of neurons that process incoming sensory signals before information ascends to the brain. We ha... [more] © 2016 . The dorsal horn (DH) of the spinal cord contains a heterogenous population of neurons that process incoming sensory signals before information ascends to the brain. We have recently characterized calretinin-expressing (CR+) neurons in the DH and shown that they can be divided into excitatory and inhibitory subpopulations. The excitatory population receives high-frequency excitatory synaptic input and expresses delayed firing action potential discharge, whereas the inhibitory population receives weak excitatory drive and exhibits tonic or initial bursting discharge. Here, we characterize inhibitory synaptic input and neuromodulation in the two CR+ populations, in order to determine how each is regulated. We show that excitatory CR+ neurons receive mixed inhibition from GABAergic and glycinergic sources, whereas inhibitory CR+ neurons receive inhibition, which is dominated by glycine. Noradrenaline and serotonin produced robust outward currents in excitatory CR+ neurons, predicting an inhibitory action on these neurons, but neither neuromodulator produced a response in CR+ inhibitory neurons. In contrast, enkephalin (along with selective mu and delta opioid receptor agonists) produced outward currents in inhibitory CR+ neurons, consistent with an inhibitory action but did not affect the excitatory CR+ population. Our findings show that the pharmacology of inhibitory inputs and neuromodulator actions on CR+ cells, along with their excitatory inputs can define these two subpopulations further, and this could be exploited to modulate discrete aspects of sensory processing selectively in the DH.
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2015 |
Rank MM, Flynn JR, Battistuzzo CR, Galea MP, Callister R, Callister RJ, 'Functional changes in deep dorsal horn interneurons following spinal cord injury are enhanced with different durations of exercise training', JOURNAL OF PHYSIOLOGY-LONDON, 593 331-345 (2015) [C1]
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2015 |
Rank MM, Flynn JR, Galea MP, Callister R, Callister RJ, 'Electrophysiological characterization of spontaneous recovery in deep dorsal horn interneurons after incomplete spinal cord injury', Experimental Neurology, 271 468-478 (2015) [C1] © 2015 Elsevier Inc. In the weeks and months following an incomplete spinal cord injury (SCI) significant spontaneous recovery of function occurs in the absence of any applied the... [more] © 2015 Elsevier Inc. In the weeks and months following an incomplete spinal cord injury (SCI) significant spontaneous recovery of function occurs in the absence of any applied therapeutic intervention. The anatomical correlates of this spontaneous plasticity are well characterized, however, the functional changes that occur in spinal cord interneurons after injury are poorly understood. Here we use a T10 hemisection model of SCI in adult mice (9-10 wks old) combined with whole-cell patch clamp electrophysiology and a horizontal spinal cord slice preparation to examine changes in intrinsic membrane and synaptic properties of deep dorsal horn (DDH) interneurons. We made these measurements during short-term (4 wks) and long-term (10 wks) spontaneous recovery after SCI. Several important intrinsic membrane properties are altered in the short-term, but recover to values resembling those of uninjured controls in the longer term. AP discharge patterns are reorganized at both short-term and long-term recovery time points. This is matched by reorganization in the expression of voltage-activated potassium and calcium subthreshold-currents that shape AP discharge. Excitatory synaptic inputs onto DDH interneurons are significantly restructured in long-term SCI mice. Plots of sEPSC peak amplitude vs. rise times suggest considerable dendritic expansion or synaptic reorganization occurs especially during long-term recovery from SCI. Connectivity between descending dorsal column pathways and DDH interneurons is reduced in the short-term, but amplified in long-term recovery. Our results suggest considerable plasticity in both intrinsic and synaptic mechanisms occurs spontaneously in DDH interneurons following SCI and takes a minimum of 10 wks after the initial injury to stabilize.
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2015 |
Tadros MA, Lim R, Hughes DI, Brichta AM, Callister RJ, 'Electrical maturation of spinal neurons in the human fetus: Comparison of ventral and dorsal horn', Journal of Neurophysiology, 114 2661-2671 (2015) [C1] © 2015 the American Physiological Society. The spinal cord is critical for modifying and relaying sensory information to, and motor commands from, higher centers in the central ne... [more] © 2015 the American Physiological Society. The spinal cord is critical for modifying and relaying sensory information to, and motor commands from, higher centers in the central nervous system to initiate and maintain contextually relevant locomotor responses. Our understanding of how spinal sensorimotor circuits are established during in utero development is based largely on studies in rodents. In contrast, there is little functional data on the development of sensory and motor systems in humans. Here, we use patch-clamp electrophysiology to examine the development of neuronal excitability in human fetal spinal cords (10¿18 wk gestation; WG). Transverse spinal cord slices (300 µm thick) were prepared, and recordings were made, from visualized neurons in either the ventral (VH) or dorsal horn (DH) at 32°C. Action potentials (APs) could be elicited in VH neurons throughout the period examined, but only after 16 WG in DH neurons. At this age, VH neurons discharged multiple APs, whereas most DH neurons discharged single APs. In addition, at 16¿18 WG, VH neurons also displayed larger AP and after-hyperpolarization amplitudes than DH neurons. Between 10 and 18 WG, the intrinsic properties of VH neurons changed markedly, with input resistance decreasing and AP and after-hyperpolarization amplitudes increasing. These findings are consistent with the hypothesis that VH motor circuitry matures more rapidly than the DH circuits that are involved in processing tactile and nociceptive information.
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2015 |
Tadros MA, Farrell KE, Graham BA, Brichta AM, Callister RJ, 'Properties of sodium currents in neonatal and young adult mouse superficial dorsal horn neurons', Molecular Pain, 11 (2015) [C1] © Tadros et al.; licensee BioMed Central. Background: Superficial dorsal horn (SDH) neurons process nociceptive information and their excitability is partly determined by the prop... [more] © Tadros et al.; licensee BioMed Central. Background: Superficial dorsal horn (SDH) neurons process nociceptive information and their excitability is partly determined by the properties of voltage-gated sodium channels. Recently, we showed the excitability and action potential properties of mouse SDH neurons change markedly during early postnatal development. Here we compare sodium currents generated in neonate (P0-5) and young adult (=P21) SDH neurons. Results: Whole cell recordings were obtained from lumbar SDH neurons in transverse spinal cord slices (CsF internal, 32°C). Fast activating and inactivating TTX-sensitive inward currents were evoked by depolarization from a holding potential of 100mV. Poorly clamped currents, based on a deflection in the IV relationship at potentials between 60 and 50mV, were not accepted for analysis. Current density and decay time increased significantly between the first and third weeks of postnatal development, whereas time to peak was similar at both ages. This was accompanied by more subtle changes in activation range and steady state inactivation. Recovery from inactivation was slower and TTX-sensitivity was reduced in young adult neurons. Conclusions: Our study suggests sodium channel expression changes markedly during early postnatal development in mouse SDH neurons. The methods employed in this study can now be applied to future investigations of spinal cord sodium channel plasticity in murine pain models.
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2015 |
Callister RJ, Graham BA, 'Spicing up the gabapentionoids: Facilitating gabapentin entry in spinal pain circuits', Neuroscience Letters, 584 395-396 (2015) [C3]
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2015 |
Smith KM, Boyle KA, Madden JF, Dickinson SA, Jobling P, Callister RJ, et al., 'Functional heterogeneity of calretinin-expressing neurons in the mouse superficial dorsal horn: Implications for spinal pain processing', Journal of Physiology, 593 4319-4339 (2015) [C1] © 2015 The Physiological Society. Neurons in the superficial dorsal horn (SDH) of the spinal cord play an important role in nociceptive, thermal, itch and light touch sensations. ... [more] © 2015 The Physiological Society. Neurons in the superficial dorsal horn (SDH) of the spinal cord play an important role in nociceptive, thermal, itch and light touch sensations. Excitatory interneurons comprise ~65% of all SDH neurons but surprisingly few studies have investigated their role in spinal sensory processing. Here we use a transgenic mouse to study putative excitatory SDH neurons that express the calcium binding protein calretinin (CR). Our immunocytochemical, morphological and electrophysiological analysis identified two distinct populations of CR-expressing neurons, which we termed 'Typical' and 'Atypical'. Typical CR-expressing neurons comprised ~85% of the population and exhibited characteristic excitatory interneuron properties including delayed firing discharge, large rapid A-type potassium currents, and central, radial or vertical cell morphologies. Atypical neurons exhibited properties consistent with inhibitory interneurons, including tonic firing or initial bursting discharge, Ih currents, and islet cell morphology. Although both Typical and Atypical CR-expressing neurons responded to noxious peripheral stimulation, the excitatory drive onto Typical CR-expressing neurons was much stronger. Furthermore, Atypical CR-expressing cells comprise at least two functionally distinct subpopulations based on their responsiveness to noxious peripheral stimulation and neurochemical profile. Together our data suggest CR expression is not restricted to excitatory neurons in the SDH. Under normal conditions, the contribution of 'Typical' excitatory CR-expressing neurons to overall SDH excitability may be limited by the presence of A-type potassium currents, which limit the effectiveness of their strong excitatory input. Their contribution may, however, be increased in pathological situations where A-type potassium currents are decreased. By contrast, 'Atypical' inhibitory neurons with their excitable phenotype but weak excitatory input may be more easily recruited during increased peripheral stimulation.
