The University of Newcastle, Australia

NHMRC funding success 2016

Friday, 13 November 2015

Dr Lei Jin has been awarded more than $401,000 in NHMRC Project Grant funding commencing in 2016 for his research project Alpha-actinin-4 as an oncogenic driver and therapeutic target in melanoma.

NHMRC

About the project

Despite the recent advances in targeted therapy and immunotherapy, curative treatment of metastatic melanoma remains an unmet health problem.  In this project, we will potentially demonstrate that a protein called ACTN4 is abnormally expressed at high levels in melanoma cells and plays an important role for melanoma cell survival and resistance to treatment, and thus identify inhibition of ACTN4, either alone or in combination with other drugs, as a novel approach in the treatment of melanoma.

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