Provides students with an understanding of the physical pharmacy principles applied to the preparation of liquid and semi-solid dosage forms. This includes the principles applied to solutions, suspensions and emulsions, including surface tension, interfacial phenomena, surfactants, adsorption and pH. An introduction to concepts around stability/degradation and storage/preservation will also be explored. The course builds on existing knowledge in pharmaceutics looking at veterinary compounding and manufacture.
An introduction to the basic concepts of pharmacology and how they are applicable to the practice of pharmacy is covered, including receptor pharmacology and an introduction to the autonomic nervous system. Basic pharmacokinetic principles are introduced and the link between pharmacokinetics and pharmacodynamics is explored.
This course is a Compulsory Program Component that students must pass in order to progress in the Bachelor of Pharmacy (Honours) program.
- Semester 1 - 2019
On successful completion of the course students will be able to:
1. Describe the physiochemical factors affecting solutions, suspensions and emulsions.
2. Describe the use of medicines in veterinary practice and the principles of veterinary compounding and manufacture.
3. Understand the basic principles of stability and degradation.
4. Understand the basic principles of storage and preservation.
5. Identify the factors influencing the rate and extent of dissolution of a drug.
6. Describe the different types of polyphasic liquid and semi-solid dosage forms used in therapeutics.
7. Discuss the influence of chemical properties of drugs and excipients on the physicochemical properties of liquid dosage forms.
8. Describe the use of pharmaceutical excipients in dosage form design.
9. Describe the application of the basic pharmacological concepts in the management of patients.
10. Describe the basic ADME (absorption, distribution, metabolism and excretion) principles of pharmacokinetics and pharmacodynamics.
11. Discuss how pharmacodynamics and pharmacokinetics are interrelated.
- Solubility and factors influencing dissolution.
- Biopharmaceutical importance of particle size.
- Osmotic properties of drug solutions.
- Surface and interfacial properties of surfactants.
- Emulsions, suspensions and other dispersions.
- Excipients including preservatives.
- Key principles of surface activity, preservation of multiphase systems, adsorption and rheology of pharmaceutical systems.
- An introduction to the basic concepts of pharmacology and how they apply to pharmacy, including an introduction to receptor pharmacology.
- The pharmacology of the autonomic nervous system.
- The absorption, distribution, metabolism and excretion (ADME) principles of pharmacokinetics.
- An introduction to pharmacodynamics.
- Concepts in veterinary medicine, compounding and manufacture.
Formal Examination: Formal Exam *
In Term Test: Examination: Mid-Semester
Quiz: Quiz - Class
* This assessment has a compulsory requirement.
In order to pass this course, each student must complete ALL of the following compulsory requirements:
General Course Requirements:
- Practical: Induction Requirement - Students must attend and pass the induction requirements before attending these sessions. - In order to participate in this course students must complete a compulsory safety induction.
Course Assessment Requirements:
- Formal Examination: Pass Requirement - Students must pass this assessment item to pass the course.
Face to Face On Campus 3 hour(s) per Week for 12 Weeks
Face to Face On Campus 2 hour(s) per Week for 12 Weeks