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2014 |
Tadros MA, Farrell KE, Schofield PR, Brichta AM, Graham BA, Fuglevand AJ, Callister RJ, 'Intrinsic and synaptic homeostatic plasticity in motoneurons from mice with glycine receptor mutations', Journal of Neurophysiology, 111 1487-1498 (2014) [C1] Inhibitory synaptic inputs to hypoglossal motoneurons (HMs) are important for modulating excitability in brainstem circuits. Here we ask whether reduced inhibition, as occurs in t... [more] Inhibitory synaptic inputs to hypoglossal motoneurons (HMs) are important for modulating excitability in brainstem circuits. Here we ask whether reduced inhibition, as occurs in three murine mutants with distinct naturally occurring mutations in the glycine receptor (GlyR), leads to intrinsic and/or synaptic homeostatic plasticity. Whole cell recordings were obtained from HMs in transverse brainstem slices from wild-type (wt), spasmodic (spd), spastic (spa), and oscillator (ot) mice (C57Bl/6, approximately postnatal day 21). Passive and action potential (AP) properties in spd and ot HMs were similar to wt. In contrast, spa HMs had lower input resistances, more depolarized resting membrane potentials, higher rheobase currents, smaller AP amplitudes, and slower afterhyperpolarization current decay times. The excitability of HMs, assessed by "gain" in injected current/firing-frequency plots, was similar in all strains whereas the incidence of rebound spiking was increased in spd. The difference between recruitment and derecruitment current (i.e., ¿I) for AP discharge during ramp current injection was more negative in spa and ot. GABAA miniature inhibitory postsynaptic current (mIPSC) amplitude was increased in spa and ot but not spd, suggesting diminished glycinergic drive leads to compensatory adjustments in the other major fast inhibitory synaptic transmitter system in these mutants. Overall, our data suggest long-term reduction in glycinergic drive to HMs results in changes in intrinsic and synaptic properties that are consistent with homeostatic plasticity in spa and ot but not in spd. We propose such plasticity is an attempt to stabilize HM output, which succeeds in spa but fails in ot. © 2014 the American Physiological Society.
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2014 |
Zouikr I, Tadros MA, Barouei J, Beagley KW, Clifton VL, Callister RJ, Hodgson DM, 'Altered nociceptive, endocrine, and dorsal horn neuron responses in rats following a neonatal immune challenge', PSYCHONEUROENDOCRINOLOGY, 41 1-12 (2014) [C1]
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2014 |
Farrell KE, Keely S, Graham BA, Callister R, Callister RJ, 'A Systematic Review of the Evidence for Central Nervous System Plasticity in Animal Models of Inflammatory-mediated Gastrointestinal Pain', INFLAMMATORY BOWEL DISEASES, 20 176-195 (2014) [C1]
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2014 |
Lim R, Drury HR, Tadros MA, Callister RJ, Brichta AM, Camp AJ, 'Preliminary Characterization of Voltage-Activated Whole-Cell Currents in Developing Human Vestibular Hair Cells and Calyx Afferent Terminals', Journal of the Association for Research in Otolaryngology, (2014) [C1] We present preliminary functional data from human vestibular hair cells and primary afferent calyx terminals during fetal development. Whole-cell recordings were obtained from hai... [more] We present preliminary functional data from human vestibular hair cells and primary afferent calyx terminals during fetal development. Whole-cell recordings were obtained from hair cells or calyx terminals in semi-intact cristae prepared from human fetuses aged between 11 and 18 weeks gestation (WG). During early fetal development (11-14 WG), hair cells expressed whole-cell conductances that were qualitatively similar but quantitatively smaller than those observed previously in mature rodent type II hair cells. As development progressed (15-18 WG), peak outward conductances increased in putative type II hair cells but did not reach amplitudes observed in adult human hair cells. Type I hair cells express a specific low-voltage activating conductance, G. A similar current was first observed at 15 WG but remained relatively small, even at 18 WG. The presence of a "collapsing" tail current indicates a maturing type I hair cell phenotype and suggests the presence of a surrounding calyx afferent terminal. We were also able to record from calyx afferent terminals in 15-18 WG cristae. In voltage clamp, these terminals exhibited fast inactivating inward as well as slower outward conductances, and in current clamp, discharged a single action potential during depolarizing steps. Together, these data suggest the major functional characteristics of type I and type II hair cells and calyx terminals are present by 18 WG. Our study also describes a new preparation for the functional investigation of key events that occur during maturation of human vestibular organs. © 2014 The Author(s).
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2014 |
Farrell KE, Callister RJ, Keely S, 'Understanding and targeting centrally mediated visceral pain in inflammatory bowel disease', Frontiers in Pharmacology, 5 1-4 (2014) [C3]
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2014 |
Harris BM, Hughes DI, Bolton PS, Tadros MA, Callister RJ, Graham BA, 'Contrasting alterations to synaptic and intrinsic properties in upper-cervical superficial dorsal horn neurons following acute neck muscle inflammation', MOLECULAR PAIN, 10 (2014) [C1]
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2014 |
Stuart DG, Schaefer AT, Massion J, Graham BA, Callister RJ, 'Pioneers in CNS inhibition: 1. Ivan M. Sechenov, the first to clearly demonstrate inhibition arising in the brain', Brain Research, 1548 20-48 (2014) [C1] This article reviews the contributions of Ivan Michailovich Sechenov [1829-1905] to the neurophysiological concept of central inhibition. He first studied this concept in the frog... [more] This article reviews the contributions of Ivan Michailovich Sechenov [1829-1905] to the neurophysiological concept of central inhibition. He first studied this concept in the frog and on himself. Later his trainees extended the study of central inhibition to other mammalian species. Outside his own country, Sechenov is better known for his prescient contributions to physiological psychology. In Russia, however, he is also revered as "the father of Russian physiology," because of his contributions to neurophysiology and other aspects of physiology including blood gases and respiration, the physiology and biomechanics of movement, and general physiology concepts that appeared in his textbooks and later works he helped translate from largely German sources. After graduation from Moscow University Medical School in 1856 he spent 31/2 years in Germany and Austria where he attended lectures and conducted research under the direction of several prominent physiologists and biochemists. In his subsequent academic career he held positions at universities in St. Petersburg (1860-1870; 1876-1888), Odessa (1871-1876) and Moscow (1890-1905). From 1860 onwards he was acclaimed as a physiologist in academic circles. He was also well known in Russian society for his public lectures on physiology and his views on physiological psychology. The latter resulted in him being branded "politically unreliable" by the tsarist bureaucracy from 1863 onwards. Sechenov's first (1862) study on central inhibition remains his most memorable. He delayed the withdrawal of a frog's foot from a weak acid solution by chemical or electrical stimulation of selected parts of the central nervous system. He also noted similar effects on his own hand during co-activation of other sensory inputs by tickling or teeth gnashing. © 2013 Elsevier B.V. All rights reserved.
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2014 |
Smith KM, Madden JF, Callister RJ, Hughes DI, Graham BA, 'The search for novel analgesics: re-examining spinal cord circuits with new tools.', Front Pharmacol, 5 22 (2014) [C1]
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2014 |
Pursey KM, Stanwell PT, Callister RJ, Brain K, Collins CE, Burrows TL, 'Neural responses to visual food cues according to weight status: a systematic review of functional magnetic resonance imaging studies', Frontiers in Nutrition, 1 1-11 (2014) [C1]
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2013 |
Hughes DI, Boyle KA, Kinnon CM, Bilsland C, Quayle JA, Callister RJ, Graham BA, 'HCN4 subunit expression in fast-spiking interneurons of the rat spinal cord and hippocampus', Neuroscience, 237 7-18 (2013) [C1] Hyperpolarisation-activated (Ih) currents are considered important for dendritic integration, synaptic transmission, setting membrane potential and rhythmic action potential (AP) ... [more] Hyperpolarisation-activated (Ih) currents are considered important for dendritic integration, synaptic transmission, setting membrane potential and rhythmic action potential (AP) discharge in neurons of the central nervous system. Hyperpolarisation-activated cyclic nucleotide-gated (HCN) channels underlie these currents and are composed of homo- and hetero-tetramers of HCN channel subunits (HCN1-4), which confer distinct biophysical properties on the channel. Despite understanding the structure-function relationships of HCN channels with different subunit stoichiometry, our knowledge of their expression in defined neuronal populations remains limited. Recently, we have shown that HCN subunit expression is a feature of a specific population of dorsal horn interneurons that exhibit high-frequency AP discharge. Here we expand on this observation and use neuroanatomical markers to first identify well-characterised neuronal populations in the lumbar spinal cord and hippocampus and subsequently determine whether HCN4 expression correlates with high-frequency AP discharge in these populations. In the spinal cord, HCN4 is expressed in several putative inhibitory interneuron populations including parvalbumin (PV)-expressing islet cells (84.1%; SD: ±2.87), in addition to all putative Renshaw cells and Ia inhibitory interneurons. Similarly, virtually all PV-expressing cells in the hippocampal CA1 subfield (93.5%; ±3.40) and the dentate gyrus (90.9%; ±6.38) also express HCN4. This HCN4 expression profile in inhibitory interneurons mirrors both the prevalence of Ih sub-threshold currents and high-frequency AP discharge. Our findings indicate that HCN4 subunits are expressed in several populations of spinal and hippocampal interneurons, which are known to express both Ih sub-threshold currents and exhibit high-frequency AP discharge. As HCN channel function plays a critical role in pain perception, learning and memory, and sleep as well as the pathogenesis of several neurological diseases, these findings provide important insights into the identity and neurochemical status of cells that could underlie such conditions. © 2013 IBRO.
