Available in 2018

Course handbook


Provides an introduction to the concept of human disease and the pathophysiological mechanisms underlying the causes. Students will be provided with an introduction to pathophysiology of the immune, nervous, endocrine, skeletal, gastrointestinal, renal, vascular and respiratory systems. Associated pathologies of these systems will be introduced and explored.

Availability2018 Course Timetables


  • Semester 1 - 2018


  • Semester 1 - 2018

Learning outcomes

On successful completion of the course students will be able to:

1. Develop an understanding of the concept of human disease.

2. Develop an understanding of the pathology and pathophysiology associated with disorders of the immune, nervous, endocrine, skeletal, renal, respiratory, gastrointestinal & cardiovascular systems.

3. Develop an understanding of the pathophysiological mechanisms and processes underlying human diseases.


Students will initially be introduced to the concepts of disease and to the mechanisms by which cells undergo injury and adapt to such insult.

This will be followed by a module comprising an overview of immune effector function, inflammation and hypersensitivity, immune responses to pathogenic agents, autoimmunity and immunodeficiency.

The second module will consider pathophysiological mechanisms underlying disorders of blood and the lymphatic system together with an introduction to mechanisms underlying neoplasms.

Module three explores cardiovascular disease and includes consideration of the consequences of ischaemic heart disease, heart failure, disorders of electroconduction and common vascular disorders.

Module four involves the respiratory system and will focus on acute pulmonary syndromes, restrictive and obstructive disease.

Module five will discuss upper and lower gastrointestinal tract pathophysiology. Renal pathophysiology, including aspects of acute and chronic renal failure and some common diseases that affect kidney function will also be considered in this module.

Module six considers endocrine disorders, in particular the pathophysiology of diabetes mellitus.

Module seven will explore the mechanisms underlying pathophysiology of the musculoskeletal system and neurological dysfunction, including the autonomic nervous system, at both the cellular and systems level as occurs in stroke, space occupying lesions, degenerative disorders and with injury to peripheral and central elements of the nervous system.

Assumed knowledge

HUBS1403 Biomedical Sciences Part 1 and HUBS1404 Biomedical Science Part 2 OR HUBS1401 Human Bioscience 1A and HUBS1402 Human Bioscience 1B or equivalent

Assessment items

In Term Test: Intra-semester exams (x2) *

Formal Examination: Final exam *

* This assessment has a compulsory requirement.

Compulsory Requirements

In order to pass this course, each student must complete ALL of the following compulsory requirements:

Course Assessment Requirements:

  • Formal Examination: Attempt / Submission Requirement - Students must attempt/submit this assessment item to pass the course.
  • In Term Test: Attempt / Submission Requirement - Students must attempt/submit this assessment item to pass the course.

Contact hours

Callaghan and Ourimbah


Face to Face On Campus 3 hour(s) per Week for 12 Weeks


Face to Face On Campus 1 hour(s) per Week for 12 Weeks

Includes in term examination