Dr Jacqueline Iredale
Post Doctoral Researcher
School of Biomedical Sciences and Pharmacy
- Email:jacqueline.iredale@newcastle.edu.au
- Phone:0423272903
Career Summary
Biography
I am a Postdoctoral Researcher in the Behavioural Neuroscience Group, led by Dr. Lizzie Manning, Dr. Erin Campbell and Prof. Christopher Dayas. The work of the group focuses on understanding the neural mechanisms underlying neuropsychiatric disorders such as depression, substance use disorders, obsessive compulsive disorder and Tourette’s syndrome. My work currently focuses on two projects; investigation of the therapeutic mechanisms underlying transcranial magnetic stimulation (TMS) in the treatment of neuropsychiatric disorders, and investigating the effects of stress on specific brain regions and circuits using in vivo calcium imaging approaches.
Prior to commencing my role in the Behavioural Neuroscience Group, I recently completed a PhD (Human Physiology) in the Spinal Cord Connections lab led by Prof. Brett Graham. My PhD work focused on developing improved preclinical models of pain, both in vitro and in vivo, aiming to better understand the mechanisms underlying pain processing and to investigate the actions of known and novel analgesics. This work included an industry collaboration, utilising one of the models developed during my PhD to investigate the actions of novel cannabinoid compounds on spinal cord pain circuity.
Qualifications
- Doctor of Philosophy in Human Physiology, University of Newcastle
- Bachelor of Biomedical Sciences (Hons), University of Newcastle
Keywords
- Neuroscience
Languages
- English (Mother)
Fields of Research
| Code | Description | Percentage |
|---|---|---|
| 520202 | Behavioural neuroscience | 50 |
| 320903 | Central nervous system | 50 |
Professional Experience
UON Appointment
| Title | Organisation / Department |
|---|---|
| Casual ISSP Tutor Wollotuka | University of Newcastle Indigenous Education and Research Australia |
| Casual Academic | University of Newcastle School of Biomedical Sciences and Pharmacy Australia |
| Post Doctoral Researcher | University of Newcastle School of Biomedical Sciences and Pharmacy Australia |
Awards
Award
| Year | Award |
|---|---|
| 2023 |
IBRO-SfN Travel Award International Brain Research Organization (IBRO) |
| 2022 |
College Kindness Award - Anatomy Demonstrating University of Newcastle, College of Health Medicine and Wellbeing (CHMW) Research and Education Equipment Grant |
| 2022 |
Australian Pain Society (APS) PhD Student Travel Award Australian Pain Society |
Publications
For publications that are currently unpublished or in-press, details are shown in italics.
Journal article (6 outputs)
| Year | Citation | Altmetrics | Link | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025 |
Abiero AR, Gladding JM, Iredale JA, Drury HR, Manning EE, Dayas CV, Dhungana A, Ganesan K, Turner K, Becchi S, Kendig MD, Nolan C, Balleine B, Castorina A, Cole L, Clemens KJ, Bradfield LA, 'Dorsomedial striatal neuroinflammation causes excessive goal-directed action control by disrupting astrocyte function', Neuropsychopharmacology (2025)
|
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| 2022 |
Iredale JA, Stoddard JG, Drury HR, Browne TJ, Elton A, Madden JF, Callister RJ, Welsh JS, Graham BA, 'Recording Network Activity in Spinal Nociceptive Circuits using Microelectrode Arrays', Journal of Visualized Experiments (2022) [C1]
|
Open Research Newcastle | |||||||||
| 2021 |
Browne TJ, Smith KM, Gradwell MA, Iredale JA, Dayas CV, Callister RJ, Hughes DI, Graham BA, 'Spinoparabrachial projection neurons form distinct classes in the mouse dorsal horn', PAIN, 162, 1977-1994 (2021) [C1]
|
Open Research Newcastle | |||||||||
| 2020 |
Madden JF, Davis OC, Boyle KA, Iredale JA, Browne TJ, Callister RJ, Smith DW, Jobling P, Hughes DI, Graham BA, 'Functional and Molecular Analysis of Proprioceptive Sensory Neuron Excitability in Mice', Frontiers in Molecular Neuroscience, 13, 1-13 (2020) [C1]
|
Open Research Newcastle | |||||||||
| 2020 |
Browne TJ, Gradwell MA, Iredale JA, Maden JF, Callister RJ, Hughes DI, Dayas CV, Graham BA, 'Transgenic Cross-Referencing of Inhibitory and Excitatory Interneuron Populations to Dissect Neuronal Heterogeneity in the Dorsal Horn', Frontiers in Molecular Neuroscience, 13, 1-20 (2020) [C1]
|
Open Research Newcastle | |||||||||
| 2019 |
Smith KM, Browne TJ, Davis OC, Coyle A, Boyle KA, Watanabe M, Dickinson SA, Iredale JA, Gradwell MA, Jobling P, Callister RJ, Dayas CV, Hughes DI, Graham BA, 'Calretinin positive neurons form an excitatory amplifier network in the spinal cord dorsal horn', ELIFE, 8 (2019) [C1]
|
Open Research Newcastle | |||||||||
| Show 3 more journal articles | |||||||||||
Preprint (5 outputs)
| Year | Citation | Altmetrics | Link | |||||
|---|---|---|---|---|---|---|---|---|
| 2025 |
Iredale J, Brown A, Yadav T, Sonkusare S, Dunlop A, Dayas C, Manning E, Campbell E, 'Repetitive transcranial magnetic stimulation for alcohol use disorder – can parameter selection be leveraged to optimise treatment?' (2025)
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| 2024 |
Mitchell CS, Mohammadkhani A, Manning EE, Campbell EJ, Fisher SD, Yeoh JW, Pearl AJ, Burton NJ, Qiao M, Iredale JA, Bains JS, McNally GP, Andrews ZA, Graham BA, Scammell TE, Lowell BB, Kong D, Borgland SL, Dayas CV, 'Neurons in the ventral striatopallidal complex modulate lateral hypothalamic orexin/hypocretin neuron activity: Implications for reward-seeking' (2024)
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| 2024 |
Abiero AR, Gladding J, Iredale J, Drury H, Manning E, Dayas C, Dhungana A, Ganesan K, Turner K, Becchi S, Kendig M, Nolan C, Balleine B, Castorina A, Cole L, Clemens K, Bradfield L, 'Dorsomedial striatal neuroinflammation causes excessive goal-directed action control by disrupting astrocyte function' (2024)
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| Show 2 more preprints | ||||||||
Grants and Funding
Summary
| Number of grants | 5 |
|---|---|
| Total funding | $88,838 |
Click on a grant title below to expand the full details for that specific grant.