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2013 |
Flynn JR, Dunn LR, Galea MP, Callister R, Callister RJ, Rank MM, 'Exercise Training after Spinal Cord Injury Selectively Alters Synaptic Properties in Neurons in Adult Mouse Spinal Cord', JOURNAL OF NEUROTRAUMA, 30 891-896 (2013) [C1]
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2012 |
Tadros MA, Harris B, Anderson WB, Brichta AM, Graham BA, Callister RJ, 'Are all spinal segments equal: Intrinsic membrane properties of superficial dorsal horn neurons in the developing and mature mouse spinal cord', Journal of Physiology, 590 2409-2425 (2012) [C1]
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2012 |
Hughes DI, Sikander S, Kinnon CM, Boyle KA, Watanabe M, Callister RJ, Graham BA, 'Morphological, neurochemical and electrophysiological features of parvalbumin-expressing cells: A likely source of axo-axonic inputs in the mouse spinal dorsal horn', Journal of Physiology, 590 3927-3951 (2012) [C1]
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2012 |
Battistuzzo CR, Callister RJ, Callister R, Galea MP, 'A systematic review of exercise training to promote locomotor recovery in animal models of spinal cord injury', Journal of Neurotrauma, 29 1600-1613 (2012) [C1]
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2012 |
De Oliveira R, Gravina FS, Lim R, Brichta AM, Callister RJ, Van Helden DF, 'Heterogeneous responses to antioxidants in noradrenergic neurons of the Locus coeruleus indicate differing susceptibility to free radical content', Oxidative Medicine and Cellular Longevity, 2012 820285 (2012) [C1]
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2011 |
De Oliveira R, Gravina FS, Lim R, Brichta AM, Callister RJ, Van Helden DF, 'Developmental changes in pacemaker currents in mouse locus coeruleus neurons', Brain Research, 1425 27-36 (2011) [C1]
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2011 |
Lim R, McPherson AE, Donne SW, Callister RJ, Brichta AM, 'Potassium accumulation between type I hair cells and calyx terminals in mouse crista', Experimental Brain Research, 210 607-621 (2011) [C1]
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2011 |
Graham BA, Tadros MA, Schofield PR, Callister RJ, 'Probing glycine receptor stoichiometry in superficial dorsal horn neurones using the spasmodic mouse', Journal of Physiology, 589 2459-2474 (2011) [C1]
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2011 |
Flynn JR, Graham BA, Galea MP, Callister RJ, 'The role of propriospinal interneurons in recovery from spinal cord injury', Neuropharmacology, 60 809-822 (2011) [C1]
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2011 |
Pringle KG, Tadros MA, Callister RJ, Lumbers ER, 'The expression and localization of the human placental prorenin/renin-angiotensin system throughout pregnancy: Roles in trophoblast invasion and angiogenesis?', Placenta, 32 956-962 (2011) [C1]
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2011 |
Flynn JR, Brichta AM, Galea MP, Callister RJ, Graham BA, 'A horizontal slice preparation for examining the functional connectivity of dorsal column fibres in mouse spinal cord', Journal of Neuroscience Methods, 200 113-120 (2011) [C1]
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2010 |
Callister RJ, Graham BA, 'Early history of glycine receptor biology in mammalian spinal cord circuits', Frontiers in Molecular Neuroscience, 3 1-13 (2010) [C1]
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2010 |
Jobling P, Graham BA, Brichta AM, Callister RJ, 'Cervix stimulation evokes predominantly subthreshold synaptic responses in mouse thoracolumbar and lumbosacral superficial dorsal horn neurons', Journal of Sexual Medicine, 7 2068-2076 (2010) [C1]
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2010 |
Lim R, Callister RJ, Brichta AM, 'An increase in glycinergic quantal amplitude and frequency during early vestibular compensation in mouse', Journal of Neurophysiology, 103 16-24 (2010) [C1]
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2010 |
De Oliveira R, Graham BA, Howlett MC, Gravina FS, Oliveira MW, Imtiaz MS, et al., 'Ketamine anesthesia helps preserve neuronal viability', Journal of Neuroscience Methods, 189 230-232 (2010) [C1]
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2010 |
Camp AJ, Lim R, Anderson WB, Schofield PR, Callister RJ, Brichta AM, 'Attenuated glycine receptor function reduces excitability of mouse medial vestibular nucleus neurons', Neuroscience, 170 348-360 (2010) [C1]
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2010 |
De Oliveira R, Howlett MC, Gravina FS, Imtiaz MS, Callister RJ, Brichta AM, Van Helden DF, 'Pacemaker currents in mouse locus coeruleus neurons', Neuroscience, 170 166-177 (2010) [C1]
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2009 |
Anderson WB, Graham BA, Beveridge NJ, Tooney PA, Brichta AM, Callister RJ, 'Different forms of glycine- and GABA(A)-receptor mediated inhibitory synaptic transmission in mouse superficial and deep dorsal horn neurons', Molecular Pain, 5 1-16 (2009) [C1]
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2009 |
Tadros MA, Graham BA, Brichta AM, Callister RJ, 'Evidence for a critical period in the development of excitability and potassium currents in mouse lumbar superficial dorsal horn neurons', Journal of Neurophysiology, 101 1800-1812 (2009) [C1]
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2008 |
Graham BA, Brichta AM, Callister RJ, 'Recording temperature affects the excitability of mouse superficial dorsal horn neurons, in vitro', Journal of Neurophysiology, 99 2048-2059 (2008) [C1]
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2007 |
Graham BA, Brichta AM, Callister RJ, 'Moving from an averaged to specific view of spinal cord pain processing circuits', Journal of Neurophysiology, 98 1057-1063 (2007) [C1]
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2007 |
Graham BA, Brichta AM, Callister RJ, 'Pinch-current injection defines two discharge profiles in mouse superficial dorsal horn neurones, in vitro', Journal of Physiology, 578 787-798 (2007) [C1]
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2007 |
Graham BA, Brichta AM, Schofield PR, Callister RJ, 'Altered potassium channel function in the superficial dorsal horn of the spastic mouse', Journal of Physiology, 584 121-136 (2007) [C1]
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2006 |
Graham BA, Schofield PR, Sah P, Margrie TW, Callister RJ, 'Distinct physiological mechanisms underlie altered glycinergic synaptic transmission in the murine mutants, spastic, spasmodic, and oscillator', Journal of Neuroscience, 26 4880-4890 (2006) [C1]
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2006 |
Lynch JW, Callister RJ, 'Glycine receptors: A new therapeutic target in pain pathways', Current Opinion in Investigational Drugs, 7 48-53 (2006) [C1]
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2006 |
Camp AJ, Callister RJ, Brichta AM, 'Inhibitory synaptic transmission differs in mouse type A and B medial vestibular nucleus neurons in vitro', Journal of Neurophysiology, 95 3208-3218 (2006) [C1]
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2005 |
Lee HY, Camp AJ, Callister RJ, Brichta AM, 'Vestibular primary afferent activity in an in vitro preparation of the mouse inner ear', Journal of Neuroscience Methods, 145 73-87 (2005) [C1]
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2005 |
Callister RJ, Pierce PA, McDonagh JC, Stuart DG, 'Slow-tonic muscle fibers and their potential innervation in the turtle, Pseudemys (Trachemys) scripta elegans', Journal of Morphology, 264 62-74 (2005) [C1]
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2004 |
Graham BA, Brichta AM, Callister RJ, 'In vivo responses of mouse superficial dorsal horn neurones to both current injection and peripheral cutaneous stimulation', Journal of Physiology, 561.3 749-763 (2004) [C1]
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2004 |
Callister RJ, Sesodia S, Enoka RM, Nemeth PM, Reinking RM, Stuart DG, 'Fatigue of Rat Hindlimb Motor Units: Biochemical -Physiological Associations', Muscle Nerve, 30 714-726 (2004) [C1]
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2004 |
Graham BA, Brichta AM, Callister RJ, 'An in vivo mouse spinal cord preparation for patch-clamp analysis of nociceptive processing', Journal of Neuroscience Methods, 136 221-228 (2004) [C1]
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2004 |
McDonagh J, Callister RJ, Favron M, Stuart D, 'Resistance to disuse atrophy in a turtle hindlimb muscle', Journal of Comparative Physiology A-Neuroethology Sensory Neural and Behavioural Physiology, 190(4) 321-329 (2004) [C1]
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2003 |
Graham BA, Schofield PR, Sah P, Callister RJ, 'Altered inhibitory synaptic transmission in superficial dorsal horn neurones in spastic and oscillator mice', The Journal of Physiology, 551.3 905-916 (2003) [C1]
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2003 |
Callister RJ, Reinking RM, Stuart DG, 'Effects of fatigue on the catchlike property in a turtle hindlimb muscle', Journal of Comparative Physiology A, 189 857-866 (2003) [C1]
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2002 |
Camp AJ, Lee H, Callister RJ, Brichta AM, 'Afferent responses to mechanical stimulation and drug application in mouse in-vitro labyrinth', Journal of Vestibular Research, 11 175 (2002) [C3]
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2002 |
Brichta AM, Camp AJ, Lee H, Callister RJ, 'Intra-axonal recordings from canal afferents in the mouse in-vitro labyrinth', Journal of Vestibular Research, 11 177-178 (2002) [C3]
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2002 |
Graham BA, Schofield P, Sah P, Callister RJ, 'GABAAergic and glycinergic synaptic transmission in superficial dorsal horn neurones of wild type, spastic and oscillator mice', Proceedings of the Australian Neuroscience Society, 22:94 n/a (2002) [C3]
