Available in 2021
Course code



10 units


3000 level

Course handbook


Presents the pathophysiology of altered health states and their management including both pharmacological and non-pharmacological interventions. Specific conditions covered in this course include diabetes, thyroid, pituitary and adrenal conditions. The course considers aspects of pharmacy practice including a systematic review of prescription and non-prescription medications and complementary and alternate medicines, which will address the quality use of medicines in the management of these conditions.

The course builds on student's existing knowledge and understanding of the principles of physical pharmacy and provides students with an understanding of how these principles are applied to the preparation of injectable dosage formulations. The stability of these drug products and factors influencing the storage and shelf life of products is included in this course. In considering the formulation of injectable dosage formulations and sterile drug products, the clinical application of aseptic technique, isotonicity, stability and incompatibilities of parenteral formulations will be discussed and expanded upon in this course.

Pharmacokinetic and pharmacodynamic considerations in conditions affecting the endocrine system are covered including the kinetics of parenteral drug administration.

Application of the knowledge developed in this course will be complemented by clinical skills training.

Availability2021 Course Timetables


  • Semester 1 - 2021

Learning outcomes

On successful completion of the course students will be able to:

1. Describe the pathophysiology and management (pharmacological and non-pharmacological) of diabetes.

2. Describe the pathophysiology and management of thyroid, parathyroid, pituitary and adrenal conditions.

3. Describe the quality use of medicines' issues surrounding these therapeutic agents in the treatment of these conditions and continue to develop clinical skills and communication skills in the therapeutic management of these conditions.

4. Identify the principles of drug stability and discuss pharmacy practice issues relating to storage of injectable drug products.

5. Describe the formulation and manufacture of injectable dosage forms and sterile drug products.

6. Understand the skills required in the preparation of aseptic injectable pharmaceutical products and issues surrounding drug compatibility and isotonicity.

7. Use advanced pharmaceutical principles to help avoid drug interactions and incompatibilities, in particular for intravenous formulations.

8. Describe the pharmacodynamic and pharmacokinetic factors as determinants of drug response in conditions affecting the endocrine system, and of injectable formulations.

9. Develop an understanding of the pharmacology, design and delivery of medicines used in veterinary practice.


1. This course will cover the pathophysiology, therapeutic management (pharmacological and non-pharmacological) and pharmacy practice issues in the management of:

-  Conditions of thyroid , adrenal, pituitary, and hypothalamus.

-  Diabetes.

2. The concept of minor illness and major disease will be discussed, including the use of prescription and non-prescription products, including Complementary and Alternate Medicines. Non-pharmacological approaches to the management of these conditions will also be discussed.

3. The course covers advanced concepts in formulation development and design of injectable preparations including:

-  Sterile products, aseptic technique, microbial contamination, spoilage and preservation, principles of sterilisation and storage considerations.

-  Advanced dispensing skills in the aseptic preparation of injectable pharmaceutical products.

-  Drug interactions and incompatibilities particularly for intravenous formulations.

-  Isotonicity.

4. The course covers all pharmacokinetic/pharmacodynamic considerations for therapeutic agents used in the management of conditions affecting the endocrine system including:

-  Pharmacokinetic considerations in IV bolus dosing and IV infusion.

-  Extravascular dosing and subcutaneous drug administration.

5. The principles of veterinary medicine including:

-  Pharmacology of medicines used in veterinary practice.

-  The design and delivery of medicines used in veterinary practice.


To enrol in this course students must have successfully completed either MATH1110 or STAT1070 all 1000 and 2000 level courses in the Bachelor of Pharmacy (Honours) (12328) program and be active in this program.

Assumed knowledge

PHAR2204 Clinical Pharmacotherapy 1

Assessment items

Formal Examination: Written exam *

In Term Test: In Term Examination

Quiz: Tutorial Minitest quizzes

* This assessment has a compulsory requirement.

Compulsory Requirements

In order to pass this course, each student must complete ALL of the following compulsory requirements:

Course Assessment Requirements:

  • Formal Examination: Pass Requirement - Students must pass this assessment item to pass the course.

Contact hours



Face to Face On Campus 30 hour(s) per Term Full Term

includes in term examinations


Face to Face On Campus 2 hour(s) per Week for 10 Weeks

The University of Newcastle acknowledges the traditional custodians of the lands within our footprint areas: Awabakal, Darkinjung, Biripai, Worimi, Wonnarua, and Eora Nations. We also pay respect to the wisdom of our Elders past and present.