Available in 2018
Course code

PHAR3103

Units

10 units

Level

3000 level

Course handbook

Description

Presents the pathophysiology of altered health states and their management including both pharmacological and non-pharmacological interventions. Specific conditions covered in this course include neurological and mental health conditions, including head injuries as well as infectious diseases affecting the CNS. Concepts around the use of illicit drugs and drug abuse are also covered in this course. The course considers aspects of pharmacy practice including a systematic review of prescription and non-prescription medications and Complementary and Alternate Medicines, which will address the quality use of medicines in the management of these conditions.

The course builds on student's existing knowledge and understanding of the physical pharmacy principles and provides students with an understanding of how these principles are applied to the preparation of dosage formulations used in the management of conditions affecting the neurological system and mental health conditions. The stability of these drug products and factors influencing the storage and shelf life of products is included in this course. The clinical application of depot injections and wafer formulations will be discussed and expanded upon in this course.

Pharmacokinetic and Pharmacodynamic considerations in conditions affecting the neurological system and mental health conditions are covered including therapeutic drug monitoring, clinically significant pharmacokinetic drug interactions and advanced concepts in drug metabolism.

Application of the knowledge developed in this course will be complemented by clinical skills training.


Availability

Callaghan

  • Semester 1 - 2018

Learning outcomes

On successful completion of the course students will be able to:

1. Describe the pathophysiology and management (pharmacological and non-pharmacological) of conditions affecting the neurological system and mental health conditions.

2. Describe the pathophysiology and pharmacology of illicit drugs and understand the principles underlying the misuse of non-prescription and prescription medications.

3. Describe the quality use of medicines and issues surrounding these therapeutic agents in the treatment of these conditions and continue to develop clinical skills and communication skills in the therapeutic management of these conditions.

4. Develop skills in the appropriate use of non-prescription products and advice on non-pharmacological treatment options in the management of these conditions.

5. Describe the formulation and manufacture of dosage formulations used in conditions affecting the neurological system and mental health conditions including long acting formulations such as depot injections and HBS dosage forms, as well as wafer formulations.

6. Describe the role of pharmacodynamics and pharmacokinetic factors that need to be considered in conditions affecting the neurological system and mental health conditions including therapeutic drug concentrations, clinically significant pharmacokinetic drug interactions and concepts in drug metabolism.


Content

1. This course will cover the pathophysiology, therapeutic management (pharmacological and non-pharmacological ) and pharmacy practice issues in the management of:

  • Neurological conditions (including headache, seizures disorders, neurodegenerative disorders and pain management).
  • Mental health conditions (including anxiety, schizophrenia, depression, drug addition, attention deficit hyperactivity disorder and sleep disorder).
  • Head injury.

2. The concept of minor illness and major disease will be discussed, including the use of prescription and non-prescription products, including Complementary and Alternate Medicines. Non-pharmacological approaches to the management of these conditions will also be discussed.

3. The pathophysiology and pharmacology of illicit drugs and principles underlying the misuse of non-prescription and prescription medications:

  • Intoxication and overdose of licit and illicit drugs.
  • Drug addiction and physical dependence arising from the regular use of prescription and non-prescription medications.

4. The course covers all pharmacokinetic and pharmacodynamics considerations for therapeutic agents used in the management of conditions affecting the neurological system and mental health including therapeutic drug monitoring, clinically significant pharmacokinetic/pharmacodynamic drug interactions and the clinical application of advanced concepts in drug metabolism, such as auto-induction and non-linear kinetics.


Requisite

This course is only available to students enrolled in the Bachelor of Pharmacy (Honours) program. Pre-requisite - successful completion of PHAR1101 and PHAR1201


Assumed knowledge

PHAR2204 Clinical Pharmacotherapy 1


Assessment items

Formal Examination: Formal written examination *

In Term Test: Mid term examination *

Quiz: Online quizzes

* This assessment has a compulsory requirement.


Compulsory Requirements

In order to pass this course, each student must complete ALL of the following compulsory requirements:

Course Assessment Requirements:

  • In Term Test: Pass Requirement - Students must pass this assessment item to pass the course. - Students must pass the combined mid-term and final examination assessment items to pass the course.
  • Formal Examination: Pass Requirement - Students must pass this assessment item to pass the course. - Students must pass the combined mid-term and final examination assessment items to pass the course.

Contact hours

Callaghan

Lecture

Face to Face On Campus 3 hour(s) per Week for 10 Weeks

Includes in-class exam

Tutorial

Face to Face On Campus 2 hour(s) per Week for 9 Weeks