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2001 |
Faber ESL, Callister RJ, Sah P, 'Morphological and Electrophysiological Properties of Principal Neurons in the Rat Lateral Amygdala In Vitro', Journal of Neurophysiology, 85 714-723 (2001) [C1]
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1999 |
Callister RJ, Schofield P, Sah P, 'The use of murine mutants to study glycine receptor function', Clinical and Experimental Pharmacology and Physiology., 26 929-931 (1999) [C1]
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1999 |
Callister RJ, Peterson E, Brichta AM, 'Neuromuscular strategies underlying ballistic movements', Progress in Brain Research, 123 233-243 (1999) [C1]
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Show 91 more journal articles |
Conference (72 outputs)
Year | Citation | Altmetrics | Link | ||||||||
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2017 |
Marks E, Naudin C, Walker MM, Veysey M, Foster P, Talley NJ, et al., 'REGULATION OF IL-12P40 BY HIF CONTROLS TH1/TH17 RESPONSES TO PREVENT MUCOSAL INFLAMMATION', GASTROENTEROLOGY, Chicago, IL (2017)
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2015 |
Farrell K, Rank M, Keely S, Graham B, Callister R, 'In vivo electrophysiological characterisation of mouse lumbosacral dorsal horn neurons receiving visceral inputs', JOURNAL OF NEUROCHEMISTRY, Cairns, AUSTRALIA (2015) [E3]
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2015 |
Smith K, Dickinson S, Jobling P, Callister R, Graham B, 'Peripheral nerve injury alters the excitability of calretinin positive dorsal horn neurons', JOURNAL OF NEUROCHEMISTRY, Cairns, AUSTRALIA (2015) [E3]
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2015 |
Tadros M, Lim R, Hughes D, Jobling P, Brichta A, Callister R, 'Electrical maturation of sensorimotor processing in the human foetus', JOURNAL OF NEUROCHEMISTRY, Cairns, AUSTRALIA (2015) [E3]
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2015 |
Rank M, Flynn J, Galea M, Callister R, Callister R, 'The spinal cord that changes itself: spontaneous recovery of interneurons after incomplete spinal cord injury', JOURNAL OF NEUROCHEMISTRY, Cairns, AUSTRALIA (2015) [E3]
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2015 |
Gradwell M, Callister R, Hughes D, Graham B, 'Optogenetic dissection of a parvalbumin interneuron microcircuits within the superficial dorsal horn of the spinal cord', JOURNAL OF NEUROCHEMISTRY, Cairns, AUSTRALIA (2015) [E3]
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2014 |
Lim R, Drury HR, Camp AJ, Tadros MA, Callister RJ, Brichta AM, 'Anatomical and physiological characterisation of human vestibular hair cells', Journal of Vestibular Research: Equilibrium and Orientation: an international journal of experimental and clinical vestibular science, Buenos Aires, Argentina (2014) [E3]
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2014 |
Farrell KE, Graham BA, Keely S, Callister RJ, 'Understanding the mechanisms underlying chronic pain in IBD: A new method for studying visceral inputs from the gastrointestinal tract', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2014) [E3]
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2014 |
Wellings TP, Graham BA, Camp AJ, Callister RJ, Brichta AM, Lim R, 'Calcium binding proteins subdivide medial vestibular nucleus neurons', Journal of Vestibular Research: Equilibrium and Orientation: an international journal of experimental and clinical vestibular science, Buenos Aires, Argentina (2014) [E3]
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2014 |
Poppi LA, Tabatabaee H, Callister RJ, Lim R, Brichta AM, 'Cholinergic Activity of the Peripheral Efferent Vestibular System', Journal of Vestibular Research: Equilibrium and Orientation: an international journal of experimental and clinical vestibular science, Buenos Aires, Argentina (2014) [E3]
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2013 |
Poppi LA, Tabatabaee H, Callister RJ, Lim R, Brichta AM, 'From the ear to the brain, and back again the Efferent Vestibular System', 4th UWS Sensory Neuroscience Symposium, Sydney (2013) [E3]
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2013 |
Poppi LA, Tabatabaee H, Callister RJ, Lim R, Brichta AM, 'Efferent Vestibular System the mysterious part of the periphery', Neuro-Otology Society of Australia, Melbourne (2013) [E3]
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2013 |
Tadros MA, Fuglevand AJ, Brichta AM, Callister RJ, 'Electrophysiological properties of cranial and spinal motor neurons in mice', Proceedings of the Australian Neuroscience Society, Melbourne (2013) [E3]
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2012 |
Zouikr I, Tadros MA, Callister RJ, Nakamura T, Beagley K, Clifton V, Hodgson DM, 'Neonatal lipopolysaccharide exposure alters nociception', Abstracts of the 21st Annual Meeting of the International Behavioral Neuroscience Society, Kona, Hawaii (2012) [E3]
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2012 |
Fiore CB, Hickey LE, Rank MM, Callister R, Callister RJ, Galea MP, 'Duration of treadmill training and recovery of locomotion in spinal cord injured mice', Abstracts. Australian Neuroscience Society 32nd Annual Meeting, Gold Coast, Queensland (2012) [E3]
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2012 |
Rank MM, Flynn JR, Fiore CB, Hickey LE, Galea MP, Callister R, Callister RJ, 'Effect of treadmill exercise on intrinsic and synaptic properties of spinal neurons following spinal cord injury in adult mice', Abstracts. Australian Neuroscience Society 32nd Annual Meeting, Gold Coast, Queensland (2012) [E3]
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2012 |
Flynn JR, Callister RJ, Graham BA, 'Electrophysiological properties of identified long descending propriospinal neurons in mice', Abstracts. Australian Neuroscience Society 32nd Annual Meeting, Gold Coast, Queensland (2012) [E3]
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2012 |
Tadros MA, Lim R, Graham BA, Hughes DI, Brichta AM, Callister RJ, 'Excitability of human ventral horn neurons during early foetal development', Abstracts. Australian Neuroscience Society 32nd Annual Meeting, Gold Coast, Queensland (2012) [E3]
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2012 |
Zouikr I, Tadros MA, Callister RJ, Nakamura T, Beagley K, Hodgson DM, 'Long-term impact of neonatal exposure to a bacterial mimetic on nociception', Abstracts. Australian Neuroscience Society 32nd Annual Meeting, Gold Coast, Queensland (2012) [E3]
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2012 |
Callister R, Fiore CB, Callister RJ, Galea MP, 'A systematic review of locomotor training as a therapy in animal models of spinal cord injury', Abstracts. Australian Neuroscience Society 32nd Annual Meeting, Gold Coast, Queensland (2012) [E3]
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2012 |
Lim R, Camp AJ, Tadros MA, Drury HR, Callister RJ, Brichta AM, 'Whole cell conductances of developing human hair cells', Abstracts. Australian Neuroscience Society 32nd Annual Meeting, Gold Coast, Queensland (2012) [E3]
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2012 |
Lim R, Callister RJ, Brichta AM, 'The other part of the ear - a 'balanced' view', Sydney 2012 Joint AuPS/PSNZ/ASB Meeting. Programme, Sydney, NSW (2012) [E3]
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2012 |
Farrell KE, Keely S, Graham BA, Minahan KL, Madden JF, Callister RJ, 'Spinal cord signalling in a mouse model of inflammatory bowel disease', Journal of Gastroenterology and Hepatology, Adelaide, SA (2012) [E3]
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2011 |
Burrows TL, Collins CE, Truby H, Callister RJ, Morgan PJ, Davies PSW, 'Doubly labelled water validation of child versus parent report of total energy intake by food frequency questionnaire', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
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2011 |
Tadros MA, Lim R, Graham BA, Hughes DI, Brichta AM, Callister RJ, 'Excitability of human ventral horn neurons during early foetal development', Poster Abstracts. Australian Neuroscience Society Annual Meeting, Auckland, NZ (2011) [E3]
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2011 |
Graham BA, Sah P, Brichta AM, Callister RJ, Hughes DI, 'Neuroanatomical and neurochemical features of parvalbumin-expressing neurons in the mouse spinal dorsal horn', Posters. Australian Neuroscience Society 31st Annual Meeting, Auckland, New Zealand (2011) [E3]
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2010 |
Lim R, Camp AJ, Walsh M, Callister RJ, Brichta AM, 'In-vitro whole-cell conductances recorded from developing human cristae', Journal of Vestibular Research, Reykavik, Iceland (2010) [E3]
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2010 |
Lim R, Stitt I, Camp AJ, Callister RJ, Brichta AM, 'Inhibitory synaptic transmission in the lateral vestibular nucleus', Journal of Vestibular Research, Reykavik, Iceland (2010) [E3]
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2010 |
Callister RJ, Walsh MA, Harris BM, Anderson WB, Brichta AM, Graham BA, 'Segmental and developmental differences in the excitability of mouse superficial dorsal horn neurons', 13th World Congress on Pain: Abstracts, Montreal, QC (2010) [E3]
|
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2010 |
Walsh MA, Farrell KE, Graham BA, Brichta AM, Callister RJ, 'Sodium current properties differ in neonate and adult superficial dorsal horn neurons', 13th World Congress on Pain: Abstracts, Montreal, QC (2010) [E3]
|
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2010 |
Harris BM, Graham BA, Bolton PS, Brichta AM, Callister RJ, 'Influence of acute neck muscle inflammation on the excitability of superficial dorsal horn neurons', 13th World Congress on Pain: Abstracts, Montreal, QC (2010) [E3]
