Services
NewHOPE integrates organoids and cell lines from three specialised biobanks - the Digestive Health Biobank (DHB), Respiratory Health Biobank (RHB), and Kidney and Urinary Biobank (KUB) - to provide a comprehensive human tissue platform for research.
Digestive Health Biobank
This biobank provides a rich resource of human samples and detailed clinical data to support research into gastrointestinal disorders.
Diseases covered
- Inflammatory Bowel Disease (IBD)
- Irritable Bowel Syndrome (IBS)
- Coeliac disease
- Functional Dyspepsia (FD)
- Reflux
- Esophagitis
- Eosinophilic disorders
- Healthy controls.
Samples collected
- Blood
- Stool
- Tissue biopsies
- Intestinal organoids.
Clinical information included:
- Disease subtyping
- Microbiome data
- Diet.
Respiratory health Biobank (RHB)
This biobank provides a comprehensive collection of respiratory samples and detailed clinical data to support research into airway diseases.
Diseases covered
- Asthma
- Bronchiectasis
- Chronic Obstructive Pulmonary Disease (COPD)
- Healthy controls (smokers and non-smokers).
Samples collected
- Blood
- Airway brushings
- Nasal brushings
- Sputum
- Tissue biopsies
- Cheek swabs
- Pleural fluid
- Bronchoalveolar Lavage (BAL)
- Primary Bronchial Epithelial Cells (pBEC)
- Conditionally Reprogrammed (CR) Cells.
Clinical information included
- Lung function
- Disease severity
- Immune phenotypes.
Kidney and Urinary Biobank (KUB)
This biobank provides a valuable resource of biological samples and comprehensive clinical data to support research into kidney and urinary tract diseases.
Diseases Covered
- Chronic Kidney Disease (CKD)
- End-Stage Renal Disease (ESRD)
- Urinary Tract Diseases
- Kidney Replacement Therapy (Dialysis or Transplant)
- Kidney Donors
- Healthy Controls.
Samples collected
- Blood
- Urine
- Kidney tissue
- Urinary and bladder tissue.
Clinical information included
- Kidney and urinary function tests
- Tissue histology
- Transplant status
- Disease subtyping.
The University of Newcastle acknowledges the traditional custodians of the lands within our footprint areas: Awabakal, Darkinjung, Biripai, Worimi, Wonnarua, and Eora Nations. We also pay respect to the wisdom of our Elders past and present.