20235 grants / $88,838
MEA2100-MiniHS120 miniature microelectrode array workstation$35,972
Funding body: University of Newcastle, College of Health Medicine and Wellbeing (CHMW) Research and Education Equipment Grant
| Funding body | University of Newcastle, College of Health Medicine and Wellbeing (CHMW) Research and Education Equipment Grant |
|---|---|
| Project Team | Rebecca Lim |
| Scheme | CHMW Research and Education Equipment Grant |
| Role | Investigator |
| Funding Start | 2023 |
| Funding Finish | 2023 |
| GNo | |
| Type Of Funding | Internal |
| Category | INTE |
| UON | N |
An Optogenetic Mouse model for pre-clinical pain therapeutics screening: A proof of concept study to treat Neuropathic pain$23,253
Funding body: University of Newcastle
| Funding body | University of Newcastle |
|---|---|
| Project Team | Professor Brett Graham, Doctor Jacqueline Iredale |
| Scheme | Industry Matched Funding Scheme |
| Role | Investigator |
| Funding Start | 2023 |
| Funding Finish | 2023 |
| GNo | G2300407 |
| Type Of Funding | Internal |
| Category | INTE |
| UON | Y |
Establishing a translational TMS research cluster$19,313
Funding body: Hunter Medical Research Institute (HMRI)
| Funding body | Hunter Medical Research Institute (HMRI) |
|---|---|
| Project Team | Dr Lizzie Manning, Dr Amanda Brown, Dr Tarun Yadav, Prof Christopher Dayas |
| Scheme | HMRI Equipment Grant |
| Role | Lead |
| Funding Start | 2023 |
| Funding Finish | 2023 |
| GNo | |
| Type Of Funding | Internal |
| Category | INTE |
| UON | N |
The Mike and Karin Calford Travel Fellowship$6,500
Funding body: Hunter Medical Research Institute
| Funding body | Hunter Medical Research Institute |
|---|---|
| Project Team | Doctor Jacqueline Iredale, Doctor Jacqueline Iredale |
| Scheme | Research Grant |
| Role | Lead |
| Funding Start | 2023 |
| Funding Finish | 2023 |
| GNo | G2301210 |
| Type Of Funding | Scheme excluded from IGS |
| Category | EXCL |
| UON | Y |
IBRO-SfN Travel Grant$3,800
Funding body: International Brain Research Organization (IBRO)
| Funding body | International Brain Research Organization (IBRO) |
|---|---|
| Scheme | SFN Travel Award |
| Role | Lead |
| Funding Start | 2023 |
| Funding Finish | 2023 |
| GNo | |
| Type Of Funding | International - Competitive |
| Category | 3IFA |
| UON | N |
Research Supervision
Number of supervisions
Current Supervision
| Commenced | Level of Study | Research Title | Program | Supervisor Type |
|---|---|---|---|---|
| 2023 | PhD | Resetting Hypothalamic circuits to Treat Depression | PhD (Anatomy), College of Health, Medicine and Wellbeing, The University of Newcastle | Co-Supervisor |
| 2022 | PhD | Developing Therapeutic Options for Chronic Pelvic Pain | PhD (Human Physiology), College of Health, Medicine and Wellbeing, The University of Newcastle | Co-Supervisor |
Dr Jacqueline Iredale
Positions
Post Doctoral Researcher
Preclinical Neurobiology Group
School of Biomedical Sciences and Pharmacy
College of Health, Medicine and Wellbeing
Casual Academic
Preclinical Neurobiology Group
School of Biomedical Sciences and Pharmacy
College of Health, Medicine and Wellbeing
Casual ISSP Tutor Wollotuka
Preclinical Neurobiology Group
Indigenous Education and Research
Engagement and Equity Division
Contact Details
| jacqueline.iredale@newcastle.edu.au | |
| Phone | 0423272903 |
| Mobile | 0423272903 |
| Link |
Office
| Room | MS508A |
|---|---|
| Building | Medical Science |
| Location | Callaghan Campus University Drive Callaghan, NSW 2308 Australia |