|
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2010 |
Hughes DI, Sah P, Callister RJ, Graham BA, 'Neuroanatomical and electrophysiological features of parvalbumin-expressing neurons in the rodent spinal dorsal horn', 13th World Congress on Pain: Abstracts, Montreal, QC (2010) [E3]
|
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2010 |
Graham BA, Hughes DI, Lim R, Sah P, Brichta AM, Callister RJ, 'Characterization of calretinin expressing interneurons in the superficial dorsal horn of the mouse spinal cord', 13th World Congress on Pain: Abstracts, Montreal, QC (2010) [E3]
|
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2009 |
De Oliveira R, Howlett MC, Gravina FS, Imtiaz MS, Callister RJ, Brichta AM, Van Helden DF, 'Ion channel modulation by reactive species in mice locus coeruleus neurons', Journal of Physiological Sciences, Kyoto, Japan (2009) [E3]
|
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2009 |
Hutchesson MJ, Collins CE, Callister RJ, Morgan PJ, 'Validity of self-reported energy intake from a web-based food diary before and after a web-based weight loss program', 7th International Conference on Diet and Activity Methods (ICDAM7): Program and Abstracts, Washington, DC (2009) [E3]
|
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2009 |
Graham BA, Schofield PR, Callister RJ, 'Glycine receptor mediated synaptic transmission in the superficial dorsal horn of Spasmodic mice', ANS 2009 Abstracts: Posters, Canberra, ACT (2009) [E3]
|
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2009 |
Lim R, Schofield PR, Callister RJ, 'Altered inhibitory synaptic transmission in spastic and spastic-rescue mice', ANS 2009 Abstracts: Posters, Canberra, ACT (2009) [E3]
|
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2009 |
Tadros MA, Anderson WB, Graham BA, Callister RJ, 'Responses to current injection differ between mouse cervical, thoracic and lumbar superficial dorsal horn neurons', ANS 2009 Abstracts: Posters, Canberra, ACT (2009) [E3]
|
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2009 |
De Oliveira R, Howlett MC, Gravina FS, Imtiaz MS, Callister RJ, Brichta AM, Van Helden DF, 'Effect of antioxidants in pacemaking of mice locus coeruleus neurons', ANS 2009 Abstracts: Posters, Canberra, ACT (2009) [E3]
|
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2009 |
Brichta AM, Lamont E, Lim R, Callister RJ, 'Vestibular effects of endolymphatic ionic and volume changes in an isolated preparation of a mouse labyrinth', Abstracts of the Thirty-Second Annual Midwinter Research Meeting Association for Research in Otolaryngology, Baltimore, MD (2009) [E3]
|
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2009 |
McPherson AE, Lim R, Callister RJ, Brichta AM, 'Voltage dependent currents in Type I and II hair cells and calyx terminals of primary afferents in an intact in vitro mouse vestibular crista preparation', Abstracts of the Thirty-Second Annual Midwinter Research Meeting Association for Research in Otolaryngology, Baltimore, MD (2009) [E3]
|
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2009 |
Lim R, Callister RJ, Brichta AM, 'Changes in glycinergic synaptic transmission and neuronal excitability in mouse medial vestibular nucleus neurons during early vestibular compensation', Abstracts of the Thirty-Second Annual Midwinter Research Meeting Association for Research in Otolaryngology, Baltimore, MD (2009) [E3]
|
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2009 |
Lim R, McPherson AE, Pow DV, Callister RJ, Brichta AM, 'Glutamate transport in the mouse inner ear is mediated by the excitatory amino acid transporter, EAAT5', Abstracts of the Thirty-Second Annual Midwinter Research Meeting Association for Research in Otolaryngology, Baltimore, MD (2009) [E3]
|
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2008 |
Anderson WB, Graham BA, Jobling P, Brichta AM, Callister RJ, 'Inhibitory synaptic transmission and cannabinoid effects differ in mouse superficial and deep dorsal horn neurons', Proceedings of the Australian Neuroscience Society, Hobart, TAS (2008) [E3]
|
||||||||||
2008 |
Jobling P, Graham BA, Brichta AM, Callister RJ, 'In vivo patch clamp recording of synaptic events evoked in superficial dorsal horn neurons after stimulation of the female reproductive tract in the mouse', Proceedings of the Australian Neuroscience Society, Hobart, TAS (2008) [E3]
|
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2008 |
De Oliveira R, Howlett MC, Gravina FS, Imtiaz MS, Callister RJ, Brichta AM, Van Helden DF, 'Influence of mitochondria in the interspike interval pacemaking currents of mice Locus Coeruleus neurons', Proceedings of the Australian Physiological Society, Melbourne, VIC (2008) [E3]
|
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2008 |
Callister RJ, Brichta AM, Graham BA, 'Beyond the dorsal horn: The use of animal models to discover new sites for pain therapy', Australian and New Zealand Journal of Psychiatry, Newcastle, NSW (2008) [E3]
|
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2008 |
Ansell WH, Rivett DA, Callister RJ, 'Overuse injuries and patterns of stretching in Ironman triathletes', Australian Journal of Physiotherapy: eSupplements, Cairns, QLD (2008) [E3]
|
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2007 |
Camp AJ, Anderson WB, Callister RJ, Schofield PR, Brichta AM, 'Contribution of inhibitory synaptic transmission to the intrinsic membrane properties of Medial Vestibular Nucleus (MVN) neurons (Poster)', 7th IBRO 2007 World Congress of Neuroscience Program, Melbourne (2007) [E3]
|
||||||||||
2006 |
Anderson WB, Graham BA, Jobling P, Lim R, Brichta AM, Callister RJ, 'Glycine receptor diversity in the dorsal horn of the mouse spinal cord', Society for Neuroscience, Atlanta, GA (2006) [E3]
|
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2006 |
Jobling P, Graham BA, Brichta AM, Callister RJ, 'In vivo patch-clamp recording of subthreshold synaptic events evoked in dorsal horn neurons after stimulation of the female reproductive tract in the mouse', Society for Neuroscience, Atlanta, Georgia (2006) [E3]
|
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2006 |
Walsh MA, Graham BA, Brichta AM, Callister RJ, 'Postnatal development of electrophysiological properties in mouse supeficial dorsal horn neurones', Proceedings of the Australian Neuroscience Society, Sydney (2006) [E3]
|
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2005 |
Graham BA, Brichta AM, Callister RJ, 'Effect of Temperature on the Discharge Properties of Mouse Superficial Dorsal Horn Neurons', Proceedings of the Australian Neuroscience Society, Perth (2005) [E3]
|
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2005 |
Camp AJ, Watson PJ, Schofield PR, Callister RJ, Brichta AM, 'Inhibitory Synaptic Transmission in Medial Vestibular Nucleus Neurons of Wildtype, Spastic, Spasmodic, and Oscillator Mice', Proceedings of the Australian Neuroscience Society, Perth (2005) [E3]
|
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2005 |
Callister RJ, Graham BA, Brichta AM, 'In Vivo Responses of Mouse Spinal Neurones to Electrical and Functionally-Relevant Stimulation', Proceedings of the Australian Neuroscience Society Conference, Perth (2005) [E3]
|
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2004 |
Krajniak SG, Callister RJ, Imtiaz MS, Brichta AM, Van Helden DF, 'Investigation of a brain rhythm', Proceedings of the Australian Neuroscience Society, Australia (2004) [E3]
|
||||||||||
2001 |
Lee H-Y, Callister RJ, Brichta AM, 'Morphophysiology of Vestibular Afferents Recorded from an In Vitro Preparation of the Mouse Inner Ear', Abstracts of the Twenty-Fourth Annual Midwinter Research Meeting of the Association for Research in Otolaryngology, U.S.A. (2001) [C3]
|
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2001 |
Lee H-Y, Callister RJ, Brichta AM, 'Physiology of Labelled Vestibular Afferents Recorded from an In Vitro Preparation of the Mouse Inner Ear', Proceedings of the Australian Neuroscience Society, Australia (2001) [C3]
|
||||||||||
2001 | O'Callaghan AE, Schofield PR, Sah P, Callister RJ, 'Development of GABAa-ergic Synaptic Connections in the Spastic Mouse', Proceedings of the Australian Neuroscience Society, Australia (2001) [C3] | ||||||||||
2001 | Morgan BS, Morris R, Callister RJ, Schofield PR, 'Molecular Changes to Glycine Receptors by Gene Therapy and Transgenic Apporaches for the Study of Synaptic Neurotransmission', Journal of Neurochemistry, U.K. (2001) [C3] | ||||||||||
2001 | O'Callaghan AE, Ryan HR, Schofield PR, Sah P, Callister RJ, 'Developmental Changes in Inhibitory Synaptic Transmission in Brainstem Motoneurons, in the Spastic Mouse', Society for Neuroscience Program, 31st Annual Meeting, San Diego, California, November 10-15, 2001., U.S.A. (2001) [C3] | ||||||||||
1999 | Margrie TW, Callister RJ, Schofield P, Sah P, 'Altered Glycinergic and GABAergic synaptic transmission in the murine mutant, spastic', Proceedings of the Australian Neuroscience Society. Vol. 10, University of Tasmania, Hobart, Tasmania. (1999) [E1] | ||||||||||
1999 | Morgan B, Callister RJ, Handford C, Walker S, Sah P, Schofield P, 'Molecular studies of synaptic neurotransmission: development of transgenic animal models', Proceedings of the Australian Neuroscience Society. Vol. 10, University of Tasmania, Hobart, Tasmania. (1999) [E1] | ||||||||||
1999 | Ryan H, Margrie TW, Schofield P, Sah P, Callister RJ, 'Compensatory Increases in GABAergic Synaptic Transmission in the Murine Mutant, Spastic', Proceedings of the Australian Physiological and Pharmacological Society. Vol. 30, No. 2., The University of Newcastle, Newcastle, N.S.W. (1999) [E2] | ||||||||||
Show 69 more conferences |
Grants and Funding
Summary
Number of grants | 74 |
---|---|
Total funding | $7,624,644 |
Click on a grant title below to expand the full details for that specific grant.
