Presents the pathophysiology of altered health states and their management including both pharmacological and non-pharmacological interventions. Specific conditions covered in this course include neurological and mental health conditions, including head injuries and the control of intracranial pressure. Concepts around the use of illicit drugs and drug abuse are also covered in this course. The course considers aspects of pharmacy practice including a systematic review of prescription and non-prescription medications and will address the quality use of medicines in the management of these conditions.
The course builds on students' existing knowledge and understanding of the physical pharmacy principles and provides students with an understanding of how these principles are applied to the preparation of dosage formulations used in the management of conditions affecting the neurological system and mental health conditions. The clinical application of depot injections and wafer formulations will be discussed and expanded upon in this course.
Pharmacokinetic and Pharmacodynamic considerations in conditions affecting the neurological system and mental health conditions are covered including therapeutic drug monitoring, clinically significant pharmacokinetic drug interactions and advanced concepts in drug metabolism. The course will further build on knowledge of pharmacokinetics including drug dosage calculations with a particular focus on drugs used in the treatment of epilepsy.
Application of the knowledge developed in this course will be complemented by clinical skills training.
Availability2021 Course Timetables
- Semester 1 - 2021
On successful completion of the course students will be able to:
1. Describe the pathophysiology and management (pharmacological and non-pharmacological) of conditions affecting the neurological system and mental health conditions.
2. Describe the quality use of medicines and issues surrounding these therapeutic agents in the treatment of these conditions and continue to develop clinical skills and communication skills in the therapeutic management of these conditions.
3. Describe the pathophysiology and pharmacology of illicit drugs and understand the principles underlying the misuse of medications.
4. Develop skills in the appropriate use of non-prescription products and advice on non-pharmacological treatment options in the management of these conditions.
5. Describe the formulation and manufacture of dosage formulations used in conditions affecting the neurological system and mental health conditions including long acting formulations such as depot injections.
6. Describe the role of pharmacodynamics and pharmacokinetic factors that need to be considered in conditions affecting the neurological system and mental health conditions including therapeutic drug concentrations, clinically significant pharmacokinetic drug interactions and concepts in drug metabolism with a particular focus on anti-seizure medications.
1. This course will cover the pathophysiology, therapeutic management (pharmacological and non-pharmacological ) and pharmacy practice issues in the management of:
- Neurological conditions (including headache, seizures disorders, neurodegenerative disorders and pain management).
- Mental health conditions (including anxiety, schizophrenia, depression, drug addition, attention deficit hyperactivity disorder and sleep disorder).
- Head injury, intracranial pressure and stroke.
2. The concept of minor illness and major disease will be discussed, including the use of prescription and non-prescription products.
3. The pathophysiology and pharmacology of illicit drugs and principles underlying the misuse and dependence:
- Intoxication and overdose of licit and illicit drugs.
- Drug addiction and physical dependence arising from the regular use of prescription and non-prescription medications.
4. The course covers all pharmacokinetic and pharmacodynamics considerations for therapeutic agents used in the management of conditions affecting the neurological system and mental health including therapeutic drug concentrations, clinical application of advanced concepts in drug metabolism, such as auto-induction and non-linear kinetics, particularly with application to anti-seizure medication.
To enrol in this course students must have successfully completed either MATH1110 or STAT1070 all 1000 and 2000 level courses in the Bachelor of Pharmacy (Honours) (12328) program and be active in this program.
PHAR2204 Clinical Pharmacotherapy 1
Formal Examination: Formal written examination *
In Term Test: Mid-term examination *
Quiz: Online quizzes
* This assessment has a compulsory requirement.
In order to pass this course, each student must complete ALL of the following compulsory requirements:
Course Assessment Requirements:
- In Term Test: Pass Requirement - Students must pass this assessment item to pass the course. - Students must pass the combined mid-term and final examination assessment items to pass the course.
- Formal Examination: Pass Requirement - Students must pass this assessment item to pass the course. - Students must pass the combined mid-term and final examination assessment items to pass the course.
Face to Face On Campus 3 hour(s) per Week for 10 Weeks
Includes in-class exam
Face to Face On Campus 2 hour(s) per Week for 10 Weeks
The University of Newcastle acknowledges the traditional custodians of the lands within our footprint areas: Awabakal, Darkinjung, Biripai, Worimi, Wonnarua, and Eora Nations. We also pay respect to the wisdom of our Elders past and present.