20181 grants / $665,718
Excitatory interneurons: a sensory amplifier for pathological pain $665,718
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Associate Professor Brett Graham, Conjoint Professor Robert Callister, Dr David Hughes, Professor Chris Dayas |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2018 |
Funding Finish | 2020 |
GNo | G1700334 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
20171 grants / $70,000
UON 2017 Researcher Equipment Grant $70,000
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Researcher Equipment Grants |
Role | Lead |
Funding Start | 2017 |
Funding Finish | 2017 |
GNo | G1701165 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
20161 grants / $510,121
Mechanisms underlying efferent feedback in the vestibular system$510,121
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Professor Alan Brichta, Associate Professor Brett Graham, Doctor Rebecca Lim, Conjoint Professor Robert Callister, Dr Chris Holt, Professor Chris Dayas, Professor Richard Rabbitt |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2016 |
Funding Finish | 2019 |
GNo | G1500239 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
20153 grants / $111,348
High throughput automated all-in-one laser scanning FLUOVIEW FV10i microscope$54,698
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Professor Xu Dong Zhang, Conjoint Professor Robert Callister, Laureate Professor John Aitken, Associate Professor Pradeep Tanwar, Doctor Chen Chen Jiang, Doctor Lei Jin |
Scheme | Equipment Grant |
Role | Investigator |
Funding Start | 2015 |
Funding Finish | 2015 |
GNo | G1501576 |
Type Of Funding | Other Public Sector - Commonwealth |
Category | 2OPC |
UON | Y |
Development of a laboratory model to study adult motoneurons$36,650
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
---|---|
Project Team | Doctor Melissa Tadros, Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2015 |
Funding Finish | 2015 |
GNo | G1501432 |
Type Of Funding | C3120 - Aust Philanthropy |
Category | 3120 |
UON | Y |
Dizzy and Deaf - restoring signals from the inner ear$20,000
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
---|---|
Project Team | Doctor Rebecca Lim, Professor Alan Brichta, Conjoint Professor Robert Callister, Associate Professor Doug Smith |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2015 |
Funding Finish | 2015 |
GNo | G1501395 |
Type Of Funding | Grant - Aust Non Government |
Category | 3AFG |
UON | Y |
20142 grants / $556,477
Spinal processing of sensory signals from the gut$554,477
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Conjoint Professor Robert Callister, Associate Professor Simon Keely, Associate Professor Brett Graham, Professor Alan Brichta, Dr David Hughes |
Scheme | Project Grant |
Role | Lead |
Funding Start | 2014 |
Funding Finish | 2017 |
GNo | G1300361 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
Society for Neuroscience Annual Meeting, Washington USA, 15 - 19 November 2014.$2,000
Funding body: University of Newcastle - Faculty of Health and Medicine
Funding body | University of Newcastle - Faculty of Health and Medicine |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Travel Grant |
Role | Lead |
Funding Start | 2014 |
Funding Finish | 2014 |
GNo | G1400799 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
20135 grants / $964,075
The role of presynaptic inhibition in neuropathic pain$482,705
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Associate Professor Brett Graham, Conjoint Professor Robert Callister, Dr David Hughes, Professor George Augustine |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2013 |
Funding Finish | 2015 |
GNo | G1200088 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
Development of functional connections in the human peripheral vestibular system$438,370
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Doctor Rebecca Lim, Professor Alan Brichta, Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2013 |
Funding Finish | 2017 |
GNo | G1200254 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
Leica TP 1020 Automatic Tissue Processor for histology applications$35,000
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Associate Professor Pradeep Tanwar, Professor Eileen McLaughlin, Professor Xu Dong Zhang, Conjoint Professor Robert Callister, Associate Professor Phillip Dickson, Professor Hubert Hondermarck, Doctor Jean-Marie Sontag, Professor Dirk Van Helden, Associate Professor Doug Smith, Associate Professor Phil Jobling, Associate Professor Estelle Sontag, Associate Professor Paul Tooney, Associate Professor Susan Hua, Doctor Janet Bristow, Associate Professor Jay Horvat, Professor Liz Milward, Professor Adam McCluskey, Professor Brett Nixon, Doctor Rebecca Lim, Professor Alan Brichta |
Scheme | Equipment Grant |
Role | Investigator |
Funding Start | 2013 |
Funding Finish | 2013 |
GNo | G1201185 |
Type Of Funding | Other Public Sector - Commonwealth |
Category | 2OPC |
UON | Y |
2014 ARC/NHMRC Fellowship External Applicant Support - FHM$6,000
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister, Dr Nathan Bartlett |
Scheme | Special Project Grant |
Role | Lead |
Funding Start | 2013 |
Funding Finish | 2013 |
GNo | G1301137 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Society for Neuroscience Annual Meeting, San Diego, California, 9 - 13 November 2013$2,000
Funding body: University of Newcastle - Faculty of Health and Medicine
Funding body | University of Newcastle - Faculty of Health and Medicine |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Travel Grant |
Role | Lead |
Funding Start | 2013 |
Funding Finish | 2013 |
GNo | G1300866 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
20123 grants / $482,004
Development of peripheral sensory pathways in humans$477,504
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Conjoint Professor Robert Callister, Professor Alan Brichta, Dr David Hughes, Associate Professor Phil Jobling |
Scheme | Project Grant |
Role | Lead |
Funding Start | 2012 |
Funding Finish | 2014 |
GNo | G1100102 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
Young pain researcher support$2,500
Funding body: Hunter Pain Clinic
Funding body | Hunter Pain Clinic |
---|---|
Project Team | Conjoint Professor Robert Callister, Dr Melissa Walsh |
Scheme | Research Grant |
Role | Lead |
Funding Start | 2012 |
Funding Finish | 2012 |
GNo | G1200779 |
Type Of Funding | Grant - Aust Non Government |
Category | 3AFG |
UON | Y |
Society for neuroscience annual meeting, New Orleans, 13 - 17 October 2012$2,000
Funding body: University of Newcastle - Faculty of Health and Medicine
Funding body | University of Newcastle - Faculty of Health and Medicine |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Travel Grant |
Role | Lead |
Funding Start | 2012 |
Funding Finish | 2013 |
GNo | G1200660 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
20111 grants / $339,208
Efferent modulation of the vestibular periphery$339,208
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Professor Alan Brichta, Conjoint Professor Robert Callister, Doctor Rebecca Lim |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2011 |
Funding Finish | 2013 |
GNo | G1000315 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
20107 grants / $1,112,242
Connectivity of regenerating axons following spinal cord injury$385,125
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Professor Mary Galea, Conjoint Professor Robert Callister, Conjoint Professor Robin Callister |
Scheme | Project Grant |
Role | Lead |
Funding Start | 2010 |
Funding Finish | 2012 |
GNo | G1000065 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
Laser microdissection microscopy system for cell and development biology$350,000
Funding body: ARC (Australian Research Council)
Funding body | ARC (Australian Research Council) |
---|---|
Project Team | Professor Eileen McLaughlin, Conjoint Professor Keith Jones, Laureate Professor John Aitken, Professor Brett Nixon, Doctor Shaun Roman, Professor Alan Brichta, Doctor Rick Thorne, Associate Professor Doug Smith, Associate Professor David McCurdy, Emeritus Professor Ray Rose, Professor Christopher Grof, Emeritus Professor Leonie Ashman, Professor Gordon Burns, Associate Professor Brett Graham, Associate Professor Paul Tooney, Laureate Professor Roger Smith, Laureate Professor Paul Foster, Professor Trevor Day, Conjoint Professor Robert Callister |
Scheme | Linkage Infrastructure Equipment & Facilities (LIEF) |
Role | Investigator |
Funding Start | 2010 |
Funding Finish | 2010 |
GNo | G0190369 |
Type Of Funding | Scheme excluded from IGS |
Category | EXCL |
UON | Y |
Laser microdissection microscopy system for cell and development biology$215,000
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Professor Eileen McLaughlin, Conjoint Professor Keith Jones, Laureate Professor John Aitken, Professor Brett Nixon, Doctor Shaun Roman, Professor Alan Brichta, Doctor Rick Thorne, Associate Professor Doug Smith, Associate Professor David McCurdy, Emeritus Professor Ray Rose, Professor Christopher Grof, Emeritus Professor Leonie Ashman, Professor Gordon Burns, Associate Professor Brett Graham, Associate Professor Paul Tooney, Laureate Professor Roger Smith, Laureate Professor Paul Foster, Professor Trevor Day, Conjoint Professor Robert Callister |
Scheme | Equipment Grant |
Role | Investigator |
Funding Start | 2010 |
Funding Finish | 2010 |
GNo | G1000874 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
HMRI MRSP Infrastructure Grant (10-11) - Cardiovascular$76,117
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
---|---|
Project Team | Professor Derek Laver, Professor Dirk Van Helden, Associate Professor Eugene Nalivaiko, Professor Liz Milward, Conjoint Professor Robert Callister, Professor Manohar Garg, Conjoint Professor Tony Quail |
Scheme | NSW MRSP Infrastructure Grant |
Role | Investigator |
Funding Start | 2010 |
Funding Finish | 2010 |
GNo | G1100525 |
Type Of Funding | Other Public Sector - State |
Category | 2OPS |
UON | Y |
Laser microdissection microscopy system for cell and development biology (HMRI contribution towards 2010 ARC LIEF grant)$50,000
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
---|---|
Project Team | Professor Eileen McLaughlin, Conjoint Professor Keith Jones, Laureate Professor John Aitken, Professor Brett Nixon, Doctor Shaun Roman, Professor Alan Brichta, Doctor Rick Thorne, Associate Professor Doug Smith, Associate Professor David McCurdy, Emeritus Professor Ray Rose, Professor Christopher Grof, Emeritus Professor Leonie Ashman, Professor Gordon Burns, Associate Professor Brett Graham, Associate Professor Paul Tooney, Laureate Professor Roger Smith, Laureate Professor Paul Foster, Professor Trevor Day, Conjoint Professor Robert Callister |
Scheme | Equipment Grant |
Role | Investigator |
Funding Start | 2010 |
Funding Finish | 2010 |
GNo | G1000144 |
Type Of Funding | Other Public Sector - State |
Category | 2OPS |
UON | Y |
ABI 7500 Real Time PCR System $34,000
Funding body: NHMRC (National Health & Medical Research Council)
13th World Congress on Pain, Montreal, Canada, 29 August - 2 September 2010$2,000
Funding body: University of Newcastle - Faculty of Health and Medicine
Funding body | University of Newcastle - Faculty of Health and Medicine |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Travel Grant |
Role | Lead |
Funding Start | 2010 |
Funding Finish | 2011 |
GNo | G1000443 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
20093 grants / $496,144
Spinal mechanisms underlying neck pain$451,500
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Conjoint Professor Robert Callister, Conjoint Professor Philip Bolton, Professor Alan Brichta |
Scheme | Project Grant |
Role | Lead |
Funding Start | 2009 |
Funding Finish | 2011 |
GNo | G0188840 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
Neurometer CPT/C$28,435
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Conjoint Professor Philip Bolton, Conjoint Professor Robert Callister, Professor Alan Brichta, Conjoint Professor Robin Callister, Associate Professor Brett Graham, Associate Professor Phil Jobling |
Scheme | Equipment Grant |
Role | Investigator |
Funding Start | 2009 |
Funding Finish | 2009 |
GNo | G0189845 |
Type Of Funding | Other Public Sector - Commonwealth |
Category | 2OPC |
UON | Y |
Leica VT1200S - Fully automated vibrating blade microtome$16,209
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Conjoint Professor Robert Callister, Professor Alan Brichta, Conjoint Professor Keith Jones, Professor Jon Hirst, Associate Professor Brett Graham, Conjoint Professor Philip Bolton, Associate Professor Phil Jobling, Associate Professor Paul Tooney, Doctor Angela McPherson, Doctor Rebecca Lim, Doctor Ramatis De Oliveira, Mr Matthew Walsh |
Scheme | Equipment Grant |
Role | Lead |
Funding Start | 2009 |
Funding Finish | 2009 |
GNo | G0189842 |
Type Of Funding | Other Public Sector - Commonwealth |
Category | 2OPC |
UON | Y |
20083 grants / $46,569
Recovery of the balance system following injury$24,069
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
---|---|
Project Team | Professor Alan Brichta, Conjoint Professor Robert Callister, Conjoint Professor Philip Bolton, Associate Professor Phil Jobling, Doctor Rebecca Lim |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2008 |
Funding Finish | 2008 |
GNo | G0188471 |
Type Of Funding | Contract - Aust Non Government |
Category | 3AFC |
UON | Y |
Leica VT2100S Vibrating Microtome$20,000
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Professor Alan Brichta, Conjoint Professor Robert Callister, Professor Dirk Van Helden, Conjoint Professor Philip Bolton, Doctor Rebecca Lim, Associate Professor Brett Graham, Dr Marcus Howlett, Doctor Angela McPherson, Doctor Mohammad Imtiaz, Doctor Ramatis De Oliveira, Mr Wayne Anderson, Mr Matthew Walsh |
Scheme | Equipment Grant |
Role | Investigator |
Funding Start | 2008 |
Funding Finish | 2008 |
GNo | G0188540 |
Type Of Funding | Other Public Sector - Commonwealth |
Category | 2OPC |
UON | Y |
12th World Congress on Pain, Glasgow Scotland, 17/8/2008 - 22/8/2008$2,500
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Travel Grant |
Role | Lead |
Funding Start | 2008 |
Funding Finish | 2008 |
GNo | G0189221 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
20074 grants / $54,430
High speed/sensitivity CCD camera$30,000
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Professor Dirk Van Helden, Professor Eileen McLaughlin, Professor Gordon Burns, Doctor Rick Thorne, Dr Marcus Howlett, Doctor Mohammad Imtiaz, Professor Alan Brichta, Conjoint Professor Robert Callister, Associate Professor Brett Graham, Professor Derek Laver, Professor Liz Milward, Associate Professor John Holdsworth |
Scheme | Equipment Grant |
Role | Investigator |
Funding Start | 2007 |
Funding Finish | 2007 |
GNo | G0188196 |
Type Of Funding | Other Public Sector - Commonwealth |
Category | 2OPC |
UON | Y |
Identifying new spinal cord targets for pain management.$14,252
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
---|---|
Project Team | Associate Professor Brett Graham, Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2007 |
Funding Finish | 2007 |
GNo | G0187234 |
Type Of Funding | Contract - Aust Non Government |
Category | 3AFC |
UON | Y |
Developing a rodent model to study neck pain$7,678
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister, Conjoint Professor Philip Bolton, Professor Alan Brichta, Associate Professor Brett Graham |
Scheme | Pilot Grant |
Role | Lead |
Funding Start | 2007 |
Funding Finish | 2007 |
GNo | G0187879 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Annual meeting of the Society for Neuroscience$2,500
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Travel Grant |
Role | Lead |
Funding Start | 2007 |
Funding Finish | 2007 |
GNo | G0188306 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
20063 grants / $1,005,402
Descending control of pain pathways$423,950
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Conjoint Professor Robert Callister, Professor Trevor Day, Professor Alan Brichta |
Scheme | Project Grant |
Role | Lead |
Funding Start | 2006 |
Funding Finish | 2008 |
GNo | G0185184 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
The neural basis of vestibular compensation$311,472
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Professor Alan Brichta, Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2006 |
Funding Finish | 2008 |
GNo | G0185195 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
Cellular mechanisms underlying activity in the peripheral vestibular organs$269,980
Funding body: The Garnett Passe and Rodney Williams Memorial Foundation
Funding body | The Garnett Passe and Rodney Williams Memorial Foundation |
---|---|
Project Team | Professor Alan Brichta, Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2006 |
Funding Finish | 2008 |
GNo | G0185817 |
Type Of Funding | Aust Competitive - Non Commonwealth |
Category | 1NS |
UON | Y |
20054 grants / $244,000
INVESTIGATION OF A BRAIN RHYTHM$220,000
Funding body: ARC (Australian Research Council)
Funding body | ARC (Australian Research Council) |
---|---|
Project Team | Professor Dirk Van Helden, Conjoint Professor Robert Callister, Professor Alan Brichta |
Scheme | Discovery Projects |
Role | Investigator |
Funding Start | 2005 |
Funding Finish | 2007 |
GNo | G0184333 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
Novel spinal cord targets for pain management$13,000
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
---|---|
Project Team | Conjoint Professor Robert Callister, Professor Alan Brichta |
Scheme | Project Grant |
Role | Lead |
Funding Start | 2005 |
Funding Finish | 2005 |
GNo | G0184884 |
Type Of Funding | Contract - Aust Non Government |
Category | 3AFC |
UON | Y |
Descending control of pain processing pathways in the spinal cord$10,000
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister, Professor Alan Brichta, Professor Trevor Day |
Scheme | Project Grant |
Role | Lead |
Funding Start | 2005 |
Funding Finish | 2005 |
GNo | G0184748 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Annual Meeting of the Society for Neuroscience, 12-16 November 2005$1,000
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Travel Grant |
Role | Lead |
Funding Start | 2005 |
Funding Finish | 2005 |
GNo | G0185934 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
20045 grants / $214,256
Molecular determinants of inhibitory synoptic function studies using mutant and transgenic mice$180,000
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Lead |
Funding Start | 2004 |
Funding Finish | 2006 |
GNo | G0183988 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
How does the balance system process signals?$14,500
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Professor Alan Brichta, Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2004 |
Funding Finish | 2004 |
GNo | G0183499 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Investigation a brain rythym$14,500
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Professor Dirk Van Helden, Conjoint Professor Robert Callister, Professor Alan Brichta |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2004 |
Funding Finish | 2004 |
GNo | G0184506 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Visit of Professor Douglas Stuart 29 March 2004 to 14 May 2004$3,426
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Visitor Grant |
Role | Lead |
Funding Start | 2004 |
Funding Finish | 2004 |
GNo | G0183869 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Annual Meeting of the Society of Neuroscience, 23-27 October 2004, USA$1,830
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Travel Grant |
Role | Lead |
Funding Start | 2004 |
Funding Finish | 2004 |
GNo | G0184864 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
20032 grants / $13,400
Investigation of a Brain Rhythm$11,000
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Professor Dirk Van Helden, Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2003 |
Funding Finish | 2003 |
GNo | G0182443 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Society for Neuroscience Annual General Meeting New Orleans USA 7-12 November 2003$2,400
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Travel Grant |
Role | Lead |
Funding Start | 2003 |
Funding Finish | 2003 |
GNo | G0183319 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
20021 grants / $11,000
Effects of altered genes on synaptic transmission in the intact nervous system$11,000
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Lead |
Funding Start | 2002 |
Funding Finish | 2002 |
GNo | G0181330 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
20016 grants / $75,286
Efferent modulation of hearing and the sense of balance$20,000
Funding body: Hunter Medical Research Institute
Funding body | Hunter Medical Research Institute |
---|---|
Project Team | Professor Alan Brichta, Conjoint Professor Robert Callister |
Scheme | Research Grant |
Role | Investigator |
Funding Start | 2001 |
Funding Finish | 2001 |
GNo | G0181165 |
Type Of Funding | Contract - Aust Non Government |
Category | 3AFC |
UON | Y |
Evaluation of Gene Delivery Methods in Brainstem Motoneurones$15,000
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Lead |
Funding Start | 2001 |
Funding Finish | 2001 |
GNo | G0180044 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Reciprocal Regulation of Kinases and Phosphatases in Long Term Synaptic Plasticity$15,000
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Emeritus Professor John Rostas, Professor Alistair Sim, Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2001 |
Funding Finish | 2001 |
GNo | G0180078 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Thermocycler with 96 well sample block for PCR reactions. Class II Biological Safety Cabinet. Liquid Nitrogen storage Dewar & Transport Dewar$11,770
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Emeritus Professor Peter Dunkley, Professor Alistair Sim, Professor Dirk Van Helden, Conjoint Professor Robert Callister |
Scheme | Equipment Grant |
Role | Investigator |
Funding Start | 2001 |
Funding Finish | 2001 |
GNo | G0181178 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
Thermocycler with 96 well sample block for PCR reactions. Class II Biological Safety Cabinet. Liquid Nitrogen storage Dewar & Transport Dewar$11,770
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Emeritus Professor Peter Dunkley, Professor Alistair Sim, Professor Dirk Van Helden, Conjoint Professor Robert Callister |
Scheme | University/NHMRC Equipment Grant Funds |
Role | Investigator |
Funding Start | 2001 |
Funding Finish | 2001 |
GNo | G0181179 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Annual Meeting of the Society of Nuroscience San Diego, USA 10-15 November, 2001$1,746
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Travel Grant |
Role | Lead |
Funding Start | 2001 |
Funding Finish | 2001 |
GNo | G0181585 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
20003 grants / $231,311
Cellular mechanisms underlying the sense of balance.$190,020
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Professor Alan Brichta, Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2000 |
Funding Finish | 2002 |
GNo | G0178493 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
Cellular Mechanisms Underlying the Sense of Balance.$30,291
Funding body: The Garnett Passe and Rodney Williams Memorial Foundation
Funding body | The Garnett Passe and Rodney Williams Memorial Foundation |
---|---|
Project Team | Professor Alan Brichta, Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 2000 |
Funding Finish | 2000 |
GNo | G0179041 |
Type Of Funding | Aust Competitive - Non Commonwealth |
Category | 1NS |
UON | Y |
Plasticity of inhibitory synaptic connections in the spastic mouse.$11,000
Funding body: ARC (Australian Research Council)
Funding body | ARC (Australian Research Council) |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Small Grant |
Role | Lead |
Funding Start | 2000 |
Funding Finish | 2000 |
GNo | G0178896 |
Type Of Funding | Scheme excluded from IGS |
Category | EXCL |
UON | Y |
19992 grants / $17,340
Physiological Properties of Glycine Receptors in Spastic Mice$13,990
Funding body: Ramaciotti Foundations
Funding body | Ramaciotti Foundations |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Research Grant |
Role | Lead |
Funding Start | 1999 |
Funding Finish | 1999 |
GNo | G0177964 |
Type Of Funding | Aust Competitive - Non Commonwealth |
Category | 1NS |
UON | Y |
Dr Stuart Douglas, Regents' Professor and Professor of Physiology, College of Medicine, University of Arizona, USA. 08/2/99 until 07/05/99$3,350
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Visitor Grant |
Role | Lead |
Funding Start | 1999 |
Funding Finish | 1999 |
GNo | G0178405 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
19982 grants / $127,496
Mechanisms underlying inhibitory glycinergic transmission in the central nervous system$111,496
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Conjoint Professor Robert Callister, Dr Pankaj Sah |
Scheme | Project Grant |
Role | Lead |
Funding Start | 1998 |
Funding Finish | 2000 |
GNo | G0177158 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
Physiology and anatomy of glycinergic synaptic connections in the central nervous system of spasmodic and spastic mice.$16,000
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Lead |
Funding Start | 1998 |
Funding Finish | 1998 |
GNo | G0177210 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
19973 grants / $26,433
Bridging Funding - Dr R J Callister$15,000
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Special Project Grant |
Role | Lead |
Funding Start | 1997 |
Funding Finish | 1997 |
GNo | G0177006 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Clycine receptor distribution on motoneurons of normal and spastic mice.$10,000
Funding body: ARC (Australian Research Council)
Funding body | ARC (Australian Research Council) |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Small Grant |
Role | Lead |
Funding Start | 1997 |
Funding Finish | 1997 |
GNo | G0176718 |
Type Of Funding | Scheme excluded from IGS |
Category | EXCL |
UON | Y |
Annual Meeting of the society of Neuroscience, USA, 25-30 October 1997$1,433
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Travel Grant |
Role | Lead |
Funding Start | 1997 |
Funding Finish | 1997 |
GNo | G0179414 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
19964 grants / $34,013
Bridging Funding$15,000
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Lead |
Funding Start | 1996 |
Funding Finish | 1996 |
GNo | G0177036 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Establishment of techniques for preparing genetically engineered molecules to study the regulation of neuronal and cellular function$12,000
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Emeritus Professor John Rostas, Emeritus Professor Peter Dunkley, Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 1996 |
Funding Finish | 1996 |
GNo | G0175744 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
The role of receptor-operated calcium influx in neuronal activity.$5,500
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister, Dr Pankaj Sah |
Scheme | Project Grant |
Role | Lead |
Funding Start | 1996 |
Funding Finish | 1996 |
GNo | G0175827 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Annual Meeting of the Society for Neuroscience$1,513
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Travel Grant |
Role | Lead |
Funding Start | 1996 |
Funding Finish | 1996 |
GNo | G0176909 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
19951 grants / $7,000
The structural basis of synaptic transmission$7,000
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Dr B Walmsley, Dr Madeleine Nicol, Conjoint Professor Robert Callister |
Scheme | Project Grant |
Role | Investigator |
Funding Start | 1995 |
Funding Finish | 1995 |
GNo | G0174923 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
19943 grants / $29,026
94 GRANT. Characterisation of synaptic currents in visualized neurons and presynaptic terminals.$15,957
Funding body: Ramaciotti Foundations
Funding body | Ramaciotti Foundations |
---|---|
Project Team | Conjoint Professor Robert Callister, Dr B Walmsley |
Scheme | Research Grant |
Role | Lead |
Funding Start | 1994 |
Funding Finish | 1994 |
GNo | G0173373 |
Type Of Funding | Aust Competitive - Non Commonwealth |
Category | 1NS |
UON | Y |
Synaptic transmission in neurons of the autonomic nervous system.$12,000
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | New Staff Grant |
Role | Lead |
Funding Start | 1994 |
Funding Finish | 1994 |
GNo | G0174622 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
Annual Meeting of the Society for Neuroscience, Miami, Florida USA, 13-18 November 1994$1,069
Funding body: University of Newcastle
Funding body | University of Newcastle |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Travel Grant |
Role | Lead |
Funding Start | 1994 |
Funding Finish | 1994 |
GNo | G0175186 |
Type Of Funding | Internal |
Category | INTE |
UON | Y |
19931 grants / $180,345
Mechanisms Underlying Synaptic Transmission in the Central Nervous System.$180,345
Funding body: NHMRC (National Health & Medical Research Council)
Funding body | NHMRC (National Health & Medical Research Council) |
---|---|
Project Team | Conjoint Professor Robert Callister |
Scheme | Postdoctoral Fellowship (Defunct) |
Role | Lead |
Funding Start | 1993 |
Funding Finish | 1996 |
GNo | G0173156 |
Type Of Funding | Aust Competitive - Commonwealth |
Category | 1CS |
UON | Y |
Research Supervision
Number of supervisions
Current Supervision
Commenced | Level of Study | Research Title | Program | Supervisor Type |
---|---|---|---|---|
2019 | PhD | Development of a Multilevel Analgesic Screening Approach Using Optogenetics to Activate and Study Pain Pathways | PhD (Human Physiology), Faculty of Health and Medicine, The University of Newcastle | Co-Supervisor |
2019 | PhD | Shedding New Light on How Projection Neurons Regulate Pain Signalling in the Spinal Cord and Brain | PhD (Human Physiology), Faculty of Health and Medicine, The University of Newcastle | Co-Supervisor |
2018 | PhD | Using a Multi-Technique Approach to Examine Functional, Anatomical and Transcriptomic Heterogeneity in Dorsal Horn Neurons | PhD (Human Physiology), Faculty of Health and Medicine, The University of Newcastle | Co-Supervisor |
2016 | PhD | Ion Channels in Melanoma | PhD (Medical Biochemistry), Faculty of Health and Medicine, The University of Newcastle | Co-Supervisor |
2015 | PhD | Model Perturbations of Glial Synaptomodulatory and Immune Functions | PhD (Anatomy), Faculty of Health and Medicine, The University of Newcastle | Co-Supervisor |
Past Supervision
Year | Level of Study | Research Title | Program | Supervisor Type |
---|---|---|---|---|
2019 | PhD | The Role of Parvalbumin+ Interneurons in Spinal Sensory Coding | PhD (Human Physiology), Faculty of Health and Medicine, The University of Newcastle | Co-Supervisor |
2018 | PhD | The Role of Calretinin Positive Interneurons in Spinal Sensory Coding | PhD (Human Physiology), Faculty of Health and Medicine, The University of Newcastle | Co-Supervisor |
2018 | PhD | Synaptic Properties of the Mammalian Peripheral Efferent Vestibular System | PhD (Anatomy), Faculty of Health and Medicine, The University of Newcastle | Co-Supervisor |
2017 | PhD | Investigation of Visceral Sensory Processing Mechanisms in the Superficial Dorsal Horn of the Spinal Cord | PhD (Anatomy), Faculty of Health and Medicine, The University of Newcastle | Principal Supervisor |
2015 | PhD | Electrophysiological Investigation of Spinal Cord Injury and Characterisation of Propriospinal Neurons | PhD (Anatomy), Faculty of Health and Medicine, The University of Newcastle | Co-Supervisor |
2012 | Masters | The Effect of Neck Muscle Inflammation on Neuronal Excitability in the Dorsal Horn of the Spinal Cord | M Philosophy (Anatomy), Faculty of Health and Medicine, The University of Newcastle | Principal Supervisor |
2011 | PhD | Electrophysiological Development of Superficial Dorsal Horn Neurons in Mice | PhD (Anatomy), Faculty of Health and Medicine, The University of Newcastle | Principal Supervisor |
2010 | PhD | Cannabinoid Signaling Mechanisms in the Central Nervous System | PhD (Anatomy), Faculty of Health and Medicine, The University of Newcastle | Principal Supervisor |
2007 | PhD | Inhibitory Synaptic Transmission in Mouse Medial Vestibular Nucleus Neurons | PhD (Anatomy), Faculty of Health and Medicine, The University of Newcastle | Co-Supervisor |
2007 | PhD | Inhibitory mechanisms in mouse medial vestibular nucleus neurons | Human Biology, University of Newcastle | Co-Supervisor |
2006 | PhD | Pain processing mechanisms in the superficial dorsal horn of the mouse spinal cord: in vivo and in vitro | PhD (Anatomy), Faculty of Health and Medicine, The University of Newcastle | Principal Supervisor |
2005 | Honours | The development of intrinsic properties in superficial dorsal horn neurons. | Human Biology, University of Newcastle | Co-Supervisor |
2004 | Honours | The role of altered inhibitory synaptic transmission in the vestibular system | Human Biology, University of Newcastle | Co-Supervisor |
2003 | Honours | The locus coeruleus: Action potential modulation in a neural network | Human Biology, University of Newcastle | Co-Supervisor |
2001 | Honours | Glycinergic and GABAAergic synaptic inhibition in superficial dorsal horn neurons in wild type, spastic and oscillator mice | Accounting, University of Newcastle | Principal Supervisor |
2000 | Honours | Development of GABAergic synaptic transmission in the norma and spastic mouse | Human Biology, University of Newcastle | Sole Supervisor |
1999 | Honours | The development of glycinergic synaptic connections in the spastic mouse | Human Biology, University of Newcastle | Sole Supervisor |
Conjoint Professor Robert Callister
Position
Conjoint Professor
Preclinical Neurobiology
School of Biomedical Sciences and Pharmacy
Faculty of Health and Medicine
Contact Details
robert.callister@newcastle.edu.au | |
Phone | 0438120954 |
Mobile | 0438120954 |
Office
Room | MS-415 (office), MS312 (lab) |
---|---|
Building | Medical Sciences |
Location | Callaghan University Drive Callaghan, NSW 2308 Australia |